Epigenetics @HelmholtzMunich
Dozens of researchers @Helmholtz Munich join forces to reveal the myriad of secrets of Epigenetics.
Learn more about us below.
Dozens of researchers at Helmholtz Munich joined forces
to reveal the myriad of secrets of Epigenetics.
The Epigenetics@HelmholtzMunich Community Research consists of almost 30 labs from 17 Helmholtz Munich institutes, committed all to performing ground-breaking research in the field of epigenetics. These groups are pioneers in their respective disciplines, utilizing cutting edge techniques to answer the complex questions of today.
The topics studied by the community include: stem cells, cellular plasticity, metabolism, diabetes, computational biology, epidemiology, immunology, development and systems biology.
Seminars & Events
Recent Publications
Dasdelen, M.F. ; Lim, H. ; Buck, M. ; Götze, K.S. ; Marr, C. ; Schneider, S.
CytoSAE: Interpretable Cell Embeddings for Hematology.Firsova, A.B. ; Marco Salas, S. ; Kuemmerle, L. ; Abalo, X.M. ; Sountoulidis, A. ; Larsson, L. ; Mahbubani, K.T. ; Theelke, J. ; Andrusivova, Z. ; Alonso Galicia, L. ; Liontos, A. ; Balassa, T. ; Kovács, F. ; Horvath, P. ; Chen, Y. ; Gote-Schniering, J. ; Stoleriu, M.-G. ; Behr, J. ; Meyer, K.B. ; Timens, W. ; Schiller, H.B. ; Luecken, M. ; Theis, F.J. ; Lundeberg, J. ; Nilsson, M. ; Nawijn, M.C. ; Samakovlis, C.
Spatial single-cell atlas reveals regional variations in healthy and diseased human lung.Kukhtevich, I. ; Persson, S. ; Padovani, F. ; Schneider, R. ; Cvijovic, M. ; Schmoller, K.M.
The origin of septin ring size control in budding yeast.Boerstler, T. ; Kachkin, D. ; Gerasimova, E. ; Zagha, N. ; Furlanetto, F. ; Nayebzade, N. ; Zappia, L. ; Boisvert, M. ; Farrell, M. ; Ploetz, S. ; Prots, I. ; Regensburger, M. ; Günther, C. ; Winkler, J. ; Gupta, P. ; Theis, F.J. ; Karow, M. ; Falk, S. ; Winner, B. ; Krach, F.
Deciphering brain organoid heterogeneity by identifying key quality determinants.Ratajczak, F. ; Heinig, M. ; Falter-Braun, P.
Exploring the omnigenic architecture of selected complex traits.Voss, C. ; Han, L. ; Ansari, M. ; Strunz, M. ; Haefner, V. ; Angelidis, I. ; Mayr, C.H. ; Berthing, T. ; Zhou, Q. ; Günther, E. ; Huzain, O. ; Schmid, O. ; Vogel, U. ; Schniering, J. ; Gaedcke, S. ; Theis, F.J. ; Schiller, H.B. ; Stöger, T.
Toward a ToxAtlas of carbon-based nanomaterials: Single-cell RNA sequencing reveals initiating cell circuits in pulmonary inflammation.Bhattacharya, D. ; da Silva Buttkus, P. ; Nalbach, K. ; Cheng, L. ; Garrett, L. ; Irmler, M. ; Kislinger, G. ; Werner, G. ; Rodde, R. ; Lengger, C. ; Beckers, J. ; Zimprich, A. ; Hölter, S.M. ; Gailus-Durner, V. ; Fuchs, H. ; Hrabě de Angelis, M. ; Wefers, B. ; Wurst, W. ; Brill, M.S. ; Schifferer, M. ; Lichtenthaler, S.F. ; Behrends, C.
Neuropathy-associated Tecpr2 mutation knock-in mice reveal endolysosomal loss of function phenotypes in neurons and microglia.Hennes, M. ; Richter, M. ; Fischer-Sternjak, J. ; Götz, M.
Astrocyte diversity and subtypes: Aligning transcriptomics with multimodal perspectives.Tejada Lapuerta, A. ; Schaar, A. ; Gutgesell, R.M. ; Palla, G. ; Halle, L. ; Minaeva, M. ; Vornholz, L. ; Dony, L. ; Drummer, F. ; Richter, T. ; Bahrami, M. ; Theis, F.J.
Nicheformer: A foundation model for single-cell and spatial omics.Hrovatin, K. ; Moinfar, A.A. ; Zappia, L. ; Parikh, S. ; Tejada Lapuerta, A. ; Lengerich, B. ; Kellis, M. ; Theis, F.J.
Integrating single-cell RNA-seq datasets with substantial batch effects.Martinez-Reza, M.F. ; Götz, M.
Wrap it up: Myelination of transplanted neurons for repair.DeMeo, B. ; Nesbitt, C. ; Miller, S.A. ; Burkhardt, D.B. ; Lipchina, I. ; Fu, D. ; Holderreith, P. ; Kim, D. ; Kolchenko, S. ; Szalata, A. ; Gupta, I. ; Kerr, C. ; Pfefer, T.J. ; Rojas-Rodriguez, R. ; Kuppassani, S. ; Kruidenier, L. ; Doshi, P.B. ; Zamanighomi, M. ; Collins, J.J. ; Shalek, A.K. ; Theis, F.J. ; Cortes, M.
Active learning framework leveraging transcriptomics identifies modulators of disease phenotypes.Yang, K. ; Spitzer, H. ; Sterr, M. ; Hrovatin, K. ; de la O, S. ; Zhang, X. ; Setyono, E.S.A. ; Ud-Dean, M. ; Walzthoeni, T. ; Flisikowski, K. ; Flisikowska, T. ; Schnieke, A. ; Scheibner, K. ; Wells, J.M. ; Sneddon, J.B. ; Kessler, B. ; Wolf, E. ; Kemter, E. ; Theis, F.J. ; Lickert, H.
A multimodal cross-species comparison of pancreas development.Schmid, K.T. ; Symeonidi, A. ; Hlushchenko, D. ; Richter, M.L. ; Tijhuis, A.E. ; Foijer, F. ; Colomé-Tatché, M.
Benchmarking scRNA-seq copy number variation callers.Hingerl, J.C. ; Martens, L.D. ; Karollus, A. ; Manz, T. ; Buenrostro, J.D. ; Theis, F.J. ; Gagneur, J.
scooby: Modeling multi-modal genomic profiles from DNA sequence at single-cell resolution.Vilov, S. ; Heinig, M.
Investigating the performance of foundation models on human 3'UTR sequences.Ali, M. ; Richter, S. ; Ertürk, A. ; Fischer, D.S. ; Theis, F.J.
Graph neural networks learn emergent tissue properties from spatial molecular profiles.Träuble, K. ; Munz, M. ; Pauli, J. ; Sachs, N. ; Vafadarnejad, E. ; Carrillo-Roa, T. ; Maegdefessel, L. ; Kastner, P. ; Heinig, M.
Integrated single-cell atlas of human atherosclerotic plaques.