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Helmholtz Munich | ©Bartzsch
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Molecular Targets and Therapeutics Center Institute of Radiation Medicine

The Institute of Radiation Medicine (IRM) at Helmholtz Munich covers all aspects of modern radiation research and focuses on translational issues and clinical applications.

The focus of our highly interdisciplinary team of physicists, biologists, medical doctors and engineers is the committment to combine preclinical knowledge, theoretical computation and clinical applications in the field of Clinical and Experimental Radiation Oncology with a special spotlight on Radiotherapy research.

The IRM is closely associated with the Department of Radiation Oncology and Radiotherapy at the Klinikum rechts der Isar (TU München) as well as the German Consortium for Translational Cancer Research (DKTK) at its partner location in Munich.

The Institute of Radiation Medicine (IRM) at Helmholtz Munich covers all aspects of modern radiation research and focuses on translational issues and clinical applications.

The focus of our highly interdisciplinary team of physicists, biologists, medical doctors and engineers is the committment to combine preclinical knowledge, theoretical computation and clinical applications in the field of Clinical and Experimental Radiation Oncology with a special spotlight on Radiotherapy research.

The IRM is closely associated with the Department of Radiation Oncology and Radiotherapy at the Klinikum rechts der Isar (TU München) as well as the German Consortium for Translational Cancer Research (DKTK) at its partner location in Munich.

Research Groups

Helmholtz Munich | © Raulefs
Combs Group

Personalized RadioOncology

Radiotherapy is an important treatment modality for cancer patients. About 40-50% of all cancer patients are treated with radiotherapy. We are investigating therapy response and aiming to identify biomarkers for adjusting the appropriate irradiation strategy, including application of the proper radiation dose and potential occurrence of adverse side effect. This personalized radiotherapy concept will guide future patient stratification.

© Helmholtz Munich I Schmid
Schmid Group

Radiobiology

Our radiobiology research group investigates the use of novel radiation modalities for improving radiation therapy. Spatial fractionated radiotherapy include Microbeam Radiation Therapy (MRT) and Minibeam Radiation Therapy (MBRT) - two innovative, but still preclinical concepts in radiation therapy. FLASH radiotherapy is a novel technique, involving treatment of tumors at ultra-high dose rates, which reduced the damage to healthy tissue surrounding the tumor. Our main interest is the understanding of the underlying biomedical mechanisms of spatially fractionated and high dose rate (“FLASH”) radiation therapy. The final aim of our research is the translation of these highly innovative techniques into clinical application.

Helmholtz Munich I © Petrich
Bartzsch Group

Experimental Medical Physics

How can we reduce the toxicity of radiation therapy? This question is our driving motivation in the Experimental Medical Physics team. We investigate the next generation radiation oncology modalities that reduce side effects. Our current focus is spatially fractionated and high dose rate (“FLASH”) radiation therapy. We develop and test new radiotherapy equipment, such as an innovative x-ray source, model radiobiological and radiochemical effects with mathematical tools, and simulate and plan treatments with novel, experimental strategies on clinical data. The aim of our interdisciplinary team is the translation of promising research results into clinical application.

Helmholtz Munich I © Peeken
Peeken Group

Artificial Intelligence and Radiomics in Radiation Oncology

Medical imaging plays an essential role at multiple steps in the workflow of Radiation Oncology. In our group, we are investigating the value of artificial intelligence-based medical image analysis for non-invasive tumor characterization, better prognostic assessment, improved tumor detection, and automated treatment planning. This way we aim for improved personalization of cancer care.

Helmholtz Munich I ©Dobiasch
Dobiasch Group

Personalized Radiooncology of Pancreatic Cancer

Pancreatic cancer is one of the most aggressive and lethal human tumors. Therefore, experimental stratification of radiation response and combination with targeted therapies are investigated in preclinical pancreatic cancer models within the framework of translational research. Different in vitro approaches (patient-derived organoids, murine, and human cell lines), as well as innovative high-precision irradiation concepts in advanced tumor mouse models, are established. The major aim is the generation of novel treatment options for pancreatic cancer patients to realize a true personalized medicine and improve clinical outcome.

Our Scientists at Radiation Medicine

Dr. sc. hum. Kerstin A. Eitz

Group Leader Medical Informatics

Dr. Daniela Schilling

Scientific Manager

Prof. Dr. Thomas Schmid

Group Leader Radiobiology Deputy Director View profile

Prof. Dr. Jan Wilkens

Group Leader Medical Physics

Dr. Sophie Dobiasch

Junior Group Leader Personalized Radiooncology of pancreatic cancer View profile

Dr. Katarina Ilicic

Scientist

PD Dr. Stefan Bartzsch

Group Leader Experimental Medical Physics View profile

Dr. Susanne Raulefs

Scientific Manager

Sandra Bicher

PhD student

Johanna Winter

PhD student

Mai Nguyen

Student

PD Dr. Jan C. Peeken

Group Leader Artificial Intelligence and Radiomics in Radiation Oncology View profile

Dr. Kerstin Hürkamp

Scientist

Rainer Lindner

Technical Assistant

Prof. Dr. Werner Rühm

Group Leader Medical and Environmental Dosimetry

Dipl. Phys. Vladimir Mares

Deputy Group Leader Medical and Environmental Dosimetry

Tomasz Maczka

Scientist and IT-Developer

Dr. Nina Petoussi-Henß

Scientist

Dipl. Math. Maria Zankl

Scientist

Dr. Weibo Li

Group Leader Optimization of Radiation Applications in Medicine

Shamil Samanta Galvez Febles

PhD student

Monika Keusch

Team Assistant

Dr. Oleg Tischenko

Scientist

Lena Katzdobler

PhD student

Dr. Jan Christian Kaiser

Group Leader Integrative Modelling

Dr. Clemens Woda

Deputy Group Leader Integrative Modelling

Dr. Noemi Castelletti

Guest Scientist

Tanja Smith

Team Assistant

Dr. Markus Eidemüller

Group Leader Radiation Risk

Dr. Pavel Kundrát

Guest Scientist

Dr.-Ing. Janine Becker

Deputy Group Leader Radiation Risk, Scientist

Tanja Smith

Fremdsprachensekretärin

Dr. Marina Santiago Franco

Scientist

Mabroor Ahmed

PhD student

Dr. Alexander Ulanowski

Scientist, currently on secondment at IAEA

Jessica Stolz

PhD Student

Paula Schwalk

Student

Christian Petrich

PhD student

Alexander Baikalov

PhD Student

Dr. med. Dr. rer. nat. Kim Melanie Kraus

Guest Scientist

Aleksandra Colic

PhD Student

Daniel Friedrich

Student

Dr. Mariaelvy Bianchini

Scientist

Neam Halat

Student

Narayani Subramanian

Student

Felix Kähler

Student

Sethukrishna Prajeesh

Student

Elif Kara

PhD student

Anton Dimroth

Guest Scientist

Publications of Our Institute

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Networks and Affiliations

Contact

Dr. Susanne Raulefs

Scientific Manager