Bioengineering Center

A research team from Helmholtz Munich and the Technical University of Munich has developed an advanced delivery system that transports gene-editing tools based on the CRISPR/Cas9 gene-editing system into living cells with significantly greater…

Helmholtz Munich researchers have introduced a new imaging method that exploits light, sound, and temperature-induced material changes. This approach uncovers a novel contrast mechanism in optoacoustic imaging, driven by tiny temperature-based shifts…

Since March 2024, Vasilis Ntziachristos has been a member of the German National Academy of Sciences Leopoldina. This esteemed recognition stands as one of the highest honors for scientists and is awarded through a thorough multi-stage selection…

Imagine a world where the most intricate networks and processes within whole bodies are visible – down to the level of individual molecules. This is what Ali Ertürk’s pioneering research makes possible, opening up new possibilities for medicine and…

How can we ensure that life-saving drugs or genetic therapies reach their intended target cells without causing harmful side effects? Researchers at Helmholtz Munich, Ludwig-Maximilians-Universität (LMU) and Technical University Munich (TUM) have…

Researchers from Helmholtz Munich and Ludwig-Maximilians-Universität (LMU) have identified a mechanism that may explain the neurological symptoms of Long COVID. The study shows that the SARS-CoV-2 spike protein remains in the brain’s protective…

Interview with Prof. Matthias Tschöp about health research and prevention with cutting-edge tools.

Optoacoustic imaging is transforming biological research by enabling high-resolution imaging at depths beyond traditional optical microscopy. Already applied in clinical settings, this technique now requires more effective optoacoustic labels for use…

The research of Prof. Dr. Vasilis Ntziachristos and his team leads to novel, groundbreaking medical imaging tools. Their non-invasive technologies unveil crucial health and disease details that can empower doctors to identify and address diseases at…

Researchers at Helmholtz Munich and the LMU University Hospital Munich introduce DELiVR, offering a new AI-based approach to the complex task of brain cell mapping. The deep learning tool democratizes advanced neuroscience by eliminating the need for…

Scientists have created a non-invasive technology for measuring glucose levels in blood.

Changes in small blood vessels are a common consequence of diabetes development. Researchers at Helmholtz Munich and the Technical University of Munich (TUM) have now developed a method that can be used to measure these microvascular changes in the…

Sporadic Parkinson's Disease (sPD) is a progressive neurodegenerative disorder influenced by both genetic and environmental factors. While mitochondrial dysfunction contributes to this condition, its role across disease progression remains unclear.…

Researchers at Helmholtz Munich and the Technical University of Munich have made significant progress in advancing high-resolution optoacoustic imaging for clinical use. Their innovative deep-learning framework, known as DeepMB, holds great promise…

Alzheimer's, stroke, multiple sclerosis and other neurological diseases cause severe damage due to neuroinflammation mediated by immune cells. Managing this inflammation poses a significant medical challenge because the brain is protected by the…

Researchers developed a new method called wildDISCO that uses standard antibodies to map the entire body of an animal using fluorescent markers. This revolutionary technique provides detailed 3D maps of structures, shedding new light on complex…

Genetically encoded nano-barcodes

How do the nerve cells in our brain communicate with each other? What processes take place when T cells render cancer cells harmless? Details of the mechanisms at the cellular level remain hidden from view. Now,…

How can the clinical translation of research findings be accelerated to improve human health? What role does bioengineering play in driving the development of medicine and biology solutions? Matthias Tschöp, CEO at Helmholtz Munich and Alexander von…

The renal phosphate wasting disease X-linked hypophosphatemia (XLH) is a rare metabolic disorder of the bones associated with severe renal phosphate loss. The first symptoms of the genetic defect appear in childhood and adolescence and can…

A clinical study confirms the success of a novel technology developed by Helmholtz Munich and the Technical University of Munich (TUM) for the evaluation of the treatment of psoriasis. With the new method, doctors can look deeper into the skin of…

Biomedical imaging is the window through which we can look into organisms. It allows us to see cells, their behavior and localization that would otherwise be hidden. Tracking very few cells over time without damaging them is a key challenge in health…

Researchers at Helmholtz Zentrum München and the Technical University of Munich (TUM) have developed the world’s smallest ultrasound detector. It is based on miniaturized photonic circuits on top of a silicon chip. With a size 100 times smaller than…