All Publications since 2000
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Einer, C. ; Munk, D.E. ; Park, E. ; Akdogan, B. ; Nagel, J. ; Lichtmannegger, J. ; Eberhagen, C. ; Rieder, T. ; Vendelbo, M.H. ; Michalke, B. ; Wimmer, R. ; Blutke, A. ; Feuchtinger, A. ; Dershwitz, P. ; DiSpirito, A.M. ; Islam, T. ; Castro, R.E. ; Min, B.K. ; Kim, T.W. ; Choi, S. ; Kim, D. ; Jung, C. ; Lee, H. ; Park, D. ; Im, W. ; Eun, S.Y. ; Cho, Y.H. ; Semrau, J.D. ; Rodrigues, C.M.P. ; Hohenester, S. ; Damgaard Sandahl, T. ; DiSpirito, A.A. ; Zischka, H.
ARBM101 (Methanobactin SB2) drains excess liver copper via biliary excretion in Wilson's disease rats.Amador, S. ; Beuschlein, F. ; Chauhan, V.P. ; Favier, J. ; Gil, D. ; Greenwood, P. ; de Krijger, R.R. ; Kroiss, M. ; Ortuño-Miquel, S. ; Patocs, A. ; Stell, A. ; Walch, A.K.
Deep learning approaches applied to image classification of renal tumors: A systematic review.Liu, N. ; Gujrati, V. ; Fuenzalida Werner, J.P. ; Mishra, K. ; Anzenhofer,P. ; Stiel, A.-C. ; Mettenleiter, G. ; Feuchtinger, A. ; Walch, A.K. ; Ntziachristos, V.
Bacterial outer membrane vesicles as cationic dye carriers for optoacoustics-guided phototherapy of cancer.Skerniskyte, J. ; Mulet, C. ; André, A.C. ; Anderson, M.C. ; Injarabian, L. ; Buck, A. ; Prade, V.M. ; Sansonetti, P.J. ; Reibel-Foisset, S. ; Walch, A.K. ; Lebel, M. ; Lykkesfeldt, J. ; Marteyn, B.S.
Ascorbate deficiency increases progression of shigellosis in guinea pigs and mice infection models.Wang, J. ; Sun, N. ; Kunzke, T. ; Shen, J. ; Zens, P. ; Prade, V.M. ; Feuchtinger, A. ; Berezowska, S. ; Walch, A.K.
Spatial metabolomics identifies distinct tumor-specific and stroma-specific subtypes in patients with lung squamous cell carcinoma.Han, L. ; Haefner, V. ; Yu, Y. ; Han, B. ; Ren, H. ; Irmler, M. ; Beckers, J. ; Liu, Q. ; Feuchtinger, A. ; Yildirim, A.Ö. ; Adler, H. ; Stöger, T.
Nanoparticle-exposure-triggered virus reactivation induces lung emphysema in mice.Sigle, M. ; Rohlfing, A.K. ; Kenny, M. ; Scheuermann, S. ; Sun, N. ; Graeßner, U. ; Haug, V. ; Sudmann, J. ; Seitz, C.M. ; Heinzmann, D. ; Schenke-Layland, K. ; Maguire, P.B. ; Walch, A. ; Marzi, J. ; Gawaz, M.P.
Translating genomic tools to Raman spectroscopy analysis enables high-dimensional tissue characterization on molecular resolution.Rosowski, S. ; Remmert, C. ; Marder, M. ; Akishiba, M. ; Bushe, J. ; Feuchtinger, A. ; Platen, A. ; Ussar, S. ; Theis, F.J. ; Wiedenmann, S. ; Meier, M.
Single-cell characterization of neovascularization using hiPSC-derived endothelial cells in a 3D microenvironment.Gong, S. ; Sun, N. ; Meyer, L.S. ; Tetti, M. ; Koupourtidou, C. ; Krebs, S. ; Masserdotti, G. ; Blum, H. ; Rainey, W.E. ; Reincke, M. ; Walch, A.K. ; Williams, T.A.
Primary aldosteronism: Spatial multi-omics mapping of genotype-dependent heterogeneity and tumor expansion of aldosterone-producing adenomas.Shen, J. ; Sun, N. ; Wang, J. ; Zens, P. ; Kunzke, T. ; Buck, A. ; Prade, V.M. ; Wang, Q. ; Feuchtinger, A. ; Hu, R. ; Berezowska, S. ; Walch, A.K.
Patterns of carbon-bound exogenous compounds impact disease pathophysiology in lung cancer subtypes in different ways.Wang, Q. ; Sun, N. ; Meixner, R. ; Le Gleut, R. ; Kunzke, T. ; Feuchtinger, A. ; Wang, J. ; Shen, J. ; Kircher, S. ; Dischinger, U. ; Weigand, I. ; Beuschlein, F. ; Fassnacht, M. ; Kroiss, M. ; Walch, A.K.
Metabolic heterogeneity in adrenocortical carcinoma impacts patient outcomes.Klontzas, M.E. ; Koltsakis, E. ; Kalarakis, G. ; Trpkov, K. ; Papathomas, T. ; Sun, N. ; Walch, A.K. ; Karantanas, A.H. ; Tzortzakakis, A.
A pilot radiometabolomics integration study for the characterization of renal oncocytic neoplasia.Langenmayer, M.C. ; Luelf-Averhoff, A.T. ; Marr, L. ; Jany, S. ; Freudenstein, A. ; Adam-Neumair, S. ; Tscherne, A. ; Fux, R. ; Rojas, J.J. ; Blutke, A. ; Sutter, G. ; Volz, A.
Newly designed poxviral promoters to improve immunogenicity and efficacy of MVA-NP candidate vaccines against lethal influenza virus infection in mice.Mateska, I. ; Witt, A. ; Hagag, E. ; Sinha, A. ; Yilmaz, C. ; Thanou, E. ; Sun, N. ; Kolliniati, O. ; Patschin, M. ; Abdelmegeed, H. ; Henneicke, H. ; Kanczkowski, W. ; Wielockx, B. ; Tsatsanis, C. ; Dahl, A. ; Walch, A.K. ; Li, K.W. ; Peitzsch, M. ; Chavakis, T. ; Alexaki, V.I.
Succinate mediates inflammation-induced adrenocortical dysfunction.Esser, K. ; Cheng, X. ; Wettengel, J.M. ; Lucifora, J. ; Hansen-Palmus, L. ; Austen, K. ; Roca Suarez, A.A. ; Heintz, S. ; Testoni, B. ; Nebioglu, F. ; Pham, M.T. ; Yang, S. ; Zernecke, A. ; Wohlleber, D. ; Ringelhan, M. ; Broxtermann, M. ; Hartmann, D. ; Hüser, N. ; Mergner, J. ; Pichlmair, A. ; Thasler, W.E. ; Heikenwälder, M. ; Gasteiger, G. ; Blutke, A. ; Walch, A.K. ; Knolle, P.A. ; Bartenschlager, R. ; Protzer, U.
Hepatitis B virus targets lipid transport pathways to infect hepatocytes.Sigmund, F. ; Berezin, O. ; Beliakova, S. ; Magerl, B. ; Drawitsch, M. ; Piovesan, A. ; Gonçalves, F. ; Bodea, S.V. ; Winkler, S. ; Bousraou, Z. ; Grosshauser, M. ; Samara, E. ; Pujol-Martí, J. ; Schädler, S. ; So, C. ; Irsen, S. ; Walch, A.K. ; Kofler, F. ; Piraud, M. ; Kornfeld, J. ; Briggman, K. ; Westmeyer, G.G.
Genetically encoded barcodes for correlative volume electron microscopy.Sachs, S. ; Götz, A. ; Finan, B. ; Feuchtinger, A. ; DiMarchi, R.D. ; Döring, Y. ; Weber, C. ; Tschöp, M.H. ; Müller, T.D. ; Hofmann, S.M.
GIP receptor agonism improves dyslipidemia and atherosclerosis independently of body weight loss in preclinical mouse model for cardio-metabolic disease.Alfaro, A.J. ; Dittner, C. ; Becker, J. ; Loft, A. ; Mhamane, A. ; Maida, A. ; Georgiadi, A. ; Tsokanos, F.-F. ; Klepac, K. ; Molocea, C.-E. ; El-Merahbi, R. ; Motzler, K. ; Geppert, J. ; Karikari, R.A. ; Szendrödi, J. ; Feuchtinger, A. ; Hofmann, S.M. ; Karaca, S. ; Urlaub, H. ; Berriel Diaz, M. ; Melchior, F. ; Herzig, S.
Fasting-sensitive SUMO-switch on Prox1 controls hepatic cholesterol metabolism.Pisula, J.I. ; Datta, R.R. ; Valdez, L.B. ; Avemarg, J.R. ; Jung, J.O. ; Plum, P. ; Löser, H. ; Lohneis, P. ; Meuschke, M. ; Dos Santos, D.P. ; Gebauer, F. ; Quaas, A. ; Walch, A.K. ; Bruns, C.J. ; Lawonn, K. ; Popp, F.C. ; Bozek, K.
Predicting the HER2 status in oesophageal cancer from tissue microarrays using convolutional neural networks.Murakami, M. ; Sun, N. ; Li, F. ; Feuchtinger, A. ; Gomez-Sanchez, C. ; Fassnacht, M. ; Reincke, M. ; Bancos, I. ; Walch, A.K. ; Kroiss, M. ; Beuschlein, F.
In situ metabolomics of cortisol-producing adenomas.Erlmeier, F. ; Sun, N. ; Shen, J. ; Feuchtinger, A. ; Buck, A. ; Prade, V.M. ; Kunzke, T. ; Schraml, P. ; Moch, H. ; Autenrieth, M. ; Weichert, W. ; Hartmann, A. ; Walch, A.K.
MALDI mass spectrometry imaging-Diagnostic pathways and metabolites for renal tumor entities.Buck, A. ; Prade, V.M. ; Kunzke, T. ; Erben, R.G. ; Walch, A.K.
Spatial metabolomics reveals upregulation of several pyrophosphate-producing pathways in cortical bone of Hyp mice.Klein-Rodewald, T. ; Micklich, K. ; Sanz-Moreno, A. ; Tost, M. ; Calzada-Wack, J. ; Adler, T. ; Klaften, M. ; Sabrautzki, S. ; Aigner, B. ; Kraiger, M. ; Gailus-Durner, V. ; Fuchs, H. ; German Mouse Clinic Consortium (Aguilar-Pimentel, J.A. ; Becker, L. ; Garrett, L. ; Hölter, S.M. ; Prehn, C. ; Rácz, I. ; Rozman, J. ; Puk, O. ; Schrewe, A. ; Adamski, J. ; Esposito, I. ; Wurst, W. ; Stoeger, C.) ; Gründer, A. ; Pahl, H. ; Wolf, E. ; Hrabě de Angelis, M. ; Rathkolb, B.
New C3H KitN824K/WT cancer mouse model develops late-onset malignant mammary tumors with high penetrance.Koch, J. ; Schober, S.J. ; Hindupur, S.V. ; Klein, F.G. ; Mantwill, K. ; Ehrenfeld, M. ; Schillinger, U. ; Hohnecker, T. ; Qi, P. ; Steiger, K. ; Aichler, M. ; Gschwend, J.E. ; Nawroth, R. ; Holm, P.S.
Targeting the Retinoblastoma/E2F repressive complex by CDK4/6 inhibitors amplifies oncolytic potency of an oncolytic adenovirus.Maity-Kumar, G. ; Ständer, L. ; de Angelis, M. ; Lee, S. ; Molenaar, A. ; Becker, L. ; Garrett, L. ; Amarie, O.V. ; Hölter, S.M. ; Wurst, W. ; Fuchs, H. ; Feuchtinger, A. ; Gailus-Durner, V. ; García-Cáceres, C. ; Othman, A.E. ; Brockmann, C. ; Schöffling, V.I. ; Beiser, K. ; Krude, H. ; Mroz, P.A. ; Hofmann, S.M. ; Tuckermann, J. ; DiMarchi, R.D. ; Hrabě de Angelis, M. ; Tschöp, M.H. ; Pfluger, P.T. ; Müller, T.D.
Validation of Mct8/Oatp1c1 dKO mice as a model organism for the Allan-Herndon-Dudley Syndrome.Ackermann, M. ; Kamp, J.C. ; Werlein, C. ; Walsh, C.L. ; Stark, H. ; Prade, V.M. ; Surabattula, R. ; Wagner, W.L. ; Disney, C. ; Bodey, A.J. ; Illig, T. ; Leeming, D.J. ; Karsdal, M.A. ; Tzankov, A. ; Boor, P. ; Kühnel, M.P. ; Länger, F.P. ; Verleden, S.E. ; Kvasnicka, H.M. ; Kreipe, H.H. ; Haverich, A. ; Black, S.M. ; Walch, A. ; Tafforeau, P. ; Lee, P.D. ; Hoeper, M.M. ; Welte, T. ; Seeliger, B. ; David, S.P. ; Schuppan, D. ; Mentzer, S.J. ; Jonigk, D.D.
The fatal trajectory of pulmonary COVID-19 is driven by lobular ischemia and fibrotic remodelling.Lombardo, E. ; Hess J. ; Kurz, C. ; Riboldi, M. ; Marschner, S. ; Baumeister, P. ; Lauber, K. ; Pflugradt, U. ; Walch, A.K. ; Canis, M. ; Klauschen, F. ; Zitzelsberger, H. ; Belka, C. ; Landry, G. ; Unger, K.
DeepClassPathway: Molecular pathway aware classification using explainable deep learning.Hess J. ; Unger, K. ; Maihoefer, C. ; Schuettrumpf, L. ; Weber, P. ; Marschner, S. ; Wintergerst, L. ; Pflugradt, U. ; Baumeister, P. ; Walch, A.K. ; Woischke, C. ; Kirchner, T. ; Werner, M. ; Soerensen, K. ; Baumann, M. ; Tinhofer, I. ; Combs, S.E. ; Debus, J. ; Schaefer, H. ; Krause, M. ; Linge, A. ; von der Gruen, J. ; Stuschke, M. ; Zips, D. ; Canis, M. ; Lauber, K. ; Ganswindt, U. ; Henke, M. ; Zitzelsberger, H. ; Belka, C.
Integration of p16/HPV DNA status with a 24-miRNA-defined molecular phenotype improves clinically relevant stratification of head and neck cancer patients.Kreutzer, L. ; Weber, P. ; Heider, T. ; Heikenwaelder, M. ; Riedl, T. ; Baumeister, P. ; Klauschen, F. ; Belka, C. ; Walch, A.K. ; Zitzelsberger, H. ; Hess J. ; Unger, K.
Simultaneous metabolite MALDI-MSI, whole exome and transcriptome analysis from formalin-fixed paraffin-embedded tissue sections.Hui, B. ; Lu, C. ; Li, H. ; Hao, X. ; Liu, H. ; Zhuo, D. ; Wang, Q. ; Li, Z. ; Liu, L. ; Wang, X. ; Gu, Y. ; Tang, W.
Inhibition of APOE potentiates immune checkpoint therapy for cancer.Erlmeier, F. ; Sun, N. ; Shen, J. ; Feuchtinger, A. ; Buck, A. ; Prade, V.M. ; Kunzke, T. ; Schraml, P. ; Moch, H. ; Autenrieth, M. ; Weichert, W. ; Hartmann, A. ; Walch, A.K.
MALDI mass spectrometry imaging—prognostic pathways and metabolites for renal cell carcinomas.Wang, Q. ; Sun, N. ; Kunzke, T. ; Buck, A. ; Shen, J. ; Prade, V.M. ; Stöckl, B. ; Wang, J. ; Feuchtinger, A. ; Walch, A.K.
A simple preparation step to remove excess liquid lipids in white adipose tissue enabling improved detection of metabolites via MALDI-FTICR imaging MS.Ebert, K. ; Haffner, I. ; Zwingenberger, G. ; Keller, S. ; Raimúndez, E. ; Geffers, R. ; Wirtz, R. ; Barbaria, E. ; Hollerieth, V. ; Arnold, R. ; Walch, A.K. ; Hasenauer, J. ; Maier, D. ; Lordick, F. ; Luber, B.
Combining gene expression analysis of gastric cancer cell lines and tumor specimens to identify biomarkers for anti-HER therapies-the role of HAS2, SHB and HBEGF.Ravi, V.M. ; Will, P. ; Kueckelhaus, J. ; Sun, N. ; Joseph, K. ; Salié, H. ; Vollmer, L. ; Kuliesiute, U. ; von Ehr, J. ; Benotmane, J.K. ; Neidert, N. ; Follo, M. ; Scherer, F. ; Goeldner, J.M. ; Behringer, S.P. ; Franco, P. ; Khiat, M. ; Zhang, J. ; Hofmann, U.G. ; Fung, C. ; Ricklefs, F.L. ; Lamszus, K. ; Boerries, M. ; Ku, M.C. ; Beck, J. ; Sankowski, R. ; Schwabenland, M. ; Prinz, M. ; Schüller, U. ; Killmer, S. ; Bengsch, B. ; Walch, A.K. ; Delev, D. ; Schnell, O. ; Heiland, D.H.
Spatially resolved multi-omics deciphers bidirectional tumor-host interdependence in glioblastoma.Tang, W. ; Zhou, Y. ; Zhao, H. ; Sun, G. ; Rong, D. ; Li, Z. ; Hu, M. ; Han, L.F. ; He, X. ; Zhao, S. ; Chen, X. ; Yuan, H. ; Chen, S. ; Wang, Q. ; Gu, J. ; Wang, X. ; Song, J.
A 3D multi-modal intelligent intervention system using electromagnetic navigation for real-time positioning and ultrasound images: A prospective randomized controlled trial.Shen, J. ; Sun, N. ; Zens, P. ; Kunzke, T. ; Buck, A. ; Prade, V.M. ; Wang, J. ; Wang, Q. ; Hu, R. ; Feuchtinger, A. ; Berezowska, S. ; Walch, A.K.
Spatial metabolomics for evaluating response to neoadjuvant therapy in non-small cell lung cancer patients.Prade, V.M. ; Sun, N. ; Shen, J. ; Feuchtinger, A. ; Kunzke, T. ; Buck, A. ; Schraml, P. ; Moch, H. ; Schwamborn, K. ; Autenrieth, M. ; Gschwend, J.E. ; Erlmeier, F. ; Hartmann, A. ; Walch, A.K.
The synergism of spatial metabolomics and morphometry improves machine learning-based renal tumour subtype classification.Paul, T. ; Ledderose, S. ; Bartsch, H. ; Sun, N. ; Soliman, S. ; Märkl, B. ; Ruf, V. ; Herms, J. ; Stern, M. ; Keppler, O.T. ; Delbridge, C. ; Müller, S. ; Piontek, G. ; Kimoto, Y.S. ; Schreiber, F. ; Williams, T.A. ; Neumann, J. ; Knösel, T. ; Schulz, H. ; Spallek, R. ; Graw, M. ; Kirchner, T. ; Walch, A.K. ; Rudelius, M.
Adrenal tropism of SARS-CoV-2 and adrenal findings in a post-mortem case series of patients with severe fatal COVID-19.Loft, A. ; Schmidt, S.F. ; Caratti, G. ; Stifel, U. ; Havelund, J.F. ; Sekar, R. ; Kwon, Y. ; Sulaj, A. ; Chow, K.K. ; Alfaro, A.J. ; Schwarzmayr, T. ; Rittig, N. ; Svart, M. ; Tsokanos, F.-F. ; Maida, A. ; Blutke, A. ; Feuchtinger, A. ; Møller, N. ; Blüher, M. ; Nawroth, P. ; Szendrödi, J. ; Færgeman, N.J. ; Zeigerer, A. ; Tuckermann, J. ; Herzig, S.
A macrophage-hepatocyte glucocorticoid receptor axis coordinates fasting ketogenesis.Eumorphia Consortium (Hrabě de Angelis, M. ; Wurst, W. ; Abe, K. ; Beckers, J. ; Busch, D.H. ; Dalke, C. ; Gailus-Durner, V. ; Fuchs, H. ; Graw, J. ; Hölter, S.M. ; Kallnik, M. ; Lengger, C. ; Pedersen, V. ; Puk, O. ; Vogt Weisenhorn, D.M. ; Wagner, S.) ; Quintanilla-Fend, L.
EMPReSS: Standardized phenotype screens for functional annotation of the mouse genome (vol 37, pg 1155, 2005).Wang, J. ; Kunzke, T. ; Prade, V.M. ; Shen, J. ; Buck, A. ; Feuchtinger, A. ; Haffner, I. ; Luber, B. ; Liu, D.H.W. ; Langer, R. ; Lordick, F. ; Sun, N. ; Walch, A.K.
Spatial metabolomics identifies distinct tumor-specific subtypes in gastric cancer patients.Sato, S. ; Dyar, K.A. ; Treebak, J.T. ; Jepsen, S.L. ; Ehrlich, A.M. ; Ashcroft, S.P. ; Trost, K. ; Kunzke, T. ; Prade, V.M. ; Small, L. ; Basse, A.L. ; Schönke, M. ; Chen, S. ; Samad, M. ; Baldi, P. ; Barrès, R. ; Walch, A.K. ; Moritz, T. ; Holst, J.J. ; Lutter, D. ; Zierath, J.R. ; Sassone-Corsi, P.
Atlas of exercise metabolism reveals time-dependent signatures of metabolic homeostasis.Weber, P. ; Künstner, A. ; Hess J. ; Unger, K. ; Marschner, S. ; Idel, C. ; Ribbat-Idel, J. ; Walz, C. ; Rietzler, S. ; Valeanu, L. ; Herkommer, T. ; Kreutzer, L. ; Klymenko, O. ; Kirchner, T. ; Ganswindt, U. ; Walch, A.K. ; Sterr, M. ; Lickert, H. ; Canis, M. ; Rades, D. ; Perner, S. ; Berriel Diaz, M. ; Herzig, S. ; Wollenberg, B. ; Busch, H. ; Zitzelsberger, H.
Therapy-related transcriptional subtypes in matched primary and recurrent head and neck cancer.Buck, A. ; Prade, V.M. ; Kunzke, T. ; Feuchtinger, A. ; Kröll, D. ; Feith, M. ; Dislich, B. ; Balluff, B. ; Langer, R. ; Walch, A.K.
Metabolic tumor constitution is superior to tumor regression grading for evaluating response to neoadjuvant therapy of esophageal adenocarcinoma patients.Liu, N. ; O'Connor, P. ; Gujrati, V. ; Gorpas, D. ; Glasl, S. ; Blutke, A. ; Walch, A.K. ; Kleigrewe, K. ; Sattler, M. ; Plettenburg, O. ; Ntziachristos, V.
Facile synthesis of a croconaine-based nanoformulation for optoacoustic imaging and photothermal therapy.Li, Z. ; Sun, G. ; Sun, G. ; Cheng, Y. ; Wu, L. ; Wang, Q. ; Lv, C. ; Zhou, Y. ; Xia, Y. ; Tang, W.
Various uses of PD1/PD-L1 inhibitor in oncology: Opportunities and challenges.Sun, N. ; Trajkovic-Arsic, M. ; Li, F. ; Wu, Y. ; Münch, C. ; Kunzke, T. ; Feuchtinger, A. ; Steiger, K. ; Schlitter, A.M. ; Weichert, W. ; Esposito, I. ; Siveke, J.T. ; Walch, A.K.
Native glycan fragments detected by MALDI mass spectrometry imaging are independent prognostic factors in pancreatic ductal adenocarcinoma.Yuan, S. ; Liao, G. ; Zhang, M. ; Zhu, Y. ; Xiao, W. ; Wang, K. ; Li, C. ; Jia, C. ; Sun, N. ; Walch, A.K. ; Gao, D. ; Xu, P. ; Deng, Q. ; Zhang, J. ; Wang, H. ; Hu, R.
Multiomics interrogation into HBV (Hepatitis B virus)-host interaction reveals novel coding potential in human genome, and identifies canonical and non-canonical proteins as host restriction factors against HBV.Zhao, L. ; Chen, F. ; Quitt, O. ; Festag, M. ; Ringelhan, M. ; Wisskirchen, K. ; Festag, J. ; Yakovleva, L. ; Sureau, C. ; Bohne, F. ; Aichler, M. ; Bruss, V. ; Shevtsov, M. ; van de Klundert, M. ; Momburg, F. ; Möhl, B.S. ; Protzer, U.
Hepatitis B virus envelope proteins can serve as therapeutic targets embedded in the host cell plasma membrane.Burkhardt, R. ; Gora, T. ; Fingerle, A.A. ; Sauter, A.P. ; Meurer, F. ; Gassert, F.T. ; Dobiasch, S. ; Schilling, D. ; Feuchtinger, A. ; Walch, A.K. ; Multhoff, G. ; Herzen, J. ; Noel, P.B. ; Rummeny, E.J. ; Combs, S.E. ; Schmid, T.E. ; Pfeiffer, F. ; Wilkens, J.J.
In-vivo X-ray dark-field computed tomography for the detection of radiation-induced lung damage in mice.Kunzke, T. ; Prade, V.M. ; Buck, A. ; Sun, N. ; Feuchtinger, A. ; Matzka, M. ; Fernandez, I.E. ; Wuyts, W.A. ; Ackermann, M. ; Jonigk, D. ; Aichler, M. ; Schmid, R.A. ; Eickelberg, O. ; Berezowska, S. ; Walch, A.K.
Patterns of carbon-bound exogenous compounds in lung cancer patients and association with disease pathophysiology.Kunzke, T. ; Hölzl, F.T. ; Prade, V.M. ; Buck, A. ; Huber, K. ; Feuchtinger, A. ; Ebert, K. ; Zwingenberger, G. ; Geffers, R. ; Hauck, S.M. ; Haffner, I. ; Luber, B. ; Lordick, F. ; Walch, A.K.
Metabolomic therapy response prediction in pretherapeutic tissue biopsies for trastuzumab in patients with HER2-positive advanced gastric cancer.Aliluev, A. ; Tritschler, S. ; Sterr, M. ; Oppenländer, L. ; Hinterdobler, J. ; Greisle, T. ; Irmler, M. ; Beckers, J. ; Sun, N. ; Walch, A.K. ; Stemmer, K. ; Kindt, A. ; Krumsiek, J. ; Tschöp, M.H. ; Luecken, M. ; Theis, F.J. ; Lickert, H. ; Böttcher, A.
Diet-induced alteration of intestinal stem cell function underlies obesity and prediabetes in mice.Huang, S. ; Blutke, A. ; Feuchtinger, A. ; Klemm, U. ; Zachariah Tom, R. ; Hofmann, S.M. ; Stiel, A.C. ; Ntziachristos, V.
Functional multispectral optoacoustic tomography imaging of hepatic steatosis development in mice.Chhabra, N.F. ; Amend, A.-L. ; Bastidas-Ponce, A. ; Sabrautzki, S. ; Tarquis Medina, M. ; Sachs, S. ; Rubey, M. ; Lorenz-Depiereux, B. ; Feuchtinger, A. ; Bakhti, M. ; Lickert, H. ; Przemeck, G.K.H. ; Hrabě de Angelis, M.
A point mutation in the Pdia6 gene results in loss of pancreatic β-cell identity causing overt diabetes.Maier, J.P. ; Kueckelhaus, J. ; Behringer, S.P. ; Garrelfs, N. ; Will, P. ; Sun, N. ; von Ehr, J. ; Goeldner, J.M. ; Pfeifer, D. ; Follo, M. ; Hannibal, L. ; Walch, A.K. ; Hofmann, U.G. ; Beck, J. ; Heiland, D.H. ; Schnell, O.
Inhibition of metabotropic glutamate receptor III facilitates sensitization to alkylating chemotherapeutics in glioblastoma.Loft, A. ; Alfaro, A.J. ; Schmidt, S.F. ; Pedersen, F.B. ; Terkelsen, M.K. ; Puglia, M. ; Chow, K.K. ; Feuchtinger, A. ; Troullinaki, M. ; Maida, A. ; Wolff, G. ; Sakurai, M. ; Berutti, R. ; Ekim Üstünel, B. ; Nawroth, P.P. ; Ravnskjaer, K. ; Diaz, M.B. ; Blagoev, B. ; Herzig, S.
Liver-fibrosis-activated transcriptional networks govern hepatocyte reprogramming and intra-hepatic communication.Murakami, M. ; Sun, N. ; Greunke, C. ; Feuchtinger, A. ; Kircher, S. ; Deutschbein, T. ; Papathomas, T. ; Bechmann, N. ; Wallace, P.W. ; Peitzsch, M. ; Korpershoek, E. ; Friemel, J. ; Gimenez Roqueplo, A.P. ; Robledo, M. ; Timmers, H.J. ; Canu, L. ; Weber, A. ; de Krijger, R.R. ; Fassnacht, M. ; Knösel, T. ; Kirchner, T. ; Reincke, M. ; Walch, A.K. ; Kroiss, M. ; Beuschlein, F.
Mass spectrometry imaging identifies metabolic patterns associated with malignant potential in pheochromocytoma and paraganglioma.Giroud, M. ; Tsokanos, F.-F. ; Caratti, G. ; Kotschi, S. ; Khani, S. ; Jouffe, C. ; Vogl, E.S. ; Irmler, M. ; Glantschnig, C. ; Gil Lozano, M. ; Haß, D. ; Khan, A.A. ; Rios Garcia, M. ; Mattijssen, F. ; Maida, A. ; Tews, D. ; Fischer-Posovszky, P. ; Feuchtinger, A. ; Virtanen, K.A. ; Beckers, J. ; Wabitsch, M. ; Uhlenhaut, N.H. ; Blüher, M. ; Tuckermann, J. ; Scheideler, M. ; Bartelt, A. ; Herzig, S.
HAND2 is a novel obesity-linked adipogenic transcription factor regulated by glucocorticoid signalling.Georgiadi, A. ; Lopez Salazar, V. ; El-Merahbi, R. ; Karikari, R.A. ; Ma, X. ; Mourao, A. ; Klepac, K. ; Bühler, L. ; Alfaro, A.J. ; Kaczmarek, I. ; Linford, A. ; Bosma, M. ; Shilkova, O. ; Ritvos, O. ; Nakamura, N. ; Hirose, S. ; Lassi, M. ; Teperino, R. ; Machado, J. ; Scheideler, M. ; Dietrich, A. ; Geerlof, A. ; Feuchtinger, A. ; Blutke, A. ; Fischer, K. ; Müller, T.D. ; Kessler, K. ; Schöneberg, T. ; Thor, D. ; Hornemann, S. ; Kruse, M. ; Nawroth, P.P. ; Pivovarova-Ramich, O. ; Pfeiffer, A.F.H. ; Sattler, M. ; Blüher, M. ; Herzig, S.
Orphan GPR116 mediates the insulin sensitizing effects of the hepatokine FNDC4 in adipose tissue.Liu, N. ; Gujrati, V. ; Malekzadeh-Najafabadi, J. ; Werner, J.P,F. ; Klemm, U. ; Tang, L. ; Chen, Z. ; Prakash, J. ; Huang, Y. ; Stiel, A.-C. ; Mettenleiter, G. ; Aichler, M. ; Blutke, A. ; Walch, A.K. ; Kleigrewe, K. ; Razansky, D. ; Sattler, M. ; Ntziachristos, V.
Croconaine-based nanoparticles enable efficient optoacoustic imaging of murine brain tumors.Orth, M. ; Albrecht, V. ; Seidl, K. ; Kinzel, L. ; Unger, K. ; Hess J. ; Kreutzer, L. ; Sun, N. ; Stegen, B. ; Nieto, A. ; Maas, J. ; Winssinger, N. ; Friedl, A.A. ; Walch, A.K. ; Belka, C. ; Zitzelsberger, H. ; Niyazi, M. ; Lauber, K.
Inhibition of HSP90 as a strategy to radiosensitize glioblastoma: Targeting the DNA damage response and beyond.Haffner, I. ; Schierle, K. ; Raimúndez, E. ; Geier, B. ; Maier, D. ; Hasenauer, J. ; Luber, B. ; Walch, A.K. ; Kolbe, K. ; Riera Knorrenschild, J. ; Kretzschmar, A. ; Rau, B. ; Fischer von Weikersthal, L. ; Ahlborn, M. ; Siegler, G. ; Fuxius, S. ; Decker, T. ; Wittekind, C. ; Lordick, F.
HER2 expression, test deviations, and their impact on survival in metastatic gastric cancer: Results from the prospective multicenter VARIANZ study.Li, F. ; Gu, J. ; Xin, J. ; Schnelle-Kreis, J. ; Wang, Y. ; Liu, Z. ; Shen, R. ; Michalke, B. ; Abbaszade, G. ; Zimmermann, R.
Characteristics of chemical profile, sources and PAH toxicity of PM2.5 in beijing in autumn-winter transit season with regard to domestic heating, pollution control measures and meteorology.Liu, N. ; O'Connor, P. ; Gujrati, V. ; Gorpas, D. ; Glasl, S. ; Blutke, A. ; Walch, A.K. ; Kleigrewe, K. ; Sattler, M. ; Plettenburg, O. ; Ntziachristos, V.
Facile synthesis of a croconaine-based nanoformulation for optoacoustic imaging and photothermal therapy.Ansarullah ; Jain, C. ; Far, F.F. ; Homberg, S. ; Wißmiller, K. ; von Hahn, F. ; Raducanu, A. ; Schirge, S. ; Sterr, M. ; Bilekova, S. ; Siehler, J. ; Wiener, J. ; Oppenländer, L. ; Morshedi, A. ; Bastidas-Ponce, A. ; Collden, G. ; Irmler, M. ; Beckers, J. ; Feuchtinger, A. ; Grzybek, M. ; Ahlbrecht, C. ; Feederle, R. ; Plettenburg, O. ; Müller, T.D. ; Meier, M. ; Tschöp, M.H. ; Coskun, Ü. ; Lickert, H.
Author Correction: Inceptor counteracts insulin signalling in β-cells to control glycaemia.Stauffer, E. ; Weber, P. ; Heider, T. ; Dalke, C. ; Blutke, A. ; Walch, A.K. ; Burgstaller, G. ; Brix, N. ; Lauber, K. ; Zitzelsberger, H. ; Unger, K. ; Selmansberger, M.
Transcriptomic landscape of radiation-induced murine thyroid proliferative lesions.Yuan, S. ; Liao, G. ; Zhang, M. ; Zhu, Y. ; Wang, K. ; Xiao, W. ; Jia, C. ; Dong, M. ; Sun, N. ; Walch, A.K. ; Xu, P. ; Zhang, J. ; Deng, Q. ; Hu, R.
Translatomic profiling reveals novel self-restricting virus-host interactions during HBV infection.Theobalt, N. ; Hofmann, I. ; Fiedler, S. ; Renner, S. ; Dhom, G. ; Feuchtinger, A. ; Walch, A.K. ; Hrabě de Angelis, M. ; Wolf, E. ; Wanke, R. ; Blutke, A.
Unbiased analysis of obesity related, fat depot specific changes of adipocyte volumes and numbers using light sheet fluorescence microscopy.Ruiz Ojeda, F.J. ; Wang, J. ; Bäcker, T. ; Krueger, M. ; Zamani, S. ; Rosowski, S. ; Gruber, T. ; Onogi, Y. ; Feuchtinger, A. ; Schulz, T.J. ; Fässler, R. ; Müller, T.D. ; García-Cáceres, C. ; Meier, M. ; Blüher, M. ; Ussar, S.
Active integrins regulate white adipose tissue insulin sensitivity and brown fat thermogenesis.Ansarullah ; Jain, C. ; Far, F.F. ; Homberg, S. ; Wissmiller, K. ; Gräfin von Hahn, F. ; Raducanu, A. ; Schirge, S. ; Sterr, M. ; Bilekova, S. ; Siehler, J. ; Wiener, J. ; Oppenländer, L. ; Morshedi, A. ; Bastidas-Ponce, A. ; Collden, G. ; Irmler, M. ; Beckers, J. ; Feuchtinger, A. ; Grzybek, M. ; Ahlbrecht, C. ; Feederle, R. ; Plettenburg, O. ; Müller, T.D. ; Meier, M. ; Tschöp, M.H. ; Coskun, Ü. ; Lickert, H.
Inceptor counteracts insulin signalling in β-cells to control glycaemia.Zhang, Q. ; Delessa, C.T. ; Augustin, R. ; Bakhti, M. ; Collden, G. ; Drucker, D.J. ; Feuchtinger, A. ; García-Cáceres, C. ; Grandl, G. ; Harger, A. ; Herzig, S. ; Hofmann, S.M. ; Holleman, C.L. ; Jastroch, M. ; Keipert, S. ; Kleinert, M. ; Knerr, P.J. ; Kulaj, K. ; Legutko, B. ; Lickert, H. ; Liu, X. ; Luippold, G. ; Lutter, D. ; Malogajski, E. ; Tarquis Medina, M. ; Mowery, S.A. ; Blutke, A. ; Perez-Tilve, D. ; Salinno, C. ; Sehrer, L. ; DiMarchi, R.D. ; Tschöp, M.H. ; Stemmer, K. ; Finan, B. ; Wolfrum, C. ; Müller, T.D.
The glucose-dependent insulinotropic polypeptide (GIP) regulates body weight and food intake via CNS-GIPR signaling.Bühler, L. ; Maida, A. ; Vogl, E.S. ; Georgiadi, A. ; Takacs, A. ; Kluth, O. ; Schürmann, A. ; Feuchtinger, A. ; von Toerne, C. ; Tsokanos, F.-F. ; Klepac, K. ; Wolff, G. ; Sakurai, M. ; Ekim Üstünel, B. ; Nawroth, P.P. ; Herzig, S.
Lipocalin 13 enhances insulin secretion but is dispensable for systemic metabolic control.Schinke, H. ; Heider, T. ; Herkommer, T. ; Simon, F. ; Blancke Soares, A. ; Kranz, G. ; Samaga, D. ; Dajka, L. ; Feuchtinger, A. ; Walch, A.K. ; Valeanu, L. ; Walz, C. ; Kirchner, T. ; Canis, M. ; Baumeister, P. ; Belka, C. ; Maihöfer, C. ; Marschner, S. ; Pflugradt, U. ; Ganswindt, U. ; Hess J. ; Zitzelsberger, H. ; Gires, O.
Digital scoring of EpCAM and slug expression as prognostic markers in head and neck squamous cell carcinomas.Napieralski, R. ; Schricker, G. ; Auer, G. ; Aubele, M. ; Perkins, J. ; Magdolen, V. ; Ulm, K. ; Hamann, M. ; Walch, A.K. ; Weichert, W. ; Kiehle, M. ; Weichert, O.G.
PITX2 DNA-methylation: Predictive versus prognostic value for anthracycline-based chemotherapy in triple-negative breast cancer patients.Karlina, R. ; Lutter, D. ; Miok, V. ; Fischer, D.S. ; Altun, I. ; Schöttl, T. ; Schorpp, K.K. ; Israel, A. ; Cero, C. ; Johnson, J.W. ; Kapser-Fischer, I. ; Böttcher, A. ; Keipert, S. ; Feuchtinger, A. ; Graf, E. ; Strom, T.M. ; Walch, A.K. ; Lickert, H. ; Walzthoeni, T. ; Heinig, M. ; Theis, F.J. ; García-Cáceres, C. ; Cypess, A.M. ; Ussar, S.
Identification and characterization of distinct brown adipocyte subtypes in C57BL/6J mice.Ung, M.-C. ; Garrett, L. ; Dalke, C. ; Leitner, V. ; Dragosa, D. ; Hladik, D ; Neff, F. ; Wagner, F. ; Zitzelsberger, H. ; Miller, G. ; Hrabě de Angelis, M. ; Rößler, U. ; Vogt Weisenhorn, D.M. ; Wurst, W. ; Graw, J. ; Hölter, S.M.
Dose-dependent long-term effects of a single radiation event on behaviour and glial cells.Burkhardt, R. ; Gora, T. ; Fingerle, A.A. ; Sauter, A.P. ; Meurer, F. ; Umkehrer, S. ; Von Teuffenbach, M. ; Kampfer, S. ; Schilling, D. ; Feuchtinger, A. ; Walch, A.K. ; Rummeny, E. ; Combs, S.E. ; Schmid, T.E. ; Pfeiffer, F. ; Wilkens, J.J. ; Herzen, J.
Early detection of radiation-induced lung damage with X-ray dark-field radiography in mice.Sammer, M. ; Dombrowsky, A. ; Schauer, J. ; Oleksenko, K. ; Bicher, S. ; Schwarz, B. ; Rudigkeit, S. ; Matejka, N. ; Reindl, J. ; Bartzsch, S. ; Blutke, A. ; Feuchtinger, A. ; Combs, S.E. ; Dollinger, G. ; Schmid, T.E.
Normal tissue response of combined temporal and spatial fractionation in proton minibeam radiation therapy.Fiedler, S. ; Wünnemann, H. ; Hofmann, I. ; Theobalt, N. ; Feuchtinger, A. ; Walch, A.K. ; Schwaiger, J. ; Wanke, R. ; Blutke, A.
A practical guide to unbiased quantitative morphological analyses of the gills of rainbow trout (Oncorhynchus mykiss) in ecotoxicological studies.Wang, Q. ; Yang, L. ; Fan, Y. ; Tang, W. ; Sun, H. ; Xu, Z. ; Zhou, J. ; Zhang, Y. ; Zhu, B. ; Cao, X.
Circ-ZDHHC5 accelerates esophageal squamous cell carcinoma progression in vitro via miR-217/ZEB1 axis.Papathomas, T. ; Tzortzakakis, A. ; Sun, N. ; Erlmeier, F. ; Feuchtinger, A. ; Trpkov, K. ; Bazarova, A. ; Arvanitis, A. ; Wang, W. ; Bozoky, B. ; Kokaraki, G. ; Axelsson, R. ; Walch, A.K.
In situ metabolomics expands the spectrum of renal tumours positive on 99mTc-sestamibi single photon emission computed tomography/computed tomography examination.Vohra, T. ; Kemter, E. ; Sun, N. ; Dobenecker, B. ; Hinrichs, A. ; Burrello, J. ; Gomez-Sanchez, E.P. ; Gomez-Sanchez, C.E. ; Wang, J. ; Kinker, I.S. ; Teupser, D. ; Fischer, K. ; Schnieke, A. ; Peitzsch, M. ; Eisenhofer, G. ; Walch, A.K. ; Reincke, M. ; Wolf, E. ; Williams, T.A.
Effect of dietary sodium modulation on pig adrenal steroidogenesis and transcriptome profiles.Wu, F. ; Cheng, Y. ; Wu, L. ; Zhang, W. ; Zheng, W. ; Wang, Q. ; Cao, H. ; Pan, X. ; Tang, W.
Emerging landscapes of tumor immunity and metabolism.Zettler, S. ; Renner, S. ; Kemter, E. ; Hinrichs, A. ; Klymiuk, N. ; Backman, M. ; Riedel, E.O. ; Mueller, C. ; Streckel, E. ; Braun-Reichhart, C. ; Martins, A.S. ; Kurome, M. ; Keßler, B. ; Zakhartchenko, V. ; Flenkenthaler, F. ; Arnold, G.J. ; Fröhlich, T. ; Blum, H. ; Blutke, A. ; Wanke, R. ; Wolf, E.
A decade of experience with genetically tailored pig models for diabetes and metabolic research.Chhabra, N.F. ; Amarie, O.V. ; Wu, M. ; Amend, A.-L. ; Rubey, M. ; Gradinger, D. ; Irmler, M. ; Beckers, J. ; Rathkolb, B. ; Wolf, E. ; Feuchtinger, A. ; Huypens, P. ; Teperino, R. ; Rozman, J. ; Przemeck, G.K.H. ; Hrabě de Angelis, M.
PAX6 mutation alters circadian rhythm and beta cell function in mice without affecting glucose tolerance.Azimzadeh, O. ; Azizova, T. ; Merl-Pham, J. ; Blutke, A. ; Moseeva, M. ; Zubkova, O. ; Anastasov, N. ; Feuchtinger, A. ; Hauck, S.M. ; Atkinson, M.J. ; Tapio, S.
Chronic occupational exposure to ionizing radiation induces alterations in the structure and metabolism of the heart: A proteomic analysis of human formalin-fixed paraffin-embedded (FFPE) cardiac tissue.Neef, S.K. ; Winter, S. ; Hofmann, U. ; Mürdter, T.E. ; Schaeffeler, E. ; Horn, H. ; Buck, A. ; Walch, A.K. ; Hennenlotter, J. ; Ott, G. ; Fend, F. ; Bedke, J. ; Schwab, M. ; Haag, M.
Optimized protocol for metabolomic and lipidomic profiling in formalin-fixed paraffin-embedded kidney tissue by LC-MS.Blutke, A. ; Sun, N. ; Xu, Z. ; Buck, A. ; Harrison, L. ; Schriever, S.C. ; Pfluger, P.T. ; Wiles, D. ; Kunzke, T. ; Huber, K. ; Schlegel, J. ; Aichler, M. ; Feuchtinger, A. ; Matiasek, K. ; Hauck, S.M. ; Walch, A.K.
Light sheet fluorescence microscopy guided MALDI-imaging mass spectrometry of cleared tissue samples.Geng, X. ; Babayeva, L. ; Walch, A.K. ; Aubele, M. ; Gross, E. ; Kiechle, M. ; Bronger, H. ; Dreyer, T. ; Magdolen, V. ; Dorn, J.
High levels of KLK7 protein expression are related to a favorable prognosis in triple-negative breast cancer patients.Turcu, A.F. ; Walch, A.K.
A multi-test strategy for adrenal tumours.Ščupáková, K. ; Dewez, F. ; Walch, A.K. ; Heeren, R.M.A. ; Balluff, B.
Morphometric cell classification for single-Cell MALDI-mass spectrometry imaging.Fischer, A. ; Koopmans, T. ; Ramesh, P. ; Christ, S. ; Strunz, M. ; Wannemacher, J. ; Aichler, M. ; Feuchtinger, A. ; Walch, A.K. ; Ansari, M. ; Theis, F.J. ; Schorpp, K.K. ; Hadian, K. ; Neumann, P.A. ; Schiller, H. B. ; Rinkevich, Y.
Post-surgical adhesions are triggered by calcium-dependent membrane bridges between mesothelial surfaces.Niu, Z. ; Sarkar, R. ; Aichler, M. ; Wester, H. ; Yousefi, B.H. ; Reif, B.
Mapping of the binding interface of PET tracer molecules and Alzheimer Disease Aβ fibrils using MAS solid-state NMR spectroscopy.Li, F. ; Feuchtinger, A. ; Walch, A.K. ; Sun, N.
In situ metabolite mass spectrometry imaging: New insights into the adrenal gland.Bergmann, N. ; Delbridge, C. ; Gempt, J. ; Feuchtinger, A. ; Walch, A.K. ; Schirmer, L. ; Bunk, W. ; Aschenbrenner, T. ; Liesche-Starnecker, F. ; Schlegel, J.
The intratumoral heterogeneity reflects the intertumoral subtypes of glioblastoma multiforme: A regional immunohistochemistry analysis.Hedegger, K. ; Algül, H. ; Lesina, M. ; Blutke, A. ; Schmid, R.M. ; Schneider, M.R. ; Dahlhoff, M.
Unraveling ERBB network dynamics upon betacellulin signaling in pancreatic ductal adenocarcinoma in mice.Prade, V.M. ; Kunzke, T. ; Feuchtinger, A. ; Rohm, M. ; Luber, B. ; Lordick, F. ; Buck, A. ; Walch, A.K.
De novo discovery of metabolic heterogeneity with immunophenotype-guided imaging mass spectrometry.Khaloian, S. ; Rath, E. ; Hammoudi, N. ; Gleisinger, E. ; Blutke, A. ; Giesbertz, P. ; Berger, E. ; Metwaly, A. ; Waldschmitt, N. ; Allez, M. ; Haller, D.
Mitochondrial impairment drives intestinal stem cell transition into dysfunctional Paneth cells predicting Crohn's disease recurrence.Huang, Y.M. ; Hong, X.Z. ; Shen, J. ; Huang, Y. ; Zhao, H.L.
China's oldest coronavirus survivors.Weigand, I. ; Schreiner, J. ; Röhrig, F. ; Sun, N. ; Landwehr, L.S. ; Urlaub, H. ; Kendl, S. ; Kiseljak-Vassiliades, K. ; Wierman, M.E. ; Angeli, J.P.F. ; Walch, A.K. ; Sbiera, S. ; Fassnacht, M. ; Kroiss, M.
Active steroid hormone synthesis renders adrenocortical cells highly susceptible to type II ferroptosis induction.Sun, N. ; Meyer, L.S. ; Feuchtinger, A. ; Kunzke, T. ; Knösel, T. ; Reincke, M. ; Walch, A.K. ; Williams, T.A.
Mass spectrometry imaging establishes 2 distinct metabolic phenotypes of aldosterone-producing cell clusters in primary aldosteronism.Riedel, E.O. ; Hinrichs, A. ; Kemter, E. ; Dahlhoff, M. ; Backman, M. ; Rathkolb, B. ; Prehn, C. ; Adamski, J. ; Renner, S. ; Blutke, A. ; Hrabě de Angelis, M. ; Bidlingmaier, M. ; Schopohl, J. ; Arnold, G.J. ; Fröhlich, T. ; Wolf, E.
Functional changes of the liver in the absence of growth hormone (GH) action - Proteomic and metabolomic insights from a GH receptor deficient pig model.Lohöfer, F. ; Buchholz, R. ; Glinzer, A. ; Huber, K. ; Haas, H. ; Kaissis, G. ; Feuchtinger, A. ; Aichler, M. ; Sporns, P.B. ; Höltke, C. ; Stölting, M. ; Schilling, F. ; Botnar, R.M. ; Kimm, M.A. ; Faber, C. ; Walch, A.K. ; Zernecke, A. ; Karst, U. ; Wildgruber, M.
Mass Spectrometry imaging of atherosclerosis-affine Gadofluorine following Magnetic Resonance imaging.Schüttrumpf, L. ; Marschner, S. ; Scheu, K. ; Hess J. ; Rietzler, S. ; Walch, A.K. ; Baumeister, P. ; Kirchner, T. ; Ganswindt, U. ; Zitzelsberger, H. ; Belka, C. ; Maihoefer, C.
Definitive chemoradiotherapy in patients with squamous cell cancers of the head and neck-results from an unselected cohort of the clinical cooperation group "Personalized Radiotherapy in Head and Neck Cancer".Renner, S. ; Blutke, A. ; Clauss, S. ; Deeg, C.A. ; Kemter, E. ; Merkus, D. ; Wanke, R. ; Wolf, E.
Porcine models for studying complications and organ crosstalk in diabetes mellitus.Hofmann, I. ; Kemter, E. ; Theobalt, N. ; Fiedler, S. ; Bidlingmaier, M. ; Hinrichs, A. ; Aichler, M. ; Burkhardt, K. ; Klymiuk, N. ; Wolf, E. ; Wanke, R. ; Blutke, A.
Linkage between growth retardation and pituitary cell morphology in a dystrophin-deficient pig model of Duchenne muscular dystrophy.Kunzke, T. ; Buck, A. ; Prade, V.M. ; Feuchtinger, A. ; Prokopchuk, O. ; Martignoni, M.E. ; Heisz, S. ; Hauner, H. ; Janssen, K.P. ; Walch, A.K. ; Aichler, M.
Derangements of amino acids in cachectic skeletal muscle are caused by mitochondrial dysfunction.Altamura, S. ; Vegi, N.M. ; Hoppe, P.S. ; Schroeder, T. ; Aichler, M. ; Walch, A.K. ; Okreglicka, K. ; Hültner, L. ; Schneider, M. ; Ladinig, C. ; Kuklik-Roos, C. ; Mysliwietz, J. ; Janik, D. ; Neff, F. ; Rathkolb, B. ; Hrabě de Angelis, M. ; Buske, C. ; da Silva, A.R. ; Muedder, K. ; Conrad, M. ; Ganz, T. ; Kopf, M. ; Muckenthaler, M.U. ; Bornkamm, G.W.
Glutathione peroxidase 4 and vitamin E control reticulocyte maturation, stress erythropoiesis and iron homeostasis.Kreutzer, L. ; Aichler, M. ; Walch, A.K.
In situ metabolomics in cancer tissue by high-resolution mass spectrometry imaging.Baumann, P. ; Schriever, S.C. ; Kullmann, S. ; Zimprich, A. ; Feuchtinger, A. ; Amarie, O.V. ; Peter, A. ; Walch, A.K. ; Gailus-Durner, V. ; Fuchs, H. ; Hrabě de Angelis, M. ; Wurst, W. ; Tschöp, M.H. ; Heni, M. ; Hölter, S.M. ; Pfluger, P.T.
Dusp8 affects hippocampal size and behavior in mice and humans.Correa-Gallegos, D. ; Jiang, D. ; Christ, S. ; Ramesh, P. ; Ye, H. ; Wannemacher, J. ; Kalgudde Gopal, S. ; Yu, Q. ; Aichler, M. ; Walch, A.K. ; Mirastschijski, U. ; Volz, T. ; Rinkevich, Y.
Patch repair of deep wounds by mobilized fascia.Yang, L. ; Gradl, R. ; Dierolf, M. ; Möller, W. ; Kutschke, D. ; Feuchtinger, A. ; Hehn, L. ; Donnelley, M. ; Günther, B. ; Achterhold, K. ; Walch, A.K. ; Stöger, T. ; Razansky, D. ; Pfeiffer, F. ; Morgan, K.S. ; Schmid, O.
Multimodal precision imaging of pulmonary nanoparticle delivery in mice: Dynamics of application, spatial distribution, and dosimetry.Seitz, S. ; Kwon, Y. ; Hartleben, G. ; Jülg, J. ; Sekar, R. ; Krahmer, N. ; Najafi, B. ; Loft, A. ; Gancheva, S. ; Stemmer, K. ; Feuchtinger, A. ; Hrabě de Angelis, M. ; Müller, T.D. ; Mann, M. ; Blüher, M. ; Roden, M. ; Berriel Diaz, M. ; Behrends, C. ; Gilleron, J. ; Herzig, S. ; Zeigerer, A.
Hepatic Rab24 controls blood glucose homeostasis via improving mitochondrial plasticity.Stutte, S. ; Ruf, J. ; Kugler, I. ; Ishikawa-Ankerhold, H. ; Blutke, A. ; Marconi, P. ; Maeda, T. ; Kaisho, T. ; Krug, A. ; Lauterbach, H. ; Colonna, M. ; von Andrian, U. ; Brocker, T.
Type-I interferon regulates ghrelin-levels leading to anorexia and weight loss while promoting inflammatory immune responses.Arndt, D. ; Fux, R. ; Blutke, A. ; Schwaiger, J. ; El-Matbouli, M. ; Sutter, G. ; Langenmayer, M.C.
Proliferative kidney disease and proliferative darkening syndrome are linked with brown trout (Salmo trutta fario) mortalities in the pre-alpine Isar River.Sammer, M. ; Teiluf, K. ; Girst, S. ; Greubel, C. ; Reindl, J. ; Ilicic, K. ; Walsh, D.W.M. ; Aichler, M. ; Walch, A.K. ; Combs, S.E. ; Wilkens, J.J. ; Dollinger, G. ; Schmid, T.E.
Beam size limit for pencil minibeam radiotherapy determined from side effects in an in-vivo mouse ear model.Wagner, A. ; Hofmeister, O. ; Rolland, S.G. ; Maiser, A. ; Aasumets, K. ; Schmitt, S. ; Schorpp, K.K. ; Feuchtinger, A. ; Hadian, K. ; Schneider, S. ; Zischka, H. ; Leonhardt, H. ; Conradt, B. ; Gerhold, J.M. ; Wolf, A.
Mitochondrial Alkbh1 localizes to mtRNA granules and its knockdown induces the mitochondrial UPR in humans and C. elegans.Murakami, M. ; Rhayem, Y. ; Kunzke, T. ; Sun, N. ; Feuchtinger, A. ; Ludwig, P. ; Strom, T.M. ; Gomez-Sanchez, C. ; Knösel, T. ; Kirchner, T. ; Williams, T.A. ; Reincke, M. ; Walch, A.K. ; Beuschlein, F.
In situ metabolomics of aldosterone-producing adenomas.Sun, N. ; Kunzke, T. ; Sbiera, S. ; Kircher, S. ; Feuchtinger, A. ; Aichler, M. ; Herterich, S. ; Ronchi, C.L. ; Weigand, I. ; Schlegel, N. ; Waldmann, J. ; Fragoso, M.C.V. ; Whitsett, T.G. ; Gill, A.J. ; Fassnacht, M. ; Walch, A.K. ; Kroiss, M.
Prognostic relevance of steroid sulfation in adrenocortical carcinoma revealed by molecular phenotyping using high resolution mass spectrometry imaging.Siebert, C. ; Ciato, D. ; Murakami, M. ; Frei-Stuber, L. ; Perez-Rivas, L.G. ; Monteserin-Garcia, J.L. ; Noelting, S. ; Maurer, J. ; Feuchtinger, A. ; Walch, A.K. ; Haak, H.R. ; Bertherat, J. ; Mannelli, M. ; Fassnacht, M. ; Korpershoek, E. ; Reincke, M. ; Stalla, G.K. ; Hantel, C. ; Beuschlein, F.
Heat shock protein 90 as a prognostic marker and therapeutic target for adrenocortical carcinoma.Renner, S. ; Martins, A.S. ; Streckel, E. ; Braun-Reichhart, C. ; Backman, M. ; Prehn, C. ; Klymiuk, N. ; Bähr, A. ; Blutke, A. ; Landbrecht-Schessl, C. ; Wünsch, A. ; Kessler, B. ; Kurome, M. ; Hinrichs, A. ; Koopmans, S.J. ; Krebs, S. ; Kemter, E. ; Rathkolb, B. ; Nagashima, H. ; Blum, H. ; Ritzmann, M. ; Wanke, R. ; Aigner, B. ; Adamski, J. ; Hrabě de Angelis, M. ; Wolf, E.
Mild maternal hyperglycemia in INSC93S transgenic pigs causes impaired glucose tolerance and metabolic alterations in neonatal offspring.Rehm, S.R.T. ; Smirnova, N.F. ; Morrone, C. ; Götzfried, J. ; Feuchtinger, A. ; Pedersen, J. ; Korkmaz, B. ; Yildirim, A.Ö. ; Jenne, D.
Premedication with a cathepsin C inhibitor alleviates early primary graft dysfunction in mouse recipients after lung transplantation.Yang, L. ; Gradl, R. ; Feuchtinger, A. ; Morgan, K.S. ; Kutschke, D. ; Stöger, T. ; Razansky, D. ; Walch, A.K. ; Pfeiffer, F. ; Schmidt, O.
Novel imaging tolls for deciphering pulmonary aerosol deposition with single-cell resolution in non-dissected murine lungs.Sigmund, F. ; Pettinger, S. ; Kube, M. ; Schneider, F. ; Schifferer, M. ; Schneider, S. ; Efremova, M.V. ; Pujol-Martí, J. ; Aichler, M. ; Walch, A.K. ; Misgeld, T. ; Dietz, H. ; Westmeyer, G.G.
Iron-sequestering nanocompartments as multiplexed Electron Microscopy gene reporters.Schneider, A. ; Kurz, S. ; Manske, K. ; Janas, M.K. ; Heikenwälder, M. ; Misgeld, T. ; Aichler, M. ; Weissmann, S.F. ; Zischka, H. ; Knolle, P. ; Wohlleber, D.
Single organelle analysis to characterize mitochondrial function and crosstalk during viral infection.Wintergerst, L. ; Selmansberger, M. ; Maihoefer, C. ; Schuettrumpf, L. ; Walch, A.K. ; Wilke, C. ; Pitea, A. ; Woischke, C. ; Baumeister, P. ; Kirchner, T. ; Belka, C. ; Ganswindt, U. ; Zitzelsberger, H. ; Unger, K. ; Hess J.
A 16q24.3 4-gene mRNA signature predicts outcome in radio(chemo)therapy-treated head and neck squamous cell carcinoma.Hess J. ; Unger, K. ; Maihoefer, C. ; Schuettrumpf, L. ; Schneider, L. ; Heider, T. ; Weber, P. ; Marschner, S. ; Braselmann, H. ; Kuger, S. ; Pflugradt, U. ; Baumeister, P. ; Walch, A.K. ; Woischke, C. ; Kirchner, T. ; Werner, M. ; Werner, K. ; Baumann, M. ; Budach, V. ; Combs, S.E. ; Debus, J. ; Grosu, A.-L. ; Krause, M. ; Roedel, C. ; Stuschke, M. ; Zips, D. ; Zitzelsberger, H. ; Ganswindt, U. ; Henke, M. ; Belka, C.
A five-microRNA-signature predicts recurrence and survival in HPV-negative HNSCC.Wiesner, M. ; Glawischnig, W. ; Lutzmann, I. ; Grimm, F. ; Blutke, A.
Autochthonous Taenia crassiceps infection in a ring-tailed lemur (Lemur catta) in the Salzburg Zoo.Huber, K. ; Kunzke, T. ; Buck, A. ; Langer, R. ; Luber, B. ; Feuchtinger, A. ; Walch, A.K.
Multimodal analysis of formalin-fixed and paraffin-embedded tissue by MALDI imaging and fluorescence in situ hybridization for combined genetic and metabolic analysis.Backman, M. ; Flenkenthaler, F. ; Blutke, A. ; Dahlhoff, M. ; Ländström, E. ; Renner, S. ; Philippou-Massier, J. ; Krebs, S. ; Rathkolb, B. ; Prehn, C. ; Grzybek, M. ; Coskun, Ü. ; Rothe, M. ; Adamski, J. ; Hrabě de Angelis, M. ; Wanke, R. ; Fröhlich, T. ; Arnold, G.J. ; Blum, H. ; Wolf, E.
Multi-omics insights into functional alterations of the liver in insulin-deficient diabetes mellitus.von Gamm, M. ; Schaub, A. ; Jones, A. ; Wolf, C. ; Behrens, G. ; Lichti, J. ; Essig, K. ; Macht, A. ; Pircher, J. ; Ehrlich, A. ; Davari, K. ; Chauhan, D. ; Busch, B. ; Wurst, W. ; Feederle, R. ; Feuchtinger, A. ; Tschöp, M.H. ; Friedel, C.C. ; Hauck, S.M. ; Sattler, M. ; Geerlof, A. ; Hornung, V. ; Heissmeyer, V. ; Schulz, C. ; Heikenwalder, M. ; Glasmacher, E.
Immune homeostasis and regulation of the interferon pathway require myeloid-derived Regnase-3.Dombrowsky, A. ; Schauer, J. ; Sammer, M. ; Blutke, A. ; Walsh, D.W.M. ; Schwarz, B. ; Bartzsch, S. ; Feuchtinger, A. ; Reindl, J. ; Combs, S.E. ; Dollinger, G. ; Schmid, T.E.
Acute skin damage and late radiation-induced fibrosis and inflammation in murine ears after high-dose irradiation.Segal, J. ; Mülleder, M. ; Krüger, A. ; Adler, T. ; Scholze-Wittler, M. ; Becker, L. ; Calzada-Wack, J. ; Garrett, L. ; Hölter, S.M. ; Rathkolb, B. ; Rozman, J. ; Rácz, I. ; Fischer, R. ; Busch, D.H. ; Neff, F. ; Klingenspor, M. ; Klopstock, T. ; Grüning, N.M. ; Michel, S. ; Lukaszewska-McGreal, B. ; Voigt, I. ; Hartmann, L. ; Timmermann, B. ; Lehrach, H. ; Wolf, E. ; Wurst, W. ; Gailus-Durner, V. ; Fuchs, H. ; Hrabě de Angelis, M. ; Schrewe, H. ; Yuneva, M. ; Ralser, M.
Low catalytic activity is insufficient to induce disease pathology in triosephosphate isomerase deficiency.Bechmann, N. ; Poser, I. ; Seifert, V. ; Greunke, C. ; Ullrich, M. ; Qin, N. ; Walch, A.K. ; Peitzsch, M. ; Robledo, M. ; Pacak, K. ; Pietzsch, J. ; Richter, S. ; Eisenhofer, G.
Impact of extrinsic and intrinsic hypoxia on catecholamine biosynthesis in absence or presence of Hif2 alpha in pheochromocytoma cells.Sperling, S. ; Fiedler, P. ; Lechner, M. ; Pollithy, A. ; Ehrenberg, S. ; Schiefer, A.I. ; Kenner, L. ; Feuchtinger, A. ; Kühn, R. ; Swinerd, G. ; Schmidt-Supprian, M. ; Strobl, L.J. ; Zimber-Strobl, U.
Chronic CD30 signaling in B cells results in lymphomagenesis by driving the expansion of plasmablasts and B1 cells.Ratner, C. ; He, Z. ; Grunddal, K.V. ; Skov, L.J. ; Hartmann, B. ; Zhang, F. ; Feuchtinger, A. ; Bjerregaard, A. ; Christoffersen, C. ; Tschöp, M.H. ; Finan, B. ; DiMarchi, R.D. ; Leinninger, G.M. ; Williams, K.W. ; Clemmensen, C. ; Holst, B.
Long-acting neurotensin synergizes with liraglutide to reverse obesity through a melanocortin-dependent pathway.Gujrati, V. ; Prakash, J. ; Malekzadeh Najafabadi, J. ; Stiel, A.-C. ; Klemm, U. ; Mettenleiter, G. ; Aichler, M. ; Walch, A.K. ; Ntziachristos, V.
Bioengineered bacterial vesicles as biological nano-heaters for optoacoustic imaging.Papathomas, T.G. ; Sun, N. ; Chortis, V. ; Taylor, A.E. ; Arlt, W. ; Richter, S. ; Eisenhofer, G. ; Ruiz-Babot, G. ; Guasti, L. ; Walch, A.K.
Novel methods in adrenal research: A metabolomics approach.Ogrinc Wagner, A. ; Friedrich, V. ; Barthels, C. ; Marconi, P. ; Blutke, A. ; Brombacher, F. ; Brocker, T.
Strain specific maturation of Dendritic cells and production of IL-1β controls CD40-driven colitis.Norheim, F. ; Hasin-Brumshtein, Y. ; Vergnes, L. ; Chella Krishnan, K. ; Pan, C. ; Seldin, M.M. ; Hui, S.T. ; Mehrabian, M. ; Zhou, Z. ; Gupta, S. ; Parks, B.W. ; Walch, A.K. ; Reue, K. ; Hofmann, S.M. ; Arnold, A.P. ; Lusis, A.J.
Gene-by-sex interactions in mitochondrial functions and cardio-metabolic traits.Balluff, B. ; Buck, A. ; Martin-Lorenzo, M. ; Dewez, F. ; Langer, R. ; McDonnell, L.A. ; Walch, A.K. ; Heeren, R.M.A.
Integrative clustering in mass spectrometry imaging for enhanced patient stratification.Yang, L. ; Feuchtinger, A. ; Möller, W. ; Ding, Y. ; Kutschke, D. ; Möller, G. ; Schittny, J.C. ; Burgstaller, G. ; Hofmann, W. ; Stöger, T. ; Razansky, D. ; Walch, A.K. ; Schmid, O.
Three-dimensional quantitative co-mapping of pulmonary morphology and nanoparticle distribution with cellular resolution in non-dissected murine lungs.Görgülü, K. ; Diakopoulos, K.N. ; Ai, J. ; Schoeps, B. ; Kabacaoglu, D. ; Karpathaki, A.F. ; Ciecielski, K.J. ; Kaya-Aksoy, E. ; Ruess, D.A. ; Berninger, A. ; Kowalski, M. ; Stevanovic, M. ; Wörmann, S.M. ; Wartmann, T. ; Zhao, Y. ; Halangk, W. ; Voronina, S. ; Tepikin, A. ; Schlitter, A.M. ; Steiger, K. ; Artati, A. ; Adamski, J. ; Aichler, M. ; Walch, A.K. ; Jastroch, M. ; Hartleben, G. ; Mantzoros, C.S. ; Weichert, W. ; Schmid, R.M. ; Herzig, S. ; Krüger, A. ; Sainz, B. ; Lesina, M. ; Algül, H.
Levels of the autophagy-related 5 protein affect progression and metastasis of pancreatic tumors in mice.Harrison, L. ; Schriever, S.C. ; Feuchtinger, A. ; Kyriakou, E. ; Baumann, P. ; Pfuhlmann, K. ; Messias, A.C. ; Walch, A.K. ; Tschöp, M.H. ; Pfluger, P.T.
Fluorescent blood-brain barrier tracing shows intact leptin transport in obese mice.Hess J. ; Unger, K. ; Maihoefer, C. ; Schüttrumpf, L. ; Wintergerst, L. ; Heider, T. ; Weber, P. ; Marschner, S. ; Braselmann, H. ; Samaga, D. ; Kuger, S. ; Pflugradt, U. ; Baumeister, P. ; Walch, A.K. ; Woischke, C. ; Kirchner, T. ; Werner, M. ; Werner, K. ; Baumann, M. ; Budach, V. ; Combs, S.E. ; Debus, J. ; Grosu, A.-L. ; Krause, M. ; Linge, A. ; Rödel, C. ; Stuschke, M. ; Zips, D. ; Zitzelsberger, H. ; Ganswindt, U. ; Henke, M. ; Belka, C.
A five-microRNA signature predicts survival and disease control of patients with head and neck cancer negative for HPV-infection.Fernandez, I.E. ; Sun, N. ; Wei, M. ; Witting, M. ; Aichler, M. ; Verleden, S. ; Schmitt-Kopplin, P. ; Walch, A.K. ; Eickelberg, O.
Pharmacometabolic effect of pirfenidone treatment in IPF detected by high resolution MALDI-FTICR imaging.Clemmensen, C. ; Jall, S. ; Kleinert, M. ; Quarta, C. ; Gruber, T. ; Reber, J. ; Sachs, S. ; Fischer, K. ; Feuchtinger, A. ; Karlas, A. ; Simonds, S.E. ; Grandl, G. ; Loher, D. ; Sanchez-Quant, E. ; Keipert, S. ; Jastroch, M. ; Hofmann, S.M. ; Nascimento, E.B.M. ; Schrauwen, P. ; Ntziachristos, V. ; Cowley, M.A. ; Finan, B. ; Müller, T.D. ; Tschöp, M.H.
Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes (vol 9, 4304, 2018).Fernandez, I.E. ; Sun, N. ; Wei, M. ; Witting, M. ; Aichler, M. ; Verleden, S. ; Schmitt-Kopplin, P. ; Eickelberg, O. ; Walch, A.K.
Pharmacometabolic response to pirfenidone treatment in pulmonary fibrosis detected by high resolution MALDI FTICR-mass spectrometry imaging.Clemmensen, C. ; Jall, S. ; Kleinert, M. ; Quarta, C. ; Gruber, T. ; Reber, J. ; Sachs, S. ; Fischer, K. ; Feuchtinger, A. ; Karlas, A. ; Simonds, S.E. ; Grandl, G. ; Loher, D. ; Sanchez-Quant, E. ; Keipert, S. ; Jastroch, M. ; Hofmann, S.M. ; Nascimento, E.B.M. ; Schrauwen, P. ; Ntziachristos, V. ; Cowley, M.A. ; Finan, B. ; Müller, T.D. ; Tschöp, M.H.
Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes.Wintergerst, L. ; Selmansberger, M. ; Maihoefer, C. ; Schüttrumpf, L. ; Walch, A.K. ; Wilke, C. ; Pitea, A. ; Woischke, C. ; Baumeister, P. ; Kirchner, T. ; Belka, C. ; Ganswindt, U. ; Zitzelsberger, H. ; Unger, K. ; Hess J.
A prognostic mRNA expression signature of four 16q24.3 genes in radio(chemo)therapy-treated head and neck squamous cell carcinoma (HNSCC).Suwandhi, L. ; Hausmann, S. ; Braun, A. ; Gruber, T. ; Heinzmann, S.S. ; Gálvez, E.J.C. ; Buck, A. ; Legutko, B. ; Israel, A. ; Feuchtinger, A. ; Haythorne, E. ; Staiger, H. ; Heni, M. ; Häring, H.-U. ; Schmitt-Kopplin, P. ; Walch, A.K. ; Cáceres, C.G. ; Tschöp, M.H. ; Rutter, G.A. ; Strowig, T. ; Elsner, M. ; Ussar, S.
Chronic d-serine supplementation impairs insulin secretion.Zoni, E. ; Buck, A. ; Feuchtinger, A. ; Spahn, M. ; Walch, A.K. ; Kruithof-de Julio, M.
Metabolic signature in lethal vs. nonlethal prostate cancer.Clemen, C.S. ; Winter, L. ; Strucksberg, K.H. ; Berwanger, C. ; Türk, M. ; Kornblum, C. ; Florin, A. ; Aguilar-Pimentel, J.A. ; Amarie, O.V. ; Becker, L. ; Garrett, L. ; Hans, W. ; Moreth, K. ; Neff, F. ; Pingen, L. ; Rathkolb, B. ; Rácz, I. ; Rozman, J. ; Treise, I. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Vorgerd, M. ; Eichinger, L. ; Schröder, R.
The heterozygous R155C VCP mutation: Toxic in humans! Harmless in mice?Jain, M. ; Mann, T.D. ; Stulić, M. ; Rao, S.P. ; Kirsch, A. ; Pullirsch, D. ; Strobl, X. ; Rath, C. ; Reissig, L. ; Moreth, K. ; Klein-Rodewald, T. ; Bekeredjian, R. ; Gailus-Durner, V. ; Fuchs, H. ; Hrabě de Angelis, M. ; Pablik, E. ; Cimatti, L. ; Martin, D. ; Zinnanti, J. ; Graier, W.F. ; Sibilia, M. ; Frank, S. ; Levanon, E.Y. ; Jantsch, M.F.
RNA editing of Filamin A pre-mRNA regulates vascular contraction and diastolic blood pressure.International Wheat Genome Sequencing Consortium (Eversole, K. ; Feuillet, C. ; Keller, B. ; Rogers, J. ; Stein, N. ; Appels, R.) ; Pozniak, C.J. ; Choulet, F. ; Distelfeld, A. ; Poland, J. ; Ronen, G ; Sharpe, A.G. ; Pozniak, C. ; Barad, O. ; Baruch, K. ; Choulet, F. ; Keeble-Gagnère, G. ; Mascher, M. ; Ben-Zvi, G. ; Josselin, A.A. ; Himmelbach, A. ; Balfourier, F. ; Gutierrez-Gonzalez, J. ; Hayden, M. ; Josselin, A.A. ; Koh, C. ; Muehlbauer, G. ; Pasam, R.K. ; Paux, E. ; Rigault, P. ; Tibbits, J. ; Tiwari, V. ; Choulet, F. ; Spannagl, M. ; Lang, D. ; Gundlach, H. ; Haberer, G. ; Mayer, K.F.X. ; Ormanbekova, D. ; Paux, E. ; Prade, V.M. ; Šimková, H. ; Wicker, T. ; Swarbreck, D. ; Rimbert, H. ; Guilhot, N. ; Kaithakottil, G. ; Keilwagen, J. ; Leroy, P. ; Lux, T. ; Twardziok, S.O. ; Venturini, L. ; Juhász, A ; Abrouk, M ; Fischer, I.P. ; Uauy, C. ; Borrill, P ; Ramirez-Gonzalez, R.H. ; Arnaud, D. ; Chalabi, S. ; Chalhoub, B. ; Cory, A. ; Datla, R. ; Davey, M.W. ; Hayden, M. ; Jacobs, J. ; Robinson, S.J. ; Steuernagel, B. ; Tibbits, J. ; Tiwari, V. ; van Ex, F. ; Wulff, B.B.H. ; Robinson, S.J. ; Cory, A. ; Benhamed, M. ; Paux, E. ; Bendahmane, A. ; Concia, L. ; Latrasse, D. ; Rogers, J. ; Alaux, M. ; Bartoš, J. ; Bellec, A. ; Berges, H. ; Doležel, J. ; Frenkel, Z ; Gill, B. ; Korol, A. ; Letellier, T. ; Olsen, O.A. ; Singh, K. ; Valárik, M. ; van der Vossen, E. ; Vautrin, S. ; Weining, S. ; Korol, A. ; Frenkel, Z. ; Fahima, T. ; Glikson, V. ; Raats, D. ; Tiwari, V. ; Gill, B. ; Paux, E. ; Číhalíková, J. ; Toegelová, H. ; Vrána, J. ; Sourdille, P. ; Darrier, B. ; Barabaschi, D. ; Cattivelli, L ; Hernandez, P. ; Galvez, S. ; Budak, H. ; Jones, J.D.G. ; Witek, K. ; Yu, G. ; Small, I. ; Melonek, J. ; Zhou, R. ; Juhász, A. ; Belova, T. ; Kanyuka, K. ; King, R. ; Nilsen, K. ; Walkowiak, S. ; Cuthbert, R. ; Datla, R. ; Knox, R. ; Wiebe, K. ; Xiang, D. ; Rohde, A. ; Golds, T. ; Čížková, J. ; Akpinar, B.A. ; Biyiklioglu, S. ; Muehlbauer, G. ; Gao, L. ; Gutierrez-Gonzalez, J. ; N'Daiye, A. ; Číhalíková, J. ; Kubaláková, M. ; Šafář, J. ; Berges, H. ; Bellec, A. ; Vautrin, S. ; Alaux, M. ; Alfama, F. ; Adam-Blondon, A.F. ; Flores, R. ; Guerche, C. ; Letellier, T. ; Loaec, M. ; Quesneville, H. ; Condie, J. ; Ens, J. ; Koh, C. ; Maclachlan, R. ; Tan, Y. ; Paux, E. ; Alberti, A. ; Aury, J.M. ; Barbe, V. ; Couloux, A. ; Cruaud, C. ; Labadie, K. ; Mangenot, S. ; Wincker, P. ; Gill, B. ; Kaur, G. ; Luo, M. ; Sehgal, S. ; Chhuneja, P. ; Gupta, O.P. ; Jindal, S. ; Kaur, P. ; Malik, P. ; Sharma, P. ; Yadav, B. ; Singh, N.K. ; Khurana, J. ; Chaudhary, C. ; Khurana, P. ; Kumar, V. ; Mahato, A. ; Mathur, S. ; Sevanthi, A. ; Sharma, N. ; Tomar, R.S. ; Jacobs, J. ; Alaux, M. ; Bellec, A. ; Berges, H. ; Frenkel, Z. ; Gill, B. ; Korol, A. ; van der Vossen, E. ; Vautrin, S. ; Kaur, G. ; Luo, M. ; Sehgal, S. ; Bartoš, J. ; Holušová, K. ; Plíhal, O. ; Clark, M.D. ; Heavens, D. ; Kettleborough, G. ; Wright, J. ; Valárik, M. ; Abrouk, M. ; Balcárková, B. ; Holušová, K. ; Hu, Y. ; Luo, M. ; Salina, E. ; Ravin, N. ; Skryabin, K. ; Beletsky, A. ; Kadnikov, V. ; Mardanov, A. ; Nesterov, M. ; Rakitin, A. ; Sergeeva, E. ; Handa, H. ; Kanamori, H. ; Katagiri, S. ; Kobayashi, F. ; Nasuda, S. ; Tanaka, T. ; Wu, J. ; Hayden, M. ; Rigault, P. ; Cattonaro, F. ; Jiumeng, M. ; Kugler, K.G. ; Pfeifer, M. ; Sandve, S. ; Xun, X. ; Zhan, B. ; Abrouk, M. ; Batley, J. ; Bayer, P.E. ; Edwards, D. ; Hayashi, S. ; Tulpová, Z. ; Visendi, P. ; Weining, S. ; Cui, L. ; Du, X. ; Feng, K. ; Nie, X. ; Tong, W.G. ; Wang, L. ; Galvez, S. ; Lux, T. ; Ramirez-Gonzalez, R.H. ; Venturini, L. ; Hernandez, P ; Kanyuka, K ; Paux, E.
Shifting the limits in wheat research and breeding using a fully annotated reference genome.Sun, N. ; Fernandez, I.E. ; Wei, M. ; Witting, M. ; Aichler, M. ; Feuchtinger, A. ; Burgstaller, G. ; Verleden, S.E. ; Schmitt-Kopplin, P. ; Eickelberg, O. ; Walch, A.K.
Pharmacometabolic response to pirfenidone in pulmonary fibrosis detected by MALDI-FTICR-MSI.Gora, T. ; Burkhardt, R. ; Umkehrer, S. ; Herzen, J. ; Schilling, D. ; Feuchtinger, A. ; Walch, A.K. ; Schmid, T.E. ; Multhoff, G. ; Noel, P.B. ; Rummeny, E.J. ; Pfeiffer, F. ; Combs, S.E. ; Wilkens, J.J.
Detection of radiation induced lung fibrosis using x-ray dark-field imaging in a murine model.Martin-Medina, A. ; Lehmann, M. ; Burgy, O. ; Hermann, S. ; Baarsma, H.A. ; Wagner, D.E. ; De Santis, M. ; Ciolek, F. ; Hofer, T.P. ; Frankenberger, M. ; Aichler, M. ; Lindner, M. ; Gesierich, W. ; Guenther, A. ; Walch, A.K. ; Coughlan, C. ; Wolters, P. ; Lee, J.S. ; Behr, J. ; Königshoff, M.
Increased extracellular vesicles mediate WNT5A signaling in idiopathic pulmonary fibrosis.Buck, A. ; Heijs, B. ; Beine, B. ; Schepers, J. ; Cassese, A. ; Heeren, R.M.A. ; McDonnell, L.A. ; Henkel, C. ; Walch, A.K. ; Balluff, B.
Round robin study of formalin-fixed paraffin-embedded tissues in mass spectrometry imaging.Maihoefer, C. ; Schüttrumpf, L. ; Macht, C. ; Pflugradt, U. ; Hess J. ; Schneider, L. ; Woischke, C. ; Walch, A.K. ; Baumeister, P. ; Kirchner, T. ; Zitzelsberger, H. ; Belka, C. ; Ganswindt, U.
Postoperative (chemo) radiation in patients with squamous cell cancers of the head and neck - clinical results from the cohort of the clinical cooperation group "Personalized Radiotherapy in Head and Neck Cancer".Bräuer, K. ; Brockers, K. ; Moneer, J. ; Feuchtinger, A. ; Wollscheid-Lengeling, E. ; Lengeling, A. ; Wolf, A.
Phylogenetic and genomic analyses of the ribosomal oxygenases Riox1 (No66) and Riox2 (Mina53) provide new insights into their evolution.Saller, M.M. ; Huettl, R.E. ; Mayer, J.M. ; Feuchtinger, A. ; Krug, C. ; Holzbach, T. ; Volkmer, E.
Validation of a novel animal model for sciatic nerve repair with an adipose-derived stem cell loaded fibrin conduit.Lohöfer, F. ; Hoffmann, L. ; Buchholz, R. ; Huber, K. ; Glinzer, A. ; Kosanke, K. ; Feuchtinger, A. ; Aichler, M. ; Feuerecker, B. ; Kaissis, G. ; Rummeny, E.J. ; Höltke, C. ; Faber, C. ; Schilling, F. ; Botnar, R.M. ; Walch, A.K. ; Karst, U. ; Wildgruber, M.
Molecular imaging of myocardial infarction with Gadofluorine P – A combined magnetic resonance and mass spectrometry imaging approach.Rodriguez Camargo, D.C. ; Garg, D. ; Buday, K. ; Frankó, A. ; Rodriguez Camargo, A. ; Schmidt, F. ; Cox, S.J. ; Suladze, S. ; Haslbeck, M. ; Mideksa, Y.G. ; Gemmecker, G. ; Aichler, M. ; Mettenleiter, G. ; Schulz, M. ; Walch, A.K. ; Hrabě de Angelis, M. ; Feige, M.J. ; Sierra, C.A. ; Conrad, M. ; Tripsianes, K. ; Ramamoorthy, A. ; Reif, B.
hIAPP forms toxic oligomers in plasma.Wilke, C. ; Braselmann, H. ; Hess J. ; Klymenko, S.V. ; Chumak, V.V. ; Zakhartseva, L.M. ; Bakhanova, E.V. ; Walch, A.K. ; Selmansberger, M. ; Samaga, D. ; Weber, P. ; Schneider, L. ; Fend, F. ; Bösmüller, H.C. ; Zitzelsberger, H. ; Unger, K.
A genomic copy number signature predicts radiation exposure in post-Chernobyl breast cancer.André, V. ; Gau, C. ; Scheideler, A. ; Aguilar-Pimentel, J.A. ; Amarie, O.V. ; Becker, L. ; Garrett, L. ; Hans, W. ; Hölter, S.M. ; Janik, D. ; Moreth, K. ; Neff, F. ; Östereicher, M.A. ; Rácz, I. ; Rathkolb, B. ; Rozman, J. ; Bekeredjian, R. ; Graw, J. ; Klingenspor, M. ; Klopstock, T. ; Ollert, M. ; Schmidt-Weber, C.B. ; Wolf, E. ; Wurst, W. ; Gailus-Durner, V. ; Brielmeier, M. ; Fuchs, H. ; Hrabě de Angelis, M.
Laboratory mouse housing conditions can be improved using common environmental enrichment without compromising data.Treise, I. ; Huber, E.M. ; Klein-Rodewald, T. ; Heinemeyer, W. ; Grassmann, S.A. ; Basler, M. ; Adler, T. ; Rathkolb, B. ; Helming, L. ; Andres, C. ; Klaften, M. ; Landbrecht, C. ; Wieland, T. ; Strom, T.M. ; McCoy, K.D. ; Macpherson, A.J. ; Wolf, E. ; Groettrup, M. ; Ollert, M. ; Neff, F. ; Gailus-Durner, V. ; Fuchs, H. ; Hrabě de Angelis, M. ; Groll, M. ; Busch, D.H.
Defective immuno- and thymoproteasome assembly causes severe immunodeficiency.Xie, K. ; Ryan, D.P. ; Pearson, B.L. ; Henzel, K.S. ; Neff, F. ; Vidal, R.O. ; Hennion, M. ; Lehmann, I. ; Schleif, M. ; Schröder, S. ; Adler, T. ; Rathkolb, B. ; Rozman, J. ; Schütz, A.L. ; Prehn, C. ; Mickael, M.E. ; Weiergräber, M. ; Adamski, J. ; Busch, D.H. ; Ehninger, G. ; Matynia, A. ; Jackson, W.S. ; Wolf, E. ; Fuchs, H. ; Gailus-Durner, V. ; Bonn, S. ; Hrabě de Angelis, M. ; Ehninger, D.
Epigenetic alterations in longevity regulators, reduced life span, and exacerbated aging-related pathology in old father offspring mice.Frankó, A. ; Rodriguez Camargo, D.C. ; Böddrich, A. ; Garg, D. ; Rodriguez Camargo, A. ; Rathkolb, B. ; Janik, D. ; Aichler, M. ; Feuchtinger, A. ; Neff, F. ; Fuchs, H. ; Wanker, E.E. ; Reif, B. ; Häring, H.-U. ; Peter, A. ; Hrabě de Angelis, M.
Epigallocatechin gallate (EGCG) reduces the intensity of pancreatic amyloid fibrils in human islet amyloid polypeptide (hIAPP) transgenic mice.Sun, N. ; Wu, Y. ; Nanba, K. ; Sbiera, S. ; Kircher, S. ; Kunzke, T. ; Aichler, M. ; Berezowska, S. ; Reibetanz, J. ; Rainey, W.E. ; Fassnacht, M. ; Walch, A.K. ; Kroiss, M.
High resolution tissue mass spectrometry imaging reveals a refined functional anatomy of the human adult adrenal gland.Dalke, C. ; Neff, F. ; Bains, S.K. ; Bright, S. ; Lord, D.J. ; Reitmeir, P. ; Rößler, U. ; Samaga, D. ; Unger, K. ; Braselmann, H. ; Wagner, F. ; Greiter, M. ; Gomolka, M. ; Hornhardt, S. ; Kunze, S. ; Kempf, S.J. ; Garrett, L. ; Hölter, S.M. ; Wurst, W. ; Rosemann, M. ; Azimzadeh, O. ; Tapio, S. ; Aubele, M. ; Theis, F.J. ; Hoeschen, C. ; Slijepcevic, P. ; Kadhim, M. ; Atkinson, M.J. ; Zitzelsberger, H. ; Kulka, U. ; Graw, J.
Lifetime study in mice after acute low-dose ionizing radiation: A multifactorial study with special focus on cataract risk.Absmaier, M. ; Napieralski, R. ; Schuster, T. ; Aubele, M. ; Walch, A.K. ; Magdolen, V. ; Dorn, J. ; Gross, E. ; Harbeck, N. ; Noske, A. ; Kiechle, M. ; Schmitt, M.
PITX2 DNA-methylation predicts response to anthracycline-based adjuvant chemotherapy in triple-negative breast cancer patients.Ingold, I. ; Berndt, C. ; Schmitt, S. ; Doll, S. ; Poschmann, G. ; Buday, K. ; Roveri, A. ; Peng, X. ; Porto Freitas, F. ; Seibt, T. ; Mehr, L. ; Aichler, M. ; Walch, A.K. ; Lamp, D. ; Jastroch, M. ; Miyamoto, S. ; Wurst, W. ; Ursini, F. ; Arnér, E.S.J. ; Fradejas-Villar, N. ; Schweizer, U. ; Zischka, H. ; Friedmann Angeli, J.P.F. ; Conrad, M.
Selenium utilization by GPX4 is required to prevent hydroperoxide-induced ferroptosis.Molatore, S. ; Kügler, A. ; Irmler, M. ; Wiedemann, T. ; Neff, F. ; Feuchtinger, A. ; Beckers, J. ; Robledo, M. ; Roncaroli, F. ; Pellegata, N.S.
Characterization of neuroendocrine tumors in heterozygous mutant MENX rats: A novel model of invasive medullary thyroid carcinoma.Aichler, M. ; Kunzke, T. ; Buck, A. ; Sun, N. ; Ackermann, M. ; Jonigk, D. ; Gaumann, A. ; Walch, A.K.
Molecular similarities and differences from human pulmonary fibrosis and corresponding mouse model: MALDI imaging mass spectrometry in comparative medicine.Wilke, C. ; Hess J. ; Klymenko, S.V. ; Chumak, V.V. ; Zakhartseva, L.M. ; Bakhanova, E.V. ; Feuchtinger, A. ; Walch, A.K. ; Selmansberger, M. ; Braselmann, H. ; Schneider, L. ; Pitea, A. ; Steinhilber, J. ; Fend, F. ; Bösmüller, H.C. ; Zitzelsberger, H. ; Unger, K.
Expression of miRNA-26b-5p and its target TRPS1 is associated with radiation exposure in post-Chernobyl breast cancer.Prade, V.M. ; Gundlach, H. ; Twardziok, S.O. ; Chapman, B. ; Tan, C.S. ; Langridge, P. ; Schulman, A.H. ; Stein, N. ; Waugh, R. ; Zhang, G. ; Platzer, M. ; Li, C. ; Spannagl, M. ; Mayer, K.F.X.
The pseudogenes of barley.Ingold, I. ; Berndt, C. ; Schmitt, S. ; Doll, S. ; Poschmann, G. ; Roveri, A. ; Peng, X. ; Freitas, F.P. ; Aichler, M. ; Jastroch, M. ; Ursini, F. ; Arner, E.S.J. ; Fradejas-Villar, N. ; Schweizer, U. ; Zischka, H. ; Friedmann Angeli, J.P.F. ; Conrad, M.
Selenium utilization by GPX4 was an evolutionary requirement to prevent hydroperoxide-induced ferroptosis.Klaeger, S. ; Heinzlmeir, S. ; Wilhelm, M. ; Polzer, H. ; Vick, B. ; Koenig, P.A. ; Reinecke, M. ; Ruprecht, B. ; Petzoldt, S. ; Meng, C. ; Zecha, J. ; Reiter, K. ; Qiao, H. ; Helm, D. ; Koch, H. ; Schoof, M. ; Canevari, G. ; Casale, E. ; Depaolini, S.R. ; Feuchtinger, A. ; Wu, Z. ; Schmidt, T. ; Rueckert, L. ; Becker, W. ; Huenges, J. ; Garz, A.K. ; Gohlke, B.O. ; Zolg, D.P. ; Kayser, G. ; Vooder, T. ; Preissner, R. ; Hahne, H. ; Tõnisson, N. ; Kramer, K. ; Götze, K. ; Bassermann, F. ; Schlegl, J. ; Ehrlich, H.C. ; Aiche, S. ; Walch, A.K. ; Greif, P.A. ; Schneider, S. ; Felder, E.R. ; Ruland, J. ; Médard, G. ; Jeremias, I. ; Spiekermann, K. ; Kuster, B.
The target landscape of clinical kinase drugs.Rodriguez Camargo, D.C. ; Korshavn, K.J. ; Jussupow, A. ; Raltchev, K. ; Goricanec, D. ; Fleisch, M. ; Sarkar, R. ; Xue, K. ; Aichler, M. ; Mettenleiter, G. ; Walch, A.K. ; Camilloni, C. ; Hagn, F. ; Reif, B. ; Ramamoorthy, A.
Stabilization and structural analysis of a membrane-associated hIAPP aggregation intermediate.Desbenoit, N. ; Walch, A.K. ; Spengler, B. ; Brunelle, A. ; Römpp, A.
Correlative mass spectrometry imaging, applying TOF-SIMS and AP-MALDI to a single tissue section.Jacobs, L. ; Habringer, S. ; Slawska, J. ; Huber, K. ; Hauf, E. ; Li, Z. ; Refaeli, Y. ; Schwaiger, M. ; Rudelius, M. ; Walch, A.K. ; Keller, U.
Functional imaging in combination with mutation status aids prediction of response to inhibiting B-cell receptor signaling in lymphoma.Urban, C. ; Buck, A. ; Siveke, J.T. ; Lordick, F. ; Luber, B. ; Walch, A.K. ; Aichler, M.
PAXgene fixation enables comprehensive metabolomic and proteomic analyses of tissue specimens by MALDI MSI.Fichter, C.D. ; Przypadlo, C.M. ; Buck, A. ; Herbener, N. ; Riedel, B. ; Schäfer, L. ; Nakagawa, H. ; Walch, A.K. ; Reinheckel, T. ; Werner, M. ; Lassmann, S.
A new model system identifies EGFR/HER2 and HER2/HER3 heterodimers as potent inducers of oesophageal epithelial cell invasion.Kumar, S. ; Rathkolb, B. ; Sabrautzki, S. ; Krebs, S. ; Kemter, E. ; Becker, L. ; Beckers, J. ; Bekeredjian, R. ; Brommage, R. ; Calzada-Wack, J. ; Garrett, L. ; Hölter, S.M. ; Horsch, M. ; Klingenspor, M. ; Klopstock, T. ; Moreth, K. ; Neff, F. ; Rozman, J. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Wolf, E. ; Aigner, B.
Standardized, systemic phenotypic analysis reveals kidney dysfunction as main alteration of Kctd1I27N mutant mice.Koch, M. ; de Jong, J.S. ; Glatz, J. ; Symvoulidis, P. ; Lamberts, L.E. ; Adams, A.L.L. ; Kranendonk, M.E.G. ; van Scheltinga, A.T. ; Aichler, M. ; Jansen, L. ; de Vries, J. ; Lub-de Hooge, M. ; Schröder, C.P. ; Jorritsma-Smit, A. ; Linssen, M.D. ; de Boer, E. ; van der Vegt, B. ; Nagengast, W.B. ; Elias, S.G. ; Oliveira, S. ; Witkamp, A.J. ; Mali, W.P.Th.M. ; van der Wall, E. ; Garcia-Allende, P. ; van Diest, P.J. ; de Vries, E.G. ; Walch, A.K. ; van Dam, G.M. ; Ntziachristos, V.
Fluorescently labeled bevacizumab in human breast cancer: Defining the classification threshold.Schlecht, A. ; Leimbeck, S.V. ; Jägle, H. ; Feuchtinger, A. ; Tamm, E.R. ; Braunger, B.M.
Deletion of endothelial TGF-β signaling leads to choroidal neovascularization.Yang, F. ; Aubele, M. ; Walch, A.K. ; Gross, E. ; Napieralski, R. ; Zhao, S. ; Ahmed, N. ; Kiechle, M. ; Reuning, U. ; Dorn, J. ; Sweep, F.C. ; Magdolen, V. ; Schmitt, M.
Tissue kallikrein-related peptidase 4 (KLK4), a novel biomarker in triple-negative breast cancer.Kunzke, T. ; Balluff, B. ; Feuchtinger, A. ; Buck, A. ; Langer, R. ; Luber, B. ; Lordick, F. ; Zitzelsberger, H. ; Aichler, M. ; Walch, A.K.
Native glycan fragments detected by MALDI-FT-ICR mass spectrometry imaging impact gastric cancer biology and patient outcome.Altamura, S. ; Vegi, N. ; Hueltner, L. ; Schneider, M. ; Höppe, P. ; Schroeder, T. ; Canli, Ö. ; Greten, F.R. ; Aichler, M. ; Walch, A.K. ; Neff, F. ; Janik, D. ; Kuklik-Roos, C. ; Ladinig, C. ; Mysliwietz, J. ; Rathkolb, B. ; Buske, C. ; Conrad, M. ; Muckenthaler, M.U. ; Bornkamm, G.W.
Lack of the ferroptosis inhibitor GPX4 in erythroid cells causes a block in reticulocyte maturation and a hypoxic signature with impaired hepcidin regulation.Düwel, S. ; Hundshammer, C. ; Gersch, M. ; Feuerecker, B. ; Steiger, K. ; Buck, A. ; Walch, A.K. ; Haase, A. ; Glaser, S.J. ; Schwaiger, M. ; Schilling, F.
Imaging of pH in vivo using hyperpolarized 13C-labelled zymonic acid.Hachmöller, O. ; Aichler, M. ; Schwamborn, K. ; Lutz, L. ; Werner, M. ; Sperling, M. ; Walch, A.K. ; Karst, U.
Investigating the influence of standard staining procedures on the copper distribution and concentration in Wilson's disease liver samples by laser ablation-inductively coupled plasma-mass spectrometry.Medina, A.M. ; Vierkotten, S. ; Lehmann, M. ; Wagner, D. ; Baarsma, H. ; Höfer, T. ; Frankerberger, M. ; Behr, J. ; Aichler, M. ; Walch, A. ; Königshoff, M.
Wnt5a is secreted by extracellular vesicles in pulmonary fibrosis and increases fibroblasts proliferation.Aichler, M. ; Borgmann, D.M. ; Krumsiek, J. ; Buck, A. ; MacDonald, P.E. ; Fox, J.E.M. ; Lyon, J. ; Light, P.E. ; Keipert, S. ; Jastroch, M. ; Feuchtinger, A. ; Müller, N.S. ; Sun, N. ; Palmer, A. ; Alexandrov, T. ; Hrabě de Angelis, M. ; Neschen, S. ; Tschöp, M.H. ; Walch, A.K.
N-acyl taurines and acylcarnitines cause an imbalance in insulin synthesis and secretion provoking β cell dysfunction in type 2 diabetes.Kaklamanos, A. ; Rozman, J. ; Roulis, M. ; Karagianni, N. ; Armaka, M. ; Wu, M. ; Brachthäuser, L. ; Calzada-Wack, J. ; Horsch, M. ; Beckers, J. ; Rathkolb, B. ; Adler, T. ; Neff, F. ; Wolf, E. ; Gailus-Durner, V. ; Fuchs, H. ; Hrabě de Angelis, M. ; Kollias, G.
Extensive phenotypic characterization of a new transgenic mouse reveals pleiotropic perturbations in physiology due to mesenchymal hGH minigene expression.Ryan, D.P. ; Henzel, K.S. ; Pearson, B.L. ; Siwek, M.E. ; Papazoglou, A. ; Guo, L. ; Paesler, K. ; Yu, M. ; Müller, R. ; Xie, K. ; Schröder, S. ; Becker, L. ; Garrett, L. ; Hölter, S.M. ; Neff, F. ; Rácz, I. ; Rathkolb, B. ; Rozman, J. ; Ehninger, G. ; Klingenspor, M. ; Klopstock, T. ; Wolf, E. ; Wurst, W. ; Zimmer, A.D. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Sidiropoulou, K. ; Weiergräber, M. ; Zhou, Y. ; Ehninger, D.
A paternal methyl donor-rich diet altered cognitive and neural functions in offspring mice.Smida, J. ; Xu, H. ; Zhang, Y. ; Baumhoer, D. ; Ribi, S. ; Kovac, M. ; von Luettichau, I. ; Bielack, S. ; O'Leary, V.B. ; Leib-Mösch, C. ; Frishman, D. ; Nathrath, M.
Genome-wide analysis of somatic copy number alterations and chromosomal breakages in osteosarcoma.Arlt, W. ; Lang, K. ; Sitch, A.J. ; Dietz, A.S. ; Rhayem, Y. ; Bancos, I. ; Feuchtinger, A. ; Chortis, V. ; Gilligan, L.C. ; Ludwig, P. ; Riester, A. ; Asbach, E. ; Hughes, B.A. ; O'Neil, D.M. ; Bidlingmaier, M. ; Tomlinson, J.W. ; Hassan-Smith, Z.K. ; Rees, D.A. ; Adolf, C. ; Hahner, S. ; Quinkler, M. ; Dekkers, T. ; Deinum, J. ; Biehl, M. ; Keevil, B.G. ; Shackleton, C.H.L. ; Deeks, J.J. ; Walch, A.K. ; Beuschlein, F. ; Reincke, M.
Steroid metabolome analysis reveals prevalent glucocorticoid excess in primary aldosteronism.Jall, S. ; Sachs, S. ; Clemmensen, C. ; Finan, B. ; Neff, F. ; DiMarchi, R.D. ; Tschöp, M.H. ; Müller, T.D. ; Hofmann, S.M.
Monomeric GLP-1/GIP/glucagon triagonism corrects obesity, hepatosteatosis, and dyslipidemia in female mice.von Heyking, K. ; Calzada-Wack, J. ; Göllner, S. ; Neff, F. ; Schmidt, O. ; Hensel, T. ; Schirmer, D. ; Fasan, A. ; Esposito, I. ; Müller-Tidow, C. ; Sorensen, P.H.B. ; Burdach, S. ; Richter, G.H.
The endochondral bone protein CHM1 sustains an undifferentiated, invasive phenotype, promoting lung metastasis in Ewing sarcoma.Dislich, B. ; Stein, A. ; Seiler, C.A. ; Kröll, D. ; Berezowska, S. ; Zlobec, I. ; Galvan, J.A. ; Slotta-Huspenina, J. ; Walch, A.K. ; Langer, R.
Expression patterns of programmed death-ligand 1 in esophageal adenocarcinomas: Comparison between primary tumors and metastases.Knüppel, L. ; Ishikawa, Y. ; Aichler, M. ; Heinzelmann, K. ; Hatz, R. ; Behr, J. ; Walch, A.K. ; Bächinger, H.P. ; Eickelberg, O. ; Staab-Weijnitz, C.A.
A novel antifibrotic mechanism of nintedanib and pirfenidone: Inhibition of collagen fibril assembly.Echtler, K. ; Konrad, I. ; Lorenz, M. ; Schneider, S. ; Hofmaier, S. ; Plenagl, F. ; Stark, K. ; Czermak, T. ; Tirniceriu, A. ; Eichhorn, M.E. ; Walch, A.K. ; Enders, G. ; Massberg, S. ; Schulz, C.
Platelet GPIIb supports initial pulmonary retention but inhibits subsequent proliferation of melanoma cells during hematogenic metastasis.Rodriguez Camargo, D.C. ; Tripsianes, K. ; Buday, K. ; Frankó, A. ; Göbl, C. ; Hartlmüller, C. ; Sarkar, R. ; Aichler, M. ; Mettenleiter, G. ; Schulz, M. ; Böddrich, A. ; Erck, C. ; Martens, H. ; Walch, A.K. ; Madl, T. ; Wanker, E.E. ; Conrad, M. ; Hrabě de Angelis, M. ; Reif, B.
The redox environment triggers conformational changes and aggregation of hIAPP in Type II Diabetes.Frankó, A. ; Neschen, S. ; Rozman, J. ; Rathkolb, B. ; Aichler, M. ; Feuchtinger, A. ; Brachthäuser, L. ; Neff, F. ; Kovarova, M. ; Wolf, E. ; Fuchs, H. ; Häring, H.-U. ; Peter, A. ; Hrabě de Angelis, M.
Bezafibrate ameliorates diabetes via reduced steatosis and improved hepatic insulin sensitivity in diabetic TallyHo mice.Buck, A. ; Aichler, M. ; Huber, K. ; Walch, A.K.
In situ metabolomics in cancer by mass spectrometry imaging.Szibor, M. ; Dhandapani, P.K. ; Dufour, E. ; Holmström, K.M. ; Zhuang, Y. ; Salwig, I. ; Wittig, I. ; Heidler, J. ; Gizatullina, Z. ; Gainutdinov, T. ; German Mouse Clinic Consortium (Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Aguilar-Pimentel, J.A. ; Schmidt-Weber, C.B. ; Becker, L. ; Adler, T. ; Treise, I. ; Horsch, M. ; Beckers, J. ; Moreth, K. ; Garrett, L. ; Hölter, S.M. ; Zimprich, A. ; Wurst, W. ; Hans, W. ; Amarie, O.V. ; Graw, J. ; Rozman, J. ; Calzada-Wack, J. ; Da Silva-Buttkus, P. ; Neff, F. ; Rácz, I. ; Rathkolb, B. ; Östereicher, M.A. ; Steinkamp, R. ; Lengger, C. ; Maier, H. ; Stoeger, C. ; Leuchtenberger, S.) ; Nandania, J. ; Velagapudi,V. ; Wietelmann, A. ; Rustin, P. ; Gellerich, F.N. ; Jacobs, H.T. ; Braun, T.
Broad AOX expression in a genetically tractable mouse model does not disturb normal physiology.Ma, X. ; van Phi, V. ; Kimm, M.A. ; Prakash, J. ; Kessler, H. ; Kosanke, K. ; Feuchtinger, A. ; Aichler, M. ; Gupta, A. ; Rummeny, E.J. ; Eisenblätter, M. ; Siveke, J. ; Walch, A.K. ; Braren, R. ; Ntziachristos, V. ; Wildgruber, M.
Integrin-targeted hybrid fluorescence molecular tomography/X-ray computed tomography for imaging tumor progression and early response in non-small cell lung cancer.Zhao, S. ; Dorn, J. ; Napieralski, R. ; Walch, A.K. ; Diersch, S. ; Kotzsch, M. ; Ahmed, N. ; Hooper, J. ; Kiechle, M. ; Schmitt, M. ; Magdolen, V.
Plasmin(Ogen) serves as a favorable biomarker for prediction of survival in advanced high-grade serous ovarian cancer.Koch, M. ; de Jong, J.S. ; Glatz, J. ; Symvoulidis, P. ; Lamberts, L.E. ; Adams, A.L.L. ; Kranendonk, M.E.G. ; Terwisscha van Scheltinga, A.G. ; Aichler, M. ; Jansen, L. ; de Vries, J. ; Lub-de, Hoog, M.N. ; Schröder, C.P. ; Jorritsma-Smit, A. ; Linssen, M.D. ; de Boer, E. ; van der Vegt, B. ; Nagengast, W.B. ; Elisas,S.G. ; Oliveira, S. ; Witkamp, A.J. ; Mali, W.P.Th.M. ; van der Wall, E. ; Gracia-Allende, P.B. ; van Diest, P.J. ; de Vries, E.G. ; Walch, A.K. ; van Dam, G.M. ; Ntziachristos, V.
Threshold analysis and biodistribution of fluorescently labeled bevacizumab in human breast cancer.Doll, S. ; Proneth, B. ; Tyurina, A.A. ; Panzilius, E. ; Kobayashi, S. ; Ingold, I. ; Irmler, M. ; Beckers, J. ; Aichler, M. ; Walch, A.K. ; Prokisch, H. ; Trümbach, D. ; Mao, G. ; Qu, F. ; Bayir, H. ; Füllekrug, J. ; Scheel, C. ; Wurst, W. ; Schick, J. ; Kagan, V.E. ; Friedmann Angeli, J.P.F. ; Conrad, M.
ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition.Luber, B. ; Keller, S. ; Zwingenberger, G. ; Ebert, K. ; Maier, D. ; Geier, B. ; Theis, F.J. ; Hasenauer, J. ; Huge, S. ; Meyer-Hermann, M. ; Dehghany, J. ; Walch, A.K. ; Aichler, M. ; Lordick, F. ; Haffner, I.
Identification of predictive response and resistance factors to targeted therapy in gastric cancer using a systems medicine approach.Hensel, T. ; Giorgi, C. ; Becker-Dettling, F. ; Calzada-Wack, J. ; Neff, F. ; Schmidt, O. ; Schäfer, B. ; Burdach, S. ; Richter, G.
Combined targeting of the EWS/ETS Ttanscriptional program by BET bromodomain and PI3K pathway inhibition blocks tumorigenicity and increases apoptosis in ewing sarcoma.von Heyking, K. ; Roth, L.C. ; Ertl, M. ; Schmidt, O. ; Calzada-Wack, J. ; Neff, F. ; Lawlor, E.R. ; Burdach, S. ; Richter, G.
The posterior HOXD locus: Its contribution to phenotype and malignancy of Ewing sarcoma.Hensel, T. ; Giorgi, C. ; Becker-Dettling, F. ; Calzada-Wack, J. ; Neff, F. ; Schmidt, O. ; Schäfer, B.W. ; Burdach, S. ; Richter, G.H.
Inhibition of BET bromodomain proteins and the PI3K pathway in Ewing sarcoma down regulates the specific transcriptional program, inhibits tumorigenicity and increases apoptosis in Ewing sarcoma.Eisenberg, T. ; Abdellatif, M. ; Schroeder, S. ; Primessnig, U. ; Stekovic, S. ; Pendl, T. ; Harger, A. ; Schipke, J. ; Zimmermann, A. ; Schmidt, A. ; Tong, M. ; Ruckenstuhl, C. ; Dammbrueck, C. ; Gross, A.S. ; Herbst, V. ; Magnes, C. ; Trausinger, G. ; Narath, S. ; Meinitzer, A. ; Hu, Z. ; Kirsch, A. ; Eller, K. ; Carmona-Gutierrez, D. ; Büttner, S. ; Pietrocola, F. ; Knittelfelder, O. ; Schrepfer, E. ; Rockenfeller, P. ; Simonini, C. ; Rahn, A. ; Horsch, M. ; Moreth, K. ; Beckers, J. ; Fuchs, H. ; Gailus-Durner, V. ; Neff, F. ; Janik, D. ; Rathkolb, B. ; Rozman, J. ; Hrabě de Angelis, M. ; Moustafa, T. ; Haemmerle, G. ; Mayr, M. ; Willeit, P. ; von Frieling-Salewsky, M. ; Pieske, B. ; Scorrano, L. ; Pieber, T.R. ; Pechlaner, R. ; Willeit, J. ; Sigrist, S.J. ; Linke, W.A. ; Mühlfeld, C. ; Sadoshima, J. ; Dengjel, J. ; Kiechl, S. ; Kroemer, G. ; Sedej, S. ; Madeo, F.
Cardioprotection and lifespan extension by the natural polyamine spermidine.Fuchs, H. ; Sabrautzki, S. ; Przemeck, G.K.H. ; Leuchtenberger, S. ; Lorenz-Depiereux, B. ; Becker, L. ; Rathkolb, B. ; Horsch, M. ; Garrett, L. ; Östereicher, M.A. ; Hans, W. ; Abe, K. ; Sagawa, N. ; Rozman, J. ; Vargas Panesso, I.L. ; Sandholzer, M. ; Lisse, T.S. ; Adler, T. ; Aguilar-Pimentel, J.A. ; Calzada-Wack, J. ; Ehrhard, N. ; Elvert, R. ; Gau, C. ; Hölter, S.M. ; Micklich, K. ; Moreth, K. ; Prehn, C. ; Puk, O. ; Rácz, I. ; Stoeger, C. ; Vernaleken, A. ; Michel, D. ; Diener, S. ; Wieland, T. ; Adamski, J. ; Bekeredjian, R. ; Lengger, C. ; Maier, H. ; Neff, F. ; Ollert, M. ; Stöger, T. ; Yildirim, A.Ö. ; Strom, T.M. ; Zimmer, A. ; Wolf, E. ; Wurst, W. ; Klopstock, T. ; Beckers, J. ; Gailus-Durner, V. ; Hrabě de Angelis, M.
The first Scube3 mutant mouse line with pleiotropic phenotypic alterations.Abdelmoula, W.M. ; Balluff, B. ; Englert, S. ; Dijkstra, J. ; Reinders, M.J.T. ; Walch, A.K. ; McDonnell, L.A. ; Lelieveldt, B.P.F.
Data-driven identification of prognostic tumor subpopulations using spatially mapped t-SNE of mass spectrometry imaging data.Schenck, T.L. ; Lin, S. ; Stewart, J.K. ; Koban, K.C. ; Aichler, M. ; Rezaeian, F. ; Giunta, R.E.
Sensory reanimation of the hand by transfer of the superficial branch of the radial nerve to the median and ulnar nerve.Gross, E. ; van Tinteren, H. ; Li, Z. ; Raab, S. ; Meul, C. ; Avril, S. ; Laddach, N. ; Aubele, M. ; Propping, C. ; Gkazepis, A. ; Schmitt, M. ; Meindl, A. ; Nederlof, P.M. ; Kiechle, M. ; Lips, E.H.
Identification of BRCA1-like triple-negative breast cancers by quantitative multiplex-ligation-dependent probe amplification (MLPA) analysis of BRCA1-associated chromosomal regions: A validation study.Wiedemann, T. ; Hofbaur, S. ; Loell, E. ; Rieder, G.
A C-Terminal coiled-coil region of CagL is responsible for Helicobacter Pylori-induced Il-8 expression.Wittmann, A. ; Grimm, M. ; Scherthan, H. ; Horsch, M. ; Beckers, J. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Ford, S.J. ; Burton, N.C. ; Razansky, D. ; Trümbach, D. ; Aichler, M. ; Walch, A.K. ; Calzada-Wack, J. ; Neff, F. ; Wurst, W. ; Hartmann, T. ; Floß, T.
Sphingomyelin synthase 1 is essential for male fertility in mice.Kempf, S.J. ; Janik, D. ; Barjaktarovic, Z. ; Braga-Tanaka III, I. ; Tanaka, S. ; Neff, F. ; Saran, A. ; Larsen, M.R. ; Tapio, S.
Chronic low-dose-rate ionising radiation affects the hippocampal phosphoproteome in the ApoE-/- Alzheimer's mouse model.Feuchtinger, A. ; Walch, A.K. ; Dobosz, M.
Deep tissue imaging: A review from a preclinical cancer research perspective.Finan, B. ; Clemmensen, C. ; Zhu, Z. ; Stemmer, K. ; Gauthier, K. ; Müller, L. ; de Angelis, M. ; Moreth, K. ; Neff, F. ; Perez-Tilve, D. ; Fischer, K. ; Lutter, D. ; Sánchez-Garrido, M.A. ; Liu, P. ; Tuckermann, J.P. ; Malehmir, M. ; Healy, M.E. ; Weber, A. ; Heikenwälder, M. ; Jastroch, M. ; Kleinert, M. ; Jall, S. ; Brandt, S. ; Flamant, F. ; Schramm, K.-W. ; Biebermann, H. ; Döring, Y. ; Weber, C. ; Habegger, K.M. ; Keuper, M. ; Gelfanov, V. ; Liu, F. ; Köhrle, J. ; Rozman, J. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Hofmann, S.M. ; Yang, B. ; Tschöp, M.H. ; DiMarchi, R. ; Müller, T.D.
Chemical hybridization of glucagon and thyroid hormone optimizes therapeutic Impact for metabolic disease.Kong, B. ; Bruns, P. ; Behler, N.A. ; Chang, L. ; Schlitter, A.M. ; Cao, J. ; Gewies, A. ; Ruland, J. ; Fritzsche, S. ; Valkovskaya, N. ; Jian, Z. ; Regel, I. ; Raulefs, S. ; Irmler, M. ; Beckers, J. ; Friess, H. ; Erkan, M. ; Müller, N.S. ; Roth, S. ; Hackert, T. ; Esposito, I. ; Theis, F.J. ; Kleeff, J. ; Michalski, C.W.
Dynamic landscape of pancreatic carcinogenesis reveals early molecular networks of malignancy.Huber, M. ; Mall, R. ; Braselmann, H. ; Feuchtinger, A. ; Molatore, S. ; Lindner, K. ; Walch, A.K. ; Gross, E. ; Schmitt, M. ; Falkenberg, N. ; Aubele, M.
uPAR enhances malignant potential of triple-negative breast cancer by directly interacting with uPA and IGF1R.Stark, K. ; Philippi, V. ; Stockhausen, S. ; Busse, J. ; Antonelli, A. ; Miller, M. ; Schubert, I. ; Hoseinpour, P. ; Chandraratne, S. ; von Brühl, M.L. ; Gärtner, F. ; Lorenz, M. ; Agresti, A. ; Coletti, R. ; Antoine, D.J. ; Heermann, R. ; Jung, K. ; Reese, S. ; Laitinen, I. ; Schwaiger, M. ; Walch, A.K. ; Sperandio, M. ; Nawroth, P.P. ; Reinhardt, C. ; Jäckel, S. ; Bianchi, M.E. ; Massberg, S.
Disulfide HMGB1 derived from platelets coordinates venous thrombosis in mice.Chekkoury, A. ; Nunes, A. ; Gateau, J. ; Symvoulidis, P. ; Feuchtinger, A. ; Bézière, N. ; Ovsepian, S.V. ; Walch, A.K. ; Ntziachristos, V.
High-resolution multispectral optoacoustic tomography of the vascularization and constitutive hypoxemia of cancerous tumors.Regn, M. ; Laggerbauer, B. ; Jentzsch, C. ; Ramanujam, D. ; Ahles, A. ; Sichler, S. ; Calzada-Wack, J. ; Koenen, R. ; Braun, A. ; Nieswandt, B. ; Engelhardt, S.
Peptidase inhibitor 16 is a membrane-tethered regulator of chemerin processing in the myocardium.Ly, A. ; Buck, A. ; Balluff, B. ; Sun, N. ; Gorzolka, K. ; Feuchtinger, A. ; Janssen, K.P. ; Kuppen, P.J. ; van de Velde, C.J. ; Weirich, G. ; Erlmeier, F. ; Langer, R. ; Aubele, M. ; Zitzelsberger, H. ; McDonnell, L.A. ; Aichler, M. ; Walch, A.K.
High-mass-resolution MALDI mass spectrometry imaging of metabolites from formalin-fixed paraffin-embedded tissue.Mendler, C.T. ; Feuchtinger, A. ; Heid, I. ; Aichler, M. ; D'Alessandria, C. ; Pirsig, S. ; Blechert, B. ; Wester, H.J. ; Braren, R. ; Walch, A.K. ; Skerra, A. ; Schwaiger, M.
Tumor uptake of anti-CD20 Fabs depends on tumor perfusion.Bader, E. ; Migliorini, A. ; Gegg, M. ; Moruzzi, N. ; Gerdes, J.M. ; Roscioni, S. ; Bakhti, M. ; Brandl, E. ; Irmler, M. ; Beckers, J. ; Aichler, M. ; Feuchtinger, A. ; Leitzinger, C. ; Zischka, H. ; Wang-Sattler, R. ; Jastroch, M. ; Tschöp, M.H. ; Machicao, F. ; Staiger, H. ; Häring, H.-U. ; Chmelova, H. ; Chouinard, J.A. ; Oskolkov, N. ; Korsgren, O. ; Speier, S. ; Lickert, H.
Identification of proliferative and mature β-cells in the islets of Langerhans.von Heyking, K. ; Roth, L.C. ; Ertl, M. ; Schmidt, O. ; Calzada-Wack, J. ; Neff, F. ; Lawlor, E.R. ; Burdach, S. ; Richter, G.H.
The posterior HOXD locus: Its contribution to phenotype and malignancy of Ewing sarcoma.Mall, S. ; Yusufi, N. ; Wagner, R. ; Klar, R. ; Bianchi, H. ; Steiger, K. ; Straub, M. ; Audehm, S. ; Laitinen, I. ; Aichler, M. ; Peschel, C. ; Ziegler, S. ; Mustafa, M. ; Schwaiger, M. ; D'Alessandria, C. ; Krackhardt, A.M.
Immuno-PET imaging of engineered human T cells in tumors.Lichtmannegger, J. ; Leitzinger, C. ; Wimmer, R. ; Schmitt, S. ; Schulz, S. ; Kabiri, Y. ; Eberhagen, C. ; Rieder, T. ; Janik, D. ; Neff, F. ; Straub, B.K. ; Schirmacher, P. ; DiSpirito, A.A. ; Bandow, N. ; Baral, B.S. ; Flatley, A. ; Kremmer, E. ; Denk, G.U. ; Reiter, F.P. ; Hohenester, S. ; Eckardt-Schupp, F. ; Dencher, N.A. ; Adamski, J. ; Sauer, V. ; Niemietz, C. ; Schmidt, H.H. ; Merle, U. ; Gotthardt, D.N. ; Kroemer, G. ; Weiss, K.H. ; Zischka, H.
Methanobactin reverses acute liver failure in a rat model of Wilson disease.Huber, M. ; Falkenberg, N. ; Hauck, S.M. ; Priller, M. ; Braselmann, H. ; Feuchtinger, A. ; Walch, A.K. ; Schmitt, M. ; Aubele, M.
Cyr61 and YB-1 are novel interacting partners of uPAR and elevate the malignancy of triple-negative breast cancer.Frankó, A. ; Huypens, P. ; Neschen, S. ; Irmler, M. ; Rozman, J. ; Rathkolb, B. ; Neff, F. ; Prehn, C. ; Dubois, G. ; Baumann, M. ; Massinger, R. ; Gradinger, D. ; Przemeck, G.K.H. ; Repp, B. ; Aichler, M. ; Feuchtinger, A. ; Schommers, P. ; Stöhr, O. ; Sanchez-Lasheras, C. ; Adamski, J. ; Peter, A. ; Prokisch, H. ; Beckers, J. ; Walch, A.K. ; Fuchs, H. ; Wolf, E. ; Schubert, M. ; Wiesner, R.J. ; Hrabě de Angelis, M.
Bezafibrate improves insulin sensitivity and metabolic flexibility in STZ-treated diabetic mice.Boeckh-Behrens, T. ; Kleine, J.F. ; Zimmer, C. ; Neff, F. ; Scheipl, F. ; Pelisek, J. ; Schirmer, L. ; Nguyen, K.H. ; Karatas, D. ; Poppert, H.
Thrombus histology suggests cardioembolic cause in cryptogenic stroke.Eden, M. ; Meder, B. ; Völkers, M. ; Poomvanicha, M. ; Domes, K. ; Branchereau, M. ; Marck, P. ; Will, R. ; Bernt, A. ; Rangrez, A. ; Busch, M. ; German Mouse Clinic Consortium (Adler, T. ; Aguilar-Pimentel, J.A. ; Becker, L. ; Beckers, J. ; Busch, D.H. ; Calzada-Wack, J. ; Fuchs, H. ; Gailus-Durner, V. ; Garrett, L. ; Graw, J. ; Götz, A. ; Hans, W. ; Hölter, S.M. ; Horsch, M. ; Klein-Rodewald, T. ; Lengger, C. ; Leuchtenberger, S. ; Maier, H. ; Neff, F. ; Ollert, M. ; Prehn, C. ; Puk, O. ; Rácz, I. ; Rathkolb, B. ; Rozman, J. ; Schrewe, A. ; Schulz, H. ; Stoeger, C. ; Tost, M. ; Wurst, W.) ; Hrabě de Angelis, M. ; Heymes, C. ; Rottbauer, W. ; Most, P. ; Hofmann, F. ; Frey, N.
Erratum: Myoscape controls cardiac calcium cycling and contractility via regulation of L-type calcium channel surface expression.Cassese, A. ; Ellis, S. ; Ogrinc Potočnik, N. ; Burgermeister, E. ; Ebert, M. ; Walch, A.K. ; van den Maagdenberg, A.M. ; McDonnell, L.A. ; Heeren, R.M. ; Balluff, B.
Spatial autocorrelation in mass spectrometry imaging.Côme, C. ; Cvrljevic, A. ; Khan, M.M. ; Treise, I. ; Adler, T. ; Aguilar-Pimentel, J.A. ; Au-Yeung, B. ; Sittig, E. ; Laajala, T.D. ; Chen, Y. ; Oeder, S. ; Calzada-Wack, J. ; Horsch, M. ; Aittokallio, T. ; Busch, D.H. ; Ollert, M. ; Neff, F. ; Beckers, J. ; Gailus-Durner, V. ; Fuchs, H. ; Hrabě de Angelis, M. ; Chen, Z. ; Lahesmaa, R. ; Westermarck, J.
CIP2A promotes T-cell activation and immune response to Listeria monocytogenes infection.Eden, M. ; Meder, B. ; Völkers, M. ; Poomvanicha, M. ; Domes, K. ; Branchereau, M. ; Marck, P. ; Will, R. ; Bernt, A. ; Rangrez, A. ; Busch, M. ; German Mouse Clinic Consortium (Adler, T. ; Aguilar-Pimentel, J.A. ; Becker, L. ; Beckers, J. ; Busch, D.H. ; Calzada-Wack, J. ; Fuchs, H. ; Gailus-Durner, V. ; Garrett, L. ; Graw, J. ; Götz, A. ; Hans, W. ; Hölter, S.M. ; Horsch, M. ; Klein-Rodewald, T. ; Lengger, C. ; Leuchtenberger, S. ; Maier, H. ; Neff, F. ; Ollert, M. ; Prehn, C. ; Puk, O. ; Rácz, I. ; Rathkolb, B. ; Rozman, J. ; Schrewe, A. ; Schulz, H. ; Stoeger, C. ; Tost, M. ; Wurst, W. ; Frey, N.) ; Hrabě de Angelis, M. ; Heymes, C. ; Rottbauer, W. ; Most, P. ; Hofmann, F.
Myoscape controls cardiac calcium cycling and contractility via regulation of L-type calcium channel surface expression.Buck, A. ; Balluff, B. ; Voss, A. ; Langer, R. ; Zitzelsberger, H. ; Aichler, M. ; Walch, A.K.
How suitable is MALDI-TOF for metabolite imaging from clinical formalin-fixed and paraffin-embedded tissue samples in comparison to MALDI-FT-ICR mass spectrometry?Dorn, J. ; Yassouridis, A. ; Walch, A.K. ; Diamandis, E.P. ; Schmitt, M. ; Kiechle, M. ; Wang, P. ; Drecoll, E. ; Schmalfeldt, B. ; Loessner, D. ; Kotzsch, M. ; Magdolen, V.
Assessment of kallikrein-related peptidase 5 (KLK5) protein expression in tumor tissue of advanced ovarian cancer patients by immunohistochemistry and ELISA: Correlation with clinical outcome.Hachmöller, O. ; Aichler, M. ; Schwamborn, K. ; Lutz, L. ; Werner, M. ; Sperling, M. ; Walch, A.K. ; Karst, U.
Element bioimaging of liver needle biopsy specimens from patients with Wilson's disease by laser ablation-inductively coupled plasma-mass spectrometry.Trajkovic-Arsic, M. ; Kalideris, E. ; Sun, N. ; Feuchtinger, A. ; Gupta, A. ; Aichler, M. ; Schmid, R.M. ; Walch, A.K. ; Siveke, J.T.
Identification of metabolic changes in pancreatic ductal adenocarcinoma.Haffner, I. ; Luber, B. ; Maier, D. ; Geier, B. ; Theis, F.J. ; Meyer-Hermann, M. ; Walch, A.K. ; Kretzschmar, A.K. ; von Weikersthal, L.F. ; Knorrenschild, J.R. ; Schierle, K. ; Wittekind, C. ; Lordick, F.
Clinical validation of response and resistance factor candidates to targeted therapy in Gastric Cancer (GC).Gross, E. ; Brunet, T. ; Napieralski, R. ; Singer, T. ; Aubele, M. ; Schmitt, M. ; Meindl, A. ; Lips, E. ; Kiechle, M.
Validation of a BRCAness test to select for targeted therapies in triple-negative breast cancer.Willier, S. ; Unland, R. ; Janik, D. ; Neff, F. ; da Costa, O.P. ; Dirksen, U. ; Butt, E. ; Grunewald, T.G. ; Burdach, S. ; Richter, G.
Role of Thyroid Receptor Interacting Protein 6 (TRIP6) in migration and invasion of Ewing' sarcoma cells.Hachmöller, O. ; Buzanich, A.G. ; Aichler, M. ; Radtke, M. ; Dietrich, D. ; Schwamborn, K. ; Lutz, L. ; Werner, M. ; Sperling, M. ; Walch, A.K. ; Karst, U.
Elemental bioimaging and speciation analysis for the investigation of Wilson's disease using μXRF and XANES.Li, J. ; Dawidek, T. ; Liegsalz, V. ; Tzalis, V. ; Feuchtinger, A. ; Avril, S.
Intratumoral heterogeneity of common protein biomarkers assessed by immunohistochemistry in breast cancer tissues.Dislich, B. ; Stein, A. ; Seiler, C.A. ; Walch, A.K. ; Berezowska, S. ; Zlobec, I. ; Galvan, J.A. ; Langer, R.
Low frequency of epithelial PD-L1 staining in esophageal and other gastrointestinal adenocarcinomas.Ly, A. ; Merl-Pham, J. ; Priller, M. ; Gruhn, F. ; Senninger, N. ; Ueffing, M. ; Hauck, S.M.
Proteomic profiling suggests central role of STAT signaling during retinal degeneration in the rd10 mouse model.Dislich, B. ; Stein, A. ; Seiler, C.A. ; Walch, A.K. ; Berezowska, S. ; Zlobec, I. ; Galvan, J.A. ; Langer, R.
Low frequency of epithelial PD-L1 staining in esophageal and other gastrointestinal adenocarcinomas.Li, J. ; Dawidek, T. ; Liegsalz, V. ; Tzalis, V. ; Feuchtinger, A. ; Avril, S.
Intratumoral heterogeneity of common protein biomarkers assessed by immunohistochemistry in breast cancer tissues.Grüner, B.M. ; Winkelmann, I. ; Feuchtinger, A. ; Sun, N. ; Balluff, B. ; Teichmann, N. ; Herner, A. ; Kalideris, E. ; Steiger, K. ; Braren, R. ; Aichler, M. ; Esposito, I. ; Schmid, R.M. ; Walch, A.K. ; Siveke, J.T.
Modeling therapy response and spatial tissue distribution of erlotinib in pancreatic cancer.Lahiri, S. ; Sun, N. ; Buck, A. ; Imhof, A. ; Walch, A.K.
MALDI imaging mass spectrometry as a novel tool for detecting histone modifications in clinical tissue samples.Falkenberg, N. ; Höfig, I. ; Rosemann, M. ; Szumielewski, J. ; Richter, S. ; Schorpp, K.K. ; Hadian, K. ; Aubele, M. ; Atkinson, M.J. ; Anastasov, N.
Three-dimensional microtissues essentially contribute to preclinical validations of therapeutic targets in breast cancer.Girst, S. ; Greubel, C. ; Reindl, J. ; Siebenwirth, C. ; Zlobinskaya, O. ; Walsh, D.W. ; Ilicic, K. ; Aichler, M. ; Walch, A.K. ; Wilkens, J.J. ; Multhoff, G. ; Dollinger, G. ; Schmid, T.E.
Proton minibeam radiation therapy reduces side effects in an in vivo mouse ear model.Sun, N. ; Fernandez, I.E. ; Wei, M. ; Wu, Y. ; Aichler, M. ; Eickelberg, O. ; Walch, A.K.
Pharmacokinetic and pharmacometabolomic study of pirfenidone in normal mouse tissues using high mass resolution MALDI-FTICR-mass spectrometry imaging.Hensel, T. ; Giorgi, C. ; Schmidt, O. ; Calzada-Wack, J. ; Neff, F. ; Buch, T. ; Niggli, F.K. ; Schäfer, B.W. ; Burdach, S. ; Richter, G.H.
Targeting the EWS-ETS transcriptional program by BET bromodomain inhibition in Ewing sarcoma.Lahiri, S. ; Sun, N. ; Solis-Mezarino, V. ; Fedisch, A. ; Ninkovic, J. ; Feuchtinger, A. ; Götz, M. ; Walch, A.K. ; Imhof, A.
In situ detection of histone variants and modifications in mouse brain using imaging mass spectrometry.Boeckh-Behrens, T. ; Schubert, M.I. ; Forschler, A. ; Prothmann, S. ; Kreiser, K. ; Zimmer, C. ; Riegger, J. ; Bauer, J. ; Neff, F. ; Kehl, V. ; Pelisek, J. ; Schirmer, L. ; Mehr, M. ; Poppert, H.
The impact of histological clot composition in embolic stroke.Leinhäuser, I.
The bone morphogenetic protein 7 (BMP7) plays a pro-tumorigenic role in pheochromocytoma.Aubele, M. ; Huber, M. ; Falkenberg, N. ; Gross, E. ; Braselmann, H. ; Walch, A.K. ; Schmitt, M.
uPA receptor and its interaction partners: Impact as potential therapeutic targets in triple-negative breast cancer.Fernandez, I.E. ; Na, S. ; Wei, M. ; Aichler, M. ; Walch, A.K. ; Eickelberg, O.
In-situ detection of pirfenidone and endogenous metabolites by maldi-imaging mass spectrometry in fibrotic tissue.Notni, J. ; Hofmann, F. ; Steiger, K. ; Reich, D. ; Kapp, T.G. ; Rechenmacher, F. ; Kessler, H. ; Oswald, F. ; Wester, H.-J.
Variation of specific activities of Ga-68-Aquibeprin and Ga-68-Avebetrin enables selective PET-imaging of different alpha(5)beta(1)- und alpha(v)beta(3)-integrin expression densities.Lloyd, K.C.K. ; McKerlie, C. ; Seong, J.K. ; Neff, F.
Comment on "One health, one literature: Weaving together veterinary and medical research".Bönisch, C. ; Irmler, M. ; Brachthäuser, L. ; Neff, F. ; Bamberger, M.T. ; Marschall, S. ; Hrabě de Angelis, M. ; Beckers, J.
Dexamethasone treatment alters insulin, leptin, and adiponectin levels in male mice as observed in DIO but does not lead to alterations of metabolic phenotypes in the offspring.Kovac, M. ; Blattmann, C. ; Ribi, S. ; Smida, J. ; Müller, N.S. ; Engert, F. ; Castro-Giner, F. ; Weischenfeldt, J. ; Kovacova, M. ; Krieg, A. ; Andreou, D. ; Tunn, P.U. ; Dürr, H.R. ; Rechl, H.P. ; Schaser, K.D. ; Melcher, I. ; Burdach, S. ; Kulozik, A. ; Specht, K. ; Heinimann, K. ; Fulda, S. ; Bielack, S. ; Jundt, G. ; Tomlinson, I. ; Korbel, J.O. ; Nathrath, M. ; Baumhoer, D.
Exome sequencing of osteosarcoma reveals mutation signatures reminiscent of BRCA deficiency.Habringer, S. ; Li, Z. ; Pietschmann, E. ; Slawska, J. ; Walch, A.K. ; Peschel, C. ; Keller, U.
Very early functional in-vivo imaging to predict response to B cell receptor pathway targeting in lymphoma.Naves, L.A. ; Daly, A.F. ; Dias, L.A. ; Yuan, B. ; Zakir, J.C. ; Barra, G.B. ; Palmeira, L. ; Villa, C. ; Trivellin, G. ; Júnior, A.J. ; Neto, F.F. ; Liu, P.P. ; Pellegata, N.S. ; Stratakis, C.A. ; Lupski, J.R. ; Beckers, A.
Aggressive tumor growth and clinical evolution in a patient with X-linked acro-gigantism syndrome.Upheber, S.
Die Integrin αvβ3-vermittelte Migration humaner Ovarialkarzinomzellen als Funktion des Metastasierungssuppressors KAI1 (CD82) und seiner Splice-Variante sowie deren Interaktion mit dem Zell/Zell-Adhäsionsmolekül E-Cadherin.Wiedemann, T. ; Bielohuby, M. ; Müller, T.D. ; Bidlingmaier, M. ; Pellegata, N.S.
Obesity in MENX rats is accompanied by high circulating levels of ghrelin and improved insulin sensitivity.Nathrath, M. ; Smida, J. ; Baumhoer, D. ; Kovac, M.
The genomic landscape in osteosarcoma.Kempf, S.J. ; Sepe, S. ; von Toerne, C. ; Janik, D. ; Neff, F. ; Hauck, S.M. ; Atkinson, M.J. ; Mastroberardino, P.G. ; Tapio, S.
Neonatal irradiation leads to persistent proteome alterations involved in synaptic plasticity in the mouse hippocampus and cortex.Chekkoury, A. ; Gateau, J. ; Driessen, W.H.P. ; Symvoulidis, P. ; Bézière, N. ; Feuchtinger, A. ; Walch, A.K. ; Ntziachristos, V.
Optical mesoscopy without the scatter: Broadband multispectral optoacoustic mesoscopy.Pfluger, P.T. ; Kabra, D.G. ; Aichler, M. ; Schriever, S.C. ; Pfuhlmann, K. ; Casquero García, V. ; Lehti, M. ; Weber, J. ; Kutschke, M. ; Rozman, J. ; Elrod, J.W. ; Hevener, A.L. ; Feuchtinger, A. ; Hrabě de Angelis, M. ; Walch, A.K. ; Rollmann, S.M. ; Aronow, B.J. ; Müller, T.D. ; Perez-Tilve, D. ; Jastroch, M. ; de Luca, M. ; Molkentin, J.D. ; Tschöp, M.H.
Calcineurin links mitochondrial elongation with energy metabolism.Leinhäuser, I. ; Richter, A. ; Lee, M.S. ; Höfig, I. ; Anastasov, N. ; Fend, F. ; Ercolino, T. ; Mannelli, M. ; Gimenez-Roqueplo, A.P. ; Robledo, M. ; de Krijger, R.R. ; Beuschlein, F. ; Atkinson, M.J. ; Pellegata, N.S.
Oncogenic features of the Bone Morphogenic Protein 7 (BMP7) in pheochromocytoma.Ratschiller, T. ; Deutsch, M.A. ; Calzada-Wack, J. ; Neff, F. ; Roesch, C. ; Guenzinger, R. ; Lange, R. ; Krane, M.
Heterotopic cervical heart transplantation in mice.Lagouge, M. ; Mourier, A. ; Lee, H.J. ; Spåhr, H. ; Wai, T. ; Kukat, C. ; Silva Ramos, E. ; Motori, E. ; Busch, J.D. ; Siira, S. ; German Mouse Clinic Consortium (Larsson, N.G. ; Aguilar-Pimentel, J.A. ; Amarie, O.V. ; Becker, L. ; Beckers, J. ; Brachthäuser, L. ; Calzada-Wack, J. ; Eickelberg, O. ; Gailus-Durner, V. ; Garrett, L. ; Graw, J. ; Hans, W. ; Hölter, S.M. ; Horsch, M. ; Hrabě de Angelis, M. ; Janik, D. ; Klein-Rodewald, T. ; Lengger, C. ; Leuchtenberger, S. ; Maier, H. ; Moreth, K. ; Neff, F. ; Östereicher, M.A. ; Puk, O. ; Rácz, I. ; Rathkolb, B. ; Rozman, J. ; Steinkamp, R. ; Stoeger, C. ; Stöger, T. ; Vernaleken, A. ; Wurst, W. ; Yildirim, A.Ö. ; Zimprich, A.) ; Kremmer, E. ; Filipovska, A.
SLIRP regulates the rate of mitochondrial protein synthesis and protects LRPPRC from degradation.Hrabě de Angelis, M. ; Nicholson, G. ; Selloum, M. ; White, J.K. ; Morgan, H. ; Ramirez-Solis, R. ; Sorg, T. ; Wells, S. ; Fuchs, H. ; Fray, M. ; Adams, D.J. ; Adams, N.C. ; Adler, T. ; Aguilar-Pimentel, J.A. ; Ali-Hadji, D. ; Amann, G. ; André, P. ; Atkins, S. ; Auburtin, A. ; Ayadi, A. ; Becker, J. ; Becker, L. ; Bedu, E. ; Bekeredjian, R. ; Birling, M.C. ; Blake, A. ; Bottomley, J. ; Bowl, M.R. ; Brault, V. ; Busch, D.H. ; Bussell, J.N. ; Calzada-Wack, J. ; Cater, H. ; Champy, M.F. ; Charles, P. ; Chevalier, C. ; Chiani, F. ; Codner, G.F. ; Combe, R. ; Cox, R.D. ; Dalloneau, E. ; Dierich, A. ; di Fenza, A. ; Doe, B. ; Duchon, A. ; Eickelberg, O. ; Esapa, C.T. ; Fertak, L.E. ; Feigel, T. ; Emelyanova, I. ; Estabel, J. ; Favor, J. ; Flenniken, A.M. ; Gambadoro, A. ; Garrett, L. ; Gates, H. ; Gerdin, A.K. ; Gkoutos, G.V. ; Greenaway, S. ; Glasl, L. ; Goetz, P. ; da Cruz, I.G. ; Götz, A. ; Graw, J. ; Guimond, A. ; Hans, W. ; Hicks, G. ; Hölter, S.M. ; Höfler, H. ; Hancock, J.M. ; Hoehndorf, R. ; Hough, T. ; Houghton, R. ; Hurt, A. ; Ivandic, B. ; Jacobs, H. ; Jacquot, S. ; Jones, N. ; Karp, N.A. ; Katus, H.A. ; Kitchen, S. ; Klein-Rodewald, T. ; Klingenspor, M. ; Klopstock, T. ; Lalanne, V. ; Leblanc, S. ; Lengger, C. ; le Marchand, E. ; Ludwig, T. ; Lux, A. ; McKerlie, C. ; Maier, H. ; Mandel, J.L. ; Marschall, S. ; Mark, M. ; Melvin, D.G. ; Meziane, H. ; Micklich, K. ; Mittelhauser, C. ; Monassier, L. ; Moulaert, D. ; Müller, S. ; Naton, B. ; Neff, F. ; Nolan, P.M. ; Nutter, L.M. ; Ollert, M. ; Pavlovic, G. ; Pellegata, N.S. ; Peter, E. ; Petit-Demoulière, B. ; Pickard, A. ; Podrini, C. ; Potter, P. ; Pouilly, L. ; Puk, O. ; Richardson, D. ; Rousseau, S. ; Quintanilla-Fend, L. ; Quwailid, M.M. ; Rácz, I. ; Rathkolb, B. ; Riet, F. ; Rossant, J. ; Roux, M. ; Rozman, J. ; Ryder, E. ; Salisbury, J. ; Santos, L. ; Schäble, K.-H. ; Schiller, E. ; Schrewe, A. ; Schulz, H. ; Steinkamp, R. ; Simon, M. ; Stewart, M. ; Stoeger, C. ; Stöger, T. ; Sun, M. ; Sunter, D. ; Teboul, L. ; Tilly, I. ; Tocchini-Valentini, G.P. ; Tost, M. ; Treise, I. ; Vasseur, L. ; Velot, E. ; Vogt Weisenhorn, D.M. ; Wagner, C. ; Walling, A. ; Wattenhofer-Donze, M. ; Weber, B. ; Wendling, O. ; Westerberg, H. ; Willershäuser, M. ; Wolf, E. ; Wolter, A. ; Wood, J. ; Wurst, W. ; Yildirim, A.Ö. ; Zeh, R. ; Zimmer, A. ; Zimprich, A. ; Holmes, C. ; Steel, K.P. ; Herault, Y. ; Gailus-Durner, V. ; Mallon, A.M. ; Brown, S.D.
Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics.Kiermayer, C. ; Northrup, E. ; Schrewe, A. ; Walch, A.K. ; Hrabě de Angelis, M. ; Schoensiegel, F. ; Zischka, H. ; Prehn, C. ; Adamski, J. ; Bekeredjian, R. ; Ivandic, B. ; Kupatt, C. ; Brielmeier, M.
Heart-specific knockout of the mitochondrial Thioredoxin reductase (Txnrd2) induces metabolic and contractile dysfunction in the aging myocardium.Wiedemann, T. ; Pellegata, N.S.
Animal models of multiple endocrine neoplasia.Huber, M. ; Falkenberg, N. ; Gross, E. ; Mall, R. ; Braselmann, H. ; Schmitt, M. ; Aubele, M.
The impact of the uPAR system and its interaction partners as potential therapeutic targets in TNBC.Deppisch, N. ; Ruf, P. ; Eissler, N. ; Neff, F. ; Buhmann, R. ; Lindhofer, H. ; Mocikat, R.
Efficacy and tolerability of a GD2-directed trifunctional bispecific antibody in a preclinical model: Subcutaneous administration is superior to intravenous delivery.Maugg, D. ; Rothenaigner, I. ; Schorpp, K.K. ; Potukuchi, H.K. ; Korsching, E. ; Baumhoer, D. ; Hadian, K. ; Smida, J. ; Nathrath, M.
New small molecules targeting apoptosis and cell viability in osteosarcoma.Keipert, S. ; Kutschke, M. ; Lamp, D. ; Brachthäuser, L. ; Neff, F. ; Meyer, C.W. ; Oelkrug, R. ; Kharitonenkov, A. ; Jastroch, M.
Genetic disruption of uncoupling protein 1 in mice renders brown adipose tissue a significant source of FGF21 secretion.Berchtold, S.
Epithelial-stromal interaction in pancreatic cancer: The role of collagen type V.Groß, C. ; Steiger, K. ; Sayyed, S. ; Heid, I. ; Feuchtinger, A. ; Walch, A.K. ; Hess J. ; Unger, K. ; Zitzelsberger, H. ; Settles, M. ; Schlitter, A.M. ; Dworniczak, J. ; Altomonte, J. ; Ebert, O. ; Schwaiger, M. ; Rummeny, E.J. ; Steingötter, A. ; Esposito, I. ; Braren, R.
Model matters: Differences in orthotopic rat hepatocellular carcinoma physiology determine therapy response to sorafenib.Notni, J. ; Hofman, F. ; Steiger, K. ; Reich, D. ; Kapp, T.G. ; Rechenmacher, F. ; Kessler, H. ; Wester, H.J.
Ga-68-Aquibeprin and Ga-68-Avebetrin for complementary, selective PET imaging of integrin subtypes alpha(5)beta(1) and alpha(v)beta(3).Velikova, V.B. ; Müller, C. ; Ghirardo, A. ; Rock, T. ; Aichler, M. ; Walch, A.K. ; Schmitt-Kopplin, P. ; Schnitzler, J.-P.
Knocking down of isoprene emission modifies the lipid matrix of thylakoid membranes and influences the chloroplast ultrastructure in poplar.Buck, A. ; Ly, A. ; Balluff, B. ; Sun, N. ; Gorzolka, K. ; Feuchtinger, A. ; Janssen, K.P. ; Kuppen, P.J. ; van de Velde, C.J. ; Weirich, G. ; Erlmeier, F. ; Langer, R. ; Aubele, M. ; Zitzelsberger, H. ; Aichler, M. ; Walch, A.K.
High-resolution MALDI-FT-ICR MS imaging for the analysis of metabolites from formalin-fixed paraffin-embedded clinical tissue samples.Bauer, L. ; Takacs, A. ; Slotta-Huspenina, J. ; Langer, R. ; Becker, K. ; Novotny, A. ; Ott, K. ; Walch, A.K. ; Hapfelmeier, A. ; Keller, G.
Clinical significance of NOTCH1 and NOTCH2 expression in gastric carcinomas: An immunohistochemical study.Schöllnberger, H. ; Ozasa, K. ; Neff, F. ; Kaiser, J.C.
Cardiovascular disease mortality of a-bomb survivors and the healthy survivor selection effect.Erlmeier, F. ; Feuchtinger, A. ; Borgmann, D.M. ; Rudelius, M. ; Autenrieth, M. ; Walch, A.K. ; Weirich, G.
Supremacy of modern morphometry in typing renal oncocytoma and malignant look-alikes.Ingold, I. ; Aichler, M. ; Yefremova, E. ; Roveri, A. ; Buday, K. ; Doll, S. ; Tasdemir, A. ; Hoffard, N. ; Wurst, W. ; Walch, A.K. ; Ursini, F. ; Friedmann Angeli, J.P.F. ; Conrad, M.
Expression of a catalytically inactive mutant form of Glutathione peroxidase 4 (Gpx4) confers a dominant-negative effect in male fertility.Oetjen, J. ; Veselkov, K. ; Watrous, J. ; McKenzie, J.S. ; Becker, M. ; Hauberg-Lotte, L. ; Kobarg, J.H. ; Strittmatter, N. ; Mróz, A.K. ; Hoffmann, F. ; Trede, D. ; Palmer, A. ; Schiffler, S. ; Steinhorst, K. ; Aichler, M. ; Goldin, R. ; Guntinas-Lichius, O. ; von Eggeling, F. ; Thiele, H. ; Maedler, K. ; Walch, A.K. ; Maass, P. ; Dorrestein, P.C. ; Takats, Z. ; Alexandrov, T.
Benchmark datasets for 3D MALDI- and DESI-imaging mass spectrometry.Almstätter, I. ; Mykhaylyk, O. ; Settles, M. ; Altomonte, J. ; Aichler, M. ; Walch, A.K. ; Rummeny, E.J. ; Ebert, O. ; Plank, C. ; Braren, R.
Characterization of magnetic viral complexes for targeted delivery in oncology.van Berkel, A. ; Upendrao, J. ; Lenders, J. ; Pellegata, N.S. ; Kusters, B. ; Piscaer, I. ; Hermus, A.R. ; Plantinga, T.S. ; Langenhuijsen, H. ; Vriens, D. ; Janssen, M. ; Gotthardt, M. ; Timmers, H.
Semi-quantitative 123I-metaiodobenzylguanidine scintigraphy to distinguish pheochromocytoma and paraganglioma from physiological adrenal uptake and its correlation with genotype-dependent expression of catecholamine transporters.Genitsch, V. ; Novotny, A. ; Seiler, C.A. ; Kröll, D. ; Walch, A.K. ; Langer, R.
Epstein-Barr virus in gastro-esophageal adenocarcinomas - single center experiences in the context of current literature.Poos, K. ; Smida, J. ; Maugg, D. ; Eckstein, G.N. ; Baumhoer, D. ; Nathrath, M. ; Korsching, E.
Genomic heterogeneity of osteosarcoma - shift from single candidates to functional modules.Aichler, M. ; Walch, A.K.
MALDI Imaging mass spectrometry: Current frontiers and perspectives in pathology research and practice.Ribi, S. ; Baumhoer, D. ; Lee, K. ; Edison ; Teo, A.S. ; Madan, B. ; Zhang, K. ; Kohlmann, W.K. ; Yao, F. ; Lee, W.H. ; Hoi, Q. ; Cai, S.W. ; Woo, X.Y. ; Tan, P.L. ; Jundt, G. ; Smida, J. ; Nathrath, M. ; Sung, W.K. ; Schiffman, J.D. ; Virshup, D.M. ; Hillmer, A.M.
TP53 intron 1 hotspot rearrangements are specific to sporadic osteosarcoma and can cause Li-Fraumeni syndrome.Azimzadeh, O. ; Sievert, W. ; Sarioglu, H. ; Merl-Pham, J. ; Yentrapalli, R. ; Bakshi, M.V. ; Janik, D. ; Ueffing, M. ; Atkinson, M.J. ; Multhoff, G. ; Tapio, S.
Integrative proteomics and targeted transcriptomics analyses in cardiac endothelial cells unravel mechanisms of long-term radiation-induced vascular dysfunction.Lee, M.S. ; Wiedemann, T. ; Gross, C. ; Leinhäuser, I. ; Roncaroli, F. ; Braren, R. ; Pellegata, N.S.
Targeting PI3K/mTOR signaling displays potent antitumor efficacy against nonfunctioning pituitary adenomas.Hellfritsch, J. ; Kirsch, J. ; Schneider, M. ; Fluege, T. ; Wortmann, M. ; Frijhoff, J. ; Dagnell, M. ; Fey, T. ; Esposito, I. ; Kölle, P. ; Pogoda, K. ; Ingold, I. ; Friedmann Angeli, J.P.F. ; Kuhlencordt, P. ; Östman, A. ; Pohl, U. ; Beck, H. ; Conrad, M.
Knockout of mitochondrial thioredoxin reductase stabilizes prolyl hydroxylase 2 and inhibits tumor growth and tumor-derived angiogenesis.Schmitt, S. ; Eberhagen, C. ; Weber, S. ; Aichler, M. ; Zischka, H.
Isolation of mitochondria from cultured cells and liver tissue biopsies for molecular and biochemical analyses.Schulz, S. ; Lichtmannegger, J. ; Schmitt, S. ; Leitzinger, C. ; Eberhagen, C. ; Einer, C. ; Kerth, J. ; Aichler, M. ; Zischka, H.
A protocol for the parallel isolation of intact mitochondria from rat liver, kidney, heart, and brain.Wester, H.J. ; Keller, U. ; Schottelius, M. ; Beer, A. ; Philipp-Abbrederis, K. ; Hoffmann, F. ; Simecek, J. ; Gerngross, C. ; Lassmann, M. ; Herrmann, K. ; Pellegata, N.S. ; Rudelius, M. ; Kessler, H. ; Schwaiger, M.
Disclosing the CXCR4 expression in lymphoproliferative diseases by targeted molecular imaging.Beckers, A. ; Lodish, M. ; Giampaolo, T. ; Rostomyan, L. ; Lee, M.S. ; Faucz, F.R. ; Yuan, B. ; Choong, C. ; Caberg, J.H. ; Verrua, E. ; Naves, L.A. ; Cheetham, T. ; Young, J. ; Lysy, P. ; Petrossians, P. ; Cotterill, A. ; Shah, N. ; Metzger, D. ; Castermans, E. ; Ambrosio, M.R. ; Villa, C. ; Strebkova, N. ; Mazerkina, N. ; Gaillard, S. ; Barcelos Barra, G. ; Casulari, L.A. ; Neggers, S. ; Salvatori, R. ; Jaffrain-Rea, M.L. ; Zacharin, M. ; Lecumberri Santamaria, B. ; Zacharieva, S. ; Lim, E.M. ; Mantovani, G. ; Zatelli, M.C. ; Collins, M.T. ; Bonneville, J.F. ; Quezado, M.M. ; Chittiboina, P. ; Oldfield, E. ; Bours, V. ; Liu, P. ; de Herder, W.W. ; Pellegata, N.S. ; Lupski, J.R. ; Daly, A.F. ; Stratakis, C.A.
X-Linked Acrogigantism (X-LAG) syndrome: Clinical profile and therapeutic responses.Kessler, T. ; Zhang, L. ; Liu, Z. ; Yin, X. ; Huang, Y. ; Wang, Y. ; Fu, Y. ; Mayr, M. ; Ge, Q. ; Xu, Q. ; Zhu, Y. ; Wang, X. ; Schmidt, K.J. ; de Wit, C. ; Erdmann, J. ; Schunkert, H. ; Aherrahrou, Z ; Kong, W. ; German Mouse Clinic Consortium (Adamski, J. ; Adler, T. ; Aguilar-Pimentel, J.A. ; Amarie, O.V. ; Becker, L. ; Beckers, J. ; Brachthäuser, L. ; Busch, D.H. ; Calzada-Wack, J. ; Eickelberg, O. ; Fuchs, H. ; Gailus-Durner, V. ; Garrett, L. ; Graw, J. ; Hans, W. ; Hölter, S.M. ; Horsch, M. ; Hrabě de Angelis, M. ; Janik, D. ; Klein-Rodewald, T. ; Klingenspor, M. ; Klopstock, T. ; Lengger, C. ; Leuchtenberger, S. ; Maier, H. ; Moreth, K. ; Neff, F. ; Ollert, M. ; Prehn, C. ; Puk, O. ; Rathkolb, B. ; Rozman, J. ; Steinkamp, R. ; Stoeger, C. ; Stöger, T. ; Vernaleken, A. ; Yildirim, A.Ö. ; Wurst, W. ; Zimprich, A.)
ADAMTS-7 inhibits re-endothelialization of injured arteries and promotes vascular remodeling via cleavage of thrombospondin-1.Aubele, M.
Genetik für Ahnungslose : Eine Einstiegshilfe für Studierende.Aichler, M. ; Huber, K. ; Schilling, F. ; Lohöfer, F. ; Kosanke, K. ; Meier, R. ; Rummeny, E.J. ; Walch, A.K. ; Wildgruber, M.
Spatially resolved quantification of Gadolinium(III)-based magnetic resonance agents in tissue by MALDI imaging mass spectrometry after in vivo MRI.Sambugaro, S. ; di Ruvo, M. ; Ambrosio, M.R. ; Pellegata, N.S. ; Bellio, M. ; Guerra, A. ; Buratto, M. ; Foschini, M.P. ; Tagliati, F. ; degli Uberti, E.C. ; Zatelli, M.C.
Early onset acromegaly associated with a novel deletion in CDKN1B 5'UTR region.Falkenberg, N. ; Anastasov, N. ; Schaub, A. ; Radulovic, V. ; Schmitt, M. ; Magdolen, V. ; Aubele, M.
Secreted uPAR isoform 2 (uPAR7b) is a novel direct target of miR-221.Bi, Z. ; Merl-Pham, J. ; Uehlein, N. ; Zimmer, I. ; Mühlhans, S. ; Aichler, M. ; Walch, A.K. ; Kaldenhoff, R. ; Palme, K. ; Schnitzler, J.-P. ; Block, K.
RNAi-mediated downregulation of poplar Plasma membrane Intrinsic Proteins (PIPs) changes plasma membrane proteome composition and affects leaf physiology.Vukicevic, V. ; Rubin de Celis, M.F. ; Pellegata, N.S. ; Bornstein, S.R. ; Androutsellis-Theotokis, A. ; Ehrhart-Bornstein, M.
Adrenomedullary progenitor cells: Isolation and characterization of a multi-potent progenitor cell population.Miras, A. ; Mogford, J.T. ; Wright, J.E. ; Mendoza, N.N. ; Xekouki, P. ; Lakhani, A. ; Pellegata, N.S. ; Stratakis, C.A. ; Roncaroli, F. ; Russell-Jones, D.L.
Ovarian hyperstimulation from ectopic hypersecretion of follicle stimulating hormone.Singh, S.K. ; Chen, N.M. ; Hessmann, E. ; Siveke, J. ; Lahmann, M. ; Singh, G. ; Voelker, N. ; Vogt, S. ; Esposito, I. ; Schmidt, A. ; Brendel, C. ; Stiewe, T. ; Gaedcke, J. ; Merenberger, M. ; Crawford, H.C. ; Bamlet, W.R. ; Zhang, J.S. ; Li, X.K. ; Smyrk, T.C. ; Billadeau, D.D. ; Hebrok, M. ; Neesse, A. ; Koenig, A. ; Ellenrieder, V.
Antithetical NFATc1-Sox2 and p53-miR200 signaling networks govern pancreatic cancer cell plasticity.Teiluf, K. ; Seidl, C. ; Blechert, B. ; Gaertner, F.C. ; Gilbertz, K.P. ; Fernandez, V. ; Bassermann, F. ; Endell, J. ; Boxhammer, R. ; Leclair, S. ; Vallon, M. ; Aichler, M. ; Feuchtinger, A. ; Bruchertseifer, F. ; Morgenstern, A. ; Essler, M.
α-Radioimmunotherapy with 213Bi-anti-CD38 immunoconjugates is effective in a mouse model of human multiple myeloma.Chin, S.O. ; Hwang, J.K. ; Rhee, S.Y. ; Chon, S. ; Oh, S.S. ; Lee, M.S. ; Pellegata, N.S. ; Kim, S.W.
Acromegaly due to a macroinvasive plurihormonal pituitary adenoma and a rectal carcinoid tumor.Helmbrecht, M.S. ; Soellner, H. ; Truckenbrodt, A.M. ; Sundermeier, J. ; Cohrs, C.M. ; Hans, W. ; Hrabě de Angelis, M. ; Feuchtinger, A. ; Aichler, M. ; Fouad, K. ; Huber, A.B.
Loss of Npn1 from motor neurons causes postnatal deficits independent from Sema3A signaling.Diakopoulos, K.N. ; Lesina, M. ; Wörmann, S. ; Song, L. ; Aichler, M. ; Schild, L. ; Artati, A. ; Römisch-Margl, W. ; Wartmann, T. ; Fischer, R. ; Kabiri, Y. ; Zischka, H. ; Halangk, W. ; Demir, I.E. ; Pilsak, C. ; Walch, A.K. ; Mantzoros, C.S. ; Steiner, J.M. ; Erkan, M. ; Schmid, R.M. ; Witt, H. ; Adamski, J. ; Algül, H.
Impaired autophagy induces chronic atrophic pancreatitis in mice via sex- and nutrition-dependent processes.Ly, A. ; Schöne, C. ; Becker, M. ; Rattke, J. ; Meding, S. ; Aichler, M. ; Suckau, D. ; Walch, A.K. ; Hauck, S.M. ; Ueffing, M.
High-resolution MALDI mass spectrometric imaging of lipids in the mammalian retina.Lee, M.S. ; Lupp, A. ; Mendoza, N.M. ; Martin, N.M. ; Beschorner, R. ; Honegger, J. ; Schlegel, J. ; Shively, T. ; Pulz, E. ; Schulz, S. ; Roncaroli, F. ; Pellegata, N.S.
SSTR3 is a putative target for the medical treatment of gonadotroph adenomas of the pituitary.McDonnell, L.A. ; Römpp, A. ; Balluff, B.D. ; Heeren, R.M.A. ; Albar, J.P. ; Andrén, P.E. ; Corthals, G.L. ; Walch, A.K. ; Stoeckli, M.
Discussion point: Reporting guidelines for mass spectrometry imaging.Ermolayev, V. ; Mohajerani, P. ; Ale, A.B.F ; Sarantopoulos, A. ; Aichler, M. ; Kayser, G. ; Walch, A.K. ; Ntziachristos, V.
Early recognition of lung cancer by integrin targeted imaging in K-ras mouse model.Berchtold, S. ; Grünwald, B. ; Krüger, A. ; Reithmeier, A. ; Hähl, T. ; Cheng, T. ; Feuchtinger, A. ; Born, D. ; Erkan, M. ; Kleeff, J. ; Esposito, I.
Collagen type V promotes the malignant phenotype of pancreatic ductal adenocarcinoma.Pardi, E. ; Mariotti, S. ; Pellegata, N.S. ; Benfini, K. ; Borsari, S. ; Saponaro, F. ; Torregrossa, L. ; Cappai, A. ; Satta, C. ; Mastinu, M. ; Marcocci, C. ; Cetani, F.
Functional characterization of a CDKN1B mutation in a Sardinian kindred with Multiple Endocrine Neoplasia type 4 (MEN4).Kahle-Stephan, M. ; Schäfer, A. ; Seelig, A. ; Schultheiß, J. ; Wu, M. ; Aichler, M. ; Leonhardt, J. ; Rathkolb, B. ; Rozman, J. ; Sarioglu, H. ; Hauck, S.M. ; Ueffing, M. ; Wolf, E. ; Kastenmüller, G. ; Adamski, J. ; Walch, A.K. ; Hrabě de Angelis, M. ; Neschen, S.
High fat diet-induced modifications in membrane lipid and mitochondrial-membrane protein signatures precede the development of hepatic insulin resistance in mice.Buck, A. ; Halbritter, S. ; Späth, C. ; Feuchtinger, A. ; Aichler, M. ; Zitzelsberger, H. ; Janssen, K.P. ; Walch, A.K.
Distribution and quantification of irinotecan and its active metabolite SN-38 in colon cancer murine model systems using MALDI MSI.Keeney, J.G. ; O'Bleness, M.S. ; Anderson, N. ; Davis, J.M. ; Arevalo, N. ; Busquet, N. ; Chick, W. ; Rozman, J. ; Hölter, S.M. ; Garrett, L. ; Horsch, M. ; German Mouse Clinic Consortium (Adler, T. ; Aguilar-Pimentel, J.A. ; Amarie, O.V. ; Eickelberg, O. ; Gailus-Durner, V. ; Graw, J. ; Hans, W. ; Horsch, M. ; Janik, D. ; Neff, F. ; Ollert, M. ; Puk, O. ; Rácz, I. ; Rathkolb, B. ; Stöger, T. ; Yildirim, A.Ö.) ; Beckers, J. ; Wurst, W. ; Klingenspor, M. ; Restrepo, D. ; Sikela, J.M. ; Hrabě de Angelis, M.
Generation of mice lacking DUF1220 protein domains: Effects on fecundity and hyperactivity.Schenck, T.L. ; Stewart, J. ; Lin, S. ; Aichler, M. ; Machens, H.G. ; Giunta, R.E.
Anatomical and histomorphometric observations on the transfer of the anterior interosseous nerve to the deep branch of the ulnar nerve.Selmansberger, M. ; Feuchtinger, A. ; Zurnadzhy, L. ; Michna, A. ; Kaiser, J.C. ; Abend, M. ; Brenner, A. ; Bogdanova, T. ; Walch, A.K. ; Unger, K. ; Zitzelsberger, H. ; Hess J.
CLIP2 as radiation biomarker in papillary thyroid carcinoma.Falkenberg, N. ; Anastasov, N. ; Höfig, I. ; Bashkueva, K. ; Lindner, K. ; Höfler, H. ; Rosemann, M. ; Aubele, M.
Additive impact of HER2-/PTK6-RNAi on interactions with HER3 or IGF-1R leads to reduced breast cancer progression in vivo.Baumgart, A. ; Mazur, P.K. ; Anton, M. ; Rudelius, M. ; Schwamborn, K. ; Feuchtinger, A. ; Behnke, K. ; Walch, A.K. ; Braren, R. ; Peschel, C. ; Duyster, J. ; Siveke, J.T. ; Dechow, T.
Opposing role of Notch1 and Notch2 in a KrasG12D-driven murine non-small cell lung cancer model.Leinhäuser, I. ; Höfig, I. ; Anastasov, N. ; Beuschlein, F. ; Mannelli, M. ; Atkinson, M.J. ; Pellegata, N.S.
The Bone morphogenic protein 7 (Bmp7) plays a pro-tumorigenic role in pheochromocytoma.Kandemir, M. ; Feuchtinger, A. ; Walch, A.K. ; Hamprecht, F.A.
Digital pathology: Multiple instance learning can detect Barrett's cancer.Huber, M. ; Falkenberg, N. ; Schmitt, M. ; Braselmann, H. ; Mall, R. ; Jakovac, M. ; Walch, A.K. ; Höfler, H. ; Aubele, M.
uPAR and its interaction partners: potential new therapy targets in triple negative breast cancer.Selmansberger, M. ; Feuchtinger, A. ; Zurnadzhy, L. ; Höfig, I. ; Bogdanova, T. ; Walch, A.K. ; Unger, K. ; Zitzelsberger, H. ; Hess J.
CLIP2 as radiation biomarker in papillary thyroid carcinoma.Höfig, I. ; Falkenberg, N. ; Rosemann, M. ; Szumielewski, J. ; Richter, S. ; Atkinson, M.J. ; Aubele, M. ; Anastasov, N.
Relevance of 3D-microtissues to investigate the therapeutic oncogenes HER2 and PTK6 in breast cancer.Pellegata, N.S. ; Molatore, S. ; Neff, F. ; Irmler, M. ; Pulz, E. ; Roncaroli, F.
p27 is a haploinsufficient tumor suppressor in MENX rats and this associates with the development of invasive medullary thyroid carcinoma.Lee, M.S. ; Gaertner, F.C. ; Pellegata, N.S.
Regulation of norepinephrine transporter expression in pheochromocytoma by dual PI3K/mTOR inhibition.Leinhäuser, I. ; Atkinson, M.J. ; Pellegata, N.S.
The transcription factor Phox2a plays a pro-tumorigenic role in pheochromocytoma.Becker, L. ; Kling, E. ; Schiller, E. ; Zeh, R. ; Schrewe, A. ; Hölter, S.M. ; Mossbrugger, I. ; Calzada-Wack, J. ; Strecker, V. ; Wittig, I. ; Dumitru, I. ; Wenz, T. ; Bender, A. ; Aichler, M. ; Janik, D. ; Neff, F. ; Walch, A.K. ; Quintanilla-Fend, L. ; Floß, T. ; Bekeredjian, R. ; Gailus-Durner, V. ; Fuchs, H. ; Wurst, W. ; Meitinger, T. ; Prokisch, H. ; Hrabě de Angelis, M. ; Klopstock, T.
MTO1-deficient mouse model mirrors the human phenotype showing complex I defect and cardiomyopathy.Maier, S.K.
Towards comprehensive identification of proteins from MALDI imaging.Kempf, S.J. ; Casciati, A. ; Buratovic, S. ; Janik, D. ; von Toerne, C. ; Ueffing, M. ; Neff, F. ; Mörtl, S. ; Stenerlöw, B. ; Saran, A. ; Atkinson, M.J. ; Eriksson, P. ; Pazzaglia, S. ; Tapio, S.
The cognitive defects of neonatally irradiated mice are accompanied by changed synaptic plasticity, adult neurogenesis and neuroinflammation.Stering, K.
Etablierung der PLA-Technik an Paraffingewebe von Mammakarzinomen: Identifizierung von PTK6 co-exprimierten Proteinen und ihre medizinische Relevanz.Friedmann Angeli, J.P.F. ; Schneider, M. ; Proneth, B. ; Tyurina, Y.Y. ; Tyurin, V.A. ; Hammond, V.J. ; Herbach, N. ; Aichler, M. ; Walch, A.K. ; Eggenhofer, E. ; Basavarajappa, D. ; Rådmark, O. ; Kobayashi, S. ; Seibt, T. ; Beck, H. ; Neff, F. ; Esposito, I. ; Wanke, R. ; Förster, H. ; Yefremova, O. ; Heinrichmeyer, M. ; Bornkamm, G.W. ; Geissler, E.K. ; Thomas, S.B. ; Stockwell, B.R. ; O'Donnell, V.B. ; Kagan, V.E. ; Schick, J. ; Conrad, M.
Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice.Baumgart, S. ; Chen, N. ; Siveke, J.T. ; König, A.O. ; Zhang, J. ; Singh, S.K. ; Wolf, E. ; Bartkuhn, M. ; Esposito, I. ; Heßmann, E. ; Reinecke, J. ; Nikorowitsch, J. ; Brunner, M. ; Singh, G.P. ; Fernández-Zapico, M.E. ; Smyrk, T.C. ; Bamlet, W.R. ; Eilers, M. ; Neeße, A. ; Gress, T.M. ; Billadeau, D.D. ; Tuveson, D.A. ; Urrutia, R.A. ; Ellenrieder, V.
Inflammation-induced NFATc1-STAT3 transcription complex promotes pancreatic cancer initiation by KrasG12D.Thor, T. ; Künkele, A. ; Pajtler, K.W. ; Wefers, A.K. ; Stephan, H. ; Mestdagh, P. ; Heukamp, L. ; Hartmann, W. ; Vandesompele, J. ; Sadowski, N. ; Becker, L. ; Garrett, L. ; Hölter, S.M. ; Horsch, M. ; Calzada-Wack, J. ; Klein-Rodewald, T. ; Rácz, I. ; Zimmer, A. ; Beckers, J. ; Neff, F. ; Klopstock, T. ; de Antonellis, P. ; Zollo, M. ; Wurst, W. ; Fuchs, H. ; Gailus-Durner, V. ; Schüller, U. ; Hrabě de Angelis, M. ; Eggert, A. ; Schramm, A. ; Schulte, J.H.
MiR-34a deficiency accelerates medulloblastoma formation in vivo.Keller, J. ; Catala-Lehnen, P. ; Huebner, A.K. ; Jeschke, A. ; Heckt, T. ; Lueth, A. ; Krause, M. ; Koehne, T. ; Albers, J. ; Schulze, J. ; Schilling, S. ; Haberland, M. ; Denninger, H. ; Neven, M. ; Hermans-Borgmeyer, I. ; Streichert, T. ; Breer, S. ; Barvencik, F. ; Levkau, B. ; Rathkolb, B. ; Wolf, E. ; Calzada-Wack, J. ; Neff, F. ; Gailus-Durner, V. ; Fuchs, H. ; Hrabě de Angelis, M. ; Klutmann, S. ; Tsourdi, E. ; Hofbauer, L.C. ; Kleuser, B. ; Chun, J. ; Schinke, T. ; Amling, M.
Calcitonin controls bone formation by inhibiting the release of sphingosine 1-phosphate from osteoclasts.Aichler, M. ; Luber, B. ; Lordick, F. ; Walch, A.K.
Proteomic and metabolic prediction of response to therapy in gastric cancer.Huber, K. ; Feuchtinger, A. ; Borgmann, D.M. ; Li, Z. ; Aichler, M. ; Hauck, S.M. ; Zitzelsberger, H. ; Schwaiger, M. ; Keller, U. ; Walch, A.K.
A novel approach of MALDI drug imaging, immunohistochemistry, and digital image analysis for drug distribution studies in tissues.Gegg, M. ; Böttcher, A. ; Burtscher, I. ; Hasenöder, S. ; van Campenhout, C.A. ; Aichler, M. ; Walch, A.K. ; Grant, S.G. ; Lickert, H.
Flattop regulates basal body docking and positioning in mono- and multiciliated cells.Balluff, B. ; Frese, C.K. ; Maier, S.K. ; Schöne, C. ; Kuster, B. ; Schmitt, M. ; Aubele, M. ; Höfler, H. ; Deelder, A.M. ; Heck, A.J. ; Hogendoorn, P.C.W. ; Morreau, J. ; Altelaar, A.F. ; Walch, A.K. ; McDonnell, L.A.
De novo discovery of phenotypic intra-tumor heterogeneity using imaging mass spectrometry.Aichler, M. ; Motschmann, M. ; Jütting, U. ; Luber, B. ; Becker, K. ; Ott, K. ; Lordick, F. ; Langer, R. ; Feith, M. ; Siewert, J.R. ; Walch, A.K.
Epidermal Growth Factor Receptor (EGFR) is an independent adverse prognostic factor in esophageal adenocarcinoma patients treated with cisplatin-based neoadjuvant chemotherapy.Feuchtinger, A. ; Stiehler, T. ; Jütting, U. ; Marjanovic, G. ; Luber, B. ; Langer, R. ; Walch, A.K.
Image analysis of immunohistochemistry is superior to visual scoring as shown for patient outcome of esophageal adenocarcinoma.Maier, S.K. ; Bashkueva, K. ; Rösli, C. ; Skerra, A. ; Kuster, B.
PAS-cal: A repetitive peptide sequence calibration standard for MALDI mass spectrometry.Weber, E. ; Finsterbusch, K. ; Lindquist, R. ; Nair, S. ; Lienenklaus, S. ; Gekara, N.O. ; Janik, D. ; Weiss, S. ; Kalinke, U. ; Overby, A.K. ; Kröger, A.
Type I interferon protects mice from fatal neurotropic infection with Langat virus by systemic and local anti-viral response.Kraus, P. ; Sivakamasundari, V. ; Yu, H.B. ; Xing, X. ; Lim, S.L. ; Adler, T. ; Aguilar-Pimentel, J.A. ; Becker, L. ; Bohla, A. ; Garrett, L. ; Hans, W. ; Hölter, S.M. ; Janas, E. ; Moreth, K. ; Prehn, C. ; Puk, O. ; Rathkolb, B. ; Rozman, J. ; Adamski, J. ; Bekeredjian, R. ; Busch, D.H. ; Graw, J. ; Klingenspor, M. ; Klopstock, T. ; Neff, F. ; Ollert, M. ; Stöger, T. ; Yildirim, A.Ö. ; Eickelberg, O. ; Wolf, E. ; Wurst, W. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Lufkin, T. ; Stanton, L.W.
Pleiotropic functions for transcription factor Zscan10.Rosemann, M. ; Gonzalez-Vasconcellos, I. ; Domke, T. ; Kuosaite, V. ; Schneider, R. ; Kremer, M. ; Favor, J. ; Nathrath, M. ; Atkinson, M.J.
A Rb1 promoter variant with reduced activity contributes to osteosarcoma susceptibility in irradiated mice.Ehninger, D. ; Neff, F. ; Xie, K.
Longevity, aging and rapamycin.Slotta-Huspenina, J. ; Becker, K.F. ; Feith, M. ; Walch, A.K. ; Langer, R.
Heat Shock Protein 90 (HSP90) and Her2 in adenocarcinomas of the esophagus.Schmitt, S. ; Schulz, S. ; Schropp, E.-M. ; Eberhagen, C. ; Simmons, A. ; Beisker, W. ; Aichler, M. ; Zischka, H.
Why to compare absolute numbers of mitochondria.Arabi, L. ; Gsponer, J.R. ; Smida, J. ; Nathrath, M. ; Perrina, V. ; Jundt, G. ; Ruiz, C. ; Quagliata, L. ; Baumhoer, D.
Upregulation of the miR-17-92 cluster and its two paraloga in osteosarcoma - reasons and consequences.Buck, A. ; Walch, A.K.
In situ drug and metabolite analyzes in biological and clinical research by MALDI MS imaging.Heimesaat, M.M. ; Fischer, A. ; Plickert, R. ; Wiedemann, T. ; Loddenkemper, C. ; Göbel, U.B. ; Bereswill, S. ; Rieder, G.
Helicobacter pylori induced gastric immunopathology is associated with distinct microbiota changes in the large intestines of long-term infected Mongolian gerbils.Graf, N. ; Li, Z. ; Herrmann, K. ; Weh, D. ; Aichler, M. ; Slawska, J. ; Walch, A.K. ; Peschel, C. ; Schwaiger, M. ; Buck, A.K. ; Dechow, T. ; Keller, U.
Positron emission tomographic monitoring of dual phosphatidylinositol-3-kinase and mTOR inhibition in anaplastic large cell lymphoma.Longuini, V.C. ; Lourenco-Jr, D.M. ; Sekiya, T. ; Meirelles, O.D. ; Goncalves, T.D. ; Coutinho, F.L. ; Francisco, G. ; Osaki, L.H. ; Chammas, R. ; Alves, V.A. ; Siqueira, S.A. ; Schlesinger, D. ; Naslavsky, M.S. ; Zatz, M. ; Duarte, Y.A. ; Lebrao, M.L. ; Gama, P. ; Lee, M.S. ; Molatore, S. ; Pereira, M.A. ; Jallad, R.S. ; Bronstein, M.D. ; Cunha Neto, M.B. ; Liberman, B. ; Fragoso, M.C. ; Toledo, S.P. ; Pellegata, N.S. ; Toledo, R.A.
Association between the p27 rs2066827 variant and tumor multiplicity in patients harboring MEN1 germline mutations.Zumbrennen-Bullough, K.B. ; Becker, L. ; Garrett, L. ; Hölter, S.M. ; Calzada-Wack, J. ; Mossbrugger, I. ; Quintanilla-Fend, L. ; Rácz, I. ; Rathkolb, B. ; Klopstock, T. ; Wurst, W. ; Zimmer, A. ; Wolf, E. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Romney, S.J. ; Leibold, E.A.
Abnormal brain iron metabolism in Irp2 deficient mice is associated with mild neurological and behavioral impairments.Poos, K. ; Smida, J. ; Nathrath, M. ; Maugg, D. ; Baumhoer, D. ; Neumann, A. ; Korsching, E.
Structuring osteosarcoma knowledge: An osteosarcoma-gene association database based on literature mining and manual annotation.Gorzolka, K. ; Walch, A.K.
MALDI mass spectrometry imaging of formalin-fixed paraffin-embedded tissues in clinical research.Huber, K. ; Aichler, M. ; Sun, N. ; Buck, A. ; Li, Z. ; Fernandez, I.E. ; Hauck, S.M. ; Zitzelsberger, H. ; Eickelberg, O. ; Janssen, K.P. ; Keller, U. ; Walch, A.K.
A rapid ex vivo tissue model for optimising drug detection and ionisation in MALDI imaging studies.Meier, R. ; Braren, R. ; Kosanke, Y. ; Bussemer, J. ; Neff, F. ; Wildgruber, M. ; Schwarzenböck, S. ; Frank, A. ; Haller, B. ; Hohlbaum, A.M. ; Schwaiger, M. ; Gille, H. ; Rummeny, E.J. ; Beer, A.J.
Multimodality multiparametric imaging of early tumor response to a novel antiangiogenic therapy based on anticalins.Dekker, T.J. ; Balluff, B.D. ; Jones, E.A. ; Schöne, C.D. ; Schmitt, M. ; Aubele, M. ; Kroep, J.R. ; Smit, V.T. ; Tollenaar, R.A. ; Mesker, W.E. ; Walch, A.K. ; McDonnell, L.A.
Multicenter Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging (MALDI MSI) identifies proteomic differences in breast-cancer-associated stroma.Jin, S. ; Kim, J. ; Willert, T. ; Klein-Rodewald, T. ; Garcia-Dominguez, M. ; Mosqueira, M. ; Fink, R. ; Esposito, I. ; Hofbauer, L.C. ; Charnay, P. ; Kieslinger, M.
Ebf factors and MyoD cooperate to regulate muscle relaxation via Atp2a1.Ewald, F. ; Annemann, M. ; Pils, M.C. ; Plaza-Sirvent, C. ; Neff, F. ; Erck, C. ; Reinhold, D. ; Schmitz, I.
Constitutive expression of murine c-FLIPR causes autoimmunity in aged mice.Bézière, N. ; von Schacky, C. ; Kosanke, Y. ; Kimm, M. ; Nunes, A. ; Licha, K. ; Aichler, M. ; Walch, A.K. ; Rummeny, E.J. ; Ntziachristos, V. ; Meier, R.
Optoacoustic imaging and staging of arthritic inflammation.Malinowsky, K. ; Nitsche, U. ; Janssen, K.P. ; Bader, F.G. ; Späth, C. ; Drecoll, E. ; Keller, G. ; Höfler, H. ; Slotta-Huspenina, J. ; Becker, K.F.
Activation of the PI3K/AKT pathway correlates with prognosis in stage II colon cancer.Sekiya, T. ; Bronstein, M.D. ; Benfini, K. ; Longuini, V.C. ; Jallad, R.S. ; Machado, M.C. ; Goncalves, T.D. ; Osaki, L.H. ; Higashi, L. ; Lima-Jr, J.V. ; Kater, C.E. ; Lee, M. ; Molatore, S. ; Francisco, G. ; Chammas, R. ; Naslavsky, M. ; Schlesinger, D. ; Gama, P. ; Duarte, Y.A. ; Lebrao, M.L. ; Zatz, M. ; Meirelles, O. ; Liberman, B. ; Fragoso, M.C. ; Toledo, S.P. ; Pellegata, N.S. ; Toledo, R.A.
p27 variant and corticotropinoma susceptibility: A genetic and in vitro study.Kucharska, J. ; del Río, P. ; Arango-González, B. ; Gorza, M. ; Feuchtinger, A. ; Hauck, S.M. ; Ueffing, M.
Cyr61 activates retinal cells and prolongs photoreceptor survival in rd1 mouse model of retinitis pigmentosa.Niedzielska, M. ; Bodendorfer, B. ; Münch, S. ; Eichner, A. ; Derigs, M. ; da Costa, O.P. ; Schweizer, A. ; Neff, F. ; Nitschke, L. ; Sparwasser, T. ; Keyse, S.M. ; Lang, R.
Gene trap mice reveal an essential function of dual specificity phosphatase Dusp16/MKP-7 in perinatal survival and regulation of Toll-Like Receptor (TLR)-induced cytokine production.Stribl, C.B. ; Samara, A. ; Trümbach, D. ; Augustin, R. ; Neumann, M. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Rathkolb, B. ; Wolf, E. ; Beckers, J. ; Horsch, M. ; Neff, F. ; Kremmer, E. ; Koob, S. ; Reichert, A.S. ; Hans, W. ; Rozman, J. ; Klingenspor, M. ; Aichler, M. ; Walch, A.K. ; Becker, L. ; Klopstock, T. ; Glasl, L. ; Hölter, S.M. ; Wurst, W. ; Floß, T.
Mitochondrial dysfunction and decrease in body weight of a transgenic knock-in mouse model for TDP-43.Avitzur, Y. ; Guo, C. ; Mastropaolo, L.A. ; Bahrami, E. ; Chen, H. ; Zhao, Z. ; Elkadri, A. ; Dhillon, S. ; Murchie, R. ; Fattouh, R. ; Huynh, H. ; Walker, J.L. ; Wales, P.W. ; Cutz, E. ; Kakuta, Y. ; Dudley, J. ; Kammermeier, J. ; Powrie, F. ; Shah, N. ; Walz, C. ; Nathrath, M. ; Kotlarz, D. ; Puchaka, J. ; Krieger, J. ; Racek, T. ; Kirchner, T. ; Walters, T.D. ; Brumell, J.H. ; Griffiths, A.M. ; Rezaei, N. ; Rashtian, P. ; Najafi, M. ; Monajemzadeh, M. ; Pelsue, S. ; McGovern, D.P. ; Uhlig, H.H. ; Schadt, E. ; Klein, C. ; Snapper, S.B. ; Muise, A.M.
Mutations in tetratricopeptide repeat domain 7A result in a severe form of very early onset inflammatory bowel disease.Sun, N. ; Ly, A. ; Meding, S. ; Witting, M. ; Hauck, S.M. ; Ueffing, M. ; Schmitt-Kopplin, P. ; Aichler, M. ; Walch, A.K.
High-resolution metabolite imaging of light and dark treated retina using MALDI-FTICR mass spectrometry.Li, Z. ; Herrmann, K. ; Pirsig, S. ; Philipp-Abbrederis, K. ; Henninger, M. ; Aichler, M. ; Feuchtinger, A. ; Walch, A.K. ; Beer, A.J. ; Ringshausen, I. ; Pomykala, K.L. ; Scheidhauer, K. ; Schwaiger, M. ; Keller, U. ; Buck, A.K.
Molecular imaging for early prediction of response to Sorafenib treatment in sarcoma.Wildgruber, M. ; Bielicki, I. ; Aichler, M. ; Kosanke, K. ; Feuchtinger, A. ; Settles, M. ; Onthank, D.C. ; Cesati, R.R. ; Robinson, S.P. ; Huber, A.M. ; Rummeny, E.J. ; Walch, A.K. ; Botnar, R.M.
Assessment of myocardial infarction and post-infarction scar remodeling with an elastin-specific magnetic resonance agent.McDonnell, L.A. ; Walch, A.K. ; Stoeckli, M. ; Corthals, G.L.
MSiMass list: A public database of identifications for protein MALDI MSI.Baumhoer, D. ; Brunner, P. ; Eppenberger-Castori, S. ; Smida, J. ; Nathrath, M. ; Jundt, G.
Osteosarcomas of the jaws differ from their peripheral counterparts and require a distinct treatment approach. Experiences from the DOESAK registry.Aichler, M. ; Walch, A.K.
In brief: The (molecular) pathogenesis of Barrett's oesophagus.Mengel, D. ; Röskam, S. ; Neff, F. ; Balakrishnan, K. ; Deuster, O. ; Gold, M. ; Oertel, W.H. ; Bacher, M. ; Bach, J.P. ; Dodel, R.
Naturally occurring autoantibodies interfere with β-amyloid metabolism and improve cognition in a transgenic mouse model of Alzheimer's disease 24 h after single treatment.Aichler, M.
Bildgebende MS in biomedizinischer Forschung und Diagnostik.Sluka, S.H.M. ; Akhmedov, A. ; Klein-Rodewald, T. ; Horsch, M. ; Rathkolb, B. ; Neff, F. ; Hrabě de Angelis, M. ; Ruf, W. ; Luescher, T.F. ; Tanner, F.C.
Single housing reduces lung hemorrhages in male mice with tissue factor disulfide mutation and protects them from lethality.Frankó, A. ; Baris, O.R. ; Bergschneider, E. ; von Toerne, C. ; Hauck, S.M. ; Aichler, M. ; Walch, A.K. ; Wurst, W. ; Wiesner, R.J. ; Johnston, I.C.D. ; Hrabě de Angelis, M.
Efficient isolation of pure and functional mitochondria from mouse tissues using automated tissue disruption and enrichment with anti-TOM22 magnetic beads.Serpi, R. ; Klein-Rodewald, T. ; Calzada-Wack, J. ; Neff, F. ; Schuster, T. ; Gailus-Durner, V. ; Fuchs, H. ; Poutanen, M. ; Hrabě de Angelis, M. ; Esposito, I.
Inbred wild type mouse strains have distinct spontaneous morphological phenotypes.Ale, A.B.F ; Siebenhaar, F. ; Kosanke, K. ; Aichler, M. ; Radrich, K. ; Heydrich, S. ; Schiemann, M. ; Bielicki, I. ; Noel, P.B. ; Braren, R. ; Maurer, M. ; Walch, A.K. ; Rummeny, E.J. ; Ntziachristos, V. ; Wildgruber, M.
Cardioprotective C-kit+ bone marrow cells attenuate apoptosis after acute myocardial infarction in mice – in-vivo assessment with fluorescence molecular imaging.Mittermeyer, G. ; Malinowsky, K. ; Beese, C. ; Höfler, H. ; Schmalfeldt, B. ; Becker, K.F. ; Avril, S.
Variation in cell signaling protein expression may introduce sampling bias in primary epithelial ovarian cancer.Gaertner, F.C. ; Wiedemann, T. ; Yousefi, B.H. ; Lee, M.S. ; Repokis, I. ; Higuchi, T. ; Nekolla, S.G. ; Yu, M. ; Robinson, S. ; Schwaiger, M. ; Pellegata, N.S.
Preclinical evaluation of 18F-LMI1195 for in vivo imaging of pheochromocytoma in the MENX tumor model.Lee, M. ; Pellegata, N.S.
Multiple endocrine neoplasia syndromes associated with mutation of p27.Falkenberg, N. ; Anastasov, N. ; Rappl, K. ; Braselmann, H. ; Auer, G. ; Walch, A.K. ; Huber, M. ; Höfig, I. ; Schmitt, M. ; Höfler, H. ; Atkinson, M.J. ; Aubele, M.
MiR-221/-222 differentiate prognostic groups in advanced breast cancers and influence cell invasion.Gross, E. ; Meul, C. ; Raab, S. ; Propping, C. ; Avril, S. ; Aubele, M. ; Gkazepis, A. ; Schuster, T. ; Grebenchtchikov, N. ; Schmitt, M. ; Kiechle, M. ; Meijer, J. ; Vijzelaar, R. ; Meindl, A. ; van Kuilenburg, A.B.
Somatic copy number changes in DPYD are associated with lower risk of recurrence in triple-negative breast cancers.Altomonte, J. ; Marozin, S. ; de Toni, E.N. ; Rizzani, A. ; Esposito, I. ; Steiger, K. ; Feuchtinger, A. ; Hellerbrand, C. ; Schmid, R.M. ; Ebert, O.
Antifibrotic properties of transarterial oncolytic VSV therapy for hepatocellular carcinoma in rats with thioacetamide-induced liver fibrosis.Grunewald, T.G. ; Willier, S. ; Janik, D. ; Unland, R. ; Reiss, C. ; da Costa, O.P. ; Buch, T. ; Dirksen, U. ; Richter, G.H. ; Neff, F. ; Burdach, S. ; Butt, E.
The zyxin-related protein Thyroid Receptor Interacting Protein 6 (TRIP6) is overexpressed in Ewing's sarcoma and promotes migration, invasion and cell growth.Poos, K. ; Smida, J. ; Nathrath, M. ; Maugg, D. ; Baumhoer, D. ; Korsching, E.
How microRNA and transcription factor co-regulatory networks affect osteosarcoma cell proliferation.Hahne, H. ; Pachl, F. ; Ruprecht, B. ; Maier, S.K. ; Klaeger, S. ; Helm, D. ; Médard, G. ; Wilm, M. ; Lemeer, S. ; Kuster, B.
DMSO enhances electrospray response, boosting sensitivity of proteomic experiments.Schmitt, S. ; Saathoff, F. ; Meissner, L. ; Schropp, E.-M. ; Lichtmannegger, J. ; Schulz, S. ; Eberhagen, C. ; Borchard, S. ; Aichler, M. ; Adamski, J. ; Plesnila, N. ; Rothenfusser, S. ; Kroemer, G. ; Zischka, H.
A semi-automated method for isolating functionally intact mitochondria from cultured cells and tissue biopsies.Pallua, J.D. ; Schaefer, G. ; Seifarth, C. ; Becker, M. ; Meding, S. ; Rauser, S. ; Walch, A.K. ; Handler, M. ; Netzer, M. ; Popovscaia, M. ; Osl, M. ; Baumgartner, C. ; Lindner, H. ; Kremser, L. ; Sarg, B. ; Bartsch, G. ; Huck, C.W. ; Bonn, G.K. ; Klocker, H.
MALDI-MS tissue imaging identification of biliverdin reductase B overexpression in prostate cancer.Simon, M.M. ; Greenaway, S. ; White, J.K. ; Fuchs, H. ; Gailus-Durner, V. ; Sorg, T. ; Wong, K. ; Bedu, E. ; Cartwright, E.J. ; Dacquin, R. ; Estabel, J. ; Graw, J. ; Ingham, N.J. ; Jackson, I.J. ; Lengeling, A. ; Mandillo, S. ; Marvel, J. ; Meziane, H. ; Preitner, F. ; Puk, O. ; Roux, M. ; Adams, D.J. ; Atkins, S. ; Ayadi, A. ; Becker, L. ; Blake, A. ; Brooker, D. ; Cater, H. ; Champy, M.-F. ; Combe, R. ; Danecek, P. ; di Fenza, A. ; Gates, H. ; Gerdin, A.-K. ; Golini, E. ; Hancock, J.M. ; Hans, W. ; Hölter, S.M. ; Hough, T. ; Jurdic, P. ; Keane, T.M ; Morgan, H. ; Müller, W. ; Neff, F. ; Nicholson, G. ; Pasche, B. ; Roberson, L.-A. ; Rozman, J. ; Sanderson, M. ; Santos, L. ; Selloum, M. ; Shannon, C. ; Southwell, A. ; Tocchini-Valentini, G.P. ; Vancollie, V.E. ; Wells, S. ; Westerberg, H. ; Wurst, W. ; Zi, M. ; Yalcin, B. ; Ramirez-Solis, R. ; Steel, K.P. ; Mallon, A.-M. ; Hrabě de Angelis, M. ; Herault, Y. ; Brown, S.D.M.
A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains.Balluff, B.
MALDI imaging mass spectrometry in clinical proteomics research of gastric cancer tissues.Neubert, P. ; Walch, A.K.
Current frontiers in clinical research application of MALDI imaging mass spectrometry.Slotta-Huspenina, J. ; Wolff, C. ; Drecoll, E. ; Feith, M. ; Bettstetter, M. ; Malinowsky, K. ; Bauer, L. ; Becker, K. ; Ott, K. ; Höfler, H. ; Becker, K.F. ; Langer, R.
A specific expression profile of heat-shock proteins and glucose-regulated proteins is associated with response to neoadjuvant chemotherapy in oesophageal adenocarcinomas.Berezowska, S. ; Novotny, A. ; Bauer, K. ; Feuchtinger, A. ; Slotta-Huspenina, J. ; Becker, K. ; Langer, R. ; Walch, A.K.
Association between HSP90 and Her2 in gastric and gastroesophageal carcinomas.Sun, N. ; Walch, A.K.
Qualitative and quantitative mass spectrometry imaging of drugs and metabolites in tissue at therapeutic levels.Neff, F. ; Flores-Dominguez, D. ; Ryan, D.P. ; Horsch, M. ; Schröder, S. ; Adler, T. ; Afonso, L.C. ; Aguilar-Pimentel, J.A. ; Becker, L. ; Garrett, L. ; Hans, W. ; Hettich, M.M. ; Holtmeier, R. ; Hölter, S.M. ; Moreth, K. ; Prehn, C. ; Puk, O. ; Rácz, I. ; Rathkolb, B. ; Rozman, J. ; Naton, B. ; Ordemann, R. ; Adamski, J. ; Beckers, J. ; Bekeredjian, R. ; Busch, D.H. ; Ehninger, G. ; Graw, J. ; Höfler, H. ; Klingenspor, M. ; Klopstock, T. ; Ollert, M. ; Stypmann, J. ; Wolf, E. ; Wurst, W. ; Zimmer, A. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Ehniger, D.
Rapamycin extends murine lifespan but has limited effects on aging.Sabrautzki, S. ; Janas, E. ; Lorenz-Depiereux, B. ; Calzada-Wack, J. ; Aguilar-Pimentel, J.A. ; Rathkolb, B. ; Adler, T. ; Cohrs, C.M. ; Hans, W. ; Diener, S. ; Fuchs, H. ; Gailus-Durner, V. ; Busch, D.H. ; Höfler, H. ; Ollert, M. ; Strom, T.M. ; Wolf, E. ; Neff, F. ; Hrabě de Angelis, M.
An ENU mutagenesis-derived mouse model with a dominant Jak1 mutation resembling phenotypes of systemic autoimmune disease.Hilber, B.H.J.
Klinisch-pathologische Bedeutung des Signalweges des Rezeptors des epidermalen Wachstumsfaktors (EGFR) beim Adenokarzinom des gastroösophagealen Übergangs Typ I (Barrett-Karzinom).Maier, S.K. ; Hahne, H. ; Moghaddas Gholami, A. ; Balluff, B. ; Meding, S. ; Schoene, C. ; Walch, A.K. ; Kuster, B.
Comprehensive identification of proteins from MALDI imaging.Wortmann, M. ; Schneider, M. ; Pircher, J. ; Hellfritsch, J. ; Aichler, M. ; Vegi, N. ; Koelle, P. ; Kuhlencordt, P. ; Walch, A.K. ; Pohl, U. ; Bornkamm, G.W. ; Conrad, M. ; Beck, H.
Combined deficiency in glutathione peroxidase 4 and vitamin E causes multi-organ thrombus formation and early death in mice.Bonzheim, I. ; Irmler, M. ; Klier-Richter, M. ; Steinhilber, J. ; Anastasov, N. ; Schafer, S. ; Adam, P. ; Beckers, J. ; Raffeld, M. ; Fend, F. ; Quintanilla-Martinez, L.
Identification of C/EBPβ target genes in ALK+ Anaplastic Large Cell Lymphoma (ALCL) by gene expression profiling and chromatin immunoprecipitation.Lee, M.S. ; Marinoni, I. ; Irmler, M. ; Psaras, T. ; Honegger, J.B. ; Beschorner, R. ; Anastasov, N. ; Beckers, J. ; Theodoropoulou, M. ; Roncaroli, F. ; Pellegata, N.S.
Transcriptome analysis of MENX-associated rat pituitary adenomas identifies novel molecular mechanisms involved in the pathogenesis of human pituitary gonadotroph adenomas.Schulz, S. ; Schmitt, S. ; Wimmer, R. ; Aichler, M. ; Eisenhofer, S. ; Lichtmannegger, J. ; Eberhagen, C. ; Artmann, R. ; Toókos, F. ; Walch, A.K. ; Krappmann, D. ; Brenner-Jan, C. ; Rust, C. ; Zischka, H.
Progressive stages of mitochondrial destruction caused by cell toxic bile salts.Richter, G.H.S. ; Fasan, A. ; Hauer, K. ; Grunewald, T.G.P. ; Berns, C. ; Rössler, S. ; Naumann, I. ; Staege, M.S. ; Fulda, S. ; Esposito, I. ; Burdach, S.
G-protein coupled receptor 64 promotes invasiveness and metastasis in Ewing sarcomas through PGF and MMP1.Taruttis, A. ; Wildgruber, M. ; Kosanke, K. ; Bézière, N. ; Licha, K. ; Haag, R. ; Aichler, M. ; Walch, A.K. ; Rummeny, E. ; Ntziachristos, V.
Multispectral optoacoustic tomography of myocardial infarction.Krebs, K.M. ; Böttinger, N. ; Huang, L.R. ; Chmielewski, M. ; Arzberger, S. ; Gasteiger, G. ; Jager, C. ; Schmitt, E. ; Bohne, F. ; Aichler, M. ; Uckert, W. ; Abken, H. ; Heikenwälder, M. ; Knolle, P. ; Protzer, U.
T cells expressing a chimeric antigen receptor that binds hepatitis B virus envelope proteins control virus replication in mice.Ludyga, N. ; Englert, S. ; Pflieger, K. ; Rauser, S. ; Braselmann, H. ; Walch, A.K. ; Auer, G. ; Höfler, H. ; Aubele, M.
The impact of Cysteine-Rich Intestinal Protein 1 (CRIP1) in human breast cancer.Azimzadeh, O. ; Sievert, W. ; Sarioglu, H. ; Yentrapalli, R. ; Barjaktarovic, Z. ; Sriharshan, A. ; Ueffing, M. ; Janik, D. ; Aichler, M. ; Atkinson, M.J. ; Multhoff, G. ; Tapio, S.
PPAR alpha: A novel radiation target in locally exposed Mus musculus heart revealed by quantitative proteomics.Tapfer, A. ; Braren, R. ; Bech, M. ; Willner, M. ; Zanette, I. ; Weitkamp, T. ; Trajkovic-Arsic, M. ; Siveke, J.T. ; Settles, M. ; Aichler, M. ; Walch, A.K. ; Pfeiffer, F.
X-ray phase-contrast CT of a pancreatic ductal adenocarcinoma mouse model.Aichler, M. ; Elsner, M. ; Ludyga, N. ; Feuchtinger, A. ; Zangen, V. ; Maier, S.K. ; Balluff, B. ; Schöne, C. ; Hierber, L. ; Braselmann, H. ; Meding, S. ; Rauser, S. ; Zischka, H. ; Aubele, M. ; Schmitt, M. ; Feith, M. ; Hauck, S.M. ; Ueffing, M. ; Langer, R. ; Kuester, B. ; Zitzelsberger, H. ; Höfler, H. ; Walch, A.K.
Clinical response to chemotherapy in oesophageal adenocarcinoma patients is linked to defects in mitochondria.Vogel, K.U. ; Edelmann, S.L. ; Jeltsch, K. ; Bertossi, A. ; Heger, K. ; Heinz, G.A. ; Zöller, J. ; Warth, S.C. ; Hoefig, K.P. ; Lohs, C. ; Neff, F. ; Kremmer, E. ; Schick, J. ; Repsilber, D. ; Geerlof, A. ; Blum, H. ; Wurst, W. ; Heikenwälder, M. ; Schmidt-Supprian, M. ; Heissmeyer, V.
Roquin paralogs 1 and 2 redundantly repress the Icos and Ox40 costimulator mRNAs and control follicular helper T cell differentiation.Oetjen, J. ; Aichler, M. ; Trede, D. ; Strehlow, J. ; Berger, J. ; Heldmann, S. ; Becker, M. ; Gottschalk, M. ; Kobarg, J.H. ; Wirtz, S. ; Schiffler, S. ; Thiele, H. ; Walch, A.K. ; Maass, P. ; Alexandrov, T.
MRI-compatible pipeline for three-dimensional MALDI imaging mass spectrometry using PAXgene fixation.Occhi, G. ; Regazzo, D. ; Trivellin, G. ; Boaretto, F. ; Ciato, D. ; Bobisse, S. ; Ferasin, S. ; Cetani, F. ; Pardi, E. ; Korbonits, M. ; Pellegata, N.S. ; Sidarovich, V. ; Quattrone, A. ; Opocher, G. ; Mantero, F. ; Scaroni, C.
A novel mutation in the upstream open reading frame of the CDKN1B gene causes a MEN4 phenotype.Lee, M.S. ; Pellegata, N.S.
Folate receptor-mediated drug targeting: A possible strategy for nonfunctioning pituitary adenomas?Ludyga, N. ; Anastasov, N. ; Rosemann, M. ; Seiler, J. ; Lohmann, N. ; Braselmann, H. ; Mengele, K. ; Schmitt, M. ; Höfler, H. ; Aubele, M.
Effects of simultaneous knockdown of HER2 and PTK6 on malignancy and tumor progression in human breast cancer cells.Schöne, C. ; Höfler, H. ; Walch, A.K.
MALDI imaging mass spectrometry in cancer research: Combining proteomic profiling and histological evaluation.Meding, S. ; Walch, A.K.
MALDI imaging mass spectrometry for direct tissue analysis.Müller, T.D. ; Lee, S.J. ; Jastroch, M. ; Kabra, D. ; Stemmer, K. ; Aichler, M. ; Abplanalp, B. ; Ananthakrishnan, G. ; Bhardwaj, N. ; Collins, S. ; Divanovic, S. ; Endele, M. ; Finan, B. ; Gao, Y. ; Habegger, K.M. ; Hembree, J. ; Heppner, K.M. ; Hofmann, S. ; Holland, J. ; Küchler, D. ; Kutschke, M. ; Krishna, R. ; Lehti, M. ; Oelkrug, R. ; Ottaway, N. ; Perez-Tilve, D. ; Raver, C. ; Walch, A.K. ; Schriever, S.C. ; Speakman, J. ; Tseng, Y.H. ; Diaz-Meco, M. ; Pfluger, P.T. ; Moscat, J. ; Tschöp, M.H.
P62 links β-adrenergic input to mitochondrial function and thermogenesis.Marinoni, I. ; Lee, M.S. ; Mountford, S. ; Perren, A. ; Bravi, I. ; Jennen, L. ; Feuchtinger, A. ; Drouin, J. ; Roncaroli, F. ; Pellegata, N.S.
Characterization of MENX-associated pituitary tumours.Bettstetter, M. ; Berezowska, S. ; Keller, G. ; Walch, A.K. ; Feuchtinger, A. ; Slotta-Huspenina, J. ; Feith, M. ; Drecoll, E. ; Höfler, H. ; Langer, R.
Epidermal growth factor receptor, phosphatidylinositol-3-kinase catalytic subunit/PTEN, and KRAS/NRAS/BRAF in primary resected esophageal adenocarcinomas: Loss of PTEN is associated with worse clinical outcome.Hauer, K. ; Calzada-Wack, J. ; Steiger, K. ; Grunewald, T.G. ; Baumhoer, D. ; Plehm, S. ; Buch, T. ; Prazeres da Costa, O. ; Esposito, I. ; Burdach, S. ; Richter, G.H.
DKK2 mediates osteolysis, invasiveness and metastatic spread in Ewing sarcoma.Domke, T.A.J.
Histologische und molekularbiologische Untersuchung Thorium-222-induzierter Osteosarkome bei Rb1 konditionellen und p16 konstitutiven knockout-Mäusen.Grüner, B.M.
Molecular and proteomic analysis of signaling pathways in pancreatic ductal adenocarcinoma using genetically engineered mouse models.Hahne, H. ; Neubert, P. ; Kuhn, K. ; Etienne, C. ; Bomgarden, R. ; Rogers, J.C. ; Kuster, B.
Carbonyl-reactive tandem mass tags for the proteome-wide quantification of N-linked glycans.Janik, D. ; Mossbrugger, I. ; Calzada-Wack, J. ; Quintanella-Martinez, L. ; Gailus-Durner, V. ; Fuchs, H. ; Hrabě de Angelis, M. ; Neff, F.
Spontane ZNS-Veränderungen in den Screens der German Mouse Clinic.Anastasov, N. ; Höfig, I. ; Vasconcellos, I.G. ; Rappl, K. ; Braselmann, H. ; Ludyga, N. ; Auer, G. ; Aubele, M. ; Atkinson, M.J.
Radiation resistance due to high expression of miR-21 and G2/M checkpoint arrest in breast cancer cells.Becker, K. ; Reim, D. ; Novotny, A. ; zum Büschenfelde, C.M. ; Engel, J. ; Friess, H. ; Höfler, H. ; Langer, R.
Proposal for a multifactorial prognostic score that accurately classifies 3 groups of gastric carcinoma patients with different outcomes after neoadjuvant chemotherapy and surgery.Schäfer, A. ; Teufel, J. ; Ringel, F. ; Bettstetter, M. ; Hoepner, I. ; Rasper, M. ; Gempt, J. ; Koeritzer, J. ; Schmidt-Graf, F. ; Meyer, B. ; Beier, C.P. ; Schlegel, J.
Aldehyde dehydrogenase 1A1 - a new mediator of resistance to temozolomide in glioblastoma.Feuerecker, B. ; Pirsig, S. ; Seidl, C. ; Aichler, M. ; Feuchtinger, A. ; Bruchelt, G. ; Senekowitsch-Schmidtke, R.
Lipoic acid inhibits cell proliferation of tumor cells in vitro and in vivo.Malinowsky, K. ; Wolff, C. ; Berg, D. ; Schuster, T. ; Walch, A.K. ; Bronger, H. ; Mannsperger, H. ; Schmidt, C. ; Korf, U. ; Höfler, H. ; Becker, K.F.
uPA and PAI-1-related signaling pathways differ between primary breast cancers and lymph node metastases.Meding, S. ; Balluff, B. ; Elsner, M. ; Schöne, C. ; Rauser, S. ; Nitsche, U. ; Maak, M. ; Schäfer, A. ; Hauck, S.M. ; Ueffing, M. ; Langer, R. ; Höfler, H. ; Friess, H. ; Rosenberg, R. ; Walch, A.K.
Tissue-based proteomics reveals FXYD3, S100A11 and GSTM3 as novel markers for regional lymph node metastasis in colon cancer.Wulfkuhle, J.D. ; Berg, D. ; Wolff, C. ; Langer, R. ; Tran, K. ; Illi, J. ; Espina, V. ; Pierobon, M. ; Deng, J. ; Demichele, A. ; Walch, A.K. ; Bronger, H. ; Becker, I. ; Waldhör, C. ; Höfler, H. ; Esserman, L. ; Liotta, L.A. ; Becker, K.F. ; Petricoin, E.F.
Molecular analysis of HER2 signaling in human breast cancer by functional protein pathway activation mapping.Graf, N. ; Herrmann, K. ; Numberger, B. ; Zwisler, D. ; Aichler, M. ; Feuchtinger, A. ; Schuster, T. ; Wester, H.-J. ; Senekowitsch-Schmidtke, R. ; Peschel, C. ; Schwaiger, M. ; Keller, U. ; Dechow, T. ; Buck, A.K.
[18F]FLT is superior to [18F]FDG for predicting early response to antiproliferative treatment in high-grade lymphoma in a dose-dependent manner.Fuchs, H. ; Gailus-Durner, V. ; Neschen, S. ; Adler, T. ; Afonso, L.C. ; Aguilar-Pimentel, J.A. ; Becker, L. ; Bohla, A. ; Calzada-Wack, J. ; Cohrs, C.M. ; Dewert, A. ; Fridrich, B. ; Garrett, L. ; Glasl, L. ; Götz, A. ; Hans, W. ; Hölter, S.M. ; Horsch, M. ; Hurt, A. ; Janas, E. ; Janik, D. ; Kahle-Stephan, M. ; Kistler, M. ; Klein-Rodewald, T. ; Lengger, C. ; Ludwig, T. ; Maier, H. ; Marschall, S. ; Micklich, K. ; Möller, G. ; Naton, B. ; Prehn, C. ; Puk, O. ; Rácz, I. ; Räß, M. ; Rathkolb, B. ; Rozman, J. ; Scheerer, M. ; Schiller, E. ; Schrewe, A. ; Steinkamp, R. ; Stoeger, C. ; Sun, M. ; Szymczak, W. ; Treise, I. ; Vargas Panesso, I.L. ; Vernaleken, A. ; Willershäuser, M. ; Zimprich, A. ; Zeh, R.M. ; Adamski, J. ; Beckers, J. ; Bekeredjian, R. ; Busch, D.H. ; Eickelberg, O. ; Favor, J. ; Graw, J. ; Höfler, H. ; Hoeschen, C. ; Katus, H.A. ; Klingenspor, M. ; Klopstock, T. ; Neff, F. ; Ollert, M. ; Schulz, H. ; Stöger, T. ; Wolf, E. ; Wurst, W. ; Yildirim, A.Ö. ; Zimmer, A. ; Hrabě de Angelis, M.
Innovations in phenotyping of mouse models in the German Mouse Clinic.Slotta-Huspenina, J. ; Koch, I. ; de Leval, L. ; Keller, G. ; Klier, M. ; Bink, K. ; Kremer, M. ; Raffeld, M. ; Fend, F. ; Quintanilla-Martinez, L.
The impact of cyclin D1 mRNA isoforms, morphology and p53 in mantle cell lymphoma: P53 alterations and blastoid morphology are strong predictors of a high proliferation index.Bauer, L. ; Langer, R. ; Becker, K. ; Hapfelmeier, A. ; Ott, K. ; Novotny, A. ; Höfler, H. ; Keller, G.
Expression profiling of stem cell-related genes in neoadjuvant-treated gastric cancer: A NOTCH2, GSK3B and β-catenin gene signature predicts survival.Rumenapp, C. ; Smida, J. ; Gonzalez-Vasconcellos, I. ; Baumhoer, D. ; Malfoy, B. ; Hadj-Hamou, N.S. ; Sanli-Bonazzi, B. ; Nathrath, M. ; Atkinson, M.J. ; Rosemann, M.
Secondary radiation-induced bone tumours demonstrate a high degree of genomic instability predictive of a poor prognosis.Stross, L. ; Günther, J. ; Gasteiger, G. ; Asen, T. ; Graf, S. ; Aichler, M. ; Esposito, I. ; Busch, D.H. ; Knolle, P. ; Sparwasser, T. ; Protzer, U.
Foxp3+ regulatory T cells protect the liver from immune damage and compromise virus control during acute experimental hepatitis B virus infection in mice.Li, Z. ; Graf, N.A. ; Herrmann, K. ; Jünger, A. ; Aichler, M. ; Feuchtinger, A. ; Baumgart, A. ; Walch, A.K. ; Peschel, C. ; Schwaiger, M. ; Buck, A. ; Keller, U. ; Dechow, T.
FLT-PET is superior to FDG-PET for very early response prediction in NPM-ALK-positive lymphoma treated with targeted therapy.Vallon, M. ; Seidl, C. ; Blechert, B. ; Li, Z. ; Gilbertz, K.P. ; Baumgart, A. ; Aichler, M. ; Feuchtinger, A. ; Gaertner, F.C. ; Bruchertseifer, F. ; Morgenstern, A. ; Walch, A.K. ; Senekowitsch-Schmidtke, R. ; Essler, M.
Enhanced efficacy of combined 213Bi-DTPA-F3 and paclitaxel therapy of peritoneal carcinomatosis is mediated by enhanced induction of apoptosis and G2/M phase arrest.Slotta-Huspenina, J. ; Berg, D. ; Bauer, K. ; Wolff, C. ; Malinowsky, K. ; Bauer, L. ; Drecoll, E. ; Bettstetter, M. ; Feith, M. ; Walch, A.K. ; Höfler, H. ; Becker, K.F. ; Langer, R.
Evidence of prognostic relevant expression profiles of heat-shock proteins and glucose-regulated proteins in oesophageal adenocarcinomas.Lee, M.S. ; Waser, B. ; Reubi, J.-C. ; Pellegata, N.S.
Secretin receptor promotes the proliferation of endocrine tumor cells via the PI3K/AKT pathway.Gehrmann, M. ; Stangl, S. ; Kirschner, A. ; Foulds, G.A. ; Sievert, W. ; Doß, B.T. ; Walch, A.K. ; Pockley, A.G. ; Multhoff, G.
Immunotherapeutic targeting of membrane Hsp70-expressing tumors using recombinant human granzyme B.Balluff, B. ; Rauser, S. ; Ebert, M.P. ; Siveke, J.T. ; Höfler, H. ; Walch, A.K.
Direct molecular tissue analysis by MALDI imaging mass spectrometry in the field of gastrointestinal disease.Sabrautzki, S. ; Rubio-Aliaga, I. ; Hans, W. ; Fuchs, H. ; Rathkolb, B. ; Calzada-Wack, J. ; Cohrs, C.M. ; Klaften, M. ; Seedorf, H. ; Eck, S.H. ; Benet-Pagès, A. ; Favor, J. ; Esposito, I. ; Strom, T.M. ; Wolf, E. ; Lorenz-Depiereux, B. ; Hrabě de Angelis, M.
New mouse models for metabolic bone diseases generated by genome-wide ENU mutagenesis.Hüttemann, M. ; Lee, I. ; Gao, X. ; Pecina, P. ; Pecinova, A. ; Liu, J. ; Aras, S. ; Sommer, N. ; Sanderson, T.H. ; Tost, M. ; Neff, F. ; Aguilar-Pimentel, J.A. ; Becker, L. ; Naton, B. ; Rathkolb, B. ; Rozman, J. ; Favor, J. ; Hans, W. ; Prehn, C. ; Puk, O. ; Schrewe, A. ; Sun, M. ; Höfler, H. ; Adamski, J. ; Bekeredjian, R. ; Graw, J. ; Adler, T. ; Busch, D.H. ; Klingenspor, M. ; Klopstock, T. ; Ollert, M. ; Wolf, E. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Weissmann, N. ; Doan, J.W. ; Bassett, D.J. ; Grossman, L.I.
Cytochrome c oxidase subunit 4 isoform 2-knockout mice show reduced enzyme activity, airway hyporeactivity, and lung pathology.Waltereit, R. ; Leimer, U. ; von Bohlen und Halbach, O. ; Panke, J. ; Hölter, S.M. ; Garrett, L. ; Wittig, K. ; Schneider, M. ; Schmitt, C. ; Calzada-Wack, J. ; Neff, F. ; Becker, L. ; Prehn, C. ; Kutscherjawy, S. ; Endris, V. ; Bacon, C. ; Fuchs, H. ; Gailus-Durner, V. ; Berger, S. ; Schönig, K. ; Adamski, J. ; Klopstock, T. ; Esposito, I. ; Wurst, W. ; Hrabě de Angelis, M. ; Rappold, G. ; Wieland, T. ; Bartsch, D.
Srgap3-/- mice present a neurodevelopmental disorder with schizophrenia-related intermediate phenotypes.Fuchs, H. ; Neschen, S. ; Rozman, J. ; Rathkolb, B. ; Wagner, S. ; Adler, T. ; Alfonso, L. ; Aguilar-Pimentel, J.A. ; Becker, L. ; Bohla, A. ; Calzada-Wack, J. ; Cohrs, C.M. ; Frankó, A. ; Garrett, L. ; Glasl, L. ; Götz, A. ; Hagn, M. ; Hans, W. ; Hölter, S.M. ; Horsch, M. ; Kahle-Stephan, M. ; Kistler, M. ; Klein-Rodewald, T. ; Lengger, C. ; Ludwig, T. ; Maier, H. ; Marschall, S. ; Micklich, K. ; Möller, G. ; Naton, B. ; Neff, F. ; Prehn, C. ; Puk, O. ; Rácz, I. ; Räß, M. ; Scheerer, M. ; Schiller, E. ; Schöfer, F.H. ; Schrewe, A. ; Steinkamp, R. ; Stoeger, C. ; Treise, I. ; Willershäuser, M. ; Zimprich, A. ; Zeh, R.M. ; Adamski, J. ; Beckers, J. ; Bekeredjian, R. ; Busch, D.H. ; Favor, J. ; Graw, J. ; Katus, H.A. ; Klopstock, T. ; Ollert, M. ; Schulz, H. ; Stöger, T. ; Wurst, W. ; Yildirim, A.Ö. ; Zimmer, A. ; Wolf, E. ; Klingenspor, M. ; Gailus-Durner, V. ; Hrabě de Angelis, M.
Mouse genetics and metabolic mouse phenotyping.Saraste, A. ; Laitinen, I. ; Weidl, E. ; Wildgruber, M. ; Weber, A.W. ; Nekolla, S.G. ; Hölzlwimmer, G. ; Esposito, I. ; Walch, A.K. ; Leppänen, P. ; Lisinen, I. ; Luppa, P.B. ; Yla-Herttuala, S. ; Wester, H.J. ; Knuuti, J. ; Schwaiger, M.
Diet intervention reduces uptake of αvβ3 integrin-targeted PET tracer 18F-galacto-RGD in mouse atherosclerotic plaques.Kneissl, J. ; Keller, S. ; Lorber, T. ; Heindl, S. ; Keller, G. ; Drexler, I. ; Hapfelmeier, A. ; Höfler, H. ; Luber, B.
Association of amphiregulin with the cetuximab sensitivity of gastric cancer cell lines.Trede, D. ; Schiffler, S. ; Becker, M. ; Wirtz, S. ; Steinhorst, K. ; Strehlow, J. ; Aichler, M. ; Kobarg, J.H. ; Oetjen, J. ; Dyatlov, A. ; Heldmann, S. ; Walch, A.K. ; Thiele, H. ; Maass, P. ; Alexandrov, T.
Exploring three-dimensional matrix-assisted laser desorption/ionization imaging mass spectrometry data: Three-dimensional spatial segmentation of mouse kidney.Bauer, K. ; Nitsche, U. ; Slotta-Huspenina, J. ; Drecoll, E. ; von Weyhern, C.H. ; Rosenberg, R. ; Höfler, H. ; Langer, R.
High HSP27 and HSP70 expression levels are independent adverse prognostic factors in primary resected colon cancer.Dalke, C. ; Hölzlwimmer, G. ; Calzada-Wack, J. ; Quintanilla-Martinez, L. ; Atkinson, M.J. ; Rosemann, M.
Differences in the susceptibility to iodine131-induced thyroid tumours amongst inbred mouse strains.Baumhoer, D. ; Smida, J. ; Zillmer, S. ; Rosemann, M. ; Atkinson, M.J. ; Nelson, P.J. ; Jundt, G. ; von Luettichau, I. ; Nathrath, M.
Strong expression of CXCL12 is associated with a favorable outcome in osteosarcoma.Prade, E. ; Tobiasch, M. ; Hitkova, I. ; Schaffer, I. ; Lian, F. ; Xing, X.B. ; Tänzer, M. ; Rauser, S. ; Walch, A.K. ; Feith, M. ; Post, S. ; Röcken, C. ; Schmid, R.M. ; Ebert, M.P.A. ; Burgermeister, E.
Bile acids down-regulate caveolin-1 in esophageal epithelial cells through sterol responsive element-binding protein.Grüner, B.M. ; Hahne, H. ; Mazur, P.K. ; Trajkovic-Arsic, M. ; Maier, S.K. ; Esposito, I. ; Kalideris, E. ; Michalski, C.W. ; Kleeff, J. ; Rauser, S. ; Schmid, R.M. ; Kuster, B. ; Walch, A.K. ; Siveke, J.T.
MALDI imaging mass spectrometry for in situ proteomic analysis of preneoplastic lesions in pancreatic cancer.Staropoli, J.F. ; Haliw, L. ; Biswas, S. ; Garrett, L. ; Hölter, S.M. ; Becker, L. ; Skosyrski, S. ; Da Silva-Buttkus, P. ; Calzada-Wack, J. ; Neff, F. ; Rathkolb, B. ; Rozman, J. ; Schrewe, A. ; Adler, T. ; Puk, O. ; Sun, M. ; Favor, J. ; Rácz, I. ; Bekeredjian, R. ; Busch, D.H. ; Graw, J. ; Klingenspor, M. ; Klopstock, T. ; Wolf, E. ; Wurst, W. ; Zimmer, A. ; Lopez, E. ; Harati, H. ; Hill, E. ; Krause, D.S. ; Guide, J. ; Dragileva, E. ; Gale, E. ; Wheeler, V.C. ; Boustany, R.M. ; Brown, D.E. ; Breton, S. ; Ruether, K. ; Gailus-Durner, V. ; Fuchs, H. ; Hrabě de Angelis, M. ; Cotman, S.L.
Large-scale phenotyping of an accurate genetic mouse model of JNCL identifies novel early pathology outside the central nervous system.Heindl, S. ; Eggenstein, E. ; Keller, S. ; Kneissl, J. ; Keller, G. ; Mutze, K. ; Rauser, S. ; Gasteiger, G. ; Drexler, I. ; Hapfelmeier, A. ; Höfler, H. ; Luber, B.
Relevance of MET activation and genetic alterations of KRAS and E-cadherin for cetuximab sensitivity of gastric cancer cell lines.Seiz, L. ; Dorn, J. ; Kotzsch, M. ; Walch, A.K. ; Grebenchtchikov, N.I. ; Gkazepis, A. ; Schmalfeldt, B. ; Kiechle, M. ; Bayani, J. ; Diamandis, E.P. ; Langer, R. ; Sweep, F.C. ; Schmitt, M. ; Magdolen, V.
Stromal cell-associated expression of kallikrein-related peptidase 6 (KLK6) indicates poor prognosis of ovarian cancer patients.von Brühl, M.L. ; Stark, K. ; Steinhart, A. ; Chandraratne, S. ; Konrad, I. ; Lorenz, M. ; Khandoga, A. ; Tirniceriu, A. ; Coletti, R. ; Köllnberger, M. ; Byrne, R.A. ; Laitinen, I. ; Walch, A.K. ; Brill, A. ; Pfeiler, S. ; Manukyan, D. ; Braun, S. ; Lange, P. ; Riegger, J. ; Ware, J. ; Eckart, A. ; Haidari, S. ; Rudelius, M. ; Schulz, C. ; Echtler, K. ; Brinkmann, V. ; Schwaiger, M. ; Preissner, K.T. ; Wagner, D.D. ; Mackman, N. ; Engelmann, B. ; Massberg, S.
Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo.Tichomirowa, M.A. ; Lee, M.S. ; Barlier, A. ; Daly, A.F. ; Marinoni, I. ; Jaffrain-Rea, M.L. ; Naves, L.A. ; Rodien, P. ; Rohmer, V. ; Faucz, F.R. ; Caron, P. ; Estour, B. ; Lecomte, P. ; Borson-Chazot, F. ; Penfornis, A. ; Yaneva, M. ; Guitelman, M. ; Castermans, E. ; Verhaege, C. ; Wémeau, J.L. ; Tabarin, A. ; Fajardo Montañana, C. ; Delemer, B. ; Kerlan, V. ; Sadoul, J.L. ; Cortet Rudelli, C. ; Archambeaud, F. ; Zacharieva, S. ; Theodoropoulou, M. ; Brue, T. ; Enjalbert, A. ; Bours, V. ; Pellegata, N.S. ; Beckers, A.
Cyclin-dependent kinase inhibitor 1B (CDKN1B) gene variants in AIP mutation-negative familial isolated pituitary adenoma kindreds.Azimzadeh, O. ; Scherthan, H. ; Yentrapalli, R. ; Barjaktarovic, Z. ; Ueffing, M. ; Conrad, M. ; Neff, F. ; Calzada-Wack, J. ; Aubele, M. ; Buske, C. ; Atkinson, M.J. ; Hauck, S.M. ; Tapio, S.
Label-free protein profiling of formalin-fixed paraffin-embedded (FFPE) heart tissue reveals immediate mitochondrial impairment after ionising radiation.Grunewald, T.G. ; Ranft, A. ; Esposito, I. ; Da Silva-Buttkus, P. ; Aichler, M. ; Baumhoer, D. ; Schaefer, K.L. ; Ottaviano, L. ; Poremba, C. ; Jundt, G. ; Jürgens, H. ; Dirksen, U. ; Richter, G.H. ; Burdach, S.
High STEAP1 expression is associated with improved outcome of Ewing's sarcoma patients.Elsner, M. ; Rauser, S. ; Maier, S.K. ; Schöne, C. ; Balluff, B. ; Meding, S. ; Jung, G. ; Nipp, M. ; Sarioglu, H. ; Maccarrone, G. ; Aichler, M. ; Feuchtinger, A. ; Langer, R. ; Jütting, U. ; Feith, M. ; Kuster, B. ; Ueffing, M. ; Zitzelsberger, H. ; Höfler, H. ; Walch, A.K.
MALDI imaging mass spectrometry reveals COX7A2, TAGLN2 and S100-A10 as novel prognostic markers in Barrett's adenocarcinoma.Manook, A. ; Yousefi, B.H. ; Willuweit, A. ; Platzer, S. ; Reder, S. ; Voss, A. ; Huisman, M. ; Settles, M. ; Neff, F. ; Velden, J. ; Schoor, M. ; von der Kammer, H. ; Wester, H.J. ; Schwaiger, M. ; Henriksen, G. ; Drzezga, A..
Small-animal PET imaging of amyloid-beta plaques with [11C]PiB and its multi-modal validation in an APP/PS1 mouse model of Alzheimer's disease.Essler, M. ; Gärtner, F.C. ; Neff, F. ; Blechert, B. ; Senekowitsch-Schmidtke, R. ; Bruchertseifer, F. ; Morgenstern, A. ; Seidl, C..
Therapeutic efficacy and toxicity of 225Ac-labelled vs. 213Bi-labelled tumour-homing peptides in a preclinical mouse model of peritoneal carcinomatosis.Meding, S. ; Nitsche, U. ; Balluff, B. ; Elsner, M. ; Rauser, S. ; Schöne, C. ; Nipp, M. ; Maak, M. ; Feith, M. ; Ebert, M.P. ; Friess, H. ; Langer, R. ; Höfler, H. ; Zitzelsberger, H. ; Rosenberg, R. ; Walch, A.K.
Tumor classification of six common cancer types based on proteomic profiling by MALDI imaging.Takenaka, S. ; Möller, W. ; Semmler-Behnke, M. ; Karg, E.W. ; Wenk, A. ; Schmid, O. ; Stöger, T. ; Jennen, L. ; Aichler, M. ; Walch, A.K. ; Pokhrel, S. ; Mädler, L. ; Eickelberg, O. ; Kreyling, W.G.
Efficient internalization and intracellular translocation of inhaled gold nanoparticles in rat alveolar macrophages.Ludyga, N. ; Grünwald, B. ; Azimzadeh, O. ; Englert, S. ; Höfler, H. ; Tapio, S. ; Aubele, M.
Nucleic acids from long-term preserved FFPE tissues are suitable for downstream analyses.Berg, D. ; Wolff, C. ; Malinowsky, K. ; Tran, K. ; Walch, A.K. ; Bronger, H. ; Schuster, T. ; Höfler, H. ; Becker, K.-F.
Profiling signalling pathways in formalin-fixed and paraffin-embedded breast cancer tissues reveals cross-talk between EGFR, HER2, HER3 and uPAR.Ebert, M.P. ; Tänzer, M. ; Balluff, B. ; Burgermeister, E. ; Kretzschmar, A.K. ; Hughes, D.J. ; Tetzner, R. ; Lofton-Day, C. ; Rosenberg, R. ; Reinacher-Schick, A.C. ; Schulmann, K. ; Tannapfel, A. ; Hofheinz, R. ; Röcken, C. ; Keller, G. ; Langer, R. ; Specht, K. ; Porschen, R. ; Stöhlmacher-Williams, J. ; Schuster, T. ; Ströbel, P. ; Schmid, R.M.
TFAP2E-DKK4 and chemoresistance in colorectal cancer.Grunewald, T.G. ; Diebold, I. ; Esposito, I. ; Plehm, S. ; Hauer, K. ; Thiel, U. ; Da Silva-Buttkus, P. ; Neff, F. ; Unland, R. ; Müller-Tidow, C. ; Zobywalski, C. ; Lohrig, K. ; Lewandrowski, U. ; Sickmann, A. ; da Costa, O.P. ; Görlach, A. ; Cossarizza, A. ; Butt, E. ; Richter, G.H. ; Burdach, S.
STEAP1 is associated with the invasive and oxidative stress phenotype of Ewing tumors.Aichler, M. ; Seiler, C. ; Tost, M. ; Siveke, J. ; Mazur, P.K. ; Da Silva-Buttkus, P. ; Bartsch, D.K. ; Langer, P. ; Chiblak, S. ; Dürr, A. ; Höfler, H. ; Klöppel, G. ; Müller-Decker, K. ; Brielmeier, M. ; Esposito, I.
Origin of pancreatic ductal adenocarcinoma from atypical flat lesions: A comparative study in transgenic mice and human tissues.Kernt, M. ; Walch, A.K. ; Neubauer, A.S. ; Hirneiss, C. ; Haritoglou, C. ; Ulbig, M.W. ; Kampik, A.
Filtering blue light reduces light-induced oxidative stress, senescence, and accumulation of extracellular matrix proteins in human retinal pigment epithelium cells.Nipp, M. ; Elsner, M. ; Balluff, B. ; Meding, S. ; Sarioglu, H. ; Ueffing, M. ; Rauser, S. ; Unger, K. ; Höfler, H. ; Walch, A.K. ; Zitzelsberger, H.
S100-A10, thioredoxin, and S100-A6 as biomarkers of papillary thyroid carcinoma with lymph node metastasis identified by MALDI Imaging.Aubele, M. ; Ludyga, N. ; Braselmann, H. ; Atkinson, M.J. ; Auer, G. ; Anastasov, N.
Targeted modulation of HER receptor signaling in breast cancer using miR-21 .Schmidl, S.
The role of AID and NF-κB for B cell development and lymphomagenesis.Luber, B. ; Deplazes, J. ; Keller, G. ; Walch, A.K. ; Rauser, S. ; Eichmann, M. ; Langer, R. ; Höfler, H. ; Hegewisch-Becker, S. ; Folprecht, G. ; Wöll, E. ; Decker, T.-M. ; Endlicher, E. ; Lorenzen, S. ; Fend, F. ; Peschel, C. ; Lordick, F.
Biomarker analysis of cetuximab plus oxaliplatin/leucovorin/5-fluorouracil in first-line metastatic gastric and oesophago-gastric junction cancer: Results from a phase II trial of the Arbeitsgemeinschaft Internistische Onkologie (AIO).Baumhoer, D. ; Elsner, M. ; Smida, J. ; Zillmer, S. ; Rauser, S. ; Schoene, C. ; Balluff, B. ; Bielack, S. ; Jundt, G. ; Walch, A.K. ; Nathrath, M.
CRIP1 expression is correlated with a favorable outcome and less metastases in osteosarcoma patients.Marjanovic, G. ; Schricker, M. ; Walch, A.K. ; zur Hausen, A. ; Hopt, U.T. ; Imdahl, A. ; Makowiec, F.
Detection of lymph node involvement by cytokeratin immunohistochemistry is an independent prognostic factor after curative resection of esophageal cancer.Pallua, J.D. ; Schaefer, G. ; Bittner, L.K. ; Pezzei, C. ; Huck-Pezzei, V. ; Schoenbichler, S.A. ; Meding, S. ; Rauser, S. ; Walch, A.K. ; Handler, M. ; Netzer, M. ; Osl, M. ; Seger, M. ; Pfeifer, B. ; Baumgartner, C. ; Lindner, H. ; Kremser, L. ; Sarg, B. ; Klocker, H. ; Bartsch, G. ; Bonn, G.K. ; Huck, C.W.
Matrix-assisted laser desorption-ionization imaging mass spectrometry for direct tissue analysis.Walch, A.K. ; Rauser, S. ; Höfler, H.
MALDI imaging mass spectrometry on formalin-fixed paraffin-embedded tissues.Mutze, K. ; Langer, R. ; Schumacher, F. ; Becker, K. ; Ott, K. ; Novotny, A. ; Hapfelmeier, A. ; Höfler, H. ; Keller, G.
DNA methyltransferase 1 as a predictive biomarker and potential therapeutic target for chemotherapy in gastric cancer.Lee, M.S.
The MENX syndrome: An animal model to study the role of p27 in tumor predisposition and the response of neuroendocrine tumors to therapeutic agents.Ewald, P.S.
Untersuchungen zur intratumoralen Heterogenität der Genexpression beim Adenokarzinom des Ösophagus.Thomas, D.M. ; Wilhelm, M. ; Cleton-Jansen, A.M. ; Dirksen, U. ; Entz-Werlé, N. ; Gelderblom, H. ; Hassan, B. ; Jürgens, H. ; Koster, J. ; Kovar, H. ; Lankester, A.C. ; Lewis, I.J. ; Myklebost, O. ; Nathrath, M. ; Picci, P. ; Whelan, J.S. ; Hogendoorn, P.C.W. ; Bielack, S.S.
Workshop report on the European Bone Sarcoma Networking Meeting: Integration of clinical trials with tumor biology.Schumann, R.G. ; Eibl, K.H. ; Zhao, F. ; Scheerbaum, M. ; Scheler, R. ; Schaumberger, M.M. ; Wehnes, H. ; Walch, A.K. ; Haritoglou, C. ; Kampik, A. ; Gandorfer, A.
Immunocytochemical and ultrastructural evidence of glial cells and hyalocytes in internal limiting membrane specimens of idiopathic macular holes.Loos, M. ; Langer, R. ; Schuster, T. ; Gertler, R. ; Walch, A.K. ; Rauser, S. ; Friess, H. ; Feith, M.
Clinical significance of the costimulatory molecule B7-H1 in Barrett carcinoma.Zischka, H. ; Lichtmannegger, J. ; Schmitt, S. ; Jägemann, N. ; Schulz, S. ; Wartini, D. ; Jennen, L. ; Rust, C. ; Larochette, N. ; Galluzzi, L. ; Chajes, V. ; Bandow, N. ; Gilles, V.S. ; DiSpirito, A.A. ; Esposito, I. ; Göttlicher, M. ; Summer, K.H. ; Kroemer, G.
Liver mitochondrial membrane crosslinking and destruction in a rat model of Wilson disease.Braren, R. ; Altomonte, J. ; Settles, M. ; Neff, F. ; Esposito, I. ; Ebert, O. ; Schwaiger, M. ; Rummeny, E. ; Steingoetter, A.
Validation of preclinical multiparametric imaging for prediction of necrosis in hepatocellular carcinoma after embolization.Balluff, B. ; Schöne, C. ; Höfler, H. ; Walch, A.K.
MALDI imaging mass spectrometry for direct tissue analysis: Technological advancements and recent applications.Alexandrov, T. ; Meding, S. ; Trede, D. ; Kobarg, J.H. ; Balluff, B. ; Walch, A.K. ; Thiele, H. ; Maass, P.
Super-resolution segmentation of imaging mass spectrometry data: Solving the issue of low lateral resolution.Lian, F. ; Xing, X. ; Yuan, G. ; Schäfer, C. ; Rauser, S. ; Walch, A.K. ; Röcken, C. ; Ebeling, M. ; Wright, M.B. ; Schmid, R.M. ; Ebert, M.P. ; Burgermeister, E.
Farnesoid X receptor protects human and murine gastric epithelial cells against inflammation-induced damage.Wu, Z. ; Doondeea, J.B. ; Moghaddas Gholami, A. ; Janning, M.C. ; Lemeer, S. ; Kramer, K. ; Eccles, S.A. ; Gollin, S.M. ; Grenman, R. ; Walch, A.K. ; Feller, S.M. ; Kuster, B.
Quantitative chemical proteomics reveals new potential drug targets in head and neck cancer.Bertossi, A. ; Aichinger, M. ; Sansonetti, P. ; Lech, M. ; Neff, F. ; Pal, M. ; Wunderlich, F.T. ; Anders, H.J. ; Klein, L. ; Schmidt-Supprian, M.
Loss of Roquin induces early death and immune deregulation but not autoimmunity.Waser, B. ; Beetschen, K. ; Pellegata, N.S. ; Reubi, J.C.
Incretin receptors in non-neoplastic and neoplastic thyroid C cells in rodents and humans: Relevance for incretin-based diabetes therapy.Miederer, M. ; Molatore, S. ; Marinoni, I. ; Perren, A. ; Spitzweg, C. ; Reder, S. ; Wester, H.J. ; Buck, A.K. ; Schwaiger, M. ; Pellegata, N.S.
Functional imaging of pheochromocytoma with 68Ga-DOTATOC and 68C-HED in a genetically defined rat model of multiple endocrine neoplasia.Lee, M.S. ; Theodoropoulou, M. ; Graw, J. ; Roncaroli, F. ; Zatelli, M.C. ; Pellegata, N.S.
Levels of p27 sensitize to dual PI3K/mTOR inhibition.Balluff, B. ; Rauser, S. ; Meding, S. ; Elsner, M. ; Schöne, C. ; Feuchtinger, A. ; Schuhmacher, C. ; Novotny, A. ; Jütting, U. ; Maccarrone, G. ; Sarioglu, H. ; Ueffing, M. ; Braselmann, H. ; Zitzelsberger, H. ; Schmid, R.M. ; Höfler, H. ; Ebert, M.P. ; Walch, A.K.
MALDI imaging identifies prognostic seven-protein signature of novel tissue markers in intestinal-type gastric cancer.Wirth, E.K. ; Sheu, S.Y. ; Chiu-Ugalde, J. ; Sapin, R. ; Klein, M.O. ; Mossbrugger, I. ; Quintanilla-Martinez, L. ; Hrabě de Angelis, M. ; Krude, H. ; Riebel, T. ; Rothe, K. ; Köhrle, J. ; Schmid, K.W. ; Schweizer, U. ; Grüters, A.
Monocarboxylate transporter 8 deficiency: Altered thyroid morphology and persistent high triiodothyronine/thyroxine ratio after thyroidectomy.Langer, R. ; Rauser, S. ; Feith, M. ; Nährig, J.M. ; Feuchtinger, A. ; Friess, H. ; Höfler, H. ; Walch, A.K.
Assessment of ErbB2 (Her2) in oesophageal adenocarcinomas: Summary of a revised immunohistochemical evaluation system, bright field double in situ hybridisation and fluorescence in situ hybridisation.Schlegel, J. ; Schäfer, A. ; Zimmer, C.
Hirntumorstammzellen und Therapieresistenz in malignen Gliomen.Deininger, S.O. ; Cornett, D.S. ; Paape, R. ; Becker, M. ; Pineau, C. ; Rauser, S. ; Walch, A.K. ; Wolski, E.
Normalization in MALDI-TOF imaging datasets of proteins: Practical considerations.Timme, S. ; Schmitt, E. ; Stein, S. ; Schwarz-Finsterle, J. ; Wagner, J. ; Walch, A.K. ; Werner, M. ; Hausmann, M. ; Wiech, T.
Nuclear position and shape deformation of chromosome 8 territories in pancreatic ductal adenocarcinoma.Ebert, G. ; Poeck, H. ; Lucifora, J. ; Baschuk, N. ; Esser, K. ; Esposito, I. ; Hartmann, G. ; Protzer, U.
5' triphosphorylated small interfering RNAs control replication of hepatitis B virus and induce an interferon response in human liver cells and mice.Paron, I. ; Berchtold, S. ; Vörös, J. ; Shamarla, M. ; Erkan, M. ; Höfler, H. ; Esposito, I.
Tenascin-C enhances pancreatic cancer cell growth and motility and affects cell adhesion through activation of the integrin pathway.Straub, B.K. ; Esposito, I. ; Gotthardt, D. ; Radeleff, B. ; Antolovic, D. ; Flechtenmacher, C. ; Schirmacher, P.
IgG4-associated cholangitis with cholangiocarcinoma.Raab, M. ; Kappel, S. ; Krämer, A. ; Sanhaji, M. ; Matthess, Y. ; Kurunci-Csacsko, E. ; Calzada-Wack, J. ; Rathkolb, B. ; Rozman, J. ; Adler, T. ; Busch, D.H. ; Esposito, I. ; Fuchs, H. ; Gailus-Durner, V. ; Klingenspor, M. ; Wolf, E. ; Sänger, N. ; Prinz, F. ; Hrabě de Angelis, M. ; Seibler, J. ; Yuan, J. ; Bergmann, M. ; Knecht, R. ; Kreft, B. ; Strebhardt, K.
Toxicity modelling of Plk1-targeted therapies in genetically engineered mice and cultured primary mammalian cells.Becker, K. ; Langer, R. ; Reim, D. ; Novotny, A. ; Meyer zum Büschenfelde, C. ; Engel, J. ; Friess, H. ; Höfler, H.
Significance of histopathological tumor regression after neoadjuvant chemotherapy in gastric adenocarcinomas: A summary of 480 cases.Berg, D. ; Langer, R. ; Tran, K. ; Walch, A.K. ; Schuster, T. ; Bronger, H. ; Becker, K.F.
Protein microarray-based comparison of HER2, estrogen receptor, and progesterone receptor status in core biopsies and surgical specimens from FFPE breast cancer tissues.Vela-Chávez, T. ; Adam, P. ; Kremer, M. ; Bink, K. ; Bacon, C.M. ; Menon, G. ; Ferry, J.A. ; Fend, F. ; Jaffe, E.S. ; Quintanilla-Martinez, L.
Cyclin D1 positive diffuse large B-cell lymphoma is a post-germinal center-type lymphoma without alterations in the CCND1 gene locus.Langer, R. ; Becker, K. ; Feith, M. ; Friess, H. ; Höfler, H. ; Keller, G.
Genetic aberrations in primary esophageal melanomas: Molecular analysis of c-KIT, PDGFR, KRAS, NRAS and BRAF in a series of 10 cases.Schlitter, A.M. ; Esposito, I. ; Klöppel, G.
Klassifikation und Diagnose zystischer Pancreastumoren.Eberhardt, C. ; Amann, B. ; Feuchtinger, A. ; Hauck, S.M. ; Deeg, C.A.
Differential expression of inwardly rectifying K+ channels and aquaporins 4 and 5 in autoimmune uveitis indicates misbalance in Müller glial cell-dependent ion and water homeostasis.Azimzadeh, O. ; Scherthan, H. ; Sarioglu, H. ; Barjaktarovic, Z. ; Conrad, M. ; Vogt, A. ; Calzada-Wack, J. ; Neff, F. ; Aubele, M. ; Buske, C. ; Atkinson, M.J. ; Tapio, S.
Rapid proteomic remodeling of cardiac tissue caused by total body ionizing radiation.Ludyga, N. ; Anastasov, N. ; Gonzalez-Vasconcellos, I. ; Ram, M. ; Höfler, H. ; Aubele, M.
Impact of protein tyrosine kinase 6 (PTK6) on human epidermal growth factor receptor (HER) signalling in breast cancer.Baumhoer, D. ; Smida, J. ; Specht, K. ; Bink, K. ; Quintanilla-Martinez, L. ; Rosemann, M. ; Siggelkow, H. ; Nathrath, W.B. ; Atkinson, M.J. ; Bielack, S. ; Jundt, G. ; Nathrath, M.
Aberrant expression of the human epidermal growth factor receptor 2 oncogene is not a common feature in osteosarcoma.Abe, K. ; Fuchs, H. ; Boersma, A. ; Hans, W. ; Yu, P. ; Kalaydjiev, S. ; Klaften, M. ; Adler, T. ; Calzada-Wack, J. ; Mossbrugger, I. ; Rathkolb, B. ; Rozman, J. ; Prehn, C. ; Maraslioglu, M. ; Kametani, Y. ; Shimada, S. ; Adamski, J. ; Busch, D.H. ; Esposito, I. ; Klingenspor, M. ; Wolf, E. ; Wurst, W. ; Gailus-Durner, V. ; Katan, M. ; Marschall, S. ; Soewarto, D. ; Wagner, S. ; Hrabě de Angelis, M.
A novel N-ethyl-N-nitrosourea-induced mutation in phospholipase Cγ2 causes inflammatory arthritis, metabolic defects, and male infertility in vitro in a murine model.Bader, S.R. ; Fischer, A. ; Emrich, D. ; Jütting, U. ; Weyh, T. ; Kaspers, B. ; Matiasek, K.
Evaluation of lumbosacral nerve root conduction in chickens by electrophysiological testing including high-resolution spinal magnetic stimulation.Horsch, M. ; Seeburg, PH. ; Adler, T. ; Aguilar-Pimentel, J.A. ; Becker, L. ; Calzada-Wack, J. ; Garrett, L. ; Götz, A. ; Hans, W. ; Higuchi, M. ; Hölter, S.M. ; Naton, B. ; Prehn, C. ; Puk, O. ; Rácz, I. ; Rathkolb, B. ; Rozman, J. ; Schrewe, A. ; Adamski, J. ; Busch, D.H. ; Esposito, I. ; Graw, J. ; Ivandic, B. ; Klingenspor, M. ; Klopstock, T. ; Mempel, M. ; Ollert, M. ; Schulz, S. ; Wolf, E. ; Wurst, W. ; Zimmer, A. ; Gailus-Durner, V. ; Fuchs, H. ; Hrabě de Angelis, M. ; Beckers, J.
Requirement of the RNA-editing enzyme ADAR2 for normal physiology in mice.Sibbing, D. ; Pfeufer, A. ; Perisic, T. ; Mannes, A.M. ; Fritz-Wolf, K. ; Unwin, S. ; Sinner, M.F. ; Gieger, C. ; Gloeckner, C.J. ; Wichmann, H.-E. ; Kremmer, E. ; Schäfer, Z. ; Walch, A.K. ; Hinterseer, M. ; Näbauer, M. ; Kääb, S. ; Kastrati, A. ; Schömig, A. ; Meitinger, T. ; Bornkamm, G.W. ; Conrad, M. ; von Beckerath, N.
Mutations in the mitochondrial thioredoxin reductase gene TXNRD2 cause dilated cardiomyopathy.Costa-Guda, J. ; Marinoni, I. ; Molatore, S. ; Pellegata, N.S. ; Arnold, A.
Somatic mutation and germline sequence abnormalities in CDKN1B, encoding p27Kip1, in sporadic parathyroid adenomas.Saarikangas, J. ; Mattila, PK. ; Varjosalo, M. ; Bovellan, M. ; Hakanen, J. ; Calzada-Wack, J. ; Tost, M. ; Jennen, L. ; Rathkolb, B. ; Hans, W. ; Horsch, M. ; Hyvönen, M.E. ; Perälä, N. ; Fuchs, H. ; Gailus-Durner, V. ; Esposito, I. ; Wolf, E. ; Hrabě de Angelis, M. ; Frilander, MJ. ; Savilahti, H. ; Sariola, H. ; Sainio, K. ; Lehtonen, S. ; Taipale, J. ; Salminen, M. ; Lappalainen, P.
Missing-in-metastasis MIM/MTSS1 promotes actin assembly at intercellular junctions and is required for integrity of kidney epithelia.Lagarrigue, M. ; Becker, M. ; Lavigne, R. ; Deininger, S.O. ; Walch, A.K. ; Aubry, F. ; Suckau, D. ; Pineau, C.
Revisiting rat spermatogenesis with MALDI imaging at 20- μm resolution.Fuchs, H. ; Gailus-Durner, V. ; Adler, T. ; Aguilar-Pimentel, J.A. ; Becker, L. ; Calzada-Wack, J. ; Da Silva-Buttkus, P. ; Neff, F. ; Götz, A.A. ; Hans, W. ; Hölter, S.M. ; Horsch, M. ; Kastenmüller, G. ; Kemter, E. ; Lengger, C. ; Maier, H. ; Matloka, M. ; Möller, G. ; Naton, B. ; Prehn, C. ; Puk, O. ; Rácz, I. ; Rathkolb, B. ; Römisch-Margl, W. ; Rozman, J. ; Wang-Sattler, R. ; Schrewe, A. ; Stoeger, C. ; Tost, M. ; Adamski, J. ; Aigner, B. ; Beckers, J. ; Behrendt, H. ; Busch, D.H. ; Esposito, I. ; Graw, J. ; Illig, T. ; Ivandic, B. ; Klingenspor, M. ; Klopstock, T. ; Kremmer, E. ; Mempel, M. ; Neschen, S. ; Ollert, M. ; Schulz, S. ; Suhre, K. ; Wolf, E. ; Wurst, W. ; Zimmer, A. ; Hrabě de Angelis, M.
Mouse phenotyping.González-Vasconcellos, I.M. ; Domke, T.A.J. ; Kuosaite, V. ; Esposito, I. ; Sanli-Bonazzi, B. ; Nathrath, M. ; Atkinson, M.J. ; Rosemann, M.
Differential effects of genes of the Rb1 signalling pathway on osteosarcoma incidence and latency in alpha-particle irradiated mice.Wolff, C. ; Malinowsky, K. ; Berg, D. ; Schragner, K. ; Schuster, T: ; Walch, A.K. ; Bronger, H. ; Höfler, H. ; Becker, K.F.
Signalling networks associated with urokinase-type plasminogen activator (uPA) and its inhibitor PAI-1 in breast cancer tissues: New insights from protein microarray analysis.Marinoni, I. ; Pellegata, N.S.
p27kip1: A new multiple endocrine neoplasia gene?Stangl, S. ; Gehrmann, M. ; Dressel, R. ; Alves, F. ; Dullin, C. ; Themelis, G. ; Ntziachristos, V. ; Staeblein, E. ; Walch, A.K. ; Winkelmann, I. ; Multhoff, G.
In vivo imaging of CT26 mouse tumours by using cmHsp70.1 monoclonal antibody.Balluf, B. ; Herrmann, K. ; Höfler, H. ; Walch, A.K. ; Ebert, M.
Classification of HER2/neu Status in Gastric cancer using a Breast Cancer Derived Proteome Classifier.Rauser, S. ; Deininger, S.O. ; Suckau, D. ; Höfler, H. ; Walch, A.K.
Approaching MALDI molecular imaging for clinical proteomic research: Current state and fields of application.Erben, R.G. ; Zeitz, U. ; Weber, K. ; Stierstorfer, B. ; Wolf, G. ; Schmahl, W. ; Balling, R. ; Quintanilla-Martinez, L.
A non-functioning vitamin D receptor predisposes to leukaemoid reactions in mice.Rodriguez, N. ; Dietrich, H. ; Mossbrugger, I. ; Weintz, G. ; Scheller, J. ; Hammer, M. ; Quintanilla-Martinez, L. ; Rose-John, S. ; Miethke, T. ; Lang, R.
Increased inflammation and impaired resistance to Chlamydophila pneumoniae infection in Dusp1(-/-) mice: Critical role of IL-6.Langer, R. ; Geissinger, E. ; Rudiger, T. ; von Schilling, C. ; Ott, G. ; Mandl-Weber, S. ; Quintanilla-Martinez, L. ; Fend, F.
Peripheral T-cell lymphoma with progression to a clonally related, Epstein Barr Virus plus, cytotoxic aggressive T-cell lymphoma: Evidence for secondary EBV infection of an established malignant T-cell clone.Doß, B.T.M.
Generation of an expression system for human granzyme B and analysis of the in vitro and in vivo efficiency.Tost, M.
Einfluss von Selenoproteinen auf die Kras vermittelte Karzinogenese des Pankreas.Ritterswürden, D.
Mammakarzinom: Histopathologische und prognostische Bedeutung der Gene HER-2/neu, GRB-7 und PTK-6.Walch, A.K.
Matrix-assisted laser desorption/ionization (MALDI) imaging mass spectrometry (IMS) is a powerful tool for investigating .Ludyga, N. ; Anastasov, N. ; Vasconcellos, I.G. ; Hoefler, H. ; Aubele, M.
PTK6 and HER receptor signalling in Breast Cancer.Calzada-Wack, J. ; Wagner, S. ; Rosemann, M. ; Becker, L. ; Tost, M. ; Da Silva-Buttkus, P. ; Neff, F. ; Hrabě de Angelis, M. ; Esposito, I.
Morphological and molecular characterization of a novel mouse mutant for the peripheral myelin protein 22 (Pmp22 gene)- Associated with Peripheral Neuropathy. .Paron, I. ; Berchtold, S. ; Tost, M. ; Shamarla, M. ; Esposito, I.
Tenascin-C affects pancreatic cancer migration and invasion and interferes with fibronectin adhesive function.Paron, I. ; Berchtold, S. ; Shamarla, M. ; Esposito, I.
Epithelial-stromal interaction in pancreatic cancer: The role of Collagen type V and Tenascin-C .Nipp, M. ; Elsner, M. ; Braselmann, H. ; Rauser, S. ; Walch, A.K. ; Zitzelsberger, H.
Methodenkopplung bildgebender Massenspektrometrie (MALDI-IMS) und arraybasierter vergleichender genomischer Hybridisierung (aCGH) am papillären Schilddrüsenkarzinom.Aubele, M. ; Anastasov, N. ; Braselmann, H. ; Auer, G. ; Atkinson, M.J.
Influence of miRNA expression on radiation response and HER receptor signalling in breast cancer cells .Aubele, M. ; Ludyga, N. ; Braselmann, H. ; Anastasov, N. ; Bartlett, J.M.S. ; Auer, G. ; Walch, A.K. ; Höfler, H.
Protein tyrosine kinase 6 (PTK6): its role in HER receptor signalling and breast cancer .Ergin, B. ; Meding, S. ; Langer, R. ; Kap, M. ; Viertler, C. ; Schott, C. ; Ferch, U. ; Riegman, P. ; Zatloukal, K. ; Walch, A.K. ; Becker, K.F.
Proteomic analysis of PAXgene-fixed tissues.Bauer, V.L. ; Hieber, L. ; Schäffner, Q. ; Weber, J. ; Braselmann, H. ; Huber, R. ; Walch, A.K. ; Zitzelsberger, H.
Establishment and molecular cytogenetic characterization of a cell culture model of head and neck squamous cell carcinoma (HNSCC).Langer, R. ; Mutze, K. ; Becker, K. ; Feith, M. ; Ott, K. ; Höfler, H. ; Keller, G.
Expression of class I histone deacetylases (HDAC1 and HDAC2) in oesophageal adenocarcinomas: An immunohistochemical study.Rauser, S. ; Langer, R. ; Tschernitz, S. ; Gais, P. ; Jütting, U. ; Feith, M. ; Höfler, H. ; Walch, A.K.
High number of CD45RO+ tumor infiltrating lymphocytes is an independent prognostic factor in non-metastasized (stage I-IIA) esophageal adenocarcinoma.Molatore, S. ; Liyanarachchi, S. ; Irmler, M. ; Perren, A. ; Mannelli, M. ; Ercolino, T. ; Beuschlein, F. ; Jarzab, B. ; Wloch, J. ; Ziaja, J. ; Zoubaa, S. ; Neff, F. ; Beckers, J. ; Höfler, H. ; Atkinson, M.J. ; Pellegata, N.S.
Pheochromocytoma in rats with multiple endocrine neoplasia (MENX) shares gene expression patterns with human pheochromocytoma.Becker, K.-F. ; Berg, D. ; Malinowsky, K. ; Wolff, C. ; Ergin, B. ; Meding, S. ; Walch, A.K. ; Höfler, H.
Neues zur Proteinanalytik archivierter Gewebeproben.Herbert, Z. ; Rauser, S. ; Williams, L. ; Kapan, N. ; Güntner, M: ; Walch, A.K. ; Boyan, G.
Developmental expression of neuromodulators in the central complex of the grasshopper Schistocerca gregaria.Hipp, S. ; Berg, D. ; Ergin, B. ; Schuster, T. ; Hapfelmeier, A. ; Walch, A.K. ; Avril, S. ; Schmalfeldt, B. ; Höfler, H. ; Becker, K.F.
Interaction of Snail and p38 mitogen-activated protein kinase results in shorter overall survival of ovarian cancer patients.Molatore, S. ; Marinoni, I. ; Lee, M.S. ; Pulz, E. ; Ambrosio, M.R. ; degli Uberti, E.C. ; Zatelli, M.C. ; Pellegata, N.S.
A novel germline CDKN1B mutation causing multiple endocrine tumors: Clinical, genetic and functional characterization.Jiang, X.H. ; Gillen, S. ; Esposito, I. ; Giese, N.A. ; Michalski, C.W. ; Friess, H. ; Kleeff, J.
Reduced expression of the membrane skeleton protein beta1-spectrin (SPTBN1) is associated with worsened prognosis in pancreatic cancer.Pechloff, K. ; Holch, J. ; Ferch, U. ; Schweneker, M. ; Brunner, K. ; Kremer, M. ; Sparwasser, T. ; Quintanilla-Martinez, L. ; Zimber-Strobl, U. ; Streubel, B. ; Gewies, A. ; Peschel, C. ; Ruland, J.
The fusion kinase ITK-SYK mimics a T cell receptor signal and drives oncogenesis in conditional mouse models of peripheral T cell lymphoma.Balluff, B. ; Elsner, M. ; Kowarsch, A. ; Rauser, S. ; Meding, S. ; Schuhmacher, C. ; Feith, M. ; Herrmann, K. ; Röcken, C. ; Schmid, R.M. ; Höfler, H. ; Walch, A.K. ; Ebert, M.P.
Classification of HER2/neu status in gastric cancer using a breast-cancer derived proteome classifier.Rasper, M. ; Schäfer, A. ; Piontek, G. ; Teufel, J. ; Brockhoff, G. ; Ringel, F. ; Heindl, S. ; Zimmer, C. ; Schlegel, J.
Aldehyde dehydrogenase 1 positive glioblastoma cells show brain tumor stem cell capacity.Hauck, S.M. ; Dietter, J. ; Kramer, R.L. ; Hofmaier, F. ; Zipplies, J.K. ; Amann, B. ; Feuchtinger, A. ; Deeg, C.A. ; Ueffing, M.
Deciphering membrane-associated molecular processes in target tissue of autoimmune uveitis by label-free quantitative mass spectrometry.Rüschoff, J. ; Dietel, M. ; Baretton, G. ; Arbogast, S. ; Walch, A.K. ; Monges, G. ; Chenard, M.-P. ; Penault-Llorca, F. ; Nagelmeier, I. ; Schlake, W. ; Höfler, H. ; Kreipe, H.H.
HER2 diagnostics in gastric cancer-guideline validation and development of standardized immunohistochemical testing.Smida, J. ; Baumhoer, D. ; Rosemann, M. ; Walch, A.K. ; Bielack, S. ; Poremba, C. ; Remberger, K. ; Korsching, E. ; Scheurlen, W. ; Dierkes, C. ; Burdach, S. ; Jundt, G. ; Atkinson, M.J. ; Nathrath, M.
Genomic alterations and allelic imbalances are strong prognostic predictors in osteosarcoma.Molatore, S. ; Kiermaier, E. ; Jung, C.B. ; Lee, M.S. ; Pulz, E. ; Höfler, H. ; Atkinson, M.J. ; Pellegata, N.S.
Characterization of a naturally-occurring p27 mutation predisposing to multiple endocrine tumors.Azimzadeh, O. ; Barjaktarovic, Z. ; Aubele, M. ; Calzada-Wack, J. ; Sarioglu, H. ; Atkinson, M.J. ; Tapio, S.
Formalin-fixed paraffin-embedded (FFPE) proteome analysis using gel-free and gel-based proteomics.Aubele, M. ; Spears, M. ; Ludyga, N. ; Braselmann, H. ; Feuchtinger, A. ; Taylor, K.J. ; Lindner, K. ; Auer, G. ; Stering, K. ; Höfler, H. ; Schmitt, M. ; Bartlett, J.M.S.
In situ quantification of HER2-protein tyrosine kinase 6 (PTK6) protein-protein complexes in paraffin sections from breast cancer tissues.Molatore, S. ; Pellegata, N.S.
The MENX syndrome and p27: Relationships with multiple endocrine neoplasia.Wagner, S. ; Calzada-Wack, J. ; Rosemann, M. ; Becker, L. ; Tost, M. ; Silva-Buttkus, P. ; Klein-Rodewald, T. ; Fuchs, H. ; Neff, F. ; Hrabě de Angelis, M. ; Esposito, I.
Charakterisierung von ENU-Mausmutanten. Tiermodelle für menschliche Erkrankungen mittels morphologischer und molekularer Methoden.Berg, D. ; Bronger, H. ; Walch, A.K. ; Höfler, H. ; Becker, K.F.
Analyse von Signalwegen in formalinfixierten Brustkrebsgeweben.Langer, R. ; Ott, K. ; Feith, M. ; Lordick, F. ; Specht, K. ; Becker, K. ; Höfler, H.
High pretherapeutic thymidylate synthetase and MRP-1 protein levels are associated with nonresponse to neoadjuvant chemotherapy in oesophageal adenocarcinoma patients.Mutze, K. ; Langer, R. ; Becker, K. ; Ott, K. ; Novotny, A. ; Luber, B. ; Hapfelmeier, A. ; Göttlicher, M. ; Höfler, H. ; Keller, G.
Histone deacetylase (HDAC) 1 and 2 expression and chemotherapy in gastric cancer.Rauser, S. ; Marquardt, C. ; Balluff, B. ; Deininger, S.O. ; Albers, C. ; Belau, E. ; Hartmer, R. ; Suckau, D. ; Specht, K. ; Ebert, M.P. ; Schmitt, M. ; Aubele, M. ; Höfler, H. ; Walch, A.K.
Classification of HER2 receptor status in breast cancer tissues by MALDI imaging mass spectrometry.Echtler, K. ; Stark, K. ; Lorenz, M. ; Kerstan, S. ; Walch, A.K. ; Jennen, L. ; Rudelius, M. ; Seidl, S. ; Kremmer, E. ; Emambokus, N.R. ; von Bruehl, M.L. ; Frampton, J. ; Isermann, B. ; Genzel-Boroviczény, O. ; Schreiber, C. ; Mehilli, J. ; Kastrati, A. ; Schwaiger, M. ; Shivdasani, R.A. ; Massberg, S.
Platelets contribute to postnatal occlusion of the ductus arteriosus.Morgan, H. ; Beck, T. ; Blake, A. ; Gates, H. ; Adams, N. ; Debouzy, G. ; Leblanc, S. ; Lengger, C. ; Maier, H. ; Melvin, D. ; Meziane, H. ; Richardson, D. ; Wells, S. ; White, J. ; Wood, J. ; EUMODIC Consortium (Hrabě de Angelis, M. ; Gailus-Durner, V. ; Fuchs, H. ; Adler, T. ; Aguilar-Pimentel, J.A. ; Becker, L. ; Beckeredjian, R ; Busch, D.H. ; Calzada-Wack, J. ; Da Silva-Buttkus, P. ; Esposito, I. ; Favor, J. ; Fleischmann, W. ; Garrett, L. ; Glasl, L. ; Götz, A. ; Graw, J. ; Hans, W, ; Hölter, S.M. ; Ivandic, B. ; Katus, H.A. ; Klingenspor, M. ; Klopstock, T. ; Lengger, C. ; Ludwig, T. ; Maier, H. ; Micklich, K. ; Minxuan, S. ; Naton, B. ; Neff, F. ; Ollert, M. ; Puk, O. ; Quintanilla-Fend, L. ; Rácz, I. ; Rathkolb, B. ; Rozman, J. ; Schäble, K.-H. ; Schiller, E. ; Schrewe, A. ; Steinkamp, R. ; Stoeger, C. ; Stöger, T. ; Schulz, S. ; Tost, M. ; Treise, I. ; Vogt Weisenhorn, D.M. ; Willershäuser, M. ; Wolf, E. ; Zimprich, A. ; Wurst, W. ; Zeh, R.M. ; Zimmer, A.) ; Hrabě de Angelis, M. ; Brown, S. ; Hancock, J.M. ; Mallon, A.M.
EuroPhenome: A repository for high-throughput mouse phenotyping data.Hormannsperger, G. ; Clavel, T. ; Hoffmann, M. ; Reiff, C. ; Kelly, D. ; Loh, G. ; Blaut, M. ; Hoelzlwimmer, G. ; Haller, D.
Posttranslational inhibition of proinflammatory chemokine secretion in intestinal epithelial cells implications for specific IBD indications.Shyla, A. ; Hölzlwimmer, G. ; Calzada-Wack, J. ; Bink, K. ; Tischenko, O. ; Guilly, M.N. ; Chevillard, S. ; Samson, E. ; Graw, J. ; Atkinson, M.J. ; Pellegata, N.S.
Allelic loss of chromosomes 8 and 19 in MENX-associated rat pheochromocytoma.Unger, K. ; Wienberg, J. ; Riches, A. ; Hieber, L. ; Walch, A.K. ; Brown, A. ; O'Brien, P.C. ; Briscoe, C. ; Gray, L. ; Rodriguez, E. ; Jackl, G. ; Knijnenburg, J. ; Tallini, G. ; Ferguson-Smith, M. ; Zitzelsberger, H.
Novel gene rearrangements in transformed breast cells identified by high-resolution breakpoint analysis of chromosomal aberrations.Anastasov, N. ; Bonzheim, I. ; Rudelius, M. ; Klier, M. ; Dau, T. ; Angermeier, D. ; Duyster, J. ; Pittaluga, S. ; Fend, F. ; Raffeld, M. ; Quintanilla-Martinez, L.
C/EBPβ expression in ALK-positive anaplastic large cell lymphomas (ALCL) is required for cell proliferation and is induced by the STAT3 signaling pathway.Abiatari, I. ; Esposito, I. ; de Oliveira, T. ; Felix., K. ; Xin, H. ; Penzel, R. ; Giese, T. ; Friess, H. ; Kleeff, J.
Moesin dependent cytoskeleton remodeling is associated with an anaplastic phenotype of pancreatic cancer.Rosemann, M. ; Ivashkevich, A. ; Favor, J. ; Dalke, C. ; Hölter, S.M. ; Becker, L. ; Rácz, I. ; Bolle, I. ; Klempt, M. ; Rathkolb, B. ; Kalaydjiev, S. ; Adler, T. ; Aguilar, A. ; Hans, W. ; Horsch, M. ; Rozman, J. ; Calzada-Wack, J. ; Kunder, S. ; Naton, B. ; Gailus-Durner, V. ; Fuchs, H. ; Schulz, S. ; Beckers, J. ; Busch, D.H. ; Burbach, J.P. ; Smidt, M.P. ; Quintanilla-Martinez, L. ; Esposito, I. ; Klopstock, T. ; Klingenspor, M. ; Ollert, M. ; Wolf, E. ; Wurst, W. ; Zimmer, A. ; Hrabě de Angelis, M. ; Atkinson, M.J. ; Heinzmann, U. ; Graw, J.
Microphthalmia, parkinsonism, and enhanced nociception in Pitx3(416insG ) mice.Ruseva, Z. ; Geiger, P.X. ; Hutzler, P. ; Kotzsch, M. ; Luber, B. ; Schmitt, M. ; Gross, E. ; Reuning, U.
Tumor suppressor KAI1 affects integrin alphavbeta3-mediated ovarian cancer cell adhesion, motility, and proliferation.Ruseva, Z. ; Geiger, P.X. ; Hutzler, P. ; Kotzsch, M. ; Luber, B. ; Schmitt, M. ; Gross, E. ; Reuning, U.
Tumor suppressor KAI1 affects integrin αvβ3-mediated ovarian cancer cell adhesion, motility, and proliferation.Becker, K.F. ; Walch, A.K. ; Ueffing, M.
Protein analysis of tissues - current views and clinical perspectives.Aubele, M. ; Vidojkovic, S. ; Braselmann, H. ; Ritterswürden, D. ; Auer, G. ; Atkinson, M.J. ; Tapio, S. ; Höfler, H. ; Rauser, S. ; Bartlett, J.M.
Overexpression of PTK6 (breast tumor kinase) protein - a prognostic factor for long-term breast cancer survival - is not due to gene amplification.Laitinen, I. ; Saraste, A. ; Weidl, E. ; Poethko, T. ; Weber, A.W. ; Nekolla, S.G. ; Leppänen, P. ; Yla-Herttuala, S. ; Hölzlwimmer, G. ; Walch, A.K. ; Esposito, I. ; Wester, H.J. ; Knuuti, J. ; Schwaiger, M.
Evaluation of ανβ₃ integrin-targeted positron emission tomography tracer ¹⁸F-galacto-RGD for imaging of vascular inflammation in atherosclerotic mice.Hipp, S. ; Walch, A.K. ; Schuster, T. ; Losko, S. ; Laux, H. ; Bolton, T. ; Höfler, H. ; Becker, K.F.
Activation of epidermal growth factor receptor results in snail protein but not mRNA over-expression in endometrial cancer.Lohmann, C. ; Muschaweckh, A. ; Kirschnek, S. ; Jennen, L. ; Wagner, H. ; Häcker, G.
Induction of tumor cell apoptosis or necrosis by conditional expression of cell death proteins: Analysis of cell death pathways and in vitro immune stimulatory potential.Rauser, S. ; Höfler, H. ; Walch, A.K.
In-situ-Proteomanalyse von Geweben: Mittels bildgebender Massenspektrometrie (MALDI Imaging)Rieger, S. ; Senghaas, N. ; Walch, A.K. ; Köster, R.W.
Cadherin-2 controls directional chain migration of cerebellar granule neurons.Werner, T. ; Hoermannsperger, G. ; Schuemann, K. ; Hölzlwimmer, G. ; Tsuji, S. ; Haller, D.
Intestinal epithelial cell proteome from wild-type and TNF{Delta}ARE/WT mice: Effect of iron on the development of chronic ileitis.Abiatari, I. ; DeOliveira, T. ; Kerkadze, V. ; Schwager, C. ; Esposito, I. ; Giese, N.A. ; Huber, P. ; Bergman, F. ; Abdollahi, A. ; Friess, H. ; Kleeff, J.
Consensus transcriptome signature of perineural invasion in pancreatic carcinoma.Mihaljevic, A.L. ; Esposito, I. ; Michalski, C.W. ; Kleeff, J. ; Friess, H.
Defining new pancreatic tumour entities by molecular analysis.Erkan, M. ; Reiser-Erkan, C. ; Michalski, C.W. ; Deucker, S. ; Sauliunaite, D. ; Streit, S. ; Esposito, I. ; Friess, H. ; Kleeff, J.
Cancer-stellate cell interactions perpetuate the hypoxia-fibrosis cycle in pancreatic ductal adenocarcinoma.Puk, O. ; Dalke, C. ; Calzada-Wack, J. ; Ahmad, N. ; Klaften, M. ; Wagner, S. ; Hrabě de Angelis, M. ; Graw, J.
Reduced corneal thickness and enlarged anterior chamber in a novel ColVIIIa2(G257D) mutant mouse.Raffegerst, S.H. ; Hölzlwimmer, G. ; Kunder, S. ; Mysliwietz, J. ; Quintanilla-Martinez, L. ; Schendel, D.J.
Diverse hematological malignancies including hodgkin-like lymphomas develop in chimeric MHC class II transgenic mice.Reers, C. ; Erbel, S. ; Esposito, I. ; Schmied, B. ; Büchler, M.W. ; Nawroth, P.P. ; Ritzel, R.A.
Impaired islet turnover in human donor pancreata with aging.Robel, S. ; Mori, T. ; Zoubaa, S. ; Schlegel, J. ; Sirko, S. ; Faissner, A. ; Goebbels, S. ; Dimou, L. ; Götz, M.
Conditional deletion of β1-integrin in astroglia causes partial reactive gliosis.Anastasov, N. ; Klier, M. ; Koch, I. ; Angermeier, D. ; Höfler, H. ; Fend, F. ; Quintanilla-Martinez, L.
Efficient shRNA delivery into B and T lymphoma cells using lentiviral vector-mediated transfer.Hormannsperger, G. ; Clavel, T. ; Hoffmann, M. ; Reiff, C. ; Kelly, D. ; Loh, G. ; Blaut, M. ; Hölzlwimmer, G. ; Laschinger, M. ; Haller, D.
Post-translational inhibition of IP-10 secretion in IEC by probiotic bacteria: impact on chronic inflammation.Horn, T.
Die Bedeutung der aktivierenden Mutation JAK2 V617F bei chronisch-myeloproliferativen Syndromen.Gailus-Durner, V. ; Fuchs, H. ; Adler, T. ; Aguilar-Pimentel, J.A. ; Becker, L. ; Bolle, I. ; Calzada-Wack, J. ; Dalke, C. ; Ehrhardt, N. ; Ferwagner, B. ; Hans, W, ; Hölter, S.M. ; Hölzlwimmer, G. ; Horsch, M. ; Javaheri, A. ; Kallnik, M. ; Kling, E. ; Lengger, C. ; Mörth, C. ; Mossbrugger, I. ; Naton, B. ; Prehn, C. ; Puk, O. ; Rathkolb, B. ; Rozman, J. ; Schrewe, A. ; Thiele, F. ; Adamski, J. ; Aigner, B. ; Behrendt, H. ; Busch, D.H. ; Favor, J. ; Graw, J. ; Heldmaier, G. ; Ivandic, B. ; Katus, H.A. ; Klingenspor, M. ; Klopstock, T. ; Kremmer, E. ; Ollert, M. ; Quintanilla-Martinez, L. ; Schulz, H. ; Wolf, E. ; Wurst, W. ; Hrabě de Angelis, M.
Systemic first-line phenotyping.Renström, J. ; Istvanffy, R. ; Gauthier, K. ; Shimono, A. ; Mages, J. ; Jardon-Alvarez, A. ; Kröger, M. ; Schiemann, M. ; Busch, D.H. ; Esposito, I. ; Lang, R. ; Peschel, C. ; Oostendorp, R.A.
Secreted frizzled-related protein 1 extrinsically regulates cycling activity and maintenance of hematopoietic stem cells.Peters, D.D. ; Lepikhov, K. ; Rodenacker, K. ; Marschall, S. ; Boersma, A. ; Hutzler, P. ; Scherb, H. ; Walter, J. ; Hrabě de Angelis, M.
Effect of IVF and laser zona dissection on DNA methylation pattern of mouse zygotes.Puk, O. ; Esposito, I. ; Söker, T. ; Löster, J. ; Budde, B. ; Nürnberg, P. ; Michel-Soewarto, D. ; Fuchs, H. ; Wolf, E. ; Hrabě de Angelis, M. ; Graw, J.
A new Fgf10 mutation in the mouse leads to atrophy of the harderian gland and slit-eye phenotype in heterozygotes: A novel model for dry-eye disease?Xing, X. ; Burgermeister, E. ; Geisler, F. ; Einwächter, H. ; Fan, L. ; Hiber, M. ; Rauser, S. ; Walch, A.K. ; Röcken, C. ; Ebeling, M. ; Wright, M.B. ; Schmid, R.M. ; Ebert, M.P.
Hematopoietically expressed homeobox is a target gene of farnesoid X receptor in chenodeoxycholic acid-induced liver hypertrophy.Gailus-Durner, V. ; Fuchs, H. ; Adler, T. ; Aguilar-Pimentel, J.A. ; Becker, L. ; Bolle, I. ; Calzada-Wack, J. ; Dalke, C. ; Ehrhardt, N. ; Ferwagner, B. ; Hans, W. ; Hölter, S.M. ; Hölzlwimmer, G. ; Horsch, M. ; Javaheri, A. ; Kallnik, M. ; Kling, E. ; Lengger, C. ; Mörth, C. ; Mossbrugger, I. ; Naton, B. ; Prehn, C. ; Puk, O. ; Rathkolb, B. ; Rozman, J. ; Schrewe, A. ; Thiele, F. ; Adamski, J. ; Aigner, B. ; Behrendt, H. ; Busch, D.H. ; Favor, J. ; Graw, J. ; Heldmaier, G. ; Ivandic, B. ; Katus, H.A. ; Klingenspor, M. ; Klopstock, T. ; Kremmer, E. ; Ollert, M. ; Quintanilla-Martinez, L. ; Schulz, S. ; Wolf, E. ; Wurst, W. ; Hrabě de Angelis, M.
Systemic first-line phenotyping.Deplazes, J. ; Fuchs, M. ; Rauser, S. ; Genth, H. ; Lengyel, E. ; Busch, R. ; Luber, B.
Rac1 and Rho contribute to the migratory and invasive phenotype associated with somatic E-cadherin mutation.Roselli, F. ; Hutzler, P. ; Wegerich, Y. ; Livrea, P. ; Almeida, O.F.
Disassembly of shank and homer synaptic clusters is driven by soluble β-amyloid₁₋₄₀ through divergent NMDAR-dependent signalling pathways.Sölder, E. ; Rohr, I. ; Kremser, C. ; Hutzler, P. ; Debbage, P.L.
Imaging of placental transport mechanisms: A review.Sölder, E. ; Kremser, C. ; Rohr, I. ; Hutzler, P.J.S. ; Debbage, P.
Molecular mapping deep within a living human organ: Analysis of microvessel function on the timescale of seconds and with sub-micrometre spatial resolution.Khan, M.D.H. ; Klein, D. ; Mossbrugger, I. ; Oesterle, D. ; Csanády, G.A. ; Quintanilla-Martinez, L. ; Filser, J.G.
Is propylene oxide induced cell proliferation in rat nasal respiratory epithelium mediated by a severe depletion of water-soluble non-protein thiol?Schneider, M. ; Förster, H. ; Boersma, A. ; Seiler, A. ; Wehnes, H. ; Sinowatz, F. ; Neumüller, C. ; Deutsch, M.J. ; Walch, A.K. ; Hrabě de Angelis, M. ; Wurst, W. ; Ursini, F. ; Roveri, A. ; Maleszewski, M. ; Maiorino, M. ; Conrad, M.
Mitochondrial glutathione peroxidase 4 disruption causes male infertility.Noll, S. ; Hampp, G. ; Bausbacher, H. ; Pellegata, N.S. ; Kranz, H.
Site-directed mutagenesis of multi-copy-number plasmids: Red/ET recombination and unique restriction site elimination.Schulz, D.M. ; Böllner, C. ; Thomas, G. ; Atkinson, M.J. ; Esposito, I. ; Höfler, H. ; Aubele, M.
Identification of differentially expressed proteins in triple-negative breast carcinomas using DIGE and mass spectrometry.Khasawneh, J. ; Schulz, M.D. ; Walch, A.K. ; Rozman, J. ; Hrabě de Angelis, M. ; Klingenspor, M. ; Buck, A. ; Schwaiger, M. ; Saur, D. ; Schmid, R.M. ; Klöppel, G. ; Sipos, B. ; Greten, F.R. ; Arkan, M.C.
Inflammation and mitochondrial fatty acid beta-oxidation link obesity to early tumor promotion.Herrmann, K. ; Walch, A.K. ; Balluff, B. ; Tänzer, M. ; Höfler, H. ; Krause, B.J. ; Schwaiger, M. ; Friess, H. ; Schmid, R.M. ; Ebert, M.P.
Proteomic and metabolic prediction of response to therapy in gastrointestinal cancers.Richter, G.H.S. ; Plehm, S. ; Fasan, A. ; Rössler, S. ; Unland, R. ; Bennani-Baiti, I.M. ; Hotfilder, M. ; Löwel, D. ; von Luettichau, I. ; Mossbrugger, I. ; Quintanilla-Martinez, L. ; Kovar, H. ; Staege, M.S. ; Müller-Tidow, C. ; Burdach, S.
EZH2 is a mediator of EWS/FLI1 driven tumor growth and metastasis blocking endothelial and neuro-ectodermal differentiation.Alves, C.C. ; Carneiro, F. ; Hoefler, H. ; Becker, K.-F.
Role of the epithelial-mesenchymal transition regulator Slug in primary human cancers.Enard, W. ; Gehre, S. ; Hammerschmidt, K. ; Hölter, S.M. ; Blass, T. ; Somel, M. ; Brückner, M.K. ; Schreiweis, C. ; Winter, C. ; Sohr, R. ; Becker, L. ; Wiebe, V. ; Nickel, B. ; Giger, T. ; Müller, U. ; Groszer, M. ; Adler, T. ; Aguilar, A. ; Bolle, I. ; Calzada-Wack, J. ; Dalke, C. ; Ehrhardt, N. ; Favor, J. ; Fuchs, H. ; Gailus-Durner, V. ; Hans, W. ; Hölzlwimmer, G. ; Javaheri, A. ; Kalaydjiev, S. ; Kallnik, M. ; Kling, E. ; Kunder, S. ; Moßbrugger, I. ; Naton, B. ; Rácz, I. ; Rathkolb, B. ; Rozman, J. ; Schrewe, A. ; Busch, D.H. ; Graw, J. ; Ivandic, B. ; Klingenspor, M. ; Klopstock, T. ; Ollert, M. ; Quintanilla-Martinez, L. ; Schulz, S. ; Wolf, E. ; Wurst, W. ; Zimmer, A. ; Fisher, S.E. ; Morgenstern, R. ; Arendt, T. ; Hrabě de Angelis, M. ; Fischer, J. ; Schwarz, J. ; Pääbo, S.
A humanized version of Foxp2 affects cortico-basal ganglia circuits in mice.Fuchs, H. ; Gailus-Durner, V. ; Adler, T. ; Aguilar-Pimentel, J.A. ; Becker, L. ; Bolle, I. ; Brielmeier, M. ; Calzada-Wack, J. ; Dalke, C. ; Ehrhardt, N. ; Fasnacht, N. ; Ferwagner, B. ; Frischmann, U. ; Hans, W. ; Hölter, S.M. ; Hölzlwimmer, G. ; Horsch, M. ; Javaheri, A. ; Kallnik, M. ; Kling, E. ; Lengger, C. ; Maier, H. ; Mossbrugger, I. ; Mörth, C. ; Naton, B. ; Nöth, U. ; Pasche, B. ; Prehn, C. ; Przemeck, G.K.H. ; Puk, O. ; Rácz, I. ; Rathkolb, B. ; Rozman, J. ; Schäble, K.-H. ; Schreiner, R. ; Schrewe, A. ; Sina, C. ; Steinkamp, R. ; Thiele, F. ; Willershäuser, M. ; Zeh, R.M. ; Adamski, J. ; Busch, D.H. ; Beckers, J. ; Behrendt, H. ; Daniel, H. ; Esposito, I. ; Favor, J. ; Graw, J. ; Heldmaier, G. ; Höfler, H. ; Ivandic, B. ; Katus, H.A. ; Klingenspor, M. ; Klopstock, T. ; Lengeling, A. ; Mempel, M. ; Müller, W. ; Neschen, S. ; Ollert, M. ; Quintanilla-Martinez, L. ; Rosenstiel, P. ; Schmidt, J. ; Schreiber, S. ; Schughart, K. ; Schulz, S. ; Wolf, E. ; Wurst, W. ; Zimmer, A. ; Hrabě de Angelis, M.
The German Mouse Clinic: A platform for systemic phenotype analysis of mouse models.Warren, M.V. ; Studley, M.L. ; Dubus, P. ; Fiette, L. ; Rozell, B. ; Quintanilla-Martinez, L. ; Raspa, M. ; Breuer, M. ; Song, J.Y. ; Gates, H. ; Brown, S.D. ; Schofield, P.N.
An impending crisis in the provision of histopathology expertise for mouse functional genomics.Reiter, R. ; Gais, P. ; Steuer-Vogt, M.K. ; Boulesteix, A.L. ; Deutschle, T. ; Hampel, R. ; Wagenpfeil, S. ; Rauser, S. ; Walch, A.K. ; Bink, K. ; Jütting, U. ; Neff, F. ; Arnold, W. ; Höfler, H. ; Pickhard, A.
Centrosome abnormalities in head and neck squamous cell carcinoma (HNSCC).Wiech, T. ; Nikolopoulos, E. ; Weis, R. ; Langer, R. ; Bartholomé, K. ; Timmer, J. ; Walch, A.K. ; Höfler, H. ; Werner, M.
Genome-wide analysis of genetic alterations in Barrett's adenocarcinoma using single nucleotide polymorphism arrays.Specht, K. ; Harbeck, N. ; Smida, J. ; Annecke, K. ; Reich, U. ; Naehrig, J. ; Langer, R. ; Mages, J. ; Busch, R. ; Kruse, E. ; Klein-Hitpass, L. ; Schmitt, M. ; Kiechle, M. ; Hoefler, H.
Expression profiling identifies genes that predict recurrence of breast cancer after adjuvant CMF-based chemotherapy.Ejegod, D. ; Sørensen, K.D. ; Moßbrugger, I. ; Quintanilla-Martinez, L. ; Schmidt, J. ; Pedersen, F.S.
Control of pathogenicity and disease specificity of a T-lymphomagenic gammaretrovirus by E-box motifs but not by an overlapping glucocorticoid response element.Henopp, T. ; Anlauf, M. ; Schmitt, A. ; Schlenger, R. ; Zalatnai, A. ; Couvelard, A. ; Ruszniewski, P. ; Schaps, K.P. ; Jonkers, Y.M. ; Speel, E.J. ; Pellegata, N.S. ; Heitz, P.U. ; Komminoth, P. ; Perren, A. ; Klöppel, G.
Glucagon cell adenomatosis: A newly recognized disease of the endocrine pancreas.Markoullis, K. ; Bulian, D. ; Hölzlwimmer, G. ; Quintanilla-Martinez, L. ; Heiliger, K.-J. ; Zitzelsberger, H. ; Scherb, H. ; Mysliwietz, J. ; Uphoff, C.C. ; Drexler, H.G. ; Thure, A. ; Adler, T. ; Busch, D.H. ; Schmidt, J. ; Mahabir, E.
Mycoplasma contamination of murine embryonic stem cells affects cell parameters, germline transmission and chimeric progeny.Mihaljevic, A.L. ; Calzada-Wack, J. ; Hölzlwimmer, G. ; Tost, M. ; Esposito, I.
Histopathological features of autoimmune pancreatitis.Tapio, S. ; Schofield, P.N. ; Adelmann, C. ; Atkinson, M.J. ; Bard, J.L. ; Bijwaard, H. ; Birschwilks, M. ; Dubus, P. ; Fiette, L. ; Gerber, G. ; Gruenberger, M. ; Quintanilla-Martinez, L. ; Rozell, B. ; Saigusa, S. ; Warren, M. ; Watson, C.R. ; Grosche, B.
Progress in updating the European Radiobiology Archives.May, F. ; Matiasek, K. ; Vroemen, M. ; Caspers, C. ; Mrva, T. ; Arndt, C. ; Schlenker, B. ; Gais, P. ; Brill, T. ; Buchner, A. ; Blesch, A. ; Hartung, R. ; Stief, C. ; Gansbacher, B. ; Weidner, N.
GDNF-transduced Schwann cell grafts enhance regeneration of erectile nerves.Riener, M.O. ; Nikolopoulos, E. ; Herr, A. ; Wild, P.J. ; Hausmann, M. ; Wiech, T. ; Orlowska-Volk, M. ; Lassmann, S. ; Walch, A.K. ; Werner, M.
Microarray comparative genomic hybridization analysis of tubular breast carcinoma shows recurrent loss of the CDH13 locus on 16q.Schillinger, U. ; Wexel, G. ; Hacker, C. ; Kullmer, M. ; Koch, C. ; Gerg, M. ; Vogt, S. ; Ueblacker, P. ; Tischer, T. ; Hensler, D. ; Wilisch, J. ; Aigner, J. ; Walch, A.K. ; Stemberger, A. ; Plank, C.
A fibrin glue composition as carrier for nucleic acid vectors.Schmidt, R. ; Bültmann, A. ; Fischel, S. ; Gillitzer, A. ; Cullen, P. ; Walch, A.K. ; Jost, P. ; Ungerer, M. ; Tolley, N.D. ; Lindemann, S. ; Gawaz, M. ; Schömig, A. ; May, A.E.
Extracellular matrix metalloproteinase inducer (CD147) is a novel receptor on platelets, activates platelets, and augments nuclear factor kappaB-dependent inflammation in monocytes.Winkelheide, U. ; Engelhard, K. ; Kaeppel, B. ; Winkler, J. ; Hutzler, P. ; Werner, C. ; Kochs, E.
Cerebral Ischemia and Neurogenesis: A Two-time Comparison.Ying, S. ; Pettengill, M. ; Latham, E.R. ; Walch, A.K. ; Ojcius, D.M. ; Häcker, G.
Premature apoptosis of Chlamydia-infected cells disrupts chlamydial development.Hoffmann, M. ; Rath, E. ; Hoelzlwimmer, G. ; Quintanilla-Martinez, L. ; Loach, D. ; Tannock, G. ; Haller, D.
Lactobacillus reuteri 100-23 transiently activates intestinal epithelial cells of mice that have a complex microbiota during early stages of colonization.Hennig, R. ; Osman, T. ; Esposito, I. ; Giese, N. ; Rao, S.M. ; Ding, X.Z. ; Tong, W.G. ; Büchler, M.W. ; Yokomizo, T. ; Friess, H. ; Adrian, T.E.
BLT2 is expressed in PanINs, IPMNs, pancreatic cancer and stimulates tumour cell proliferation.Klier, M. ; Anastasov, N. ; Hermann, A.C. ; Meindl, T. ; Angermeier, D. ; Raffeld, M. ; Fend, F. ; Quintanilla-Martinez, L.
Specific lentiviral shRNA-mediated knockdown of cyclin D1 in mantle cell lymphoma has minimal effects on cell survival and reveals a regulatory circuit with cyclin D2.Aubele, M. ; Walch, A.K. ; Ludyga, N. ; Braselmann, H. ; Atkinson, M.J. ; Luber, B. ; Auer, G. ; Tapio, S. ; Cooke, T. ; Bartlett, J.M.
Prognostic value of protein tyrosine kinase 6 (PTK6) for long-term survival of breast cancer patients.Rahemtullah, A. ; Longtine, J.A. ; Harris, N.L. ; Dorn, M. ; Zembowicz, A. ; Quintanilla-Fend, L. ; Preffer, F.I. ; Ferry, J.A.
CD20+ T-cell lymphoma: Clinicopathologic analysis of 9 cases and a review of the literature.Wiech, T. ; Nikolopoulos, E. ; Hausmann, M. ; Walch, A.K. ; Werner, M. ; Fisch, P.
A Case of Heterogeneous Breast Cancer with Clonally Expanded T-Cells in the HER2+ and Metastasis of the HER2- Tumor Cells.Esposito, I. ; Kubisova, A. ; Stiehl, A. ; Kulaksiz, H. ; Schirmacher, P.
Secondary sclerosing cholangitis after intensive care unit treatment: Clues to the histopathological differential diagnosis.Esposito, I. ; Born, D. ; Bergmann, F. ; Longerich, T. ; Welsch, T. ; Giese, N.A. ; Büchler, M.W. ; Kleeff, J. ; Friess, H. ; Schirmacher, P.
Autoimmune pancreatocholangitis, non-autoimmune pancreatitis and primary sclerosing cholangitis: A comparative morphological and immunological analysis.Bedke, J. ; Buse, S. ; Esposito, I. ; Schirmacher, P. ; Haferkamp, A. ; Hohenfellner, M.
Evaluation and management of a patient with a bladder mass of uncertain etiology.Salaverria, I. ; Espinet, B. ; Carrió, A. ; Costa, D. ; Astier, L. ; Slotta-Huspenina, J. ; Quintanilla-Martinez, L. ; Fend, F. ; Solé, F. ; Colomer, D. ; Serrano, S. ; Miró, R. ; Beà, S. ; Campo, E.
Multiple recurrent chromosomal breakpoints in mantle cell lymphoma revealed by a combination of molecular cytogenetic techniques.Walch, A.K. ; Rauser, S. ; Deininger, S.O. ; Höfler, H.
MALDI imaging mass spectrometry for direct tissue analysis: A new frontier for molecular histology.Bauer, V.L. ; Braselmann, H. ; Henke, M. ; Mattern, D. ; Walch, A.K. ; Unger, K. ; Baudis, M. ; Lassmann, S. ; Huber, R. ; Wienberg, J. ; Werner, M. ; Zitzelsberger, H.
Chromosomal changes characterize head and neck cancer with poor prognosis.Zischka, H. ; Lichtmannegger, J. ; Jägemann, N. ; Jennen, L. ; Hamöller, D. ; Huber, E. ; Walch, A.K. ; Summer, K.H. ; Göttlicher, M.
Isolation of highly pure rat liver mitochondria with the aid of zone-electrophoresis in a free flow device (ZE-FFE).Zischka, H. ; Larochette, N. ; Hoffmann, F. ; Hamöller, D. ; Jägemann, N. ; Lichtmannegger, J. ; Jennen, L. ; Müller-Höcker, J. ; Roggel, F. ; Göttlicher, M. ; Vollmar, A.M. ; Kroemer, G.
Electrophoretic analysis of the mitochondrial outer membrane rupture induced by permeability transition.Bender, A. ; Beckers, J. ; Schneider, I. ; Hölter, S.M. ; Haack, T.B. ; Ruthsatz, T. ; Vogt Weisenhorn, D.M. ; Becker, L. ; Genius, J. ; Rujescu, D. ; Irmler, M. ; Mijalski, T. ; Mader, M.T. ; Quintanilla-Martinez, L. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Wurst, W. ; Schmid, J. ; Klopstock, T.
Creatine improves health and survival of mice.Langer, R. ; Feith, M. ; Siewert, J.R. ; Wester, H.-J. ; Höfler, H.
Expression and clinical significance of glucose regulated proteins GRP78 (BiP) and GRP94 (GP96) in human adenocarcinomas of the esophagus.Unger, K. ; Malisch, E. ; Thomas, G. ; Braselmann, H. ; Walch, A.K. ; Jackl, G. ; Lewis, P. ; Lengfelder, E. ; Bogdanova, T. ; Wienberg, J. ; Zitzelsberger, H.
Array CGH demonstrates characteristic aberration signatures in human papillary thyroid carcinomas governed by RET/PTC.Hipp, S. ; Walch, A.K. ; Schuster, T. ; Höfler, H. ; Becker, K.-F.
Precise measurement of the E-cadherin repressor Snail in formalin-fixed endometrial carcinoma using protein lysate microarrays.Paschen, S.A. ; Christian, J.G. ; Vier, J. ; Schmidt, F. ; Walch, A.K. ; Ojcius, D.M. ; Häcker, G.
Cytopathicity of Chlamydia is largely reproduced by expression of a single chlamydial protease.Kremer, M. ; Horn, T. ; Koch, I. ; Dechow, T. ; Gattenloehner, S. ; Pfeiffer, W. ; Quintanilla-Martinez, L. ; Fend, F.
Quantitation of the JAK2V617F mutation in microdissected bone marrow trephines: Equal mutational load in myeloid lineages and rare involvement of lymphoid cells.Miederer, M. ; Henriksen, G. ; Alke, A. ; Mossbrugger, I. ; Quintanilla-Martinez, L. ; Senekowitsch-Schmidtke, R. ; Essler, M.
Preclinical evaluation of the alpha-particle generator nuclide 225Ac for somatostatin receptor radiotherapy of neuroendocrine tumors.Hömig-Hölzel, C. ; Hojer, C. ; Rastelli, J. ; Casola, S. ; Strobl, L.J. ; Müller, W. ; Quintanilla-Martinez, L. ; Gewies, A. ; Ruland, J. ; Rajewsky, K. ; Zimber-Strobl, U.
Constitutive CD40 signaling in B cells selectively activates the noncanonical NF-kappaB pathway and promotes lymphomagenesis.Hense, B.A. ; Gais, P. ; Jütting, U. ; Scherb, H. ; Rodenacker, K.
Use of fluorescence information for automated phytoplankton investigation by image analysis.Fend, F. ; Tzankov, A. ; Bink, C. ; Seidl, S. ; Quintanilla-Martinez, L. ; Kremer, M. ; Dirnhofer, S.
Modern techniques for the diagnostic evaluation of the trephine bone marrow biopsy: Methodological aspects and applications.Matiasek, K. ; Gais, P. ; Rodenacker, K. ; Jütting, U. ; Tanck, J.J. ; Schmahl, W.
Stereological characteristics of the equine accessory nerve.Walch, A.K. ; Seidl, S. ; Hermannstädter, C. ; Rauser, S. ; Deplazes, J. ; Langer, R. ; von, Weyhern, C.H. ; Sarbia, M. ; Busch, R. ; Feith, M. ; Gillen, S. ; Höfler, H. ; Luber, B.
Combined analysis of Rac1, IQGAP1, Tiam1 and E-cadherin expression in gastric cancer.Villmann, T. ; Schleif, F.M. ; Kostrzewa, M. ; Walch, A.K. ; Hammer, B.
Classification of mass-spectrometric data in clinical proteomics using learning vector quantization methods.Blechschmidt, K. ; Sassen, S. ; Schmalfeldt, B. ; Schuster, T. ; Höfler, H. ; Becker, K.F.
The E-cadherin repressor Snail is associated with lower overall survival of ovarian cancer patients.Petropoulos, K. ; Arseni, N. ; Schessl, C. ; Stadler, C.R. ; Rawat, V.P.S. ; Deshpande, A.J. ; Heilmeier, B. ; Hiddemann, W. ; Quintanilla-Martinez, L. ; Bohlander, S.K. ; Feuring-Buske, M. ; Buske, C.
A novel role for Lef-1, a central transcription mediator of Wnt signaling, in leukemogenesis.Bremm, A. ; Walch, A.K. ; Fuchs, M. ; Mages, J. ; Duyster, J. ; Keller, G. ; Hermannstädter, C. ; Becker, K.F. ; Rauser, S. ; Langer, R. ; von, Weyhern, C.H. ; Höfler, H. ; Luber, B.
Enhanced activation of epidermal growth factor receptor caused by tumor-derived E-cadherin mutations.Bink, K. ; Haralambieva, E. ; Kremer, M. ; Ott, G. ; Beham-Schmid, C. ; de, Leval, L. ; Peh, S.C. ; Laeng, H.R. ; Jütting, U. ; Hutzler, P. ; Quintanilla-Martinez, L. ; Fend, F.
Primary extramedullary plasmacytoma: Similarities with and differences from multiple myeloma revealed by interphase cytogenetics.Lisse, T.S. ; Thiele, F. ; Fuchs, H. ; Hans, W. ; Przemeck, G.K.H. ; Abe, K. ; Rathkolb, B. ; Quintanilla-Martinez, L. ; Hölzlwimmer, G. ; Helfrich, M. ; Wolf, E. ; Ralston, S.H. ; Hrabě de Angelis, M.
ER stress-mediated apoptosis in a new mouse model of Osteogenesis imperfecta.Herens, C. ; Lambert, F. ; Quintanilla-Martinez, L. ; Bisig, B. ; Deusings, C. ; de Leval, L.
Cyclin D1-negative mantle cell lymphoma with cryptic t(12;14)(p13;q32) and cyclin D2 overexpression.Fuchs, M. ; Hermannstädter, C. ; Hutzler, P. ; Häcker, G. ; Haller, F. ; Höfler, H. ; Luber, B.
Deletion of exon 8 increases cisplatin-induced E-cadherin cleavage.Slotta-Huspenina, J. ; Koch, I. ; Richter, M. ; Bink, K. ; Kremer, M. ; Specht, K. ; Krugmann, J. ; Quintanilla-Martinez, L. ; Fend, F.
Cyclin D1 positive multiple myeloma: Predominance of the short, 3'UTR-deficient transcript is associated with high cyclin D1 mRNA levels in cases with t(11;14) translocation, but does not correlate with proliferation rate or genomic deletions.Rawat, V.P.S. ; Thoene, S. ; Naidu, V.M. ; Arseni, N. ; Heilmeier, B. ; Metzeler, K. ; Petropoulos, K. ; Deshpande, A.J. ; Quintanilla-Martinez, L. ; Bohlander, S.K. ; Spiekermann, K. ; Hiddemann, W. ; Feuring-Buske, M. ; Buske, C.
Overexpression of CDX2 perturbs HOX gene expression in murine progenitors depending on its N-terminal domain and is closely correlated with deregulated HOX gene expression in human acute myeloid leukemia.Becker, K.-F. ; Schott, C. ; Hipp, S. ; Metzger, V. ; Porschewski, P. ; Beck, R. ; Nährig, J. ; Becker, I. ; Höfler, H.
Quantitative protein analysis from formalin-fixed tissues: Implications for translational clinical research and nanoscale molecular diagnosis.Mossbrugger, I. ; Hoelzlwimmer, G. ; Calzada-Wack, J. ; Quintanilla-Martinez, L.
Standardized morphological phenotyping of mouse models of human diseases within the German Mouse Clinic.Blechschmidt, K. ; Kremmer, E. ; Hollweck, R. ; Mylonas, I. ; Höfler, H. ; Kremer, M. ; Becker, K.F.
The E-cadherin repressor snail plays a role in tumor progression of endometrioid adenocarcinomas.Keim, M.
Das Patched1-Gen und seine Beteiligung an der Entwicklung des ZNS.Enard, W. ; Hammerschmidt, K. ; Brückner, M.K. ; Giger, T. ; Gehre, S. ; Hölter, S.M. ; Becker, L. ; Groszer, M. ; Wiebe, V. ; Nickel, B. ; Müller, U. ; Adler, T. ; Bolle, I. ; Busch, D.H. ; Calzada-Wack, J. ; Dalke, C. ; Ehrhardt, N. ; Favor, J. ; Fuchs, H. ; Gailus-Durner, V. ; Hans, W. ; Hölzlwimmer, G. ; Javaheri, A. ; Kling, E. ; Kunder, S. ; Moßbrugger, I. ; Rácz, I. ; Rathkolb, B. ; Rozman, J. ; Schrewe, A. ; Graw, J. ; Hrabě de Angelis, M. ; Ivandic, B. ; Kalaydjiev, S. ; Klingenspor, M. ; Klopstock, T. ; Ollert, M. ; Quintanilla-Martinez, L. ; Schulz, H. ; Wolf, E. ; Wurst, W. ; Zimmer, A. ; Fisher, S.E. ; Arendt, T. ; Fischer, J. ; Schwarz, J. ; Pääbo, S.
A mouse model for human-specific changes in FOXP2, a gene important for speech and language.Fuchs, H. ; Gailus-Durner, V. ; Abe, K. ; Becker, L. ; Bolle, I. ; Calzada-Wack, J. ; Ehrhardt, N. ; Dalke, C. ; Hans, W, ; Hölter, S.M. ; Hölzlwimmer, G. ; Horsch, M. ; Javaheri, A. ; Aguilar, A. ; Kalaydjiev, S. ; Adler, T. ; Kallnik, M. ; Kling, E. ; Kunder, S. ; Lengger, C. ; Lisse, T.S. ; Maier, H. ; Mörth, C. ; Mossbrugger, I. ; Naton, B. ; Prehn, C. ; Rácz, I. ; Rathkolb, B. ; Rozman, J. ; Schrewe, A. ; Steinkamp, R. ; Thiele, F. ; Adamski, J. ; Beckers, J. ; Behrendt, H. ; Busch, D.H. ; Favor, J. ; Graw, J. ; Heldmaier, G. ; Höfler, H. ; Ivandic, B. ; Jakob, T. ; Katus, H.A. ; Klingenspor, M. ; Klopstock, T. ; Lengeling, A. ; Müller, W. ; Ollert, M. ; Quintanilla-Martinez, L. ; Schulz, H. ; Wolf, E. ; Wurst, W. ; Zimmer, A. ; Hrabě de Angelis, M.
Systemic analysis of mouse mutants at the German Mouse Clinic.Becker, K.-F. ; Rosivatz, E. ; Blechschmidt, K. ; Kremmer, E. ; Sarbia, M. ; Höfler, H.
Analysis of the E-cadherin repressor Snail in primary human cancers.Rupp, A. ; Dornseifer, U. ; Fischer, A. ; Schmahl, W. ; Rodenacker, K. ; Jütting, U. ; Gais, P. ; Biemer, E. ; Papadopulos, N. ; Matiasek, K.
Electrophysiologic assessment of sciatic nerve regeneration in the rat: Surrounding limb muscles feature strongly in recordings from the gastrocnemius muscle.Aichler, M. ; Algül, H. ; Behne, D. ; Hölzlwimmer, G. ; Michalke, B. ; Quintanilla-Martinez, L. ; Schmidt, J. ; Schmid, R.M. ; Brielmeier, M.
Selenium status alters tumour differentiation but not incidence or latency of pancreatic adenocarcinomas in Ela-TGF-alpha p53+/ mice.Rupp, A. ; Dornseifer, U. ; Rodenacker, K. ; Fichter, A. ; Jütting, U. ; Gais, P. ; Papadopulos, N. ; Matiasek, K.
Temporal progression and extent of the return of sensation in the foot provided by the saphenous nerve after sciatic nerve transection and repair in the rat - implications for nociceptive assessments.Yoon, H. ; He, H. ; Nagy, R. ; Davuluri, R. ; Suster, S. ; Schoenberg, D. ; Pellegata, N.S. ; de la Chapelle, A.
Identification of a novel noncoding RNA gene, NAMA, that is downregulated in papillary thyroid carcinoma with BRAF mutation and associated with growth arrest.Mao, Z. ; Quintanilla-Martinez, L. ; Raffeld, M. ; Richter, M. ; Krugmann, J. ; Burek, C. ; Hartmann, E. ; Rudiger, T. ; Jaffe, E.S. ; Müller-Hermelink, H.K. ; Ott, G. ; Fend, F. ; Rosenwald, A.
IgVH mutational status and clonality analysis of Richter's transformation: Diffuse large B-cell lymphoma and Hodgkin lymphoma in association with B-cell chronic lymphocytic leukemia (B-CLL) represent 2 different pathways of disease evolution.Ruiz, P.A. ; Braune, A. ; Hölzlwimmer, G. ; Quintanilla-Fend, L. ; Haller, D.
Quercetin inhibits TNF-induced NF-kappaB transcription factor recruitment to proinflammatory gene promoters in murine intestinal epithelial cells.Rauser, S. ; Weis, R. ; Braselmann, H. ; Feith, M. ; Stein, H.J. ; Langer, R. ; Hutzler, P. ; Hausmann, M. ; Lassmann, S. ; Siewert, J.R. ; Höfler, H. ; Werner, M. ; Walch, A.K.
Significance of HER2 low-level copy gain in Barrett's cancer: Implications for fluorescence in situ hybridization testing in tissues.Lassmann, S. ; Shen, Y. ; Jütting, U. ; Wiehle, P. ; Walch, A.K. ; Gitsch, G. ; Hasenburg, A. ; Werner, M.
Predictive value of aurora-A/STK15 expression for late stage epithelial ovarian cancer patients treated by adjuvant chemotherapy.Kaiser-Schulz, G. ; Heit, A. ; Quintanilla-Martinez, L. ; Hammerschmidt, F. ; Hess, S. ; Jennen, L. ; Rezaei, H. ; Wagner, H. ; Schatzl, H.M.
Polylactide-Coglycolide Microspheres CoEncapsulating Recombinant Tandem Prion Protein with CpG-Oligonucleotide Break Self-Tolerance to Prion Protein in Wild-Type Mice and Induce CD4 and CD8 T Cell Responses.Napieralski, R. ; Ott, K. ; Kremer, M. ; Becker, K. ; Boulesteix, A.-L. ; Lordick, F. ; Siewert, J.R. ; Höfler, H. ; Keller, G.
Methylation of tumor-related genes in neoadjuvant-treated gastric cancer: Relation to therapy response and clinicopathologic and molecular features.Langer, R. ; Specht, K. ; Becker, K. ; Ewald, P. ; Ott, K. ; Lordick, F. ; Siewert, J.R. ; Höfler, H.
Comparison of pretherapeutic and posttherapeutic expression levels of chemotherapy-associated genes in adenocarcinomas of the esophagus treated by 5-fluorouracil- and cisplatin-based neoadjuvant chemotherapy.Lassmann, S. ; Schuster, I. ; Walch, A.K. ; Göbel, H. ; Jütting, U. ; Makowiec, F. ; Hopt, U. ; Werner, M.
STAT3 mRNA and protein expression in colorectal cancer: Effects on STAT3-inducible targets linked to cell survival and proliferation.Soerensen, A.B. ; Lund, A.H. ; Kunder, S. ; Quintanilla-Martinez, L. ; Schmidt, J. ; Wang, B. ; Wabl, M. ; Pedersen, F.S.
Impairment of alternative splice sites defining a novel gammaretroviral exon within gag modifies the oncogenic properties of Akv murine leukemia virus.Ferch, U. ; Meyer zum Büschenfelde, C. ; Gewies, A. ; Wegener, E. ; Rauser, S. ; Peschel, C. ; Krappmann, D. ; Ruland, J.
MALT1 directs B cell receptor–induced canonical nuclear factor-kappaB signaling selectively to the c-Rel subunit.Pellegata, N.S. ; Quintanilla-Martinez, L. ; Keller, G. ; Liyanarachchi, S. ; Höfler, H. ; Atkinson, M.J. ; Fend, F.
Human pheochromocytomas show reduced p27Kip1 expression that is not associated with somatic gene mutations and rarely with deletions.Tirard, M. ; Almeida, O.F.X. ; Hutzler, P. ; Melchior, F. ; Michaelidis, T.M.
Sumoylation and proteasomal activity determine the transactivation properties of the mineralocorticoid receptor.Sorensen, K.D. ; Kunder, S. ; Quintanilla-Martinez, L. ; Sorensen, J. ; Schmidt, J. ; Pedersen, F.S.
Enhancer mutations of Akv murine leukemia virus inhibit the induction of mature B-cell lymphomas and shift disease specificity towards the more differentiated plasma cell stage.Gamboa-Dominguez, A. ; Seidl, S. ; Reyes-Gutierrez, E. ; Hermannstädter, C. ; Quintanilla-Martinez, L. ; Busch, R. ; Höfler, H. ; Fend, F. ; Luber, B.
Prognostic significance of p21WAF1/CIP1, p27Kip1, p53 and E-cadherin expression in gastric cancer.Kunder, S. ; Calzada-Wack, J. ; Hölzlwimmer, G. ; Müller, J. ; Kloss, C. ; Howat, W. ; Schmidt, J. ; Höfler, H. ; Warren, M. ; Quintanilla-Martinez, L.
Comprehensive Antibody Panel for Immunohistochemical Analysis of Formalin-Fixed, Paraffin-Embedded Hematopoietic Neoplasms of Mice: Analysis of Mouse Specific and Human Antibodies Cross-Reactive with Murine Tissue.Engelhard, K. ; Winkelheide, U. ; Werner, C. ; Kluge, J. ; Eberspächer, E. ; Hollweck, R. ; Hutzler, P. ; Winkler, J. ; Kochs, E.
Sevoflurane affects neurogenesis after forebrain ischemia in rats.Aubele, M. ; Auer, G. ; Walch, A.K. ; Munro, A. ; Atkinson, M.J. ; Braselmann, H. ; Fornander, T. ; Bartlett, J.M.S.
PTK (protein tyrosine kinase)-6 and HER2 and 4, but not HER1 and 3 predict long-term survival in breast carcinomas.Favor, J. ; Gloeckner, C.J. ; Janik, D. ; Klempt, M. ; Neuhäuser-Klaus, A. ; Pretsch, W. ; Schmahl, W. ; Quintanilla-Fend, L.
Type IV procollagen missense mutations associated with defects of the eye, vascular stability, the brain, kidney function and embryonic or postnatal viability in the mouse, Mus musculus: An extension of the Col₄a₁allelic series and the identification of the first twoCol₄a₂ mutant alleles.Kunder, S.K.L.
Histologische, immunhistochemische und molekularbiologische Charakterisierung retrovirusinduzierter, muriner hämatopoietischer Neoplasien.Hahn, U.K. ; Aichler, M. ; Boehm, R. ; Beyer, W.
Comparison of the immunological memory after DNA vaccination and protein vaccination against anthrax in sheep.Schäffer, E.H. ; Marquart, K.-H. ; Brandes, K. ; Kunder, S. ; Jennen, L.
Okulare Onchozerkose bei einem Hund.Deshpande, A.J. ; Cusan, M. ; Rawat, V.P.S. ; Reuter, H. ; Krause, A. ; Pott, C. ; Quintanilla-Martinez, L. ; Kakadia, P. ; Kuchenbauer, F. ; Ahmed, F. ; Delabesse, E. ; Hahn, M. ; Lichtner, P. ; Kneba, M. ; Hiddemann, W. ; Macintyre, E. ; Mecucci, C. ; Ludwig, W.D. ; Humphries, R.K. ; Bohlander, S.K. ; Feuring-Buske, M. ; Buske, C.
Acute myeloid leukemia is propagated by a leukemic stem cell with lymphoid characteristics in a mouse model of CALM/AF10-positive leukemia.Gantner, S. ; Schmid, M. ; Dürr, C. ; Schuhegger, R. ; Steidle, A. ; Hutzler, P. ; Langebartels, C. ; Eberl, L. ; Hartmann, A. ; Dazzo, F.B.
In situ quantification of the spatial scale of calling distances and population density-independent N-acylhomoserine lactone-mediated communication by rhizobacteria colonized on plant roots.Unger, K. ; Zurnadzhy, L. ; Walch, A.K. ; Mall, M. ; Bogdanova, T. ; Braselmann, H. ; Hieber, L. ; Tronko, N. ; Hutzler, P. ; Jeremiah, S. ; Thomas, G.
RET rearrangements in post-Chernobyl papillary thyroid carcinomas with a short latency analysed by interphase FISH.Pellegata, N.S. ; Quintanilla-Martinez, L. ; Siggelkow, H. ; Samson, E. ; Bink, K. ; Höfler, H. ; Fend, F. ; Graw, J. ; Atkinson, M.J.
Germ-line mutations in p27Kip1 cause a multiple endocrine neoplasia syndrome in rats and humans.Ma, S.L. ; Sorensen, A.B. ; Kunder, S.K.L. ; Sorensen, K.D. ; Quintanilla-Martinez, L. ; Morris, D.W. ; Schmidt, J. ; Pedersen, F.S.
The Icsbp locus is a common proviral insertion site in mature B-cell lymphomas/plasmacytomas induced by exogenous murine leukemia virus.Koch, I. ; Slotta-Huspenina, J. ; Hollweck, R. ; Anastasov, N. ; Höfler, H. ; Quintanilla-Martinez, L. ; Fend, F.
Real-time quantitative RT-PCR shows variable, assay-dependent sensitivity to formalin fixation: Implications for direct comparison of transcript levels in paraffin-embedded tissues.Kremer, M. ; Horn,T. ; Dechow, T. ; Tzankov, A. ; Quintanilla-Martinez, L. ; Fend, F.
The JAK2 V617F mutation occurs frequently in myelodysplastic/myeloproliferative diseases, but is absent in true myelodysplastic syndromes with fibrosis.Pape, M. ; Engelhard, K. ; Eberspächer, E. ; Hollweck, R. ; Kellermann, K. ; Zintner, S. ; Hutzler, P. ; Werner, C.
The long-term effect of sevoflurane on neuronal cell damage and expression of apoptotic factors after cerebral ischemia and reperfusion in rats.Quintanilla-Martinez, L. ; Pittaluga, S. ; Miething, C. ; Klier, M. ; Rudelius, M. ; Davies-Hill, T. ; Anastasov, N. ; Martinez, A. ; Vivero, A. ; Duyster, J. ; Jaffe, E.S. ; Fend, F. ; Raffeld, M.
NPM-ALK-dependent expression of the transcription factor CCAAT/enhancer binding protein beta in ALK-positive anaplastic large cell lymphoma.Yu, P. ; Wellmann, U. ; Kunder, S. ; Quintanilla-Martinez, L. ; Jennen, L. ; Dear, N. ; Amann, K. ; Bauer, S. ; Winkler, T.H. ; Wagner, H.
Toll-like receptor 9-independent aggraviation of glomerulonnephritis in a novel model of SLE.Rudelius, M. ; Pittaluga, S. ; Nishizuka, S. ; Pham, T.H.-T. ; Fend, F. ; Jaffe, E.S. ; Quintanilla-Martinez, L. ; Raffeld, M.
Constitutive activation of Akt contributes to the pathogenesis and survival of mantle cell lymphoma.Reiter, R. ; Gais, P. ; Jütting, U. ; Steuer-Vogt, M.K. ; Pickhard, A. ; Bink, K. ; Rauser, S. ; Lassmann, S. ; Höfler, H. ; Werner, M. ; Walch, A.K.
Aurora kinase A messenger RNA overexpression is correlated with tumor progression and shortened survival in head and neck squamous cell carcinoma.Kobrin, C. ; Cha, S.-C. ; Qin, H. ; Raffeld, M. ; Fend, F. ; Quintanilla-Martinez, L. ; Grove, S. ; Jaffe, E.S. ; Kwak, L.W.
Molecular analysis of light-chain switch and acute lymphoblastic leukemia transformation in two follicular lymphomas: Implications for lymphomagenesis.Rodenacker, K. ; Hense, B.A. ; Jütting, U. ; Gais, P.
Automatic analysis of aqueous specimens for phytoplankton structure recognition and population estimation.Takenaka, S. ; Karg, E.W. ; Kreyling, W.G. ; Lentner, B. ; Möller, W. ; Behnke-Semmler, M. ; Jennen, L. ; Walch, A.K. ; Michalke, B. ; Schramel, P. ; Heyder, J.
Distribution pattern of inhaled ultrafine gold particles in the rat lung.Rosivatz, E. ; Becker, K.-F. ; Kremmer, E. ; Schott, C. ; Blechschmidt, K. ; Höfler, H. ; Sarbia, M.
Expression and nuclear localization of Snail, an E-cadherin repressor, in adenocarcinomas of the upper gastrointestinal tract.Horn, T. ; Kremer, M. ; Dechow, T. ; Pfeifer, W.M. ; Geist, B. ; Perker, M. ; Duyster, J. ; Quintanilla-Martinez, L. ; Fend, F.
Detection of the activating JAK2 V617F mutation in paraffin-embedded trephine bone marrow biopsies of patients with chronic myeloproliferative diseases.Pazzaglia, S. ; Tanori, M. ; Mancuso, M. ; Rebessi, S. ; Leonardi, S. ; di Majo, V. ; Covelli, V. ; Atkinson, M.J. ; Hahn, H. ; Saran, A.
Linking DNA damage to medulloblastoma tumorigenesis in patched heterozygous knockout mice.Rosemann, M. ; Kuosaite, V. ; Kremer, M. ; Favor, J. ; Quintanilla-Martinez, L. ; Atkinson, M.J.
Multilocus inheritance determines predisposition to alpha-radiation induced bone tumourigenesis in mice.Petrich, T. ; Quintanilla-Martinez, L. ; Korkmaz, Z. ; Samson, E. ; Helmeke, H.-J. ; Meyer, G.J. ; Knapp, W.H. ; Pötter, E.
Effective cancer therapy with the alpha-particle ermitter [211At]astatine in a mouse model of genetically modified sodium/iodide symporter-expressing tumors.Gerlach, U. ; Kayser, G. ; Walch, A.K. ; Hopt, U. ; Schulte-Mönting, J. ; Werner, M. ; Lassmann, S.
Centrosome-, chromosomal-passenger- and cell-cycle-associated mRNAs are differentially regulated in the development of sporadic colorectal cancer.Schuhegger, R. ; Ihring, A. ; Gantner, S. ; Bahnweg, G. ; Knappe, C. ; Vogg, G. ; Hutzler, P. ; Schmid, M. ; van Breusegem, F. ; Eberl, L. ; Hartmann, A.
Induction of systemic resistance in tomato by N-acyl-L-homoserine lactone-producing rhizosphere bacteria.Peters, D.D. ; Marschall, S. ; Mahabir, E. ; Boersma, A. ; Heinzmann, U. ; Schmidt, J. ; Hrabě de Angelis, M.
Risk assessment of mouse hepatitis virus infection via in vitro fertilization and embryo transfer by the use of zona-intact and laser-microdissected oocytes.Jörg, A. ; Grubert, T. ; Grimm, T. ; Guenzi, E. ; Naschberger, E. ; Samson, E. ; Oostendorp, R. ; Keller, U. ; Stürzl, M.
Maternal HIV type 1 infection suppresses MMP-1 expression in endothelial cells of uninfected newborns: Nonviral vertical transmission of HIV type 1-related effects.Roselli, F. ; Tirard, M. ; Lu, J. ; Hutzler, P. ; Lamberti, P. ; Livrea, P. ; Morabito, M. ; Almeida, O.F.X.
Soluble ß-amyloid1-40 induces NMDA-dependent degradation of postsynaptic density-95 at glutamatergic synapses.Kremer, M. ; Ott, G. ; Nathrath, M. ; Specht, K. ; Stecker, K. ; Alexiou, Ch. ; Quintanilla-Martinez, L. ; Fend, F.
Primary extramedullary plasmacytoma and multiple myeloma: Phenotypic differences revealed by immunohistochemical analysis.Fend, F. ; Bock, O. ; Kremer, M. ; Specht, K. ; Quintanilla-Martinez, L.
Ancillary techniques in bone marrow pathology: Molecular diagnostic on bone marrow trephine biopsies.Kremer, M. ; Quintanilla-Martinez, L. ; Nährig, J. ; Schilling, Ch. von ; Fend, F.
Immunohistochemistry in bone marrow pathology: A useful adjunct for morphologic diagnosis.Wiech, T. ; Walch, A.K. ; Werner, M.
Histopathological Classification of Nonneoplastic and Neoplastic Gastrointestinal Submucosal Lesions.Klymenko, S.V. ; Bink, K. ; Trott, K.-R. ; Bebeshko, V.G. ; Bazyka, D.A. ; Dmytrenko, I.V. ; Abramenko, I.V. ; Bilous, N.I. ; Zitzelsberger, H. ; Misurin, A.V. ; Atkinson, M.J. ; Rosemann, M.
MLL gene alterations in radiation-associated acute myeloid leukemia.Klymenko, S. ; Trott, K. ; Atkinson, M.J. ; Bink, K. ; Bebeshko, V. ; Bazyko, D. ; Dmytrenko, I. ; Abramenko, I. ; Bilous, N. ; Misurin, A. ; Zitzelsberger, H.
Aml1 gene rearrangements and mutations in radiation-associated acute myeloid leukemia and myelodysplastic syndromes.Bertaux, J. ; Schmid, M. ; Hutzler, P. ; Hartmann, A. ; Garbaye, J. ; Frey-Klett, P.
Occurrence and distribution of endobacteria in the plant-associated mycelium of the ectomycorrhizal fungus Laccaria bicolor S238N.Schäffer, E.H. ; Quintanilla-Martinez, L. ; Marquart, K.-H. ; Kunder, S. ; Scheel, C. ; Jennen, L.
Perikardiales malignes Mesotheliom beim Beagle: Fallbericht mit immunohistochemischen und elektronenmikroskopischen Befunden.Eumorphia Consortium (Brown, S.D.M. ; Chambon, P. ; Hrabě de Angelis, M. ; Wurst, W. ; Abe, K. ; Beckers, J. ; Busch, D.H. ; Dalke, C. ; Gailus-Durner, V. ; Elvert, R. ; Franz, T. ; Fuchs, H. ; Graw, J. ; Hölter, S.M. ; Jakob, T. ; Kalaydjiev, S. ; Kallnik, M. ; Klempt, M. ; Klingenspor, M. ; Klopstock, T. ; Lengger, C. ; Quintanilla-Martinez, L. ; Pedersen, V. ; Puk, O. ; Schneider, I. ; Vogt Weisenhorn, D.M. ; Wagner, S. ; Wolf, E.)
EMPReSS: Standardized phenotype screens for functional annotation of the mouse genome.Gailus-Durner, V. ; Fuchs, H. ; Becker, L. ; Bolle, I. ; Brielmeier, M. ; Calzada-Wack, J. ; Evert, R. ; Ehrhardt, N. ; Dalke, C. ; Franz, T.J. ; Grundner-Culemann, E. ; Hammelbacher, S. ; Hölter, S.M. ; Hoeltzlwimmer, G. ; Horsch, M. ; Javaheri, A. ; Kataydjiev, S.V. ; Klempt, M. ; Kling, E. ; Kunder, S. ; Lengger, C. ; Lisse, T.S. ; Mijalski, T. ; Naton, B. ; Pedersen, V. ; Prehn, C. ; Przemeck, G.K.H. ; Rácz, I. ; Reinhard, C. ; Reitmeir, P. ; Schneider, I. ; Schrewe, A. ; Steinkamp, R. ; Zybill, C. ; Adamski, J. ; Beckers, J. ; Behrendt, H. ; Favor, J. ; Graw, J. ; Heldmaier, G. ; Höfler, H. ; Ivandic, B. ; Katus, H.A. ; Kirchhof, P. ; Kiingenspor, M. ; Kopstock, T. ; Lengeling, A. ; Mfitier, W. ; Ohl, F. ; Ollert, M. ; Quintanilla-Martinez, L. ; Schmidt, J. ; Schulz, S. ; Wolf, E. ; Wurst, W. ; Zimmer, A. ; Busch, D.H. ; Hrabě de Angelis, M.
Introducing the German Mouse Clinic: Open access platform for standardized phenotyping.Möbius, C. ; Stein, H.J. ; Spieß, C. ; Becker, I. ; Feith, M. ; Theisen, J. ; Gais, P. ; Jütting, U. ; Siewert, J.R.
COX2 expression, angiogenesis, proliferation and survival in Barrett's cancer.Treml, B.S. ; Winderl, S. ; Radykewicz, R. ; Herz, M. ; Schweizer, G. ; Hutzler, P. ; Glawischnig, E. ; Ruiz, R.A.T.
The gene ENHANCER OF PINOID controls cotyledon development in the Arabidopsis embryo.Kayser, G. ; Gerlach, U. ; Walch, A.K. ; Nitschke, R. ; Haxelmans, S. ; Kayser, K. ; Hopt, R. ; Werner, M. ; Lassmann, S.
Numerical and structural centrosome aberrations are on early and stable event in the adenoma-carcinoma sequence of colorectal carcinomas.Wittmaack, K. ; Wehnes, H. ; Heinzmann, U. ; Agerer, R.
An overview on bioaerosols viewed by scanning electron microscopy.Beck, V. ; Herold, H. ; Benge, A. ; Luber, B. ; Hutzler, P. ; Tschesche, H. ; Kessler, H. ; Schmitt, M. ; Geppert, H.-D. ; Reuning, U.
ADAM15 decreases integrin alphavß3/vitronectin-mediated ovarian cancer cell adhesion and motility in an RGD-dependent fashion.Atkinson, M.J. ; Spanner, M.T. ; Rosemann, M. ; Linzner, U. ; Müller, W.A. ; Gössner, W.
Intracellular sequestration of 223Ra by the iron-storage protein ferritin.Fuchs, M. ; Hermannstädter, C. ; Specht, K. ; Knyazev, P. ; Ullrich, A. ; Rosivatz, E. ; Busch, R. ; Hutzler, P. ; Höfler, H. ; Luber, B.
Effect of tumor-associated mutant E-cadherin variants with defects in exons 8 or 9 on matrix metalloproteinase 3.Schessl, C. ; Rawat, V.P.S. ; Cusan, M. ; Deshpande, A. ; Kohl, T.M. ; Spiekermann, K. ; Hiddemann, W. ; Quintanilla-Martinez, L. ; Bohlander, S.K. ; Feuring-Buske, M. ; Buske, C.
The AML1-ETO fusion gene and the FLT3 lenght mutation collaborate in inducing acute leukemia in mice.Wahl, M.B. ; Heinzmann, U. ; Imai, K.
LongSAGE analysis significantly improves genome annotation: identifications of novel genes and alternative transcripts in the mouse.Gamboa-Dominguez, A. ; Quintanilla-Martinez, L. ; Becker, K.-F. ; Höfler, H.
E-cadherin expression in sporadic gastric cancer from Mexico: Exon 8 and 9 deletions are infrequent events associated with poor survival.Wahl, M.B. ; Heinzmann, U. ; Imai, K.
LongSAGE analysis revealed the presence of a large number of novel antisense genes in the mouse genome.Sørensen, K.D. ; Sørensen, A.B. ; Quintanilla-Martinez, L. ; Kunder, S. ; Schmidt, J. ; Pedersen, F.S.
Distinct roles of enhancer nuclear factor 1 (NF1) sites in plasmacytoma and osteopetrosis induction by Akv1-99 murine leukemia virus.Rodriguez, N. ; Fend, F. ; Jennen, L. ; Schiemann, M. ; Wantia, N. ; Prazeres da Costa, C.U. ; Dürr, S. ; Heinzmann, U. ; Wagner, H. ; Miethke, T.
Polymorphonuclear neutrophils improve replication of Chlamydia pneumoniae in vivo upon MyD88-dependent attraction.Heidenreich, W.F. ; Müller, W.A. ; Paretzke, H.G. ; Rosemann, M.
Bone cancer risk in mice exposed to 224Ra: Protraction effects from promotion.Seidl, C. ; Schröck, H. ; Seidenschwang, S. ; Beck, R. ; Schmid, E. ; Abend, M. ; Becker, K.-F. ; Apostolidis, C. ; Nikula, T.K. ; Kremmer, E. ; Schwaiger, M.
Cell death triggered by alpha-emitting 213Bi-immunoconjugates in HSC45-M2 gastric cancer cells is different from apoptotic cell death.Yu, P. ; Constien, R. ; Dear, N. ; Katan, M. ; Hanke, P. ; Bunney, T.D. ; Kunder, S. ; Quintanilla-Martinez, L. ; Huffstadt, U. ; Schröder, A. ; Jones, N.P. ; Peters, T. ; Fuchs, H. ; Hrabě de Angelis, M. ; Nehls, M. ; Grosse, J. ; Wabnitz, P. ; Meyer, T.P.H. ; Yasuda, K. ; Schiemann, M. ; Schneider-Fresenius, C. ; Jagla, W. ; Russ, A. ; Popp, A. ; Josephs, M. ; Marquardt, A. ; Laufs, J. ; Schmittwolf, C. ; Wagner, H. ; Pfeffer, K. ; Mudde, G.C.
Autoimmunity and inflammation due to a gain-of-function mutation in phospholipase Cgamma2 that specifically increases external Ca2+ entry.Born, M. ; Quintanilla-Fend, L. ; Braselmann, H. ; Reich, U. ; Richter, M. ; Hutzler, P. ; Aubele, M.
Simultaneous over-expression of the Her2/neu and PTK6 tyrosine kinases in archival invasive ductal breast carcinomas.Hieber, E.
Sekundär - Intraokulare (Metastatische) Tumoren der Uvea : Anamnestische und ophthalmopathologische Untersuchung von 31 Fällen bei Hund, Katze und Kaninchen.Daldrup-Link, H.E. ; Rudelius, M. ; Metz, S. ; Piontek, G. ; Pichler, B. ; Settles, M. ; Heinzmann, U. ; Schlegel, J. ; Oostendorp, R.A.J. ; Rummeny, E.J.
Cell tracking with gadophrin-2: A biofunctional contrast agent for MR imaging, optical imaging and fluorescence microscopy.Paffenholz, R. ; Heinzmann, U.
Vestibular defects in head-tilt mice result from mutations in Nox3, encoding an NADPH oxidase.Schofield, P.N. ; Goessner, W. ; Höfler, H. ; Quintanilla-Martinez, L.
Pathbase: A new reference resource and database for laboratory mouse pathology.Wahl, M. ; Shukunami, C. ; Heinzmann, U. ; Hamajima, K. ; Hiraki, Y. ; Imai, K.
Transcriptome analysis of early chondrogenesis in ATDC5 cells induced by bone morphogenetic protein 4.Panhuysen, M. ; Vogt Weisenhorn, D.M. ; Blanquet, V. ; Brodski, C. ; Heinzmann, U. ; Beisker, W. ; Wurst, W.
Effects of Wnt1 signaling on proliferation in the developing mid-/hindbrain region.Pfister, H. ; Ollert, M. ; Fröhlich, L.F. ; Quintanilla-Martinez, L. ; Colby, T.V. ; Specks, U. ; Jenne, D.
Antineutrophil cytoplasmic autoantibodies against the murine homolog of proteinase 3 (Wegener autoantigen) are pathogenic in vivo.Schofield, P.N. ; Bard, J.B.L. ; Booth, C. ; Boniver, J. ; Covelli, V. ; Delvenne, P. ; Ellender, M. ; Engstrom, W. ; Goessner, W. ; Gruenberger, M. ; Höfler, H.
Pathbase: A database of mutant mouse pathology.Mancuso, M. ; Pazzaglia, S. ; Tanori, M. ; Hahn, H. ; Merola, P. ; Rebessi, S. ; Atkinson, M.J. ; di Majo, V. ; Covelli, V. ; Saran, A.
Basal cell carcinoma and its development: Insights from radiation-induced tumors in Ptch1-deficient mice.Jütting, U. ; Hense, B.A. ; Rodenacker, K. ; Gais, P.
(Teil-)automatisierte Analyse der Phytoplankton-Zusammensetzung nach der Utermöhl-Methode.Engelhard, K. ; Werner, C. ; Eberspächer, E. ; Pape, M. ; Blobner, M. ; Hutzler, P. ; Kochs, E.
Sevoflurane and Propofol influence the expression of apoptosis-regulating proteins after cerebral ischaemia and reperfusion in rats.Fuchs, M. ; Hutzler, P. ; Handschuh, G. ; Hermannstädter, C. ; Brunner, I. ; Höfler, H. ; Luber, B.
Dynamics of cell adhesion and motility in living cells is altered by single amino acid change in E-cadherin fused to enhanced green fluorescent protein.Massberg, S. ; Grüner, S. ; Konrad, I. ; Arguinzonis, M.I.G. ; Eigenthaler, M. ; Hemler, K. ; Kersting, J. ; Schulz, C. ; Müller, I. ; Besta, F. ; Nieswandt, B.
Enhanced in vivo platelet adhesion in vasodilator-stimulated phosphoprotein (VASP)-deficient mice.Kappler, R. ; Bauer, R. ; Calzada-Wack, J. ; Rosemann, M. ; Hemmerlein, B. ; Hahn, H.
Profiling the molecular difference between Patched- and p53-dependent rhabdomyosarcoma.Kokubu, C. ; Heinzmann, U. ; Kokubu, T. ; Sakai, N. ; Kubota, T. ; Kawai, M. ; Wahl, M.B. ; Galceran, J. ; Grosschedl, R. ; Ozono, K. ; Imai, K.
Skeletal defects in ringelschwanz mutant mice reveal that Lrp6 is required for proper somitogenesis and osteogenesis.Kirschnek, S. ; Scheffel, J. ; Heinzmann, U. ; Häcker, G.
Necrosis-like cell death induced by bacteria in mouse macrophages.Sørensen, K.D. ; Quintanilla-Martinez, L. ; Kunder, S. ; Schmidt, J. ; Pedersen, F.S.
Mutation of all runx (AML1/Core) sites in the enhancer of T-lymphomagenic SL3-3 murine leukemia virus unmasks a significant potential for myeloid leukemia induction and favors enhancer evolution toward induction of other disease patterns.Glaser, B. ; Shirneshan, K. ; Bink, K. ; Wirth, J. ; Kehrer-Sawatzki, H. ; Bartz, U. ; Zoll, B. ; Bohlander, S.K.
Molecular cytogenetic analysis of a de novo balanced X;autosome translocation: Evidence for predominant inactivation of the derivative X chromosome in a girl with multiple malformations.Walch, A.K. ; Specht, K. ; Braselmann, H. ; Stein, H. ; Siewert, J.R. ; Hopt, U. ; Höfler, H. ; Werner, M.
Coamplification and coexpression of GRB7 and ERBB2 is found in high grade intraepithelial neoplasia and in invasive Barrett's carcinoma.Hieber, L. ; Zitzelsberger, H.
Molecular genetic mechanisms of radiocarcinogenesis and predictive markers for radioresistance in tumors - present work and future perspectives.Möbius, C. ; Stein, H.J. ; Becker, I. ; Feith, M. ; Theisen, J. ; Gais, P. ; Jütting, U. ; Siewert, J.R.
Vascular endothelial growth factor expression and neovascularization in Barrett's carcinoma.Laux, H. ; Tomer, R. ; Mader, M.T. ; Smida, J. ; Budczies, J. ; Kappler, R. ; Hahn, H. ; Blöchinger, M. ; Schnitzbauer, U. ; Eckardt-Schupp, F. ; Höfler, H.
Tumor-associated E-cadherin mutations do not induce Wnt target gene expression, but affect E-cadherin repressors.Hahn, H. ; Nitzki, F. ; Schorban, T. ; Hemmerlein, B. ; Threadgill, D. ; Rosemann, M.
Genetic mapping of a Ptch1-associated rhabdomyosarcoma susceptibility locus on mouse chromosome 2.Buschmann, H. ; Fabri, C.O. ; Hauptmann, M. ; Hutzler, P. ; Laux, Th. ; Lloyd, C.W. ; Schäffner, A.
Helical growth of the Arabidopsis mutant tortifolia1 reveals a plant-specific microtubule-associated protein.Hoffmann, I. ; Schäffer, E.H. ; Reese, S. ; Köstlin, R.
Die sonographische Untersuchung des vorderen Augenabschnittes beim Kleintier. Teil 2: Pathologische Befunde.Rosivatz, E. ; Becker, I. ; Bamba, M. ; Schott, C. ; Diebold, J. ; Mayr, D. ; Höfler, H. ; Becker, K.-F.
Neoexpression of N-cadherin in E-cadherin positive colon cancers.Pirker, C. ; Raidl, M. ; Steiner, E. ; Elbling, L. ; Holzmann, K. ; Spiegl-Kreinecker, S. ; Aubele, M. ; Grasl-Kraupp, B. ; Marosi, C. ; Miksche, M. ; Berger, W.
Whole genome amplification for CGH analysis: Linker-adapter PCR as the method of choice for difficult and limited samples.Allgoewer, I. ; Schäffer, E.H.
Hornhautveränderung bei einer British-Shorthair-Katze.Specht, K. ; Haralambieva, E. ; Bink, K. ; Kremer, M. ; Mandl-Weber, S. ; Koch, I. ; Tomer, R. ; Höfler, H. ; Schuuring, E. ; Kluin, P.M. ; Fend, F.
Different mechanisms of cyclin D1 overexpression in multiple myeloma revealed by fluorescence in situ hybridization and quantitative analysis of mRNA levels.Raidl, M. ; Pirker, C. ; Schulte-Hermann, R. ; Aubele, M. ; Kandioler-Eckersberger, D. ; Wrba, F. ; Micksche, M. ; Berger, W. ; Grasl-Kraupp, B.
Multiple chromosomal abnormalities in human liver (pre)neoplasia.Pazzaglia, S. ; Mancuso, M. ; Tanori, M. ; Atkinson, M.J. ; Merola, P. ; Rebessi, S. ; di Majo, V. ; Covelli, V. ; Hahn, H. ; Saran, A.
Modulation of patched-associated susceptibility to radiation induced tumorigenesis by genetic background.Gamboa-Dominguez, A. ; Dominguez-Fonseca, C. ; Quintanilla-Martinez, L. ; Reyes-Gutierrez, E. ; Green, D. ; Angeles-Angeles, A. ; Busch, R. ; Hermannstädter, Ch. ; Nährig, J. ; Becker, K.-F. ; Becker, I.
Epidermal growth factor receptor expression correlates with poor survival in gastric adenocarcinoma from Mexican patients: A multivariate analysis using a standardized immunohistochemical detection system.Piotrowska, K. ; Pellegata, N.S. ; Rosemann, M. ; Fritz, A. ; Graw, J. ; Atkinson, M.J.
Mapping of a novel MEN-like syndrome locus to rat Chromosome 4.Klein, D. ; Arora, U. ; Lichtmannegger, J. ; Finckh, M. ; Heinzmann, U. ; Summer, K.H.
Tetrathiomolybdate in the treatment of acute hepatitis in an animal model for Wilson disease.Rawat, V.P.S. ; Cusan, M. ; Deshpande, A. ; Hiddemann, W. ; Quintanilla-Martinez, L. ; Humphries, R.K. ; Bohlander, S.K. ; Feuring-Buske, M. ; Buske, C.
Ectopic expression of the homeobox gene Cdx2 is the transforming event in a mouse model of t(12;13)(p13;q12) acute myeloid leukemia.Massberg, S. ; Konrad, I. ; Bültmann, A. ; Schulz, C. ; Münch, G. ; Peluso, M. ; Lorenz, M. ; Schneider, S. ; Besta, F. ; Müller, I. ; Hu, B. ; Langer, H. ; Kremmer, E.
Soluble glycoprotein VI dimer inhibits platelet adhesion and aggregation to the injured vessel wall in vivo.Eberspächer, E. ; Werner, C. ; Engelhard, K. ; Pape, M. ; Gelb, A. ; Hutzler, P. ; Henke, J. ; Kochs, E.
The effect of hyperthermia on the expression of the apoptosis-regulating protein Bax after incomplete cerebral ischemia and reperfusion in rats.Möbius, C. ; Stein, H.J. ; Becker, I. ; Feith, M. ; Theisen, J. ; Gais, P. ; Jütting, U. ; Siewert, J.R.
The 'angiogenic switch' in the progression from Barret's metaplasia to esophageal adenocarcinoma.Schäffer, E.H. ; Quintanilla-Martinez, L. ; Marquart, K.-H.
Okulare Manifestation der malignen Histiozytose beim Berner Sennenhund.Kremer, M. ; Quintanilla-Martinez, L. ; Fuchs, M. ; Gamboa-Dominguez, A. ; Haye, S. ; Kalthoff, H. ; Rosivatz, E. ; Hermannstädter, C. ; Busch, R. ; Höfler, H. ; Luber, B.
Influence of tumor-associated E-cadherin mutations on tumorgenicity and metastasis.Ma, S.L. ; Lovmand, J. ; Sorensen, A.B. ; Luz, A. ; Schmidt, J. ; Pedersen, F.S.
Triple basepair changes within and adjacent to the conserved YY1 motif upstream of the U3 enhancer repeats SL3-3 murine leukemia virus cause a small but significant shortening of latency of T-lymphoma induction.Massberg, S. ; Gawaz, M. ; Grüner, S. ; Schulte, V. ; Konrad, I. ; Zohlnhöfer, D. ; Heinzmann, U. ; Nieswandt, B.
A crucial role of glycoprotein VI for platelet recruitment to the injured arterial wall in vivo.Daldrup-Link, H.E. ; Rudelius, M. ; Oostendorp, R.A.J. ; Settles, M. ; Piontek, G. ; Metz, S. ; Rosenbrock, H. ; Keller, U. ; Heinzmann, U. ; Rummeny, E.J. ; Schlegel, J. ; Link, T.M.
Targeting of Hematopoitic Progenitor Cells with MR Contrast Agents1.Hapke, S. ; Kessler, H. ; Luber, B. ; Benge, A. ; Hutzler, P. ; Höfler, H. ; Schmitt, M. ; Reuning, U.
Ovarian Cancer Cell Proliferation and Motility is Induced by Engagement of Integrin alphavß3/ Vitronectin Interaction.Braselmann, H. ; Kulka, U. ; Huber, R. ; Figel, A.-M. ; Zitzelsberger, H.
Distribution of radiation-induced exchange aberrations in all human chromosomes.Richter, H. ; Slezak, P. ; Walch, A.K. ; Werner, M. ; Braselmann, H. ; Jaramillo, E. ; Öst, A. ; Hirata, I. ; Takahama, K. ; Zitzelsberger, H.
Distinct Chromosomal Imbalances in Nonpolypoid and Polypoid Colorectal Adenomas Indicate Different Genetic Pathways in the Development of Colorectal Neoplasms.Fend, F. ; Kremer, M. ; Specht, K. ; Quintanilla-Martinez, L.
Laser Microdissection in Hematopathology.Aubele, M. ; Smida, J.
Degenerate Oligonucleotide-Primed PCR.Neu, B. ; Puschmann, A.J. ; Mayerhofer, A. ; Hutzler, P. ; Grossmann, J. ; Lippl, F. ; Schepp, W. ; Prinz, C.
TNF-alpha induces apoptosis of parietal cells.Barthel, M. ; Hapfelmeier, S. ; Quintanilla-Martinez, L. ; Kremer, M. ; Rohde, M. ; Hogardt, M. ; Pfeffer, K. ; Rüssmann, H. ; Hardt, W.-D.
Pretreatment of Mice with Streptomycin Provides a Salmonella enterica Serovar Typhimurium Colitis Model that Allows Analysis of Both Pathogen and Host.Kappler, R. ; Calzada-Wack, J. ; Schnitzbauer, U. ; Koleva, M. ; Herwig, A. ; Piontek, G. ; Graedler, F. ; Adamski, J. ; Heinzmann, U. ; Schlegel, J. ; Hemmerlein, B. ; Quintanilla-Martinez, L. ; Hahn, H.
Molecular characterization of Patched-associated rhabdomyosarcoma.Bogner, C. ; Ringshausen, I. ; Schneller, F. ; Fend, F. ; Quintanilla-Martinez, L. ; Häcker, G. ; Goetze, K. ; Oostendorp, R. ; Peschel, C.
Inhibition of the proteasome induces cell cycle arrest and apoptosis in mantle cell lymphoma cells.Przemeck, G.K.H. ; Heinzmann, U. ; Beckers, J. ; Hrabě de Angelis, M.
Node and midline defects are associated with left-right development in Delta1 mutant embryos.Barthel, M. ; Hapfelmeier, S. ; Quintanilla-Martinez, L. ; Kremer, M. ; Rohde, M. ; Hogardt, M. ; Pfeffer, K. ; Rüssmann, H. ; Hardt, W.-D.
Pretreatment of Mice with Streptomycin a Salmonella enterica Serovar Typhimurium Colitis Model that Allows Analysis of Both Pathogen and Host.Quintanilla-Martinez, L. ; Kremer, M. ; Specht, K. ; Calzada-Wack, J. ; Nathrath, M. ; Schaich, R. ; Höfler, H. ; Fend, F.
Analysis of Signal Transducer and Activator of Transcription 3 (Stat 3) Pathway in Multiple Myeloma : Stat 3 Activation and Cyclin D1 Dysregulation Are Mutually Exclusive Events.Rosemann, M. ; Kuosaite, V. ; Nathrath, M. ; Strom, T.M. ; Quintanilla-Martinez, L. ; Richter, T. ; Imai, K. ; Atkinson, M.J.
Allelic imbalance at intragenic markers of Tbx18 is a hallmark of murine osteosarcoma.Quintanilla-Martinez, L. ; Davies-Hill, T. ; Fend, F. ; Calzada-Wack, J. ; Sorbara, L. ; Campo, E. ; Jaffe, E.S. ; Raffeld, M.
Sequestration of p27Kip1 protein by cyclin D1 in typical and blastic variants of mantle cell lymphoma (MCL) : Implications for pathogenesis.Buters, J. ; Quintanilla-Martinez, L. ; Schober, W. ; Soballa, V.J. ; Hintermair, J. ; Wolff, T. ; Gonzalez, F.J. ; Greim, H.
CYP1B1 determines susceptibility to low doses of 7,12-dimethylbenz[a]anthracene-induced ovarian cancers in mice : Correlation of CYP1B1-mediated DNA adducts with carcinogenicity.Engelhard, K. ; Werner, C. ; Eberspächer, E. ; Bachl, M. ; Blobner, M. ; Hildt, E. ; Hutzler, P. ; Kochs, E.
The Effect of the alpha2-Agonist Dexmedetomidine and the N-Methyl-d-Aspartate Antagonist S(+ )-Ketamine on the Expression of Apoptosis-Regulating Proteins After Incomplete Cerebral Ischemia and Reperfusion in Rats.Kremer, M. ; Spitzer, M. ; Mandl-Weber, S. ; Stecker, K. ; Schmidt, B. ; Höfler, H. ; Quintanilla-Martinez, L. ; Fend, F.
Discordant Bone Marrow Involvement in Diffuse Large B-Cell Lymphoma : Comparative Molecular Analysis Reveals a Heterogeneous Group of Disorders.Waidelich, W. ; Hutzler, P.J.S. ; Waidelich, R.
Detection of abnormal cells by optical image processing.Frick, S.
Zur Dignitätsbewertung des primär-intraokularen Melanoms bei Hund und Katze.Gössner, W.
A brief history of the Society for Histochemistry : its founders, its mission and the first 50 years.Calzada-Wack, J. ; Schnitzbauer, U. ; Walch, A.K. ; Wurster, K.-H. ; Kappler, R. ; Nathrath, M. ; Hahn, H.
Analysis of the PTCH Coding Region in Human Rhabdomyosarcoma.Wittmaack, K. ; Menzel, N. ; Wehnes, H. ; Heinzmann, U.
Phase separation and regrowth of aerosol matter collected after size fractionation in an impactor.Pazzaglia, S. ; Mancuso, M. ; Atkinson, M.J. ; Tanori, M. ; Rebessi, S. ; di Majo, V. ; Covelli, V. ; Hahn, H. ; Saran, A.
High incidence of medulloblastoma following X-ray-irradiation of newborn Ptc1 heterozygous mice.Fend, F. ; Specht, K. ; Kremer, M. ; Quintanilla-Martinez, L.
Laser Capture Microdissection in Pathology.Siggelkow, H. ; Schenck, M. ; Rohde, M. ; Viereck, V. ; Tauber, S. ; Atkinson, M.J. ; Hüfner, M.
Prolonged Culture of HOS 58 Human Osteosarcoma Cells with 1,25-(OH)2-D3, TGF-Beta and Dexamethasone Reveals Physiological Regulation of Alkaline Phosphatase, Dissociated Osteocalcin Gene Expression and Protein Synthesis and Lack of Mineralization.Aubele, M. ; Werner, M. ; Höfler, H.
Genetic alterations in presumptive precursor lesions of breast carcinomas.Gerber, J.-K. ; Richter, T. ; Kremmer, E. ; Adamski, J. ; Höfler, H. ; Balling, R. ; Peters, H.
Progressive loss of PAX9 expression correlates with increasing malignancy of dysplastic and cancerous epithelium of the human oesophagus.Tippe, A. ; Heinzmann, U. ; Roth, C.
Deposition of fine and ultrafine aerosol particles during exposure at the air/cell interface.Rosivatz, E. ; Becker, I. ; Specht, K. ; Fricke, E. ; Luber, B. ; Busch, R. ; Höfler, H. ; Becker, K.-F.
Differential Expression of the Epithelial-Mesenchymal Transition Regulators Snail, SIP1 and Twist in Gastric Cancer.Pharoah, P.D.P. ; Oliveira, C. ; Machado, J.C. ; Keller, G. ; Vogelsang, H. ; Laux, H. ; Becker, K.-F. ; Hahn, H. ; Paproski, S.M. ; Brown, L.A. ; Caldas, C. ; Huntsmann, D.
CDH1 c-160a Promotor Polymorphism is not associated with risk of stomach cancer.da Costa, C.P. ; Kirschning, C.J. ; Busch, D.H. ; Dürr, S. ; Jennen, L. ; Heinzmann, U. ; Prebeck, S. ; Wagner, H.M. ; Miethke, T.
Role of chlamydial heat shock protein 60 in the stimulation of innate immune cells by Chlamydia pneumoniae.Patel, V. ; Lahusen, T. ; Leethanakul, C. ; Igishi, T. ; Kremer, M. ; Quintanilla-Martinez, L. ; Ensley, J.F. ; Sausville, E.A. ; Gutkind, J.S. ; Senderowicz, A.M.
Antitumor activity of UCN-01 in carcinomas of the head and neck is associated with altered expression of cyclin D3 and p27KIP1.Nathrath, M. ; Kuosaite, V. ; Rosemann, M. ; Kremer, M. ; Poremba, Ch. ; Wakana, S. ; Yanagi, M. ; Nathrath, W.B.J. ; Höfler, H. ; Imai, K. ; Atkinson, M.J.
Two novel tumor suppressor gene loci on chromosome 6q and 15q in human osteosarcoma identified through comparative study of allelic imbalances in mouse and man.Fuchs, M. ; Hutzler, P. ; Brunner, I. ; Schlegel, ; Mages, J. ; Reuning, U. ; Hapke, S. ; Duyster, J. ; Hirohashi, S. ; Genda, T. ; Sakamoto, M. ; Überall, F. ; Höfler, H. ; Becker, K.-H. ; Luber, B.
Motility Enhancement by Tumor-Derived Mutant E-Cadherin is Sensitive to Treatment with Epidermal Growth Factor Receptor and Phosphatidylinositol 3-Kinase Inhibitors.Fend, F. ; Martinez, A. ; Quintanilla-Martinez, L. ; Sanz, L. ; Combalia, N. ; Raffeld, M. ; Jaffe, E.S. ; Montserrat, E. ; Campo, E.
Clonally unrelated Hodkin's disease following autologous stem cell transplant for B-cell lymphoma.Vecsey-Semjen, B. ; Becker, K.-F. ; Sinski, A. ; Blennow, E. ; Vietor, I. ; Zatloukal, K. ; Beug, H. ; Wagner, E. ; Huber, L.A.
Novel colon cancer cell lines leading to better understanding of the diversity of respective primary cancers.Bange, J. ; Prechtl, D. ; Cheburkin, Y. ; Specht, K. ; Harbeck, N. ; Schmitt, M. ; Knyazeva, T. ; Müller, S. ; Gärtner, S. ; Sures, I. ; Wang, H. ; Imyanitov, E. ; Häring, H.-U. ; Knayzev, P. ; Iacobelli, S. ; Höfler, H. ; Ullrich, A.
Cancer Progression and Tumor Cell Motility Are Associated with the FGFR4 Arg388 Allele.Allgoewer, I. ; Göbel, Th. ; Stockhaus, Ch. ; Schaeffer, E.H.
Dacryops in a red-eared slider (Chrysemys scripta elegans) : Case report.Wappler, O. ; Allgoewer, I. ; Schäffer, E.H.
Conjunctival dermoid in two guinea pigs : A case report.Rosemann, M. ; Kuosaite, V. ; Nathrath, M. ; Atkinson, M.J.
The genetics of radiation-induced and sporadic osteosarcoma : A unifying theory ?.Rosemann, M. ; Kuosaite, V. ; Nathrath, M. ; Atkinson, M.J.
The Genetics of Radiation-Induced Osteosarcoma.Specht, K. ; Kremer, M. ; Müller, U. ; Dirnhofer, S. ; Rosemann, M. ; Höfler, H. ; Quintanilla-Martinez, L. ; Fend, F.
Identification of Cyclin D1 mRNA Overexpression in B-Cell Neoplasias by Real-Time Reverse Transcription-PCR of Microdissected Paraffin Sections.Buters, J.T.M. ; Mahadevan, B. ; Quintanilla-Martinez, L. ; Gonzales, F.J. ; Greim, H. ; Baird, W.M. ; Luch, A.
Cytochrome P450 1B1 Determines Susceptibility to Dibenzo[a,l]pyrene-Induced Tumor Formation.Nathrath, M. ; Kremer, M. ; Letzel, H. ; Remberger, K. ; Höfler, H. ; Ulle, T.
Expression von Genen mit möglicher prognostischer Bedeutung für das Ansprechen auf Chemotherapie bei Patienten mit Osteosarkom : Gene mit möglicher prognostischer Bedeutung beim Osteosarkom.Rosemann, M. ; Lintrop, M. ; Favor, J. ; Atkinson, M.J.
Bone tumorigenesis induced by alpha-particle radiation: Mapping of genetic loci influencing predisposition in mice.Lubeseder-Martellato, C. ; Guenzi, E. ; Jörg, A. ; Töpolt, K. ; Naschberger, E. ; Kremmer, E. ; Zietz, C. ; Tschachler, E. ; Hutzler, P. ; Schwemmle, M. ; Matzen, K. ; Grimm, Th. ; Ensoli, B.
Guanylate-Binding Protein-1 Expression is Selectively Induced by Inflammatory Cytokines and is an Activation Marker of Endothelial Cells during Inflammatory Diseases.Nößner, E. ; Gastpar, R. ; Milani, V. ; Brandl, A. ; Hutzler, P.J.S. ; Kuppner, M.C. ; Roos, M. ; Kremmer, E. ; Asea, A. ; Calderwood, S.K. ; Issels, R.D.
Tumor-Derived Heat Shock Protein 70 Peptide Complexes Are Cross-Presented by Human Dendritic Cells.Fritz, A. ; Walch, A.K. ; Piotrowska, K. ; Rosemann, M. ; Schäffer, E.H. ; Weber, K. ; Timper, A. ; Wildner, G. ; Graw, J. ; Höfler, H. ; Atkinson, M.J.
Recessive Transmission of a Multiple Endocrine Neoplasia Syndrome in the Rat.Lohrer, H.D. ; Hieber, L. ; Zitzelsberger, H.
Differential mutation frequency in mitochondrial DNA from thyroid tumours.Aubele, M. ; Auer, G. ; Braselmann, H. ; Nährig, J. ; Zitzelsberger, H. ; Quintanilla-Martinez, L. ; Smida, J. ; Höfler, H. ; Werner, M.
Chromosomal imbalances are associated with metastasis-free survival in breast cancer patients.Allgoewer, I. ; Schäffer, E.H. ; Strauß, G. ; Ochs, A.
Die Galaktosämie-Katarakt beim Känguru.Becker, K.-F. ; Kremmer, E. ; Eulitz, M. ; Schulz, St. ; Mages, J. ; Handschuh, G. ; Wheelock, M.J. ; Cleton-Jansen, A.-M. ; Höfler, H. ; Becker, I.
Functional allelic loss detected at the protein level in archival human tumours using allele-specific E-cadherin monoclonal antibodies.Schmittenbecher, P.P. ; Schuster, F. ; Heinz-Erian, P. ; Gais, P.
Colonic mucosal vasoactive intestinal peptide receptors in malformations of the enteric nervous system are reduced compared with morphologically normal innervated colon.Eising, G.P. ; Schad, H. ; Heimisch, W. ; Bernhard-Abt, A. ; Ettner, U. ; Schäffer, E.H. ; Tassani, P. ; Mendler, N. ; Lange, R.
Isovolumische Hämofiltration während und nach extrakorporaler Zirkulation kann die kardiopulmonale Funktion nicht verbessern.Calzada-Wack, J. ; Kappler, R. ; Schnitzbauer, U. ; Richter, T. ; Nathrath, M. ; Rosemann, M. ; Wagner, S.N. ; Hein, R. ; Hahn, H.
Unbalanced overexpression of the mutant allele in murine Patched mutants.Kohleisen, B. ; Hutzler, P. ; Shumay, E. ; Ovod, V. ; Erfle, V.
HIV-1 Nef co-localizes with the astrocyte-specific cytoskeleton protein GFAP in persistently nef- expressing human astrocytes.Rodenacker, K. ; Gais, P. ; Jütting, U. ; Hense, B.A.
(Semi-)Automatic recognition of microorganisms in water.Walch, A.K. ; Specht, K. ; Smida, J. ; Aubele, M. ; Zitzelsberger, H. ; Höfler, H. ; Werner, M.
Tissue microdissection techniques in quantitative genome and gene expression analyses.Grimm, Th. ; Stürzl, M. ; Jennen, L.
HIV-1 und HHV-8 : eine tumorigene Allianz in der Pathogenese des Kaposi-Sarkoms.Bink, K. ; Walch, A.K. ; Feuchtinger, A. ; Eisenmann, H. ; Hutzler, P. ; Höfler, H. ; Werner, M.
TO-PRO-3 is an optimal fluorescent dye for nuclear counterstaining in dual-colour FISH on paraffin sections.Neu, B. ; Herrmuth, H. ; Ernst, F. ; Vaupel, W. ; Reindl, W. ; Hutzler, P. ; Atkinson, M.J. ; Classen, M. ; Schepp, W.
Differential Expression of CD95, Bcl-2 and Bax in Rat Gastric Chief and Parietal Cells.Zitzelsberger, H. ; Engert, D. ; Walch, A.K. ; Kulka, U. ; Aubele, M. ; Höfler, H. ; Bauchinger, M. ; Werner, M.
Chromosomal changes during development and progression of prostate adenocarcinomas.Werner, M. ; Becker, K.F. ; Keller, G. ; Höfler, H.
Gastric adenocarcinoma : Pathomorphology and molecular pathology.Walch, A.K. ; Specht, K. ; Bink, K. ; Zitzelsberger, H. ; Braselmann, H. ; Bauer, M. ; Aubele, M. ; Stein, H. ; Siewert, J.R. ; Höfler, H. ; Werner, M.
Her-2/neu gene amplification, elevated mRNA expression, and protein overexpression in the metaplasia-dysplasia-adenocarcinoma sequence of Barrett's esophagus.Walch, A.K. ; Bink, K. ; Hutzler, P. ; Böwering, K. ; Letsiou, I. ; Zitzelsberger, H. ; Braselmann, H. ; Stein, H. ; Höfler, H. ; Werner, M.
Sequential multilocus fluorescence in situ hybridization can detect complex patterns of increased gene dosage at the single cell level in tissue sections.Chalmers, I.J. ; Aubele, M. ; Hartmann, E. ; Braungart, E. ; Werner, M. ; Höfler, H. ; Atkinson, M.J.
Mapping the Chromosome 16 Cadherin Gene Cluster to a minimal deleted Region in Ductal Breast Cancer.Jütting, U. ; Gais, P. ; Rodenacker, K. ; Böhm, J. ; Höfler, H.
MIB-1, AgNOR and DNA distribution parameters and their prognostic value in neuroendocrine tumours of the lung.Yanagi, M. ; Keller, G. ; Müller, J. ; Walch, A.K. ; Werner, M. ; Stein, H.J. ; Siewert, J.R. ; Höfler, H.
Comparison of loss of heterozygosity and microsatellite instability in adenocarcinomas of the distal esophagus and proximal stomach.Debbage, P.L. ; Seidl, S. ; Kreczy, A. ; Hutzler, P. ; Pavelka, M. ; Lukas, P.
Vascular permeability and hyperpermeability in a murine adenocarcinoma after fractionated radiotherapy : an ultrastructural tracer study.Fend, F. ; Kremer, M. ; Quintanilla-Martinez, L.
Laser Capture Microdissection : Methodical Aspects and Applications with Emphasis on Immuno-Laser Capture Microdissection.Majzoub, M. ; Schmidt, P. ; Hafner, A. ; Schäffer, E.H. ; Gerhards, H. ; Hermanns, W.
Halicephalobus deletrix : Infektion bei zwei Pferden.Zhou, B. ; Jütting, U. ; Rodenacker, K. ; Gais, P.
Prediction of the Outcome of Esophageal Epithelium Dysplasia by High Resolution Image Analysis.Walch, A.K. ; Zitzelsberger, H. ; Bruch, J. ; Keller, G. ; Angermeier, D. ; Aubele, M. ; Müller, J. ; Stein, H. ; Braselmann, H. ; Siewert, J.R. ; Höfler, H. ; Werner, M.
Chromosomal imbalances in Barrett's adenocarcinoma and the metaplasia-dysplasia-carcinoma sequence.Walch, A.K. ; Zitzelsberger, H. ; Bink, K. ; Hutzler, P. ; Bruch, J. ; Braselmann, H. ; Aubele, M. ; Müller, J. ; Stein, H. ; Siewert, J.R. ; Höfler, H. ; Werner, M.
Molecular genetic changes in metastatic primary Barrett's adenocarcinoma and related lymph node metastases: Comparison with nonmetastatic Barrett's adenocarcinoma.Aubele, M. ; Cummings, M.C. ; Mattis, A.E. ; Zitzelsberger, H. ; Walch, A.K. ; Kremer, M. ; Höfler, H. ; Werner, M.
Accumulation of chromosomal imbalances from intraductal proliferative lesions to adjacent in situ and invasive ductal breast cancer.Aubele, M. ; Mattis, A. ; Zitzelsberger, H. ; Walch, A.K. ; Kremer, M. ; Welzl, G. ; Höfler, H. ; Werner, M.
Extensive ductal carcinoma in situ with small foci of invasive ductal carcinoma: Evidence of genetic resemblance by CGH.Aubele, M. ; Cummings, M. ; Walch, A.K. ; Zitzelsberger, H. ; Nährig, J. ; Höfler, H. ; Werner, M.
Heterogeneous chromosomal aberrations in intraductal breast lesions adjacent to invasive carcinoma.Hrabě de Angelis, M. ; Flaswinkel, H. ; Fuchs, H. ; Rathkolb, B. ; Soewarto, D. ; Marschall, S. ; Heffner, S. ; Pargent, W. ; Wuensch, K. ; Jung, M. ; Reis, A. ; Richter, T. ; Alessandrini, F. ; Jakob, T. ; Fuchs, E. ; Kolb, H. ; Kremmer, E. ; Schäble, K.-H. ; Rollinski, B. ; Roscher, A. ; Peters, C. ; Meitinger, T. ; Strom, T.M. ; Steckler, T. ; Holsboer, F. ; Klopstock, T. ; Gekeler, F. ; Schindewolf, C. ; Jung, T. ; Avraham, K. ; Behrendt, H. ; Ring, J. ; Zimmer, A. ; Schughart, K. ; Pfeffer, K. ; Wolf, E. ; Balling, R.
Genome-wide, large-scale production of mutant mice by ENU mutagenesis.Takenaka, S. ; Karg, E.W. ; Möller, W. ; Roth, C. ; Ziesenis, A. ; Heinzmann, U. ; Schramel, P. ; Heyder, J.
A morphologic study on the fate of ultrafine silver particles : Distribution pattern of phagocytized metallic silver in vitro and in vivo.