Bioengineering Center Biological and Medical Imaging

In the Nanomedicine and Biomarkers Group, we study preclinical models of disease with label-free MSOT imaging to develop working pipelines for in vivo detection and quantification of biomarkers, such as lipid content, blood perfusion, and tissue oxygenation.

The research group for Molecular Engineering focuses on enabling this rich variety of tools for opto-acoustic (OA) imaging. OA is an emerging methodology bridging light excitation and ultrasound detection towards deep tissue imaging.

At the group for "AI in Optoacoustics" of IBMI, we design innovative algorithms for biomedical imaging modalities based on sophisticated mathematical models.

The Laboratory develops advanced fluorescence imaging methods for pre-clinical and clinical imaging, leading in 2011 to the first clinical translation of a targeted fluorescent agent for optical molecular imaging of patients.

Our group’s primary research interest is to understand the mechanobiology of the airway epithelium.

Our group conceives, designs and develops multispectral optoacoustic technology that allows performing non-invasive anatomical, functional and molecular optical imaging of the skin in the clinics.

Our research innovates hybrid methods combining thermoacoustic, optoacoustic and fluorescence imaging.

Our group focuses on developing technology and applications on the combination of optical and optoacoustic microscopy in order to deliver contrast and imaging abilities not available in optical microscopes today.

The group „IBMI Biology Central Support“ is centered around provision and development of cell lines and animal models for optoacoustic imaging.

We are developing methods and devices to measure health-related parameters non-invasively. Just imagine getting your blood work done without any needles, but by using light and by sensing the resulting ultrasound waves on your skin surface. Chemical contrast is achieved label-free by the wavelength-specific absorption of relevant molecules.

Our research innovates hybrid methods combining thermoacoustic, optoacoustic and fluorescence imaging. Fueled by a DFG Koselleck award, and BMBF support (Tech2See, Sense4Life) award we innovate in three main areas; (1) We interrogate the fundamental interactions of electromagnetic (EM) and optical energy and tissue and exploit them for sensing applications. (2) We research novel instrumentation designs for optimal illumination and energy coupling to tissue for sensing and therapeutic applications and (3) develop novel classes of sensors (including nanoparticles and novel sensing devices) for reading pathophysiological features of tissue, indicative of disease aiming to generate novel early detection paradigms. System development, data processing and in-vivo monitoring of biophysical processes are among the focus of our research group. Research from this group further feeds technological solutions in other research groups in the Chair and Institute.