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Molecular Targets and Therapeutics Center Institute of Virology

The institute's research activities focus on the molecular understanding of virus-host interactions. Based on this understanding, we develop and improve therapeutic strategies for viral infections and related diseases.

The institute's research activities focus on the molecular understanding of virus-host interactions. Based on this understanding, we develop and improve therapeutic strategies for viral infections and related diseases.

Our Research Groups

Helmholtz Munich | Stefanie Winkler
Protzer Lab

Chronic viral hepatitis

Our scientific interest is to better understand the interaction of hepatitis B (HBV) and C (HCV) virus with their host and to develop new therapeutic strategies to treat chronic viral hepatitis and hepatocellular carcinoma.

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Vincendeau Lab

Human Endogenous Retroviruses

The aim of our research is to elucidate the functional role of HERVs during stem cell differentiation and brain development using cutting-edge technologies including advanced CRISPR techniques in combination with human stem cell differentiation, the generation of brain organoids (mini brains in the dish) and bioinformatics analysis of large datasets.

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Ebert Lab

Cell Signaling and Cell Death

Our lab is interested in the study of cell signaling pathways related to cell death and inflammation manipulated during host-pathogen interactions for novel therapeutic development.

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Deng Lab

Virus in nature and health

The Deng lab uses an integrative approach combining single-cell technologies, culture-independent techniques, multi-omics, and machine learning to understand the underlying mechanisms of phage-host interactions and their impact on the human host. Ultimately, we aim to develop personalized phage-based treatments against multiple human diseases and conditions.

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Bauer Lab

Immunmonitoring

The main focus of our research is the analysis of the phenotype and functional properties of different immune cell populations mainly in the context of clinical trials. By doing so, we are aiming for an in depth understanding of cellular virus-host interactions to support the development of novel therapeutic interventions, e.g. by prediction of biomarker that identifies target engagement and predicts response to therapeutic interventions.

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Nößner Lab

Tissue control of Immunocytes

Research unit IMA-TCI studies the interaction of immunocytes with aberrant tissue cells in kidney liver and lung to provide new hypothesis for therapy improvement. Immune monitoring accompanying clinical trials shall identify new prognostic and predictive markers.

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Mautner Lab

EBV immunity

Our research focus is on the immune response against the Epstein-Barr virus (EBV), and EBV-associated disease. With a better understanding of how immunity against EBV is established, we seek to establish predictive markers for the development and novel strategies for the treatment of virus-associated disorders.

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Our Scientists at Virology

Theresa Asen

Technical Assistant

Dr. Tanja Bauer

Supervisor

Robert Baier

Technical Assistant

Prof. Dr. Ruth Brack-Werner

Group Leader

Ute Finkel

Technical Assistant

Regina Geiger

Secretary

Dr. Nina Körber

Post Doc

Andrea Schmidbauer

Secretary

Dr. Frank Thiele

Postdoc

Jochen Wettengel

Rahim Mahmody

Lab Assistant

Jutta Lang

Member of Scullery Staff

Romina Bester

Dr. Sabrina Schreiner

Head of Group

Miona Stubbe

PhD Student

Peter Groitl

Senior Scientist

Dr. Michelle Vincendeau

Group Leader / Deputy Director of Institute

Prof. Dr. Li Deng

Group Leader

Shiqi Luo

PhD Student

Sophia Schreiber

PhD Student

Prof. Michael Roggendorf

Group Leader

Jinpeng Su

PhD Student

Dr. Anna Kosinska

Post Doc

Dr. Eva Loffredo-Verde

Post Doc

Prof. Andreas Pichlmair

Group Leader

Dr. Jinling Xue

Postdoc

Vidya Padmanabhan Nair

PostDoc

Sarah-Irina Pfeifer-Nigisch

Technical Assistant

Dr. Rita Costa

Postdoc

Wanqi Huang

PhD Student

Dr. Mohammadali Khan Mirzaei

Postdoc

Thi Anh Mai Pham

Master’s Student

Jinlong Ru

PhD Student

Sophie Smith

PhD Student

Kawtar Tiamani

PhD Student

Magdalena Unterer

PhD Student

Wen Liang

PhD Student

Van Lam

PhD Student

Hin-Man Tai

PhD Student

Silke Bernhöft

Technical Assistant

Judith Brehme

Administrative Assistant AG Deng

Chris Wesch

PhD Student

Corinna Winkler

PhD Student

Xue (Sherry) Peng

PhD Student

Adrian Thaqi

PhD Student

Dr. Gregor Ebert

Gruppenleiter

Friedrich Eugen Griessel

Intern

Monique Preusse

Technical Assistant

Jiawen Shi

Intern

Dr. Alexander Herrmann

Wissenschaftler

Olga Polezhaeva

Technician

Daniele Mistretta

Technician

Dr. Phuoc Hoa Le

Wissenschaftler

Lena Holzhäuser

Technician

Felix Esslinger

PhD Student

Niklas Kahler

Student

Julia Krebs

Student

Salih Özer

PhD Student

Lisa Hilberer

PhD Student

Catharina Strube

Student

Niels Tepho

Intern

Dr. Josef Mautner

Group Leader

Prof. Dr. Elfriede Nößner

Group Leader

Dr. Marian Wiegand

Project Manager

Dr. Fuwang Chen

Post Doc

Dr. Claudia Dembek

Project Manager

Fenna Kolbe

PhD Student

Susanne Miko

Technical Assistant

Manuela Laumer

Technical Assistant

Senadija Balic

Laboratory Assistant

Annika Willmann

MD student

Gesa Wilkens

MD student

Marinka Hrga

Laboratory Assistant

Lisa Pleninger

PhD Student

Bhavna Menon

Master Student
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Viruses studied at VIRO

Publications

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2022 Scientific Article in PLoS Genetics

Butler-Laporte, G. ; Povysil, G. ; Kosmicki, J.A. ; Cirulli, E.T. ; Drivas, T. ; Furini, S. ; Saad, C. ; Schmidt, A. ; Olszewski, P.K. ; Korotko, U. ; Quinodoz, M. ; Çelik, E. ; Kundu, K. ; Walter, K. ; Jung, J. ; Stockwell, A.D. ; Sloofman, L.G. ; Jordan, D.M. ; Thompson, R.C. ; Del Valle, D. ; Simons, N. ; Cheng, E. ; Sebra, R. ; Schadt, E.E. ; Kim-Schulze, S. ; Gnjatic, S. ; Merad, M. ; Buxbaum, J.D. ; Beckmann, N.D. ; Charney, A.W. ; Przychodzen, B. ; Chang, T. ; Pottinger, T.D. ; Shang, N. ; Brand, F. ; Fava, F. ; Mari, F. ; Chwialkowska, K. ; Niemira, M. ; Pula, S. ; Baillie, J.K. ; Stuckey, A. ; Salas, A. ; Bello, X. ; Pardo-Seco, J. ; Gómez-Carballa, A. ; Rivero-Calle, I. ; Martinón-Torres, F. ; Ganna, A. ; Karczewski, K.J. ; Veerapen, K. ; Bourgey, M. ; Bourque, G. ; Eveleigh, R.J. ; Forgetta, V. ; Morrison, D. ; Langlais, D. ; Lathrop, M. ; Mooser, V. ; Nakanishi, T. ; Frithiof, R. ; Hultström, M. ; Lipcsey, M. ; Marincevic-Zuniga, Y. ; Nordlund, J. ; Schiabor Barrett, K.M. ; Lee, W. ; Bolze, A. ; White, S. ; Riffle, S. ; Tanudjaja, F. ; Sandoval, E. ; Neveux, I. ; Dabe, S. ; Casadei, N. ; Motameny, S. ; Alaamery, M. ; Massadeh, S. ; Aljawini, N. ; Almutairi, M.S. ; Arabi, Y.M. ; Alqahtani, S.A. ; Al Harthi, F.S. ; Almutairi, A. ; Alqubaishi, F. ; Alotaibi, S. ; Binowayn, A. ; Alsolm, E.A. ; El Bardisy, H. ; Fawzy, M. ; Cai, F. ; Soranzo, N. ; Butterworth, A. ; COVID-19 Host Genetics Initiative ; DeCOI Host Genetics Group ; GEN-COVID Multicenter Study (Italy) ; Mount Sinai Clinical Intelligence Center ; GEN-COVID consortium (Spain) ; GenOMICC Consortium ; Japan COVID-19 Task Force ; Regeneron Genetics Center ; Geschwind, D.H. ; Arteaga, S. ; Stephens, A.E. ; Butte, M.J. ; Boutros, P.C. ; Yamaguchi, T.N. ; Tao, S. ; Eng, S. ; Sanders, T. ; Tung, P.J. ; Broudy, M.E. ; Pan, Y. ; González, A.J. ; Chavan, N. ; Johnson, R. ; Pasaniuc, B. ; Yaspan, B.L. ; Smieszek, S. ; Rivolta, C. ; Bibert, S. ; Bochud, P.Y. ; Dabrowski, M. ; Zawadzki, P. ; Sypniewski, M. ; Kaja, E. ; Chariyavilaskul, P. ; Nilaratanakul, V. ; Hirankarn, N. ; Shotelersuk, V. ; Pongpanich, M. ; Phokaew, C. ; Chetruengchai, W. ; Tokunaga, K. ; Sugiyama, M. ; Kawai, Y. ; Hasegawa, T. ; Naito, T. ; Namkoong, H. ; Edahiro, R. ; Kimura, A. ; Ogawa, S. ; Kanai, T. ; Fukunaga, K. ; Imoto, S. ; Miyano, S. ; Mangul, S. ; Abedalthagafi, M.S. ; Zeberg, H. ; Grzymski, J.J. ; Washington, N.L. ; Ossowski, S. ; Ludwig, K.U. ; Schulte, E.C. ; Riess, O. ; Moniuszko, M. ; Kwasniewski, M. ; Mbarek, H. ; Ismail, S.I. ; Verma, A. ; Goldstein, D.B. ; Kiryluk, K. ; Renieri, A. ; Richards, J.B.

Exome-wide association study to identify rare variants influencing COVID-19 outcomes: Results from the Host Genetics Initiative.

Contact

Regina Geiger

Secretary