September 11, 2024 Registrations are now open for the Munich Epigenetics Spotlight MeetingMark your Calendars for the 8th Munich Epigenetics Spotlight Meeting: October 23rd, 2024, 14h-19h.On Wednesday, October 23rd 2024, Dr. Maria Elena Torres-Padilla (Director, IES) and Dr. Robert Schneider (Director, IFE) invite fellow researchers…read more
Computational Health, AIH, August 16, 2024 The DFG awarded 1.25m Euro funding to Prof. Irmela JeremiasThe German Research Foundation (DFG) has awarded Reinhart Koselleck funding in the amount of 1.25 Mio. Euro to Prof. Irmela Jeremias, head of the Research Unit Apoptosis in Hematopoietic Stem Cells (AHS) at the Stem Cell Center, for her outstanding…read more
IES, ICB, IFE, April 18, 2024 From Single-Cell Data to Gene Networks: Evaluating Algorithms with STREAMLINEAs single-cell omic techniques continue to revolutionize our understanding of gene expression patterns, the need for robust tools to infer gene regulatory networks (GRNs) becomes increasingly urgent. In a new study, Dr. Scialdone and his team at…read more
IES, STB, April 17, 2024 The role of non-coding RNAs in Chromosome Segregation through Mechanisms Beyond the SequenceChromosome segregation, a fundamental process in cell division, ensures the precise distribution of genetic material to daughter cells. Chen et al., explore the role of non-coding RNAs contributing to the robustness of this process.read more
IES, November 17, 2023 MATAC-Seq: lifting the fog around cell to cell variabilityResearchers at the Hamperl lab from the Institute of Epigenetics and Stem Cells (IES), working alongside the Scialdone lab at the institute and Lopes lab in University of Zurich, introduce the innovative approach for accurately mapping the dynamics…read more
November 16, 2023 Mark your calendars for Munich Epigenetics Spotlight Meeting 2024: October 23rdWe are happy to announce the date for the 8th Munich Epigenetics Spotlight meeting which will happen on Wednesday, October 23rd, 2024. Stay tuned for more news!read more
IES, November 09, 2023 Unveiling the Dynamics of LAD Reorganization and Transcription in Early Embryonic DevelopmentIn a recent publication in Genes and Development, the researchers from Torres-Padilla lab (Institute of Epigenetics and Stem Cells, IES) have shed light on the intricate interplay between nuclear organization and transcriptional activity during early…read more
October 19, 2023 The afternoon of Science: Munich Epigenetics Spotlight Meeting 2023 brings epigenetics community togetherOn October 16, 2023, the Munich Epigenetics community came together for their 7th annual Epigenetics Spotlight meeting, dedicating an afternoon to explore the latest breakthroughs in the field of epigenetics. In addition to the enlightening…read more
IFE, July 31, 2023 In memory of Colyn Crane-Robinson (1935–2023)We pay tribute to the loss of a remarkable scientist, Colyn Crane-Robinson, who passed away on 5th March 2023. Throughout his lifetime, Colyn's unwavering dedication and infectious enthusiasm enriched our understanding of nucleic acid structures and…read more
IES, July 28, 2023 July recap: two new manuscripts from Torres-Padilla labIn July, the Torres-Padilla lab published two new manuscripts showcasing their latest research contributions.read more
IFE, July 14, 2023 IUBMB Focused Meeting on Integrative Omics of Nuclear Functions 2023The IUBMB Focused Meeting on Integrative Omics of Nuclear Functions co-organized by Dr. Till Bartke from the Institute of Functional Epigenetics will take place in Crete (Greece) on October 15-20, 2023.read more
IDC, VIRO, IFE, July 06, 2023 Deciphering connections between cancer metabolism, the epigenome and cellular stressIn a cross-departmental collaboration with the Institute for Diabetes and Cancer (IDC) and the Institute of Virology (Viro), researchers from the Schneider lab (Institute of Functional Epigenetics, IFE) have discovered a novel axis connecting…read more
IES, IFE, June 12, 2023 Finding needles in a haystack of single-cell data: algorithm developed by Scialdone lab helps identify rare cells in single-cell sequencing datasets.The analysis of single-cell RNA-sequencing data is a powerful tool for identifying new types of cells. However, the rarer the cells are, the more challenging it becomes to find and characterize them. This means that rare cells can often go unnoticed,…read more
IFE, February 28, 2023 Paris-Munich Epigenetics Workshop & Symposium 2023The Paris-Munich Epigenetics Workshop & Symposium organized by Dr. Till Bartke from the Institute of Functional Epigenetics will take place at the Max Planck Institute of Biochemistry in Munich on June 14-16, 2023. read more
IES, February 06, 2023 How origins of replication are organized by the cytoskeletonBefore a cell divides, the genomic content of a cell is duplicated during DNA replication. Each cell has many origins of replication (ORIs), but not all are active at the same time, and some fire earlier and some later. Combining their approach to…read more
December 27, 2022 How our genes are read at the beginning of lifeResearchers from the Institute for Epigenetics and Stem Cells at Helmholtz Munich studied RNA Polymerase II (Pol II) in early mouse embryos and shed light on transcriptional elongation during zygotic genome activation (ZGA), a key process of…read more
December 16, 2022 Call for the Summer Internship Program 2023 in Epigenetics, Stem Cells, and Artificial Intelligence is open!You are excited about understanding life? You would like to gain hands-on research experience and find out more about the daily life of scientists? The call for our SUMMER INTERNSHIP PROGRAM 2023 IN EPIGENETICS, STEM CELLS, AND ARTIFICAL…read more
IFE, November 16, 2022 Sharing = Caring? – Asymmetric RNA Segregation depends on the replicative age of cellsWhen a cell divides, the correct distribution of cellular content, such as RNAs, to daughter cells is essential. By tagging RNAs with the new diSpinach aptamer in combination with a self-made microfluidics device, researchers at the Institute of…read more
November 11, 2022 Altered expression response upon repeated gene repressionCells must continuously adjust to their environments and cope with changing temperatures, stress conditions, or resources. Particularly, if conditions change repeatedly, it might make sense for cells to adjust more effectively. A collaborative…read more
November 09, 2022 The fourth Epigenetics Retreat was a great successThe fourth epigenetics@HelmholtzMunich retreat took place on November 7th – 8th 2022 close to Lake Ammersee in Bavaria.read more
IES, IFE, November 02, 2022 Young Epigenetic Scientists at the new Science Communication lab of the Deutsches MuseumInspired by recent work from Antonio Scialdone’s group on the spatial expression of olfactory neurons, Maria Elena Torres Padilla and Robert Schneider, directors of IES and IFE respectively, teamed up with the Deutsches Museum to share our research…read more
October 25, 2022 Full house again at the 6th Munich Epigenetics Spotlight MeetingThe sixth Munich Epigenetic Spotlight meeting was held at the Stem Cell Center of Helmholtz Munich in Großhadern on Monday 24th October 2022. Keynote speakers were Eileen Furlong from EMBL, Heidelberg, and Yang Shi from the Ludwig Institute for…read more
IES, IFE, October 20, 2022 1st Helmholtz Summer School on Chromatin Biology was a great success. The first 'Helmholtz Summer School on Chromatin Biology: A hands-on-expedition', organized by the Institute of Epigenetics and Stem Cells (IES) and the Institute of Functional Epigenetics (IFE) in collaboration with Abcam, took place on Campus from…read more
IFE, October 13, 2022 Summer Intern Ecaterina Radzichevici contributes to publication about the structural maintenance of chromosomeSince 2016, the annual Summer Internship Program in Epigenetics, Stem Cells, and Artificial Intelligence gives international students the opportunity to work alongside world-leading scientists on original research. Under the supervision of Kurt…read more
Stem Cells, IES, August 30, 2022 From idea to implementation – Anna Dumitriu ran a workshop about her artwork “The Cellular Reprogramming Necklace”During her stay in August 2022, Anna Dumitriu ran a workshop with researchers at the Institute for Epigenetics and Stem Cells to share her thoughts and experiences of the creative process underlying her artwork “The Cellular Reprogramming Necklace”. read more
Stem Cells, IES, August 09, 2022 What stands behind the message sent by histone PTMs?Over the last 60 years, research has shed light on histone PTMs and their role in all DNA-templated processes. In the last decade, novel methodologies, such as genome-wide sequencing approaches, have paved the way toward understanding how their…read more
Stem Cells, IES, April 08, 2022 Communication is the key, also between cells.Just as we use Google Maps, cells rely on gradient sensing of signal molecules to reach their destination. However, in their case, the destination is the source of the attractant and not the restaurant of choice. Using mathematical models,…read more
Stem Cells, IES, April 02, 2022 Helmholtz Munich is part of the new Innovative Training Network “RepliFate”The EU funds a new Innovative Training Network (ITN) in the field of DNA replication, cell fate, and cancer with Helmholtz Munich as a beneficiary. The ITN will investigate the role of DNA replication as a determinant of cell fate and cancer.read more
Stem Cells, IES, March 22, 2022 Always follow your nose – On the trail of the anatomical logic of smellThe sense of smell is essential for almost all animals. It helps find food, detect dangers, and distinguish between friends and enemies. As the saying goes: You really get up my nose. Research carried out at Helmholtz Munich has shown that…read more
Stem Cells, IES, March 18, 2022 EpIC - EpiGene3Sys meets INC_Spain to ChromDesign the GenomeFrom October 17th to 20th October 2022, the conference "EpIC - EpiGene3Sys meets INC_Spain to ChromDesign the Genome" will take place in Granada, Spain. The registration will open soon.read more
Stem Cells, IES, March 07, 2022 Changing the speed of DNA replication - a new way to improve the cellular reprogramming efficiencyReversing injury or disease is a major objective in research towards regenerative medicine. Replacing sick or damaged cells with healthy cells in order to repair damaged tissue is one of the most impactful strategies towards that goal. For that, a…read more
Stem Cells, IES, February 02, 2022 Summer School on Chromatin Biology: A hands-on expeditionWe are delighted to announce the launch of the "1st Helmholtz Summer School on Chromatin Biology: A hands-on expedition", which will take place at the Neuherberg Campus of Helmholtz Munich, from August 15-26, 2022.read more
Stem Cells, IES, January 03, 2022 Eva Hörmanseder receives DFG grant to investigate cell-fate changes during reprogrammingThe possibility to generate any cell type from a differentiated, somatic cell can advance cell-replacement therapies and holds great promises to regenerative medicine. Therefore, understanding the molecular mechanisms underlying cell-fate changes…read more
Stem Cells, IES, November 18, 2021 A milestone for developmental biology - Scientists publish the first single-transcriptome of a human gastrulation embryoFor the first time, scientists based at Helmholtz Zentrum München and the University of Oxford were able to shed light on one of the most critical stages of human embryonic development (gastrulation). Their findings will drive future studies to…read more
Stem Cells, IES, July 22, 2021 The prestigious Academia Europeae has elected Maria-Elena Torres-Padilla and Robert Schneider as membersAfter a rigorous peer-review process, the board of trustees of Academia Europeae, the pan-European academy of science, humanities, and letters, has elected our Stem Cell expert Prof. Maria-Elena Torres-Padilla. This is a recognition of her standing…read more
Stem Cells, IES, July 21, 2021 Mitochondrial defects characterize 'loser' cells in cell competitionThe work of the Scialdone Lab at the Helmholtz Zentrum München and the Rodriguez at the Imperial College elucidates that differences in mitochondrial activity are key determinants for cellular fitness in various contexts, where endogenous cell…read more