Cell Engineering
Stiel Lab
Imaging is our window into the processes of life – we bioengineer genetically encoded protein-based tools for optical imaging such as optoacoustics and super resolution microscopy.
Stiel Lab
Imaging is our window into the processes of life – we bioengineer genetically encoded protein-based tools for optical imaging such as optoacoustics and super resolution microscopy.
About our research group
The Cell Engineering group is devoted to the development of novel reporters and sensors for Optoacoustic (OA) imaging and other innovative imaging methods like super-resolution fluorescence microscopy. Our main focus is on genetically encoded contrast agents since only such agents allow longitudinal and unperturbed imaging in research animal to truly understand biology and diseases contexts.
To develop novel genetically encoded tools we use molecular engineering concepts that incorporate knowledge from photo-physical studies, protein structures and computational protein design and combine those insights with efficient screening concepts to identify novel reporters or sensors for the next pressing questions in whole animal imaging.
Our Researchers
Fields of Work and Expertise
Label and Sensor EngineeringFunctional Understanding (Structural and Photophysically)Highthroughput Screening Techniques for Directed Evolution