Group Leader Fluorescence Imaging
Dimitris Gorpas, PhD
“Fluorescence Molecular Imaging, through its “red-flag” operation, enables earlier, faster, and personalized disease detection and surgical guidance.”
CV
Dr. Dimitris Gorpas studied Electrical and Computer Engineering in the Department of Electrical and Computer Engineering at the Technical University of Athens, Greece. After his graduation, he obtained a Ph.D. in Engineering from the same institution. He went on to work as a postdoctoral research fellow to the Information Technologies Institute, Centre for Research and Technology, Hellas, Thessaloniki, Greece. In 2013, he moved to the Department of Biomedical Engineering at the University of California, Davis as a postdoctoral research employee.
Since 2016, he is leading the Fluorescence Imaging group at the Chair of Biological Imaging and Center for Translational Cancer Research (TranslaTUM) of the Technical University of Munich, as well as the affiliated Institute for Biological and Medical Imaging at the Helmholtz Zentrum München. His scientific interests include the development of medical intraoperative and endoscopic imaging systems, their clinical validation, and surgical guidance through optical measurements. The aim of this research is to improve understanding of optical properties of tissue and their variation in relation to structural, molecular, and biochemical or functional parameters. The ultimate goal is the development of comprehensive imaging technologies to provide physicians innovative tools for diagnostic and therapeutic purposes.
Fields of Work and Expertise
Fluorescence Imaging Clinical Translation Medical Imaging / Photonics
Standardization Image and Video Processing Computer/Robotic Vision
Professional Background
Group Leader, Institute of Biological and Medical Imaging, Helmholtz Munich, Munich, Germany
Group Leader, Institute of Biological and Medical Imaging, Helmholtz Munich, Munich, Germany (01/17-present / Permanent Contract), and Chair of Biological Imaging, Technical University of Munich, Munich, Germany (01/16-12/16).
Postdoctoral Research Employee, Department of Biomedical Engineering, University of California - Davis, Davis, California, USA.
Postdoctoral Research Fellow, Information Technologies Institute (ITI), Centre for Research and Technology, Hellas (CERTH), Thessaloniki, Greece.
Mandatory military service in Greece.
Ph.D. in Engineering, School of Electrical and Computer Engineering, National Technical University of Athens, Athens, Greece.
Diploma in Electrical and Computer Engineering, School of Electrical and Computer Engineering, National Technical University of Athens, Athens, Greece.
Honors and Awards
- Recipient of special payment for outstanding scientific performance in 2018, Helmholtz Munich, Munich, Germany. 2019
- Award for "Excellence in Leadership and Grantsmanship", Institute of Biological and Medical Imaging, Helmholtz Munich, Munich, Germany. 2018
- Institute of Communication and Computer Systems (ICCS) scholarship for PhD students, National Technical University of Athens, Athens, Greece. 2009
- International SPIE Scholarship in Optical Science and Engineering.03/08–08/08 Institute of Communication and Computer Systems (ICCS) scholarship for PhD students, National Technical University of Athens, Athens, Greece. 2009
- Institute of Communication and Computer Systems (ICCS) scholarship for PhD students, National Technical University of Athens, Athens, Greece. 2008
- "Progress of Science" awards, Thomaidio Foundation, National Technical University of Athens, Greece. One of my publications (4 in total) was awarded each year. 2005-2008
- National Technical University of Athens scholarship for PhD students. 2004-2008
- Institute of Communication and Computer Systems (ICCS) scholarship for PhD students, National Technical University of Athens, Athens, Greece. 2003-2004
Publications
Kriukova, E. ; Mazurenka, M. ; Marcazzan, S. ; Tschurtschenthaler, M. ; Puppels, G.J. ; Glasl, S. ; Saur, D. ; Jesinghaus, M. ; Pouliou, M. ; Agelopoulos, M. ; Klinakis, A. ; Quante, M. ; Ripoll, J. ; Ntziachristos, V. ; Gorpas, D.
Probing field cancerization in the gastrointestinal tract using a hybrid raman and partial wave spectroscopy microscope.Gorpas, D. ; Ntziachristos, V.
Multi-parametric standards for performance assessment and quality control of fluorescence molecular imaging and endoscopy systems.Keizers, B. ; Nijboer, T.S. ; van der Fels, C.A.M. ; van den Heuvel, M.C. ; van Dam, G.M. ; Kruijff, S. ; Jan de Jong, I. ; Witjes, M.J.H. ; Voskuil, F.J. ; Gorpas, D. ; Browne, W.R. ; van der Zaag, P.J.
Systematic comparison of fluorescence imaging in the near-infrared and shortwave-infrared spectral range using clinical tumor samples containing cetuximab-IRDye800CW.Kriukova, E. ; LaRochelle, E. ; Pfefer, T.J. ; Kanniyappan, U. ; Gioux, S. ; Pogue, B.W. ; Ntziachristos, V. ; Gorpas, D.
Impact of signal-to-noise ratio and contrast definition on the sensitivity assessment and benchmarking of fluorescence molecular imaging systems.Huang, Y.J. ; Rieder, J. ; Tan, K.V. ; Tenditnaya, A. ; Vojnovic, B. ; Gorpas, D. ; Quante, M. ; Vallis, K.A.
Targeting c-MET for endoscopic detection of dysplastic lesions within Barrett's esophagus using EMI-137 fluorescence imaging.Kriukova, E. ; Mazurenka, M. ; Marcazzan, S. ; Glasl, S. ; Quante, M. ; Saur, D. ; Tschurtschenthaler, M. ; Puppels, G.J. ; Gorpas, D. ; Ntziachristos, V.
Hybrid Raman and partial wave spectroscopy microscope for the characterization of molecular and structural alterations in tissue.Rauschendorfer, P. ; Lenz, T. ; Nicol, P. ; Wild, L. ; Beele, A. ; Sabic, E. ; Klosterman, G.R. ; Laugwitz, K.L. ; Jaffer, F.A. ; Gorpas, D. ; Joner, M. ; Ntziachristos, V.
Intravascular ICG-enhanced NIRF-IVUS imaging to assess progressive atherosclerotic lesions in excised human coronary arteries.Tenditnaya, A. ; Gabriels, R.Y. ; Hooghiemstra, W.T.R. ; Klemm, U. ; Nagengast, W.B. ; Ntziachristos, V. ; Gorpas, D.
Performance assessment and quality control of fluorescence molecular endoscopy with a multi-parametric rigid standard.Marcazzan, S. ; Braz Carvalho, M.J. ; Nguyen, N.T. ; Strangmann, J. ; Slotta-Huspenina, J. ; Tenditnaya, A. ; Tschurtschenthaler, M. ; Rieder, J. ; Proaño-Vasco, A. ; Ntziachristos, V. ; Steiger, K. ; Gorpas, D. ; Quante, M. ; Kossatz, S.
PARP1-targeted fluorescence molecular endoscopy as novel tool for early detection of esophageal dysplasia and adenocarcinoma.Gabriels, R.Y. ; van Heijst, L.E. ; Hooghiemstra, W.T.R. ; van der Waaij, A.M. ; Kats-Ugurlu, G. ; Karrenbeld, A. ; Robinson, D.J. ; Tenditnaya, A. ; Ntziachristos, V. ; Gorpas, D. ; Nagengast, W.B.
Detection of early esophageal neoplastic barrett lesions with quantified fluorescence molecular endoscopy using Cetuximab-800CW.