Dr. Dimitris Gorpas

Group Leader Fluorescence Imaging

Fluorescence Molecular Imaging, through its “red-flag” operation, enables earlier, faster, and personalized disease detection and surgical guidance.

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Dr. Dimitris Gorpas studied Electrical and Computer Engineering in the Department of Electrical and Computer Engineering at the Technical University of Athens, Greece. After his graduation, he obtained a Ph.D. in Engineering from the same institution. He went on to work as a postdoctoral research fellow to the Information Technologies Institute, Centre for Research and Technology, Hellas, Thessaloniki, Greece. In 2013, he moved to the Department of Biomedical Engineering at the University of California, Davis as a postdoctoral research employee. Since 2016, he is leading the Fluorescence Imaging group at the Chair of Biological Imaging and Center for Translational Cancer Research (TranslaTUM) of the Technical University of Munich, as well as the affiliated Institute for Biological and Medical Imaging at the Helmholtz Zentrum München. His scientific interests include the development of medical intraoperative and endoscopic imaging systems, their clinical validation, and surgical guidance through optical measurements. The aim of this research is to improve understanding of optical properties of tissue and their variation in relation to structural, molecular, and biochemical or functional parameters. The ultimate goal is the development of comprehensive imaging technologies to provide physicians innovative tools for diagnostic and therapeutic purposes.

Fields of Work and Expertise

Fluorescence Molecular ImagingMedical ImagingPhotonicsClinical TranslationStandardizationImage and Video Processing Computer/Robotic Vision

Personal Background

2016 - present

Group Leader, Institute of Biological and Medical Imaging, Helmholtz Munich, Munich, Germany

Group Leader, Institute of Biological and Medical Imaging, Helmholtz Munich, Munich, Germany (01/17-present / Permanent Contract), and Chair of Biological Imaging, Technical University of Munich, Munich, Germany (01/16-12/16).

2013-2015

Postdoctoral Research Employee, Department of Biomedical Engineering, University of California - Davis, Davis, California, USA.

2012-2013

Postdoctoral Research Fellow, Information Technologies Institute (ITI), Centre for Research and Technology, Hellas (CERTH), Thessaloniki, Greece.

11/10-08/11

Mandatory military service in Greece.

2003-2010

Ph.D. in Engineering, School of Electrical and Computer Engineering, National Technical University of Athens, Athens, Greece.

1998-2003

Diploma in Electrical and Computer Engineering, School of Electrical and Computer Engineering, National Technical University of Athens, Athens, Greece.

Honors and Awards

Recipient of special payment for outstanding scientific performance in 2018, Helmholtz Munich, Munich, Germany.
2019
Award for "Excellence in Leadership and Grantsmanship", Institute of Biological and Medical Imaging, Helmholtz Munich, Munich, Germany.
2018
Institute of Communication and Computer Systems (ICCS) scholarship for PhD students, National Technical University of Athens, Athens, Greece.
2009
International SPIE Scholarship in Optical Science and Engineering.03/08–08/08 Institute of Communication and Computer Systems (ICCS) scholarship for PhD students, National Technical University of Athens, Athens, Greece.
2009
Institute of Communication and Computer Systems (ICCS) scholarship for PhD students, National Technical University of Athens, Athens, Greece.
2008
"Progress of Science" awards, Thomaidio Foundation, National Technical University of Athens, Greece. One of my publications (4 in total) was awarded each year.
2005-2008
National Technical University of Athens scholarship for PhD students.
2004-2008
Institute of Communication and Computer Systems (ICCS) scholarship for PhD students, National Technical University of Athens, Athens, Greece.
2003-2004

Publications

Systematic comparison of fluorescence imaging in the near-infrared and shortwave-infrared spectral range using clinical tumor samples containing cetuximab-IRDye800CW.

2025 Scientific Article in Journal of Biomedical Optics

Kriukova, E. ; LaRochelle, E. ; Pfefer, T.J. ; Kanniyappan, U. ; Gioux, S. ; Pogue, B.W. ; Ntziachristos, V. ; Gorpas, D.

Impact of signal-to-noise ratio and contrast definition on the sensitivity assessment and benchmarking of fluorescence molecular imaging systems.

2024 Scientific Article in Clinical Cancer Research

Huang, Y.J. ; Rieder, J. ; Tan, K.V. ; Tenditnaya, A. ; Vojnovic, B. ; Gorpas, D. ; Quante, M. ; Vallis, K.A.

Targeting c-MET for endoscopic detection of dysplastic lesions within Barrett's esophagus using EMI-137 fluorescence imaging.

2024 Scientific Article in Journal of Biophotonics

Kriukova, E. ; Mazurenka, M. ; Marcazzan, S. ; Glasl, S. ; Quante, M. ; Saur, D. ; Tschurtschenthaler, M. ; Puppels, G.J. ; Gorpas, D. ; Ntziachristos, V.

Hybrid Raman and partial wave spectroscopy microscope for the characterization of molecular and structural alterations in tissue.

2024 Scientific Article in NPJ Cardiovascular Health

Rauschendorfer, P. ; Lenz, T. ; Nicol, P. ; Wild, L. ; Beele, A. ; Sabic, E. ; Klosterman, G.R. ; Laugwitz, K.L. ; Jaffer, F.A. ; Gorpas, D. ; Joner, M. ; Ntziachristos, V.

Intravascular ICG-enhanced NIRF-IVUS imaging to assess progressive atherosclerotic lesions in excised human coronary arteries.

2024 Scientific Article in IEEE Transactions on Medical Imaging

Tenditnaya, A. ; Gabriels, R.Y. ; Hooghiemstra, W.T.R. ; Klemm, U. ; Nagengast, W.B. ; Ntziachristos, V. ; Gorpas, D.

Performance assessment and quality control of fluorescence molecular endoscopy with a multi-parametric rigid standard.

2024 Scientific Article in Journal of Experimental and Clinical Cancer Research

Marcazzan, S. ; Braz Carvalho, M.J. ; Nguyen, N.T. ; Strangmann, J. ; Slotta-Huspenina, J. ; Tenditnaya, A. ; Tschurtschenthaler, M. ; Rieder, J. ; Proaño-Vasco, A. ; Ntziachristos, V. ; Steiger, K. ; Gorpas, D. ; Quante, M. ; Kossatz, S.

PARP1-targeted fluorescence molecular endoscopy as novel tool for early detection of esophageal dysplasia and adenocarcinoma.

2023 Scientific Article in Journal of Nuclear Medicine

Gabriels, R.Y. ; van Heijst, L.E. ; Hooghiemstra, W.T.R. ; van der Waaij, A.M. ; Kats-Ugurlu, G. ; Karrenbeld, A. ; Robinson, D.J. ; Tenditnaya, A. ; Ntziachristos, V. ; Gorpas, D. ; Nagengast, W.B.

Detection of early esophageal neoplastic barrett lesions with quantified fluorescence molecular endoscopy using Cetuximab-800CW.

2023 Scientific Article in Biomedical Optics Express

Arias, A. ; Anastasopoulou, M. ; Gorpas, D. ; Ntziachristos, V.

Using reflectometry to minimize the dependence of fluorescence intensity on optical absorption and scattering.

2023 Scientific Article in Journal of Biomedical Optics

Rauschendorfer, P. ; Wissmeyer, G. ; Jaffer, F.A. ; Gorpas, D. ; Ntziachristos, V.

Accounting for blood attenuation in intravascular near-infrared fluorescence-ultrasound imaging using a fluorophore-coated guidewire.

Network

• Member of the European Society for Molecular Imaging (ESMI).
• Member of the Institute of Electrical and Electronics Engineers (IEEE).
• Member of the IEEE Engineering in Medicine and Biology Society.
• Member of the Society of Photo-Optical Instrumentation Engineers (SPIE).
• Member of Optica (formely OSA).
• Member of the Institute for Systems and Technologies of Information, Control and Communication (INSTICC).

Dimitris Gorpas, PhD

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