Helmholtz Diabetes Center Institute of Diabetes and Regeneration Research

In 2021, a research team led by Prof. Heiko Lickert from Helmholtz Munich discovered the insulin-inhibitory receptor "Inceptor" and its role as a suppressor of the insulin signaling pathway. Now, the researchers have unlocked another, even more…

Researchers at Helmholtz Munich have received an award from Breakthrough T1D, a leading global type 1 diabetes (T1D) research and advocacy organization, to fund a new diabetes research project. The project will leverage advanced artificial…

This summer and fall, Helmholtz Munich will participate in three major community events in Munich: the FORSCHA, the OBEN OHNE Festival, and the Maus Türöffner-Tag. These engagements highlight Helmholtz Munich’s commitment to fostering public interest…

On June 12, 2024, the National Strategy for Gene and Cell Therapies was unveiled at the Futurium in Berlin.

Congratulations to Eunike Setyono, Melis Akgün Canan and Tobias Greisle for winning the DZD Outstanding Young Investigator Award 2023!

Research targeting the insulin-inhibitory receptor, called inceptor, unveils promising avenues for beta cell protection, offering hope for causal diabetes therapy. A novel study in mice with diet-induced obesity demonstrates that the knock-out of…

Sex-Specific Research

Our organs do a remarkable job day in and day out, without ourselves even having to think about it. Our body has its own ventilation system, a clearance system for toxins, and a system to balance energy homeostasis. But what if one of these systems…

A collaborative endeavor between computer scientists and diabetes researchers at Helmholtz Munich has yielded novel insights into the mechanisms underlying type 1 and type 2 diabetes. This collaboration has resulted in the creation of the first mouse…

Helmholtz Munich researchers receive 2.25 Mio US Dollar JDRF Grant 

With a 2.25 million US dollar grant provided by the Juvenile Diabetes Research Foundation (JDRF), Prof. Matthias Hebrok, Prof. Heiko Lickert, and Prof. Carolin Daniel from the…

Type 2 diabetes disease progression and successful intervention depend on individual’s unique clinical, genetic, genomic, and environmental information partly represented by gene expression patterns. An international team of researchers around…

Researchers at Helmholtz Munich are working toward a world without diabetes. They are not doing so alone, but with a network of organizations, hospitals, and pharmaceutical companies. Their goal is to use experts’ knowledge to create something new:…

Two newly acquired ERC Advanced Grants support the cutting-edge research of Munich Helmholtz scientists Heiko Lickert and Fabian Theis. The researchers are international stars in the fields of diabetes and artificial intelligence. The funding will…

The 100th anniversary of the discovery of insulin is a milestone in diabetes research and insulin continues to be a lifesaver for many people. At the same time, the International Diabetes Federation predicts a rise in the number of diabetes cases to…

Scientists from Helmholtz Zentrum München revise the current textbook knowledge about gastrulation, the formation of the basic body plan during embryonic development. Their study in mice has implications for cell replacement strategies and cancer…

Researchers have discovered a novel and druggable insulin inhibitory receptor, named inceptor. The latest study from Helmholtz Zentrum München, the Technical University of Munich and the German Center for Diabetes Research is a significant milestone…

The gut plays a central role in the regulation of the body’s metabolism and its dysfunction is associated with a variety of diseases, such as obesity, diabetes, colitis and colorectal cancer that affect millions of people worldwide. Targeting…

The loss of insulin-secreting beta cells by autoimmune destruction leads to type 1 diabetes. Clinical islet cell transplantation has the potential to cure diabetes, but donor pancreases are rare. In a new study, a group of researchers developed an…

The loss of the identity of insulin-secreting beta cells in the islet of Langerhans, a process also called beta cell dedifferentiation, has been proposed to be a main reason for the development of diabetes. If and how dedifferentiated beta cells can…