Stem Cell Center
Stem cells are unique in their capacity to proliferate and replacing cells – often life-long. However, many adult organs, such as the brain or the pancreas, have no or few stem cells. The Department’s mission builds on our pioneer approach to reprogram local cells towards the lost cell type identity in such organs and on our pioneer discoveries on epigenetic mechanisms of reprogramming. The key proteins that enable such fate conversion have been all identified for their role during development, when all relevant cell types are generated. Our Department therefore combines in a world-wide unique combination expertise in stem cells, developmental mechanisms of fate specification and plasticity including a strong epigenetic expertise with injury models and direct reprogramming.
Stem Cell Center
Replacing lost or damaged cells is the cornerstone of regenerative medicine. To achieve this, we need to understand not only how cells acquire their specific identity but also how cell plasticity is regulated. Helmholtz Munich’s Stem Cell Center is unique worldwide in combining leading expertise in cell plasticity, epigenetics, and direct reprogramming.
Our Stem Cell Experts
