Helmholtz Diabetes Center Institute of Experimental Genetics
The Institute of Experimental Genetics (IEG) aims to further the understanding of mechanisms underlying human diseases' etiology. Metabolic diseases with a focus on diabetes are key areas of research. Experimental set-ups are centered on the mouse as a pre-clinical model organism with direct translation of results to humans. Besides studying the effects of genotypes, the institute identifies and characterizes environmental and epigenetic factors and the mechanisms by which these act on the etiology of diseases.
The Institute of Experimental Genetics (IEG) aims to further the understanding of mechanisms underlying human diseases' etiology. Metabolic diseases with a focus on diabetes are key areas of research. Experimental set-ups are centered on the mouse as a pre-clinical model organism with direct translation of results to humans. Besides studying the effects of genotypes, the institute identifies and characterizes environmental and epigenetic factors and the mechanisms by which these act on the etiology of diseases.
Selected Publications of the IEG
Read more2025 Scientific Article in Investigative Ophthalmology & Visual Science, IOVS
Systematic ocular phenotyping of knockout mouse lines identifies genes associated with age-related corneal dystrophies.
2025 Scientific Article in Molecular Metabolism
Pervasive glycative stress links metabolic imbalance and muscle atrophy in early-onset Parkinson's disease.
2025 Scandinavian journal of medicine & science in sports
The metabolic fingerprint of cardiorespiratory fitness (vol 35, e70034, 2025).
2025 Scientific Article in Reproduction
Towards a kingdom of reproductive life - the core sperm proteome.
2025 Editorial in Journal of Steroid Biochemistry and Molecular Biology, The
Facing challenges in modern steroid research.
2025 Scientific Article in STAR Protocols