Helmholtz Diabetes Center Institute of Experimental Genetics
The Institute of Experimental Genetics (IEG) aims to further the understanding of mechanisms underlying human diseases' etiology. Metabolic diseases with a focus on diabetes are key areas of research. Experimental set-ups are centered on the mouse as a pre-clinical model organism with direct translation of results to humans. Besides studying the effects of genotypes, the institute identifies and characterizes environmental and epigenetic factors and the mechanisms by which these act on the etiology of diseases.
The Institute of Experimental Genetics (IEG) aims to further the understanding of mechanisms underlying human diseases' etiology. Metabolic diseases with a focus on diabetes are key areas of research. Experimental set-ups are centered on the mouse as a pre-clinical model organism with direct translation of results to humans. Besides studying the effects of genotypes, the institute identifies and characterizes environmental and epigenetic factors and the mechanisms by which these act on the etiology of diseases.
Selected Publications of the IEG
Read more2025 Scientific Article in Acta Physiologica
Hypotaurine reduces glucose-mediated vascular calcification.
2025 Scientific Article in Investigative Ophthalmology & Visual Science, IOVS
Ocular phenotyping of knockout mice identifies genes associated with late adult retinal phenotypes.
2025 Scientific Article in Analytical Chemistry
Structure elucidation for MALDI mass spectrometry imaging using infrared ion spectroscopy.
2025 Scientific Article in Molecular Metabolism
Sex differences in resting skeletal muscle and the acute and long-term response to endurance exercise in individuals with overweight and obesity.
2025 Editorial in Journal of Steroid Biochemistry and Molecular Biology, The
Frontiers in Steroid Research: Steroid Congress 2023.
2025 Scientific Article in ACS Chemical Biology