Helmholtz Munich

Medicine doctor touching electronic medical record on tablet. DNA

The primary research goal of the Institute of Diabetes Research and Metabolic Diseases is the individualized prediction of diabetes risk and diabetes prevention and its personalized therapy.

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Our News

Senior woman checking blood sugar level at home

IDM, November 23, 2023

In the latest episode of DocFischer, researchers at the DZD explain what lies behind prediabetes and whether lifestyle changes can help.

IDM, November 21, 2023

Many people suffer from type II diabetes, sometimes without even knowing it. Prof. Andreas Birkenfeld explains why exercise and the right diet are particularly important.

Woman using glucometer on blue background, top view

IDM, October 20, 2023

The TV program BR Gesundheit ('Health') on October 10 was dedicated to the topic "Diabetes - Fight Against Diabetes". In the various reports, researchers of the German Center for Diabetes Research (DZD) were interviewed as experts. For example, on…

Obesity overweight diabetes fitness abdomen adult background

IDM, October 20, 2023

Prediabetes is a preliminary stage of type 2 diabetes with an increased risk of heart attack, kidney and eye diseases and various types of cancer. Scientists from the German Center for Diabetes Research (DZD) show that remission of prediabetes is…

IDM, September 22, 2023

The sensitivity of the brain to insulin plays a crucial role in regulating whole-body insulin sensitivity during the menstrual cycle, as a recent paper by Martin Heni, Stephanie Kullmann and colleagues published in Nature Metabolism suggests.

IDM, August 02, 2023

In its "Thesencheck" (Theses Check) video series, the University of Tübingen has now taken up the topic of obesity. Watch now the full video on YouTube.

Diabetes concept with insulin, syringe, vials, pills, and stethoscope.

IDM, May 05, 2023

Lean, metabolically unhealthy, people have a risk of cardiovascular disease that is higher than the risk observed in obese, metabolically healthy people. Recently, novel cluster analyses also identified a large heterogeneity in the risk of type 2…

IDM, April 03, 2023

Three young scientists of the IDM can count themselves among the winners of last years DZD Award. The award ceremony took place during the 26th DZD Workshop hosted in Tübingen.

IDM, January 16, 2023

IDM, January 12, 2023

In a highly competitive procedure, the Group Metabolic Imaging at the IDM was approved by the DFG for 3 years of funding.

Diabetes Kongress 2022 | 25. Mai - 28. Mai 2022 | Berlin

Awards & Grants, Diabetes, IDM, June 02, 2022

Helmholtz Munich scientist Stephanie Kullmann is awarded this year's Ferdinand Bertram Award of the German Diabetes Society (DDG). With this award, the DDG honors her research on the role of central nervous processes in the prevention and treatment…

IDM, June 01, 2022

In a highly competitive procedure, 2 Research Training Groups in Tübingen were approved by the DFG for 5 years of funding.

Male Patient Having Consultation With Doctor In Office

Fritsche Lab

Stefan Lab

Weigert Lab

Preissl Lab

Birkenfeld Lab

Clinical study center

The clinical study center manages all clinical studies of the IDM according to the regulations of the German pharmaceutical law (Arzneimittelgesetz-AMG) and Medical Associations Professional Code of Conduct (Berufsordnung, BO).

Female physician listening to her patient during consultation

Islet Facility

Our scientific focus is on beta cell function and failure: the role and molecular mechanisms of fat overload and FFA signaling.

Other research topics include cross-organ conversations: interactions of islet cells with liver - adipose tissue - brain.

Clinical Chemistry Lab

The DZD Clinical Chemistry lab is the central analytical platform for metabolism-related biomarkers in multicenter studies of the DZD.

Ongoing trial

Ongoing trial

Ongoing study

Ongoing study

Arvid Sandforth, Reiner Jumpertz von Schwartzenberg [...], Andreas L Birkenfeld.

Mechanisms of weight loss-induced remission in people with prediabetes: a post-hoc analysis of the randomised, controlled, multicentre Prediabetes Lifestyle Intervention Study (PLIS)

2023 Nature Metabolism

Julia Hummel, Charlotte Benkendorff, Louise Fritsche, Katsiaryna Prystupa, Andreas Vosseler, Sofiya Gancheva, Sandra Trenkamp, Andreas L. Birkenfeld, Hubert Preissl, Michael Roden, Hans-Ulrich Häring, Andreas Fritsche, Andreas Peter, Robert Wagner, Stephanie Kullmann & Martin Heni

Brain insulin action on peripheral insulin sensitivity in women depends on menstrual cycle phase

2023 Diabetes

Robert Wagner, Martin Heni, Konstantinos Kantartzis, Arvid Sandforth, Jürgen Machann, Fritz Schick, Andreas Peter, Louise Fritsche, Julia Szendrödi, Andreas F H Pfeiffer, Annette Schürmann, Matthias Blüher, Hans Hauner, Jochen Seissler, Stefan Bornstein, Michael Roden, Norbert Stefan, Andreas L Birkenfeld, Morris F White, Hans-Ulrich Häring, Andreas Fritsche

Lower Hepatic Fat Is Associated With Improved Insulin Secretion in a High-Risk Prediabetes Subphenotype During Lifestyle Intervention

2023 International Journal of Obesity

Dreher SI, Irmler M, Pivovarova-Ramich O, Kessler K, Jürchott K, Sticht C, Fritsche L, Schneeweiss P, Machann J, Pfeiffer AFH, Hrabě de Angelis M, Beckers B, Birkenfeld AL, Peter A, Niess AM, Weigert C & Moller A

Acute and long-term exercise adaptation of adipose tissue and skeletal muscle in humans: a matched transcriptomics approach after 8-week training-intervention.

2022 Biology Open

Szabo R, Ward JM, Artunc F, Bugge TH

EPCAM and TROP2 share role in claudin stabilization and development of intestinal and extraintestinal epithelia in mice.

2022 Current Medicinal Chemistry

Wörn M, Kalbacher H, Artunc F

Proteolytic activity against the distal polybasic tract of the gamma subunit of the epithelial sodium channel ENaC in nephrotic urine.

2022 Diabetes, Obesity and Metabolism

Hummel J, Machann J, Dannecker C, Kullmann S, Birkenfeld AL, Häring HU, Peter A, Fritsche A, Wagner R, Heni M

Eight weeks of empagliflozin does not affect pancreatic fat content and insulin secretion in people with prediabetes.

2022 Diabetologie und Stoffwechsel

Schuett K, Aberle J, Bauersachs J, Birkenfeld AL, Frantz S, Ganz M, Jacob S, Kellerer M, Leschke M, Liebetrau C, Marx N, Mueller-Wieland D, Raake P, Schulze PC, Tschoepe D, von Haehling S, Zelniker TA, Forst T

Positionspapier Herzinsuffizienz und Diabetes.

2022 PLoS ONE

Potzel A, Gar C, Banning F, Sacco V, Fritsche A, Fritsche L, Müssig K, Dauben L, Seissler J, Lechner A

A novel smartphone app to change risk behaviors of women after gestational diabetes: A randomized controlled trial.

2022 International Journal of Obesity

Schneider E, Spetter MS, Martin E, Sapey E, Yip KP, Manolopoulos KN, Tahrani AA, Thomas JM, Lee M, Hallschmid M, Rotshtein P, Dourish CT, Higgs S

The effect of intranasal insulin on appetite and mood in women with and without obesity: An experimental medicine study.

Institute of Diabetes Research and Metabolic Diseases (IDM)

The primary research goal of the Institute of Diabetes Research and Metabolic Diseases is the individualized prediction of diabetes risk and diabetes prevention and its personalized therapy.

The primary research goal of the Institute of Diabetes Research and Metabolic Diseases is the individualized prediction of diabetes risk and diabetes prevention and its personalized therapy.

Our News

Prediabetes - what's behind it and does a lifestyle change help?

Kaffee oder Tee: Type II diabetes - what you should know

BR 'Health': 'Diabetes · Fight Against Diabetes' with DZD Researchers

Abdominal Fat Plays Important Role in Remission of Prediabetes

Menstrual cycle phase may affect insulin sensitivity

THESIS CHECK: "THESE 10 PRECONCEPTIONS ABOUT OBESITY AND THE WEIGHT LOSS INJECTION ARE QUESTIONABLE"

Metabolic health and cardiometabolic risk clusters help to remodel the prediction and therapy of cardiometabolic diseases

Three young scientists of the IDM received a DZD Award 2022

Prof. Dr. Andreas Birkenfeld talks about the effects of a lipometabolic disorder in "DOC Fischer".

IDM partners in the Scientific Priority Program “Radiomics: Next Generation of Biomedical Imaging”

Stephanie Kullmann Receives the Ferdinand Bertram Award 2022

IDM partners in two new graduate programs

Our Research Groups

Prevention

Pathophysiology of Prediabetes

Molecular Diabetology

Metabolic Neuroimaging

Translational Diabetology

Our Core Facilities

Clinical study center

Islet Facility

Clinical Chemistry Lab

Clinical Trials & Cohort Studies

German Study of gestational diabetes (PREG Study)

Dopamine Genetics

Intermittent Fasting to Improve Insulin Secretion (IFIS)

TUEDID study

Prediabetes Lifestyle Intervention Study Follow Up (PLIS FU)

Principal Investigators at the IDM

Prof. Dr. Andreas Birkenfeld

Dr. Estela Lorza-Gil

Prof. Dr. Andreas Fritsche

Prof. Dr. Hubert Preissl

Prof. Dr. Stephanie Kullmann

Dr. Gencer Sancar

Prof. Dr. Norbert Stefan

Dr. Julia Sbierski-Kind

Prof. Dr. Dr. Fritz Schick

Prof. Dr. Reiner Jumpertz-von Schwartzenberg

Prof. Dr. Cora Weigert

PD Dr. Jürgen Machann

Prof. Dr. Ferruh Artunc

Prof. Dr. Andreas Peter

Prof. Dr. Dorothea Siegel-Axel

Prof. Dr. Rainer Lehmann

PD Dr. Felicia Gerst

Recent Publications

Networks and Affiliations

German Center for Diabetes Research

Technical University of Munich

diabinfo

Research school for diabetes

Universitätsklinikum Tübingen

Universität Tübingen

Südwestdeutsches Diabeteszentrum

Contact

Ingrid Rösch

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