Helmholtz Diabetes Center
Helmholtz Institute for Metabolic, Obesity, and Vascular Research
The Helmholtz Institute for Metabolic, Obesity, and Vascular Research (Helmholtz-Institut für Metabolismus-, Adipositas- und Gefäßforschung, HI-MAG) in Leipzig investigates molecular mechanisms linking adipose tissue dysfunction to metabolic and vascular diseases.
The Helmholtz Institute for Metabolic, Obesity, and Vascular Research (Helmholtz-Institut für Metabolismus-, Adipositas- und Gefäßforschung, HI-MAG) in Leipzig investigates molecular mechanisms linking adipose tissue dysfunction to metabolic and vascular diseases.
Take a look at our Metabolic Chambers:
Clinical Studies
Our clinical studies are part of our Clinicial Trial Unit and carried out in cooperation with the Leipzig Medical Center. For further information, please click here.
![["AdobeStock_LceYF3.png","AdobeStock_539562485.jpeg"]](https://images.admiralcloud.com/v5/deliverEmbed/c51f9442-15e8-408b-98a7-5f9d5c8f8b8f/image_webp/cropperjsfocus/3840/2010/0,0,3840,2010,0,1,1/1919.9999999999998,1004.9999999999999?poc=true "Grafik zum Thema Ernährung")
Director of the Helmholtz Institute for Metabolic, Obesity and Vascular Research and Head of Research Group Clinical Obesity Research
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HI-MAG Institute's Manager
Publications of HI-MAG
Jäger, E. ; Peeva, V. ; Gnad, T. ; Haange, S.B. ; Rolle-Kampczyk, U. ; Stäubert, C. ; Krumbholz, P. ; Heiker, J.T. ; Gebhardt, C. ; Krügel, U. ; Sen, P. ; Harazin, M. ; Stab, V. ; Münzker, J. ; Hamdani, N. ; Pfeifer, A. ; von Bergen, M. ; Till, A. ; Fenske, W.K.
Antibiotic-mediated modulation of the gut microbiome identifies taurine as a modulator of adipocyte function through TGR5 signaling.Nauck, M.A. ; Tuttle, K.R. ; Tschöp, M.H. ; Blüher, M.
Glucagon-like receptor agonists and next-generation incretin-based medications: Metabolic, cardiovascular, and renal benefits.Jalkanen, J. ; Zhong, J. ; Nono Nankam, P.A. ; Bhalla, N. ; Elmastas, M. ; Luo, J. ; Weinbrenner, S. ; Frendo-Cumbo, S. ; Pesti, B. ; Gourash, W. ; Courcoulas, A. ; Yang Loureiro, Z. ; Dietrich, A. ; Bäckdahl, J. ; Thorell, A. ; Buggert, M. ; Kalucka, J. ; Emont, M.P. ; Rosen, E.D. ; Blüher, M. ; Kovacs, P. ; Ståhl, P.L. ; Massier, L. ; Rydén, M. ; Mejhert, N.
Cytoarchitectural multi-depot profiling reveals immune-metabolic crosstalk in human colon-associated adipose tissue.Winther, B. ; Schmidt, A. ; Wilz, S. ; Scheinert, D. ; Fischer, A. ; Düsing, S. ; Steiner, S. ; Wittig, T.
Retrograde access via direct puncture of the occluded segment in complex femoropopliteal chronic total occlusions.Breitfeld, J. ; Horn, K. ; Velluva, A. ; Beyer, F. ; Pott, J. ; Baber, R. ; Stumvoll, M. ; Le Duc, D. ; Witte, V. ; Giontella, A. ; Melander, O. ; Kovacs, P. ; Scholz, M. ; Tönjes, A.
Genetic dissection of serum pro-neurotensin suggests potential causal impact on brain structure.Hagemann, T. ; Hoffmann, A. ; Rohde-Zimmermann, K. ; Broghammer, H. ; Massier, L. ; Kovacs, P. ; Stumvoll, M. ; Blüher, M. ; Heiker, J.T. ; Weiner, J.
Diet and temperature interactively impact brown adipose tissue gene regulation controlled by DNA methylation.Chakaroun, R.M. ; Pradhan, M. ; Björnson, E. ; Arvidsson, D. ; Fridolfsson, J. ; Gummesson, A. ; Schoeler, M. ; Mitteregger, M. ; Smith, G.J. ; Larsson, I. ; Börjesson, M. ; Blüher, M. ; Uhlén, M. ; Stumvoll, M. ; Bergström, G. ; Tremaroli, V. ; Bäckhed, F.
Multi-omic definition of metabolic obesity through adipose tissue-microbiome interactions.Gilani, A. ; Stein, B.D. ; Hoffmann, A. ; Pereira de Lima, R. ; Ha, E.E. ; Homan, E.A. ; Ma, L. ; Rubio-Navarro, A. ; Tha Ra Wun, T. ; Ayala Carrascal, G.J. ; Bhinder, B. ; Ghosh, A. ; Noé, F. ; Elemento, O. ; Wolfrum, C. ; Blüher, M. ; Lo, J.C.
Secretory kinase FAM20C triggers adipocyte dysfunction, inciting insulin resistance and inflammation in obesity.Sievenpiper, J.L. ; Ard, J. ; Blüher, M. ; Chen, W. ; Dixon, J.B. ; Fitch, A. ; Gigliotti, L. ; Khunti, K. ; Lecube, A. ; Lean, M.E.J. ; Mittendorfer, B. ; Pfeiffer, A.F.H. ; Ryan, D.H. ; Vilsbøll, T. ; Van Gaal, L.F.
Nutritional and lifestyle supportive care recommendations for management of obesity with GLP-1 - based therapies: An expert consensus statement using a modified Delphi approach.Xiao, L. ; De Jesus, D.F. ; Ju, C.W. ; Wei, J.B. ; Hu, J. ; DiStefano-Forti, A. ; Gonzales, V.S. ; Tsuji, T. ; Wei, S. ; Blüher, M. ; Tseng, Y.H. ; He, C. ; Kulkarni, R.N.
Divergent roles of m6A in orchestrating brown and white adipocyte transcriptomes and systemic metabolism.Contact
Leipzig University
University of Leipzig Medical Center
Leipzig Center of Metabolism (LeiCeM)
(Link will follow soon.)
European Association for the Study of Diabetes (EASD)
German Diabetes Association (Deutsche Diabetes Gesellschaft DDG)
Helmholtz Zentrum für Umweltforschung (UFZ)
Ben-Gurion University of the Negev
Karolinska Institutet
German Center for Child and Adolescent Health (DZKJ)
