Helmholtz Diabetes Center
Helmholtz Institute for Metabolic, Obesity, and Vascular Research
The Helmholtz Institute for Metabolic, Obesity, and Vascular Research (Helmholtz-Institut für Metabolismus-, Adipositas- und Gefäßforschung, HI-MAG) in Leipzig investigates molecular mechanisms linking adipose tissue dysfunction to metabolic and vascular diseases.
The Helmholtz Institute for Metabolic, Obesity, and Vascular Research (Helmholtz-Institut für Metabolismus-, Adipositas- und Gefäßforschung, HI-MAG) in Leipzig investigates molecular mechanisms linking adipose tissue dysfunction to metabolic and vascular diseases.
Take a look at our Metabolic Chambers:
Clinical Studies
Our clinical studies are part of our Clinicial Trial Unit and carried out in cooperation with the Leipzig Medical Center. For further information, please click here.
Publications of HI-MAG
Long, F. ; Ghosh, A. ; Xu, T. ; Ding, L. ; Wu, C. ; Khandelwal, R. ; Noé, F. ; Sun, W. ; Dong, H. ; Wang, T. ; Hoffmann, A. ; Gardeux, V. ; Deplancke, B. ; Abu-Nawwas, L. ; Stefanicka, P. ; Varga, L. ; Ruiz, J.R. ; Blüher, M. ; Balaz, M. ; Sharma, A.K. ; Wolfrum, C.
MEDAG functions as an A-kinase-anchoring protein in adipocytes.Bamberger, R. ; Lotter, L.D. ; Nieto, N. ; Poulain, T. ; Körner, A. ; Kiess, W. ; Fuchs, M. ; von Polier, G.
Voices of change: Associations between vocal markers and symptoms of ADHD - Findings from the LIFE child study.Wanner, C. ; Cosentino, F. ; Barnard-Kelly, K. ; Battelino, T. ; Blüher, M. ; Boll, H.N. ; Brosius, F.C. ; Busetto, L. ; Ceriello, A. ; Gavin, J.R. ; Giorgino, F. ; Green, J. ; Ji, L. ; Kellerer, M. ; Koob, S. ; Lalic, N. ; Marx, N. ; Nedungadi, P. ; Parkin, C.G. ; Rodbard, H.W. ; Rydén, L. ; Saboo, B. ; Sheu, W.H. ; Standl, E. ; Tacke, F. ; Topsever, P. ; Schnell, O.
From global guidelines for cardio-kidney-metabolic diseases management to national implementation: Perspectives from the guideline workshop taskforce.Zimmermann, P. ; Kaar, M. ; Bokeloh, T. ; Moll, L. ; Labinski, F. ; Eippert, F. ; Blüher, M. ; Stumvoll, M. ; Heinitz, S. ; Schlögl, H.
Changes in temperature perception in transgender persons undergoing gender-affirming hormone therapy.Prengemann, L. ; Stein, R. ; Gausche, R. ; Beger, C. ; Vogel, M. ; Wenzel, E. ; Stoltze, A. ; Kiess, W. ; Pfäffle, R. ; Körner, A.
Children born SGA receiving growth hormone have similarly impaired glucose-insulin metabolism as children with obesity.Klein, H. ; Pachter, D. ; Goldberg Toren, D.T. ; Kamer, O. ; Alufer, L. ; Ebstein Karamani, N. ; Chassidim, Y. ; Shelef, I. ; Rudich, A. ; Yoel, U. ; Ben-Arie, G. ; Zelicha, H. ; Yaskolka Meir, A. ; Tsaban, G. ; Bartal, C. ; Blüher, M. ; Stumvoll, M. ; Ceglarek, U. ; Isermann, B. ; Qi, L. ; Stampfer, M.J. ; Hu, F.B. ; Shai, I.
How effective is rejoining a long-term weight loss program? The 5- and 10-year MRI-assessed Follow Interventions Trial (FIT) project.Wittig, T. ; Schmidt, A. ; Zeller, T. ; Tepe, G. ; Thieme, M. ; Maiwald, L. ; Schröder, H. ; Euringer, W. ; Popescu, C. ; Brechtel, K. ; Brucks, S. ; Blessing, E. ; Schuster, J. ; Langhoff, R. ; Schellong, S. ; Weiss, N. ; Beschorner, U. ; Winther, B. ; Scheinert, D. ; Steiner, S.
Low-dose versus high-dose drug-coated balloons for femoropopliteal lesions: 5-year results from the prospective, randomised COMPARE trial.Papa, C. ; Rose, A. ; Martin, H.N.G. ; Useini, A. ; Geier, F. ; Liao, L. ; Rodriguez Aguilera, J.R. ; Valina-Allo, P. ; Hoffmann, A. ; Tvardovskiy, A. ; Zulfqar, F. ; Zimmerman, A. ; Schicht, G. ; Ott, F. ; Körner, C. ; Engelmann, B. ; Rolle-Kampczyk, U. ; von Bergen, M. ; Meier, M. ; Bartke, T. ; Seehofer, D. ; Klöting-Blüher, N. ; Matz-Soja, M. ; Damm, G. ; Boeckel, J.N. ; Buescher, J.M. ; Blüher, M. ; Laufs, U. ; Bondareva, O. ; Sträter, N. ; Künze, G. ; Heiker, J.T. ; Sheikh, B.N.
Bempedoic acid directly binds and activates PPARα.Jäger, E. ; Peeva, V. ; Gnad, T. ; Haange, S.B. ; Rolle-Kampczyk, U. ; Stäubert, C. ; Krumbholz, P. ; Heiker, J.T. ; Gebhardt, C. ; Krügel, U. ; Sen, P. ; Harazin, M. ; Stab, V. ; Münzker, J. ; Hamdani, N. ; Pfeifer, A. ; von Bergen, M. ; Till, A. ; Fenske, W.K.
Antibiotic-mediated modulation of the gut microbiome identifies taurine as a modulator of adipocyte function through TGR5 signaling.Nauck, M.A. ; Tuttle, K.R. ; Tschöp, M.H. ; Blüher, M.
Glucagon-like receptor agonists and next-generation incretin-based medications: Metabolic, cardiovascular, and renal benefits.