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Helmholtz Diabetes Center Helmholtz Institute for Metabolic, Obesity, and Vascular Research

The Helmholtz Institute for Metabolic, Obesity, and Vascular Research (Helmholtz-Institut für Metabolismus-, Adipositas- und Gefäßforschung, HI-MAG) in Leipzig investigates molecular mechanisms linking adipose tissue dysfunction to metabolic and vascular diseases.

The Helmholtz Institute for Metabolic, Obesity, and Vascular Research (Helmholtz-Institut für Metabolismus-, Adipositas- und Gefäßforschung, HI-MAG) in Leipzig investigates molecular mechanisms linking adipose tissue dysfunction to metabolic and vascular diseases.

Take a look at our Metabolic Chambers:

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Research Groups

Obesity overweight diabetes fitness abdomen adult background
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Blüher Lab

Clinical Obesity Research

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Körner Lab

Childhood Obesity and Metabolic Research

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Revaskularisation der Arteria femoralis superficialis
Helmholtz Munich | Sabine Steiner
Steiner Lab

Applied Vascular Research

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Adipocytes fats cells
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Modell eines Gehirns mit Nervenzelle
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Jais Lab

Diet-Induced Metabolic Alterations

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Moleküle im Zellkern
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Kristallstruktur von Vaspin
Helmholtz Munich | John Heiker
Heiker Lab

Molecular Obesity Research

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Clinical Studies

Klinische Studien

Our clinical studies are part of our Clinicial Trial Unit and carried out in cooperation with the Leipzig Medical Center. For further information, please click here.

 

Die Klinischen Studien am HI-MAG werden in enger Zusammenarbeit mit dem Universitätsklinikum Leipzig in der Studienambulanz unserer Clincial Trial Unit durchgeführt. Weiterführende Informationen dazu finden Sie hier.

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Kraft, Motivation
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CO-FU-Study / Childhood Obesity Follow-Up Study

Study on the Causes and Consequences of Obesity in Children, Adolescents and Yound Adults

More information on the study
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HHS-Study / Hormones and Health Study

Study on the Effects of the Hormones Estrogen and Testosterone on Eating Behavior, Metabolism, Sensory Function and the Cardiovascular System

More information on the study
Waage - Übergewicht 115kg
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DAYBREAK Trial und EMANATE Trial

Phase 2 and 3 Treatment Studies with Setmelanotide in Patients with Obesity and Rare Genetic Defects in the MC4 Receptor Signaling Pathway

More information on the study
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©Helmholtz Munich | Nadine Gibler
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Crack-it Study

Direct Comparison Between Lithotripsy-Based and Standard Lesion Preparation Using Balloon Angioplasty and Subsequent Supera Stent Implantation in Femoropopliteal Lesions with Severe Calcification

More information on the study

HI-MAG News

People @ HI-MAG

PI-/MA-Bilder Matthias Blüher_EH6A7638_Hintergrund freigestellt

Prof. Dr. Matthias Blüher

HI-MAG Director and Head of Clinical Obesity Research Group View profile
MA-Foto Konstanze Julich-Gruner_E6A8082_Hintergrund freigestellt

Dr. Konstanze Julich-Gruner

HI-MAG Institute's Manager
Mitarbeiterin-/PI-Foto Antje Körner

Prof. Dr. Antje Körner

Head of Childhood Obesity & Metabolic Research Group View profile
IMG_E0229_Zuschnitt_Sabine Steiner

Prof. Dr. Sabine Steiner

Head of Applied Vascular Research Group View profile
MA-Foto John Heiker_freigestellt

PD Dr. Dr. John Heiker

Group Leader "Molecular Obesity Research" View profile

Dr. Alexander Jais

Group Leader "Diet-Induced Metabolic Alterations" View profile
MA-Foto Lucas Massier 01.2025 - freigestellt

Dr. Lucas Massier

Group Leader "Adipose Tissue Microarchitecture and Metabolism" View profile
Mitarbeiter-/PI-Porträt Michael Stumvoll

Prof. Dr. Michael Stumvoll

Clinical Programme Director Clinical Trial Unit View profile
Maxi Albert

Maxi Albert

PhD Candidate, Massier Lab
Omar Alhaji_edit_freigestellt

Omar Alhaji

PhD Candidate, Körner Lab
MA-Foto Steffi Anding_EH6A8033_Hintergrund freigestellt

Steffi Anding

Project Assistant, Steiner Lab
MA-Foto Adel Ben-Kraiem_freigestellt

Dr. Adel Ben-Kraiem

PostDoc, Jais Lab
MA-Foto Susan Berthold - freigestellt

Susan Berthold

Technician, Blüher Lab
MA-Foto Olga Bondareva_neu 2023_freigestellt

Dr. Olga Bondareva

PostDoc (currently on maternity leave), Steiner Lab
MA-Foto Helen Broghammer

Helen Broghammer

PhD Candidate, Heiker Lab
Friederike Butter_IMG_2098_edit_neu

Friederike Butter

Student Assistant, Institute´s management
MA-Foto Janine Brunotte - freigestellt

Janine Brunotte

Project Assistant, Steiner Lab
MA-Foto Kushan Ranakombu_freigstellt

Dr. Kushan Kumara De Silva Ranakombu

Postdoc, Körner Lab
MA Foto Lorenz Donndorf EH6A2639 - freigestellt

Lorenz Donndorf

PhD Candidate, Sheikh Lab
MA-Foto Fabiana dos Santos Oliveira_Fabiana 3_Hintergrund freigestellt

Fabiana dos Santos Oliveira

PhD Candidate, Sheikh Lab
MA-Foto Lutz Feige_Hintergrund freigestellt

Lutz Feige

Technician, Blüher Lab
MA-Foto Sarah Victoria Frenzel - freigestellt

Sarah V. Frenzel

Coordinator Clinical Trial Unit
MA-Foto Claudia Gebhardt - freigestellt

Claudia Gebhardt

Technician, Heiker Lab
MA-Foto Florian Geier_EH6A8042_Hintergrund freigestellt

Florian Geier

Technician, Sheikh Lab
MA-Foto-Tobias-Hagemann_1_Tobias_komplett_Hintergrund freigestellt

Tobias Hagemann

Bioinformatician, Blüher Lab
MA-Foto Martha Hanschkow - freigestellt

Martha Hanschkow

PhD candidate, Körner Lab
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Marlene Hausner

Technician, Steiner Lab
MA-Foto Sascha Heinitz - freigestellt

Dr. Sascha Heinitz

Clinician Scientist
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Dr. Anne Hoffmann

Team Leader Bioinformatics, Blüher Lab
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Daniela Kern

Technician, Blüher Lab
MA-Foto Matthias Kern 2_ganz_Hintergrund freigestellt

Dr. Matthias Kern

Lab Coordinator

PD Dr. Nora Klöting

Group Leader
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Sontje Krupka

PhD Candidate, Blüher Lab
MA-Foto Kathrin Landgraf - freigestellt

Dr. Kathrin Landgraf

Guest Researcher, Körner Lab
MA-Foto Longsheng Liao_EH6A8131_Hintergrund freigestellt

Longsheng Liao

PhD Candidate, Sheikh Lab
MA-Foto Nishtha Malhotra EH6A2665_freigestellt

Nishtha Malhotra

PhD Candidate, Sheikh Lab
Christin Mannewitz

Christin Mannewitz

Team Assistant, Körner Lab

Hugo Martin

PhD Candidate, Sheikh Lab
MA-Foto Klara Meyer EH6A7405_freigestellt

Dr. Klara Meyer

Clinician Scientist (currently on parental leave), Körner Lab
MA-Foto Anja Moll - freigestellt

Anja Moll

Technician, Jais Lab

Dr. Katja Mühlberg

Guest Researcher, Steiner Lab

Olivia Paetow

Technician, Heiker Lab
MA-Foto Christina Papa - freigestellt

Christina Papa

PhD Candidate, Sheikh Lab
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Dr. Katja Piotrowski

Science Manager, Körner Lab
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Alessio Pollastri

PhD Candidate, Blüher Lab
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Dr. Mariana Ponce de Léon Rodríguez

Postdoc, Körner Lab
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Stephanie Puente Ruiz

PhD Candidate, Jais Lab
MA-Foto Susanne Renno_IMG_0179_Hintergrund freigestellt

Susanne Renno

Assistant to the Director
MA-Foto Alina Rose_Alina_ganz 2_Hintergrund freigstellt

Alina Rose

Scientist, Institute´s Management
MA_Foto Kristin Röhrborng_EH6A7140-2_Hintergrund freigestellt

Kristin Röhrborn

PhD Candidate, Blüher Lab
Claudia Ruffert

Claudia Ruffert

Technician, Blüher Lab
Asma Saidi

Asma Saidi

PhD Candidate, Jais Lab

Natalia Schischkarjow

Study Assistant Clinical Trial Unit
MA-Foto Haiko Schlögl -  freigestellt

PD Dr. med. Haiko Schlögl

Clinician Scientist
MA-Foto Julia Schuller EH6A2724_freigestellt

Dr. Julia Schuller

PostDoc, Jais Lab
MA-Foto Robert Stein - freigestellt

Dr. Robert Stein

Clinician Scientist, Körner Lab
MA-Foto Christian Strehlau EH6A4702 - freigestellt

Christian Strehlau

PhD Candidate, Heiker Lab
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Dr. Juliane Weiner

Clinician Scientist
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Dr. Eric Wenzel

Clinician Scientist, Körner Lab

Birte Winther

Clinician Scientist, Steiner Lab
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Dr. Tim Wittig

Clinician Scientist, Steiner Lab

He Yao

PhD Candidate, Sheikh Lab
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Sandra Zentile

Public Relations Clerk / Team Assistant
MA-Foto Faiqa Zulfqar_EH6A7420-Edit_Hintergrund freigestellt

Faiqa Zulfqar

PhD Candidate, Sheikh Lab

Publications of HI-MAG

Read more

2025 Scientific Article in Nature Genetics

Lazarescu, O. ; Ziv-Agam, M. ; Haim, Y. ; Hekselman, I. ; Jubran, J. ; Shneyour, A. ; Muallem, H. ; Zemer, A. ; Rosengarten-Levin, M. ; Kitsberg, D. ; Levin, L. ; Liberty, I.F. ; Yoel, U. ; Dukhno, O. ; Adam, M. ; Braune, J. ; Müller, C. ; Raulien, N. ; Gericke, M. ; Körner, A. ; Murphy, R. ; Blüher, M. ; Habib, N. ; Rudich, A. ; Yeger-Lotem, E.

Human subcutaneous and visceral adipocyte atlases uncover classical and nonclassical adipocytes and depot-specific patterns.

2025 Review in Lancet Diabetes and Endocrinology

Rubino, F. ; Cummings, D.E. ; Eckel, R.H. ; Cohen, R.V. ; Wilding, J.P.H. ; Brown, W.A. ; Stanford, F.C. ; Batterham, R.L. ; Farooqi, I.S. ; Farpour-Lambert, N.J. ; le Roux, C.W. ; Sattar, N. ; Baur, L.A. ; Morrison, K.M. ; Misra, A. ; Kadowaki, T. ; Tham, K.W. ; Sumithran, P. ; Garvey, W.T. ; Kirwan, J.P. ; Fernández-Real, J.M. ; Corkey, B.E. ; Toplak, H. ; Kokkinos, A. ; Kushner, R.F. ; Branca, F. ; Valabhji, J. ; Blüher, M. ; Bornstein, S.R. ; Grill, H.J. ; Ravussin, E. ; Gregg, E.W. ; Al Busaidi, N.B. ; Alfaris, N.F. ; Al Ozairi, E. ; Carlsson, L.M.S. ; Clément, K. ; Després, J.P. ; Dixon, J.B. ; Galea, G. ; Kaplan, L.M. ; Laferrère, B. ; Laville, M. ; Lim, S. ; Luna Fuentes, J.R. ; Mooney, V.M. ; Nadglowski, J. ; Urudinachi, A. ; Olszanecka-Glinianowicz, M. ; Pan, A. ; Pattou, F. ; Schauer, P.R. ; Tschöp, M.H. ; van der Merwe, M.T. ; Vettor, R. ; Mingrone, G.

Definition and diagnostic criteria of clinical obesity.

Contact HI-MAG Office

MA-Foto Sandra Zentile_Sandra 1_ganz_Hintergrund freigestellt

Sandra Zentile

Public Relations Clerk / Team Assistant

Leipzig

Contact Prof. Blüher's Office

MA-Foto Susanne Renno_IMG_0179_Hintergrund freigestellt

Susanne Renno

Assistant to the Director

Leipzig

Institute's Management

MA-Foto Konstanze Julich-Gruner_E6A8082_Hintergrund freigestellt

Dr. Konstanze Julich-Gruner

HI-MAG Institute's Manager

Leipzig