Diabetes

Our research at the Helmholtz Diabetes Center (HDC) aims to understand the molecular bases underlying all forms of diabetes, its heterogeneity, and risk factors, including obesity, as well as its complications and comorbidities. We combine world-leading basic research with clinical intervention and cohort studies to develop tomorrow’s diabetes precision medicine.

Our research at the Helmholtz Diabetes Center (HDC) aims to understand the molecular bases underlying all forms of diabetes, its heterogeneity and risk factors, including obesity, as well as its complications and comorbidities. We combine world-leading basic research with clinical intervention and cohort studies to develop tomorrow’s diabetes precision medicine.

Molecular model of insulin molecule, 3D illustration

We identify risk factors for diabetes in children and adults and its complications. Our world-class basic research enables us to define new biomarker for its development and progression and therapeutic targets.

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We are leading in early detection and prevention of type 1 and type 2 diabetes as well as development of innovative personalized therapies to combat diabetes and obesity.

3d rendering of Human cell or Embryonic stem cell microscope background.

We develop new venues for cell-based therapies, to reestablish a health metabolic function. We jointly work to identify the molecular basis of diabetes complications and means for their remission.

Diabetes in Children

Early detection tests for a world without type 1 diabetes

At Helmholtz Munich, scientists are working to ensure that no child will have to suffer from the autoimmune disease type 1 diabetes in the future.

Networks

Our partnerships for a world without diabetes

Researchers at Helmholtz Munich are working toward a world without diabetes. They are not doing so alone, but with a network of organizations, hospitals, and pharmaceutical companies. Their goal is to use experts’ knowledge to create something new: innovative prevention and treatment of diabetes.

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Metabolism and Longevity

Longevity Treatments Do Not Slow Aging

Three approaches with a reputation for slowing aging processes have proven largely ineffective. For their study, researchers developed a new method to measure aging, which accounts for the complexity of aging in organisms.

Martin Hrabe de Angelis _ Portrait NEU_freigestellt

Prof. Dr. Dr. h.c. Martin Hrabě De Angelis

Member and Spokesperson of the Executive Board (acting), Research Director Helmholtz Munich, Full Professor and Chair of Experimental Genetics Technical University Munich, Director of the Institute of Experimental Genetics Helmholtz Munich

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Prof. Dr. Stephan Herzig

Research Director Helmholtz Munich, Head of Diabetes Department and Head of Research Unit "Diabetes and Complications"

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Prof. Dr. Heiko Lickert

Institute Director

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Univ.-Prof. Dr. med. Anette-Gabriele Ziegler

Institute Director, Chair of Diabetes and Gestational Diabetes, Klinikum rechts der Isar and Technical University of Munich, Director of the Global Platform for the Prevention of Autoimmune Diabetes (GPPAD)

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Prof. Dr. Timo Müller

Institute Director, Head of Research Unit Molecular Pharmacology

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Prof. Dr. Michele Solimena

Institute Director

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Prof. Dr. Tor Henrik Semb

Director

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PI-/MA-Bilder Matthias Blüher_EH6A7638_Hintergrund freigestellt

Prof. Dr. Matthias Blüher

Director of the Helmholtz Institute for Metabolic, Obesity and Vascular Research and Head of Research Group Clinical Obesity Research

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Henriette Uhlenhaut Porträt freigestellt

Prof. Dr. Nina Henriette Uhlenhaut

Institute Director

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Paul Pfluger Portrait Hochformat_freigestellt

Prof. Dr. Paul Pfluger

Head of Research Unit

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Profilbild Andreas BIrkenfeld_freigestellt

Prof. Dr. Andreas Birkenfeld

Director

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Prof. Dr. Matthias Hebrok

Director, IDOT

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Dr. Siegfried Ussar

Director of Research Unit Adipocytes and Metabolism

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Prof. Carolin Daniel

IMI Director

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Banner 13. Diabetes Konferenz für Homepage der Konferenz

The 13th Helmholtz Diabetes Conference will be hosted by Stephan Herzig and co-organized by Antje Körner and Raffaele Teperino. This year, a special focus will be put on "Diabetes Across The Lifespan".

To the conference website

Thanks to basic research, groundbreaking innovations against obesity as well as in the field of diabetes prevention and therapy are emerging at Helmholtz Munich.

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The American Diabetes Association (ADA) has announced the recipients of this year's National Scientific and Health Care Achievement Awards. Among this year’s awardees is Prof. Timo Müller, Director of the Institute for Diabetes and Obesity (IDO) at…

Nurse and patient in hospital bed with medical monitors

How can we bring new scientific insights to patients more quickly? At Helmholtz Munich, we work hand in hand with leading clinics across Germany to translate research findings directly and purposefully into new therapeutic approaches — and,…

Helmholtz Munich has been awarded a prestigious grant of up to 900 000 US Dollar from Breakthrough T1D, the leading global type 1 diabetes (T1D) research and advocacy organization. The funding will support the research into early-stage T1D in adults,…

The journal Metabolism honors Dr. Anja Schork, who works at the Institute for Diabetes Research and Metabolic Diseases at Helmholtz Munich at the University of Tübingen and at the German Center for Diabetes Research (DZD), with the Junior Faculty…

Prof. Sandra Hummel, lead scientist of the research area “Lifestyle, Obesity, and Epigenetic Programming in Type 1 and Gestational Diabetes” at the Institute of Diabetes Research at Helmholtz Munich, has been awarded the Dr. Heinz Bürger-Büsing…

Cardiovascular diseases are the leading cause of death worldwide, and lowering blood lipids is a central strategy to reduce risk. Bempedoic acid, a recently approved cholesterol-lowering drug, has now been shown by researchers at Helmholtz Munich to…

Loft A, Schmidt SF, Caratti G, Stifel U, Havelund J, Sekar R, Kwon Y, Sulaj A, Chow KK, Alfaro AJ, Schwarzmayr T, Rittig N, Svart M, Tsokanos FF, Maida A, Blutke A, Feuchtinger A, Møller N, Blüher M, Nawroth P, Szendrödi J, Færgeman NJ, Zeigerer A, Tuckermann J, Herzig S.

A macrophage-hepatocyte glucocorticoid receptor axis coordinates fasting ketogenesis.

Karlina R, Flexeder C, Stephanie M, Bhattacharyya M, Schneider E, Altun I, Gschwendtner S, Neumann AU, Nano J, Schloter M, Peters A, Schulz H, Schmidt-Weber CB, Standl M, Traidl-Hoffmann C, Alessandrini F, Ussar S.

Differential effects of lung inflammation on insulin resistance in humans and mice.

Karl FM, Winkler C, Ziegler A-G, Laxy M, Achenbach P

Costs of Public Health Screening of Children for Presymptomatic Type 1 Diabetes in Bavaria, Germany.

Xu CS, Pang S, Shtengel G, Müller A, Ritter AT, Hoffman HK, Takemura SY, Lu Z, Pasolli HA, Iyer N, Chung J, Bennett D, Weigel AV, Freeman M, van Engelenburg SB, Walther TC, Farese RV Jr, Lippincott-Schwartz J, Mellman I, Solimena M, Hess HF.

An open-access volume electron microscopy atlas of whole cells and tissues.