Diabetes

Our research at the Helmholtz Diabetes Center (HDC) aims to understand the molecular bases underlying all forms of diabetes, its heterogeneity, and risk factors, including obesity, as well as its complications and comorbidities. We combine world-leading basic research with clinical intervention and cohort studies to develop tomorrow’s diabetes precision medicine.

Our research at the Helmholtz Diabetes Center (HDC) aims to understand the molecular bases underlying all forms of diabetes, its heterogeneity and risk factors, including obesity, as well as its complications and comorbidities. We combine world-leading basic research with clinical intervention and cohort studies to develop tomorrow’s diabetes precision medicine.

Molecular model of insulin molecule, 3D illustration

We identify risk factors for diabetes in children and adults and its complications. Our world-class basic research enables us to define new biomarker for its development and progression and therapeutic targets.

Institut für Diabetesforschung Studienzentrum

We are leading in early detection and prevention of type 1 and type 2 diabetes as well as development of innovative personalized therapies to combat diabetes and obesity.

3d rendering of Human cell or Embryonic stem cell microscope background.

We develop new venues for cell-based therapies, to reestablish a health metabolic function. We jointly work to identify the molecular basis of diabetes complications and means for their remission.

Diabetes in Children

Early detection tests for a world without type 1 diabetes

At Helmholtz Munich, scientists are working to ensure that no child will have to suffer from the autoimmune disease type 1 diabetes in the future.

Networks

Our partnerships for a world without diabetes

Researchers at Helmholtz Munich are working toward a world without diabetes. They are not doing so alone, but with a network of organizations, hospitals, and pharmaceutical companies. Their goal is to use experts’ knowledge to create something new: innovative prevention and treatment of diabetes.

Panoramic teamwork business join hand together concept, Business team standing hands together, Volunteer charity work. People joining for cooperation success business.

Metabolism and Longevity

Longevity Treatments Do Not Slow Aging

Three approaches with a reputation for slowing aging processes have proven largely ineffective. For their study, researchers developed a new method to measure aging, which accounts for the complexity of aging in organisms.

freigestelltes Porträtbild für Kontakte auf der Website

Prof. Dr. Dr. h.c. Martin Hrabě De Angelis

Member and Spokesperson of the Executive Board (acting), Research Director Helmholtz Munich, Full Professor and Chair of Experimental Genetics Technical University Munich, Director of the Institute of Experimental Genetics Helmholtz Munich

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Prof. Dr. Stephan Herzig

Research Director Helmholtz Munich, Head of Diabetes Department and Head of Research Unit "Diabetes and Complications"

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Prof. Dr. Heiko Lickert

Director, Institute of Diabetes and Regeneration Research, IDR

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Univ.-Prof. Dr. med. Anette-Gabriele Ziegler

Institute Director, Chair of Diabetes and Gestational Diabetes, Klinikum rechts der Isar and Technical University of Munich, Director of the Global Platform for the Prevention of Autoimmune Diabetes (GPPAD)

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Prof. Dr. Timo Müller

Institute Director, Head of Research Unit Molecular Pharmacology, IDO

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Prof. Dr. Michele Solimena

Director of the Institute for Pancreatic Islet Research, IPI

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Prof. Dr. Tor Henrik Semb

Director, Institute of Translational Stem Cell Research, ITS

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PI-/MA-Bilder Matthias Blüher_EH6A7638_Hintergrund freigestellt

Prof. Dr. Matthias Blüher

Director of the Helmholtz Institute for Metabolic, Obesity and Vascular Research and Head of Research Group Clinical Obesity Research, HI-MAG

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Henriette Uhlenhaut Porträt freigestellt

Prof. Dr. Nina Henriette Uhlenhaut

Director of the Institute for Diabetes and Endocriology, IDE

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Prof. Dr. Paul Pfluger

Head of Research Unit NeuroBiology of Diabetes, NBD

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Prof. Dr. Andreas Birkenfeld

Director of the Institute of Diabetes Research and Metabolic Diseases (IDM) Helmholtz Munich at the University Hospital Tübingen

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Prof. Dr. Matthias Hebrok

Director, Institute for Diabetes and Organoid Technology, IDOT

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Dr. Siegfried Ussar

Director of Research Unit Adipocytes and Metabolism, ADM

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Prof. Carolin Daniel

Director of the Institute for Metabolism and Immunology, IMI

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Banner 13. Diabetes Konferenz für Homepage der Konferenz

The 13th Helmholtz Diabetes Conference will be hosted by Stephan Herzig and co-organized by Antje Körner and Raffaele Teperino. This year, a special focus will be put on "Diabetes Across The Lifespan".

To the conference website

Thanks to basic research, groundbreaking innovations against obesity as well as in the field of diabetes prevention and therapy are emerging at Helmholtz Munich.

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A daily routine for children with type 1 diabetes: monitoring blood glucose.

Research fully realizes its value where it reaches people – when findings translate into new treatment options from which those affected can benefit. How this can be achieved in practice for type 1 diabetes is demonstrated by the Institute of…

Dr. Robert Frömel and Dr. Hossam Montaser have been awarded Marie Skłodowska Curie Postdoctoral Fellowships. Over a period of two years, the EU funded fellowships will support their independent research projects on gene regulation in brain…

Cover of the Pixi book from Carlsen, which describes type 1 diabetes.

The new Pixi Wissen book, “Finn and the Sleepover – Type 1 Diabetes at School”, demonstrates how research can be translated into practical resources for everyday life. Together with partners, Helmholtz Munich has developed a scientifically grounded,…

Prof. Heiko Lickert has been awarded an ERC Proof of Concept (PoC) Grant from the European Research Council (ERC). The funding is intended to advance a novel regenerative therapeutic approach for type 2 diabetes from basic research into clinical…

A major international distinction for Leipzig-based obesity research: Prof. Antje Körner has been awarded the Willendorf Award by the World Obesity Federation.

FGF21 is primarily known as a metabolic hormone. A new study by researchers at Helmholtz Munich and the Ludwig Maximilians University has now described a previously unknown mechanism through which FGF21 supports cells under protein folding stress:…

Loft A, Schmidt SF, Caratti G, Stifel U, Havelund J, Sekar R, Kwon Y, Sulaj A, Chow KK, Alfaro AJ, Schwarzmayr T, Rittig N, Svart M, Tsokanos FF, Maida A, Blutke A, Feuchtinger A, Møller N, Blüher M, Nawroth P, Szendrödi J, Færgeman NJ, Zeigerer A, Tuckermann J, Herzig S.

A macrophage-hepatocyte glucocorticoid receptor axis coordinates fasting ketogenesis.

Karlina R, Flexeder C, Stephanie M, Bhattacharyya M, Schneider E, Altun I, Gschwendtner S, Neumann AU, Nano J, Schloter M, Peters A, Schulz H, Schmidt-Weber CB, Standl M, Traidl-Hoffmann C, Alessandrini F, Ussar S.

Differential effects of lung inflammation on insulin resistance in humans and mice.

Karl FM, Winkler C, Ziegler A-G, Laxy M, Achenbach P

Costs of Public Health Screening of Children for Presymptomatic Type 1 Diabetes in Bavaria, Germany.

Xu CS, Pang S, Shtengel G, Müller A, Ritter AT, Hoffman HK, Takemura SY, Lu Z, Pasolli HA, Iyer N, Chung J, Bennett D, Weigel AV, Freeman M, van Engelenburg SB, Walther TC, Farese RV Jr, Lippincott-Schwartz J, Mellman I, Solimena M, Hess HF.

An open-access volume electron microscopy atlas of whole cells and tissues.