All HDC Publications
2025 Position paper in Diabetologie, Die Diabetologie 21, 455-466 (2025)
Gestationsdiabetes mellitus (GDM), Diagnostik, Therapie und NachsorgeKurzfassung der S3-Leitlinie (AWMF-Registernummer: 057-008).
2025 Other: News Item in Nature Reviews - Endocrinology Nat. Rev. Endocrinol., DOI: 10.1038/s41574-025-01139-3 (2025)
Tirzepatide differentially affects body weight in mice and humans.
2025 Editorial in Journal of Steroid Biochemistry and Molecular Biology, The J. Steroid Biochem. Mol. Biol.:106808 (2025)
Frontiers in Steroid Research: Steroid Congress 2023.
2025 Scientific Article in European Journal of Preventive Cardiology Eur. J. Prev. Cardiol., DOI: 10.1093/eurjpc/zwaf308 (2025)
Individual response to lifestyle interventions: A pooled analysis of three long-term weight loss trials.
2025 Position paper in Diabetologie, Die Diabetologie 21, 488–502 (2025)
Therapie des Typ-2-Diabetes.
2025 Position paper in Diabetologie, Die Diabetologie 21, 467–472 (2025)
Lipidtherapie bei Patienten mitDiabetes mellitus.Eine gemeinsame Stellungnahme der KommissionFettstoffwechsel sowie der AG Diabetes und Herz derDeutschen Diabetes Gesellschaft (DDG), der SektionDiabetes, Adipositas und Stoffwechsel der DeutschenGesellschaft für Endokrinologie (DGE), der AG Herz undDiabetes der Deutschen Gesellschaft für Kardiologie (DGK)und der gemeinsamen AG Herz – Hormone – Diabetes derDGK, DGE und DDG.
2025 Scientific Article in Journal of Biological Chemistry, The J. Biol. Chem.:110296 (2025)
Secreted EMC10 inhibits muscle GLUT4 activity and glucose uptake in mice.
2025 Scientific Article in Environment International Environ. Int. 201:109566 (2025)
Associations of road traffic noise with adipose tissue depots and hepatic fat content - Results from the German National Cohort (NAKO).
2025 Review in Cardiovascular Diabetology Cardiovasc. Diabetol. 24:234 (2025)
The impact of dietary interventions on cardiometabolic health.
2025 Scientific Article in Cell Reports Cell Rep. 44:115765 (2025)
Adenosine signaling in glia modulates metabolic state-dependent behavior in Drosophila.
2025 Scientific Article in Diabetes Aktuell Diabetes akt. 23, 109-116 (2025)
Erkenntnisse aus der Fettgewebsforschung.
2025 Letter to the Editor in Liver International Liver Int. 45:e70160 (2025)
Response to Xu and Gao: Robustness of butyrylcholinesterase associations with liver fat and insulin sensitivity.
In: Cell Signaling Pathways and Their Therapeutic Implication in Cancers. 2025. 357-394
Role of signaling pathways regulating cell cycle progression in cancer.
2025 Scientific Article in Cell Cell, DOI: 10.1016/j.cell.2025.04.037 (2025)
The human proteome with direct physical access to DNA.
2025 Scientific Article in iMetaOmics iMetaOmics 2:e59 (2025)
Multi‐omics reveals different signatures of obesity‐prone and obesity‐resistant mice.
2025 Position paper in Diabetologie, Die Diabetologie, DOI: 10.1007/s11428-025-01320-2 (2025)
Diabetes mellitus und Herz.
2025 Review in Diabetes Care Diabetes Care 48, 1042-1052 (2025)
Sodium-glucose cotransporter 2 inhibitor use and risk of liver-related events in patients with type 2 diabetes: A meta-analysis of observational cohort studies.
2025 Review in Trends in Endocrinology and Metabolism Trends Endocrinol. Metab., DOI: 10.1016/j.tem.2025.04.010 (2025)
Expanding the understanding of insulin resistance in brain and periphery.
2025 Scientific Article in ACS Chemical Biology ACS Chem. Biol., DOI: 10.1021/acschembio.5c00108 (2025)
Serendipitous and systematic chemoproteomic discovery of MBLAC2, HINT1, and NME1-4 inhibitors from histone deacetylase-targeting pharmacophores.
2025 Scientific Article in International Journal of Molecular Sciences Int. J. Mol. Sci. 26, 4849 - 4849 (2025)
Baricitinib and lonafarnib synergistically target Progerin and inflammation, improving lifespan and health in progeria mice.
2025 Scientific Article in European Journal of Human Genetics Eur. J. Hum. Genet., DOI: 10.1038/s41431-025-01863-4 (2025)
Recessive variants in WSB2 encoding a substrate receptor of E3 ubiquitin ligase underlie a neurodevelopmental syndrome.
2025 Review in Nature metabolism Nat. Metab. 7, 875-894 (2025)
Towards a consensus atlas of human and mouse adipose tissue at single-cell resolution.
2025 Scientific Article in Journal of Clinical Medicine J. Clin. Med. 14:3188 (2025)
Evaluation of spinal cor blood supply with hyperspectral imaging of the paraspinous musculature during staged endovascular repair of thoracoabdominal aortic aneurysm: A sub-study of the prospective multicenter PAPA-ARTiS trial.
2025 Nature metabolism Nat. Metab., DOI: 10.1038/s42255-025-01308-8 (2025)
Publisher Correction: GIPR agonism and antagonism decrease body weight and food intake via different mechanisms in male mice.
2025 Editorial in Diabetologie, Die Diabetologie, DOI: 10.1007/s11428-025-01316-y (2025)
Semaglutid in der Behandlung von Menschen mit Adipositas,Herzinsuffizienz mit erhaltener Ejektionsfraktion und Diabetes mellitus Typ 2.
2025 Scientific Article in Molecular Metabolism Mol. Metab. 97:102161 (2025)
Abundance of a metabolically active subpopulation in dedifferentiated adipocytes inversely correlates with body mass index.
2025 Review in Cardiovascular Diabetology Cardiovasc. Diabetol. 24:187 (2025)
CVOT summit report 2024: New cardiovascular, kidney, and metabolic outcomes.
2025 Scientific Article in Cell Reports Cell Rep. 44:115522 (2025)
Reduced notch signaling in hypothalamic endothelial cells mediates obesity-induced alterations in glucose uptake and insulin signaling.
2025 Scientific Article in Molecular Metabolism Mol. Metab. 97:102163 (2025)
Pervasive glycative stress links metabolic imbalance and muscle atrophy in early-onset Parkinson's disease.
2025 Position paper in Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet., DOI: 10.1055/a-2500-0411 (2025)
Gestational diabetes mellitus (GDM), diagnostics, therapy and follow-up care.
2025 Editorial in Lancet Diabetes and Endocrinology Lancet Diabet. Endocrinol. 13, 455-457 (2025)
Does tirzepatide treatment improve skeletal muscle composition?
2025 Scientific Article in Early Human Development Early Hum. Dev. 206:106272 (2025)
Fetal heart rate variability in relation to maternal physical activity and metabolic health.
2025 Scientific Article in Journal of Cellular Physiology J. Cell. Physiol. 240:e70042 (2025)
Mg2+ supplementation mitigates metabolic deficits associated with TRPM7 disruption.
2025 Scientific Article in Nature metabolism Nat. Metab., DOI: 10.1038/s42255-025-01294-x (2025)
GIPR agonism and antagonism decrease body weight and food intake via different mechanisms in male mice.
2025 Review in Topics in Current Chemistry Top. Curr. Chem. 383:21 (2025)
Circular RNA, a molecule with potential chemistry and applications in RNA-based cancer therapeutics: An insight into recent advances.
2025 Scientific Article in Endocrinology Endocrinology 166:bqaf078 (2025)
Functional analysis of HSD17B3-deficient male mice reveals roles for HSD17B7 and HSD17B12 in testosterone biosynthesis.
2025 Scientific Article in Investigative Ophthalmology & Visual Science, IOVS Invest. Ophthalmol. Vis. Sci. 66:7 (2025)
Systematic ocular phenotyping of knockout mouse lines identifies genes associated with age-related corneal dystrophies.
2025 Scientific Article in Diabetes Therapy Diabetes Ther., DOI: 10.1007/s13300-025-01728-5 (2025)
Efficacy and safety of tirzepatide compared with GLP-1 RAs in patients with type 2 diabetes treated with basal insulin: A network meta-analysis.
2025 Scientific Article in Journal of Diabetes J. Diabetes 17:e70083 (2025)
Association of lifestyle-induced weight loss with gene expression in subcutaneous adipose tissue in metabolic syndrome.
2025 Scientific Article in Neuroscience Research Neurosci. Res., DOI: 10.1016/j.neures.2025.04.002 (2025)
Inflammation and autophagy in peripheral nerves of rodent models with metabolic syndrome and type 2 diabetes mellitus.
2025 Review in Innere Medizin Innere Med. 66, 475–484 (2025)
Medikamentöse Adipositastherapie in Deutschland.
2025 Letter to the Editor in Metabolism: clinical and experimental Metabolism:156269 (2025)
Reply to: Reconsidering KLK7's role in adipose inflammation: Letter to the editor.
2025 Review in European Journal of Preventive Cardiology Eur. J. Prev. Cardiol. 32, 184-220 (2025)
Obesity and cardiovascular disease: An ESC clinical consensus statement.
2025 Nature metabolism Nat. Metab. 7:855 (2025)
Publisher Correction: Cold-induced expression of a truncated adenylyl cyclase 3 acts as rheostat to brown fat function.
2025 Scientific Article in Journal of Cachexia, Sarcopenia and Muscle J. Cachexia Sarcopenia Muscle 16:e13781 (2025)
Housing temperature impacts the systemic and tissue-specific molecular responses to cancer in mice.
2025 Letter to the Editor in Diabetologia Diabetologia 68, 1352–1354 (2025)
The genetic architecture of type 1 diabetes over time: How well can we rely on past data to predict the future?
2025 Scientific Article in Diabetes Care Diabetes Care, DOI: 10.2337/dc24-2886 (2025)
Unfolding the mystery of autoimmunity: The environmental determinants of diabetes in the young (TEDDY) study.
2025 Scientific Article in Nature Communications Nat. Commun. 16:3750 (2025)
Genetics of circulating proteins in newborn babies at high risk of type 1 diabetes.
2025 Letter to the Editor in Nature medicine Nat. Med., DOI: 10.1038/s41591-025-03590-1 (2025)
Helmholtz Health task force to strengthen prevention research and its translation globally.
2025 Scientific Article in Diabetes Care Diabetes Care 48, 996-1006 (2025)
Subphenotype-dependent benefits of bariatric surgery for individuals at risk for type 2 diabetes.
2025 Scientific Article in Pflügers Archiv Pflugers Arch., DOI: 10.1007/s00424-025-03082-8 (2025)
Impact of aldosterone deficiency on the development of diuretic resistance in mice.
2025 Scientific Article in Brain stimulation Brain Stimul. 18, 863-874 (2025)
Repeated net-tDCS of the hypothalamus appetite-control network enhances inhibitory control and decreases sweet food intake in persons with overweight or obesity.
2025 Scientific Article in Liver International Liver Int. 45:e70046 (2025)
Elevated cholinesterase activity and the metabolic syndrome-dissecting fatty liver, insulin resistance and dysglycaemia.
2025 Scientific Article in Molecular Metabolism Mol. Metab. 96:102136 (2025)
Estrogenic activity of E2-conjugated GLP-1 is mediated by intracellular endolysosomal acidification and estrone metabolism.
2025 Review in Innere Medizin Innere Med., DOI: 10.1007/s00108-025-01893-6 (2025)
Inkretine als Grundlage der Adipositastherapie.
2025 Scientific Article in Science Advances Sci. Adv. 11:eadt7366 (2025)
A direct effect of the hematocrit on blood glucose: Evidence from hypoxia- and erythropoietin-treated mice.
2025 Editorial in Nature Reviews - Endocrinology Nat. Rev. Endocrinol., DOI: 10.1038/s41574-025-01116-w (2025)
mTORC1 is the central regulator in pancreatic β-cells.
2025 Scientific Article in International Journal of Obesity Int. J. Obes., DOI: 10.1038/s41366-025-01744-2 (2025)
Serum secreted EMC10 (scEMC10) levels are inversely associated with metabolically active brown adipose tissue in humans.
2025 Scientific Article in Scientific Reports Sci. Rep. 15:9354 (2025)
Stand-alone MRI tool for semiautomatic volumetry of abdominal adipose compartments in patients with obesity.
2025 Scientific Article in EBioMedicine EBioMedicine 114:105653 (2025)
Chromatin landscape in paired human visceral and subcutaneous adipose tissue and its impact on clinical variables in obesity.
2025 Scientific Article in Molecular Metabolism Mol. Metab. 95:102130 (2025)
Physical training reduces cell senescence and associated insulin resistance in skeletal muscle.
2025 Scientific Article in Metabolism: clinical and experimental Metabolism 168:156239 (2025)
The serine protease KLK7 promotes immune cell infiltration in visceral adipose tissue in obesity.
2025 Scientific Article in Frontiers in Endocrinology Front. Endocrin. 16:1567573 (2025)
Sex differences in diet-induced MASLD - are female mice naturally protected?
2025 Review in Diabetologia Diabetologia, DOI: 10.1007/s00125-025-06408-4 (2025)
The efficacy of islet autoantibody screening with or without genetic pre-screening strategies for the identification of presymptomatic type 1 diabetes.
2025 Scientific Article in BMC Pediatrics BMC Pediatr. 25:236 (2025)
Did smoking behavior change in adolescents and young adults with and without diabetes during the COVID-19 pandemic? A cohort study from the DPV registry.
2025 Scientific Article in Diabetes, Obesity and Metabolism Diabetes Obes. Metab., DOI: 10.1111/dom.16354 (2025)
Type 1 diabetes risk factors, risk prediction and presymptomatic detection: Evidence and guidance for screening.
2025 Review in Gastroenterology Gastroenterology, DOI: 10.1053/j.gastro.2025.01.241 (2025)
Early dietary fiber intake reduces celiac disease risk in genetically prone children: Insights from the TEDDY study.
2025 Scientific Article in Genes and Immunity Genes Immun., DOI: 10.1038/s41435-025-00324-8 (2025)
Age-dependent gene expression trajectories during early childhood in children at increased risk for type 1 diabetes.
2025 Scientific Article in Nature Communications Nat. Commun. 16:2744 (2025)
Regulatory T cells in the mouse hypothalamus control immune activation and ameliorate metabolic impairments in high-calorie environments.
2025 Scientific Article in Zeitschrift für Medizinische Physik Z. Med. Phys., DOI: 10.1016/j.zemedi.2025.02.005 (2025)
Refining visceral adipose tissue quantification: Influence of sex, age, and BMI on single slice estimation in 3D MRI of the German National Cohort.
2025 Scientific Article in Frontiers in Immunology Front. Immunol. 16:1559326 (2025)
Association of overweight/obesity and insulin resistance with activation of circulating innate lymphoid cells in women after gestational diabetes mellitus.
2025 Scientific Article in Nature metabolism Nat. Metab. 7, 574-585 (2025)
Non-caloric sweetener effects on brain appetite regulation in individuals across varying body weights.
2025 Scientific Article in Circulation Circulation, DOI: 10.1161/CIRCULATIONAHA.125.074545 (2025)
Oral semaglutide and cardiovascular outcomes in persons with type 2 diabetes, according to SGLT2i use: Prespecified analyses of the SOUL randomized trial.
2025 Scientific Article in Clinical Laboratory Clin. Lab. 71, 493-501 (2025)
Evaluation of the sysmex CN-6000 coagulation analyzer for routine and specialized coagulation testing in a central laboratory.
2025 Scientific Article in Nature Communications Nat. Commun. 16:2810 (2025)
Dependence of mitochondrial calcium signalling and dynamics on the disaggregase, CLPB.
2025 Scientific Article in Molecular Metabolism Mol. Metab.:102124 (2025)
A GLP-1 analogue optimized for cAMP-biased signaling improves weight loss in obese mice.
2025 Scientific Article in Molecular Metabolism Mol. Metab. 96:102129 (2025)
A once-daily GLP-1/GIP/glucagon receptor tri-agonist (NN1706) lowers body weight in rodents, monkeys and humans.
2025 Position paper in Diabetologie, Die Diabetologie, DOI: 10.1007/s11428-025-01304-2 (2025)
Geschlechtersensible Aspekte von Diabetes mellitus Typ 2.Präzisionsmedizin der Zukunft in der Diabetologie.
2025 Scandinavian journal of medicine & science in sports Scand. J. Med. Sci. Sports 35:e70051 (2025)
The metabolic fingerprint of cardiorespiratory fitness (vol 35, e70034, 2025).
2025 Review in Diabetes, Obesity and Metabolism Diabetes Obes. Metab. 27, 2, 3-19 (2025)
An overview of obesity-related complications: The epidemiological evidence linking body weight and other markers of obesity to adverse health outcomes.
2025 Scientific Article in Scientific Reports Sci. Rep. 15:8381 (2025)
Type of diet has no major influence on inflammatory response in a Saddleback pig model.
2025 Scientific Article in Diabetes, Stoffwechsel und Herz Diabetes Stoffwechs. Herz 34, accepted (2025)
Adipositas in der Regelversorgung – das neue DMP.
2025 Scientific Article in Diabetologia Diabetologia, DOI: 10.1007/s00125-025-06384-9 (2025)
Enterovirus VP1 protein and HLA class I hyperexpression in pancreatic islet cells of organ donors with type 1 diabetes.
2025 Scientific Article in Diabetologia Diabetologia, DOI: 10.1007/s00125-025-06401-x (2025)
Joint analysis of the nPOD-Virus Group data: The association of enterovirus with type 1 diabetes is supported by multiple markers of infection in pancreas tissue.
2025 Scientific Article in Nature Communications Nat. Commun. 16:2297 (2025)
An atypical atherogenic chemokine that promotes advanced atherosclerosis and hepatic lipogenesis.
2025 Scientific Article in Diabetes Diabetes, DOI: 10.2337/db24-0814 (2025)
A comparative analysis of the sensitivity, specificity, concordance, and the 5-year predictive power of diabetes-related autoantibody assays.
2025 Scientific Article in Clinical Journal of the American Society of Nephrology Clin. J. Am. Soc. Nephrol., DOI: 10.2215/CJN.0000000700 (2025)
Finerenone and clinical outcomes in chronic kidney disease and type 2 diabetes by frailty Iidex: FIDELITY post hoc analysis.
2025 Scientific Article in Nature metabolism Nat. Metab. 7, 602–616 (2025)
Dietary protein restriction elevates FGF21 levels and energy requirements to maintain body weight in lean men.
2025 Scientific Article in Stem Cell Research Stem Cell Res. 84:103685 (2025)
Generation of ARX-T2A-H2B-CFP x C-PEP-mCherry-hiPSC double reporter line for monitoring of pancreatic differentiation.
2025 Review in Molecular Metabolism Mol. Metab. 95:102118 (2025)
Glucose-dependent insulinotropic polypeptide (GIP).
2025 Scientific Article in Cellular and Molecular Gastroenterology and Hepatology Cell. Mol. Gast. Hept. 19:101485 (2025)
Therapeutic potential of STE20-type kinase STK25 inhibition for the prevention and treatment of metabolically induced hepatocellular carcinoma.
2025 Scientific Article in Metabolism: clinical and experimental Metabolism 167:156174 (2025)
Differential risk assessment in persons at risk of type 2 diabetes using urinary peptidomics.
2025 Editorial in Lancet Diabetes and Endocrinology Lancet Diabet. Endocrinol. 13, 265-267 (2025)
Bodyweight loss and remission of type 2 diabetes.
2025 Scientific Article in International Journal of Biological Macromolecules Int. J. Biol. Macromol. 306:141602 (2025)
Targeting Matrix Metalloproteinase-1, Matrix Metalloproteinase-7, and Serine Protease Inhibitor E1: Implications in preserving lung vascular endothelial integrity and immune modulation in COVID-19.
2025 Scientific Article in Reproduction Reproduction, DOI: 10.1530/REP-25-0105 (2025)
Towards a kingdom of reproductive life - the core sperm proteome.
2025 Other: News Item in Nature Reviews - Gastroenterology & Hepatology Nat. Rev. Gastroenterol. Hepatol. 22, 226–227 (2025)
Clusters of metabolic dysfunction-associated steatotic liver disease for precision medicine.
2025 Review in Hormone Research in Paediatrics Horm. Res. Paediatr., DOI: 10.1159/000543467 (2025)
Epigenetics of childhood obesity.
2025 Editorial in Journal of Steroid Biochemistry and Molecular Biology, The J. Steroid Biochem. Mol. Biol. 249:106715 (2025)
Facing challenges in modern steroid research.
2025 Scientific Article in STAR Protocols STAR Protoc. 6:103774 (2025)
Protocol for in vivo assessment of glucose control and insulin secretion and sensitivity in the pig.
2025 Scientific Article in Diabetes, Obesity and Metabolism Diabetes Obes. Metab. 27, 2626-2636 (2025)
Machine learning approach on plasma proteomics identifies signatures associated with obesity in the KORA FF4 cohort.
2025 Scientific Article in Cell Metabolism Cell Metab. 37, 566-569 (2025)
adiposetissue.org: A knowledge portal integrating clinical and experimental data from human adipose tissue.
2025 Scientific Article in Nature Communications Nat. Commun. 16:1958 (2025)
KAT6B overexpression rescues embryonic lethality in homozygous null KAT6A mice restoring vitality and normal lifespan.
2025 Scientific Article in Nature metabolism Nat. Metab. 7, 469-477 (2025)
A short-term, high-caloric diet has prolonged effects on brain insulin action in men.
2025 Scientific Article in Sleep Sleep:zsaf042 (2025)
Regulation of peripheral glucose levels during human sleep.
2025 Nature Communications Nat. Commun. 16:1911 (2025)
Author Correction: Targeting pleuro-alveolar junctions reverses lung fibrosis in mice.
2025 BMC Medicine BMC Med. 23:92 (2025)
Correction: Visceral adipose tissue area and proportion provide distinct reflections of cardiometabolic outcomes in weight loss; pooled analysis of MRI-assessed CENTRAL and DIRECT PLUS dietary randomized controlled trials.
2025 Scientific Article in Journal of Cachexia, Sarcopenia and Muscle J. Cachexia Sarcopenia Muscle 16:e13742 (2025)
Cachexia alters central nervous system morphology and functionality in cancer patients.
2025 Editorial in Nature metabolism Nat. Metab., DOI: 10.1038/s42255-025-01222-z (2025)
Intergenerational metabolic effects of cold exposure.
2025 Scientific Article in Science Advances Sci. Adv. 11:eadp8093 (2025)
Loss of Ten1 in mice induces telomere shortening and models human dyskeratosis congenita.
2025 Scientific Article in Nature Communications Nat. Commun. 16:3278 (2025)
LEOPARD: Missing view completion for multi-timepoint omics data via representation disentanglement and temporal knowledge transfer.
2025 Scientific Article in Obesity Science and Practice OBES. SCI. PRACT. 11:e70058 (2025)
Normal-weight offspring of parents with diet-induced obesity display altered gene expression profiles.
2025 Scientific Article in Contemporary clinical trials communications Contemp. Clin. Trails Comm. 44:101405 (2025)
Structures and strategies for retaining an international pediatric cohort from birth: Lessons from The Environmental Determinants of Diabetes in the Young (TEDDY) study.
2025 Review in Trends in Endocrinology and Metabolism Trends Endocrinol. Metab., DOI: 10.1016/j.tem.2025.01.004 (2025)
Prediabetes remission to reduce the global burden of type 2 diabetes.
2025 Scientific Article in Cell Death & Disease Cell Death Dis. 16:99 (2025)
Creatine transporter (SLC6A8) knockout mice exhibit reduced muscle performance, disrupted mitochondrial Ca2+ homeostasis, and severe muscle atrophy.
2025 Scientific Article in Nature Communications Nat. Commun. 16:173 (2025)
Targeting pleuro-alveolar junctions reverses lung fibrosis in mice.
2025 Letter to the Editor in Diabetologia Diabetologia 68, 892–895 (2025)
Considerations for more actionable consensus guidance for monitoring individuals with islet autoantibody-positive pre-stage 3 type 1 diabetes. Reply to Mallone R [letter].
2025 Scientific Article in Neurobiology of Learning and Memory Neurobiol. Learn. Mem. 218:108034 (2025)
The effect of fasting on human memory consolidation.
2025 Scientific Article in Clinical Epigenetics Clin. Epigenet. 17:21 (2025)
Sex-specific role of epigenetic modification of a leptin upstream enhancer in adipose tissue.
2025 Scientific Article in Endocrine Endocrine, DOI: 10.1007/s12020-025-04186-y (2025)
Expanding the phenotype of multiple endocrine neoplasia type 5 (MEN5): Pituitary gigantism, myelolipoma and familial pheochromocytoma due to a germline pathogenic MAX variant.
2025 Review in Diabetes, Obesity and Metabolism Diabetes Obes. Metab., DOI: 10.1111/dom.16247 (2025)
Novel pharmacotherapies for weight loss: Understanding the role of incretins to enable weight loss and improved health outcomes.
2025 Editorial in Nature metabolism Nat. Metab. 7, 247-248 (2025)
A future without needles: Non-invasive glucose measurements in patients with diabetes.
2025 Editorial in Nature Cell Biology Nat. Cell Biol. 27, 169-174 (2025)
Time for lipid cell biology.
2025 Other: Opinion in Trends in Endocrinology and Metabolism Trends Endocrinol. Metab., DOI: 10.1016/j.tem.2024.12.009 (2025)
Widening research horizons on metabolic dysfunction-associated steatotic liver disease and cancer.
2025 Scientific Article in Adipocyte Adipocyte 14:2468275 (2025)
Effects of alpelisib treatment on murine Pten-deficient lipomas.
2025 Scientific Article in BMC Medicine BMC Med. 23:57 (2025)
Visceral adipose tissue area and proportion provide distinct reflections of cardiometabolic outcomes in weight loss; pooled analysis of MRI-assessed CENTRAL and DIRECT PLUS dietary randomized controlled trials.
2025 Scientific Article in BMJ Open BMJ Open 15:e087982 (2025)
Sex hormone-dependent host-microbiome interactions and cardiovascular risk (XCVD): Design of a longitudinal multi-omics cohort study.
2025 Scientific Article in Environment International Environ. Int. 196:109306 (2025)
Metabolic and molecular Characterization, following dietary exposure to DINCH, Reveals new Implications for its role as a Metabolism-Disrupting chemical.
2025 Scientific Article in Journal of Cell Science J. Cell Sci. 138:JCS263438 (2025)
Clearing the path for whole-mount labeling and quantification of neuron- and vessel-density in adipose tissue.
2025 Scientific Article in Clinical Neuroradiology Clin. Neuroradiol., DOI: 10.1007/s00062-024-01493-1 (2025)
Intradermal advanced glycation end-products relate to reduced sciatic nerve structural integrity in type 2 diabetes.
2025 Scientific Article in Contemporary clinical trials communications Contemp. Clin. Trails Comm. 44:101434 (2025)
Anti-viral action against type 1 diabetes autoimmunity: The GPPAD-AVAnT1A study protocol.
2025 Review in Nature Chemical Biology Nat. Chem. Biol., DOI: 10.1038/s41589-024-01822-y (2025)
Mechanistic insights and approaches for beta cell regeneration.
2025 Review in Journal of the Endocrine Society J. Endocr. Soc. 9:bvaf006 (2025)
Circulating cell-free DNA in metabolic diseases.
2025 Scientific Article in Nature Genetics Nat. Genet. 57, 413-426 (2025)
Human subcutaneous and visceral adipocyte atlases uncover classical and nonclassical adipocytes and depot-specific patterns.
2025 Scientific Article in Nutrients Nutrients 17:3414 (2025)
Effect of a novel food rich in miraculin on the intestinal microbiome of malnourished patients with cancer and dysgeusia.
2025 Scientific Article in Nature Nature 638, 1065–1075 (2025)
Mapping cells through time and space with moscot.
2025 Scientific Article in Cell Reports Cell Rep. 44:115225 (2025)
Chronic intermittent fasting impairs β cell maturation and function in adolescent mice.
2025 Scientific Article in Science Science 387, 406-412 (2025)
A single gene orchestrates androgen variation underlying male mating morphs in ruffs.
2025 Position paper in Diabetologie, Die Diabetologie 21, 45-56 (2025)
Definition, Klassifikation, Diagnostik und Differenzialdiagnostik des Diabetes mellitus: Update 2024.
2025 Scientific Article in Diabetes Care Diabetes Care 48, 405-415 (2025)
Proteomic and metabolomic signatures in prediabetes progressing to diabetes or reversing to normoglycemia within 1 Year.
2025 Scientific Article in Langenbeck's Archives of Surgery Langenbecks Arch. Surg. 410:36 (2025)
A hypocaloric protein-rich diet before metabolic surgery improves liver function in patients with obesity and diabetes : A secondary analysis of a randomized clinical trial.
2025 Scientific Article in BMC Nutrition BMC Nut. 11, 8:8 (2025)
Investigating the impact of microbiome-changing interventions on food decision-making: MIFOOD study protocol.
2025 Review in Lancet Diabetes and Endocrinology Lancet Diabet. Endocrinol. 13, 221-262 (2025)
Definition and diagnostic criteria of clinical obesity.
2025 Scientific Article in European Journal of Endocrinology Eur. J. Endocrinol. 192, 46-60 (2025)
Impact of sex hormones on pheochromocytomas, paragangliomas, and gastroenteropancreatic neuroendocrine tumors.
2025 Review in Mammalian Genome Mamm. Genome, DOI: 10.1007/s00335-025-10104-4 (2025)
IMPC impact on preclinical mouse models.
2025 Scientific Article in Molecular Metabolism Mol. Metab. 95:102121 (2025)
Glucagon-like peptide-2 pharmacotherapy activates hepatic Farnesoid X receptor-signaling to attenuate resection-associated bile acid loss in mice.
2025 Scientific Article in Scientific Reports Sci. Rep. 15:1263 (2025)
Effects of time-of-day on the noradrenaline, adrenaline, cortisol and blood lipidome response to an ice bath.
2025 Scientific Article in BMJ Open BMJ Open 15:e088522 (2025)
EDENT1FI Master Protocol for screening of presymptomatic early-stage type 1 diabetes in children and adolescents.
2025 Scientific Article in Journal of Nephrology J. Nephrol. 38, 707-716 (2025)
Comparison of GFR estimation in patients with diabetes mellitus using the EKFC and CKD-EPI equations.
2025 Scientific Article in Journal of Translational Medicine J. Transl. Med. 23:7 (2025)
Weight cycling exacerbates glucose intolerance and hepatic triglyceride storage in mice with a history of chronic high fat diet exposure.
2025 Scientific Article in NeuroImage - a Journal of Brain Function Neuroimage 310:121154 (2025)
Influence of insulin sensitivity on food cue evoked functional brain connectivity in children.
2025 Scientific Article in Nature Communications Nat. Commun. 16:345 (2025)
Pantothenate kinase 4 controls skeletal muscle substrate metabolism.
2025 Scientific Article in Scandinavian journal of medicine & science in sports Scand. J. Med. Sci. Sports 35:e70034 (2025)
The metabolic signature of cardiorespiratory fitness.
2025 Scientific Article in Scientific Reports Sci. Rep. 15:2132 (2025)
Contribution of hypoxia-inducible factor 1alpha to pathogenesis of sarcomeric hypertrophic cardiomyopathy.
2025 Scientific Article in Proteomics - Clinical Applications Proteomics Clin. Appl. 19:e202400095 (2025)
Systemic changes in early pregnancy in the mare: An integrated proteomic analysis of blood plasma, histotroph, and yolk sac fluid at day 14 post-ovulation.
2025 Scientific Article in BMC Genomics BMC Genomics 26:48 (2025)
Systematic ocular phenotyping of 8,707 knockout mouse lines identifies genes associated with abnormal corneal phenotypes.
2025 Scientific Article in Nature Communications Nat. Commun. 16:1910 (2025)
Individual bioenergetic capacity as a potential source of resilience to Alzheimer's disease.
2025 Scientific Article in Metabolism: clinical and experimental Metabolism 164:156130 (2025)
Subphenotypes of body composition and their association with cardiometabolic risk - Magnetic resonance imaging in a population-based sample.
2025 Scientific Article in Kidney international reports Kidney Int. Rep. 10, 730-742 (2025)
GFR is a key determinant of red blood cell survival in anemia associated with progressive CKD.
2025 Scientific Article in International Journal of Molecular Sciences Int. J. Mol. Sci. 26:117 (2025)
Hypoxia regulates brown adipocyte differentiation and stimulates miR-210 by HIF-1α.
2025 Review in Lancet Diabetes and Endocrinology Lancet Diabet. Endocrinol. 13, 134-148 (2025)
Metabolic dysfunction-associated steatotic liver disease: heterogeneous pathomechanisms and effectiveness of metabolism-based treatment.
2025 Scientific Article in Lancet Diabetes and Endocrinology Lancet Diabet. Endocrinol. 13, 10-12 (2025)
Dysglycaemia definitions and progression to clinical type 1 diabetes in children with multiple islet autoantibodies.
2025 Scientific Article in Molecular Metabolism Mol. Metab. 91:102067 (2025)
Incretin-responsive human pancreatic adipose tissue organoids: A functional model for fatty pancreas research.
2025 Scientific Article in Nucleic Acids Research Nucleic Acids Res. 53, D651-D657 (2025)
CORUM in 2024: Protein complexes as drug targets.
2025 Scientific Article in Journal of Hepatology J. Hepatol. 82, 18-27 (2025)
Induction of steatosis in primary human hepatocytes recapitulates key pathophysiological aspects of metabolic dysfunction-associated steatotic liver disease.
2024 Position paper in Hormone Research in Paediatrics Horm. Res. Paediatr., DOI: 10.1159/000543035 (2024)
ISPAD clinical practice consensus guidelines 2024: Screening, staging, and strategies to preserve beta-cell function in children and adolescents with Type 1 Diabetes.
2024 Other: News Item in Nephrologie Aktuell Nephrol. Akt. 28, 156-161 (2024)
Update Kontraindikationen Peritonealdialyse. Ansätze zur Überwindung relativer Kontraindikationen.
2024 Other: News Item in Nephrologie Aktuell Nephrol. Akt. 28, 156-161 (2024)
Update Kontraindikationen Peritonealdialyse. Ansätze zur Überwindung relativer Kontraindikationen.
2024 Review in Endocrine Oncology Endocr. Oncol. 4:e240055 (2024)
NET Models Meeting 2024 white paper: The current state of neuroendocrine tumour research models and our future aspirations.
2024 Scientific Article in Neuroendocrinology Neuroendocrinology, DOI: 10.1159/000543136 (2024)
The novel SSTR3 full agonist ITF2984 shows antitumor properties against pancreatic neuroendocrine tumors (Pan-NETs).
2024 Scientific Article in Current Biology Curr. Biol. 34, 5822-5832.e5 (2024)
Doublecortin reinforces microtubules to promote growth cone advance in soft environments.
2024 Scientific Article in Nature Mental Health Nat. Ment. Health 2:27 (2024)
Sex differences in prenatal development of neural complexity in the human brain.
2024 Review in Journal of Obesity and Metabolic Syndrome J. Obes. Metab. Syndr. 33, 275-288 (2024)
Understanding adipose tissue dysfunction.
2024 Review in Frontiers in Neuroendocrinology Front Neuroendocrinol 77:101174 (2024)
"Estrogens and human brain networks: A systematic review of structural and functional neuroimaging studies".
Proceedings of SPIE In: (15th SPIE Conference on Developments in X-Ray Tomography, 19-22 August 2024, San Diego). 2024.:1315205 (Proc. SPIE ; 13152)
Development of a H&E multi-agent-staining method for laboratory-microCT applied to endocrine glands of MENX rats.
In: (EPiC Series in Computing). 2024. 51-83 ( ; 104)
Computational and analytical approaches for DNA methylation pattern modeling.
2024 Scientific Article in Obesity Facts Obes. Facts 18, 121-129 (2024)
Omentin increases glucose uptake, but not insulin sensitivity in human myotubes dependent on extracellular lactotransferrin.
2024 Scientific Article in SLEEP Advances SLEEP Adv. 5:zpae088 (2024)
The influence of intentions on dream content.
2024 Review in The Lancet Regional Health - Europe Lancet Reg. Health-Eur. 47:101098 (2024)
Why are we still in need for novel anti-obesity medications?
2024 Scientific Article in Molecular Metabolism Mol. Metab. 92:102091 (2024)
SF1-specific deletion of the energy sensor AMPKγ2 induces obesity.
2024 Scientific Article in Frontiers in Immunology Front. Immunol. 15:1428054 (2024)
Sex-dependent modulation of T and NK cells and gut microbiome by low sodium diet in patients with primary aldosteronism.
In: (IEEE Conference on Computer Vision and Pattern Recognition, 16-22 June 2024, Seattle, WA). 10662 Los Vaqueros Circle, Po Box 3014, Los Alamitos, Ca 90720-1264 Usa: Ieee Computer Soc, 2024. 3480-3490
HIT: Estimating internal human implicit tissues from the body surface.
2024 Scientific Article in Molecular Metabolism Mol. Metab. 79:101840 (2024)
Hypothalamic free fatty acid receptor-1 regulates whole-body energy balance.
2024 Letter to the Editor in Cell Research Cell Res. 35, 239-240 (2024)
Tug of war between phosphatase and kinase during sleep.
2024 Scientific Article in PLoS ONE PLoS ONE 19:e0315892 (2024)
Sodium butyrate is incorporated into central metabolism in fly head while inducing oxygen consumption increase.
2024 Scientific Article in Cell Metabolism Cell Metab. 37, 640-655.e4 (2024)
Unveiling adipose populations linked to metabolic health in obesity.
2024 Review in Frontiers in cell and developmental biology Front. Cell Dev. Biol. 12:1520783 (2024)
Paternal impact on the developmental programming of sexual dimorphism.
2024 Scientific Article in iScience iScience 27:110908 (2024)
Quiescence and aging of melanocyte stem cells and a novel association with programmed death-ligand 1.
2024 Scientific Article in Communications Medicine Commun. Med. 4:265 (2024)
Interpretable multimodal machine learning (IMML) framework reveals pathological signatures of distal sensorimotor polyneuropathy.
2024 Position paper in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 19, 414-425 (2024)
Methoden zur Abschätzung der Insulinresistenz.
2024 Editorial in Nature Reviews - Endocrinology Nat. Rev. Endocrinol. 21, 71-72 (2024)
Advances in appetite regulation by the arcuate nucleus.
2024 Scientific Article in Nature biomedical engineering Nat. Bio. Eng., DOI: 10.1038/s41551-024-01273-9 (2024)
Heterogeneity-driven phenotypic plasticity and treatment response in branched-organoid models of pancreatic ductal adenocarcinoma.
2024 Scientific Article in Cell Metabolism Cell Metab. 36, 2207–2227 (2024)
m6A mRNA methylation in brown fat regulates systemic insulin sensitivity via an inter-organ prostaglandin signaling axis independent of UCP1.
2024 Editorial in Circulation Circulation 150, 1910-1912 (2024)
Precision medicine in people at risk for diabetes and atherosclerotic cardiovascular disease: A fresh perspective on prevention.
2024 Position paper in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 19, S416-S426 (2024)
Recommendations for the nutritional prevention of type 2 diabetes mellitus.
2024 Position paper in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 19, S214-S225 (2024)
Gestational diabetes mellitus (GDM), diagnostics, therapy and aftercare.
2024 Position paper in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 19, S125-S137 (2024)
Definition, classification, diagnosis and differential diagnosis of diabetes mellitus: Update 2024.
2024 Position paper in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 19, S304-S308 (2024)
Diabetes mellitus and heart.
2024 Position paper in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 19, S297-S303 (2024)
Lipidtherapie bei Patienten mit Diabetes mellitus. Eine gemeinsame Stellungnahme der Kommission Fettstoffwechsel sowie der AG Diabetes und Herz der Deutschen Diabetes Gesellschaft (DDG), der Sektion Diabetes, Adipositas und Stoffwechsel der Deutschen Gesellschaft für Endokrinologie (DGE), der AG Herz und Diabetes der Deutschen Gesellschaft für Kardiologie (DGK) und der gemeinsamen AG Herz – Hormone – Diabetes der DGK, DGE und DDG.
2024 Position paper in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 19, S290-S296 (2024)
Diabetes and metabolic dysfunction-associated steatotic liver disease.
2024 Review in Diabetes, Stoffwechsel und Herz Diabetes Stoffwechs. Herz 33:74 (2024)
Early detection at different stages of type 1 diabetes.
2024 Editorial in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 19, S186-S202 (2024)
Therapy of type 2 diabetes.
2024 Scientific Article in Nature Communications Nat. Commun. 15:10631 (2024)
X-linked deletion of Crossfirre, Firre, and Dxz4 in vivo uncovers diverse phenotypes and combinatorial effects on autosomes.
2024 Scientific Article in International Journal of Obesity Int. J. Obes., DOI: 10.1038/s41366-024-01691-4 (2024)
Expression of p53 in human adipose tissue correlates positively with FAS and BMI.
2024 Review in Acta Paediatrica Acta Paediatr., DOI: 10.1111/apa.17449 (2024)
Markers of consciousness in infants: Towards a 'cluster-based' approach.
2024 Scientific Article in Cell Host & Microbe Cell Host Microbe 32, 2112-2130.e10 (2024)
Persistence of spike protein at the skull-meninges-brain axis may contribute to the neurological sequelae of COVID-19.
2024 Scientific Article in Molecular Psychiatry Mol. Psychiatry, DOI: 10.1038/s41380-024-02791-3 (2024)
Genetic and functional analyses of CTBP2 in anorexia nervosa and body weight regulation.
2024 Communications Medicine Commun. Med. 4:57 (2024)
Correction to: Genotype-stratified treatment for monogenic insulin resistance: a systematic review (Communications Medicine, (2023), 3, 1, (134), 10.1038/s43856-023-00368-9).
2024 Scientific Article in EBioMedicine EBioMedicine 110:105458 (2024)
FGF21 and its underlying adipose tissue-liver axis inform cardiometabolic burden and improvement in obesity after metabolic surgery.
2024 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab., DOI: 10.1210/clinem/dgae833 (2024)
Sex differences in insulin induced hippocampus functional connectivity during visual food cue presentation.
2024 Scientific Article in Cellular and Molecular Life Sciences - CMLS Cell. Mol. Life Sci. 81:468 (2024)
GLP-1 and GIP agonism has no direct actions in human hepatocytes or hepatic stellate cells.
2024 Scientific Article in Cell Reports Cell Rep. 43:114987 (2024)
Thyroid hormones are required for thermogenesis of beige adipocytes induced by Zfp423 inactivation.
2024 Review in The Lancet Regional Health - Europe Lancet Reg. Health-Eur. 47:101100 (2024)
Recent achievements and future directions of anti-obesity medications.
2024 Scientific Article in Nature metabolism Nat. Metab. 6, 2374–2390 (2024)
Inceptor binds to and directs insulin towards lysosomal degradation in β cells.
2024 Scientific Article in Clinical Nutrition Clin. Nutr. 43, 361-369 (2024)
Increase in PUFA and protein, and decrease in carbohydrate intake improves liver fat in 12 months and the role of weight loss as a mediator: A randomized controlled trial.
2024 Scientific Article in iScience iScience 27:111366 (2024)
Symmetric dimethylguanidino valeric acid, a novel single biomarker of hepatic steatosis.
2024 Scientific Article in International Journal of Eating Disorders Int. J. Eating Disord., DOI: 10.1002/eat.24338 (2024)
Dyadic psychopathology and adjustment to parenthood in families with and without eating disorder history-findings from a longitudinal study.
2024 Scientific Article in Nutrients Nutrients 16:3905 (2024)
Alterations in glucagon levels and the glucagon-to-insulin ratio in response to high dietary fat or protein intake in healthy lean adult twins: A post hoc analysis.
2024 Scientific Article in BMC Medicine BMC Med. 22:558 (2024)
Carrageenan and insulin resistance in humans: A randomised double-blind cross-over trial.
2024 Review in Nature metabolism Nat. Metab., DOI: 10.1038/s42255-024-01167-9 (2024)
Cancer cachexia: Multilevel metabolic dysfunction.
2024 Scientific Article in Nature Communications Nat. Commun. 15:9670 (2024)
Predictive learning shapes the representational geometry of the human brain.
2024 Scientific Article in Diabetologia Diabetologia, DOI: 10.1007/s00125-024-06301-6 (2024)
Transcriptomic heterogeneity of non-beta islet cells is associated with type 2 diabetes development in mouse models.
2024 Review in Disease Models and Mechanisms Dis. Model. Mech. 17:dmm050913 (2024)
Beyond genomic studies of congenital heart defects through systematic modelling and phenotyping.
2024 Scientific Article in Nature Nature 636, 457-465 (2024)
Adipose tissue retains an epigenetic memory of obesity after weight loss.
2024 Scientific Article in Cellular and Molecular Life Sciences - CMLS Cell. Mol. Life Sci. 81:458 (2024)
NFκB and JNK pathways mediate metabolic adaptation upon ESCRT-I deficiency.
2024 Review in Neuroscience Applied Neurosci. App. 3:104058 (2024)
Assessment of quality of life and wellbeing in mouse preclinical research – A scoping review.
2024 Scientific Article in Cardiovascular Diabetology Cardiovasc. Diabetol. 23:411 (2024)
The mediatory role of androgens on sex differences in glucose homeostasis and incidence of type 2 diabetes: The KORA study.
2024 Scientific Article in Proceedings of the National Academy of Sciences of the United States of America Proc. Natl. Acad. Sci. U.S.A. 121:e2409790121 (2024)
Subchronic elevation in ambient temperature drives alterations to the sperm epigenome and accelerates early embryonic development in mice.
2024 Scientific Article in Neuroscience Applied Neurosci. App. 3:104075 (2024)
Co-expression of prepulse inhibition and Schizophrenia genes in the mouse and human brain.
2024 Scientific Article in Gut Microbes Gut Microbes 16:2426610 (2024)
Gut microbial metabolism of bile acids modifies the effect of Mediterranean diet interventions on cardiometabolic risk in a randomized controlled trial.
2024 Scientific Article in Diabetes Diabetes 74, 65-74 (2024)
Exploring structural and molecular features of sciatic nerve lesions in diabetic neuropathy: Unveiling pathogenic pathways and targets.
2024 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 110, 1624-1632 (2024)
Discrimination and precision of Continuous Glucose Monitoring in staging children with presymptomatic type 1 diabetes.
2024 Scientific Article in Cancers Cancers 16:3414 (2024)
Effect of a novel food rich in miraculin on the oral microbiome of malnourished oncologic patients with dysgeusia.
2024 Scientific Article in Journal of Lipid Research J. Lipid Res. 65:100669 (2024)
GCKIII kinases control hepatocellular lipid homeostasis via shared mode of action.
2024 Scientific Article in Placenta Placenta 158, 126-135 (2024)
Gene expression profiles in placenta and their association with anesthesia, delivery mode and maternal diabetes.
2024 Scientific Article in Journal of the American Society of Nephrology J. Am. Soc. Nephrol., DOI: 10.1681/ASN.0000000521 (2024)
Transmembrane serine protease 2 and proteolytic activation of the epithelial sodium channel in mouse kidney.
2024 Scientific Article in Nephrology Dialysis Transplantation Nephrol. Dial. Transplant. 40, 929-942 (2024)
Noncanonical microglial IL-1β maturation in chronic kidney disease.
2024 Review in Nature Reviews - Endocrinology Nat. Rev. Endocrinol., DOI: 10.1038/s41574-024-01045-0 (2024)
Looking back at the TEDDY study: Lessons and future directions.
2024 Scientific Article in EMBO Journal, The EMBO J., DOI: 10.1038/s44318-024-00231-0 (2024)
TRPC5 controls the adrenaline-mediated counter regulation of hypoglycemia.
2024 Scientific Article in Cell Death and Differentiation Cell Death Differ., DOI: 10.1038/s41418-024-01398-z (2024)
Activating the NFE2L1-ubiquitin-proteasome system by DDI2 protects from ferroptosis.
2024 Review in Diabetes Diabetes 74:12-21 (2024)
Emerging concepts and success stories in type 1 diabetes research: A roadmap for a bright future.
2024 Scientific Article in Lancet Diabetes and Endocrinology Lancet Diabet. Endocrinol. 12, 890-903 (2024)
Depression symptoms, wellbeing, health-related quality of life, and diabetes-related distress in novel subtypes of recent-onset diabetes in Germany: A 5-year observational follow-up study.
2024 Scientific Article in ESC heart failure ESC Heart Fail., DOI: 10.1002/ehf2.15133 (2024)
Myocardial inflammation is associated with impaired mitochondrial oxidative capacity in ischaemic cardiomyopathy.
2024 Scientific Article in Clinical Nutrition Clin. Nutr. 43, 99-105 (2024)
The effect of active vitamin D supplementation on body weight and composition: A meta-analysis of individual participant data.
2024 Scientific Article in Nature Communications Nat. Commun. 15:8498 (2024)
Superior metabolic improvement of polycystic ovary syndrome traits after GLP1-based multi-agonist therapy.
2024 Scientific Article in Nutrients Nutrients 16:3045 (2024)
Efficacy and safety of the combination of palmitoylethanolamide, superoxide dismutase, alpha lipoic acid, vitamins B12, B1, B6, E, Mg, Zn and nicotinamide for 6 months in people with diabetic neuropathy.
2024 Scientific Article in American Journal of Clinical Nutrition Am. J. Clin. Nutr. 120, 1029-1036 (2024)
Glycemic control contributes to the neuroprotective effects of mediterranean and green-mediterranean diets on brain age; the DIRECT PLUS brain-MRI randomized controlled trial.
2024 Scientific Article in Scientific Reports Sci. Rep. 14:22286 (2024)
Expression of Intelectin-1, also known as Omentin-1, is related to clinical phenotypes such as overweight, obesity, insulin resistance, and changes after bariatric surgery.
2024 Scientific Article in Obesity Obesity 32, 1885-1896 (2024)
Functional redundancy between glucocorticoid and mineralocorticoid receptors in mature corticotropin-releasing hormone neurons protects from obesity.
2024 Scientific Article in JMIR Medical Informatics JMIR Med. Inf. 12:e52837 (2024)
Personalized prediction of long-term renal function prognosis following nUsing interpretable machine learning algorithms: Case-control study.
2024 Scientific Article in International Journal of Molecular Sciences Int. J. Mol. Sci. 25:11073 (2024)
Plasma lipidomics reveals lipid signatures of early pregnancy in mares.
2024 Letter to the Editor in Nature medicine Nat. Med., DOI: 10.1038/s41591-024-03292-0 (2024)
Time for a new framework that treats obesity in children as an adiposity-based chronic disease.
2024 Scientific Article in EMBO Journal, The EMBO J., DOI: 10.1038/s44318-024-00215-0 (2024)
IF1 is a cold-regulated switch of ATP synthase hydrolytic activity to support thermogenesis in brown fat.
2024 Scientific Article in Scientific Reports Sci. Rep. 14:25463 (2024)
Risk of celiac disease autoimmunity is modified by interactions between CD247 and environmental exposures.
2024 Editorial in Journal of Magnetic Resonance Imaging J. Magn. Reson. Imaging, DOI: 10.1002/jmri.29643 (2024)
Editorial for "MR elastography for classification of focal liver lesions using viscoelastic parameters: A pilot study based on intrinsic and extrinsic activations".
2024 Review in Cell Metabolism Cell Metab. 36, 2173-2189 (2024)
GLP-1 programs the neurovascular landscape.
2024 Review in Genetica Genetica, DOI: 10.1007/s10709-024-00216-1 (2024)
A "poly-matter network" conception of biological inheritance.
2024 Scientific Article in EMBO Journal, The EMBO J., DOI: 10.1038/s44318-024-00219-w (2024)
Systematic mapping of mitochondrial calcium uniporter channel (MCUC)-mediated calcium signaling networks.
2024 Scientific Article in Scientific Data Sci. Data 11:1159 (2024)
The Journey to a FAIR CORE DATA SET for Diabetes Research in Germany.
2024 Scientific Article in Journal of Bioenergetics and Biomembranes J. Bioenerg. Biomembr. 56, 483–493 (2024)
Reduction in mitochondrial ATP synthesis mimics the effect of low glucose in depolarizing neurons from the subpostremal nucleus of the solitary tract of rats.
2024 Scientific Article in Diabetologia Diabetologia, DOI: 10.1007/s00125-024-06275-5 (2024)
Quantitative analysis of islet prohormone convertase 1/3 expression in human pancreas donors with diabetes.
2024 Review in Circulation Circulation 150, 1288-1298 (2024)
Muscle mass and glucagon-like peptide-1 receptor agonists: Adaptive or maladaptive response to weight loss?
2024 Scientific Article in Diabetes, Obesity and Metabolism Diabetes Obes. Metab., DOI: 10.1111/dom.15930 (2024)
Trends in pharmacological management of paediatric patients with type 2 diabetes from 2000 to 2023 in German-speaking countries: Analysis based on the Diabetes Prospective Follow-up Registry.
2024 Diabetologia Diabetologia 67, 2012–2014 (2024)
Correction to: Consensus guidance for monitoring individuals with islet autoantibody‑positive pre‑stage 3 type 1 diabetes.
2024 Scientific Article in Genes Genes 15:1059 (2024)
Effects of ACLY inhibition on body weight distribution: A drug target mendelian randomization study.
2024 Scientific Article in Food and Function Food Funct. 15, 9833-9848 (2024)
Differential effects of milk, yogurt, and cheese on energy homeostasis and brown adipose tissue phenotype in high-fat diet-induced obese mice.
2024 Cardiovascular Diabetology Cardiovasc. Diabetol. 23:341 (2024)
Correction: GIP receptor agonism improves dyslipidemia and atherosclerosis independently of body weight loss in preclinical mouse model for cardio-metabolic disease.
2024 Scientific Article in Nutrients Nutrients 16:2633 (2024)
The concentration of salivary extracellular vesicles is related to obesity.
2024 Scientific Article in International Journal of Molecular Sciences Int. J. Mol. Sci. 25:8823 (2024)
Temperature-dependent tRNA modifications in bacillales.
2024 Scientific Article in Nutrients Nutrients 16:2661 (2024)
Association of salty and sweet taste recognition with food reward and subjective control of eating behavior.
2024 Scientific Article in Molecular Metabolism Mol. Metab. 90:102033 (2024)
HDAC5 controls a hypothalamic STAT5b-TH axis, the sympathetic activation of ATP-consuming futile cycles and adult-onset obesity in male mice.
2024 Scientific Article in Metabolomics Metabolomics 20:109 (2024)
Infants with biliary atresia exhibit an altered amino acid profile in their newborn screening.
2024 Scientific Article in Advanced science Adv. Sci.:e2404661 (2024)
The eATP/P2×7R axis drives quantum dot-nanoparticle induced neutrophil recruitment in the pulmonary microcirculation.
2024 Scientific Article in Science Advances Sci. Adv. 10:eadl4374 (2024)
Loss of atrial natriuretic peptide signaling causes insulin resistance, mitochondrial dysfunction, and low endurance capacity.
2024 Position paper in European Heart Journal Eur. Heart J. 45, 4063–4098 (2024)
Obesity and cardiovascular disease: An ESC clinical consensus statement.
2024 Scientific Article in Nature Communications Nat. Commun. 15:7483 (2024)
Adipocyte deletion of the oxygen-sensor PHD2 sustains elevated energy expenditure at thermoneutrality.
2024 Letter to the Editor in Nature Reviews - Genetics Nat. Rev. Genet. 25:678 (2024)
The complex non-genetic inheritance of complex traits.
2024 Scientific Article in Biological Psychiatry Global Open Science Biol. Psychiatry Glob. Open. Sci. 4:100385 (2024)
Resilience to chronic stress is characterized by circadian brain-liver coordination.
2024 Scientific Article in International Journal of Obesity Int. J. Obes., DOI: 10.1038/s41366-024-01608-1 (2024)
Exposure to gestational diabetes mellitus in utero impacts hippocampal functional connectivity in response to food cues in children.
2024 Editorial in Diabetologie, Die Diabetologie 20, 711-713 (2024)
Typ 1 Diabetes in der Praxis.
2024 Scientific Article in Communications Medicine Commun. Med. 4:145 (2024)
Precision treatment of beta-cell monogenic diabetes: A systematic review.
2024 Scientific Article in Communications Medicine Commun. Med. 4:75 (2024)
Effective interventions in preventing gestational diabetes mellitus: A systematic review and meta-analysis.
2024 Scientific Article in Diabetologia Diabetologia 67, 2804-2818 (2024)
Role of human plasma metabolites in prediabetes and type 2 diabetes from the IMI-DIRECT study.
2024 Scientific Article in Molecular Metabolism Mol. Metab. 88:102014 (2024)
Picalm, a novel regulator of GLUT4-trafficking in adipose tissue.
2024 Scientific Article in Diabetes Care Diabetes Care 47, 1808-1817 (2024)
Clinical outcomes in pediatric patients with type 1 diabetes with early versus late diagnosis: Analysis from the DPV registry.
2024 Scientific Article in Cardiovascular Diabetology Cardiovasc. Diabetol. 23:306 (2024)
Blood coagulation in Prediabetes clusters-impact on all-cause mortality in individuals undergoing coronary angiography.
2024 Review in Metabolism: clinical and experimental Metabolism 160:156014 (2024)
Metabolic dysfunction-associated steatotic liver disease and extrahepatic gastrointestinal cancers.
2024 Scientific Article in Diabetes, Obesity and Metabolism Diabetes Obes. Metab. 26, 4713-4723 (2024)
The effect of Mankai plant consumption on postprandial glycaemic response among patients with type 2 diabetes: A randomized crossover trial.
2024 Scientific Article in Communications Biology Comm. Biol. 7:996 (2024)
ScreenDMT reveals DiHOMEs are replicably inversely associated with BMI and stimulate adipocyte calcium influx.
Methods in Molecular Biology In: Chromatin Immunoprecipitation. 2024. 35-45 (Methods Mol. Biol. ; 2846)
Chromatin immunoprecipitation in adipose tissue and adipocytes: How to proceed and optimize the protocol for transcription factor DNA binding.
2024 Scientific Article in Islets Islets 16:2392343 (2024)
Small RNA-Seq and real time rt-qPCR reveal islet miRNA released under stress conditions.
2024 Scientific Article in PLoS Biology PLoS Biol. 22:e3002768 (2024)
Slow-wave sleep drives sleep-dependent renormalization of synaptic AMPA receptor levels in the hypothalamus.
2024 Scientific Article in Journal of Clinical Medicine J. Clin. Med. 13:4528 (2024)
Antiphospholipid antibody testing in a maximum care hospital: Method-dependent differences.
2024 Scientific Article in Mammalian Genome Mamm. Genome 35, 544-550 (2024)
Digital tools of analysis and data integration facilitate synergy between mouse and human brain research and enable translation.
2024 Scientific Article in Diabetes, Obesity and Metabolism Diabetes Obes. Metab. 26, 4562-4570 (2024)
Oxytocin does not acutely improve glucose tolerance in men with type 2 diabetes.
2024 Scientific Article in Science Advances Sci. Adv. 10:eadp6182 (2024)
Integrated single-cell RNA-seq analysis reveals mitochondrial calcium signaling as a modulator of endothelial-to-mesenchymal transition.
2024 Scientific Article in Metabolomics Metabolomics 20:105 (2024)
Stool and blood metabolomics in the metabolic syndrome: A cross-sectional study.
2024 Scientific Article in Nature Neuroscience Nat. Neurosci. 27, 1758-1773 (2024)
A GnRH neuronal population in the olfactory bulb translates socially relevant odors into reproductive behavior in male mice.
In: (41st International Conference on Machine Learning, 21-27 July 2024, Vienna). 2024. 61897-61912 ( ; 235)
MultiMax: Sparse and multi-modal attention learning.
2024 Scientific Article in Kidney International Kidney Int. 106, 1101-1116 (2024)
Chronic kidney disease leads to microglial potassium efflux and inflammasome activation in the brain.
2024 Review in Journal of Endocrinology J. Endocrinol. 262:e240115 (2024)
The role of adipose tissue dysfunction in hepatic insulin resistance and T2D.
2024 Scientific Article in Science Advances Sci. Adv. 10:eadp0443 (2024)
Opa1 processing is dispensable in mouse development but is protective in mitochondrial cardiomyopathy.
2024 Scientific Article in Life Science Alliance Life Sci. All. 7:e202402771 (2024)
Examining the liver-pancreas crosstalk reveals a role for the molybdenum cofactor in β-cell regeneration.
2024 Acta Diabetologica Acta Diabetol. 61, 1015-1015 (2024)
Correction: GALNT2 expression is associated with glucose control and serum metabolites in patients with type 2 diabetes.
2024 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 110, e1451-e1457 (2024)
GFR decline predicts total mortality and mediates the effect of tryptophan metabolism on death risk in type 2 diabetes.
2024 Scientific Article in Nature Communications Nat. Commun. 15:7111 (2024)
A roadmap to the molecular human linking multiomics with population traits and diabetes subtypes.
2024 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 110, e1323-e1333 (2024)
Inflammation and prediction of death in type 2 diabetes. Evidence of an intertwined link with tryptophan metabolism.
2024 Scientific Article in Acta Diabetologica Acta Diabetol. 61, 1007-1013 (2024)
GALNT2 expression is associated with glucose control and serum metabolites in patients with type 2 diabetes.
Lecture Notes in Computer Science In: (Medical Image Understanding and Analysis). Gewerbestrasse 11, Cham, Ch-6330, Switzerland: Springer International Publishing Ag, 2024. 366-381 (Lect. Notes Comput. Sc. ; 14860 LNCS)
EchoVisuAL: Efficient Segmentation of Echocardiograms Using Deep Active Learning.
2024 Scientific Article in Cell Metabolism Cell Metab. 36, DOI: 10.1016/j.cmet.2024.07.005 (2024)
Single-nucleus transcriptomics identifies separate classes of UCP1 and futile cycle adipocytes.
2024 Scientific Article in Reproduction, Fertility and Development Reprod. Fertil. Dev. 36:RD24079 (2024)
ShinySperm: Navigating the sperm proteome landscape.
2024 Scientific Article in European Journal of Vascular and Endovascular Surgery Eur. J. Vasc. Endovasc. Surg. 68, 641-651 (2024)
Ten year time trends of amputation surgery in peripheral arterial disease in Germany: Before and during the COVID-19 pandemic.
2024 Review in Diabetes, Obesity and Metabolism Diabetes Obes. Metab., DOI: 10.1111/dom.15796 (2024)
The role of incretin receptor agonists in the treatment of obesity.
2024 Scientific Article in Surgery Open Science Surg. Open Sci. 20, 194-202 (2024)
A novel latex patch model enables cost-effective hands-on teaching in vascular surgery.
2024 Scientific Article in Arthritis & Rheumatology Arthritis Rheum. 76, 1719-1729 (2024)
CD4+CD8αlow T cells in rheumatoid arthritis are clonally expanded and dependent on co-stimulation.
2024 Scientific Article in Frontiers in Immunology Front. Immunol. 15:1416543 (2024)
Dysregulated cytokine and oxidative response in hyper-glycolytic monocytes in obesity.
2024 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 110, 498-510 (2024)
Early appearance of thyroid autoimmunity in children followed from birth for type 1 diabetes risk.
2024 Scientific Article in Nutrients Nutrients 16:2089 (2024)
Effect of Crocus sativus extract supplementation in the metabolic control of people with diabetes mellitus type 1: A double-blind randomized placebo-controlled trial.
2024 Scientific Article in European Journal of Endocrinology Eur. J. Endocrinol. 191, 183-191 (2024)
Impact of peripheral thyroid hormone balance on liver fat: Insights from the NutriAct trial.
2024 Scientific Article in eLife eLife 12:RP92075 (2024)
Liver microRNA transcriptome reveals miR-182 as link between type 2 diabetes and fatty liver disease in obesity.
2024 Review in Nature Reviews - Endocrinology Nat. Rev. Endocrinol., DOI: 10.1038/s41574-024-01021-8 (2024)
The interactions between energy homeostasis and neurovascular plasticity.
2024 Scientific Article in Obesity Obesity, DOI: 10.1002/oby.24092 (2024)
Fas (CD95) expression in adipocytes contributes to diet-induced obesity.
2024 Scientific Article in Obesity Research and Clinical Practice Obes. Res. Clin. Pract. 18, 181-188 (2024)
Diurnal rythm of Nampt is gender and weight dependent.
2024 Scientific Article in Diabetes Diabetes 73, 1583-1591 (2024)
Autoantibodies to truncated GAD(96-585) antigen stratify risk of early insulin requirement in adult-onset diabetes.
2024 Scientific Article in STAR Protocols STAR Protoc. 5:103163 (2024)
Protocol for chromatin immunoprecipitation of histone modifications in frozen adipose tissue.
2024 Scientific Article in Journal of Cellular and Molecular Medicine J. Cell. Mol. Med. 28:e18272 (2024)
Development, synthesis and validation of improved c-Myc/Max inhibitors.
2024 Scientific Article in Transplant international Transpl. Int. 37:12879 (2024)
SGLT2 inhibitors correct fluid overload in adult kidney transplant recipients-A prospective observational study.
2024 Scientific Article in International Journal of Molecular Sciences Int. J. Mol. Sci. 25:6400 (2024)
IGF-1 and IGFBP-1 as possible predictors of response to lifestyle intervention-results from randomized controlled trials.
2024 Scientific Article in Diabetes, Obesity and Metabolism Diabetes Obes. Metab., DOI: 10.1111/dom.15728 (2024)
Changes in lean body mass with glucagon-like peptide-1-based therapies and mitigation strategies.
2024 Review in Cell Cell 187, 3829-3853 (2024)
Transforming obesity: The advancement of multi-receptor drugs.
2024 Scientific Article in Cell Reports Cell Rep. 43:114343 (2024)
GABAergic disinhibition from the BNST to PNOCARC neurons promotes HFD-induced hyperphagia.
2024 Scientific Article in iScience iScience 27:109711 (2024)
Unveiling the dynamics of acetylation and phosphorylation in SGBS and 3T3-L1 adipogenesis.
2024 Scientific Article in Journal of the Endocrine Society J. Endocr. Soc. 8:bvae103 (2024)
The influence of pubertal development on autoantibody appearance and progression to type 1 diabetes in the TEDDY Study.
2024 Scientific Article in Infection - A Journal of Infectious Disease Infection, DOI: 10.1007/s15010-024-02312-y (2024)
Infection episodes and islet autoantibodies in children at increased risk for type 1 diabetes before and during the COVID-19 pandemic.
2024 Scientific Article in Appetite Appetite 200:107551 (2024)
Mother-infant feeding interactions in mothers with and without eating disorder history: Results of a structured observational study.
2024 Scientific Article in Life Science Alliance Life Sci. All. 7:e202402828 (2024)
Mitochondrial lipidomes are tissue specific - low cholesterol contents relate to UCP1 activity.
2024 Scientific Article in Molecular Metabolism Mol. Metab. 87:101992 (2024)
Experimental colonization with H. hepaticus, S. aureus and R. pneumotropicus does not influence the metabolic response to high-fat diet or incretin-analogues in wildtype SOPF mice.
2024 Review in Monatsschrift Kinderheilkunde Mon.schr. Kinderheilkd., DOI: 10.1007/s00112-024-02009-4 (2024)
Deutsches Zentrum für Kinder- und Jugendgesundheit. Interdisziplinäre Forschung für eine gesunde Zukunft von Kindern und Jugendlichen.
2024 Scientific Article in Diabetes, Obesity and Metabolism Diabetes Obes. Metab., DOI: 10.1111/dom.15767 (2024)
Visceral fat mass dynamics in a 2-year randomized STrength versus ENdurance training trial in people with obesity.
2024 Scientific Article in BMJ Open Diabetes Research & Care BMJ Open Diab. Res. Care 12:e004256 (2024)
Surrogate measures of first-phase insulin secretion versus reference methods intravenous glucose tolerance test and hyperglycemic clamp: A systematic review and meta-analyses.
2024 Review in Trends in Endocrinology and Metabolism Trends Endocrinol. Metab. 35, 566-568 (2024)
Antagonizing GIPR adds fire to the GLP-1R flame.
2024 Scientific Article in iScience iScience 27:110368 (2024)
sNucConv: A bulk RNA-seq deconvolution method trained on single-nucleus RNA-seq data to estimate cell-type composition of human adipose tissues.
2024 Scientific Article in Circulation Circulation 150, 1101-1120 (2024)
Novel long noncoding RNA HEAT4 affects monocyte subtypes, reducing inflammation and promoting vascular healing.
2024 Scientific Article in JAMA: Journal of the American Medical Association JAMA 332, 501-502 (2024)
Progression from presymptomatic to clinical type 1 diabetes after COVID-19 infection.
2024 Scientific Article in Insights into Imaging Insights Imaging 15:124 (2024)
Radiomics workflow definition & challenges - German priority program 2177 consensus statement on clinically applied radiomics.
2024 Scientific Article in Lancet Diabetes and Endocrinology Lancet Diabet. Endocrinol. 12, 514-515 (2024)
Impact of higher BMI on cardiometabolic risk: Does height matter?
2024 Review in Nature Reviews - Endocrinology Nat. Rev. Endocrinol., DOI: 10.1038/s41574-024-01008-5 (2024)
Metabolically healthy obesity: From epidemiology and mechanisms to clinical implications.
2024 Scientific Article in Nature metabolism Nat. Metab., DOI: 10.1038/s42255-024-01078-9 (2024)
PAQR4 regulates adipocyte function and systemic metabolic health by mediating ceramide levels.
2024 Scientific Article in Diabetologia Diabetologia, DOI: 10.1007/s00125-024-06176-7 (2024)
Caesarean section and risk of type 1 diabetes.
2024 Scientific Article in eLife eLife 12:31 (2024)
mitoBKCa is functionally expressed in murine and human breast cancer cells and potentially contributes to metabolic reprogramming.
2024 Scientific Article in Acta Physiologica Acta Physiol. 240:e14183 (2024)
Amiloride versus furosemide for the treatment of edema in patients with nephrotic syndrome: A pilot study (AMILOR).
2024 Scientific Article in EBioMedicine EBioMedicine 106:105242 (2024)
Blood methylation pattern reflects epigenetic remodelling in adipose tissue after bariatric surgery.
2024 Review in Nature metabolism Nat. Metab., DOI: 10.1038/s42255-024-01079-8 (2024)
Obesity-induced inflammation: Connecting the periphery to the brain.
2024 Scientific Article in Molecular and Cellular Proteomics Mol. Cell. Proteomics 23:100811 (2024)
Enhanced in situ spatial proteomics by effective combination of MALDI imaging and LC-MS/MS.
2024 Scientific Article in Diabetes Diabetes 73, 1361-1371 (2024)
An E115A missense variant in CERS2 is associated with increased sleeping energy expenditure and hepatic insulin resistance in American Indians.
2024 Scientific Article in Diabetologia Diabetologia, DOI: 10.1007/s00125-024-06178-5 (2024)
Role of weight loss-induced prediabetes remission in the prevention of type 2 diabetes: Time to improve diabetes prevention.
2024 Position paper in Diabetologie, Die Diabetologie 20, 80–91 (2024)
Definition, Klassifikation, Diagnostik und Differenzialdiagnostik des Diabetes mellitus: Update 2023.
2024 Position paper in Diabetes Aktuell Diabetes akt. 22, 98-102 (2024)
Diabetes mellitus und Herz. Notwendigkeit einer gezielten Risikostratifizierung und konsequenten Behandlung.
2024 Scientific Article in Studies in Higher Education Stud. High. Educ., DOI: 10.1080/03075079.2024.2364066 (2024)
Behind the scenes of doctoral success: A mixed methods approach to exploring PhD supervision courses in Swedish higher education institutions.
2024 Scientific Article in Photoacoustics Photoacoustics 38:100628 (2024)
Non-invasive optoacoustic imaging of dermal microcirculatory revascularization in diet-induced obese mice undergoing exercise intervention.
2024 Position paper in Diabetes Care Diabetes Care 47, 1276-1298 (2024)
Consensus guidance for monitoring individuals with islet autoantibody-positive pre-stage 3 type 1 diabetes.
2024 Scientific Article in Human Brain Mapping Hum. Brain Mapp. 45:e26752 (2024)
The interplay between white adipose tissue, adipokines, and structural gray matter changes.
2024 Scientific Article in Science Science 384, 1111-1117 (2024)
Two-stage evolution of mammalian adipose tissue thermogenesis.
2024 Scientific Article in Endocrinology Endocrinology 165:bqae067 (2024)
Comparative phenotyping of mice reveals canonical and noncanonical physiological functions of TRα and TRβ.
2024 Scientific Article in Postepy Biochemii Postepy Biochem. 70, 8-21 (2024)
Space-time dynamics of genome replication studied with super-resolved microscopy.
2024 Review in Nature Communications Nat. Commun. 15:5574 (2024)
Improving laboratory animal genetic reporting: LAG-R guidelines.
2024 Scientific Article in Pituitary Pituitary 27, 567-576 (2024)
Decreased β-cell volume and insulin secretion but preserved glucose tolerance in a growth hormone insensitive pig model.
2024 Scientific Article in European Journal of Epidemiology Eur. J. Epidemiol. 39, 915-924 (2024)
Sex hormone-binding globulin may explain sex differences for glucose homeostasis and incidence of type 2 diabetes: The KORA study.
2024 Scientific Article in Obesity Obesity, DOI: 10.1002/oby.24036 (2024)
Altered proteome profiles related to visceral adiposity may mediate the favorable effect of green Mediterranean diet: The DIRECT-PLUS trial.
2024 Scientific Article in Diabetes Care Diabetes Care 47, 1584-1592 (2024)
Glucose load following prolonged fasting increases oxidative stress-linked response in individuals with diabetic complications.
2024 Review in Redox Biology Redox Biol. 75:103211 (2024)
Ferroptosis in health and disease.
2024 Scientific Article in Molecular Metabolism Mol. Metab. 85:101956 (2024)
Sulfonylureas exert antidiabetic action on adipocytes by inhibition of PPARγ serine 273 phosphorylation.
2024 Scientific Article in BMC Medicine BMC Med. 22:259 (2024)
First-in-human, double-blind, randomized phase 1b study of peptide immunotherapy IMCY-0098 in new-onset type 1 diabetes: an exploratory analysis of immune biomarkers.
2024 Scientific Article in Magnetic Resonance Materials in Physics, Biology and Medicine Magn. Reson. Mater. Phys. Biol. Med., DOI: 10.1007/s10334-024-01166-7 (2024)
A straightforward procedure to build a non-toxic relaxometry phantom with desired T1 and T2 times at 3T.
2024 Scientific Article in Facial Plastic Surgery Facial Plast. Surg., DOI: 10.1055/s-0044-1786185 (2024)
Characterization of fat used for the optimization of the soft tissue envelope of the nose in rhinoplasty.
2024 Letter to the Editor in Signal transduction and targeted therapy Signal Transduct. Target. Ther. 9:147 (2024)
Cellular precision modulation of JAK1: Tailoring therapies for allergic lung inflammation.
2024 Scientific Article in CVIR Endovascular CVIR Endovasc. 7:42 (2024)
ELECT: Prospective, randomized trial comparing microvascular plug versus platinum-fibered microcoils for embolization of aneurysm sac side branches before endovascular aortic aneurysm repair.
2024 Scientific Article in Metabolites Metabolites 14:209 (2024)
Accumulation of non-pathological liver fat is associated with the loss of glyoxalase I activity in humans.
2024 Scientific Article in Brain, Behavior and Immunity Brain Behav. Immun. 52, 399-405 (2024)
Correlating maternal and cord-blood inflammatory markers and BDNF with human fetal brain activity recorded by magnetoencephalography: An exploratory study.
2024 Scientific Article in American Journal of Physiology - Cell Physiology Am. J. Physiol.-Cell Physiol. 326, C1462-C1481 (2024)
IGF1 promotes human myotube differentiation toward a mature metabolic and contractile phenotype.
2024 Scientific Article in Clinical Obesity Clin. Obes.:e12672 (2024)
Patients' perspective on their drug therapy after bariatric surgery: A quantitative, cross-sectional interview study.
2024 Scientific Article in Journal of Peptide Science J. Pept. Sci.:e3611 (2024)
Targeted modulation of gene expression through receptor-specific delivery of small interfering RNA peptide conjugates.
2024 Scientific Article in Cardiovascular Research Cardiovasc. Res. 120, 1411-1426 (2024)
Myeloid cannabinoid CB1 receptor deletion confers atheroprotection in male mice by reducing macrophage proliferation in a sex-dependent manner.
2024 Scientific Article in Diabetes Care Diabetes Care 47, 1424-1431 (2024)
Data-driven phenotyping of presymptomatic type 1 diabetes using longitudinal autoantibody profiles.
2024 Review in Trends in Endocrinology and Metabolism Trends Endocrinol. Metab. 36, 42-54 (2024)
Neuroendocrine gut-brain signaling in obesity.
2024 Scientific Article in Cardiovascular Diabetology Cardiovasc. Diabetol. 23:199 (2024)
Bidirectional modulation of TCA cycle metabolites and anaplerosis by metformin and its combination with SGLT2i.
2024 Editorial in Nature Reviews - Endocrinology Nat. Rev. Endocrinol., DOI: 10.1038/s41574-024-00996-8 (2024)
Prediabetes remission for type 2 diabetes mellitus prevention.
2024 Review in Cell calcium Cell Calcium 121:102907 (2024)
Unravelling the complexity of the mitochondrial Ca2+ uniporter: Regulation, tissue specificity, and physiological implications.
2024 Review in Nature Reviews - Endocrinology Nat. Rev. Endocrinol., DOI: 10.1038/s41574-024-00992-y (2024)
AMPK as a mediator of tissue preservation: Time for a shift in dogma?
2024 Scientific Article in Transplantation Reviews Transplant. Rev. 38:100856 (2024)
Immunosuppressive drug combinations after kidney transplantation and post-transplant diabetes: A systematic review and meta-analysis.
2024 Scientific Article in Nature Nature 638, 720-727 (2024)
Epigenetic inheritance of diet-induced and sperm-borne mitochondrial RNAs.
2024 Scientific Article in Nature Methods Nat. Methods, DOI: 10.1038/s41592-024-02245-2 (2024)
Virtual reality-empowered deep-learning analysis of brain cells.
2024 Position paper in Gesundheitswesen, Das Gesundheitswesen, DOI: 10.1055/a-2320-2859 (2024)
Früherkennung von Typ-1-Diabetes durch Inselautoantikörper-Screening – ein Positionspapier der Fr1daPlex-Projektleiter und -Schulungszentren, des BVKJ Bayern und PaedNetz Bayern e.V.
2024 Scientific Article in Scientific Reports Sci. Rep. 14:11341 (2024)
Network-targeted transcranial direct current stimulation of the hypothalamus appetite-control network: A feasibility study.
2024 Scientific Article in Signal transduction and targeted therapy Signal Transduct. Target. Ther. 9:103 (2024)
Dysfunction of the adhesion G protein-coupled receptor latrophilin 1 (ADGRL1/LPHN1) increases the risk of obesity.
2024 Review in Zeitschrift für Medizinische Ethik Z. Med. Eth. 70, 195-213 (2024)
Leitbilder und Forschung in der Geschlechtersensiblen Medizin.
2024 Scientific Article in JACC: Heart Failure JACC: Heart Fail. 12, 1778-1780 (2024)
Myocardial mitochondrial function is impaired in cardiac light-chain amyloidosis compared to transthyretin amyloidosis.
2024 Editorial in Frontiers in Endocrinology Front. Endocrin. 15:1371113 (2024)
Editorial: Novel and emerging therapies for the treatment of obesity and related disorders.
2024 Scientific Article in Lancet Diabetes and Endocrinology Lancet Diabet. Endocrinol. 12, 376-378 (2024)
Effect of population-wide screening for presymptomatic early-stage type 1 diabetes on paediatric clinical care.
2024 Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet. 132:e2 (2024)
Correction: Nutritional recommendations for the prevention of Type 2 Diabetes Mellitus.
2024 Editorial in Frontiers in Endocrinology Front. Endocrin. 15:1404839 (2024)
Editorial: Islet cell development, heterogeneity and regeneration.
2024 Letter to the Editor in Cell Stem Cell Cell Stem Cell 31, 793-794 (2024)
Greasing the machinery toward maturation of stem cell-derived β cells.
2024 Scientific Article in Journal of Hepatology J. Hepatol. 81, 479-491 (2024)
EMC10 modulates hepatic ER stress and steatosis in an isoform specific manner.
2024 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab., DOI: 10.1210/clinem/dgae241 (2024)
Opposing effects of cannabidiol in patient-derived neuroendocrine tumor, pheochromocytoma/paraganglioma primary cultures.
2024 Scientific Article in Scientific Reports Sci. Rep. 14:9057 (2024)
Comparing targeted memory reactivation during slow wave sleep and sleep stage 2.
2024 Review in Clinical Obesity Clin. Obes. 14:e12659 (2024)
IMPROVE 2022 International Meeting on pathway-related obesity: Vision of excellence.
2024 Scientific Article in Nature Communications Nat. Commun. 15:3740 (2024)
Acinar to β-like cell conversion through inhibition of focal adhesion kinase.
2024 Scientific Article in JBMR Plus JBMR Plus 8:ziae036 (2024)
MiR-144-5p and miR-21-5p do not drive bone disease in a mouse model of type 1 diabetes mellitus.
2024 Scientific Article in Nutrients Nutrients 16:1057 (2024)
Improvement in visceral adipose tissue and LDL cholesterol by high PUFA intake: 1-year results of the NutriAct trial.
2024 Review in Diabetes Therapy Diabetes Ther. 15, 1069-1084 (2024)
Dual and triple incretin-based co-agonists: Novel therapeutics for obesity and diabetes.
2024 Scientific Article in Thyroid Thyroid 34, 785-795 (2024)
Canonical and noncanonical contribution of thyroid hormone receptor isoforms alpha and beta to cardiac hypertrophy and heart rate in male mice.
2024 Scientific Article in Science Advances Sci. Adv. 10:eadj8769 (2024)
A brain-enriched circular RNA controls excitatory neurotransmission and restricts sensitivity to aversive stimuli.
2024 Scientific Article in Environmental Research Environ. Res. 252:118847 (2024)
Metabolomics in human SGBS cells as new approach method for studying adipogenic effects: Analysis of the effects of DINCH and MINCH on central carbon metabolism.
2024 Scientific Article in Nature metabolism Nat. Metab., DOI: 10.1038/s42255-024-01033-8 (2024)
Cold-induced expression of a truncated adenylyl cyclase 3 acts as rheostat to brown fat function.
2024 Editorial in Journal of Physiology - London J. Physiol.-London, DOI: 10.1113/JP286232 (2024)
Functions require junctions: Endurance exercise protects from age-induced alterations of the neuromuscular system.
2024 Position paper in Diabetologie, Die Diabetologie, DOI: 10.1007/s11428-024-01190-0 (2024)
Gestational diabetes mellitus (GDM), diagnosis, treatment, and follow-up: Abstract of the S3 guideline (AWMF registry number: 057-008).
2024 Scientific Article in Kidney & Blood Pressure Research Kidney Blood Press. Res. 49, 124-134 (2024)
SGLT2 inhibitors decrease overhydration and proteasuria in patients with chronic kidney disease: A longitudinal observational study.
2024 Review in Peptides Peptides 176:171198 (2024)
Regulation of energy metabolism through central GIPR signaling.
2024 Scientific Article in JTCVS Open JTCVS Open 18, 1-8 (2024)
Endovascular occlusion of segmental arteries feeding the anterior spinal artery to stage endovascular thoracoabdominal aortic repair.
2024 Letter to the Editor in Deutsche Medizinische Wochenschrift - DMW Dtsch. Med. Wochenschr. 149, 415-416 (2024)
Kommentar zu Adipositas/Typ-2-Diabetes: GLP-1 Agonist Tirzepatid fördert Gewichtsabnahme.
2024 Letter to the Editor in Diabetologie, Die Diabetologie 20, 309-311 (2024)
Adipositas.
2024 Scientific Article in JACC: Cardiovascular Interventions JACC-Cardiovasc. Interv. 17, 1134-1144 (2024)
Randomized trial comparing a stent-avoiding with a stent-preferred strategy in complex femoropopliteal lesions.
2024 Scientific Article in EClinicalMedicine EClinicalMedicine 72:102633 (2024)
Effect of timed dosing of usual antihypertensives according to patient chronotype on cardiovascular outcomes: The Chronotype sub-study cohort of the Treatment in Morning versus Evening (TIME) study.
2024 Position paper in Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet. 132, 68-82 (2024)
Recommendations for the nutritional prevention of type 2 diabetes mellitus.
2024 Position paper in Diabetologie, Die Diabetologie 20, 373–378 (2024)
Diabetes und Fettleber.
2024 Scientific Article in Hepatology Hepatology 81, 198-211 (2024)
Novel proteomic signatures may indicate MRI-assessed intrahepatic fat state and changes; the DIRECT PLUS clinical trial.
2024 Scientific Article in Cell Reports Cell Rep. 43:114008 (2024)
Stem cell-derived vessels-on-chip for cardiovascular disease modeling.
2024 Scientific Article in Nature metabolism Nat. Metab. 6, 1024-1035 (2024)
Inhibition of mammalian mtDNA transcription acts paradoxically to reverse diet-induced hepatosteatosis and obesity.
2024 Scientific Article in Breast Cancer Research Breast Cancer Res. 26:74 (2024)
TRPS1 maintains luminal progenitors in the mammary gland by repressing SRF/MRTF activity.
2024 Scientific Article in American Journal of Physiology - Renal Physiology Am. J. Physiol.-Renal Physiol. 326, F792-F801 (2024)
The calcium-sensing receptor has only a parathyroid hormone-dependent role in the acute response of renal phosphatetransporters to phosphate intake.
2024 Scientific Article in Acta Neuropathologica Acta Neuropathol. 147:64 (2024)
Microglial phagolysosome dysfunction and altered neural communication amplify phenotypic severity in Prader-Willi Syndrome with larger deletion.
2024 Scientific Article in Diabetes, Obesity and Metabolism Diabetes Obes. Metab. 26, 2054-2068 (2024)
The Obese Taste Bud study: Objectives and study design.
2024 Scientific Article in European Radiology Experimental Eur. Radiol. Exp. 8:37 (2024)
Diffusion tensor imaging in anisotropic tissues: Application of reduced gradient vector schemes in peripheral nerves.
2024 Review in Communications Medicine Commun. Med. 4:66 (2024)
Islet autoantibodies as precision diagnostic tools to characterize heterogeneity in type 1 diabetes: A systematic review.
2024 Scientific Article in Nature metabolism Nat. Metab., DOI: 10.1038/s42255-024-01025-8 (2024)
A spatiotemporal proteomic map of human adipogenesis.
2024 Scientific Article in JBMR Plus JBMR Plus 8:ziad016 (2024)
Pten knockout in mouse preosteoblasts leads to changes in bone turnover and strength.
2024 Review in Cardiovascular Diabetology Cardiovasc. Diabetol. 23:104 (2024)
CVOT Summit Report 2023: New cardiovascular, kidney, and metabolic outcomes.
2024 Scientific Article in Nature Communications Nat. Commun. 15:2475 (2024)
Context memory formed in medial prefrontal cortex during infancy enhances learning in adulthood.
2024 Scientific Article in Nutrition, Metabolism and Cardiovascular Diseases Nutr. Metab. Cardiovasc. Dis. 34, 1807-1816 (2024)
Circulatory levels of lysophosphatidylcholine species in obese adolescents: Findings from cross-sectional and prospective lipidomics analyses.
2024 Scientific Article in Human Brain Mapping Hum. Brain Mapp. 45:e26654 (2024)
White adipose tissue distribution and amount are associated with increased white matter connectivity.
2024 Review in Lancet Diabetes and Endocrinology Lancet Diabet. Endocrinol. 12, 277-284 (2024)
Tight versus liberal blood-glucose control in the intensive care unit: Special considerations for patients with diabetes.
2024 Review in Frontiers in Molecular Biosciences Front. Mol. Biosci. 11:1347397 (2024)
Transfer of membrane(s) matter(s)-non-genetic inheritance of (metabolic) phenotypes?
2024 Scientific Article in Neurobiology of Disease Neurobiol. Dis. 194:106474 (2024)
Engrailed 1 deficiency induces changes in ciliogenesis during human neuronal differentiation.
2024 Position paper in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 19, 331-333 (2024)
Entstehung und Prävention von Typ-1-Diabetes: die entscheidende Bedeutung der ersten Lebensjahre.
2024 Scientific Article in International Journal of Molecular Sciences Int. J. Mol. Sci. 25:2908 (2024)
Consequences of COVID-19 on adipose tissue signatures.
2024 Position paper in Diabetologie, Die Diabetologie 20, 312–319 (2024)
Pathophysiologie der Adipositas.
2024 Scientific Article in Environmental DNA Environ. DNA 6:e514 (2024)
Comparison of traditional and molecular surveys of fish biodiversity in southern Te Wāhipounamu/Fiordland (Aotearoa/New Zealand).
2024 Scientific Article in Advanced Optical Materials Adv. Opt. Mater. 2024:2303318 (2024)
Enhanced renal carcinomat treatment via synergistic photothermal/photodynamic therapy using hittorf's phosphorus-decorated polymeric carbon nitride heterostructure.
2024 Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet. 132, e1-e1 (2024)
Correction: Definition, Classification, Diagnosis and Differential Diagnosis of Diabetes Mellitus: Update 2023.
2024 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 109, 2571-2578 (2024)
Effect of breastfeeding duration on coagulation in women with and without history of gestational diabetes mellitus.
2024 Scientific Article in Molecular Metabolism Mol. Metab. 83:101915 (2024)
Loss of GIPR in LEPR cells impairs glucose control by GIP and GIP:GLP-1 co-agonism without affecting body weight and food intake in mice.
2024 Scientific Article in Science Advances Sci. Adv. 10:eadl1122 (2024)
Coxsackievirus infection induces direct pancreatic β cell killing but poor antiviral CD8+ T cell responses.
2024 Molecular Metabolism Mol. Metab. 82:101910 (2024)
Corrigendum to "Lack of Gαi2 proteins in adipocytes attenuates diet-induced obesity" [Mol Metab 40 (2020 Oct) 101029].
2024 Editorial in Biological Psychiatry Global Open Science Biol. Psychiatry Glob. Open. Sci. 4:100292 (2024)
Making sense of sex in neuroscience.
2024 Scientific Article in Sleep Sleep 47:zsae061 (2024)
Sleep slow oscillation-spindle coupling precedes spindle-ripple coupling during development.
2024 Position paper in Diabetologie, Die Diabetologie 20, 184–191 (2024)
Wechselwirkung zwischen eingeschränkter Insulinsekretionskapazität und Insulinresistenz.
2024 Review in Molecular Oncology Mol. Oncol., DOI: 10.1002/1878-0261.13590 (2024)
Cancer cachexia: Biomarkers and the influence of age.
2024 Editorial in Frontiers in Endocrinology Front. Endocrin. 15:1379994 (2024)
Editorial: Organ crosstalk in the pathophysiology and treatment of type-2 diabetes.
2024 Scientific Article in European Journal of Nutrition Eur. J. Nutr., DOI: 10.1007/s00394-024-03346-6 (2024)
Intake of B vitamins and the risk of developing islet autoimmunity and type 1 diabetes in the TEDDY study.
2024 Scientific Article in EBioMedicine EBioMedicine 101:105024 (2024)
Association between pre-diagnostic circulating lipid metabolites and colorectal cancer risk: A nested case-control study in the European Prospective Investigation into Cancer and Nutrition (EPIC).
2024 Scientific Article in Nature metabolism Nat. Metab. 6, 448-457 (2024)
Global, neuronal or β cell-specific deletion of inceptor improves glucose homeostasis in male mice with diet-induced obesity.
2024 Review in Journal of Physiology - London J. Physiol.-London 602, 1655-1658 (2024)
Turning fat into muscle: can this be an alternative to anti-obesity drugs such as semaglutide?
2024 Scientific Article in Diabetologia Diabetologia 67, 928-939 (2024)
Glucose tolerance and insulin resistance/sensitivity associate with retinal layer characteristics: The LIFE-Adult-Study.
2024 Scientific Article in Molecular Metabolism Mol. Metab. 82:101905 (2024)
Role of human Kallistatin in glucose and energy homeostasis in mice.
2024 Scientific Article in Diabetes/Metabolism Research and Reviews Diabetes Metab. Res. Rev. 40:e3777 (2024)
Clinical care advice for monitoring of islet autoantibody positive individuals with presymptomatic type 1 diabetes.
2024 Scientific Article in Proceedings of the National Academy of Sciences of the United States of America Proc. Natl. Acad. Sci. U.S.A. 121, 9:e2314423121 (2024)
Sleep shapes the associative structure underlying pattern completion in multielement event memory.
2024 Review in Frontiers in Nutrition Front. Nutr. 11:1322509 (2024)
Ketogenic diet and behavior: Insights from experimental studies.
2024 Scientific Article in Nature Methods Nat. Methods, DOI: 10.1038/s41592-024-02172-2 (2024)
Generation of complex bone marrow organoids from human induced pluripotent stem cells.
2024 Scientific Article in Pflügers Archiv Pflugers Arch. 476, 833-845 (2024)
A novel mouse model for familial hypocalciuric hypercalcemia (FHH1) reveals PTH-dependent and independent CaSR defects.
2024 Scientific Article in Journal of Perinatal Medicine J. Perinat. Med., DOI: 10.1515/jpm-2023-0413 (2024)
Correlation of fetal heart rate dynamics to inflammatory markers and brain-derived neurotrophic factor during pregnancy.
2024 Diabetologia Diabetologia 67, 758-758 (2024)
Correction to: Dose-response effects on HbA1c and bodyweight reduction of survodutide, a dual glucagon/GLP-1 receptor agonist, compared with placebo and open-label semaglutide in people with type 2 diabetes: A randomised clinical trial.
2024 Scientific Article in Nature Communications Nat. Commun. 15:1391 (2024)
Adipocyte p53 coordinates the response to intermittent fasting by regulating adipose tissue immune cell landscape.
2024 Review in FEBS Letters FEBS Lett., DOI: 10.1002/1873-3468.14818 (2024)
Lipid sensing nuclear receptors involved in the pathogenesis of fatty liver disease.
2024 Review in Physiology Physiology 39, 142-156 (2024)
Pharmacological advances in incretin-based polyagonism - what we know and what we don'tt.
2024 Scientific Reports Sci. Rep. 14:3841 (2024)
Author Correction: Blood and adipose tissue steroid metabolomics and mRNA expression of steroidogenic enzymes in periparturient dairy cows differing in body condition.
2024 Review in Diabetologie, Die Diabetologie 20, 176–183 (2024)
Epidemiologische und pathophysiologische Beziehungen zwischen Übergewicht, Adipositas und Typ-2-Diabetes.
2024 Review in Herz Herz 49, 118-123 (2024)
Cardiac proteostasis in obesity and cardiovascular disease.
2024 Position paper in Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet. 132, 136-141 (2024)
Diabetes and fatty liver.
2024 Position paper in Diabetologie, Die Diabetologie 20, 271–276 (2024)
Lipidtherapie bei Patienten mit Diabetes mellitus.Eine gemeinsame Stellungnahme der Kommission Fettstoffwechsel sowie der AG Herz und Diabetes der Deutschen Diabetes Gesellschaft (DDG), der Sektion Diabetes, Adipositas und Stoffwechsel der Deutschen Gesellschaft für Endokrinologie (DGE), der AG Herz und Diabetes der Deutschen Gesellschaft für Kardiologie (DGK) und der gemeinsamen AG Herz – Hormone – Diabetes der DGK, DGE und DDG.
2024 Scientific Article in Cell Research Cell Res. 34, 245-257 (2024)
MFSD7c functions as a transporter of choline at the blood-brain barrier.
2024 Scientific Article in Diabetes & vascular disease research Diab. Vasc. Dis. Res. 21:14791641231223701 (2024)
Utility of bioelectrical phase angle for cardiovascular risk assessment among individuals with and without diabetes mellitus.
2024 Position paper in Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet. 132, 64-67 (2024)
Diabetes Mellitus and the Heart.
2024 Scientific Article in Sleep Sleep 47:zsae015 (2024)
A patient-enriched MEIS1 coding variant causes a restless legs syndrome-like phenotype in mice.
2024 Position paper in Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet. 132, 68-82 (2024)
Nutritional recommendations for the prevention of type 2 diabetes mellitus.
2024 Position paper in Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet. 132, 112-124 (2024)
Definition, classification, diagnosis, and differential diagnosis of diabetes mellitus: Update 2023.
2024 Position paper in Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet. 132, 57-62 (2024)
Position paper on lipid therapy in patients with diabetes mellitus.
2024 Scientific Article in International Journal of Biological Macromolecules Int. J. Biol. Macromol. 265:130962 (2024)
Metabolic effects of SGLT2i and metformin on 3-hydroxybutyric acid and lactate in db/db mice.
2024 Scientific Article in BMJ Open Diabetes Research & Care BMJ Open Diab. Res. Care 12:e003865 (2024)
Omentin associates with serum metabolite profiles indicating lower diabetes risk: KORA F4 Study.
2024 Scientific Article in Biomarker Research Biomark. Res. 12:31 (2024)
Serum metabolite signatures of cardiac function and morphology in individuals from a population-based cohort.
2024 Scientific Article in Nature Cell Biology Nat. Cell Biol. 26, 113–123 (2024)
EPAC1 enhances brown fat growth and beige adipogenesis.
2024 Scientific Article in European Journal of Radiology Eur. J. Radiol. 172:111359 (2024)
Comparison of the accuracy of commercial two-point and multi-echo Dixon MRI for quantification of fat in liver, paravertebral muscles, and vertebral bone marrow.
2024 Review in Turkish Journal of Nephrology Turk. J. Nephrol. 33, 27-32 (2024)
Pleuroperitoneal leakage – Is this the end of peritoneal dialysis?
2024 Scientific Article in Nature Communications Nat. Commun. 15:1229 (2024)
T-bet+ B cells are activated by and control endogenous retroviruses through TLR-dependent mechanisms.
2024 Scientific Article in Magnetic Resonance in Medicine Magn. Reson. Med., DOI: 10.1002/mrm.30027 (2024)
Frequency shifts of free water signals from compact bone: Simulations and measurements using a UTE-FID sequence.
2024 Scientific Article in Thorax Thorax 79, 524-537 (2024)
COPD basal cells are primed towards secretory to multiciliated cell imbalance driving increased resilience to environmental stressors.
2024 Scientific Article in Cardiovascular Diabetology Cardiovasc. Diabetol. 23:44 (2024)
Independent association of thigh muscle fat density with vascular events in Korean adults.
2024 Position paper in Diabetologie, Die Diabetologie 20, 277–281 (2024)
Diabetes mellitus und Herz.
2024 Editorial in Metabolites Metabolites 14:8 (2024)
State-of-the-art metabolomics and lipidomics in life sciences: Methods and applications.
2024 Scientific Article in Nature Communications Nat. Commun. 15:586 (2024)
X-chromosome and kidney function: evidence from a multi-trait genetic analysis of 908,697 individuals reveals sex-specific and sex-differential findings in genes regulated by androgen response elements.
2024 Scientific Article in Diabetes Diabetes 73, 565-571 (2024)
Improved specificity of glutamate decarboxylase 65 autoantibody measurement using luciferase-based immunoprecipitation system (LIPS) assays.
2024 Scientific Article in Respiratory Research Respir. Res. 25:49 (2024)
Assessment of wood smoke induced pulmonary toxicity in normal- and chronic bronchitis-like bronchial and alveolar lung mucosa models at air-liquid interface.
2024 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab., DOI: 10.1210/clinem/dgad737 (2024)
Phase angle of bioelectrical impedance analysis as an indicator for diabetic polyneuropathy in type 2 diabetes mellitus.
2024 Scientific Article in European Radiology Experimental Eur. Radiol. Exp. 8:6 (2024)
Magnetization transfer ratio of the sciatic nerve differs between patients in type 1 and type 2 diabetes.
2024 Scientific Article in BMJ Paediatrics Open BMJ Paediatr. Open 8:e002212 (2024)
Vitamin D insufficiency in infants with increased risk of developing type 1 diabetes: A secondary analysis of the POInT Study.
2024 Scientific Article in Diabetologia Diabetologia 67, 670-678 (2024)
Early-childhood body mass index and its association with the COVID-19 pandemic, containment measures and islet autoimmunity in children with increased risk for type 1 diabetes.
2024 Scientific Article in European Respiratory Journal Eur. Respir. J. 63:2301326 (2024)
Sfrp1 inhibits lung fibroblast invasion during transition to injury induced myofibroblasts.
2024 Scientific Article in American Journal of Clinical Nutrition Am. J. Clin. Nutr. 119, 314-323 (2024)
Mixed nut consumption improves brain insulin sensitivity: A randomized, single-blinded, controlled, crossover trial in older adults with overweight or obesity.
2024 Scientific Article in Cardiovascular Research Cardiovasc. Res. 120, 385-402 (2024)
Cyclophilin A is a ligand for RAGE in thrombo-inflammation.
2024 Review in Hormone and Metabolic Research Horm. Metab. Res. 56, 51-64 (2024)
Animal and cell culture models of PPGLs - Achievements and limitations.
2024 Scientific Article in Biochemical Journal / Reviews Biochem. J. 481, 33-44 (2024)
Non-cross-linking advanced glycation end products affect prohormone processing.
2024 Scientific Article in European Journal of Clinical Nutrition Eur. J. Clin. Nutr., DOI: 10.1038/s41430-023-01393-6 (2024)
Detecting potential outliers in longitudinal data with time-dependent covariates.
2024 Scientific Article in Diabetes Care Diabetes Care 47, 362-370 (2024)
Outcomes with finerenone in patients with chronic kidney disease and type 2 diabetes by baseline insulin resistance.
2024 Scientific Article in Science Advances Sci. Adv. 10:eadi2689 (2024)
Transcriptional determinants of lipid mobilization in human adipocytes.
2024 Scientific Article in Cell and Tissue Research Cell Tissue Res. 395, 271–283 (2024)
Yap/Taz activity is associated with increased expression of phosphoglycerate dehydrogenase that supports myoblast proliferation.
2024 Scientific Article in Physiological reports Physiol. Rep. 12:e15901 (2024)
LncRNA U90926 is dispensable for the development of obesity-associated phenotypes in vivo.
2024 Scientific Article in Molecular Metabolism Mol. Metab. 79:101853 (2024)
Insulin regulates human pancreatic endocrine cell differentiation in vitro.
2024 Scientific Article in Adipocyte Adipocyte 13:2290218 (2024)
Inhibition of AHCY impedes proliferation and differentiation of mouse and human adipocyte progenitor cells.
2024 Scientific Article in Diabetologia Diabetologia 67, 275-289 (2024)
A diminished sciatic nerve structural integrity is associated with distinct peripheral sensory phenotypes in individuals with type 2 diabetes.
2024 Scientific Article in Obesity Obesity 32, 363-375 (2024)
Novel markers and networks related to restored skeletal muscle transcriptome after bariatric surgery.
2024 Scientific Article in Diabetes, Obesity and Metabolism Diabetes Obes. Metab. 26, 191-200 (2024)
Efficacy of finerenone in patients with type 2 diabetes, chronic kidney disease and altered markers of liver steatosis and fibrosis: A FIDELITY subgroup analysis.
2024 Review in Diabetes, Obesity and Metabolism Diabetes Obes. Metab. 26, 16-31 (2024)
Pancreatic islet cell plasticity: Pathogenic or therapeutically exploitable?
2023 Editorial in Nature Reviews Bioengineering Nat. Rev. Bioeng. 1, 154-155 (2023)
An engineering makeover of biomedical research.
2023 Scientific Article in Wellcome open research Wellcome Open Res. 8:483 (2023)
Large-scale exome array summary statistics resources for glycemic traits to aid effector gene prioritization.
2023 Alzheimer's & Dementia Poster: Basic Science and Pathogenesis – Part 1 (2023)
Individual bioenergetic capacity as a potential source of resilience to Alzheimer's disease.
2023 Scientific Article in Communications Medicine Commun. Med. 3:137 (2023)
Participant characteristics in the prevention of gestational diabetes as evidence for precision medicine: A systematic review and meta-analysis.
München, Technische Universität München, Fakultät für Medizin, Diss., 2023, 157 S.
The Role of Adipocyte-derived Extracellular Vesicles in Metabolic Diseases.
2023 Scientific Article in Frontiers in Genetics Front. Genet. 14:1323052 (2023)
High-resolution genomic profiling and locus-specific FISH in subcutaneous and visceral adipose tissue of obese patients.
2023 Review in Communications Medicine Commun. Med. 3:134 (2023)
Genotype-stratified treatment for monogenic insulin resistance: A systematic review.
2023 Scientific Article in Communications Medicine Commun. Med. 3:135 (2023)
Precision gestational diabetes treatment: A systematic review and meta-analyses.
2023 Review in Communications Medicine Commun. Med. 3:130 (2023)
Disease-modifying therapies and features linked to treatment response in type 1 diabetes prevention: A systematic review.
2023 Review in Communications Medicine Commun. Med. 3:131 (2023)
Treatment effect heterogeneity following type 2 diabetes treatment with GLP1-receptor agonists and SGLT2-inhibitors: A systematic review.
2023 Review in Communications Medicine Commun. Med. 3:136 (2023)
The use of precision diagnostics for monogenic diabetes: A systematic review and expert opinion.
2023 Review in Communications Medicine Commun. Med. 3:132 (2023)
Utility and precision evidence of technology in the treatment of type 1 diabetes: a systematic review.
2023 Review in Communications Medicine Commun. Med. 3:133 (2023)
Impact of individual and environmental factors on dietary or lifestyle interventions to prevent type 2 diabetes development: A systematic review.
2023 Scientific Article in Communications Medicine Commun. Med. 3:185 (2023)
Refining the diagnosis of gestational diabetes mellitus: A systematic review and meta-analysis.
2023 Scientific Article in Neuroscience Applied Neurosci. App. 2:101126 (2023)
GPR101 loss promotes insulin resistance and diet-induced obesity risk.
2023 Meeting abstract in Blood Blood 142:2708 (2023)
Human Induced Pluripotent Stem Cell-Derived Bone Marrow Organoids to Model Hematopoietic Development.
2023 Scientific Article in The Lancet Public Health Lancet Public Health 8, e453-e462 (2023)
Multiple morbidity across the lifespan in people with Down syndrome or intellectual disabilities: A population-based cohort study using electronic health records.
2023 Scientific Article in Padiatrische Praxis Padiat. Praxis 100, 86-96 (2023)
Genetic predisposition and environmental factors in the pathogenesis of type 1 diabetes.
2023 Editorial in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 18, 443-444 (2023)
Kommentar zu: T1D: Früherkennung, Schulung und Kontrolle senken Krankheitslast im Stadium 3.
2023 Scientific Article in Genes Genes 15:26 (2023)
Tribbles genes in gastric cancer: A tumor-suppressive role for TRIB2.
2023 Scientific Article in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 18, S330-S336 (2023)
Lipid therapy in patients with diabetes mellitus - A joint statement from the Fat Metabolism Commission and the Heart and Diabetes Working Group of the German Diabetes Society (DDG), the Diabetes, Obesity and Metabolism Section of the German Society for Endocrinology (DGE), the German Heart and Diabetes Working Group Society for Cardiology (DGK) and the joint working group Heart - Hormones - Diabetes of the DGK, DGE and DDG.
2023 Scientific Article in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 18, S324-S329 (2023)
Diabetes and fatty liver.
2023 Editorial in Nature metabolism Nat. Metab. 5, 1459-1460 (2023)
An integrated single-cell islet atlas in health and disease.
2023 Scientific Article in Metabolites Metabolites 13:12 (2023)
Single point insulin sensitivity estimator (SPISE) as a prognostic marker for emerging dysglycemia in children with overweight or obesity.
2023 Scientific Article in Human Mutation Hum. Mutat. 2023:17 (2023)
A likelihood ratio approach for utilizing case-control data in the clinical classification of rare sequence variants: Application to BRCA1 and BRCA2.
2023 Scientific Article in Molecular Psychiatry Mol. Psychiatry, DOI: 10.1038/s41380-023-02331-5 (2023)
Maternal educational attainment in pregnancy and epigenome-wide DNA methylation changes in the offspring from birth until adolescence.
2023 Review in Journal of Clinical Investigation J. Clin. Invest. 133:11 (2023)
Increased cell senescence in human metabolic disorders.
2023 Scientific Article in BMC Medicine BMC Med. 21:504 (2023)
The citrate transporter SLC13A5 as a therapeutic target for kidney disease: Evidence from Mendelian randomization to inform drug development.
2023 Scientific Article in Metabolites Metabolites 13:1186 (2023)
Targeting longevity gene SLC13A5: A novel approach to prevent age-related bone fragility and osteoporosis.
2023 Review in Frontiers in Molecular Biosciences Front. Mol. Biosci. 10:1336416 (2023)
Neither too much nor too little: Mitochondrial calcium concentration as a balance between physiological and pathological conditions.
2023 Scientific Article in Lancet Diabetes and Endocrinology Lancet Diabet. Endocrinol. 12, 119-131 (2023)
Analysis of type 2 diabetes heterogeneity with a tree-like representation: Insights from the prospective German Diabetes Study and the LURIC cohort.
2023 Scientific Article in Molecular Metabolism Mol. Metab. 80:101868 (2023)
Endothelin receptor B-deficient mice are protected from high-fat diet-induced metabolic syndrome.
2023 Masterclass in Neuroendocrinology Mast. Neuroend. 11, C1-C2 (2023)
Correction to: Control of Systemic Metabolism by Astrocytes in the Brain (Springer Nature, 10.1007/978-3-030-62383-8_6).
2023 Scientific Article in Kidney International Kidney Int. 105, 844-864 (2023)
Implication of transcription factor FOXD2 dysfunction in syndromic congenital anomalies of the kidney and urinary tract (CAKUT).
2023 Scientific Article in Diabetologia Diabetologia, 13 (2023)
Dose-response effects on HbA1c and bodyweight reduction of survodutide, a dual glucagon/GLP-1 receptor agonist, compared with placebo and open-label semaglutide in people with type 2 diabetes: A randomised clinical trial.
2023 Scientific Article in International Journal of Molecular Sciences Int. J. Mol. Sci. 24:16850 (2023)
The role of phosphatidylethanolamine N-methyltransferase (PEMT) and its waist-hip-ratio-associated locus rs4646404 in obesity-related metabolic Traits and liver disease.
2023 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 109, 1318-1327 (2023)
Skeletal muscle gene expression signatures of obese high- and low- responders to endurance exercise training.
2023 Review in Current Opinion in Nephrology & Hypertension Curr. Opin. Nephrol. Hypertens. 33, 220-225 (2023)
Eryptosis: A driver of anemia in chronic kidney disease.
2023 Review in Science Translational Medicine Sci. Transl. Med. 15:eadh4453 (2023)
Seeking satiety: From signals to solutions.
2023 Scientific Article in Adipocyte Adipocyte 14:2283213 (2023)
Adipogenic characterization of immortalized CD55+ progenitor cells from human white adipose tissue.
2023 Scientific Article in Nature Communications Nat. Commun. 14:8175 (2023)
Astrocytic insulin receptor controls circadian behavior via dopamine signaling in a sexually dimorphic manner.
2023 Scientific Article in Frontiers in Endocrinology Front. Endocrin. 14:1243910 (2023)
Long-term green-Mediterranean diet may favor fasting morning cortisol stress hormone; the DIRECT-PLUS clinical trial.
In: Handbook of Obesity - Volume 1: Epidemiology, Etiology, and Physiopathology, Fourth Edition. 2023. 496-502 ( ; 1)
Obesity and Type 2 Diabetes.
2023 Review in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 18, S449-S465 (2023)
Empfehlungen zur Ernährungsprävention des Typ-2-Diabetes mellitus.
2023 Scientific Article in Nature biomedical engineering Nat. Bio. Eng. 7, 1667-1682 (2023)
Dermal features derived from optoacoustic tomograms via machine learning correlate microangiopathy phenotypes with diabetes stage.
2023 Review in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 18, S337-S341 (2023)
Diabetes mellitus und Herz.
2023 Scientific Article in Nature metabolism Nat. Metab. 5, 2075–2085 (2023)
Glucose-dependent insulinotropic polypeptide regulates body weight and food intake via GABAergic neurons in mice.
2023 Scientific Article in Frontiers in Endocrinology Front. Endocrin. 14:1249863 (2023)
E47 as a novel glucocorticoid-dependent gene mediating lipid metabolism in patients with endogenous glucocorticoid excess.
2023 Scientific Article in Food Quality and Preference Food. Qual. Prefer. 112:105035 (2023)
The German Leeds food preference Questionnaire (LFPQ-G): A validation study.
2023 Review in Deutsches Ärzteblatt international Dtsch. Arztebl. Int. 120, 107-114 (2023)
Refeeding syndrome.
2023 Scientific Article in Proceedings of SPIE Proc. SPIE 12649, DOI: 10.1117/12.2681388 (2023)
Fatty tissue as a modulator of cancer cell mechanics.
2023 Review in Diabetologie, Die Diabetologie 19, 698-701 (2023)
Diabetes mellitus und Herz.
2023 Scientific Article in Diabetologie, Die Diabetologie 19, 459-463 (2023)
Diabetes und Fettleber.
2023 Scientific Article in Obesity Facts Obes. Facts 16, 447-456 (2023)
Patient-related predictors for seeking and receiving obesity surgery.
2023 Scientific Article in Reproductive Biology and Endocrinology Repr. Biol. Endocrin. 21:96 (2023)
Circulating acyl-CoA-binding protein/diazepam-binding inhibitor in gestational diabetes mellitus.
2023 Other: Opinion in Diabetologie, Die Diabetologie 19, 931–932 (2023)
Behandlung des Gestationsdiabetes in der Frühschwangerschaft.
2023 Editorial in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 18, 335-338 (2023)
Regulation des Energiestoffwechsel durch GIP und GIPR:GLP-1R Ko-Agonisten.
2023 Scientific Article in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 18, S228-S238 (2023)
Gestationsdiabetes mellitus (GDM), Diagnostik, Therapie und Nachsorge - Kurzfassung der S3-Leitlinie (AWMF-Registernummer: 057-008).
2023 Editorial in Nature Reviews - Gastroenterology & Hepatology Nat. Rev. Gastroenterol. Hepatol., DOI: 10.1038/s41575-023-00880-2 (2023)
Role of steatotic liver disease in prediction and prevention of cardiometabolic diseases.
2023 Editorial in Med (N Y) Med. 4, 849-851 (2023)
SURMOUNTing body weight barriers in type 2 diabetes.
2023 Scientific Article in Nature Communications Nat. Commun. 14:7674 (2023)
A reversible state of hypometabolism in a human cellular model of sporadic Parkinson's disease.
2023 Letter to the Editor in Diabetologie, Die Diabetologie 19, 444-449 (2023)
Lipidtherapie bei Patienten mit Diabetes mellitus.Eine gemeinsame Stellungnahme der Kommission Fettstoffwechsel sowie der AG Herz und Diabetes der Deutschen Diabetes Gesellschaft (DDG), der Sektion Diabetes, Adipositas und Stoffwechsel der Deutschen Gesellschaft für Endokrinologie (DGE), der AG Herz und Diabetes der Deutschen Gesellschaft für Kardiologie (DGK) und der gemeinsamen AG Herz – Hormone – Diabetes der DGK, DGE und DDG.
2023 Review in Internistische Praxis Internist. Prax. 66, 373-383 (2023)
Genetische Prädisposition und Umweltfaktoren in der Pathogenese des Typ-1-Diabetes.
2023 Scientific Article in Diabetes Aktuell Diabetes akt. 21, 166-170 (2023)
Typ-1-Diabetes: Screening, Prävention und neue Therapien.
2023 Scientific Article in Diabetes Care Diabetes Care 46, 1409-1416 (2023)
Physical activity and the development of islet autoimmunity and type 1 diabetes in 5-to 15-year-old children followed in the TEDDY study.
2023 Scientific Article in Diabetes Aktuell Diabetes akt. 21, 172-176 (2023)
Klinische Studien zur Prävention und Therapie von Diabetes.
2023 Editorial in Deutsche Medizinische Wochenschrift - DMW Dtsch. Med. Wochenschr. 148, 957-963 (2023)
Versorgungssituation für Menschen mit Adipositas in Deutschland.
2023 Scientific Article in Diabetologie, Die Diabetologie 19, 758-766 (2023)
Stillen als Präventionsmaßnahme bei fetaler Fehlprogrammierung.
2023 Review in Diabetologie, Die Diabetologie 19, 112-116 (2023)
Einfache Einteilung der Subtypen des Diabetes in der Praxis.Ein Kommentar.
2023 Review in Innere Medizin Innere Med. 64, 636-641 (2023)
Prädiabetes als therapeutische Herausforderung in der Inneren Medizin.
2023 Letter to the Editor in Clinical and Translational Discovery Clin. Transl. Discovery 3:e230 (2023)
Live lean and CRISPR – Engineering metabolism with FGF21 and FNDC5.
2023 Scientific Article in Journal of Endocrinology J. Endocrinol. 259:e230166 (2023)
Quercetin improves white adipose tissue redox homeostasis in ovariectomized rats.
2023 Scientific Article in BioSpektrum BioSpektrum 29, 137-139 (2023)
GLP-1-Mimetika – wegweisend zur Behandlung von Diabetes und Adipositas.
In: Encyclopedia of Human Nutrition: Volume 1-4, Fourth Edition. 2023. 161-167 ( ; 1-4)
Microbiota of the intestine: Biology and physiological functions.
2023 Scientific Article in Collabra: Psychology Collabra: Psychology 9:71316 (2023)
Unfamiliar contexts compared to familiar contexts impair learning in humans.
2023 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab., DOI: 10.1210/clinem/dgad550 (2023)
Circulating miRNAs detect high versus low visceral adipose tissue inflammation in patients living with obesity.
2023 Scientific Article in Gut Microbes Gut Microbes 15:2264457 (2023)
Successful weight regain attenuation by autologous fecal microbiota transplantation is associated with non-core gut microbiota changes during weight loss; randomized controlled trial.
2023 Review in Current Obesity Reports Curr. Obes. Rep. 12, 482-501 (2023)
Genetics and epigenetics in obesity: What do we know so far?
2023 Scientific Article in Biomedicines Biomedicines 11:11 (2023)
Laminin α4 expression in human adipose tissue depots and its association with obesity and obesity related traits.
2023 Scientific Article in Nature Communications Nat. Commun. 14:6742 (2023)
Maternal thyroid hormone receptor β activation in mice sparks brown fat thermogenesis in the offspring.
2023 Scientific Article in ChemBioChem ChemBioChem:e202300550 (2023)
Immunological quantitation of the glycation site lysine-414 in serum albumin in human plasma samples by indirect ELISA using highly specific monoclonal antibodies.
2023 Scientific Article in Molecular Medicine Mol. Med. 29:138 (2023)
Knockout of STE20-type kinase TAOK3 does not attenuate diet-induced NAFLD development in mice.
2023 Scientific Article in FEBS Journal, The FEBS J., DOI: 10.1111/febs.16991 (2023)
LRP1 is the cell-surface endocytosis receptor for vaspin in adipocytes.
2023 Scientific Article in Frontiers in Nutrition Front. Nutr. 10:1275160 (2023)
Differential expression of immunoregulatory cytokines in adipose tissue and liver in response to high fat and high sugar diets in female mice.
2023 Scientific Article in Diabetes Care Diabetes Care 46, 2067-2075 (2023)
Epigenome-wide meta-analysis reveals associations between dietary glycemic index and glycemic load and DNA methylation in children and adolescents of different body sizes.
2023 Scientific Article in Diabetes Diabetes 73, 135-146 (2023)
Sensory phenotypes provide insight into the natural course of diabetic polyneuropathy.
2023 Editorial in Frontiers in Oncology Front. Oncol. 13:1305140 (2023)
Editorial: Translational research for better diagnosis and treatment of endometrial cancer.
2023 Scientific Article in Endocrine-Related Cancer Endocr. Relat. Cancer 30:12 (2023)
Regulation of epinephrine biosynthesis in HRAS-mutant paragangliomas.
2023 Scientific Article in European Journal of Endocrinology Eur. J. Endocrinol. 189, 546-565 (2023)
Responses to systemic therapy in metastatic pheochromocytoma/paraganglioma: A retrospective multicenter cohort study.
2023 Scientific Article in Diabetologie, Die Diabetologie 19, 56-66 (2023)
Gestational diabetes mellitus (GDM), diagnostics, therapy and aftercare Practice Recommendation-Abstract of the S3 Guideline (AWMF Register Number: 057-008).
2023 Scientific Article in Diabetologie, Die Diabetologie 19, 44-55 (2023)
Definition, classification and diagnosis of diabetes mellitus: Update 2022.
2023 Scientific Article in Diabetes Care Diabetes Care 46, 1753-1761 (2023)
Refining the definition of stage 1itype 1 diabetes: An ontology-driven analysis of the heterogeneity of multiple Islet autoimmunity.
2023 Scientific Article in Cancer Medicine Cancer Med. 12, 16142-16162 (2023)
Association of the CHEK2 c.1100delC variant, radiotherapy, and systemic treatment with contralateral breast cancer risk and breast cancer-specific survival.
2023 Scientific Article in American Journal of Clinical Nutrition Am. J. Clin. Nutr. 118, 1099-1105 (2023)
Associations of dietary patterns between age 9 and 24 months with risk of celiac disease autoimmunity and celiac disease among children at increased risk.
2023 Scientific Article in Wiener klinische Wochenschrift Wien. Klin. Wochenschr. 135, 325-335 (2023)
Common procedures and conditions leading to inpatient hospital admissions in adults with and without diabetes from 2015 to 2019 in Germany: A comparison of frequency, length of hospital stay and complications.
2023 Editorial in Diabetologie, Die Diabetologie 19, 103-105 (2023)
Mit präzisen Ansätzen die "patient journey" optimieren. Neue Wege der gezielteren Diabetesprävention und -therapie.
2023 Scientific Article in American Journal of Physiology - Cell Physiology Am. J. Physiol.-Cell Physiol. 325, C1131-C1143 (2023)
Redox state and altered pyruvate metabolism contribute to a dose-dependent metformin-induced lactate production of human myotubes.
2023 Scientific Article in Communications Medicine Commun. Med. 3:138 (2023)
Precision subclassification of type 2 diabetes: A systematic review.
2023 Scientific Article in Deutsche Medizinische Wochenschrift - DMW Dtsch. Med. Wochenschr. 148, 1225-1226 (2023)
60-jähriger Mann mit unklarer Proteinurie und auffälligen Strukturen in der Niere.
2023 Scientific Article in Lancet Diabetes and Endocrinology Lancet Diabet. Endocrinol. 11, 798-810 (2023)
Mechanisms of weight loss-induced remission in people with prediabetes: A post-hoc analysis of the randomised, controlled, multicentre Prediabetes Lifestyle Intervention Study (PLIS).
2023 Scientific Article in Diabetes Research and Clinical Practice Diabetes Res. Clin. Pract. 204:110908 (2023)
Rationale and design of a randomised phase III registration trial investigating finerenone in participants with type 1 diabetes and chronic kidney disease: The FINE-ONE trial.
2023 Scientific Article in Metabolites Metabolites 13:12 (2023)
A new biomarker profiling strategy for gut microbiome research: Valid association of metabolites to metabolism of microbiota detected by non-targeted metabolomics in human urine.
2023 Scientific Article in Reproductive Sciences Reprod. Sci., DOI: 10.1007/s43032-023-01384-9 (2023)
Exploring the influence of fetal sex on heart rate dynamics using fetal magnetocardiographic recordings.
2023 Editorial in Lancet Diabetes and Endocrinology Lancet Diabet. Endocrinol. 11, 883-884 (2023)
Glycaemic fluctuations across the menstrual cycle: Possible effect of the brain.
2023 Scientific Article in Ultraschall in der Medizin Ultraschall Med., DOI: 10.1055/a-2204-5814 (2023)
Endoscopic ultrasound-guided ethanol ablation versus surgical resection of insulinomas.
2023 Scientific Article in International Journal of Molecular Sciences Int. J. Mol. Sci. 24:13 (2023)
Identification of MicroRNAs associated with prediabetic status in obese women.
2023 Scientific Article in Transplantation Direct Transplant. Direct. 9:e1558 (2023)
Development and validation of a new score to assess the risk of posttransplantation diabetes mellitus in kidney transplant recipients.
2023 Editorial in Frontiers in cell and developmental biology Front. Cell Dev. Biol. 11:1287533 (2023)
Editorial: Healthy adipose tissue expansion.
2023 Scientific Article in European Journal of Pharmacology Eur. J. Pharmacol. 960:176158 (2023)
Insights into the mechanism of action of the chlorophyll derivative 13-2-hydroxypheophytine a on reducing neutral lipid reserves in zebrafish larvae and mice adipocytes.
2023 Scientific Article in Cell Reports Cell Rep. 42:113305 (2023)
High-calorie diets uncouple hypothalamic oxytocin neurons from a gut-to-brain satiation pathway via κ-opioid signaling.
2023 Scientific Article in Frontiers in cell and developmental biology Front. Cell Dev. Biol. 11:1240558 (2023)
A missense mutation in Ehd1 associated with defective spermatogenesis and male infertility.
2023 Scientific Article in Frontiers in Endocrinology Front. Endocrin. 14:1286590 (2023)
NEUROD2 function is dispensable for human pancreatic β cell specification.
2023 Scientific Article in Hemasphere Hemasphere 7:e958 (2023)
CSF3R T618I collaborates With RUNX1-RUNX1T1 to expand hematopoietic progenitors and sensitizes to GLI inhibition.
2023 Scientific Article in Microbiology resource announcements : MRA Microbio. Res. Ann. 12:e0022023 (2023)
Genome sequences of bla NDM-1 producing Acinetobacter lactucae isolated from immunocompromised patients in India.
2023 Scientific Article in Nature Nature 623, 772-781 (2023)
Single-cell, whole-embryo phenotyping of mammalian developmental disorders.
2023 Scientific Article in Frontiers in Endocrinology Front. Endocrin. 14:1223162 (2023)
Association of sex hormones and sex hormone-binding globulin with liver fat in men and women: An observational and Mendelian randomization study.
2023 Scientific Article in ACS Nano ACS Nano 17, 21056-21072 (2023)
Nanoparticle-exposure-triggered virus reactivation induces lung emphysema in mice.
2023 Scientific Article in Obesity Obesity 31, 2986-2997 (2023)
Visceral adipocyte size links obesity with dysmetabolism more than fibrosis, and both can be estimated by circulating miRNAs.
2023 Scientific Article in Obesity Surgery Obes. Surg. 33, 3391-3401 (2023)
Barrett`s esophagus in bariatric surgery: Regression or progression?
2023 Scientific Article in BMC Medicine BMC Med. 21:364 (2023)
The effect of polyphenols on DNA methylation-assessed biological age attenuation: The DIRECT PLUS randomized controlled trial.
2023 Scientific Article in Obesity Obesity 31, 2862-2874 (2023)
Genetic dissection of serum vaspin highlights its causal role in lipid metabolism.
2023 Scientific Article in Blood advances Blood Adv. 7, 5055-5068 (2023)
Activated protein C modulates T-cell metabolism and epigenetic FOXP3 induction via α-ketoglutarate.
2023 Scientific Article in Nutrients Nutrients 15:13 (2023)
Development, design and utilization of a CDSS for refeeding syndrome in real life inpatient care—a feasibility study.
2023 Scientific Article in Journal of the Endocrine Society J. Endocr. Soc. 7:bvad072 (2023)
Metreleptin robustly increases resting-state brain connectivity in treatment-naïve female patients with lipodystrophy.
2023 Scientific Article in Peptides Peptides 167:171047 (2023)
FAM3D: A gut secreted protein and its potential in the regulation of glucose metabolism.
2023 Editorial in Nature metabolism Nat. Metab. 5, 1642-1645 (2023)
Career pathways, part 12.
2023 Scientific Article in Obesity Surgery Obes. Surg. 33, 2375-2383 (2023)
Impact of surgical postponements due to Covid-19 on weight and metabolic parameters in bariatric surgery in Germany: Monocentric experiences and considerations in a national context.
2023 Letter to the Editor in The Lancet Regional Health - Europe Lancet Reg. Health-Eur. 33:100734 (2023)
Are there relevant thresholds of insulin-independent indices across the lifespan to predict alterations in glycemic control?—Authors’ reply.
2023 Scientific Article in EMBO Reports EMBO Rep. 24:e57600 (2023)
The obesity-linked human lncRNA AATBC stimulates mitochondrial function in adipocytes.
2023 Scientific Article in iScience iScience 26:107841 (2023)
Identifying G protein-coupled receptors involved in adipose tissue function using the innovative RNA-seq database FATTLAS.
2023 Review in Nature Reviews - Endocrinology Nat. Rev. Endocrinol. 19, 691-707 (2023)
The evolving functions of the vasculature in regulating adipose tissue biology in health and obesity.
2023 Scientific Article in Journal of Endovascular Therapy J. Endovascular Ther., DOI: 10.1177/15266028231202456 (2023)
Outcomes of percutaneous access to the first versus third segment of axillary artery during aortic procedures.
2023 Scientific Article in Nature Cancer Nat. Cancer 4, 1544-1560 (2023)
Endothelial Notch1 signaling in white adipose tissue promotes cancer cachexia.
2023 Editorial in Frontiers in Physiology Front. Physiol. 14:1275319 (2023)
Editorial: Metabolism in nonalcoholic fatty liver disease.
2023 Scientific Article in Molecular Therapy Mol. Ther. 31, 2408-2421 (2023)
Development of a peptide drug restoring AMPK and adipose tissue functionality in cancer cachexia.
2023 Editorial in Nature metabolism Nat. Metab. 5, 1080-1081 (2023)
Brown fat has a sweet tooth.
2023 Letter to the Editor in BioEssays Bioessays 45:e2300093 (2023)
Endocrine communication of endoplasmic reticulum stress.
2023 Scientific Article in Methods in Enzymology Methods Enzymol. 689, 201-234 (2023)
17β-Hydroxysteroid dehydrogenases types 1 and 2: Enzymatic assays based on radiometric and mass-spectrometric detection.
2023 Letter to the Editor in Diabetologia Diabetologia 66, 2389-2390 (2023)
Presymptomatic type 1 diabetes and disease severity at onset. Reply to Schneider J, Gemulla G, Kiess W et al [letter].
2023 Scientific Article in Light: Science & Applications Light Sci. Appl. 12:231 (2023)
Opening a window to skin biomarkers for diabetes stage with optoacoustic mesoscopy.
2023 Scientific Article in EClinicalMedicine EClinicalMedicine 64:102208 (2023)
Characterisation and clinical outcomes in children and adolescents with diabetes according to newly defined subgroups: A cohort study from the DPV registry.
2023 Scientific Article in Cell Reports Medicine Cell Rep. Med. 4:101093 (2023)
Plasma protein biomarkers predict the development of persistent autoantibodies and type 1 diabetes 6 months prior to the onset of autoimmunity.
2023 Scientific Article in Diabetologia Diabetologia 66, 1633-1642 (2023)
Children diagnosed with presymptomatic type 1 diabetes through public health screening have milder diabetes at clinical manifestation.
2023 Scientific Article in JAMA: Journal of the American Medical Association JAMA 330, 1151-1160 (2023)
SARS-CoV-2 infection and development of islet autoimmunity in early childhood.
2023 Scientific Article in Nature metabolism Nat. Metab. 5, 1475-1482 (2023)
Brain insulin action on peripheral insulin sensitivity in women depends on menstrual cycle phase.
2023 Review in Diabetes, Obesity and Metabolism Diabetes Obes. Metab. 25, 3444-3452 (2023)
The ‘Behavioral Balance Model’: A new perspective on the aetiology and therapy of obesity.
2023 Scientific Article in Journal of Nephrology J. Nephrol. 36, 2133-2138 (2023)
Standardized, risk-adapted induction therapy in kidney transplantation.
2023 Scientific Article in International Journal of Obesity Int. J. Obes. 47, 825-832 (2023)
Acylated- and unacylated ghrelin during an oral glucose tolerance test in humans at risk for type 2 diabetes mellitus.
2023 Scientific Article in Behavioural Brain Research Behav. Brain Res. 452:114545 (2023)
Rearing is critical for forming spatial representations in pre-weanling rats.
2023 Review in Nature medicine Nat. Med. 29, 2438-2457 (2023)
Second international consensus report on gaps and opportunities for the clinical translation of precision diabetes medicine.
2023 Scientific Article in Marine Drugs Mar. Drugs 21:498 (2023)
Metabolite profile characterization of cyanobacterial strains with bioactivity on lipid metabolism using in vivo and in vitro approaches.
2023 Editorial in Nature metabolism Nat. Metab. 5, 1454-1455 (2023)
Astrocytic GABA in LHA is an obesity ‘thermostat’.
2023 Scientific Article in Nature Cell Biology Nat. Cell Biol. 25, 975-988 (2023)
Class 3 PI3K coactivates the circadian clock to promote rhythmic de novo purine synthesis.
2023 Scientific Article in BMC Biology BMC Biol. 21:150 (2023)
Reduced intestinal lipid absorption improves glucose metabolism in aged G2-Terc knockout mice.
2023 Review in Biomolecules Biomolecules 13:41 (2023)
(Patho)physiology of glycosylphosphatidylinositol-anchored proteins II: Intercellular transfer of matter (Inheritance?) that matters.
2023 Scientific Article in Scientific Reports Sci. Rep. 13:9908 (2023)
Placebo effects on nausea and motion sickness are resistant to experimentally-induced stress.
2023 Scientific Article in Nature Protocols Nat. Protoc. 18, 2181-2220 (2023)
Ex vivo immunocapture and functional characterization of cell-type-specific mitochondria using MitoTag mice.
2023 Scientific Article in Stem Cell Reports Stem Cell Rep. 18, 1972-1986 (2023)
Single-cell characterization of neovascularization using hiPSC-derived endothelial cells in a 3D microenvironment.
2023 Review in Diabetologia Diabetologia 66, 1378-1394 (2023)
100 years of glucagon and 100 more.
2023 Scientific Article in Computers in Biology and Medicine Comput. Biol. Med. 163:107085 (2023)
Shared gene expression signatures between visceral adipose and skeletal muscle tissues are associated with cardiometabolic traits in children with obesity.
2023 Scientific Article in Frontiers in cell and developmental biology Front. Cell Dev. Biol. 11:1240039 (2023)
Inceptor facilitates acrosomal vesicle formation in spermatids and is required for male fertility.
2023 Scientific Article in Cell Metabolism Cell Metab. 35, 1736-1751.e7 (2023)
Regulatory T cells require IL6 receptor alpha signaling to control skeletal muscle function and regeneration.
2023 Scientific Article in Nature metabolism Nat. Metab. 5, 1615-1637 (2023)
Delineating mouse β-cell identity during lifetime and in diabetes with a single cell atlas.
2023 Scientific Article in BMJ Open Diabetes Research & Care BMJ Open Diab. Res. Care 11:e003422 (2023)
Circulating metabolites improve the prediction of renal impairment in patients with type 2 diabetes.
2023 Scientific Article in Human Molecular Genetics Hum. Mol. Genet. 32, 2717-2734 (2023)
Insights into energy balance dysregulation from a mouse model of methylmalonic aciduria.
2023 Review in Mammalian Genome Mamm. Genome 34, 107-122 (2023)
A review of standardized high-throughput cardiovascular phenotyping with a link to metabolism in mice.
2023 Letter to the Editor in European Journal of Epidemiology Eur. J. Epidemiol. 38, 713-715 (2023)
Lessons from the Singapore cohorts showcase symposium—open call for collaborations.
2023 Scientific Article in Cardiovascular Diabetology Cardiovasc. Diabetol. 22:141 (2023)
Identification of candidate metabolite biomarkers for metabolic syndrome and its five components in population-based human cohorts.
2023 Scientific Article in American Journal of Human Genetics, The Am. J. Hum. Genet. 110, 1068-1085 (2023)
Null and missense mutations of ERI1 cause a recessive phenotypic dichotomy in humans.
2023 Scientific Article in Molecular Metabolism Mol. Metab. 75:101768 (2023)
Maternal hyperglycemia induces alterations in hepatic amino acid, glucose and lipid metabolism of neonatal offspring: Multi-omics insights from a diabetic pig model.
2023 Science of the Total Environment, The Sci. Total Environ. 905:167050 (2023)
Corrigendum to “Longitudinal associations between metabolites and immediate, short- and medium-term exposure to ambient air pollution: Results from the KORA cohort study” [Sci. Total Environ. 900 (2023) 165780] (Science of the Total Environment (2023) 900, (S0048969723044030), (10.1016/j.scitotenv.2023.165780)).
2023 Scientific Article in Frontiers in Nutrition Front. Nutr. 10:1147407 (2023)
Associations between vitamin D, immunoglobulin E concentrations, and obesity.
2023 Review in Diabetes, Obesity and Metabolism Diabetes Obes. Metab. 25, 2058-2072 (2023)
New insights into the treatment of obesity.
2023 Scientific Article in EBioMedicine EBioMedicine 91:104569 (2023)
Metabolic role of the hepatic valine/3-hydroxyisobutyrate (3-HIB) pathway in fatty liver disease.
2023 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 108, e1074-e1081 (2023)
Serum scEMC10 levels are negatively associated with resting metabolic rate and age in humans.
2023 Scientific Article in Hepatology communications Hepat. Commun. 7:17 (2023)
Silencing of STE20-type kinase TAOK1 confers protection against hepatocellular lipotoxicity through metabolic rewiring.
2023 Scientific Article in Nature Communications Nat. Commun. 14:1438 (2023)
An integrated single cell and spatial transcriptomic map of human white adipose tissue.
2023 Scientific Article in Journal of Clinical Medicine J. Clin. Med. 12:11 (2023)
Feasibility and safety of percutaneous axillary artery access in a prospective series of 100 complex aortic and aortoiliac interventions.
2023 Scientific Article in Frontiers in Endocrinology Front. Endocrin. 14:1146454 (2023)
Overexpressing high levels of human vaspin limits high fat diet-induced obesity and enhances energy expenditure in a transgenic mouse.
2023 Scientific Article in International Journal of Molecular Sciences Int. J. Mol. Sci. 24:12 (2023)
Obesity is associated with distorted proteoglycan expression in adipose tissue.
2023 Scientific Article in Frontiers in Genetics Front. Genet. 14:1128133 (2023)
Genetic variants in genes involved in creatine biosynthesis in patients with severe obesity or anorexia nervosa.
2023 Scientific Article in Journal of the Endocrine Society J. Endocr. Soc. 7:bvad052 (2023)
Reward processing during monetary incentive delay task after leptin substitution in lipodystrophy-an fMRI case series.
2023 Scientific Article in Frontiers in Endocrinology Front. Endocrin. 14:1152444 (2023)
Renal function is a major predictor of circulating acyl-CoA-binding protein/diazepam-binding inhibitor.
2023 Review in Innere Medizin Innere Med. 64, 629-635 (2023)
Adipositastherapie – werden Pharmakotherapien die Alternative zur metabolischen Chirurgie sein?
2023 Scientific Article in Scientific Reports Sci. Rep. 13:9029 (2023)
Delta weight loss unlike genetic variation associates with hyperoxaluria after malabsorptive bariatric surgery.
2023 Review in Biomedicines Biomedicines 11:26 (2023)
Adipokines as clinically relevant therapeutic targets in obesity.
2023 Review in Biomedicines Biomedicines 11:25 (2023)
Adipokines in pregnancy: A systematic review of clinical data.
2023 Scientific Article in Metabolism: clinical and experimental Metabolism 145:155594 (2023)
A polyphenol-rich green Mediterranean diet enhances epigenetic regulatory potential: The DIRECT PLUS randomized controlled trial.
2023 Scientific Article in American Journal of Human Genetics, The Am. J. Hum. Genet. 110, 998-1007 (2023)
Monoallelic intragenic POU3F2 variants lead to neurodevelopmental delay and hyperphagic obesity, confirming the gene's candidacy in 6q16.1 deletions.
2023 Scientific Article in Frontiers in Cellular Neuroscience Front. Cell. Neurosci. 17:1165887 (2023)
Cultured brain pericytes adopt an immature phenotype and require endothelial cells for expression of canonical markers and ECM genes.
2023 Editorial in European Heart Journal Eur. Heart J. 44, 4281-4283 (2023)
Third generation PCSK9-Inhibitors.
2023 Scientific Article in Biomedicines Biomedicines 11:13 (2023)
Association between TGFβ1 levels in cord blood and weight progress in the first year of life.
2023 Review in Frontiers in Endocrinology Front. Endocrin. 14:1181002 (2023)
Implication of DNA methylation during lifestyle mediated weight loss.
2023 Scientific Article in Obesity Obesity 31, 2375-2385 (2023)
Who benefits most from outpatient lifestyle intervention? An IMI-SOPHIA study on pediatric individuals living with overweight and obesity.
2023 Scientific Article in European Radiology Eur. Radiol. 33, 8957-8964 (2023)
Abdominal fat quantification using convolutional networks.
2023 Review in Archives of Toxicology Arch. Toxicol. 97, 1267-1283 (2023)
Modernizing persistence-bioaccumulation-toxicity (PBT) assessment with high throughput animal-free methods.
2023 Editorial in Frontiers in Neural Circuits Front. Neural Circuits 17:1177498 (2023)
Editorial: Optogenetic and chemogenetic insights on sensory stimulus detection to motivated behaviors and reinforcement.
2023 Review in Nutrition Journal Nutr. J. 22:28 (2023)
The role of the oral microbiome in obesity and metabolic disease: Potential systemic implications and effects on taste perception.
2023 Scientific Article in Obesity Obesity 31, 2139-2149 (2023)
Reducing BMI below the obesity threshold in adolescents treated with once-weekly subcutaneous semaglutide 2.4 mg.
2023 Scientific Article in Journal of Clinical Medicine J. Clin. Med. 12:16 (2023)
Impact of optimal medical therapy on reintervention and survival rates after endovascular infrapopliteal revascularization.
2023 Scientific Article in The Lancet Regional Health - Europe Lancet Reg. Health-Eur. 30:100652 (2023)
Fasting indices of glucose-insulin-metabolism across life span and prediction of glycemic deterioration in children with obesity from new diagnostic cut-offs.
2023 Scientific Article in Clinical Neuroradiology Clin. Neuroradiol., 12 (2023)
Association of Small Fiber Function with Microvascular Perfusion of Peripheral Nerves in Patients with Type 2 Diabetes : Study using Quantitative Sensory Testing and Magnetic Resonance Neurography.
2023 Scientific Article in Hepatology Hepatology 78, 1092-1105 (2023)
Semaphorin 3C exacerbates liver fibrosis.
2023 Scientific Article in Frontiers in Endocrinology Front. Endocrin. 14:1046690 (2023)
Sciatic nerve fractional anisotropy and neurofilament light chain protein are related to sensorimotor deficit of the upper and lower limbs in patients with type 2 diabetes.
2023 Scientific Article in Molecular Metabolism Mol. Metab. 73:101729 (2023)
Diabetes increases mortality in patients with pancreatic and colorectal cancer by promoting cachexia and its associated inflammatory status.
2023 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 108, 2676-2685 (2023)
Metastatic pheochromocytoma and paraganglioma: Somatostatin receptor 2 expression, genetics, and therapeutic responses.
2023 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 108, e979-e988 (2023)
Dysmetabolism-related early sensory deficits and their relationship with peripheral neuropathy development.
2023 Scientific Article in Frontiers in Endocrinology Front. Endocrin. 14:1143799 (2023)
Six-month periodic fasting does not affect somatosensory nerve function in type 2 diabetes patients.
2023 Review in Nature Reviews - Molecular Cell Biology Nat. Rev. Mol. Cell Biol. 24, 607-632 (2023)
Exercise metabolism and adaptation in skeletal muscle.
2023 Scientific Article in Frontiers in Endocrinology Front. Endocrin. 14:1176733 (2023)
The role of proteasome activators PA28αβ and PA200 in brown adipocyte differentiation and function.
2023 Editorial in Frontiers in Endocrinology Front. Endocrin. 14:1266148 (2023)
Editorial: New insights into multiple endocrine neoplasia type 1.
2023 Scientific Article in Nature Communications Nat. Commun. 14:5060 (2023)
Simultaneous magnetic resonance imaging of pH, perfusion and renal filtration using hyperpolarized 13C-labelled Z-OMPD.
2023 Scientific Article in EMBO Reports EMBO Rep. 24:e55981 (2023)
Fasting-sensitive SUMO-switch on Prox1 controls hepatic cholesterol metabolism.
2023 Scientific Article in Cancers Cancers 15:19 (2023)
Identification of a Novel SSTR3 full agonist for the treatment of nonfunctioning pituitary adenomas.
2023 Review in Frontiers in Oncology Front. Oncol. 13:1120178 (2023)
Endometrial cancer diagnostic and prognostic algorithms based on proteomics, metabolomics, and clinical data: A systematic review.
2023 Scientific Article in EMBO Molecular Medicine EMBO Mol. Med. 15:e17209 (2023)
Hypoxia-inducible factor 1A inhibition overcomes castration resistance of prostate tumors.
2023 Scientific Article in EBioMedicine EBioMedicine 90:104516 (2023)
Elevated markers of DNA damage and senescence are associated with the progression of albuminuria and restrictive lung disease in patients with type 2 diabetes.
2023 Scientific Article in Molecular Metabolism Mol. Metab. 71:101706 (2023)
Inceptor correlates with markers of prostate cancer progression and modulates insulin/IGF1 signaling and cancer cell migration.
2023 Scientific Article in Molecular Metabolism Mol. Metab. 74:101748 (2023)
Depletion of pyruvate kinase (PK) activity causes glycolytic intermediate imbalances and reveals a PK-TXNIP regulatory axis.
2023 Scientific Article in Cell Cell 186, 3706-3725.e29 (2023)
Distinct molecular profiles of skull bone marrow in health and neurological disorders.
2023 Scientific Article in Science Science 381, 285-290 (2023)
Immune-mediated denervation of the pineal gland underlies sleep disturbance in cardiac disease.
2023 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 109, e137-e144 (2023)
Insulin resistance is associated with the capillary permeability of thigh muscles in patients with type 2 diabetes.
2023 Scientific Article in Diabetologia Diabetologia 66, 1129-1141 (2023)
The extent and magnitude of islet T cell infiltration as powerful tools to define the progression to type 1 diabetes.
2023 Scientific Article in Environmental Research Environ. Res. 232:116325 (2023)
Outdoor light at night and Children's body mass: A cross-sectional analysis in the Fr1da study.
2023 Scientific Article in BMC Medicine BMC Med. 21:190 (2023)
First-in-human, double-blind, randomized phase 1b study of peptide immunotherapy IMCY-0098 in new-onset type 1 diabetes.
2023 Scientific Article in JAMA: Journal of the American Medical Association JAMA 329, 2089-2091 (2023)
Type 1 diabetes incidence and risk in children with a diagnosis of COVID-19.
2023 Scientific Article in Pediatric Diabetes Pediatr. Diabetes 2023:11 (2023)
Dietary intake and body mass index influence the risk of islet autoimmunity in genetically at-risk children: A mediation analysis using the TEDDY Cohort.
2023 Scientific Article in Diabetes Care Diabetes Care 46, 1839-1847 (2023)
HLA genotype and probiotics modify the association between timing of solid food introduction and islet autoimmunity in the TEDDY Study.
2023 Review in Diabetes Aktuell Diabetes akt. 21, 12-28 (2023)
Früherkennung und Prävention des Typ-1-Diabetes.
2023 Scientific Article in Diabetes Care Diabetes Care 46, 1005-1013 (2023)
Abatacept for delay of type 1 diabetes progression in stage 1 relatives at risk: A randomized, double-masked, controlled trial.
2023 Review in Journal of Internal Medicine J. Intern. Med. 294, 145-158 (2023)
Possible heterogeneity of initial pancreatic islet beta-cell autoimmunity heralding type 1 diabetes.
2023 Review in Diabetologia Diabetologia 66, 1169-1178 (2023)
The countdown to type 1 diabetes: when, how and why does the clock start?
2023 Environmental Research Environ. Res. 231:116179 (2023)
Corrigendum to "Association of long-term environmental exposures in pregnancy and early life with islet autoimmunity development in children in Bavaria, Germany" [Environ. Res. 212 (2022) 113503].
2023 Scientific Article in Diabetes Care Diabetes Care 46, 1908-1915 (2023)
Gastrointestinal infections modulate the risk for insulin autoantibodies as the first-appearing autoantibody in the TEDDY Study.
2023 Scientific Article in New England Journal of Medicine, The / NEJM N. Engl. J. Med. 389, 474-475 (2023)
SARS-CoV-2 - no increased islet autoimmunity or type 1 diabetes in teens.
2023 Review in NeuroImage - a Journal of Brain Function Neuroimage 273:120057 (2023)
Not with a "zap" but with a "beep": Measuring the origins of perinatal experience.
2023 Editorial in Hepatology communications Hepat. Commun. 7:3 (2023)
Clustering NAFLD: Phenotypes of nonalcoholic fatty liver disease and their differing trajectories.
2023 Scientific Article in Journal of Lipid Research J. Lipid Res. 64:100378 (2023)
Ex vivo instability of lipids in whole blood: Preanalytical recommendations for clinical lipidomics studies.
2023 Scientific Article in Journal of Neuroscience J. Neurosci. 43, 3509-3519 (2023)
Accelerating maturation of spatial memory systems by experience – evidence from sleep oscillation signatures of memory processing.
2023 Scientific Article in Comprehensive Psychoneuroendocrinology Compr. Psychoneuroend. 14:100181 (2023)
Impact of maternal emotional state during pregnancy on fetal heart rate variability.
2023 Review in Lancet Diabetes and Endocrinology Lancet Diabet. Endocrinol. 11, 426-440 (2023)
Metabolic health and cardiometabolic risk clusters: Implications for prediction, prevention, and treatment.
2023 Scientific Article in Physiological reports Physiol. Rep. 11:e15680 (2023)
The effect of maternal pregestational diabetes on fetal autonomic nervous system.
2023 Scientific Article in Science Advances Sci. Adv. 9:eadd0433 (2023)
Analysis of volume and topography of adipose tissue in the trunk: Results of MRI of 11,141 participants in the German National Cohort.
2023 Editorial in Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet. 131, 500-503 (2023)
Insulin secretion capacity as a crucial feature to distinguish type 1 from type 2 diabetes and to indicate the need for insulin therapy - a critical discussion of the ADA/EASD consensus statement on the management of type 1 diabetes in adults.
2023 Review in Nutrients Nutrients 15:18 (2023)
Clinical pathobiochemistry of vitamin B12 deficiency: improving our understanding by exploring novel mechanisms with a focus on diabetic neuropathy.
2023 Editorial in Acta Physiologica Acta Physiol. 238:e14007 (2023)
The post-exercise paradox of reduced glucose tolerance and insulin sensitivity.
2023 Scientific Article in Diabetologia Diabetologia 66, 1501-1515 (2023)
Glucose-stimulated insulin secretion depends on FFA1 and Gq in neonatal mouse islets.
2023 Scientific Article in Science Advances Sci. Adv. 9:eadj1895 (2023)
Human REM sleep recalibrates neural activity in support of memory formation.
2023 Review in Pathophysiology Pathophysiology 30, 327-345 (2023)
Pathophysiology of red blood cell dysfunction in diabetes and its complications.
2023 Scientific Article in Cardiovascular Diabetology Cardiovasc. Diabetol. 22:211 (2023)
Clusters of prediabetes and type 2 diabetes stratify all-cause mortality in a cohort of participants undergoing invasive coronary diagnostics.
2023 Letter to the Editor in Lancet Diabetes and Endocrinology Lancet Diabet. Endocrinol. 11, 636-637 (2023)
Achieving replicable subphenotypes of adult-onset diabetes - Authors' reply.
2023 Scientific Article in FASEB Journal FASEB J. 37:e23105 (2023)
STE20-type kinases MST3 and MST4 promote the progression of hepatocellular carcinoma: Evidence from human cell culture and expression profiling of liver biopsies.
2023 Letter to the Editor in Cell Reports Medicine Cell Rep. Med. 4:101123 (2023)
A sweet spot for the sleeping brain: Linking human sleep physiology and glucoregulation.
2023 Scientific Article in Frontiers in Endocrinology Front. Endocrin. 14:1195677 (2023)
Atrial natriuretic peptide and leptin interactions in healthy men.
2023 Scientific Article in International Journal of Molecular Sciences Int. J. Mol. Sci. 24:18 (2023)
Extracellular matrix expression in human pancreatic fat cells of patients with normal glucose regulation, prediabetes and type 2 diabetes.
2023 Scientific Article in Physiology & Behavior Physiol. Behav. 270:114292 (2023)
Sweet taste preference is associated with greater hypothalamic response to glucose and longitudinal weight gain.
2023 Scientific Article in Nutrients Nutrients 15:12 (2023)
Late, but not early, night sleep loss compromises neuroendocrine appetite regulation and the desire for food.
2023 Scientific Article in Diabetes, Obesity and Metabolism Diabetes Obes. Metab. 25, 2171-2180 (2023)
Brain insulin responsiveness is linked to age and peripheral insulin sensitivity.
2023 Scientific Article in Diabetes Research and Clinical Practice Diabetes Res. Clin. Pract. 199:110636 (2023)
Circulating levels of gastrointestinal hormones in prediabetes reversing to normoglycemia or progressing to diabetes in a year-A cross-sectional and prospective analysis.
2023 Nature Biotechnology Nat. Biotechnol. 41:1026 (2023)
Author Correction: Discovery of drug-omics associations in type 2 diabetes with generative deep-learning models.
2023 Scientific Article in Frontiers in Nutrition Front. Nutr. 10:1170873 (2023)
Oral fructose intake does not improve exercise, visual, or cognitive performance during acute normobaric hypoxia in healthy humans.
2023 Scientific Article in Nature Communications Nat. Commun. 14:5062 (2023)
Genetic analysis of blood molecular phenotypes reveals common properties in the regulatory networks affecting complex traits.
2023 Review in Peptides Peptides 165:171003 (2023)
The molecular pharmacology of glucagon agonists in diabetes and obesity.
2023 Scientific Article in Molecular Metabolism Mol. Metab. 72:101714 (2023)
Neuronal loss of TRPM8 leads to obesity and glucose intolerance in male mice.
2023 Scientific Article in Nature Communications Nat. Commun. 14:1588 (2023)
Bitter taste cells in the ventricular walls of the murine brain regulate glucose homeostasis.
2023 Scientific Article in Nature Nature 615, 705-711 (2023)
The dietary sweetener sucralose is a negative modulator of T cell-mediated responses.
2023 Scientific Article in International Journal of Molecular Sciences Int. J. Mol. Sci. 24:38 (2023)
Transfer of proteins from cultured human adipose to blood cells and induction of anabolic phenotype are controlled by serum, insulin and sulfonylurea drugs.
2023 Scientific Article in Cell Metabolism Cell Metab. 35, 438-455.e7 (2023)
Estradiol regulates leptin sensitivity to control feeding via hypothalamic Cited1.
2023 Letter to the Editor in Cell Metabolism Cell Metab. 35, 377-379 (2023)
Protection from alcohol intoxication: Must be FGF21 to enter.
2023 Review in Nature metabolism Nat. Metab. 5, 933-944 (2023)
Gut hormone co-agonists for the treatment of obesity: From bench to bedside.
2023 Scientific Article in Nature metabolism Nat. Metab. 5, 945-954 (2023)
The incretin co-agonist tirzepatide requires GIPR for hormone secretion from human islets.
2023 Scientific Article in Nature metabolism Nat. Metab. 5, 861-879 (2023)
A non-coding variant linked to metabolic obesity with normal weight affects actin remodelling in subcutaneous adipocytes.
2023 Review in Biomolecules Biomolecules 13:41 (2023)
(Patho)Physiology of glycosylphosphatidylinositol-anchored proteins I: localization at plasma membranes and extracellular compartments.
2023 Scientific Article in Aging Cell Aging Cell 22:e13911 (2023)
Accelerated aging in mice with astrocytic redox imbalance as a consequence of SOD2 deletion.
2023 Review in Cell Metabolism Cell Metab. 35, 1519-1529 (2023)
GIPR/GLP-1R dual agonist therapies for diabetes and weight loss-chemistry, physiology, and clinical applications.
2023 Scientific Article in Pflügers Archiv Pflugers Arch. 475, 1149-1160 (2023)
Blood transcriptomics mirror regulatory mechanisms during hibernation-a comparative analysis of the Djungarian hamster with other mammalian species.
2023 Scientific Article in Cell Metabolism Cell Metab. 35, 1373-1389.e8 (2023)
Hepatic levels of S-adenosylmethionine regulate the adaptive response to fasting.
2023 Review in Diabetologia Diabetologia 66, 1780-1795 (2023)
Incretin hormones and type 2 diabetes.
2023 Scientific Article in Nature metabolism Nat. Metab. 5, 1364-1381 (2023)
Targeting the TCA cycle can ameliorate widespread axonal energy deficiency in neuroinflammatory lesions.
2023 Scientific Article in International Journal of Molecular Sciences Int. J. Mol. Sci. 24:20 (2023)
Innova 2020: A follow-up study of the fecal microbiota of infants using a novel infant formula between 6 months and 12 months of age.
2023 Review in Diabetologia Diabetologia 66, 1796-1808 (2023)
Gut hormone-based pharmacology: Novel formulations and future possibilities for metabolic disease therapy.
2023 Scientific Article in Cardiovascular Diabetology Cardiovasc. Diabetol. 22:217 (2023)
GIP receptor agonism improves dyslipidemia and atherosclerosis independently of body weight loss in preclinical mouse model for cardio-metabolic disease.
2023 Scientific Article in BMC Biology BMC Biol. 21:55 (2023)
TBX3 is dynamically expressed in pancreatic organogenesis and fine-tunes regeneration.
2023 Scientific Article in Science Advances Sci. Adv. 9:eadd8564 (2023)
Synthetic enforcement of STING signaling in cancer cells appropriates the immune microenvironment for checkpoint inhibitor therapy.
2023 Scientific Article in Journal of Internal Medicine J. Intern. Med. 294, 47-57 (2023)
Moderate dietary salt restriction improves blood pressure and mental well-being in patients with primary aldosteronism: The salt CONNtrol trial.
2023 Scientific Article in Life Science Alliance Life Sci. All. 6:e202201730 (2023)
Deletion of SERF2 in mice delays embryonic development and alters amyloid deposit structure in the brain.
2023 Scientific Article in Mammalian Genome Mamm. Genome 34, 244-261 (2023)
Knockout mouse models as a resource for the study of rare diseases.
2023 Editorial in Mammalian Genome Mamm. Genome 34, 105-106 (2023)
Introduction to Mammalian Genome special issue: Cardiovascular disease in the Mammalian Genome.
2023 Scientific Article in Mammalian Genome Mamm. Genome 34, 180-199 (2023)
Comprehensive ECG reference intervals in C57BL/6N substrains provide a generalizable guide for cardiac electrophysiology studies in mice.
2023 Scientific Article in Biochimica et Biophysica Acta - Molecular Basis of Disease Biochim. Biophys. Acta-Mol. Basis Dis. 1869:166760 (2023)
AOX delays the onset of the lethal phenotype in a mouse model of Uqcrh (complex III) disease.
2023 Scientific Article in Mammalian Genome Mamm. Genome 34, 200-215 (2023)
Echo2Pheno: A deep-learning application to uncover echocardiographic phenotypes in conscious mice.
2023 Scientific Article in eLife eLife 12:e88350 (2023)
The negative adipogenesis regulator Dlk1 is transcriptionally regulated by Ifrd1 (TIS7) and translationally by its orthologue Ifrd2 (SKMc15).
2023 Review in Mammalian Genome Mamm. Genome 34, 408-417 (2023)
INFRAFRONTIER: Mouse model resources for modelling human diseases.
2023 Scientific Article in American Journal of Human Genetics, The Am. J. Hum. Genet. 110, 1394-1413 (2023)
Monoallelic variation in DHX9, the gene encoding the DExH-box helicase DHX9, underlies neurodevelopment disorders and Charcot-Marie-Tooth disease.
2023 Scientific Article in PLoS ONE PLoS ONE 18:e0288542 (2023)
Standardized tissue sampling guidelines for histopathological and molecular analyses of rainbow trout (Oncorhynchus mykiss) in ecotoxicological studies.
2023 Scientific Article in Molecular Metabolism Mol. Metab. 75:101774 (2023)
Differences in DNA methylation of HAMP in blood cells predicts the development of type 2 diabetes.
2023 Scientific Article in Aging Cell Aging Cell 22:e13957 (2023)
The impact of the cardiovascular component and somatic mutations on ageing.
2023 Scientific Article in Diabetes, Obesity and Metabolism Diabetes Obes. Metab. 25, 1403-1407 (2023)
β-cell function in treatment-naïve patients with type 2 diabetes mellitus: Analyses of baseline data from 15 clinical trials.
2023 Scientific Article in Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet. 131, 13-23 (2023)
Gestational Diabetes Mellitus (GDM), diagnostics, therapy and follow-up care.
2023 Scientific Article in Nature Biotechnology Nat. Biotechnol. 41, 399-408 (2023)
Discovery of drug-omics associations in type 2 diabetes with generative deep-learning models.
2023 Scientific Article in World Journal of Pediatrics World J. Pediatr. 19, 864-872 (2023)
Serum levels of the novel adipokine isthmin-1 are associated with obesity in pubertal boys.
2023 Scientific Article in Diabetes Care Diabetes Care 46, 1014-1018 (2023)
Interaction between dietary iron intake and genetically determined iron overload: Risk of islet autoimmunity and progression to Type 1 diabetes in the TEDDY study.
2023 Scientific Article in BMC Medicine BMC Med. 21:80 (2023)
Circulating amino acid levels and colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition and UK Biobank cohorts.
2023 Scientific Article in International Journal of Molecular Sciences Int. J. Mol. Sci. 24:3962 (2023)
Clonal hematopoiesis mutations are present in atherosclerotic lesions in peripheral artery disease.
2023 Scientific Article in International Journal of Molecular Sciences Int. J. Mol. Sci. 24:20 (2023)
COBL, MKX and MYOC are potential regulators of brown adipose tissue development associated with obesity-related metabolic dysfunction in children.
2023 Scientific Article in Genes Genes 14:11 (2023)
Sex-specific effects of the genetic variant rs10487505 upstream of leptin in the development of obesity.
2023 Editorial in Lancet Diabetes and Endocrinology Lancet Diabet. Endocrinol. 11, 143-144 (2023)
Beyond genetic screening-functionality-based precision medicine in monogenic obesity.
2023 Scientific Article in Journal of Personalized Medicine J. Pers. Med. 13:12 (2023)
Effect of surgical release of entrapped peripheral nerves in sensorimotor diabetic neuropathy on pain and sensory dysfunction-study protocol of a prospective, controlled clinical trial.
2023 Scientific Article in American Journal of Human Genetics, The Am. J. Hum. Genet. 110, 475-486 (2023)
The impact of coding germline variants on contralateral breast cancer risk and survival.
2023 Scientific Article in Disease Models and Mechanisms Dis. Model. Mech. 16:dmm049770 (2023)
Knockout mice represent an important tool for the multisystemic study of human monogenic heart disease.
2023 Scientific Article in Metabolites Metabolites 13:227 (2023)
Metabolic signatures elucidate the effect of body mass index on type 2 diabetes.
2023 Scientific Article in Frontiers in Immunology Front. Immunol. 14:1112570 (2023)
Intralymphatic glutamic acid decarboxylase administration in type 1 diabetes patients induced a distinctive early immune response in patients with DR3DQ2 haplotype.
2023 Editorial in JAMA: Journal of the American Medical Association JAMA 329, 512-513 (2023)
SARS-CoV-2 infections and presymptomatic type 1 diabetes autoimmunity in children and adolescents-reply.
2023 Scientific Article in Endocrine Connections Endocr. Connect. 12:8 (2023)
Diabetes in all hospitalized cases in Germany 2015-2019 and impact of the first COVID-19 year 2020.
2023 Scientific Article in American Journal of Clinical Nutrition Am. J. Clin. Nutr. 117, 785-793 (2023)
Effect of unsaturated fat and protein intake on liver fat in people at risk of unhealthy aging: 1-year results of a randomized controlled trial.
2023 Scientific Article in Diabetes, Obesity and Metabolism Diabetes Obes. Metab. 25, 1512-1522 (2023)
Effects of finerenone in persons with CKD and T2D are independent of HbA1c at baseline, HbA1c variability, diabetes duration and insulin use at baseline.
2023 Scientific Article in Endocrinology Endocrinology 164:12 (2023)
Neuronal blockade of thyroid hormone signaling increases sensitivity to diet-induced obesity in adult male mice.
2023 Scientific Article in Diabetologia Diabetologia 66, 873-883 (2023)
Skeletal muscle and intermuscular adipose tissue gene expression profiling identifies new biomarkers with prognostic significance for insulin resistance progression and intervention response.
2023 Scientific Article in Molecular Metabolism Mol. Metab. 69:101691 (2023)
Rest phase snacking increases energy resorption and weight gain in male mice.
2023 Scientific Article in Biological Psychiatry Biol. Psychiatry 94, 424-436 (2023)
The addiction-susceptibility TaqIA/Ankyrin repeat and kinase domain containing 1 kinase (ANKK1) controls reward and metabolism through dopamine receptor type 2 (D2R)-expressing neurons.
2023 Scientific Article in Molecular and Cellular Endocrinology Mol. Cell. Endocrinol. 565:111885 (2023)
TXNIP overexpression in mice enhances streptozotocin-induced diabetes severity.
2023 Scientific Article in International Journal of Molecular Sciences Int. J. Mol. Sci. 24:13 (2023)
Antifibrotic soluble thy-1 correlates with renal dysfunction in chronic kidney disease.
2023 Scientific Article in International Journal of Molecular Sciences Int. J. Mol. Sci. 24:25 (2023)
Effects of a novel infant formula on the fecal microbiota in the first six months of life: The INNOVA 2020 Study.
2023 Scientific Article in International Journal of Obesity Int. J. Obes. 47, 313-324 (2023)
Acute and long-term exercise adaptation of adipose tissue and skeletal muscle in humans: A matched transcriptomics approach after 8-week training-intervention.
2023 Scientific Article in Nature Communications Nat. Commun. 14:709 (2023)
Adipocyte-derived extracellular vesicles increase insulin secretion through transport of insulinotropic protein cargo.
2023 Scientific Article in Cell Reports Cell Rep. 42:112088 (2023)
Thyroid hormones regulate Zfp423 expression in regionally distinct adipose depots through direct and cell-autonomous action.
2023 Scientific Article in International Journal of Obesity Int. J. Obes. 47, 306-312 (2023)
Anthropometric estimators of abdominal fat volume in adults with overweight and obesity.
2023 Scientific Article in Diabetologia Diabetologia 66, 897-912 (2023)
Islet Autoantibody Standardization Program: Interlaboratory comparison of insulin autoantibody assay performance in 2018 and 2020 workshops.
2023 Scientific Article in Frontiers in Immunology Front. Immunol. 14:1097472 (2023)
Identification of tumor antigens and immune landscapes for bladder urothelial carcinoma mRNA vaccine.
2023 Scientific Article in BMC Biology BMC Biol. 21:22 (2023)
Genome-wide screening reveals the genetic basis of mammalian embryonic eye development.
2023 Review in Cell Metabolism Cell Metab. 35, 236-252 (2023)
The role of hepatokines in NAFLD.
2023 Scientific Article in Frontiers in Endocrinology Front. Endocrin. 14:1108910 (2023)
Methylglyoxal products in pre-symptomatic type 1 diabetes.
2023 Scientific Article in PLoS ONE PLoS ONE 18:e0275123 (2023)
Gluten-free diet adherence in children with screening-detected celiac disease using a prospective birth cohort study.
2023 Scientific Article in Scientific Reports Sci. Rep. 13:1890 (2023)
Extra-viral DNA in adeno-associated viral vector preparations induces TLR9-dependent innate immune responses in human plasmacytoid dendritic cells.
2023 Scientific Article in Zeitschrift für Medizinische Physik Z. Med. Phys., DOI: 10.1016/j.zemedi.2022.12.004 (2023)
Automated shape-independent assessment of the spatial distribution of proton density fat fraction in vertebral bone marrow.
2023 Scientific Article in Frontiers in Immunology Front. Immunol. 13:1107366 (2023)
Staining of activated ß2-integrins in combination with CD137 and CD154 for sensitive identification of functional antigen-specific CD4+ and CD8+ T cells.
2023 Scientific Article in Photoacoustics Photoacoustics 29:100454 (2023)
Non-invasive multispectral optoacoustic tomography resolves intrahepatic lipids in patients with hepatic steatosis.
2023 Editorial in Frontiers in Endocrinology Front. Endocrin. 14:1136997 (2023)
Editorial: COVID-19 and diabetes, volume II.
2023 Review in Nature Protocols Nat. Protoc. 18, 1197-1242 (2023)
Whole-mouse clearing and imaging at the cellular level with vDISCO.
2023 Scientific Article in European Journal of Human Genetics Eur. J. Hum. Genet. 31, 578-587 (2023)
FANCM missense variants and breast cancer risk: A case-control association study of 75,156 European women.
2023 Scientific Article in Genome Medicine Genome Med. 15:7 (2023)
Aggregation tests identify new gene associations with breast cancer in populations with diverse ancestry.
2023 Scientific Article in American Journal of Human Genetics, The Am. J. Hum. Genet. 110, 284-299 (2023)
Loci for insulin processing and secretion provide insight into type 2 diabetes risk.
2023 Review in Journal of Clinical Investigation J. Clin. Invest. 133:4 (2023)
Dual gut hormone receptor agonists for diabetes and obesity.
2023 Scientific Article in BMC Public Health BMC Public Health 23:135 (2023)
Mental health in children and adolescents with overweight or obesity.
2023 Scientific Article in The lancet child & adolescent health Lancet Child Adolesc. Health 7, 261-268 (2023)
Islet autoantibody screening in at-risk adolescents to predict type 1 diabetes until young adulthood: A prospective cohort study.
2023 Scientific Article in Proceedings of the National Academy of Sciences of the United States of America Proc. Natl. Acad. Sci. U.S.A. 120:e2200057120 (2023)
Intranasal delivery of full-length anti-Nogo-A antibody: A potential alternative route for therapeutic antibodies to central nervous system targets.
2023 Scientific Article in Nutrients Nutrients 15:147 (2023)
Effects of a novel infant formula on weight gain, body composition, safety and tolerability to infants: The INNOVA 2020 Study.
2023 Review in Acta Physiologica Acta Physiol. 237:e13936 (2023)
When should I eat: A circadian view on food intake and metabolic regulation.
2023 Scientific Article in Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet. 131, 173-178 (2023)
Comparability of C-peptide measurements - current status and clinical relevance.
2023 Scientific Article in Pharmacological Research Pharmacol. Res. 187:106634 (2023)
Mirabegron-induced brown fat activation does not exacerbate atherosclerosis in mice with a functional hepatic ApoE-LDLR pathway.
2023Vortrag: American Diabetes Association 83rd Scientific Sessions, Jun 23, 2023 - Jun 2, San Diego Convention Center. San Diego, CA, United States. (2023)
ScRNAseq based analysis of the stromal immune cell composition in murine pre-weaning and adult white adipose tissues .
2023 Scientific Article in Nature Cell Biology Nat. Cell Biol. 25, 20–29 (2023)
Sphingolipid subtypes differentially control proinsulin processing and systemic glucose homeostasis.
2023 Editorial in Journal of Physiology - London J. Physiol.-London 601, 711-713 (2023)
From honeymoon to dysfunction: Brown fat remodeling in obesity.
2023 Scientific Article in JCI insight JCI insight 8:e163397 (2023)
TRPM7 kinase is required for insulin production and compensatory islet responses during obesity.
2023 Scientific Article in Diabetes Diabetes 72, 362-366 (2023)
Lower hepatic fat is associated with improved insulin secretion in a high-risk prediabetes subphenotype during lifestyle intervention.
2023 Scientific Article in Lancet Diabetes and Endocrinology Lancet Diabet. Endocrinol. 11, 33-41 (2023)
Pharmacogenomics of GLP-1 receptor agonists: A genome-wide analysis of observational data and large randomised controlled trials.
2023 Review in Advances in Experimental Medicine and Biology Adv. Exp. Med. Biol. 1396, 215-232 (2023)
Genome editing and protein energy malnutrition.
2023 Scientific Article in Diabetologia Diabetologia 66, 535-550 (2023)
Pancreatic alpha cell glucagon-liver FGF21 axis regulates beta cell regeneration in a mouse model of type 2 diabetes.
2023 Scientific Article in Archives of Disease in Childhood Arch. Dis. Childhood 108, 26-30 (2023)
Successful integration of newborn genetic testing into UK routine screening using prospective consent to determine eligibility for clinical trials.
2023 Scientific Article in Human Brain Mapping Hum. Brain Mapp. 44, 418-428 (2023)
The effect of hunger state on hypothalamic functional connectivity in response to food cues.
2023 Scientific Article in Molecular and Cellular Biochemistry Mol. Cell. Biochem. 478, 581-595 (2023)
Circadian disruption alters gut barrier integrity via a ß-catenin-MMP-related pathway.
2023 Other: News Item in Nature Reviews - Endocrinology Nat. Rev. Endocrinol. 19, 8–9 (2023)
SARS-CoV-2 fires up inflammation in adipose tissue.
2023 Scientific Article in Methods in Molecular Biology Methods Mol. Biol. 2589, 145-155 (2023)
Development of pyrazine-anilinobenzamides as histone deacetylase HDAC1-3 selective inhibitors and biological testing against pancreas cancer cell lines.
2023 Review in Nature Reviews - Endocrinology Nat. Rev. Endocrinol. 19, 28–45 (2023)
Endosomal trafficking in metabolic homeostasis and diseases.
2023 Scientific Article in The American Journal of Gastroenterology : AJG Am. J. Gastroenterol. 118, 539-545 (2023)
Incidence of pediatric celiac disease varies by Region: Celiac disease varies by Region.
München, Technische Universität München, Fakultät für Medizin, Diss., 2022, 118 S.
Studying mechanisms of diabetes remission following bariatric surgery.
2022 Editorial in Diabetes, Stoffwechsel und Herz Diabetes Stoffwechs. Herz 31, 345-350 (2022)
Fatty Liver and Diabetes.
2022 Nature Cardiovascular Research Nat. Cardio. Res. 1, 529-531 (2022)
Publisher Correction: Extensive identification of genes involved in congenital and structural heart disorders and cardiomyopathy (Nature Cardiovascular Research, (2022), 1, 2, (157-173), 10.1038/s44161-022-00018-8).
2022 Kardiologie Kardiologie 16, 358-371 (2022)
Positionspapier Herzinsuffizienz und Diabetes.
2022 Editorial in Metabolism and Target Organ Damage Metab. Target. Organ. Damage 2:21 (2022)
Screening for advanced liver fibrosis in overweight and obese patients with NAFLD.
2022 Letter to the Editor in Diabetologie, Die Diabetologie 18, 426-430 (2022)
Diabetes and fatty liver.
2022 Letter to the Editor in Clinical and Translational Discovery Clin. Transl. Discovery 2:e153 (2022)
Breathe and burn: Novel roles for myoglobin in thermogenesis.
In: Comprehensive Pharmacology. 2022. 326-368 ( ; 2)
Gene Therapy.
2022 Review in Diabetologie, Die Diabetologie 18, 412-417 (2022)
Lipid therapy in patients with diabetes mellitus: A joint statement by the Commission on Lipid Metabolism and the working group Heart and Diabetes of the German Diabetes Society (DDG), the Section Diabetes, Obesity and Diabetology and Metabolism of the German Society of Endocrinology (DGE), the working group Heart and Diabetes of the German Society of Cardiology (DGK) and the joint working group Heart–Hormones–Diabetes of DGK, DGE and DDG.
2022 Scientific Article in American Journal of Clinical Nutrition Am. J. Clin. Nutr. 116, 394-403 (2022)
Sources of dietary gluten in the first 2 years of life and associations with celiac disease autoimmunity and celiac disease in Swedish genetically predisposed children: The Environmental Determinants of Diabetes in the Young (TEDDY) study.
2022 Scientific Article in Trials Trials 23:414 (2022)
INNODIA Master Protocol for the evaluation of investigational medicinal products in children, adolescents and adults with newly diagnosed type 1 diabetes.
2022 Scientific Article in Deutsches Ärzteblatt international Dtsch. Arztebl. Int. 119, 765-770 (2022)
SARS-CoV-2 seroprevalence in preschool and school-age children.
2022 Scientific Article in Bioinformatics Advances Bioinfo. Adv. 2:vbac042 (2022)
Correlation-guided Network Integration (CoNI), an R package for integrating numerical omics data that allows multiform graph representations to study molecular interaction networks.
2022 Scientific Article in Metabolites Metabolites 13:15 (2022)
Exercise-induced N-lactoylphenylalanine predicts adipose tissue loss during endurance training in overweight and obese humans.
2022 Scientific Article in Proceedings of the National Academy of Sciences of the United States of America Proc. Natl. Acad. Sci. U.S.A. 119:e2204527119 (2022)
Insulin regulates neurovascular coupling through astrocytes.
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Altitude, temperature, circadian rhythms and exercise.
2022 Editorial in DDG-Informationen : Mitteilungen der Deutschen Diabetes-Gesellschaft DDG Informationen, 42-47 (2022)
Adipositas in Deutschland aus Sicht der DDG und der DAG.
2022 Editorial in DDG-Informationen : Mitteilungen der Deutschen Diabetes-Gesellschaft DDG Informationen, 241-247 (2022)
Das Deutsche Zentrum für Diabetesforschung – Aktuelles aus der Wissenschaft.
2022 Editorial in DDG-Informationen : Mitteilungen der Deutschen Diabetes-Gesellschaft DDG Informationen, 268-274 (2022)
Diabetes mellitus in Deutschland – politische Handlungsfelder 2021/22.
2022Vortrag: FEBS advanced practical course on fluorescence microscopy- Functional imaging of cellular dynamics, 17 June 2022, Amsterdam. (2022)
Inceptor: A novel inhibitor of insulin signaling.
2022 Scientific Article in Mammalian Genome Mamm. Genome 34, 229-243 (2022)
Knockout of the Complex III subunit Uqcrh causes bioenergetic impairment and cardiac contractile dysfunction.
2022 Scientific Article in Brain Sciences Brain Sci. 12:1648 (2022)
Availability of central α4β2* nicotinic acetylcholine receptors in human obesity.
2022 Scientific Article in Biomedicines Biomedicines 10:3151 (2022)
Associations of betatrophin/ANGPTL8 with septic dyslipidemia in human peritonitis: An explorative analysis.
2022 Scientific Article in Journal of Nephrology J. Nephrol. 36, 1461-1467 (2022)
Two cases of severe vitamin D3 intoxication treated with therapeutic plasma exchange and high cut-off hemodialysis.
2022 Scientific Article in Nutrients Nutrients 14:5220 (2022)
Maternal weight gain during pregnancy and the developing autonomic nervous system—possible impact of GDM.
2022 Scientific Article in BMC Neuroscience BMC Neurosci. 23:81 (2022)
Objective hearing threshold identification from auditory brainstem response measurements using supervised and self-supervised approaches.
2022 Scientific Article in Nature metabolism Nat. Metab. 4, 1697-1712 (2022)
Aberrant expression of agouti signaling protein (ASIP) as a cause of monogenic severe childhood obesity.
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Brain insulin action in the control of metabolism in humans.
2022 Scientific Article in Frontiers in Nutrition Front. Nutr. 9:992682 (2022)
Intake of slow-digesting carbohydrates is related to changes in the microbiome and its functional pathways in growing rats with obesity induced by diet.
2022 Review in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 17, 445-460 (2022)
Früherkennung und Prävention des Typ-1-Diabetes.
2022 Scientific Article in Frontiers in Endocrinology Front. Endocrin. 13:1000650 (2022)
Associations of endogenous androgens and sex hormone-binding globulin with kidney function and chronic kidney disease.
2022 Review in Mammalian Genome Mamm. Genome 34, 331-350 (2022)
A rationale for considering heart/brain axis control in neuropsychiatric disease.
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A Comparative Study on the Potential of Unsupervised Deep Learning-based Feature Selection in Radiomics.
2022Vortrag: European Islet Study Group Workshop 2022, June 13-15, 2022, Strasbourg, France. (2022)
Single-cell multiomics cross-species comparison of pancreas development.
2022Vortrag: 2022 Protein Processing, Trafficking and Secretion Gordon Research Conference, 07-17-2022, Colby-Sawyer College in New Hampshire, United States. (2022)
Inceptor is a (pro-)insulin degradation receptor.
2022 Scientific Article in BMC Women's Health BMC Womens Health 22:511 (2022)
Cancer prevention in females with and without obesity: Does perceived and internalised weight bias determine cancer prevention behaviour?
2022 Scientific Article in Clinical and translational medicine Clin. Transl. Med. 12:e1108 (2022)
Myoglobin-mediated lipid shuttling increases adrenergic activation of brown and white adipocyte metabolism and is as a marker of thermogenic adipocytes in humans.
2022 Scientific Article in Diabetologie, Die Diabetologie 19, 215-222 (2022)
Prädiabetes – eine Krankheit?
2022 Review in Diabetologie, Die Diabetologie 19, 136-143 (2022)
Do-it-yourself-Therapie für Menschen mit Typ-1-Diabetes. Ein „Citizen Science project“ zur Nutzung selbstentwickelter Technologien zur automatisierten Insulinabgabe.
2022 Scientific Article in eLife eLife 11:e82031 (2022)
T cells modulate the microglial response to brain ischemia.
2022 Review in Journal of Clinical Medicine J. Clin. Med. 11:7203 (2022)
Risk of contrast-associated acute kidney injury in patients undergoing peripheral angiography with carbon dioxide compared to iodine-containing contrast agents: A systematic review and meta-analysis.
2022 Scientific Article in Diabetes Diabetes 71, 2632-2641 (2022)
Islet autoantibody levels differentiate progression trajectories in individuals with presymptomatic type 1 diabetes.
2022 Scientific Article in BMC Endocrine Disorders BMC Endocr. Disord. 22:19 (2022)
Is staff consistency important to parents' satisfaction in a longitudinal study of children at risk for type 1 diabetes: The TEDDY study.
2022 Scientific Article in Leukemia Leukemia 37, 288-297 (2022)
A key role of the WEE1-CDK1 axis in mediating TKI-therapy resistance in FLT3-ITD positive acute myeloid leukemia patients.
2022 Scientific Article in Diabetologia Diabetologia 66, 579-589 (2022)
Serum neurofilament light chain: A novel biomarker for early diabetic sensorimotor polyneuropathy.
2022 Scientific Article in Turkish Journal of Nephrology Turk. J. Nephrol. 31, 391-392 (2022)
Widespread calcifications delineating an arterial vessel tree in a peritoneal dialysis patient.
2022 Scientific Article in HRB Open Research HRB Open Res. 4:42 (2022)
The effect of exercise interventions on inflammatory markers in major depressive disorder: Protocol for a systematic review and meta-analysis.
2022 Scientific Article in Nature metabolism Nat. Metab. 4, 1684–1696 (2022)
Mitochondrial RNA stimulates beige adipocyte development in young mice.
2022 Scientific Article in Cancers Cancers 14:5481 (2022)
Combined targeting of pathogenetic mechanisms in pancreatic neuroendocrine tumors elicits synergistic antitumor effects.
2022 Scientific Article in Journal of Clinical Medicine J. Clin. Med. 11:6762 (2022)
Diabetes and the prostate: Elevated fasting glucose, insulin resistance and higher levels of adrenal steroids in prostate cancer.
2022 Scientific Article in Magnetic Resonance in Medicine Magn. Reson. Med., DOI: 10.1002/mrm.29543 (2022)
Soy lecithin: A beneficial substance for adjusting the ADC in aqueous solutions to the values of biological tissues.
2022 Scientific Article in Scientific Reports Sci. Rep. 12:20791 (2022)
Analysis of genome-wide knockout mouse database identifies candidate ciliopathy genes.
2022 Scientific Article in Frontiers in Endocrinology Front. Endocrin. 13:1000094 (2022)
Is subcutaneous adipose tissue expansion in people living with lipedema healthier and reflected by circulating parameters?
2022 Scientific Article in Nature metabolism Nat. Metab. 4, 1591-1610 (2022)
Single-cell profiling of vascular endothelial cells reveals progressive organ-specific vulnerabilities during obesity.
2022 Scientific Article in Adipocyte Adipocyte 11, 630-642 (2022)
Associations of GHR, IGF-1 and IGFBP-3 expression in adipose tissue cells with obesity-related alterations in corresponding circulating levels and adipose tissue function in children.
2022 Scientific Article in Deutsches Ärzteblatt international Dtsch. Arztebl. Int. 119, 651-657 (2022)
Deutscher Diabetes-Risiko-Test zur Bestimmung des individuellen Typ-2-Diabetes-Risikos: 10-Jahres-Vorhersage und externe Validierungen.
2022 Scientific Article in Cell Reports Cell Rep. 41:111698 (2022)
Acute changes in systemic glycemia gate access and action of GLP-1R agonist on brain structures controlling energy homeostasis.
2022 Scientific Article in Frontiers in cell and developmental biology Front. Cell Dev. Biol. 10:965382 (2022)
Age-dependent increase of cytoskeletal components in sensory axons in human skin.
2022 Scientific Article in Brain Sciences Brain Sci. 12:1437 (2022)
Central serotonin/noradrenaline transporter availability and treatment success in patients with obesity.
2022 Scientific Article in Molecular Metabolism Mol. Metab. 66:101626 (2022)
NIK/MAP3K14 in hepatocytes orchestrates NASH to hepatocellular carcinoma progression via JAK2/STAT5 inhibition.
2022 Letter to the Editor in Signal transduction and targeted therapy Signal Transduct. Target. Ther. 7:375 (2022)
Fire up the pyre: Inosine thermogenic signaling for obesity therapy.
2022 Scientific Article in Arteriosclerosis, Thrombosis, and Vascular Biology Arterioscler. Thromb. Vasc. Biol. 43, e29-e45 (2022)
Cargo-specific role for retriever subunit VPS26C in hepatocyte lipoprotein receptor recycling to control postprandial triglyceride-rich lipoproteins.
2022 Scientific Article in Nature Communications Nat. Commun. 13:6547 (2022)
Analytical and computational workflow for in-depth analysis of oxidized complex lipids in blood plasma.
2022 Scientific Article in Frontiers in Endocrinology Front. Endocrin. 13:891442 (2022)
Advanced glycation end-products are associated with diabetic neuropathy in young adults with type 1 diabetes.
2022 Scientific Article in Nature Communications Nat. Commun. 13:6754 (2022)
Altered glycolysis triggers impaired mitochondrial metabolism and mTORC1 activation in diabetic β-cells.
2022 Scientific Article in Pediatric Diabetes Pediatr. Diabetes 23, 1707-1716 (2022)
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Author Correction: Endosomal trafficking in metabolic homeostasis and diseases (Nature Reviews Endocrinology, (2022), 10.1038/s41574-022-00737-9).
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Systematic assessment of monogenic etiology in adult-onset kidney stone formers undergoing urological intervention–evidence for genetic pretest probability.
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Correction to: Progression likelihood score identifies substages of presymptomatic type 1 diabetes in childhood public health screening.
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2022 Review in Nature metabolism Nat. Metab. 4, 1097-1108 (2022)
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Rodent models to study sodium retention in experimental nephrotic syndrome.
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Monitoring longitudinal disease progression in a novel murine Kit tumor model using high-field MRI.
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Personalized drug testing in human pheochromocytoma/paraganglioma primary cultures.
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Hepatocyte-specific activity of TSC22D4 triggers progressive NAFLD by impairing mitochondrial function.
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De-novo and depot-specific androgen production in human adipose tissue - a source of hyperandrogenism in women with obesity.
2022 Review in Diabetologie, Die Diabetologie 18, 758–768 (2022)
Molekulargenetische Diagnostik des Diabetes mellitus.
2022 Editorial in Deutsche Medizinische Wochenschrift - DMW Dtsch. Med. Wochenschr. 147, 377-378 (2022)
79-jährige Patientin mit nephrotischer Proteinurie.
2022 Review in Sleep Medicine Sleep Med. 92, 50-58 (2022)
The effect of slow-wave sleep and rapid eye-movement sleep interventions on glycaemic control: A systematic review and meta-analysis of randomised controlled trials.
2022 Scientific Article in Journal of Feline Medicine and Surgery Open Reports JFMS Open Rep. 8, 20551169221081398 (2022)
Recovery after inadvertent intramedullary microchip implantation at C1–C2 in a kitten.
2022 Scientific Article in International Journal of Molecular Sciences Int. J. Mol. Sci. 23:7418 (2022)
Biological role of the intercellular transfer of glycosylphosphatidylinositol-anchored proteins: Stimulation of lipid and glycogen synthesis.
2022 Editorial in Frontiers in Endocrinology Front. Endocrin. 13:933562 (2022)
Editorial: Covid-19 and diabetes.
2022 Scientific Article in FEBS Letters FEBS Lett. 596, 1434-1444 (2022)
Adipocyte-specific CDK7 ablation leads to progressive loss of adipose tissue and metabolic dysfunction.
2022 Scientific Article in Scientific Reports Sci. Rep. 12:4516 (2022)
Telomere length is not a main factor for the development of islet autoimmunity and type 1 diabetes in the TEDDY study.
2022 Review in Frontiers in Endocrinology Front. Endocrin. 13:838410 (2022)
Recent advances in incretin-based pharmacotherapies for the treatment of obesity and diabetes.
2022 Scientific Article in Pflügers Archiv Pflugers Arch. 474, 613-624 (2022)
Sodium retention in nephrotic syndrome is independent of the activation of the membrane-anchored serine protease prostasin (CAP1/PRSS8) and its enzymatic activity.
2022 Review in Endocrinology, Diabetes and Metabolism Endocrinol. Diabetes Metab. 5:e00330 (2022)
Managing weight and glycaemic targets in people with type 2 diabetes—How far have we come?
2022 Scientific Article in Scientific Reports Sci. Rep. 12:4795 (2022)
Shear stress switches the association of endothelial enhancers from ETV/ETS to KLF transcription factor binding sites.
2022 Scientific Article in Nature Methods Nat. Methods 19, 803-811 (2022)
Mass spectrometry-based draft of the mouse proteome.
2022 Scientific Article in Diabetes Care Diabetes Care 45, 1911-1913 (2022)
Changes in circulating miR-375-3p and improvements in visceral and hepatic fat contents in response to lifestyle interventions: The CENTRAL trial.
2022 Scientific Article in Microbiome Microbiome 10:96 (2022)
Functional changes of the gastric bypass microbiota reactivate thermogenic adipose tissue and systemic glucose control via intestinal FXR-TGR5 crosstalk in diet-induced obesity.
2022 Scientific Article in Basic Research in Cardiology Basic Res. Cardiol. 117:32 (2022)
Reduction of A-to-I RNA editing in the failing human heart regulates formation of circular RNAs.
2022 Scientific Article in Cell Reports Cell Rep. 39:110910 (2022)
ATGL-dependent white adipose tissue lipolysis controls hepatocyte PPARα activity.
2022 Scientific Article in Clinical and translational medicine Clin. Transl. Med. 12:e851 (2022)
DNA methylation patterns reflect individual's lifestyle independent of obesity.
2022 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 107, 2167-2181 (2022)
Six-month periodic fasting in patients with type 2 diabetes and diabetic nephropathy: A proof-of-concept study.
2022 Scientific Article in Nature Communications Nat. Commun. 13:3151 (2022)
Temporal changes in gastrointestinal fungi and the risk of autoimmunity during early childhood: The TEDDY study.
2022 Scientific Article in Diabetes Diabetes 71, 1937-1945 (2022)
Fat-distribution patterns and future type-2 diabetes.
2022 Scientific Article in Diabetes Care Diabetes Care 45, 1822-1832 (2022)
Maternal dietary glycemic index and glycemic load in pregnancy and offspring cord blood DNA methylation.
2022 Review in Nutrients Nutrients 14:2084 (2022)
Nutrients and the circadian clock: A partnership controlling adipose tissue function and health.
2022 Scientific Article in Human Molecular Genetics Hum. Mol. Genet. 31, 3377–3391 (2022)
Multi-ancestry genome-wide association study of gestational diabetes mellitus highlights genetic links with type 2 diabetes.
2022 Scientific Article in Scientific Reports Sci. Rep. 12:3410 (2022)
Evaluation of parameters for fetal behavioural state classification.
2022 Scientific Article in Frontiers in Bioscience Front. Biosci. 27:56 (2022)
Pre-pregnancy BMI but not mild stress directly influences Interleukin-6 levels and insulin sensitivity during late pregnancy.
2022 Scientific Article in Frontiers in Nutrition Front. Nutr. 9:808346 (2022)
High protein diets improve liver fat and insulin sensitivity by prandial but not fasting glucagon secretion in type 2 diabetes.
2022 Scientific Article in Frontiers in Neuroscience Front. Neurosci. 15:811085 (2022)
Magnetic resonance neurography reveals smoking-associated decrease in sciatic nerve structural integrity in Type 2 diabetes.
2022 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 107, 1520-1528 (2022)
Childhood height growth rate association with the risk of islet autoimmunity and development of type 1 diabetes.
2022 Scientific Article in Environmental Research Environ. Res. 212:113503 (2022)
Association of long-term environmental exposures in pregnancy and early life with islet autoimmunity development in children in Bavaria, Germany.
2022 Scientific Article in Frontiers in Immunology Front. Immunol. 13:818984 (2022)
Construction of a lactate-related prognostic signature for predicting prognosis, tumor microenvironment, and immune response in kidney renal clear cell carcinoma.
2022 Scientific Article in BMJ Open Diabetes Research & Care BMJ Open Diab. Res. Care 10:e002621 (2022)
Pre-diabetes, diabetes and fluctuations of glucose tolerance after gestational diabetes mellitus: 5-year follow-up of a contemporary, prospective study in Germany.
2022 Letter to the Editor in Journal of Cell Science J. Cell Sci. 135:jcs259793 (2022)
First person - Syed Qaaifah Gillani.
2022 Scientific Article in International Journal of Obesity Int. J. Obes. 46, 1662–1670 (2022)
Sex differences in central insulin action: Effect of intranasal insulin on neural food cue reactivity in adults with normal weight and overweight.
2022 Review in FEBS Letters FEBS Lett. 596, 2596-2616 (2022)
How to tame your genes: Mechanisms of inflammatory gene repression by glucocorticoids.
2022 Scientific Article in Biochemical and Biophysical Research Communications Biochem. Biophys. Res. Commun. 618, 46-53 (2022)
TSC22D4 promotes TGFβ1-induced activation of hepatic stellate cells.
2022 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 107, e2417-e2424 (2022)
Impaired metabolic health and low cardiorespiratory fitness independently associate with subclinical atherosclerosis in obesity.
2022 Scientific Article in Nature Cardiovascular Research Nat. Cardio. Res. 1, 157-173 (2022)
Extensive identification of genes involved in congenital and structural heart disorders and cardiomyopathy.
2022 Scientific Article in International Journal of Molecular Sciences Int. J. Mol. Sci. 23:2222 (2022)
Adipsin serum concentrations and adipose tissue expression in people with obesity and type 2 diabetes.
2022 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 107, e2425-e2430 (2022)
Incretin hypersecretion in gestational diabetes mellitus.
2022 Scientific Article in Physiological reports Physiol. Rep. 10:e15148 (2022)
No association of natural killer cell number and function in peripheral blood with overweight/obesity and metabolic syndrome in a cohort of young women.
2022 Scientific Article in Environment International Environ. Int. 164:107279 (2022)
Di-(2-ethylhexyl) phthalate substitutes accelerate human adipogenesis through PPARγ activation and cause oxidative stress and impaired metabolic homeostasis in mature adipocytes.
2022 Scientific Article in Metabolites Metabolites 12:99 (2022)
Analogues of natural chalcones as efficient inhibitors of AKR1C3.
2022 Scientific Article in Cells Cells 11:560 (2022)
Treatment of pheochromocytoma cells with recurrent cycles of hypoxia: A new pseudohypoxic in vitro model.
2022 Scientific Article in Endocrine-Related Cancer Endocr. Relat. Cancer 29, 121-128 (2022)
Spironolactone is associated with reduced mitotane levels in adrenocortical carcinoma patients.
2022 Review in Biomedicines Biomedicines 10:126 (2022)
Impact of physical activity and exercise on the epigenome in skeletal muscle and effects on systemic metabolism.
2022 Scientific Article in Metabolites Metabolites 12:445 (2022)
Effects of acute and chronic resistance exercise on the skeletal muscle metabolome.
2022 Scientific Article in Frontiers in Medicine Front. Med. 9:875430 (2022)
Obesity and impaired metabolic health increase risk of COVID-19-related mortality in young and middle-aged adults to the level observed in older people: The LEOSS Registry.
2022 Review in Trends in Endocrinology and Metabolism Trends Endocrinol. Metab. 33, 493-506 (2022)
Regulatory networks determining substrate utilization in brown adipocytes.
2022 Scientific Article in Genome Medicine Genome Med. 14:51 (2022)
Breast cancer risks associated with missense variants in breast cancer susceptibility genes.
2022 Scientific Article in Cell Reports Cell Rep. 39:110835 (2022)
Calorie restriction and calorie dilution have different impacts on body fat, metabolism, behavior, and hypothalamic gene expression.
2022 Scientific Article in Acta Diabetologica Acta Diabetol. 59, 687-696 (2022)
Intra-lymphatic administration of GAD-alum in type 1 diabetes: Long-term follow-up and effect of a late booster dose (the DIAGNODE Extension trial).
2022 Scientific Article in Journal of Magnetic Resonance Imaging J. Magn. Reson. Imaging 56:2102395 (2022)
Short-term variability of proton density fat fraction in pancreas and liver assessed by multiecho chemical-shift encoding-based MRI at 3 T.
2022 Scientific Article in Cell Reports Medicine Cell Rep. Med. 3:100477 (2022)
Four groups of type 2 diabetes contribute to the etiological and clinical heterogeneity in newly diagnosed individuals: An IMI DIRECT study.
2022 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 107, E1899-E1906 (2022)
Circulating levels of microRNA-122 and hepatic fat change in response to weight-loss interventions: CENTRAL Trial.
2022 Scientific Article in Journal of Neurophysiology J. Neurophysiol. 127, 548-558 (2022)
Intranasal orexin A modulates sympathetic vascular tone - a pilot study in healthy male humans.
2022 Scientific Article in Scientific Reports Sci. Rep. 12:504 (2022)
Endoplasmic reticulum stress and the unfolded protein response in skeletal muscle of subjects suffering from peritoneal sepsis.
2022 Scientific Article in Cell Death & Disease Cell Death Dis. 13:53 (2022)
Danger signal extracellular calcium initiates differentiation of monocytes into SPP1/osteopontin-producing macrophages.
2022 Review in Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet. 127, 2, S97-S101 (2022)
Position paper on lipid therapy in patients with diabetes mellitus.
2022 Review in Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet. 130, 1, S123-S126 (2022)
Diabetes mellitus and the heart.
2022 Scientific Article in Frontiers in Neuroscience Front. Neurosci. 15:741494 (2022)
Fractional anisotropy and troponin T parallel structural nerve damage at the upper extremities in a group of patients with prediabetes and type 2 diabetes - a study using 3T magnetic resonance neurography.
2022 Review in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 17, 382-388 (2022)
Auto-Antikörper-Diagnostik in der Diabetologie – Aktueller Stand der Analytik und klinische Anwendung in Deutschland.
2022 Scientific Article in Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet. 130, 1, S113-S116 (2022)
Diabetes and fatty Liver.
2022 Scientific Article in Cell Chemical Biology Cell Chem. Bio. 29, 680-689.e6 (2022)
An antisense transcript transcribed from Irs2 locus contributes to the pathogenesis of hepatic steatosis in insulin resistance.
2022 Scientific Article in iScience iScience 25:103680 (2022)
An adipose lncRAP2-Igf2bp2 complex enhances adipogenesis and energy expenditure by stabilizing target mRNAs.
2022 Scientific Article in Journal of Immunological Methods J. Immunol. Methods 502:113227 (2022)
Reproducibility of 10x Genomics single cell RNA sequencing method in the immune cell environment.
2022 Scientific Article in Molecular Metabolism Mol. Metab. 57:101436 (2022)
NFE2L1-mediated proteasome function protects from ferroptosis.
2022 Scientific Article in Communications Biology Comm. Biol. 5:408 (2022)
Dietary intervention improves health metrics and life expectancy of the genetically obese Titan mouse.
2022 Scientific Article in PLoS Genetics PLoS Genet. 18:e1010190 (2022)
Mice lacking the mitochondrial exonuclease MGME1 develop inflammatory kidney disease with glomerular dysfunction.
2022 Scientific Article in BMJ Open BMJ Open 12:e058268 (2022)
The German Gestational Diabetes Study (PREG), a prospective multicentre cohort study: Rationale, methodology and design.
2022 Review in Sports Medicine Sports Med. 52, 2569–2578 (2022)
Does a hypertrophying muscle fibre reprogramme its metabolism similar to a cancer cell?
2022 Scientific Article in Scientific Reports Sci. Rep. 12:2297 (2022)
Blood and adipose tissue steroid metabolomics and mRNA expression of steroidogenic enzymes in periparturient dairy cows differing in body condition.
2022 Scientific Article in Cells Cells 11:520 (2022)
Innate immune pathways promote oligodendrocyte progenitor cell recruitment to the injury site in adult Zebrafish brain.
2022 Scientific Article in Transgenic Research Transgenic Res. 31, 227-237 (2022)
Skeletal muscle phenotyping of Hippo gene-mutated mice reveals that Lats1 deletion increases the percentage of type I muscle fibers.
2022 Scientific Reports Sci. Rep. 12:6793 (2022)
Author Correction: Maternal whole blood cell miRNA-340 is elevated in gestational diabetes and inversely regulated by glucose and insulin (Scientific Reports, (2018), 8, 1, (1366), 10.1038/s41598-018-19200-9).
2022 Scientific Article in Biomedicines Biomedicines 10:616 (2022)
Bezafibrate reduces elevated hepatic fumarate in insulin-deficient mice.
2022 Scientific Article in Research in veterinary science Res. Vet. Sci. 146, 60-69 (2022)
Epaxial muscle atrophy is more evident in large dogs with intervertebral disc disease than in dogs with ischaemic myelopathy.
2022 Scientific Article in Diabetologia Diabetologia 65, 1278-1290 (2022)
Insulin allergy: A diagnostic and therapeutic strategy based on a retrospective cohort and a case–control study.
2022 Other: News Item in Nature metabolism Nat. Metab., DOI: 10.1038/s42255-022-00563-3 (2022)
Astroglial clean-up of satiety synapses.
2022 Letter to the Editor in Med (N Y) Med. 3, 279-280 (2022)
Awaking sleeping islets for a cure of diabetes.
2022 Scientific Article in PLoS ONE PLoS ONE 17:e0262330 (2022)
Association of circulating MR-proADM with all-cause and cardiovascular mortality in the general population: Results from the KORA F4 cohort study.
2022 Scientific Article in Diabetologia Diabetologia 65, 1212-1221 (2022)
Sleep deprivation prevents counterregulatory adaptation to recurrent hypoglycaemia.
2022 Scientific Article in Diabetes Diabetes 71, 1363-1370 (2022)
Circulating metabolites associate with and improve the prediction of all-cause mortality in type 2 diabetes.
2022 Review in Diabetes Diabetes 71, 610-623 (2022)
Screening for type 1 diabetes in the general population: A status report and perspective.
2022 Scientific Article in EMBO Molecular Medicine EMBO Mol. Med.:e14364 (2022)
Angpt2/Tie2 autostimulatory loop controls tumorigenesis.
2022 Scientific Article in EMBO Molecular Medicine EMBO Mol. Med.:e14797 (2022)
Parkinson's disease motor symptoms rescue by CRISPRa-reprogramming astrocytes into GABAergic neurons.
2022 Scientific Article in EMBO Molecular Medicine EMBO Mol. Med.:e14817 (2022)
Early disruption of photoreceptor cell architecture and loss of vision in a humanized pig model of usher syndromes.
2022 Scientific Article in Proceedings of the National Academy of Sciences of the United States of America Proc. Natl. Acad. Sci. U.S.A. 119:e2200083119 (2022)
Disruption of the circadian clock component BMAL1 elicits an endocrine adaption impacting on insulin sensitivity and liver disease.
2022 Scientific Article in Microbiome Microbiome 10:57 (2022)
Effects of caloric restriction on the gut microbiome are linked with immune senescence.
2022 Scientific Article in Nature Communications Nat. Commun. 13:1514 (2022)
Progression of type 1 diabetes from latency to symptomatic disease is predicted by distinct autoimmune trajectories.
2022 Scientific Article in Neuron Neuron 110, 1516-1531.e9 (2022)
Neuronal mitochondria transport Pink1 mRNA via synaptojanin 2 to support local mitophagy.
2022 Scientific Article in Basic Research in Cardiology Basic Res. Cardiol. 117:11 (2022)
Uncovering the molecular identity of cardiosphere-derived cells (CDCs) by single-cell RNA sequencing.
2022 Scientific Article in Diabetes Care Diabetes Care 45, 614-623 (2022)
Maternal glycemic dysregulation during pregnancy and neonatal blood DNA methylation: Meta-analyses of epigenome-wide association studies.
2022 Scientific Article in Cell Metabolism Cell Metab. 34, 473-486.e9 (2022)
A macrophage-hepatocyte glucocorticoid receptor axis coordinates fasting ketogenesis.
2022 Scientific Article in Cardiovascular Research Cardiovasc. Res., DOI: 10.1093/cvr/cvac022 (2022)
Properties and fate of human mesenchymal stem cells upon miRNA let-7f-promoted recruitment to atherosclerotic plaques.
2022 Scientific Article in Diabetes Care Diabetes Care 45, 837-844 (2022)
Costs of public health screening of children for presymptomatic type 1 diabetes in Bavaria, Germany.
2022 Review in Lancet Diabetes and Endocrinology Lancet Diabet. Endocrinol. 10, 221-230 (2022)
Sexual dimorphism in COVID-19: Potential clinical and public health implications.
2022 Review in Lancet Diabetes and Endocrinology Lancet Diabet. Endocrinol. 10, 284-296 (2022)
A global view of the interplay between non-alcoholic fatty liver disease and diabetes.
2022 Nature Genetics Nat. Genet. 54, 358-360 (2022)
EMPReSS: Standardized phenotype screens for functional annotation of the mouse genome (vol 37, pg 1155, 2005).
2022 Nature medicine Nat. Med. 28:599 (2022)
Author Correction: A combined risk score enhances prediction of type 1 diabetes among susceptible children.
2022 Letter to the Editor in Kidney International Kidney Int. 101, 649-650 (2022)
The authors reply.
2022 Other: News Item in Nature Reviews - Endocrinology Nat. Rev. Endocrinol. 18, 263–264 (2022)
An updated view on human neonatal thermogenesis.
2022 Scientific Article in JACC: Cardiovascular Interventions JACC-Cardiovasc. Interv. 15, 618-626 (2022)
2-year results with a sirolimus-eluting self-expanding stent for femoropopliteal lesions: The first-in-human ILLUMINA study.
2022 Scientific Article in Allergy Allergy 77, 2482-2497 (2022)
Differential effects of lung inflammation on insulin resistance in humans and mice.
2022 Other: Opinion in Diabetes Care Diabetes Care 45, 273-275 (2022)
The brains behind SGLT2 inhibition.
2022 Scientific Article in Gut (eGut) Gut 71, 2463-2480 (2022)
Impairment of gut microbial biotin metabolism and host biotin status in severe obesity: Effect of biotin and prebiotic supplementation on improved metabolism.
2022 Scientific Article in Nature metabolism Nat. Metab. 4, 90–105 (2022)
Identification of a regulatory pathway inhibiting adipogenesis via RSPO2.
2022 Letter to the Editor in Pflügers Archiv Pflugers Arch. 474, 185-186 (2022)
MALDI MSI for a fresh view on atherosclerotic plaque lipids.
2022 Scientific Article in Cell Metabolism Cell Metab. 34, 329-345.e8 (2022)
Atlas of exercise metabolism reveals time-dependent signatures of metabolic homeostasis.
2022 Scientific Article in Diabetes Care Diabetes Care 45, 624-633 (2022)
Heterogeneity of DKA incidence and age-specific clinical characteristics in children diagnosed with type 1 diabetes in the TEDDY Study.
2022 Scientific Article in Journal of Cachexia, Sarcopenia and Muscle J. Cachexia Sarcopenia Muscle 13, 976-986 (2022)
Population-based cohort imaging: skeletal muscle mass by magnetic resonance imaging in correlation to bioelectrical-impedance analysis.
2022 Scientific Article in Cell Reports Cell Rep. 38:110270 (2022)
Gut HIF2α signaling is increased after VSG, and gut activation of HIF2α decreases weight, improves glucose, and increases GLP-1 secretion.
2022 Scientific Article in Developmental Cell Dev. Cell 57, 387-397.e4 (2022)
The Lipid Droplet Knowledge Portal: A resource for systematic analyses of lipid droplet biology.
2022 Scientific Article in Nature Methods Nat. Methods 19, 159–170 (2022)
CellRank for directed single-cell fate mapping.
2022 Review in Advanced Drug Delivery Reviews Adv. Drug Deliv. Rev. 181:114110 (2022)
Delivery of miRNAs to the adipose organ for metabolic health.
2022 Scientific Article in Diabetes Diabetes 71, 566-577 (2022)
Cytotoxicity-related gene expression and chromatin accessibility define a subset of CD4+ T cells that mark progression to type 1 diabetes.
2022 Scientific Article in Cardiovascular Diabetology Cardiovasc. Diabetol. 21:6 (2022)
Fetuin-A and risk of diabetes-related vascular complications: A prospective study.
2022 Scientific Article in Xenotransplantation Xenotransplantation 29:e12719 (2022)
Transgenic pigs expressing near infrared fluorescent protein-A novel tool for noninvasive imaging of islet xenotransplants.
2022 Scientific Article in Cytokine Cytokine 150:155786 (2022)
Association of serum uromodulin with adipokines in dependence of type 2 diabetes.
2022 Scientific Article in Molecular Metabolism Mol. Metab. 56:101412 (2022)
Adipocyte-specific tribbles pseudokinase 1 regulates plasma adiponectin and plasma lipids in mice.
2022 Scientific Article in Pflügers Archiv Pflugers Arch. 474, 217-229 (2022)
Proteolytic activation of the epithelial sodium channel (ENaC) by factor VII activating protease (FSAP) and its relevance for sodium retention in nephrotic mice.
2022 Scientific Article in Cancers Cancers 14:90 (2022)
Aging aggravates cachexia in tumor-bearing mice.
2022 Scientific Article in Transplantation Proceedings Transplant. Proc. 54, 116-119 (2022)
Late onset cerebral nocardiosis in a sensitized renal transplant recipient following alemtuzumab induction: A case report.
2022 Scientific Article in Disease Models and Mechanisms Dis. Model. Mech. 15:dmm049205 (2022)
Post-synaptic scaffold protein TANC2 in psychiatric and somatic disease risk.
2022 Scientific Article in Cells Cells 11:28 (2022)
Enhancer RNA expression in response to glucocorticoid treatment in murine macrophages.
2022 Scientific Article in Clinical Cancer Research Clin. Cancer Res. 28, 1038-1052 (2022)
Therapy-related transcriptional subtypes in matched primary and recurrent head and neck cancer.
2022 Scientific Article in Cells Cells 11:42 (2022)
TNFα mediates inflammation-induced effects on PPARG splicing in adipose tissue and mesenchymal precursor cells.
2022 Scientific Article in American Journal of Physiology - Endocrinology and Metabolism Am. J. Physiol. Endocrinol. Metab. 322, E85-E100 (2022)
Susceptibility to diet-induced obesity at thermoneutral conditions is independent of UCP1.
2022 Review in Nature Reviews - Endocrinology Nat. Rev. Endocrinol. 18, 75-76 (2022)
Metabolic disorders, COVID-19 and vaccine-breakthrough infections.
2022 Other: News Item in Nature Reviews - Endocrinology Nat. Rev. Endocrinol. 18, 7-8 (2022)
Research in metabolic ageing - a tale of mice versus humans?
2022 Review in Nature Reviews - Endocrinology Nat. Rev. Endocrinol. 18, 79–80 (2022)
New insights into β-cell failure, regeneration and replacement.
2022 Review in Nature Reviews - Drug Discovery Nat. Rev. Drug Discov. 21, 201-223 (2022)
Anti-obesity drug discovery: Advances and challenges.
2022 Scientific Article in Human Molecular Genetics Hum. Mol. Genet. 31, 3367-3376 (2022)
First mitochondrial genome wide association study with metabolomics.
2022 Scientific Article in Diabetes Care Diabetes Care 45, 160-168 (2022)
Islet autoantibody type-specific titer thresholds improve stratification of risk of progression to type 1 diabetes in children.
2022 Scientific Article in Diabetes/Metabolism Research and Reviews Diabetes Metab. Res. Rev.:e3500 (2022)
Immune response differs between intralymphatic or subcutaneous administration of GAD-alum in individuals with recent onset type 1 diabetes.
2022 Scientific Article in Life Science Alliance Life Sci. All. 5:e202101164 (2022)
Bis-choline tetrathiomolybdate prevents copper-induced blood-brain barrier damage.
2022 Scientific Article in Diabetes Care Diabetes Care 45, 398-406 (2022)
Empagliflozin improves insulin sensitivity of the hypothalamus in humans with prediabetes: A randomized, double-blind, placebo-controlled, phase 2 trial.
2022 Editorial in Gut (eGut) Gut 71, 2147-2148 (2022)
Is epiploic fat the dermal fat of the intestine?
2022 Scientific Article in Diabetologie, Die Diabetologie 18, 77-86 (2022)
Laboratory diagnostics of people with diabetes.
2022 Diabetologia Diabetologia 65:257 (2022)
Correction to: Neuron-specific biomarkers predict hypo- and hyperalgesia in individuals with diabetic peripheral neuropathy.
2022 Review in Nature Reviews - Endocrinology Nat. Rev. Endocrinol. 18, 43–54 (2022)
Metabolic implications of pancreatic fat accumulation.
2022 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 107, e582-e593 (2022)
Distinct and convergent beneficial effects of estrogen and insulin on cognitive function in healthy young men.
2022 Scientific Article in Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet. 130, 393-399 (2022)
Association of serum myostatin with body weight, visceral fat volume, and high sensitivity C-reactive protein but not with muscle mass and physical fitness in premenopausal women.
2022 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 107, e836-e851 (2022)
Expression of the adipocyte progenitor markers MSCA1 and CD36 is associated with adipose tissue function in children.
2022 Scientific Article in Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet. 130, 17-21 (2022)
Influence of spinal cord stimulation on insulin sensitivity in chronic pain patients.
2022 Scientific Article in Radiation Research Radiat. Res. 197, 67-77 (2022)
Complex long-term effects of radiation on adult mouse behaviour.
2022 Scientific Article in Neuropathology and Applied Neurobiology Neuropathol. Appl. Neurobiol. 48:e12750 (2022)
N471D WASH complex subunit strumpellin knock-in mice display mild motor and cardiac abnormalities and BPTF and KLHL11 dysregulation in brain tissue.
2022 Scientific Article in Acta Pharmacologica Sinica Acta Pharmacol. Sin. 43, 111-120 (2022)
Renal effects of the serine protease inhibitor aprotinin in healthy conscious mice.
2022 Scientific Article in Radiation Research Radiat. Res. 197, 7-21 (2022)
On the nature of murine radiation-induced subcapsular cataracts: Optical coherence tomography-based fine classification, in vivo dynamics and impact on visual acuity.
2022 Scientific Article in Epigenetics Epigenetics 17, 19-31 (2022)
Maternal haemoglobin levels in pregnancy and child DNA methylation: A study in the pregnancy and childhood epigenetics consortium.
2022 Review in Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet. 130, 200-204 (2022)
Considering insulin secretory capacity as measured by a fasting c-peptide/glucose ratio in selecting glucose-lowering medications.
2022 Scientific Article in Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet. 130, 43-48 (2022)
The TUDID Study - background and design of a prospective cohort.
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Adipose Extracellular Matrix Remodeling in Obesity and Insulin Resistance.
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A sandbox for prediction and integration of DNA, RNA, and protein data in single cells.
2021 Ernährungs-Umschau Ernährungs-Umschau 68, M341-M343 (2021)
Die Operation: Ein Baustein der Adipositas-Therapie.
Masterclass in Neuroendocrinology In: Neuroanatomy of Neuroendocrine Systems. 2021. 317-346 (Mast. Neuroend. ; 12)
The Neuroanatomical Organization of Hypothalamic Feeding Circuits.
Masterclass in Neuroendocrinology In: Glial-Neuronal Signaling in Neuroendocrine Systems. 2021. 127-154 (Mast. Neuroend. ; 11)
Control of Systemic Metabolism by Astrocytes in the Brain.
In: Endocrine Surgery Comprehensive Board Exam Guide. 2021. 935–950
Multiple endocrine neoplasia type 4 (MEN 4).
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Animal welfare.
2021 Scientific Article in AMIA Annual Symposium Proceedings AMIA Annu. Symp. Proc. 2021, 754-762 (2021)
Imputing longitudinal growth data in international pediatric studies: Does CDC reference suffice?
2021 Scientific Article in Frontiers in Global Women's Health Front. Glob. Womens Health 2:807817 (2021)
Association between objectively assessed sleep and depressive symptoms during pregnancy and post-partum.
2021 Molecular Systems Biology Mol. Syst. Biol. 17:e10851 (2021)
COVID-19 Disease Map, a computational knowledge repository of virus-host interaction mechanisms (vol 17, e10387, 2021).
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CDKN1B (p27) defects leading to pituitary tumors.
München, Technische Universität, TUM School of Life Sciences, Diss., 2021, 156 S.
Development of epigenomic signatures during intergenerational inheritance of diet-induced obesity and type 2 diabetes.
Endocrinology In: Polyendocrine Disorders and Endocrine Neoplastic Syndromes. 2021. 245-274 (Endocrinology)
Multiple endocrine neoplasia-type 4 (MEN4) and other MEN1-like syndromes.
2021 Review in Hormone Research in Paediatrics Horm. Res. Paediatr. 96, 88-96 (2021)
Stress, stress reduction and obesity in childhood and adolescence.
2021 Scientific Article in Breast Cancer Research Breast Cancer Res. 23:86 (2021)
Association of germline genetic variants with breast cancer-specific survival in patient subgroups defined by clinic-pathological variables related to tumor biology and type of systemic treatment.
2021 Scientific Article in Scientific Reports Sci. Rep. 11:19787 (2021)
Germline variants and breast cancer survival in patients with distant metastases at primary breast cancer diagnosis.
2021 Scientific Article in Nature Nature 600, 500-505 (2021)
Combinatorial, additive and dose-dependent drug-microbiome associations.
2021 Review in Biomedicines Biomedicines 9:1853 (2021)
The role of physical activity in nonalcoholic and metabolic dysfunction associated fatty liver disease.
2021 Scientific Article in PLoS ONE PLoS ONE 16:e0261564 (2021)
Course of lactate, pH and base excess for prediction of mortality in medical intensive care patients.
2021 Scientific Article in Life Life 11:1393 (2021)
Physiological doses of hydroxytyrosol modulate gene expression in skeletal muscle of exercised rats.
2021 Review in Frontiers in Endocrinology Front. Endocrin. 12:765201 (2021)
Diabetic pneumopathy-a new diabetes-associated complication: Mechanisms, consequences and treatment considerations.
2021 Review in EJNMMI Research EJNMMI Res. 11:121 (2021)
Imaging pheochromocytoma in small animals: Preclinical models to improve diagnosis and treatment.
2021 Review in Reviews in Endocrine & Metabolic Disorders Rev. Endocr. Metab. Disord., DOI: 10.1007/s11154-021-09697-3 (2021)
Neurobiological regulation of eating behavior: Evidence based on non-invasive brain stimulation.
2021 Scientific Article in New England Journal of Medicine, The / NEJM N. Engl. J. Med. 385, 1451-1461 (2021)
Empagliflozin in heart failure with a preserved ejection fraction.
2021 Scientific Article in New England Journal of Medicine, The / NEJM N. Engl. J. Med. 385, 2252-2263 (2021)
Cardiovascular events with finerenone in kidney disease and type 2 diabetes.
2021 Scientific Article in Frontiers in Physiology Front. Physiol. 12:724755 (2021)
Muscle fatigue revisited - Insights from optically pumped magnetometers.
2021 Scientific Article in Journal of Immunology J. Immunol. 207, 3081-3089 (2021)
Myeloid cell-specific IL-4 receptor knockout partially protects from adipose tissue inflammation.
2021 Review in Med (N Y) Med. 2, 1138-1162 (2021)
Charting the next century of insulin replacement with cell and gene therapies.
2021 Scientific Article in Patient Education and Counseling Patient Educ. Couns. 105, 2158-2165 (2021)
Efficacy of DiaLife, an education program for relatives of adult patients with diabetes - study protocol of a cluster randomized controlled trial.
2021 Scientific Article in Frontiers in Endocrinology Front. Endocrin. 12:778875 (2021)
m6A regulators in human adipose tissue - depot-specificity and correlation with obesity.
2021 Review in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 16, 473-475 (2021)
Veranlagung und Lebensstil – die Komplexität des Diabetes mellitus – Langerhans-Medaille 2021 – eine Kurzübersicht über den Preisträger Martin Hrabě de Angelis.
2021 Scientific Article in Nature metabolism Nat. Metab. 3, 1662-1679 (2021)
Insulin signalling in tanycytes gates hypothalamic insulin uptake and regulation of AgRP neuron activity.
2021 Review in Cancer and Metastasis Reviews Cancer Metastasis Rev., DOI: 10.1007/s10555-021-10007-1 (2021)
Extracellular citrate and metabolic adaptations of cancer cells.
2021 Scientific Article in Science Advances Sci. Adv. 7:eabb3673 (2021)
Phenotypic drug screening in a human fibrosis model identified a novel class of antifibrotic therapeutics.
2021 Scientific Article in Viruses Viruses 13:2537 (2021)
Differential effect of SARS-CoV-2 spike glycoprotein 1 on human bronchial and alveolar lung mucosa models: Implications for pathogenicity.
2021 Scientific Article in Nature Nature 600, 720–726 (2021)
A hormone complex of FABP4 and nucleoside kinases regulates islet function.
2021 Scientific Article in Cells Cells 10:3443 (2021)
Tgf-β induction of mir-143/145 is associated to exercise response by influencing differentiation and insulin signaling molecules in human skeletal muscle.
2021 Review in Diabetes Aktuell Diabetes akt. 19, 318-322 (2021)
Diabetes und Fettleber.
2021 Scientific Article in International Journal of Molecular Sciences Int. J. Mol. Sci. 22:12695 (2021)
Cardioprotective effects of palmitoleic acid (C16:1n7) in a mouse model of catecholamine-induced cardiac damage are mediated by PPAR activation.
2021 Scientific Article in International Journal of Molecular Sciences Int. J. Mol. Sci. 22:12526 (2021)
Synaptotagmin-13 is a neuroendocrine marker in brain, intestine and pancreas.
2021 Review in Journal of Cellular Biochemistry J. Cell. Biochem., DOI: 10.1002/jcb.30179 (2021)
Genes controlling skeletal muscle glucose uptake and their regulation by endurance and resistance exercise.
2021 Scientific Article in Cell Reports Medicine Cell Rep. Med. 2:100434 (2021)
Deletion of pancreas-specific miR-216a reduces beta-cell mass and inhibits pancreatic cancer progression in mice.
2021 Scientific Article in BMC Genomics BMC Genomics 22:802 (2021)
Phenotype-tissue expression and exploration (PTEE) resource facilitates the choice of tissue for RNA-seq-based clinical genetics studies.
2021 Scientific Article in PLoS ONE PLoS ONE 16:e0259629 (2021)
A new mathematical approach to improve the original dietary inflammatory index (DII) calculation.
2021 Scientific Article in BMJ Open BMJ Open 11:e052449 (2021)
Supplementation with Bifidobacterium longum subspecies infantis EVC001 for mitigation of type 1 diabetes autoimmunity: the GPPAD-SINT1A randomised controlled trial protocol.
2021 Scientific Article in JCI insight JCI insight 6:e146999 (2021)
Detection of diabetes from whole-body MRI using deep learning.
2021 Scientific Article in Hippocampus Hippocampus, DOI: 10.1002/hipo.23392 (2021)
Unfolding of spatial representation at systems level in infant rats.
2021 Editorial in Diabetologie, Die Diabetologie 17, 777-779 (2021)
Mit Big Data zu einer gezielteren Diabetes-Prävention und -Therapie.
2021 Review in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 16, S215-S225 (2021)
Gestationsdiabetes mellitus (GDM), Diagnostik, Therapie und Nachsorge-Kurzfassung der S3-Leitlinie (AWMF-Registernummer: 057-008).
2021 Review in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 16, S308-S311 (2021)
Diabetes und Fettleber.
2021 Review in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 16, S312-S318 (2021)
Lipidtherapie bei Patienten mit Diabetes mellitus-Eine gemeinsame Stellungnahme der Kommission Fettstoffwechsel sowie der AG Herz und Diabetes der Deutschen Diabetes Gesellschaft (DDG), der Sektion Diabetes, Adipositas und Stoffwechsel der Deutschen Gesellschaft für Endokrinologie (DGE), der AG Herz und Diabetes der Deutschen Gesellschaft für Kardiologie (DGK) und der gemeinsamen AG Herz-Hormone-Diabetes der DGK, DGE und DDG.
2021 Review in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 16, S319-S323 (2021)
Diabetes mellitus und Herz.
2021 Scientific Article in LAB on a chip Lab Chip 21, 4685-4695 (2021)
Automated optimization of endoderm differentiation on chip.
2021 Scientific Article in Frontiers in Medicine Front. Med. 8:751277 (2021)
Differential effects of insulin-deficient diabetes mellitus on visceral vs. subcutaneous adipose tissue-multi-omics insights from the Munich MIDY pig model.
2021 Other: Opinion in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 16, 369-371 (2021)
"A Pragmatic, Randomized Clinical Trial of Gestational Diabetes Screening"-eine interdisziplinäre Stellungnahme.
2021 Scientific Article in Magnetic Resonance Materials in Physics, Biology and Medicine Magn. Reson. Mater. Phys. Biol. Med., DOI: 10.1007/s10334-021-00970-9 (2021)
A comparison of emulsifiers for the formation of oil-in-water emulsions: Stability of the emulsions within 9 h after production and MR signal properties.
2021 Scientific Article in Faculty of 1000 Research F1000 Res. 10:456 (2021)
Moving forward with forward genetics: A summary of the INFRAFRONTIER Forward Genetics Panel Discussion.
2021 Scientific Article in Nature Communications Nat. Commun. 12:6883 (2021)
Dietary essential amino acids restore liver metabolism in ovariectomized mice via hepatic estrogen receptor α.
2021 Scientific Article in Cell Reports Cell Rep. 37:110003 (2021)
ADH5-mediated NO bioactivity maintains metabolic homeostasis in brown adipose tissue.
2021 Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet. 129, e1 (2021)
Correction: Gestational diabetes mellitus (GDM), diagnostics, therapy and follow-up care.
2021 Scientific Article in Peptides Peptides 146:170677 (2021)
Calcitonin gene-related peptide exerts inhibitory effects on autophagy in the heart of mice.
2021 Scientific Article in European Eating Disorders Review Eur. Eat. Disord. Rev., DOI: 10.1002/erv.2870 (2021)
Maternal eating disorder severity is associated with increased latency of foetal auditory event-related brain responses.
2021 Scientific Article in PLoS ONE PLoS ONE 16:e0258476 (2021)
Reproducibility and discrimination of different indices of insulin sensitivity and insulin secretion.
2021 Scientific Article in Biomedicines Biomedicines 9:1452 (2021)
Chip-based sensing of the intercellular transfer of cell surface proteins: Regulation by the metabolic state.
2021 Scientific Article in Frontiers in Oncology Front. Oncol. 11:755746 (2021)
The missing link: Cre pigs for cancer research.
2021 Scientific Article in Cell Reports Medicine Cell Rep. Med. 2:100407 (2021)
AdipoAtlas: A reference lipidome for human white adipose tissue.
2021 Scientific Article in Molecular Metabolism Mol. Metab. 54:101359 (2021)
Exercise prevents fatty liver by modifying the compensatory response of mitochondrial metabolism to excess substrate availability.
2021 Scientific Article in ESC heart failure ESC Heart Fail., DOI: 10.1002/ehf2.13713 (2021)
Non-targeted metabolomics identify polyamine metabolite acisoga as novel biomarker for reduced left ventricular function.
2021 Scientific Article in Disease Models and Mechanisms Dis. Model. Mech. 14:dmm049285 (2021)
A scalable, clinically severe pig model for Duchenne muscular dystrophy.
2021 Scientific Article in Analytical Chemistry Anal. Chem. 93, 16369-16378 (2021)
Cross-laboratory standardization of preclinical lipidomics using differential mobility spectrometry and multiple reaction monitoring.
2021 Scientific Article in Frontiers in Nutrition Front. Nutr. 8:741249 (2021)
Leptin receptor-deficient db/db mice show significant heterogeneity in response to high non-heme iron diet.
2021 Scientific Article in European Journal of Nutrition Eur. J. Nutr., DOI: 10.1007/s00394-021-02687-w (2021)
Interplay between adipose tissue secreted proteins, eating behavior and obesity.
2021 Scientific Article in Frontiers in Endocrinology Front. Endocrin. 12:739021 (2021)
Role of ubiquilins for brown adipocyte proteostasis and thermogenesis.
2021 Scientific Article in Scientific Reports Sci. Rep. 11:20306 (2021)
Slow deep breathing modulates cardiac vagal activity but does not affect peripheral glucose metabolism in healthy men.
2021 Scientific Article in Cell Metabolism Cell Metab. 33, 2398-2414.e9 (2021)
Mitochondrial metabolism coordinates stage-specific repair processes in macrophages during wound healing.
2021 Scientific Article in Nature Communications Nat. Commun. 12:6486 (2021)
Elevated circulating follistatin associates with an increased risk of type 2 diabetes.
2021 Scientific Article in Nature Communications Nat. Commun. 12:6625 (2021)
scPower accelerates and optimizes the design of multi-sample single cell transcriptomic studies.
2021 Review in Obesity Reviews Obes. Rev., DOI: 10.1111/obr.13372 (2021)
The incretin/glucagon system as a target for pharmacotherapy of obesity.
2021 Scientific Article in Molecular Systems Biology Mol. Syst. Biol. 17:e10387 (2021)
COVID19 Disease Map, a computational knowledge repository of virus–host interaction mechanisms.
2021 Scientific Article in Molecular Metabolism Mol. Metab. 54:101348 (2021)
Leptin counteracts hypothermia in hypothyroidism through its pyrexic effects and by stabilizing serum thyroid hormone levels.
2021 Review in Med (N Y) Med. 2, 1120-1137 (2021)
100 Years of insulin: Lifesaver, immune target, and potential remedy for prevention.
2021 Scientific Article in Zentralblatt für Chirurgie Zent.bl. Chir. 146, 597-604 (2021)
SARS-CoV-2-Infektionen und klinische Konsequenzen bei organtransplantierten Patienten im Rahmen der ersten Ansteckungswelle in Deutschland - eine monozentrische Umfrage und ein Fallbericht.
2021 Scientific Article in Gut (eGut) Gut, DOI: 10.1136/gutjnl-2021-324603 (2021)
Multiomics reveal unique signatures of human epiploic adipose tissue related to systemic insulin resistance.
2021 Scientific Article in Frontiers in Nutrition Front. Nutr. 8:720041 (2021)
25(OH)D levels in infancy is associated with celiac disease autoimmunity in at-risk children: A case-control study.
2021 Scientific Article in Scientific Reports Sci. Rep. 11:19609 (2021)
A newly developed and externally validated non-clinical score accurately predicts 10-year cardiovascular disease risk in the general adult population.
2021 Review in Cell and Tissue Research Cell Tissue Res., DOI: 10.1007/s00441-021-03539-z (2021)
P75 neurotrophin receptor controls subventricular zone neural stem cell migration after stroke.
2021 Review in Nutrients Nutrients 13:3999 (2021)
Impact of exercise on gut microbiota in obesity.
2021 Scientific Article in EMBO Molecular Medicine EMBO Mol. Med.:e14397 (2021)
Characterising a homozygous two-exon deletion in UQCRH: Comparing human and mouse phenotypes.
2021 Review in EJNMMI Research EJNMMI Res. 11:94 (2021)
Imaging modalities for diagnosis and monitoring of cancer cachexia.
2021 Review in Journal of Physiology - London J. Physiol.-London, DOI: 10.1113/JP281979 (2021)
Adipocyte function and the development of cardiometabolic disease.
2021 Scientific Article in Frontiers in Endocrinology Front. Endocrin. 12:722656 (2021)
Plasma metabolome profiling for the diagnosis of catecholamine producing tumors.
2021 Scientific Article in Genes Genes 12:1732 (2021)
Distinct morphological and behavioural alterations in ENU-induced heterozygous Trpc7K810stop mutant mice.
2021 Review in Nature Reviews - Endocrinology Nat. Rev. Endocrinol., DOI: 10.1038/s41574-021-00577-z (2021)
Is the association between diabetes mellitus and pulmonary fibrosis real?
2021 Scientific Article in Radiology Radiology 302, 153-161 (2021)
Diffusion MRI in peripheral nerves: Optimized b values and the role of non-Gaussian diffusion.
2021 Editorial in Frontiers in Endocrinology Front. Endocrin. 12:767012 (2021)
Editorial: Footprints of immune cells in the type 1 diabetic pancreas.
2021 Scientific Article in Nature metabolism Nat. Metab. 3, 1415-1431 (2021)
Small extracellular vesicle-mediated targeting of hypothalamic AMPKα1 corrects obesity through BAT activation.
2021 Scientific Article in Scientific Reports Sci. Rep. 11:19400 (2021)
Adipose expression of CREB3L3 modulates body weight during obesity.
2021 Scientific Reports Sci. Rep. 11:20089 (2021)
Author Correction: Adipose expression of CREB3L3 modulates body weight during obesity (Scientific Reports, (2021), 11, 1, (19400), 10.1038/s41598-021-98627-z).
2021 Scientific Article in Life Science Alliance Life Sci. All. 4:e202101013 (2021)
Functional and metabolic fitness of human CD4+ T lymphocytes during metabolic stress.
2021 Other: Opinion in JAMA network open JAMA net. open 4:e2128047 (2021)
Nonnutritive sweeteners and neural reward response in women and Iidividuals with obesity.
2021 Review in Lancet Diabetes and Endocrinology Lancet Diabet. Endocrinol. 9, 786-798 (2021)
COVID-19 and metabolic disease: Mechanisms and clinical management.
2021 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 106, 2949-2961 (2021)
Central insulin modulates dopamine signaling in the human striatum.
2021 Scientific Article in Deutsches Ärzteblatt international Dtsch. Arztebl. Int. 118, 629-636 (2021)
Blutglukoseziele in der operativen Intensivmedizin.
2021 Nature metabolism Nat. Metab. 3:1433 (2021)
Publisher Correction: Revisiting energy expenditure: How to correct mouse metabolic rate for body mass.
2021 Review in Metabolites Metabolites 11:732 (2021)
Astrocyte gliotransmission in the regulation of systemic metabolism.
2021 Review in Diabetologie, Die Diabetologie 17, 780–787 (2021)
DZDconnect: Using connected data to fight diabetes.
2021 Scientific Article in STAR Protocols STAR Protoc. 2:100805 (2021)
Purification of GFP-tagged nuclei from frozen livers of INTACT mice for RNA- and ATAC-sequencing.
2021 Review in Physiology Physiology 36, 350-358 (2021)
Role of mTor signaling for tubular function and disease.
2021 Scientific Article in Diabetes, Obesity and Metabolism Diabetes Obes. Metab., DOI: 10.1111/dom.14549 (2021)
Switching the basal insulin to insulin glargine 300 U/ml in people with type 2 diabetes under basal insulin supported oral therapy: Observational trial on effectiveness and safety.
2021 Scientific Article in Transplantation Proceedings Transplant. Proc. 53, 2421-2434 (2021)
SARS-CoV-2 in solid organ transplant recipients: A structured review of 2020.
2021 Scientific Article in Nutrients Nutrients 13:3286 (2021)
The effect of dietary protein imbalance during pregnancy on the growth, metabolism and circulatory metabolome of neonatal and weaned juvenile porcine offspring.
2021 Scientific Article in Molecular Metabolism Mol. Metab. 54:101341 (2021)
Oncostatin M suppresses browning of white adipocytes via gp130-STAT3 signaling.
2021 Scientific Article in International Journal of Molecular Sciences Int. J. Mol. Sci. 22:9979 (2021)
A novel uplc-ms/ms method identifies organ-specific dipeptide profiles.
2021 Scientific Article in Kidney International Kidney Int. 100, 1227-1239 (2021)
Proteinuric chronic kidney disease is associated with altered red blood cell lifespan, deformability and metabolism.
2021 Scientific Article in BMC Pregnancy and Childbirth BMC Pregnancy Childbirth 21:628 (2021)
Acute relaxation during pregnancy leads to a reduction in maternal electrodermal activity and self-reported stress levels.
2021 Scientific Article in Endocrine Endocrine, DOI: 10.1007/s12020-021-02858-z (2021)
Pre- versus post-operative untargeted plasma nuclear magnetic resonance spectroscopy metabolomics of pheochromocytoma and paraganglioma.
2021 Scientific Article in PLoS Medicine PLoS Med. 18:e1003786 (2021)
The blood metabolome of incident kidney cancer: A case-control study nested within the MetKid consortium.
2021 Scientific Article in Neurochemistry International Neurochem. Int. 150:105174 (2021)
Determination of morphine and norlaudanosoline in murine brain regions by dispersive liquid-liquid micro-extraction and liquid chromatograpy-electrochemical detection.
2021 Scientific Article in Proceedings of the National Academy of Sciences of the United States of America Proc. Natl. Acad. Sci. U.S.A. 118:e2107665118 (2021)
Sequential in vivo labeling of insulin secretory granule pools in INS-SNAP transgenic pigs.
2021 Scientific Article in Journal of the American Society of Nephrology J. Am. Soc. Nephrol. 32, 3066-3079 (2021)
CHOP-ASO ameliorates glomerular and tubular damage on top of ACE inhibition in diabetic kidney disease.
2021 Review in Endocrine Reviews Endocr. Rev., DOI: 10.1210/endrev/bnab025 (2021)
Arcuate nucleus-dependent regulation of metabolism - pathways to obesity and diabetes mellitus.
2021 Scientific Article in ESC heart failure ESC Heart Fail., DOI: 10.1002/ehf2.13607 (2021)
Human myocardial mitochondrial oxidative capacity is impaired in mild acute heart transplant rejection.
2021 Scientific Article in Diabetologia Diabetologia, DOI: 10.1007/s00125-021-05562-9 (2021)
Rivaroxaban compared with low-dose aspirin in individuals with type 2 diabetes and high cardiovascular risk: A randomised trial to assess effects on endothelial function, platelet activation and vascular biomarkers.
2021 Scientific Article in Molecular Metabolism Mol. Metab. 54:101330 (2021)
Vertical sleeve gastrectomy triggers fast β-cell recovery upon overt diabetes.
2021 Editorial in Frontiers in Endocrinology Front. Endocrin. 12:757539 (2021)
Editorial: Intermittent fasting - mechanisms and clinical usefulness.
2021 Review in Biomolecules Biomolecules 11:1426 (2021)
Obesity–an update on the basic pathophysiology and review of recent therapeutic advances.
2021 Scientific Article in Cancers Cancers 13:4433 (2021)
Mri‐determined psoas muscle fat infiltration correlates with severity of weight loss during cancer cachexia.
2021 Scientific Article in Diabetologia Diabetologia, DOI: 10.1007/s00125-021-05557-6 (2021)
Neuron-specific biomarkers predict hypo- and hyperalgesia in individuals with diabetic peripheral neuropathy.
2021 Scientific Article in Nature Communications Nat. Commun. 12:5208 (2021)
Defining the RBPome of primary T helper cells to elucidate higher-order Roquin-mediated mRNA regulation.
2021 Scientific Article in Science Advances Sci. Adv. 7:eabi7828 (2021)
Integration of feeding behavior by the liver circadian clock reveals network dependency of metabolic rhythms.
2021 Scientific Article in Life Science Alliance Life Sci. All. 4:e202101037 (2021)
RNA sequencing reveals niche gene expression effects of beta-hydroxybutyrate in primary myotubes.
2021 Scientific Article in STAR Protocols STAR Protoc. 2:100700 (2021)
A laser-mediated photo-manipulative toolbox for generation and real-time monitoring of DNA lesions.
2021 Scientific Article in American Journal of Physiology - Renal Physiology Am. J. Physiol.-Renal Physiol. 321, F480-F493 (2021)
Experimental nephrotic syndrome leads to proteolytic activation of the epithelial sodium channel (ENaC) in the mouse kidney.
2021 Scientific Article in Learning and Memory Learn. Mem. 28, 307-318 (2021)
The effect of zolpidem on targeted memory reactivation during sleep.
2021 Scientific Article in Journal of Lipid Research J. Lipid Res. 62:100105 (2021)
A novel compound heterozygous leptin receptor mutation causes more severe obesity than in Leprdb/db mice.
2021 Scientific Article in Journal of Cachexia, Sarcopenia and Muscle J. Cachexia Sarcopenia Muscle, DOI: 10.1002/jcsm.12758 (2021)
Association of circulating PLA2G7 levels with cancer cachexia and assessment of darapladib as a therapy.
2021 Scientific Article in Disease Models and Mechanisms Dis. Model. Mech. 14:dmm049038 (2021)
Essential role of DNA-PKcs and plasminogen for the development of doxorubicin-induced glomerular injury in mice.
2021 Scientific Article in Nature metabolism Nat. Metab. 3, 1202-1216 (2021)
Diet-induced alteration of intestinal stem cell function underlies obesity and prediabetes in mice.
2021 Scientific Article in Journal of Clinical Investigation J. Clin. Invest. 131:e142202 (2021)
Hyperexcitable interneurons trigger cortical spreading depression in an Scn1a migraine model.
2021 Scientific Article in Nature Communications Nat. Commun. 12:5068 (2021)
O-GlcNAcylated p53 in the liver modulates hepatic glucose production.
2021 Scientific Article in Diabetes Diabetes 70, 2785-2795:2785-2795 (2021)
Different effects of lifestyle intervention in high- and low-risk prediabetes.
2021 Scientific Article in Radiation Oncology Radiat. Oncol. 16:159 (2021)
Development of a model for fibroblast-led collective migration from breast cancer cell spheroids to study radiation effects on invasiveness.
2021 Scientific Article in The CRISPR Journal CRISPR J. 4, 491-501 (2021)
Increasing gene editing efficiency for CRISPR-Cas9 by small RNAs in pluripotent stem cells.
2021 Scientific Article in Internist, Der Internist 62, 998-1002 (2021)
Therapie der Adipositas mit Semaglutid.
2021 Scientific Article in Scientific Reports Sci. Rep. 11:16642 (2021)
Free fatty acids, glicentin and glucose-dependent insulinotropic polypeptide as potential major determinants of fasting substrate oxidation.
2021 Scientific Article in EMBO Molecular Medicine EMBO Mol. Med. 13:e13490 (2021)
Functional multispectral optoacoustic tomography imaging of hepatic steatosis development in mice.
2021 Scientific Article in Nature Communications Nat. Commun. 12:4957 (2021)
Offspring born to influenza A virus infected pregnant mice have increased susceptibility to viral and bacterial infections in early life.
2021 Scientific Article in Nature metabolism Nat. Metab., DOI: 10.1038/s42255-021-00451-2 (2021)
Revisiting energy expenditure: How to correct mouse metabolic rate for body mass.
2021 Review in Nature Reviews - Drug Discovery Nat. Rev. Drug Discov. 20, 920–940 (2021)
Engineering islets from stem cells for advanced therapies of diabetes.
2021 Review in Metabolites Metabolites 11:474 (2021)
Signals from the circle: Tricarboxylic acid cycle intermediates as myometabokines.
2021 Nature Communications Nat. Commun. 12:4796 (2021)
Author Correction: Glucose homeostasis is regulated by pancreatic β-cell cilia via endosomal EphA-processing.
2021 Scientific Article in Diabetologia Diabetologia, DOI: 10.1007/s00125-021-05523-2 (2021)
Simplifying prediction of disease progression in pre-symptomatic type 1 diabetes using a single blood sample.
2021 Scientific Article in The journal of experimental biology J. Exp. Biol. 224:jeb242431 (2021)
Sleep and conditioning of the siphon withdrawal reflex in Aplysia.
2021 Scientific Article in Analytical Chemistry Anal. Chem. 93, 10916-10924 (2021)
Systematic, modifying group-assisted strategy expanding coverage of metabolite annotation in liquid chromatography-mass spectrometry-based nontargeted metabolomics studies.
2021 Scientific Article in Journal of Pharmaceutical and Biomedical Analysis : JPBA J. Pharm. Biomed. Anal. 205:114288 (2021)
Comparison of the metabolome in urine prior and eight weeks after radical prostatectomy uncovers pathologic and molecular features of prostate cancer.
2021 Review in Mammalian Genome Mamm. Genome, DOI: 10.1007/s00335-021-09892-2 (2021)
INFRAFRONTIER quality principles in systemic phenotyping.
2021 Review in Cells Cells 10:1822 (2021)
A narrative review on the role of AMPK on de novo lipogenesis in non-alcoholic fatty liver disease: Evidence from human studies.
2021 Scientific Article in Deutsches Ärzteblatt international Dtsch. Arztebl. Int. 118, 407-412 (2021)
Diabetes in the Hospital.
2021 Scientific Article in Molecular Metabolism Mol. Metab. 54:101334 (2021)
A point mutation in the Pdia6 gene results in loss of pancreatic β-cell identity causing overt diabetes.
2021 Scientific Article in British Journal of Pharmacology Br. J. Pharmacol., DOI: 10.1111/bph.15630 (2021)
Approved drugs ezetimibe and disulfiram enhance mitochondrial Ca2+ uptake and suppress cardiac arrhythmogenesis.
2021 Scientific Article in European Journal of Radiology Eur. J. Radiol. 142:109864 (2021)
Contrast-enhanced MRI for simultaneous evaluation of renal morphology and split renal function in living kidney donor candidates.
2021 Scientific Article in Deutsches Ärzteblatt international Dtsch. Arztebl. Int. 118, 432-433 (2021)
HbA1c measurement cannot replace an oral glucose tolerance test for the diagnosis of gestational diabetes.
2021 Other: Opinion in Nature Nature 597, 39-40 (2021)
A brain signal that coordinates thought with metabolism.
2021 Letter to the Editor in Diabetes Research and Clinical Practice Diabetes Res. Clin. Pract. 179, 109006 (2021)
No deleterious effect of an additional pregnancy on glucose metabolism in women with previous gestational diabetes mellitus. Response to Mendoza et al.
2021 Editorial in Frontiers in Endocrinology Front. Endocrin. 12:739065 (2021)
Editorial: Brown adipose tissue: From heat production in rodents to metabolic health in humans.
2021 Editorial in EMBO Molecular Medicine EMBO Mol. Med.:e14618 (2021)
Fuse your mitochondria, lose appetite: An anorexic, anti-obesity sphingolipid.
2021 Scientific Article in International Journal of Molecular Sciences Int. J. Mol. Sci. 22:7958 (2021)
Common muscle metabolic signatures highlight arginine and lysine metabolism as potential therapeutic targets to combat unhealthy aging.
2021 Review in Advanced science Adv. Sci., e2100275 (2021)
Emerging targets in type 2 diabetes and diabetic complications.
2021 Scientific Article in Diabetologia Diabetologia 64, 2247-2257 (2021)
Characteristics of children diagnosed with type 1 diabetes before vs after 6 years of age in the TEDDY cohort study.
2021 Scientific Article in Coatings Coatings 11:838 (2021)
Anethum graveolens prevents liver and kidney injury, oxidative stress and inflammation in mice exposed to nicotine perinatally.
2021 Scientific Article in Deutsches Ärzteblatt international Dtsch. Arztebl. Int. 118, 367-372 (2021)
Diabetic ketoacidosis at manifestation of type 1 diabetes in childhood and adolescence.
2021 Scientific Article in European Journal of Radiology Eur. J. Radiol. 142:109845 (2021)
Quantification of liver and muscular fat using contrast-enhanced Dual Source Dual Energy Computed Tomography compared to an established multi-echo Dixon MRI sequence.
2021 Scientific Article in Acta Diabetologica Acta Diabetol., DOI: 10.1007/s00592-021-01772-0 (2021)
Dose-dependent effects of insoluble fibre on glucose metabolism: A stratified post hoc analysis of the Optimal Fibre Trial (OptiFiT).
2021 Scientific Article in Environment International Environ. Int. 156:106730 (2021)
Alternatives for the worse: Molecular insights into adverse effects of bisphenol a and substitutes during human adipocyte differentiation.
2021 Scientific Article in Nutrients Nutrients 13:2499 (2021)
Leptin improves parameters of brown adipose tissue thermogenesis in lipodystrophic mice.
2021 Scientific Article in European Journal of Heart Failure Eur. J. Heart Fail. 23, 1633-1644 (2021)
Proteomics to improve phenotyping in obese patients with heart failure with preserved ejection fraction.
2021 Nature Communications Nat. Commun. 12:4528 (2021)
Publisher Correction: Cellular and physiological circadian mechanisms drive diurnal cell proliferation and expansion of white adipose tissue.
2021 Review in Monatsschrift Kinderheilkunde Mon.schr. Kinderheilkd. 169, 922–929 (2021)
Nicht immer Typ 1 – seltene Diabetesformen bei Kindern.
2021 Nature Communications Nat. Commun. 12:4521 (2021)
Author Correction: PDX1LOW MAFALOW β-cells contribute to islet function and insulin release.
2021 Nature Cell Biology Nat. Cell Biol., DOI: 10.1038/s41556-021-00735-5 (2021)
Publisher Correction: Epithelial cell plasticity drives endoderm formation during gastrulation.
2021 Scientific Article in Diabetes Diabetes 70, 2092-2106 (2021)
Profiles of glucose metabolism in different prediabetes phenotypes, classified by fasting glycemia, 2-hour OGTT, glycated hemoglobin, and 1-hour OGTT: An IMI DIRECT study.
2021 Scientific Article in Cell Metabolism Cell Metab. 33, 1685-1700.e9 (2021)
Liver-fibrosis-activated transcriptional networks govern hepatocyte reprogramming and intra-hepatic communication.
2021 Scientific Article in NeuroImage - a Journal of Brain Function Neuroimage 240:118378 (2021)
Dynamics of nonlinguistic statistical learning: From neural entrainment to the emergence of explicit knowledge.
2021 Scientific Article in Journal of Nephrology J. Nephrol. 35, 311–316 (2021)
Intraperitoneal extension of the peritoneal dialysis catheter-a new technique for catheter implantation in patients with obesity.
2021 Scientific Article in Metabolites Metabolites 11:405 (2021)
Respiratory parameters for the classification of dysfunctional insulin secretion by pancreatic islets.
2021 Scientific Article in Antioxidants Antioxidants 10:1103 (2021)
Nox4 maintains blood pressure during low sodium diet.
2021 Scientific Article in Transplant international Transpl. Int. 34, 1959-1970 (2021)
Dynamics of glucose metabolism after liver transplantation: Prediabetes as a window of opportunity for patient survival and long-term kidney function.
2021 Scientific Article in Frontiers in Molecular Biosciences Front. Mol. Biosci. 8:689799 (2021)
Whole-slide image analysis of human pancreas samples to elucidate the immunopathogenesis of type 1 diabetes using the QuPath software.
2021 Scientific Article in Clinical Kidney Journal Clin. Kidney J. 14, 1618-1625 (2021)
Serum uromodulin is inversely associated with biomarkers of subclinical inflammation in the population-based KORA F4 study.
2021 Journal of Nutritional Biochemistry, The J. Nutr. Biochem. 97:108807 (2021)
Corrigendum to "Dietary protein dilution limits dyslipidemia in obesity through FGF21-driven fatty acid clearance" [The Journal of Nutritional Biochemistry 57 (2018) 189-196].
2021 Review in Frontiers in Immunology Front. Immunol. 12:683091 (2021)
Means, motive, and opportunity: Do non-islet-reactive infiltrating T cells contribute to autoimmunity in type 1 diabetes?
2021 Scientific Article in Diabetes Care Diabetes Care 44, 2269-2276 (2021)
Islet autoimmunity and HLA markers of presymptomatic and clinical type 1 diabetes: Joint analyses of prospective cohort studies in Finland, Germany, Sweden, and the U.S.
2021 Scientific Article in Appetite Appetite 166:105476 (2021)
Competing influences on healthy food choices: Mindsetting versus contextual food cues.
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Resting-state functional connectivity of the human hypothalamus.
2021 Review in Nutrition Nutrition 89:111348 (2021)
Resolution of severe hepatosteatosis in a cystic fibrosis patient with multifactorial choline deficiency: A case report.
2021 Scientific Article in Communications Biology Comm. Biol. 4:826 (2021)
Deletion of the diabetes candidate gene Slc16a13 in mice attenuates diet-induced ectopic lipid accumulation and insulin resistance.
2021 Communications Biology Comm. Biol. 4:890 (2021)
Publisher Correction: Deletion of the diabetes candidate gene Slc16a13 in mice attenuates diet-induced ectopic lipid accumulation and insulin resistance.
2021 Scientific Article in Clinical and translational medicine Clin. Transl. Med. 11:e470 (2021)
Human and mouse non-targeted metabolomics identify 1,5-anhydroglucitol as SGLT2-dependent glycemic marker.
2021 Scientific Article in Advanced science Adv. Sci. 8:e2101281 (2021)
Reduced acrolein detoxification in akr1a1a zebrafish mutants causes impaired insulin receptor signaling and microvascular alterations.
2021 Editorial in Frontiers in Endocrinology Front. Endocrin. 12:722790 (2021)
Editorial: Stem cells in endocrine tumors.
2021 Scientific Article in Biomolecules Biomolecules 11:1023 (2021)
Synthetic material abdominal swabs reduce activation of platelets and leukocytes compared to cotton materials.
2021 Scientific Article in Molecular Metabolism Mol. Metab. 53, 101295 (2021)
Correlation guided Network Integration (CoNI) reveals novel genes affecting hepatic metabolism.
2021 Scientific Article in Cancers Cancers 13:3097 (2021)
Gender-specific efficacy revealed by head-to-head comparison of pasireotide and octreotide in a representative in vivo model of nonfunctioning pituitary tumors.
2021 Editorial in Molecular Metabolism Mol. Metab. 50:101274 (2021)
NAFLD - A rising metabolic disease.
2021 Scientific Article in Nature biomedical engineering Nat. Bio. Eng. 5, 897-913 (2021)
Single-cell-resolved differentiation of human induced pluripotent stem cells into pancreatic duct-like organoids on a microwell chip.
2021 Scientific Article in Nature biomedical engineering Nat. Bio. Eng. 5, 1246-1260 (2021)
T cells armed with C-X-C chemokine receptor type 6 enhance adoptive cell therapy for pancreatic tumours.
2021 Scientific Article in EMBO Reports EMBO Rep.:e52553 (2021)
Residual pluripotency is required for inductive germ cell segregation.
2021 Scientific Article in Cancers Cancers 13:2843 (2021)
Elevated expression of the rage variant-v in sclc mitigates the effect of chemotherapeutic drugs.
2021 Scientific Article in Genome Medicine Genome Med. 13:105 (2021)
Circulating bacterial signature is linked to metabolic disease and shifts with metabolic alleviation after bariatric surgery.
2021 Scientific Article in Pediatric obesity Pediatr. Obes. 16:e12822 (2021)
Elevated transaminases potentiate the risk for emerging dysglycemia in children with overweight and obesity.
2021 Editorial in Journal of Magnetic Resonance Imaging J. Magn. Reson. Imaging 55, 541-542 (2021)
Editorial for "Concentration of gallbladder phosphatidylcholine in cholangiopathies: A 31 P MR spectroscopy pilot study".
2021 Scientific Article in Non-coding RNA Non-coding RNA 7:32 (2021)
Changes of the tRNA modification pattern during the development of Dictyostelium discoideum.
2021 Scientific Article in Nature Communications Nat. Commun. 12:3482 (2021)
Cellular and physiological circadian mechanisms drive diurnal cell proliferation and expansion of white adipose tissue.
2021 Scientific Article in Molecular Metabolism Mol. Metab. 53:101262 (2021)
Hemostatic alterations linked to body fat distribution, fatty liver and insulin resistance.
Methods in Molecular Biology In: Mitochondrial Medicine. 2021. 69-89 (Methods Mol. Biol. ; 2277)
Drug discovery assay to identify modulators of the mitochondrial Ca2+ uniporter.
2021 Scientific Article in European Journal of Epidemiology Eur. J. Epidemiol. 36, 1143-1155 (2021)
Meta-analysis of epigenome-wide association studies of carotid intima-media thickness.
2021 Scientific Article in American Journal of Human Genetics, The Am. J. Hum. Genet. 108, 1190-1203 (2021)
Functional annotation of the 2q35 breast cancer risk locus implicates a structural variant in influencing activity of a long-range enhancer element.
2021 Scientific Article in Diabetes Care Diabetes Care 44, 1992-1999 (2021)
Epigenome-wide association study reveals methylation loci associated with offspring gestational diabetes mellitus exposure and maternal methylome.
2021 Review in Analytical and Bioanalytical Chemistry Anal. Bioanal. Chem. 413, 5567-5585 (2021)
From bedside to bench—practical considerations to avoid pre-analytical pitfalls and assess sample quality for high-resolution metabolomics and lipidomics analyses of body fluids.
2021 Scientific Article in Methods and Protocols Methods Protoc. 4:633909 (2021)
Development of an optimized clearing protocol to examine adipocyte subpopulations in white adipose tissue.
2021 Review in Advanced Therapeutics Adv. Therap. 4:2100040 (2021)
Engineering gene therapy: Advances and barriers.
2021 Scientific Article in Nature Cell Biology Nat. Cell Biol. 23, 692-703 (2021)
Epithelial cell plasticity drives endoderm formation during gastrulation.
2021 Review in Clinical Kidney Journal Clin. Kidney J. 14, 1691-1693 (2021)
Successful long-term management of recurrent focalsegmental glomerulosclerosis after kidneytransplantation with costimulation blockade.
2021 Scientific Article in NeuroImage - a Journal of Brain Function Neuroimage 237:118207 (2021)
Predictors of real-time fMRI neurofeedback performance and improvement – A machine learning mega-analysis.
2021 Scientific Article in Journal of Clinical Medicine J. Clin. Med. 10:1982 (2021)
Comparison of premixed human insulin 30/70 to biphasic aspart 30 in well-controlled patients with type 2 diabetes using continuous glucose monitoring.
2021 Scientific Article in Cellular Signalling Cell. Signal. 84:110037 (2021)
Multifaceted control of mRNA translation machinery in cancer.
2021 Scientific Article in Cell Death & Disease Cell Death Dis. 12:516 (2021)
Let-7f miRNA regulates SDF-1α- and hypoxia-promoted migration of mesenchymal stem cells and attenuates mammary tumor growth upon exosomal release.
2021 Scientific Article in Developmental Cognitive Neuroscience Dev. Cogn. Neurosci . 49:100964 (2021)
Magnetoencephalographic signatures of conscious processing before birth.
2021 Scientific Article in Nature Communications Nat. Commun. 12:2911 (2021)
A BAFF/APRIL axis regulates obesogenic diet-driven weight gain.
2021 Nature Nature 593:E14 (2021)
Author Correction: Auto-aggressive CXCR6+ CD8 T cells cause liver immune pathology in NASH.
2021 Scientific Article in eLife eLife 10:e63294 (2021)
Introduction to the EQIPD quality system.
2021 Scientific Article in Developmental Cell Dev. Cell 56, 1727-1741.e7 (2021)
RANK links senescence to stemness in the mammary epithelia, delaying tumor onset but increasing tumor aggressiveness.
2021 Review in Best Practice and Research Clinical Endocrinology and Metabolism Best Pract. Res. Clin. Endocrinol. Metab. 35:101546 (2021)
Exposure to endocrine-disrupting compounds such as phthalates and bisphenol A is associated with an increased risk for obesity.
2021 Scientific Article in STAR Protocols STAR Protoc. 2:100609 (2021)
Protocol for using heterologous spike-ins to normalize for technical variation in chromatin immunoprecipitation.
2021 Scientific Article in Communications Biology Comm. Biol. 4:666 (2021)
Aberrant activity of mitochondrial NCLX is linked to impaired synaptic transmission and is associated with mental retardation.
2021 Scientific Article in Nature Communications Nat. Commun. 12:2876 (2021)
NBR1 is a critical step in the repression of thermogenesis of p62-deficient adipocytes through PPARγ.
2021 Communications Biology Comm. Biol. 4:755 (2021)
Author Correction: Aberrant activity of mitochondrial NCLX is linked to impaired synaptic transmission and is associated with mental retardation (Communications Biology, (2021), 4, 1, (666), 10.1038/s42003-021-02114-0).
2021 Scientific Article in Advanced science Adv. Sci. 8:2100626 (2021)
Functional genomic screening during somatic cell reprogramming identifies DKK3 as a roadblock of organ regeneration.
2021 Scientific Article in JMIR MHEALTH AND UHEALTH JMIR Mhealth Uhealth 9:e26163 (2021)
A smartphone app (TRIANGLE) to change cardiometabolic risk behaviors in women following gestational diabetes mellitus: Intervention mapping approach.
2021 Scientific Article in BMC Genomics BMC Genomics 22:339 (2021)
Disentangling the aging gene expression network of termite queens.
2021 Scientific Article in International Journal of Molecular Sciences Int. J. Mol. Sci. 22:4998 (2021)
Is LRP2 involved in leptin transport over the blood-brain barrier and development of obesity?
2021 Scientific Article in Diabetes Aktuell Diabetes akt. 19, 82-85 (2021)
Folgeerkrankungen des Diabetes mellitus.
2021 Scientific Article in Diabetes Aktuell Diabetes akt. 19, 67-70 (2021)
Diabetes und nicht-alkoholische Fettleber-Erkrankungen.
2021 Scientific Article in Diabetes Aktuell Diabetes akt. 19, 72-75 (2021)
Insulinwirkung und -resistenz im Gehirn.
2021 Scientific Article in Diabetes Aktuell Diabetes akt. 19, 57-60 (2021)
Prävention des Typ-2-Diabetes.
2021 Scientific Article in Diabetes, Obesity and Metabolism Diabetes Obes. Metab. 23, 1868–1878 (2021)
Distribution patterns of intramyocellular and extramyocellular fat by magnetic resonance imaging in subjects with diabetes, prediabetes and normoglycaemic controls.
2021 Scientific Article in Diabetes Aktuell Diabetes akt. 19, 86-89 (2021)
Schutz und Regeneration der Betazellen.
2021 Scientific Article in Diabetologia Diabetologia 64, 1850-1865 (2021)
HAND2 is a novel obesity-linked adipogenic transcription factor regulated by glucocorticoid signalling.
2021 Scientific Article in Nature Communications Nat. Commun. 12:2999 (2021)
Orphan GPR116 mediates the insulin sensitizing effects of the hepatokine FNDC4 in adipose tissue.
2021 Letter to the Editor in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 16, 194-195 (2021)
Kommentar.
2021Vortrag: SSIB 2021, 12-15 July 2021, Online. (2021)
The effect of hunger state on hypothalamus functional connectivity in response to food cues.
2021Vortrag: SSIB 2021, 12-15 July 2021, Online. (2021)
Sex and obesity differentially influence central insulin action to food cues.
2021Vortrag: EASD 2021, 27 September-01 October 2021, Online. (2021)
Effect of a hypercaloric diet on brain insulin sensitivity and liver fat in normal-weight men.
2021 Scientific Article in Molecular Nutrition and Food Research Mol. Nutr. Food Res. 65:2000991 (2021)
Effects of insoluble cereal fibre on body fat distribution in the optimal fibre trial (OptiFiT).
2021 Review in International Journal of Molecular Sciences Int. J. Mol. Sci. 22:6176 (2021)
Hypothalamic astrocytes as a specialized and responsive cell population in obesity.
2021 Scientific Article in Diabetes Aktuell Diabetes akt. 19, 62-65 (2021)
Einfluss von Genetik und Epigenetik auf die Entstehung von Diabetes.
2021 Scientific Article in Liver International Liver Int. 41, 2101-2111 (2021)
Effects of lifestyle interventions on epigenetic signatures of liver fat: CENTRAL randomized controlled trial.
2021 Scientific Article in Cell Metabolism Cell Metab. 33, 1155-1170.e10 (2021)
Obesity-associated hyperleptinemia alters the gliovascular interface of the hypothalamus to promote hypertension.
2021 Review in Diabetes Diabetes 70, 1038-1050 (2021)
Altered β-cell prohormone processing and secretion in type 1 diabetes.
2021 Review in Frontiers in Immunology Front. Immunol. 12:667989 (2021)
Neoepitopes in type 1 diabetes: Etiological insights, biomarkers and therapeutic targets.
2021 Scientific Article in Frontiers in Immunology Front. Immunol. 12:656451 (2021)
Potential mimicry of viral and pancreatic β cell antigens through non-spliced and cis-spliced zwitter epitope candidates in type 1 diabetes.
2021 Scientific Article in JAMA network open JAMA net. open 4:e218505 (2021)
An empirically derived definition of metabolically healthy obesity based on risk of cardiovascular and total mortality.
2021 Scientific Article in Scientific Reports Sci. Rep. 11:8843 (2021)
Liver fat scores do not reflect interventional changes in liver fat content induced by high-protein diets.
2021 Scientific Article in Brain, Behavior and Immunity Brain Behav. Immun. 95, 429-443 (2021)
Type I interferon mediated induction of somatostatin leads to suppression of ghrelin and appetite thereby promoting viral immunity in mice.
2021 Scientific Article in Adipocyte Adipocyte 10, 216-231 (2021)
Cleavage of the vaspin N-terminus releases cell-penetrating peptides that affect early stages of adipogenesis and inhibit lipolysis in mature adipocytes.
2021 Scientific Article in Molecular Metabolism Mol. Metab. 51:101235 (2021)
Iron aggravates hepatic insulin resistance in the absence of inflammation in a novel db/db mouse model with iron overload.
2021 Scientific Article in American Journal of Clinical Nutrition Am. J. Clin. Nutr. 114, 134-142 (2021)
Associations of breastfeeding with childhood autoimmunity, allergies, and overweight: The Environmental Determinants of Diabetes in the Young (TEDDY) study.
2021 Scientific Article in Food and Chemical Toxicology Food Chem. Toxicol. 152:112216 (2021)
Bisphenol F and bisphenol S promote lipid accumulation and adipogenesis in human adipose-derived stem cells.
2021 Nature Cell Biology Nat. Cell Biol. 23, 566-576 (2021)
Author Correction: Non-canonical Wnt/PCP signalling regulates intestinal stem cell lineage priming towards enteroendocrine and Paneth cell fates.
2021 Scientific Article in Photoacoustics Photoacoustics 22:100263 (2021)
Croconaine-based nanoparticles enable efficient optoacoustic imaging of murine brain tumors.
2021 Review in Diabetologie, Die Diabetologie 17, 538–548 (2021)
Gestationsdiabetes mellitus (GDM), Diagnostik, Therapie und Nachsorge.Praxisempfehlung – Kurzfassung der S3-Leitlinie (AWMF-Registernummer: 057-008).
2021 Review in Consciousness and cognition Conscious. Cogn. 91:103117 (2021)
The first prior: From co-embodiment to co-homeostasis in early life.
2021 Scientific Article in Science Advances Sci. Adv. 7:eabg6424 (2021)
Disruption of paternal circadian rhythm affects metabolic health in male offspring via nongerm cell factors.
2021 Scientific Article in Mammalian Genome Mamm. Genome 32, 332-349 (2021)
A comprehensive phenotypic characterization of a whole-body Wdr45 knock-out mouse.
2021 Letter to the Editor in Med (N Y) Med. 2, 571-572 (2021)
A public health antibody screening indicates a marked increase of SARS-CoV-2 exposure rate in children during the second wave.
2021 Review in Diabetologia Diabetologia 64, 1461-1479 (2021)
Liver-targeting drugs and their effect on blood glucose and hepatic lipids.
2021 Scientific Article in Journal of Neuroscience J. Neurosci. 41, 4212-4222 (2021)
Cell-type specific dynamics of calcium activity in cortical circuits over the course of slow wave sleep and rapid eye movement sleep.
2021 Scientific Article in Gastroenterology Gastroenterology 161, 910-923.e19 (2021)
The colorectal cancer lipidome - identification of a robust tumor-specific lipid species signature.
2021 Scientific Article in FASEB Journal FASEB J. 35:e21572 (2021)
Fibroblast growth factor induced Ucp1 expression in preadipocytes requires PGE2 biosynthesis and glycolytic flux.
2021 Scientific Article in Biomedicines Biomedicines 9:345 (2021)
The effect of FGF21 and its genetic variants on food and drug cravings, adipokines and metabolic traits.
2021 Scientific Article in Comprehensive Physiology Compr. Physiol. 11, 1759-1783 (2021)
Glucagon's metabolic action in health and disease.
2021 Scientific Article in Science Translational Medicine Sci. Transl. Med. 13:eabd5666 (2021)
Transcriptional networks in at-risk individuals identify signatures of type 1 diabetes progression.
2021 Review in Molecular and Cellular Endocrinology Mol. Cell. Endocrinol. 531:111312 (2021)
Retinol-binding protein 4 in obesity and metabolic dysfunctions.
2021 Scientific Article in Thrombosis and Haemostasis Thromb. Haemost. 121, 1464-1475 (2021)
Methylglyoxal drives a distinct, nonclassical macrophage activation status.
2021 Scientific Article in Breast Cancer Research Breast Cancer Res. 23:42 (2021)
RANK signaling increases after anti-HER2 therapy contributing to the emergence of resistance in HER2-positive breast cancer.
2021 Scientific Article in ACS infectious diseases ACS Infect. Dis. 7, 1596-1606 (2021)
Multiplexed serum antibody screening platform using virus extracts from endemic Coronaviridae and SARS-CoV-2.
2021 Scientific Article in EMBO Journal, The EMBO J., e106777 (2021)
PRMT1 promotes the tumor suppressor function of p14ARF and is indicative for pancreatic cancer prognosis.
2021 Scientific Article in Cell Stem Cell Cell Stem Cell 28, 1566-1581.e8 (2021)
Activation of HERV-K(HML-2) disrupts cortical patterning and neuronal differentiation by increasing NTRK3.
2021 Scientific Article in Sleep Sleep 44:zsab056 (2021)
Occipital sleep spindles predict sequence learning in a visuo-motor task.
2021 Scientific Article in Nature Nature 592, 444-449 (2021)
Auto-aggressive CXCR6+ CD8 T cells cause liver immune pathology in NASH.
2021 Scientific Article in Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet. 129, 1, S9-S19 (2021)
Gestational diabetes mellitus (GDM), diagnostics, therapy and follow-up care. Practice recommendation - Summary of the S3 guideline (AWMF register number: 057–008).
2021 Scientific Article in Diabetologia Diabetologia 64, 1604-1612 (2021)
Maternal food consumption during late pregnancy and offspring risk of islet autoimmunity and type 1 diabetes.
2021 Review in Diabetologie, Die Diabetologie 17, 448–451 (2021)
Diabetes mellitus and the heart.
2021 Scientific Article in Diabetologia Diabetologia 64, 1358–1374 (2021)
The hepatokine fetuin-A disrupts functional maturation of pancreatic beta cells.
2021 Scientific Article in Journal of Molecular and Cellular Cardiology J. Mol. Cell. Cardiol. 156, 45-56 (2021)
Creld1 regulates myocardial development and function.
2021 Review in Frontiers in Endocrinology Front. Endocrin. 12:616506 (2021)
Impaired intestinal barrier and tissue bacteria: Pathomechanisms for metabolic diseases.
2021 Scientific Article in Frontiers in Neuroscience Front. Neurosci. 15:642589 (2021)
Diffusion tensor imaging of the sciatic nerve as a surrogate marker for nerve functionality of the upper and lower limb in patients with diabetes and prediabetes.
2021 Scientific Article in Diabetologie, Die Diabetologie 17, 307–310 (2021)
Diabetes and fatty liver.
2021 Scientific Article in Diabetologie, Die Diabetologie 17, 293–298 (2021)
Lipidtherapie bei Patienten mit Diabetes mellitus: Eine gemeinsame Stellungnahme der Kommission Fettstoffwechsel sowie der AG Herz und Diabetes der Deutschen Diabetes Gesellschaft (DDG), der Sektion Diabetologie und Stoffwechsel der Deutschen Gesellschaft für Endokrinologie (DGE), der AG Herz und Diabetes der Deutschen Gesellschaft für Kardiologie (DGK) und der gemeinsamen AG Herz – Hormone – Diabetes der DGK, DGE und DDG.
2021 Scientific Article in Biomedicines Biomedicines 9:277 (2021)
Interaction of full-length glycosylphosphatidylinositol-anchored proteins with serum proteins and their translocation to cells in vitro depend on the (Pre-)diabetic state in rats and humans.
2021 Scientific Article in Journal of Biological Chemistry, The J. Biol. Chem. 296:100361 (2021)
Disruption of the integrin-linked kinase (ILK) pseudokinase domain affects kidney development in mice.
München, Technische Universität, Fakultät Wissenschaftszentrum Weihenstephan, Diss., 2021, 111 S.
The role of TGFβ1 and microRNAs in skeletal muscle cell metabolism and differentiation.
2021 Scientific Article in Kidney International Kidney Int. 99, 1031-1032 (2021)
The Case | A 74-year-old liver transplant recipient with nephrotic-range proteinuria.
2021 Review in Journal of Neuroendocrinology J. Neuroendocrinol. 33:e12953 (2021)
Insulin action on astrocytes: From energy homeostasis to behaviour.
2021 Scientific Article in Advanced healthcare materials Adv. Healthc. Mater. 10:e2002115 (2021)
Facile synthesis of a croconaine-based nanoformulation for optoacoustic imaging and photothermal therapy.
2021 Scientific Article in Nature Communications Nat. Commun. 12:1588 (2021)
Asc-1 regulates white versus beige adipocyte fate in a subcutaneous stromal cell population.
2021 Scientific Article in Pediatric Diabetes Pediatr. Diabetes 22, 717-728 (2021)
Parental monitoring for type 1 diabetes in genetically at-risk young children: The TEDDY study.
2021 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 106, 1576-1584 (2021)
Low-density lipoprotein cholesterol is associated with insulin secretion.
2021 Scientific Article in Biology of Reproduction Biol. Reprod. 104, 1249-1261 (2021)
Anatomical and cellular heterogeneity in the mouse oviduct- its potential roles in reproduction and preimplantation development.
2021 Nature Nature 592:E1 (2021)
Author Correction: Inceptor counteracts insulin signalling in β-cells to control glycaemia.
2021 Review in International Journal of Molecular Sciences Int. J. Mol. Sci. 22:2756 (2021)
Omics approaches in adipose tissue and skeletal muscle addressing the role of extracellular matrix in obesity and metabolic dysfunction.
2021 Scientific Article in Nature Communications Nat. Commun. 12:1041 (2021)
Pharmacological but not physiological GDF15 suppresses feeding and the motivation to exercise.
2021 Scientific Article in Molecular Metabolism Mol. Metab. 49:101188 (2021)
CD81 marks immature and dedifferentiated pancreatic β-cells.
2021 Scientific Article in Endocrine-Related Cancer Endocr. Relat. Cancer 28, 213-224 (2021)
Transcriptomic landscape of radiation-induced murine thyroid proliferative lesions.
2021 Other: Opinion in Hormone and Metabolic Research Horm. Metab. Res. 53, 204-206 (2021)
The transCampus metabolic training programme explores the link of SARS-CoV-2 virus to metabolic disease.
2021 Other: Opinion in Nature metabolism Nat. Metab. 3, 289-292 (2021)
Consequences of the COVID-19 pandemic for patients with metabolic diseases.
2021 Review in International Journal of Molecular Sciences Int. J. Mol. Sci. 22:4475 (2021)
Leptin receptor compound heterozygosity in humans and animal models.
2021 Scientific Article in International Journal of Molecular Sciences Int. J. Mol. Sci. 22:4353 (2021)
Effects of whole-body adenylyl cyclase 5 (Adcy5) deficiency on systemic insulin sensitivity and adipose tissue.
2021 Review in Antioxidants Antioxidants 10:622 (2021)
Contribution of adipose tissue oxidative stress to obesity-associated diabetes risk and ethnic differences: Focus on women of African ancestry.
2021 Scientific Article in NeuroImage: Clinical Neuroimage: Clin. 30:102679 (2021)
Diminished prefrontal cortex activation in patients with binge eating disorder associates with trait impulsivity and improves after impulsivity-focused treatment based on a randomized controlled IMPULS trial.
2021 Scientific Article in American Journal of Physiology - Cell Physiology Am. J. Physiol.-Cell Physiol. 320, C1000-C1012 (2021)
Pancreatic fat cells of humans with type 2 diabetes display reduced adipogenic and lipolytic activity.
2021 Review in Nature Reviews - Endocrinology Nat. Rev. Endocrinol. 17, 276-295 (2021)
Lipid and glucose metabolism in white adipocytes: Pathways, dysfunction and therapeutics.
2021 Scientific Article in Science Advances Sci. Adv. 7:eabd6527 (2021)
Islet expression of type I interferon response sensors is associated with immune infiltration and viral infection in type 1 diabetes.
2021 Scientific Article in Diabetes Care Diabetes Care 44, 2260-2268 (2021)
An age-related exponential decline in the risk of multiple islet autoantibody seroconversion during childhood.
2021 Scientific Article in ESC heart failure ESC Heart Fail. 8, 938-942 (2021)
Low-fat hypocaloric diet reduces neprilysin in overweight and obese human subjects.
2021 Scientific Article in Acta Physiologica Acta Physiol. 232:e13640 (2021)
Zymogen-locked mutant prostasin (Prss8) leads to incomplete proteolytic activation of the epithelial sodium channel (ENaC) and severely compromises triamterene tolerance in mice.
2021 Review in Nature metabolism Nat. Metab. 3, 299-308 (2021)
POMC neuronal heterogeneity in energy balance and beyond: An integrated view.
2021 Scientific Article in Clinical Epigenetics Clin. Epigenet. 13:48 (2021)
Lifestyle weight-loss intervention may attenuate methylation aging: The CENTRAL MRI randomized controlled trial.
2021 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 106, E3198-E3207 (2021)
Lifestyle intervention improves prothrombotic coagulation profile in individuals at high-risk for type 2 diabetes.
2021 Scientific Article in BMC Pediatrics BMC Pediatr. 21:111 (2021)
Body composition in term offspring after maternal gestational diabetes does not predict postnatal hypoglycemia.
2021 Nature Nature 589, E6 (2021)
Publisher Correction: Inhibition of LTβR signalling activates WNT-induced regeneration in lung (Nature, (2020), 588, 7836, (151-156), 10.1038/s41586-020-2882-8).
2021 Nature Nature 592:E8 (2021)
Publisher Correction: LifeTime and improving European healthcare through cell-based interceptive medicine (Nature, (2020), 587, 7834, (377-386), 10.1038/s41586-020-2715-9).
2021 Scientific Article in European Journal of Nutrition Eur. J. Nutr. 60, 3499-3504 (2021)
Similar dietary regulation of IGF-1- and IGF-binding proteins by animal and plant protein in subjects with type 2 diabetes.
2021 Scientific Article in Nature Communications Nat. Commun. 12:1152 (2021)
Exploring beyond clinical routine SARS-CoV-2 serology using MultiCoV-Ab to evaluate endemic coronavirus cross-reactivity.
2021 Scientific Article in Neuroendocrinology Neuroendocrinology 111, 263-272 (2021)
Lipid droplets accumulate in the hypothalamus of mice and humans with and without metabolic diseases.
2021 Letter to the Editor in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 16, 105-105 (2021)
Kommentar.
2021 Nature Communications Nat. Commun. 12:1804 (2021)
Author Correction: Endogenous FGF21-signaling controls paradoxical obesity resistance of UCP1-deficient mice (Nature Communications, (2020), 11, 1, (624), 10.1038/s41467-019-14069-2).
2021 Scientific Article in BMJ Open Ophthalmology BMJ Open Ophthalmol. 6:e000688 (2021)
Testing for SARS-CoV-2 seroprevalence: Experiences of a tertiary eye centre.
2021 Scientific Article in Frontiers in Immunology Front. Immunol. 12:626308 (2021)
Integrin activation enables sensitive detection of functional CD4+ and CD8+ T cells: Application to characterize SARS-CoV-2 immunity.
2021 Scientific Article in Metabolism: clinical and experimental Metabolism 119:154776 (2021)
Determinants of hepatic insulin clearance - results from a Mendelian Randomization study.
2021 Review in Diabetologie, Die Diabetologie 17, 382–390 (2021)
Erhöhte Darmpermeabilität: Pathomechanismus für metabolische Erkrankungen?
2021 Scientific Article in Cell calcium Cell Calcium 95:102364 (2021)
Towards a systems-level understanding of mitochondrial biology.
2021 Scientific Article in Biomedicines Biomedicines 9:131 (2021)
Role of kallikrein 7 in body weight and fat mass regulation.
2021 Nature Communications Nat. Commun. 12:989 (2021)
Publisher Correction: Loss of POMC-mediated antinociception contributes to painful diabetic neuropathy.
2021 Scientific Article in Scientific Reports Sci. Rep. 11:3627 (2021)
Children's erythrocyte fatty acids are associated with the risk of islet autoimmunity.
2021 Scientific Article in Nutrients Nutrients 13:556 (2021)
No effect of lifestyle intervention during third trimester on brain programming in fetuses of mothers with gestational diabetes.
2021 Scientific Article in Molecules Molecules 26:1403 (2021)
Tart cherry juice and seeds affect pro-inflammatory markers in visceral adipose tissue of high-fat diet obese rats.
2021 Scientific Article in International Journal of Molecular Sciences Int. J. Mol. Sci. 22:3434 (2021)
Generation of a novel nkx6-1 venus fusion reporter mouse line.
2021 Scientific Article in PLoS ONE PLoS ONE 16:e0248594 (2021)
Unbiased analysis of obesity related, fat depot specific changes of adipocyte volumes and numbers using light sheet fluorescence microscopy.
2021 Review in CNS drugs. CNS Drugs 35, 21-37 (2021)
Intranasal insulin for Alzheimer's disease.
2021 Scientific Article in Clinical Pharmacology & Therapeutics : CPT Clin. Pharmacol. Ther. 110, 149-158 (2021)
Genetic variation in sodium-glucose cotransporter 2 and heart failure.
2021 Review in International Journal of Molecular Sciences Int. J. Mol. Sci. 22:1500 (2021)
Does C-C motif chemokine ligand 2 (CCL2) link obesity to a pro-inflammatory state?
2021 Scientific Article in Cell Reports Cell Rep. 34:108742 (2021)
The glucocorticoid receptor recruits the COMPASS complex to regulate inflammatory transcription at macrophage enhancers.
2021 Review in Trends in Cell Biology Trends Cell Biol. 31, 345-358 (2021)
Lipid droplet contact sites in health and disease.
2021 Review in Nature Genetics Nat. Genet. 53, 416-419 (2021)
A resource of targeted mutant mouse lines for 5,061 genes.
2021 Scientific Article in Physiological research Physiol. Res. 70, 227-236 (2021)
Analysis of the sex-specific variability of blood parameters in C3H inbred mice by using data from a long-term, high-throughput project.
2021 Scientific Article in International Journal of Molecular Sciences Int. J. Mol. Sci. 22:1571 (2021)
Treatment-induced neuropathy in diabetes (Tind)—developing a disease model in type 1 diabetic rats.
2021 Scientific Article in Endocrinology Endocrinology 162:bqab017 (2021)
Diabetes type 1 negatively influences Leydig cell function in rats which is partially reversible by insulin treatment.
2021 Scientific Article in Molecular Metabolism Mol. Metab. 49:101181 (2021)
Spatiotemporal GLP-1 and GIPR receptor signaling and trafficking/recycling dynamics induced by selected receptor mono- and dual-agonists.
2021 Scientific Article in Journal of Clinical Medicine J. Clin. Med. 10:411 (2021)
Detection and characterization of phosphorylation, glycosylation, and fatty acid bound to fetuin A in human blood.
2021 Scientific Article in JCI insight JCI insight 6:e136083 (2021)
The longevity gene mIndy (I’m Not Dead, Yet) affects blood pressure through sympathoadrenal mechanisms.
2021 Letter to the Editor in Molecular Metabolism Mol. Metab. 45:101159 (2021)
Divide et impera: How mitochondrial fission in astrocytes rules obesity.
2021 Scientific Article in Nature metabolism Nat. Metab. 3, 149-165 (2021)
SARS-CoV-2 infects and replicates in cells of the human endocrine and exocrine pancreas.
2021 Scientific Article in Nature Communications Nat. Commun. 12:674 (2021)
PDX1LOW MAFALOW β-cells contribute to islet function and insulin release.
2021 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 106, 1460-1471 (2021)
A pathophysiology of type 2 diabetes unrelated to metabolic syndrome.
2021 Scientific Article in Diabetologia Diabetologia 64, 1079-1092 (2021)
Oral insulin immunotherapy in children at risk for type 1 diabetes in a randomised controlled trial.
2021 Review in Diabetologie, Die Diabetologie 17, 141–148 (2021)
Inflammation: Zwischen Adipositas, Diabetes und Sport.
2021 Scientific Article in Diabetologie, Die Diabetologie 17, 26-31 (2021)
Neue Subtypen bei Prädiabetes.
2021 Scientific Article in Nutrients Nutrients 13:395 (2021)
Vitamin B12 supplementation in diabetic neuropathy: A 1-year, randomized, double-blind, placebo-controlled trial.
2021 Review in Journal of Neuroendocrinology J. Neuroendocrinol. 33:e12934 (2021)
Intranasal insulin.
2021 Scientific Article in Frontiers in Psychology Front. Psychol. 11:607070 (2021)
Vast amounts of encoded items nullify but do not reverse the effect of sleep on declarative memory.
2021 Scientific Article in Thrombosis and Haemostasis Thromb. Haemost. 121, 782-791 (2021)
Specific point-of-care testing of coagulation in patients treated with dabigatran.
2021 Scientific Article in Journal of Chromatography J. Chromatogr. B 1165:122553 (2021)
Determination of 3-iodothyronamine (3-T1AM) in mouse liver using liquid chromatography-tandem mass spectrometry.
2021 Scientific Article in Diabetes Diabetes 70, 303-312 (2021)
Emerging role of bone morphogenetic protein 4 in metabolic disorders.
2021 Scientific Article in International Journal of Obesity Int. J. Obes. 45, 840–849 (2021)
Reduced metabolic efficiency in sedentary eucaloric conditions predicts greater weight regain in adults with obesity following sustained weight loss.
2021 Review in Molecular Metabolism Mol. Metab. 47:101169 (2021)
A guide to understanding endoplasmic reticulum stress in metabolic disorders.
2021 Scientific Article in Microvascular Research Microvasc. Res. 135:104131 (2021)
Leptin promotes adipocytes survival in non-vascularized fat grafting via perfusion increase.
2021 Scientific Article in Molecular Metabolism Mol. Metab. 45:101147 (2021)
Active integrins regulate white adipose tissue insulin sensitivity and brown fat thermogenesis.
2021 Scientific Article in Cell Reports Cell Rep. 34:108624 (2021)
Endogenous fatty acid synthesis drives brown adipose tissue involution.
2021 Scientific Article in Monatsschrift Kinderheilkunde Mon.schr. Kinderheilkd. 169, 451–460 (2021)
Kann die Ketoacidose bei pädiatrischen Patienten mit Manifestation eines Diabetes mellitus Typ 1 vermieden werden? Lehren aus der COVID-19-Pandemie.
2021 Scientific Article in Cancers Cancers 13:126 (2021)
Mutation of the cell cycle regulator p27kip1 drives pseudohypoxic pheochromocytoma development.
2021 Scientific Article in PLoS ONE PLoS ONE 16:e0242830 (2021)
Balancing the brain of offenders with psychopathy? Resting state EEG and electrodermal activity after a pilot study of brain self-regulation training.
Methods in Molecular Biology In: Proteomic Profiling. 2021. 433-442 (Methods Mol. Biol. ; 2261)
Methods for proteomics-based analysis of the human muscle secretome using an in vitro exercise model.
2021 Scientific Article in Nature Nature 590, 326–331 (2021)
Inceptor counteracts insulin signalling in β-cells to control glycaemia.
2021 Scientific Article in FASEB Journal FASEB J. 35:e21302 (2021)
Systemic Jak1 activation provokes hepatic inflammation and imbalanced FGF23 production and cleavage.
2021 Scientific Article in Experimental Eye Research Exp. Eye Res. 204:108432 (2021)
Ionising radiation causes vision impairment in neonatal B6C3F1 mice.
2021 Scientific Article in Diabetologia Diabetologia 64, 591-602 (2021)
First-appearing islet autoantibodies for type 1 diabetes in young children: Maternal life events during pregnancy and the child’s genetic risk.
2021 Scientific Article in Nature metabolism Nat. Metab. 3, 394–409 (2021)
Liver alanine catabolism promotes skeletal muscle atrophy and hyperglycaemia in type 2 diabetes.
2021 Scientific Article in Frontiers in cell and developmental biology Front. Cell Dev. Biol. 9:641410 (2021)
TBL1XR1 ensures balanced neural development through NCOR complex-mediated regulation of the MAPK pathway.
2021 Scientific Article in Cell Metabolism Cell Metab. 33, 833-844.e5 (2021)
The glucose-dependent insulinotropic polypeptide (GIP) regulates body weight and food intake via CNS-GIPR signaling.
2021 Scientific Article in EMBO Molecular Medicine EMBO Mol. Med.:e12461 (2021)
Combination therapies induce cancer cell death through the integrated stress response and disturbed pyrimidine metabolism.
2021 Scientific Article in Life Science Alliance Life Sci. All. 4:e202000898 (2021)
Lipocalin 13 enhances insulin secretion but is dispensable for systemic metabolic control.
2021 Scientific Reports Sci. Rep. 11:3582 (2021)
Author Correction: Edgetic perturbation signatures represent known and novel cancer biomarkers (Scientific Reports, (2020), 10, 1, (4350), 10.1038/s41598-020-61422-3).
2021 Scientific Article in Metabolites Metabolites 11:89 (2021)
Validation of candidate phospholipid biomarkers of chronic kidney disease in hyperglycemic individuals and their organ-specific exploration in leptin receptor-deficient db/db mouse.
2021 Scientific Article in Clinical Kidney Journal Clin. Kidney J. 14, 269-276 (2021)
Urinary fetuin-A peptides as a new marker for impaired kidney function in patients with type 2 diabetes.
2021 Scientific Article in Cell Reports Cell Rep. 34:108748 (2021)
Dynamic adoption of anergy by antigen-exhausted CD4+ T cells.
2021 Scientific Article in Clinical Kidney Journal Clin. Kidney J. 14, 205-211 (2021)
Serum uromodulin and decline of kidney function in older participants of the population-based KORA F4/FF4 study.
2021 Scientific Article in Radiology. Artificial intelligence Radiol. Artif. Intell. 2:e200010 (2021)
Fully automated and standardized segmentation of adipose tissue compartments via deep learning in 3D whole-body MRI of epidemiological cohort studies.
2021 Review in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 16, 63-69 (2021)
Neue Klassifikation des Diabetes mellitus – Anforderungen an Labormessgrößen.
2021 Scientific Article in Nature Communications Nat. Commun. 12:426 (2021)
Loss of POMC-mediated antinociception contributes to painful diabetic neuropathy.
2021 Review in Nature Reviews - Endocrinology Nat. Rev. Endocrinol. 17, 135–149 (2021)
Global pandemics interconnected - obesity, impaired metabolic health and COVID-19.
2021 Scientific Article in Diabetes Care Diabetes Care 44, 774-780 (2021)
Durable effects of iGlarLixi up to 52 weeks in type 2 diabetes: The LixiLan-G Extension Study.
2021 Scientific Article in Nature medicine Nat. Med. 27, 49-57 (2021)
Pathophysiology-based subphenotyping of individuals at elevated risk for type 2 diabetes.
2021 Scientific Article in Nature Cell Biology Nat. Cell Biol. 23, 23-31 (2021)
Non-canonical Wnt/PCP signalling regulates intestinal stem cell lineage priming towards enteroendocrine and Paneth cell fates.
2021 Scientific Article in Nature Structural & Molecular Biology Nat. Struct. Mol. Biol. 28, 143–151 (2021)
Imbalances in the eye lens proteome are linked to cataract formation.
2021 Scientific Article in Cellular Immunology Cell. Immunol. 361:104276 (2021)
Extracellular vesicles released by myeloid-derived suppressor cells from pregnant women modulate adaptive immune responses.
2021 Scientific Article in PLoS Genetics PLoS Genet. 16:e1009190 (2021)
Mouse mutant phenotyping at scale reveals novel genes controlling bone mineral density.
2021 Scientific Article in Psychotherapeut Psychotherapeut 66, 28–34 (2021)
Stigmatisierung und Diskriminierung von Patient*innen mit Adipositas.
2021 Scientific Article in Metabolism: clinical and experimental Metabolism 116:154438 (2021)
Identification of a novel leptin receptor (LEPR) variant and proof of functional relevance directing treatment decisions in patients with morbid obesity.
2021 Review in Medical Hypotheses Med. Hypotheses 146:110474 (2021)
Long distance running – Can bioprofiling predict success in endurance athletes?
2021 Scientific Article in Diabetes Diabetes 70, 752-758 (2021)
One in ten CD8+ cells in the pancreas of living individuals with recent onset type 1 diabetes recognizes the preproinsulin epitope PPI15-24.
2021 Scientific Article in Journal of Proteome Research J. Proteome Res. 20, 1005-1014 (2021)
Metabolite triplet in serum improves the diagnostic accuracy of prediabetes and diabetes screening.
2021 Review in Trends in Pharmacological Sciences Trends Pharmacol. Sci. 42, 85-95 (2021)
Pharmacological targeting of endoplasmic reticulum stress in pancreatic beta cells.
2021 Scientific Article in Stem Cell Research Stem Cell Res. 50:102126 (2021)
Generation of a heterozygous C-peptide-mCherry reporter human iPSC line (HMGUi001-A-8).
2021 Scientific Article in Journal of Steroid Biochemistry and Molecular Biology, The J. Steroid Biochem. Mol. Biol. 206:105790 (2021)
Homology modeling meets site-directed mutagenesis: An ideal combination to elucidate the topology of 17β-HSD2.
2021 Scientific Article in Diabetes Research and Clinical Practice Diabetes Res. Clin. Pract. 171:108543 (2021)
No deleterious effect of an additional pregnancy on glucose metabolism in women with previous gestational diabetes mellitus.
2021 Scientific Article in Thyroid Thyroid 31, 519-527 (2021)
Effects of hyperthyroidism on adipose tissue activity and distribution in adults.
2021 Scientific Article in Diabetes Diabetes 70, 282-292 (2021)
Plasma metabolome and circulating vitamins stratified onset age of an initial islet autoantibody and progression to type 1 diabetes: The TEDDY Study.
2021 Scientific Article in Med (N Y) Med. 2, 149-163.e4 (2021)
Public health antibody screening indicates a six-fold higher SARS-CoV-2 exposure rate than reported cases in children.
2021 Scientific Article in Diabetes Diabetes 70, 91-98 (2021)
Small amounts of dietary medium-chain fatty acids protect against insulin resistance during caloric excess in humans.
2021 Scientific Article in Diabetologia Diabetologia 64, 512-520 (2021)
The liver–alpha cell axis associates with liver fat and insulin resistance: A validation study in women with non-steatotic liver fat levels.
2021 Scientific Article in Diabetes Diabetes 70, 616-626 (2021)
CaM kinase II-δ is required for diabetic hyperglycemia and retinopathy but not nephropathy.
2021 Editorial in Nature Reviews - Endocrinology Nat. Rev. Endocrinol. 17, 73–74 (2021)
Shortening the paths to type 1 diabetes mellitus prevention.
2021 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 106, e982-e989 (2021)
Elevated circulating glutamate associates with subclinical atherosclerosis independently of established risk markers: A cross-sectional study.
2021 Scientific Article in Life Science Alliance Life Sci. All. 4:e202000924 (2021)
Identification and characterization of distinct brown adipocyte subtypes in C57BL/6J mice.
2021 Scientific Article in International Journal of Radiation Biology Int. J. Radiat. Biol. 97, 156-169 (2021)
Dose-dependent long-term effects of a single radiation event on behaviour and glial cells.
2021 Scientific Article in Cancer Immunology, Immunotherapy Cancer Immunol. Immunother. 70, 1263-1275 (2021)
Noninvasive, longitudinal imaging-based analysis of body adipose tissue and water composition in a melanoma mouse model and in immune checkpoint inhibitor-treated metastatic melanoma patients.
2021 Scientific Article in Journal of Nutritional Biochemistry, The J. Nutr. Biochem. 87:108516 (2021)
Short-term high-fat feeding induces a reversible net decrease in synaptic AMPA receptors in the hypothalamus.
2021 Scientific Article in Electrochimica Acta Electrochim. Acta 365:137326 (2021)
Electroactive microorganisms in mouse feces.
2021 Scientific Article in Diabetes, Obesity and Metabolism Diabetes Obes. Metab. 23, 195-207 (2021)
Plasma proteome profiles treatment efficacy of incretin dual agonism in diet-induced obese female and male mice.
2021 Scientific Article in Journal of Sleep Research J. Sleep Res. 30, e13204 (2021)
Pregnant women do not display impaired memory formation across one night of sleep.
2021 Scientific Article in Journal of Proteomics J. Proteomics 230:103981 (2021)
Proteasuria in nephrotic syndrome–quantification and proteomic profiling.
2021 Scientific Article in Brain and behavior Brain Behav. 11:e01928 (2021)
Diabetes type 2 risk gene Dusp8 is associated with altered sucrose reward behavior in mice and humans.
2021 Scientific Article in European Journal of Neuroscience Eur. J. Neurosci. 53, 390-401 (2021)
Loss of the psychiatric risk factor SLC6A15 is associated with increased metabolic functions in primary hippocampal neurons.
2021 Scientific Article in Progress in Biophysics and Molecular Biology Prog. Biophys. Mol. Biol. 159, 86-104 (2021)
Transcriptional signatures regulated by TRPC1/C4-mediated Background Ca2+ entry after pressure-overload induced cardiac remodelling.
2021 Scientific Article in Reproductive Biomedicine Online Reprod. Biomed. Online 42, 217-225 (2021)
Pregnancy outcome in women with polycystic ovary syndrome in relation to second-trimester testosterone levels.
2021 Scientific Article in Fortschritte auf dem Gebiet der Röntgenstrahlen und der Bildgebenden Verfahren Rofo-Fortschr. Rontg. 193, 33-41 (2021)
Magnetic resonance imaging of diverticular disease and its association with adipose tissue compartments and constitutional risk factors in subjects from a western general population.
2021 Scientific Article in International Journal of Radiation Oncology, Biology, Physics Int. J. Radiat. Oncol. Biol. Phys. 109, 76-83 (2021)
Normal tissue response of combined temporal and spatial fractionation in proton minibeam radiation therapy.
2021 Scientific Article in Developmental psychobiology Dev. Psychobiol. 63, 5-15 (2021)
Tracking evoked responses to auditory and visual stimuli in fetuses exposed to maternal high-risk conditions.
2021 Review in NMR in Biomedicine NMR Biomed.:e4266 (2021)
Proton magnetic resonance spectroscopy in skeletal muscle: Experts' consensus recommendations.
2021 Scientific Article in Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet. 129, 750-756 (2021)
Carotid intima-media thickness is a predictor of subclinical myocardial damage in men with type 2 diabetes mellitus.
München, Technische Universität, Fakultät für Medizin, Diss., 2020, 154 S.
Myeloid cells require the ribonuclease Regnase-3 for immune homeostasis and balanced interferon responses in vivo.
2020 Editorial in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 15, 443-446 (2020)
Epigenetic mechanisms in patients with obesity: Fine-tuning of gene activity through DNA-methylation Bertram-Award 2020-a brief overview by the Award Winner Yvonne Boettcher.
2020Vortrag: ASCB/EMBO Cell Bio Vitrual, 07.-12.12.2020, online. (2020)
Endosomal sorting complex protein Vps37a regulates hepatic glucose production via regulating glucagon receptor trafficking.
2020 Frontiers in Psychology Front. Psychol. 11:612441 (2020)
Corrigendum: Core neuropsychological measures for obesity and diabetes trials: Initial report (Front. Psychol, (2020), 11, (554127), 10.3389/fpsyg.2020.554127).
2020 Editorial in Diabetologie, Die Diabetologie 16, 627-629 (2020)
Neues aus der Diabetesforschung.
2020 Meeting abstract in Diabetologia Diabetologia 63, 1, S181-S181 (2020)
Optimal ages for screening for type 1 diabetes risk in children.
2020 Editorial in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 15, 366-366 (2020)
Do NASH-biomarkers follow weight loss in dual GIP-GLP-1-inhibition? Comment.
2020 Meeting abstract in Diabetologia Diabetologia 63, 1, S254-S255 (2020)
Comparison between in vitro differentiation of pancreatic and subcutaneous adipocytes of subjects with normal glucose tolerance.
2020 Meeting abstract in Diabetologia Diabetologia 63, 1, S14-S14 (2020)
Brain insulin sensitivity is modulated by menstrual cycle.
2020 Meeting abstract in Diabetologia Diabetologia 63, 1, S21-S22 (2020)
Oncostatin M inhibits browning of white adipose tissue via gp130 signalling.
2020 Meeting abstract in Diabetologia Diabetologia 63, 1, S384-S385 (2020)
Urinary cathepsin levels are predictive of the improvement of albuminuria and are associated with elevated excretion of free glucosepane.
2020 Meeting abstract in Diabetologia Diabetologia 63, 1, S157-S157 (2020)
Presence of markers associated with viral infections in the pancreas before and after onset of type 1 diabetes.
2020 Meeting abstract in Diabetologia Diabetologia 63, 1, S26-S27 (2020)
Long-term follow-up study of type 1 diabetes patients previously treated with IMCY-0098 or placebo in young adults with recent-onset type 1 diabetes.
2020 Meeting abstract in Diabetologia Diabetologia 63, 1, S101-S102 (2020)
Visualising heterogeneous islet autoantibody trajectories of children who develope type 1 diabetes from multi-site birth cohort studies.
2020 Meeting abstract in Diabetologia Diabetologia 63, 1, S159-S159 (2020)
A visual analytics method to explore the evolution of autoantibodies during progression to type 1 diabetes in multi-site birth cohort studies.
2020 Meeting abstract in Diabetologia Diabetologia 63, 1, S160-S160 (2020)
Heterogeneous islet autoantibody evolution trajectories in multi-site birth cohort studies.
2020 Meeting abstract in Diabetologia Diabetologia 63, 1, S211-S212 (2020)
Maternal mental state correlates with maternal insulin sensitivity and interleukin-6 levels in late pregnancy.
2020 Meeting abstract in Diabetologia Diabetologia 63, 1, S13-S14 (2020)
Empagliflozin improves insulin sensitivity of the hypothalamus in humans with prediabetes.
2020 Meeting abstract in Diabetologia Diabetologia 63, 1, S36-S37 (2020)
Evaluation of determinants of hepatic insulin clearance: a Mendelian randomisation study.
2020 Meeting abstract in Diabetologia Diabetologia 63, 1, S98-S98 (2020)
Exercise changes neuronal processing of food cues in sedentary overweight and obese adults.
2020 Meeting abstract in Diabetologia Diabetologia 63, 1, S182-S183 (2020)
Lrh1/nr5a2 conveys the anti-diabetic effects of the agonist bl001 and promotes alpha-to-beta-cell conversion in streptozotocin-treated mice.
2020 Meeting abstract in Diabetologia Diabetologia 63, 1, S258-S258 (2020)
Postprandial thermogenesis is reduced in obesity.
2020 Editorial in Journal of Neuroendocrinology J. Neuroendocrinol. 32:e12927 (2020)
Neuroendocrinology and brain imaging.
2020 Scientific Article in Eating and Weight Disorders Eat Weight Disord., DOI: 10.1007/s40519-020-01071-7 (2020)
Body appreciation and appearance evaluation in individuals with obesity compared to individuals with normal-weight: findings from a representative German population sample.
2020 Scientific Article in Obesity Obesity 28, 2266-2267 (2020)
Effects of exercise on ACE2.
2020 Scientific Article in Laryngoscope, The Laryngoscope, DOI: 10.1002/lary.29300 (2020)
Fibrin gel suspended autologous chondrocytes as cell-based material for long-term injection laryngoplasty.
2020 Scientific Article in International Journal of Molecular Sciences Int. J. Mol. Sci. 21:9647 (2020)
Intergenerational metabolomic analysis of mothers with a history of gestational diabetes mellitus and their offspring.
2020 Scientific Article in Frontiers in Immunology Front. Immunol. 11:574046 (2020)
Tribbles-1 expression and its function to control inflammatory cytokines, including interleukin-8 levels are regulated by miRNAs in macrophages and prostate cancer cells.
2020 Scientific Article in Nature metabolism Nat. Metab. 2, 1021-1024 (2020)
Autoantibody-negative insulin-dependent diabetes mellitus after SARS-CoV-2 infection: A case report.
2020 Molecular Metabolism Mol. Metab. 41:101068 (2020)
Molecular regulation of urea cycle function by the liver glucocorticoid receptor (vol 4, pg 732, 2015).
2020 Scientific Article in Redox Biology Redox Biol. 37:101723 (2020)
Elevated 4-hydroxynonenal induces hyperglycaemia via Aldh3a1 loss in zebrafish and associates with diabetes progression in humans.
2020 Scientific Article in Sleep Sleep 44:zsaa290 (2020)
How do children with autism spectrum disorder form gist memory during sleep? - A study of slow oscillation-spindle coupling.
2020 Scientific Article in Circulation Genomic and precision medicine Circ. Genom. Precis. Med. 13, 640-648 (2020)
Genetic predisposition to coronary artery disease in type 2 diabetes mellitus.
2020 Scientific Article in Scientific Reports Sci. Rep. 10:22396 (2020)
Dapagliflozin effects on haematocrit, red blood cell count and reticulocytes in insulin-treated patients with type 2 diabetes.
2020 Scientific Article in Frontiers in Immunology Front. Immunol. 11:606338 (2020)
Specific induction of double negative B cells during protective and pathogenic immune responses.
2020 Scientific Article in Scientific Reports Sci. Rep. 10:22453 (2020)
Reduced insulin clearance is linked to subclinical atherosclerosis in individuals at risk for type 2 diabetes mellitus.
2020 Scientific Article in Genome Medicine Genome Med. 12:109 (2020)
Whole blood co-expression modules associate with metabolic traits and type 2 diabetes: An IMI-DIRECT study.
2020 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 106, e34-e44 (2020)
Adolescent nonalcoholic fatty liver disease and type 2 diabetes in young adulthood.
2020 Other: Opinion in Kidney International Kidney Int. 98, 1393-1395 (2020)
Kidney-derived PCSK9-a new driver of hyperlipidemia in nephrotic syndrome?
2020 Scientific Article in eLife eLife 9:e56914 (2020)
Islet vascularization is regulated by primary endothelial cilia via VEGF-A-dependent signaling.
2020 Scientific Article in Kidney & Blood Pressure Research Kidney Blood Press. Res. 45, 955-968 (2020)
Overhydration measured by bioimpedance spectroscopy and urinary serine protease activity are risk factors for progression of chronic kidney disease.
2020 Scientific Article in iScience iScience 23:101763 (2020)
Regulation of guconeogenesis by aldo-keto-reductase 1a1b in zebrafish.
2020 Scientific Article in Genome Biology Genome Biol. 21:299 (2020)
Intronic tRNAs of mitochondrial origin regulate constitutive and alternative splicing.
2020 Scientific Article in Scientific Reports Sci. Rep. 10:20466 (2020)
No modulation of postprandial metabolism by transcutaneous auricular vagus nerve stimulation: A cross-over study in 15 healthy men.
2020 Scientific Article in Genome Medicine Genome Med. 12:97 (2020)
DNA methylation signature in blood mirrors successful weight-loss during lifestyle interventions: The CENTRAL trial.
2020 Scientific Article in Journal of Translational Medicine J. Transl. Med. 18:468 (2020)
Can harmonisation of outcomes bridge the translation gap for pre-clinical research? A systematic review of outcomes measured in mouse models of type 2 diabetes.
2020 Scientific Article in Nutrients Nutrients 12:3254 (2020)
Efficacy and safety of the combination of superoxide dismutase, alpha lipoic acid, Vitamin B12, and carnitine for 12 months in patients with diabetic neuropathy.
2020 Scientific Article in Metabolites Metabolites 10:472 (2020)
Mouse age matters: How age affects the murine plasma metabolome.
2020 Scientific Article in Xenotransplantation Xenotransplantation, DOI: 10.1111/xen.12664 (2020)
Growth hormone receptor knockout to reduce the size of donor pigs for preclinical xenotransplantation studies.
2020 Scientific Article in Kidney international reports Kidney Int. Rep. 5, 2114-2118 (2020)
Acute kidney allograft injury following vitamin C administration for septic shock.
2020 Review in Diabetes Therapy Diabetes Ther. 11, 2465-2476 (2020)
Insights from VERIFY: Early combination therapy provides better glycaemic durability than a stepwise approach in newly diagnosed type 2 diabetes.
2020 Scientific Article in BMJ Open Diabetes Research & Care BMJ Open Diab. Res. Care 8:e001741 (2020)
Insulin sensitivity predicts cognitive decline in individuals with prediabetes.
2020 Scientific Article in Biomedicines Biomedicines 8:507 (2020)
Increased expressions of matrix metalloproteinases (MMPs) in prostate cancer tissues of men with type 2 diabetes.
2020 Scientific Article in International Journal of Obesity Int. J. Obes. 45, 565–576 (2020)
Reduced lipolysis in lipoma phenocopies lipid accumulation in obesity.
2020 Scientific Article in PLoS ONE PLoS ONE 15:e0237799 (2020)
Overweight/obesity as the potentially most important lifestyle factor associated with signs of pneumonia in COVID-19.
2020 Scientific Article in Developmental Cognitive Neuroscience Dev. Cogn. Neurosci . 46:100871 (2020)
Magnetoencephalographic signatures of hierarchical rule learning in newborns.
2020 Scientific Article in Frontiers in Psychology Front. Psychol. 11:554127 (2020)
Core neuropsychological measures for obesity and diabetes trials: Initial report.
2020 Scientific Article in Frontiers in Neuroscience Front. Neurosci. 14:570744 (2020)
Diabetic polyneuropathy is associated with pathomorphological changes in human dorsal root ganglia: A study using 3T MR neurography.
2020 Review in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 15, S101-S111 (2020)
Gestationsdiabetes mellitus (GDM), Diagnostik, Therapie und Nachsorge – Praxisempfehlung – Kurzfassung der S3-Leitlinie (AWMF-Registernummer: 057-008).
2020 Review in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 15, S160-S165 (2020)
Lipidtherapie bei Patienten mit Diabetes mellitus – Eine gemeinsame Stellungnahme der Kommission Fettstoffwechsel sowie der AG Herz und Diabetes der Deutschen Diabetes Gesellschaft (DDG), der Sektion Diabetologie und Stoffwechsel der Deutschen Gesellschaft für Endokrinologie (DGE), der AG Herz und Diabetes der Deutschen Gesellschaft für Kardiologie (DGK) und der gemeinsamen AG Herz – Hormone – Diabetes der DGK, DGE und DDG.
2020 Review in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 15, S166-S169 (2020)
Diabetes mellitus and heart.
2020 Review in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 15, S156-S159 (2020)
Diabetes und Fettleber.
2020 Scientific Article in Nature Nature 588, 151–156 (2020)
Inhibition of LTβR signalling activates WNT-induced regeneration in lung.
2020 Scientific Article in Journal of Neuroendocrinology J. Neuroendocrinol. 32:e12907 (2020)
Investigating obesity-associated brain inflammation using quantitative water content mapping.
2020 Scientific Article in Science Advances Sci. Adv. 6:eabc5586 (2020)
The healthy exocrine pancreas contains preproinsulin-specific CD8 T cells that attack islets in type 1 diabetes.
2020 Scientific Article in Frontiers in Immunology Front. Immunol. 11:564921 (2020)
Glutamic acid decarboxylase injection into lymph nodes: Beta cell function and immune responses in recent onset type 1 diabetes patients.
2020 Scientific Article in Medicine Medicine (Baltimore) 99:e22381 (2020)
Long-term effects of a food pattern on cardiovascular risk factors and age-related changes of muscular and cognitive function.
2020 Scientific Article in Science of the Total Environment, The Sci. Total Environ. 748:142458 (2020)
Accumulation of distinct persistent organic pollutants is associated with adipose tissue inflammation.
2020 Scientific Article in Clinical Chemistry and Laboratory Medicine Clin. Chem. Lab. Med. 59, 913-920 (2020)
Evaluation of the first immunosuppressive drug assay available on a fully automated LC-MS/MS-based clinical analyzer suggests a new era in laboratory medicine.
2020 Review in Antioxidants Antioxidants 9:939 (2020)
The glyoxalase system—new insights into an ancient metabolism.
2020 Scientific Article in Journal of Hepatology J. Hepatol. 73, 1347-1359 (2020)
Reduced mitochondrial resilience enables non-canonical induction of apoptosis after TNF receptor signaling in virus-infected hepatocytes.
2020 Scientific Article in Cell Communication and Signaling Cell Commun. Signal. 18:155 (2020)
Thrombospondin-1/CD47 signaling modulates transmembrane cation conductance, survival, and deformability of human red blood cells.
2020 Scientific Article in Journal of Cachexia, Sarcopenia and Muscle J. Cachexia Sarcopenia Muscle 11, 1459-1475 (2020)
High levels of modified ceramides are a defining feature of murine and human cancer cachexia.
2020 Scientific Article in PLoS ONE PLoS ONE 15:e0238533 (2020)
Molecular classification of the placebo effect in nausea.
2020 Scientific Article in Advanced materials Adv. Mater. 32:e2003913 (2020)
Prediction of chronic inflammation for inhaled particles: The impact of material cycling and quarantining in the lung epithelium.
2020 Scientific Article in Scientific Reports Sci. Rep. 10:18334 (2020)
Increased estrogen to androgen ratio enhances immunoglobulin levels and impairs B cell function in male mice.
2020 Scientific Article in Frontiers in cell and developmental biology Front. Cell Dev. Biol. 8:587778 (2020)
Dose-dependent and subset-specific regulation of midbrain dopaminergic neuron differentiation by LEF1-mediated WNT1/b-catenin signaling.
2020 Scientific Article in iScience iScience 23:101516 (2020)
Progressive proteome changes in the myocardium of a pig model for Duchenne. muscular dystrophy.
2020 Scientific Article in Communications Biology Comm. Biol. 3:628 (2020)
PAX6 mutation alters circadian rhythm and beta cell function in mice without affecting glucose tolerance.
2020 Scientific Article in Molecular Nutrition and Food Research Mol. Nutr. Food Res. 64:e2000419 (2020)
Dietary rapeseed oil supplementation reduces hepatic steatosis in obese men-a randomized controlled trial.
2020 Scientific Article in Cancer Research Cancer Res. 80, 5231-5244 (2020)
Phosphorylation control of p53 DNA binding cooperativity balances tumorigensis and aging.
2020 Scientific Article in Cell Reports Cell Rep. 33:108295 (2020)
The obesity susceptibility gene TMEM18 promotes adipogenesis through direct activation of PPARG.
2020 Review in Nature Nature 587, 377–386 (2020)
LifeTime and improving European healthcare through cell-based interceptive medicine.
2020 Scientific Article in Scientific Reports Sci. Rep. 10:16497 (2020)
FFA2-, but not FFA3-agonists inhibit GSIS of human pseudoislets: A comparative study with mouse islets and rat INS-1E cells.
2020 Scientific Article in Science Advances Sci. Adv. 6:eaaz4551 (2020)
METTL6 is a tRNA m3C methyltransferase that regulates pluripotency and tumor cell growth.
2020 Review in Current opinion in pharmacology Curr. Opin. Pharmacol. 53, 101-116 (2020)
Exploiting common aspects of obesity and cancer cachexia for future therapeutic strategies.
2020 Review in Diabetologie, Die Diabetologie 16, 647–653 (2020)
Materner Metabolismus und fetale Entwicklung.
2020 Scientific Article in Molecular Metabolism Mol. Metab. 42:101062 (2020)
Histone deacetylase 5 regulates interleukin 6 secretion and insulin action in skeletal muscle.
2020 Scientific Article in International Journal of Obesity Int. J. Obes. 45, 331-336 (2020)
Circulating cell adhesion molecules in metabolically healthy obesity.
2020 Scientific Article in International Journal of Cancer Int. J. Cancer 147, 3523-3538 (2020)
miR-34a is upregulated in AIP-mutated somatotropinomas and promotes octreotide resistance.
2020 Scientific Article in American Journal of Physiology - Endocrinology and Metabolism Am. J. Physiol. Endocrinol. Metab. 319, E509-E518 (2020)
Nutritional and metabolic regulation of the metabolite dimethylguanidino valeric acid: An early marker of cardiometabolic disease.
2020 Review in Diabetologie, Die Diabetologie 16, 654-661 (2020)
Typ-1-Diabetes: Früherkennung und Ansätze zur Prävention.Update 2020.
2020 Review in Endocrinology and Metabolism Endocrinol. Metab. 35, 487–493 (2020)
Metabolically healthy and unhealthy normal weight and obesity.
2020 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 105:dgaa571 (2020)
Response of mitochondrial respiration in adipose tissue and muscle to 8 weeks of endurance exercise in obese subjects.
2020 Scientific Article in Scientific Reports Sci. Rep. 10:15093 (2020)
Defining diagnostic cutoffs in neurological patients for serum very long chain fatty acids (VLCFA) in genetically confirmed X-Adrenoleukodystrophy.
2020 Review in Diabetologie, Die Diabetologie 16, 560–565 (2020)
Fettleber und Diabetes: Pathomechanismen.
2020 Scientific Article in Nature Communications Nat. Commun. 11, 4031 (2020)
Discovery of EMRE in fungi resolves the true evolutionary history of the mitochondrial calcium uniporter.
2020 Scientific Article in FASEB Journal FASEB J. 34, 12946-12962 (2020)
cAMP-dependent protein kinase inhibits FoxO activity and regulates skeletal muscle plasticity in mice.
2020 Scientific Article in Nature medicine Nat. Med. 26, 1247-1255 (2020)
A combined risk score enhances prediction of type 1 diabetes among susceptible children.
2020 Scientific Article in Physiology & Behavior Physiol. Behav. 226:113071 (2020)
Visual food cues decrease blood glucose and glucoregulatory hormones following an oral glucose tolerance test in normal-weight and obese men.
2020 Scientific Article in Diabetes Diabetes 69, 2756-2765 (2020)
Machine learning approaches reveal metabolic signatures of incident chronic kidney disease in individuals with prediabetes and type 2 diabetes.
2020 Letter to the Editor in Gut (eGut) Gut 70, 1801-1802 (2020)
Blurring the picture in leaky gut research: How shortcomings of zonulin as a biomarker mislead the field of intestinal permeability.
2020 Scientific Article in Genes Genes 11:1174 (2020)
Characterization of hormone-dependent pathways in six human prostate-cancer cell lines: A gene-expression study.
2020 Scientific Article in Royal Society Open Science R. Soc. Open Sci. 7:200701 (2020)
Ectopic fat accumulation in human astrocytes impairs insulin action.
2020 Scientific Article in Diabetes Diabetes 69, 2766-2778 (2020)
Deciphering the plasma proteome of type 2 diabetes.
2020 Scientific Article in Genome Medicine Genome Med. 12:87 (2020)
The aging mouse microbiome has obesogenic characteristics.
2020 Scientific Article in Hormone and Metabolic Research Horm. Metab. Res. 52, 809-814 (2020)
No independent association of circulating fetuin-A with insulin sensitivity in young women.
2020 Other: Opinion in Diabetes Care Diabetes Care 43, E134-E136 (2020)
Increased hepatic ACE2 expression in NAFL and diabetes-A risk for COVID-19 patients?
2020 Scientific Article in European Journal of Endocrinology Eur. J. Endocrinol. 183, 233-244 (2020)
Pro-neurotensin depends on renal function and is related to all-cause mortality in chronic kidney disease.
2020 Other: Opinion in Cell Metabolism Cell Metab. 32, 512-513 (2020)
Mitochondrial ejection for cardiac protection: The Macrophage Connection.
2020 Scientific Article in Human Brain Mapping Hum. Brain Mapp. 41, 3839-3854 (2020)
Can we predict real-time fMRI neurofeedback learning success from pretraining brain activity?
2020 Scientific Article in Journal of Hepatology J. Hepatol. 73, 771-782 (2020)
Immunity-related GTPase induces lipophagy to prevent excess hepatic lipid accumulation.
2020 Scientific Article in Stem Cell Research Stem Cell Res. 47:101927 (2020)
Generation of a human iPSC line harboring a biallelic large deletion at the INK4 locus (HMGUi001-A-5).
2020 Review in Lancet Diabetes and Endocrinology Lancet Diabet. Endocrinol. 8, 616-627 (2020)
Causes, consequences, and treatment of metabolically unhealthy fat distribution.
2020 Scientific Article in EMBO Journal, The EMBO J. 39:e105696 (2020)
MiT/TFE factors control ER-phagy via transcriptional regulation of FAM134B.
2020 Scientific Article in Nutrients Nutrients 12:2124 (2020)
Compound 18 improves glucose tolerance in a hepatocyte TGR5-dependent manner in mice.
2020 Scientific Article in Annals of Internal Medicine Ann. Intern. Med. 172, 836-837 (2020)
Lipodystrophic nonalcoholic fatty liver disease induced by immune checkpoint blockade.
2020 Scientific Article in Diabetes, Obesity and Metabolism Diabetes Obes. Metab. 22, 2151-2160 (2020)
Benefit/risk profile of dapagliflozin 5 mg in theDEPICT-1 and-2 trials in individuals with type 1 diabetes and body mass index >= 27 kg/m(2).
2020 Other: Opinion in Diabetes Diabetes 69, 1605-1607 (2020)
A new FGF21 analog for the treatment of fatty liver disease.
2020 Scientific Article in Metabolism: clinical and experimental Metabolism 110:154303 (2020)
Early adaptive thermogenesis is a determinant of weight loss after six weeks of caloric restriction in overweight subjects.
2020 Scientific Article in Nutrients Nutrients 12:2064 (2020)
Normalized indices derived from visceral adipose mass assessed by magnetic resonance imaging and their correlation with markers for insulin resistance and prediabetes.
2020 Scientific Article in PLoS ONE PLoS ONE 15:e0235310 (2020)
A pilot study: Auditory steady-state responses (ASSR) can be measured in human fetuses using fetal magnetoencephalography (fMEG).
2020 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 105:dgaa435 (2020)
Pancreatic steatosis associates with impaired insulin secretion in genetically predisposed individuals.
2020 Scientific Article in Journal of Personalized Medicine J. Pers. Med. 10:E124 (2020)
Transcript levels of aldo-keto reductase family 1 subfamily C (AKR1C) are increased in prostate tissue of patients with type 2 diabetes.
2020 Scientific Article in Mechanisms of Ageing and Development Mech. Ageing Dev. 190:111307 (2020)
Age-dependent membrane release and degradation of full-length glycosylphosphatidylinositol-anchored proteins in rats.
2020 Scientific Article in Cell Reports Cell Rep. 32:108059 (2020)
Mitochondrial regulation of the 26S proteasome.
2020 Scientific Article in Liver International Liver Int. 40, 2982-2997 (2020)
High-protein diet more effectively reduces hepatic fat than low-protein diet despite lower autophagy and FGF21 levels.
2020 Scientific Article in Scientific Reports Sci. Rep. 10:14321 (2020)
Association of generalized and central obesity with serum and salivary cortisol secretion patterns in the elderly: Findings from the cross sectional KORA-Age study.
2020 Scientific Article in Scientific Reports Sci. Rep. 10:14461 (2020)
Light sheet fluorescence microscopy guided MALDI-imaging mass spectrometry of cleared tissue samples.
2020 Scientific Article in PLoS ONE PLoS ONE 15:e0237364 (2020)
Serum uromodulin is inversely associated with arterial hypertension and the vasoconstrictive prohormone CT-proET-1 in the population-based KORA F4 study.
2020 Scientific Article in Journal of Clinical Investigation J. Clin. Invest. 130, 6093-6108 (2020)
Type 2 diabetes risk gene Dusp8 regulates hypothalamic Jnk signaling and insulin sensitivity.
2020 Review in Biochemical Journal / Reviews Biochem. J. 477, 2509-2541 (2020)
Identification and characterization of adipose surface epitopes.
2020 Other: Opinion in Cell Metabolism Cell Metab. 32, 331-333 (2020)
An antibody attack against body wasting in cancer.
2020 Other: Opinion in Nature metabolism Nat. Metab., DOI: 10.1038/s42255-020-0263-0 (2020)
Career pathways, part 2.
2020 Scientific Article in Scientific Reports Sci. Rep. 10:12407 (2020)
Increased mitochondrial respiration of adipocytes from metabolically unhealthy obese compared to healthy obese individuals.
2020 Review in International Journal of Molecular Sciences Int. J. Mol. Sci. 21:4688 (2020)
Vascular homeostasis and inflammation in health and disease-lessons from single cell technologies.
2020 Scientific Article in Diabetes Care Diabetes Care 43, 2066-2073 (2020)
Hierarchical order of distinct autoantibody spreading and progression to type 1 diabetes in the Teddy study.
2020 Scientific Article in Cancers Cancers 12:1814 (2020)
Human prostate cancer is characterized by an increase in urea cycle metabolites.
2020 Scientific Article in Nature Communications Nat. Commun. 11:3555 (2020)
Vagus nerve stimulation boosts the drive to work for rewards.
2020 Scientific Article in Molecular Metabolism Mol. Metab. 40:101026 (2020)
STAT5 is required for lipid breakdown and beta-adrenergic responsiveness of brown adipose tissue.
2020Vortrag: Virtueller Kongress ADA, 12-16 June 2020, Virtuell. (2020)
GLP-1 hypersecretion in gestational diabetes.
2020Vortrag: Virtueller Kongress ADA, 12.-16 June 2020, Virtuell. (2020)
Detection of diabetes from whole-body magnetic resonance imaging using deep learning.
2020 Editorial in Mammalian Genome Mamm. Genome, DOI: 10.1007/s00335-020-09843-3 (2020)
Introduction to mammalian genome special issue: Epigenetics.
2020 Scientific Article in Neuroscience Letters Neurosci. Lett. 735:135206 (2020)
Physiological relevance of the neuronal isoform of inositol-1,4,5-trisphosphate 3-kinases in mice.
2020 Scientific Article in Cells Cells 9:1508 (2020)
Higher mast cell accumulation in human adipose tissues defines clinically favorable obesity sub-phenotypes.
2020 Scientific Article in Scientific Reports Sci. Rep. 10:10240 (2020)
Distinct abdominal and gluteal adipose tissue transcriptome signatures are altered by exercise training in African women with obesity.
2020 Scientific Article in Hormone and Metabolic Research Horm. Metab. Res. 52, 877-881 (2020)
Nicotinamide nucleotide transhydrogenase (Nnt) is related to obesity in mice.
2020 Scientific Article in Journal of Clinical Investigation J. Clin. Invest. 130, 4094-4103 (2020)
Neuroimaging of hypothalamic mechanisms related to glucose metabolism in anorexia nervosa and obesity.
2020 Scientific Article in Obesity Obesity 28, 1456-1466 (2020)
Exercise training alters red blood cell fatty acid desaturase indices and adipose tissue fatty acid profile in African women with obesity.
2020 Scientific Article in Journal of Molecular Medicine J. Mol. Med. 98, 1139–1148 (2020)
Genetically programmed changes in transcription of the novel progranulin regulator.
2020 Review in Molecular Metabolism Mol. Metab. 39:101044 (2020)
Diabetes, infection risk and COVID-19.
2020 Scientific Article in Biomedicines Biomedicines 8:184 (2020)
The Fabp4-Cre-model is insufficient to study Hoxc9 function in adipose tissue.
2020 Scientific Article in Nucleic Acids Research Nucleic Acids Res. 48, 8393-8407 (2020)
Anti-inflammatory functions of the glucocorticoid receptor require DNA binding.
2020 Scientific Article in Molecular Metabolism Mol. Metab. 40:101029 (2020)
Lack of Gαi2 proteins in adipocytes attenuates diet-induced obesity.
2020 Scientific Article in NMR in Biomedicine NMR Biomed.:e4358 (2020)
Feasibility of precise and reliable glucose quantification in human whole blood samples by 1 tesla benchtop NMR.
2020 Review in Ophthalmologe, Der Ophthalmologe 117, 631-637 (2020)
Seroprävalenz und SARS-CoV-2-Testung in Gesundheitsberufen.
2020 Review in Computational and Structural Biotechnology Journal Comp. Struc. Biotech. J. 18, 1330-1341 (2020)
Seq-ing answers: Current data integration approaches to uncover mechanisms of transcriptional regulation.
2020 Scientific Article in Stem Cell Research Stem Cell Res. 46:101874 (2020)
Generation of a homozygous ARX nuclear CFP (ARX(nCFP/nCFP)) reporter human iPSC line (HMGUi001-A-4).
2020 Review in Advanced Drug Delivery Reviews Adv. Drug Deliv. Rev. 159, 34-53 (2020)
Insights into incretin-based therapies for treatment of diabetic dyslipidemia.
2020 Scientific Article in Acta Neuropathologica Acta Neuropathol. 140, 121–142 (2020)
Congenic expression of poly-GA but not poly-PR in mice triggers selective neuron loss and interferon responses found in C9orf72 ALS.
2020 Scientific Article in Journal of Diabetes and its Complications J. Diab. Complic. 34:107648 (2020)
Urinary cathepsin L is predictive of changes in albuminuria and correlates with glucosepane in patients with type 2 diabetes in a closed-cohort study.
2020 Scientific Article in PLoS ONE PLoS ONE 15:e0230162 (2020)
The occurrence of tarsal injuries in male mice of C57BL/6N substrains in multiple international mouse facilities.
2020 Scientific Article in Particle and Fibre Toxicology Part. Fibre Toxicol. 17:27 (2020)
Influence of wood species on toxicity of log-wood stove combustion aerosols: A parallel animal and air-liquid interface cell exposure study on spruce and pine smoke.
2020 Review in Mammalian Genome Mamm. Genome 31, 146–156 (2020)
Genetic control of non-genetic inheritance in mammals: state-of-the-art and perspectives.
2020 Scientific Article in Neurobiology of Learning and Memory Neurobiol. Learn. Mem. 173:107245 (2020)
Deepened sleep makes hippocampal spatial memory more persistent.
2020 Scientific Article in Immunity, Inflammation and Disease Immun. Inflamm. Dis. 8, 299-309 (2020)
Geographic location determines beta-cell autoimmunity among adult Ghanaians: Findings from the RODAM study.
2020 Scientific Article in International Journal of Pharmaceutics Int. J. Pharm. 16, 310-318 (2020)
Adenium obesum flowers extract mitigates testicular injury and oxidative stress in streptozotocin-induced diabetic rats.
2020 Scientific Article in BMJ Open Diabetes Research & Care BMJ Open Diab. Res. Care 8:e001425 (2020)
Proinsulin to insulin ratio is associated with incident type 2 diabetes but not with vascular complications in the KORA F4/FF4 study.
2020 Scientific Article in Nutrients Nutrients 12:1619 (2020)
Circulating and adipose tissue fatty acid composition in black South African women with obesity: A cross-sectional study.
2020 Scientific Article in Environmental Science and Pollution Research Environ. Sci. Pollut. Res. 27, 30118-30132 (2020)
Farnesol attenuates oxidative stress and liver injury and modulates fatty acid synthase and acetyl-CoA carboxylase in high cholesterol-fed rats.
2020 Scientific Article in Nutrients Nutrients 12:1527 (2020)
Vertebral bone marrow fat is independently associated to vat but not to sat: Kora FF4—whole-body mr imaging in a population-based cohort.
2020 Scientific Article in American Journal of Physiology - Endocrinology and Metabolism Am. J. Physiol. Endocrinol. Metab. 318, E701-E709 (2020)
Identification and regulation of the xenometabolite derivatives cis- and trans-3,4-methylene-heptanoylcarnitine in plasma and skeletal muscle of exercising humans.
2020 Review in Seminars in cell & developmental biology Semin. Cell Dev. Biol. 108, 72-81 (2020)
Hepatic lipid droplet homeostasis and fatty liver disease.
2020 Letter to the Editor in Diabetologia Diabetologia, DOI: 10.1007/s00125-020-05175-8 (2020)
Why is the presence of autoantibodies against GAD associated with a relatively slow progression to clinical diabetes?
2020 Review in Diabetologie, Die Diabetologie 16, 362-372 (2020)
Gestational diabetes mellitus (GDM), diagnostics, therapy and aftercare: Practice Recommendation—Abstract of the S3 Guideline (AWMF Register Number: 057-008).
2020 Review in Deutsche Medizinische Wochenschrift - DMW Dtsch. Med. Wochenschr. 145, 601-608 (2020)
Pathologisch-genetisch orientierte Diabetes-Reklassifizierung.
2020 Review in Lancet Diabetes and Endocrinology Lancet Diabet. Endocrinol. 8, 524-534 (2020)
Central nervous pathways of insulin action in the control of metabolism and food intake.
2020 Scientific Article in Scientific Reports Sci. Rep. 10:7593 (2020)
Characterization of experimental diabetic neuropathy using multicontrast magnetic resonance neurography at ultra high field strength.
2020 Scientific Article in Acta Physiologica Acta Physiol. 231:e13512 (2020)
Plasminogen deficiency does not prevent sodium retention in a genetic mouse model of experimental nephrotic syndrome.
2020 Scientific Article in Nature Nature 581, 310-315 (2020)
Statin therapy is associated with lower prevalence of gut microbiota dysbiosis.
2020 Scientific Article in Molecules Molecules 25:1992 (2020)
Membrane phospholipids and polyphosphates as cofactors and binding molecules of SERPINA12 (Vaspin).
2020 Scientific Article in Endocrinology, Diabetes & Metabolism Case Reports Endocrinol. Diabetes Metab. Case Rep. 3, e00136 (2020)
Brain substrate metabolism and ß-cell function in humans: A positron emission tomography study.
2020 Other: Opinion in Trends in Pharmacological Sciences Trends Pharmacol. Sci. 41, 384-386 (2020)
Pharmacological targeting of the actin cytoskeleton to drive endocrinogenesis.
2020 Scientific Article in Cytokine Cytokine 131:155088 (2020)
Adipocytokines are not associated with gestational diabetes mellitus but with pregnancy status.
2020 Scientific Article in Metabolism: clinical and experimental Metabolism 107:154219 (2020)
Altered metabolic and hormonal responses to moderate exercise in overweight/obesity.
2020 Review in Diabetes & Metabolism Journal Diabetes Metab. J. 44, 509-528 (2020)
Consequences of obesity on the sense of taste: Taste buds as treatment targets?
2020 Scientific Article in Molecular Metabolism Mol. Metab. 36:100953 (2020)
De novo discovery of metabolic heterogeneity with immunophenotype-guided imaging mass spectrometry.
2020 Review in Current opinion in pharmacology Curr. Opin. Pharmacol. 53, 35-44 (2020)
Anti-inflammatory glucocorticoid action: Genomic insights and emerging concepts.
2020 Review in Lancet Diabetes and Endocrinology Lancet Diabet. Endocrinol. 8, 546-550 (2020)
Practical recommendations for the management of diabetes in patients with COVID-19.
2020 Scientific Article in Molecular Metabolism Mol. Metab. 35:100949 (2020)
ApoA-1 improves glucose tolerance by increasing glucose uptake into heart and skeletal muscle independently of AMPKα2.
2020 Scientific Article in Acta Physiologica Acta Physiol. 230:e13496 (2020)
Exercise-dependent increases in protein synthesis are accompanied by chromatin modifications and increased MRTF-SRF signalling.
2020 Review in Cell Cell 181, 1189-1193 (2020)
Biomedical research goes viral: Dangers and opportunities.
2020 Scientific Article in BMC nephrology BMC Nephrol. 21:178 (2020)
Low-dose alemtuzumab induction in a tailored immunosuppression protocol for sensitized kidney transplant recipients.
2020 Review in Internist, Der Internist 61, 759-765 (2020)
New pharmacological treatment options for nonalcoholic fatty liver disease.
2020 Scientific Article in Nature Communications Nat. Commun. 11:2306 (2020)
The scaffold protein p62 regulates adaptive thermogenesis through ATF2 nuclear target activation.
2020 Scientific Article in Stem Cell Research Stem Cell Res. 45:101797 (2020)
Generation of an INSULIN-H2B-Cherry reporter human iPSC line.
2020 Other: Opinion in Nature Reviews - Endocrinology Nat. Rev. Endocrinol. 16, 341–342 (2020)
Obesity and impaired metabolic health in patients with COVID-19.
2020 Scientific Article in Journal of Medicinal Chemistry J. Med. Chem. 63, 5723-5733 (2020)
Structural studies on the inhibitory binding mode of aromatic coumarinic esters to human kallikrein-related peptidase 7.
2020 Nature metabolism Nat. Metab. 2, 380 (2020)
Author Correction: Targeted pharmacological therapy restores β-cell function for diabetes remission (Nature Metabolism, (2020), 2, 2, (192-209), 10.1038/s42255-020-0171-3).
2020 Scientific Article in Nature Biotechnology Nat. Biotechnol. 38, 1061–1072 (2020)
Generation of pancreatic β cells from CD177+ anterior definitive endoderm.
2020 Scientific Article in Journal of Neuroscience Methods J. Neurosci. Methods 339:108744 (2020)
Establishing sample-preparation protocols for X-ray phase-contrast CT of rodent spinal cords: Aldehyde fixations and osmium impregnation.
2020 Scientific Article in Physiology & Behavior Physiol. Behav. 219:112861 (2020)
Subliminal fatty acid-induced gut-brain signals attenuate sensitivity to exteroceptive rewards in food but not in sex or financial domains, in healthy men.
2020 Review in Mammalian Genome Mamm. Genome 31, 119–133 (2020)
Nutrition and its role in epigenetic inheritance of obesity and diabetes across generations.
2020 Scientific Article in EMBO Journal, The EMBO J. 39:e103477 (2020)
Compromised DNA repair is responsible for diabetes-associated fibrosis.
2020 Scientific Article in Clinical EEG and neuroscience Clin. EEG Neurosci. 51, 331-338 (2020)
Studying the effect of maternal pregestational diabetes on fetal neurodevelopment using magnetoencephalography.
2020 Scientific Article in Cell Metabolism Cell Metab. 31, 773-790 (2020)
Circulating triglycerides gate dopamine-associated behaviors through DRD2-expressing neurons.
2020 Scientific Article in Neurochemistry International Neurochem. Int. 136:104713 (2020)
Detection and quantification of the anti-obesity drug celastrol in murine liver and brain.
2020 Scientific Article in Current Biology Curr. Biol. 30, 1142-1151 (2020)
Epithelial planar bipolarity emerges from Notch-mediated asymmetric inhibition of Emx2.
2020 Review in Nutrients Nutrients 12:1153 (2020)
Plausible biological interactions of low- and non-calorie sweeteners with the intestinal microbiota: An update of recent studies.
2020 Meeting abstract in Wound repair and regeneration Wound Repair Regen. 28, A2-A2 (2020)
Beta cell development, heterogeneity and regeneration.
2020 Scientific Article in European Journal of Immunology Eur. J. Immunol. 50, 903-905 (2020)
Soluble IL-7 receptor alpha concentration in cord blood is linked to sex and maternal diabetes, but not with subsequent development of type 1 diabetes.
2020 Scientific Article in Nature Communications Nat. Commun. 11:1841 (2020)
Brain insulin sensitivity is linked to adiposity and body fat distribution.
2020 Scientific Article in Hormone and Metabolic Research Horm. Metab. Res. 52, 685-688 (2020)
COMP-ang-1 improves glucose uptake in db/db mice with type 2 diabetes.
2020 Scientific Article in Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet. 128, 414-422 (2020)
Allan-herndon-dudley-syndrome: Considerations about the brain phenotype with implications for treatment strategies.
2020 Scientific Article in Deutsche Medizinische Wochenschrift - DMW Dtsch. Med. Wochenschr. 145, 423-428 (2020)
Metabolische Chirurgie bei Typ-2-Diabetes?
2020 Scientific Article in EMBO Molecular Medicine EMBO Mol. Med. 12:e09271 (2020)
Endothelial Notch signaling controls insulin transport in muscle.
2020 Scientific Article in Lancet Diabetes and Endocrinology Lancet Diabet. Endocrinol. 8, 301-312 (2020)
Early detection of diabetic kidney disease by urinary proteomics and subsequent intervention with spironolactone to delay progression (PRIORITY): A prospective observational study and embedded randomised placebo-controlled trial.
2020 Scientific Article in Nature medicine Nat. Med. 26, 589–598 (2020)
Effects of underfeeding and oral vancomycin on gut microbiome and nutrient absorption in humans.
2020 Scientific Article in International Journal of Obesity Int. J. Obes. 44, 2124–2136 (2020)
The repertoire of Adhesion G protein-coupled receptors in adipocytes and their functional relevance.
2020 Scientific Article in Scientific Reports Sci. Rep. 10:1487 (2020)
Associations between adipose tissue volume and small molecules in plasma and urine among asymptomatic subjects from the general population.
2020 Review in Endocrine Reviews Endocr. Rev. 41, 405-420:bnaa004 (2020)
Metabolically healthy obesity.
2020 Scientific Article in Diabetes Care Diabetes Care 43, 1085-1093 (2020)
Efficacy and Safety of Liraglutide 3.0 mg in Individuals With Overweight or Obesity and Type 2 Diabetes Treated With Basal Insulin: The SCALE Insulin Randomized Controlled Trial.
2020 Scientific Article in British Journal of Radiology, The Br. J. Radiol. 93, 20190874 (2020)
Measurement of total and visceral fat mass in young adult women: A comparison of MRI with anthropometric measurements with and without bioelectrical impedance analysis.
2020 Scientific Article in Mammalian Genome Mamm. Genome 31, 30-48 (2020)
A comprehensive and comparative phenotypic analysis of the collaborative founder strains identifies new and known phenotypes.
2020 Review in BMJ open sport & exercise medicine BMJ Open Sport Exerc. Med. 6:e000658 (2020)
Spotlight on the fetus: How physical activity during pregnancy influences fetal health: A narrative review.
2020 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 105, e2192–e2206 (2020)
Randomized 52-week phase 2 trial of albiglutide vs placebo in adult patients with newly diagnosed type 1 diabetes.
2020 Scientific Article in Genes and Development Genes Dev. 34, 715-729 (2020)
The rRNA m6A methyltransferase METTL5 is involved in pluripotency and developmental programs.
2020 Scientific Article in Analytica Chimica Acta Anal. Chim. Acta 1105, 120-127 (2020)
Which is the urine sample material of choice for metabolomics-driven biomarker studies?
2020 Review in Diabetologie, Die Diabetologie 16, 215-219 (2020)
Long-term effects of diabetes prevention measures: Are there effects beyond pure diabetes prevention?
2020 Scientific Article in Cell Metabolism Cell Metab. 31, 493-502 (2020)
Short-term consumption of sucralose with, but not without, carbohydrate impairs neural and metabolic sensitivity to sugar in humans.
2020 Editorial in Cell Metabolism Cell Metab. 31, 443-444 (2020)
Gut microbes controlling blood sugar: No fire required!
2020 Other: Opinion in Mammalian Genome Mamm. Genome 31, 49-53 (2020)
PATHBIO: An international training program for precision mouse phenotyping.
2020 Scientific Article in Nature Communications Nat. Commun. 11:655 (2020)
Human and mouse essentiality screens as a resource for disease gene discovery.
2020 Scientific Article in JAMA: Journal of the American Medical Association JAMA 323, 339-351 (2020)
Yield of a public health screening of children for islet autoantibodies in Bavaria, Germany.
2020 Review in Diabetologie, Die Diabetologie 16, 234–238 (2020)
Prädiabetes und Diabetessubphänotypen – Konsequenzen für die Prävention.
2020 Scientific Article in European Radiology Eur. Radiol. 30, 3417-3428 (2020)
Bone marrow fat fraction assessment in regard to physical activity: KORA FF4-3-T MR imaging in a population-based cohort.
2020 Scientific Article in Diabetologia Diabetologia 63, 1236-1247 (2020)
Pharmacological targeting of α3β4 nicotinic receptors improves peripheral insulin sensitivity in mice with diet-induced obesity.
2020 Review in Biological Chemistry Biol. Chem. 401, 1019-1030 (2020)
Proteostasis in thermogenesis and obesity.
2020 Scientific Article in Diabetes Diabetes 69, 465-476 (2020)
Longitudinal metabolome-wide signals prior to the appearance of a first islet autoantibody in children participating in the TEDDY Study.
2020 Review in Zeitschrift für Gastroenterologie Z. Gastroenterol. 58, 160-170 (2020)
Typhus abdominalis und Paratyphus.
2020 Scientific Article in Diabetes Diabetes 69, 713-723 (2020)
Troponin T parallels structural nerve damage in type 2 diabetes: A cross-sectional study using magnetic resonance neurography.
2020 Scientific Article in Scientific Reports Sci. Rep. 10:1457 (2020)
Preparation of single- and double-oligonucleotide antibody conjugates and their application for protein analytics.
2020 Scientific Article in Diabetes Diabetes 69, 915-926 (2020)
DLL1- and DLL4-mediated Notch signaling is essential for adult pancreatic islet homeostasis.
2020 Scientific Article in Translational Psychiatry Transl. Psychiatry 10:66 (2020)
A truncating Aspm allele leads to a complex cognitive phenotype and region-specific reductions in parvalbuminergic neurons.
2020 Scientific Article in Molecules Molecules 25:896 (2020)
CB1 receptor-dependent and independent induction of lipolysis in primary rat adipocytes by the inverse agonist rimonabant (SR141716A).
2020 Meeting abstract in Naunyn-Schmiedeberg's Archives of Pharmacology Naunyn-Schmiedebergs Arch. Pharmakol. 393, 18-19 (2020)
Novel mitochondrial Ca2+ enhancers for the treatment of cardiac arrhythmia.
2020 Scientific Article in American Journal of Physiology - Endocrinology and Metabolism Am. J. Physiol. Endocrinol. Metab. 318, E462-E479 (2020)
Upregulated phospholipase D activity toward glycosylphosphatidylinositol-anchored proteins in micelle-like serum complexes in metabolically deranged rats and humans.
2020 Scientific Article in Molecular Metabolism Mol. Metab. 36:100978 (2020)
Functional changes of the liver in the absence of growth hormone (GH) action - Proteomic and metabolomic insights from a GH receptor deficient pig model.
2020 Scientific Article in Atherosclerosis Atherosclerosis 297, 1-7 (2020)
Serum uromodulin and risk for cardiovascular morbidity and mortality in the community-based KORA F4 study.
2020 Scientific Article in Cells Cells 9:191 (2020)
Cytokine directed chondroblast trans-differentiation: JAK inhibition facilitates direct reprogramming of fibroblasts to chondroblasts.
2020 Review in Genome Biology Genome Biol. 21:18 (2020)
The deep genome project.
In: Beyond Our Genes. 2020. 159-173
Introduction to epigenetic inheritance: Definition, mechanisms, implications and relevance.
In: Beyond Our Genes. 2020. 175-208
The (not so) controversial role of DNA methylation in epigenetic inheritance across generations.
In: Beyond Our Genes. 2020. 231-259
Future perspectives in epigenetic inheritance.
2020 Scientific Article in Cell Reports Cell Rep. 30, 3183-3194.e4 (2020)
iTAG-RNA isolates cell-specific transcriptional responses to environmental stimuli and identifies an RNA-based endocrine axis.
2020 Scientific Article in Investigative Ophthalmology & Visual Science, IOVS Invest. Ophthalmol. Vis. Sci. 61:44 (2020)
Mutation in Bmpr1b leads to optic disc coloboma and ventral retinal gliosis in mice.
2020 Scientific Article in PLoS Genetics PLoS Genet. 16:e1008577 (2020)
High-throughput discovery of genetic determinants of circadian misalignment.
Springer International Publishing, 2020.:doi.org/10.1007/978-3-030-35213-
Pathophyiology of gene and environment interaction and epigenetic inheritance.
2020 Scientific Article in Acta Diabetologica Acta Diabetol. 57, 495-498 (2020)
Tamoxifen treatment causes early hepatic insulin resistance.
2020 Scientific Article in FASEB Journal FASEB J. 34, 3336-3346 (2020)
Robo4-mediated pancreatic endothelial integrity decreases inflammation and islet destruction in autoimmune diabetes.
2020 Scientific Article in Diabetes Care Diabetes Care 43, 556-562 (2020)
Distinct growth phases in early life associated with the risk of type 1 diabetes: The TEDDY study.
2020 Scientific Article in Diabetes Diabetes 69, 661-669 (2020)
Maternal type 1 diabetes reduces autoantigen-responsive CD4(+) T cells in Offspring.
2020 Scientific Article in Diabetes, Obesity and Metabolism Diabetes Obes. Metab. 22, 759-766 (2020)
Effectiveness and safety of insulin glargine 300 U/mL in insulin-naive patients with type 2 diabetes after failure of oral therapy in a real-world setting.
2020 Scientific Article in Blood Cancer Journal Blood Cancer J. 10:2 (2020)
Comparison of three different serum-free light-chain assays-implications on diagnostic and therapeutic monitoring of multiple myeloma.
2020 Editorial in International Journal of Molecular Sciences Int. J. Mol. Sci. 21:383 (2020)
Revisiting the pharmacological value of glucagon: An editorial for the special Issue "The biology and pharmacology of glucagon".
2020 Scientific Article in Nature metabolism Nat. Metab. 2, 192-209 (2020)
Targeted pharmacological therapy restores β-cell function for diabetes remission.
2020 Scientific Article in Nature Communications Nat. Commun. 11:113 (2020)
Differential expansion of T central memory precursor and effector subsets is regulated by division speed.
2020 Scientific Article in Clinical and translational gastroenterology Clin. Transl. Gastroenterol. 11:e00114 (2020)
A human REPIN1 gene variant: Genetic risk factor for the development of nonalcoholic fatty liver disease.
2020 Scientific Article in Atherosclerosis Atherosclerosis 296, 32-39 (2020)
Risk for cardiovascular events responds nonlinearly to carotid intima-media thickness in the KORA F4 study.
2020 Scientific Article in Radiology Radiology 294, 405-414 (2020)
Structural nerve remodeling at 3-t mr neurography differs between painful and painless diabetic polyneuropathy in type 1 or 2 diabetes.
2020 Scientific Article in Nature Communications Nat. Commun. 11:624 (2020)
Endogenous FGF21-signaling controls paradoxical obesity resistance of UCP1-deficient mice.
2020 Scientific Article in Obesity Obesity 28, 114-121 (2020)
Maternal weight, weight gain and metabolism are associated with changes in fetal heart rate and variabilit.
2020 Review in Journal of physiology and biochemistry J. Physiol. Biochem. 76, 193-211 (2020)
HYPOTHesizing about central comBAT against obesity.
2020 Scientific Article in Molecular Metabolism Mol. Metab. 31, 163-180 (2020)
NPY1R-targeted peptide-mediated delivery of a dual PPAR alpha/gamma agonist to adipocytes enhances adipogenesis and prevents diabetes progression.
2020 Scientific Article in Journal of Autoimmunity J. Autoimmun. 107:102378 (2020)
Human herpesvirus-6 is present at higher levels in the pancreatic tissues of donors with type 1 diabetes.
2020 Review in Pharmacological reviews Pharmacol. Rev. 72, 343-379 (2020)
Solute carrier transporters as potential targets for the treatment of metabolic disease.
2020 Scientific Article in Peptides Peptides 125:170237 (2020)
Predictive effect of GIPR SNP rs10423928 on glucose metabolism liver fat and adiposity in prediabetic and diabetic subjects.
2020 Scientific Article in Nature Communications Nat. Commun. 11:296 (2020)
Irp2 regulates insulin production through iron-mediated Cdkal1-catalyzed tRNA modification.
2020 Scientific Article in EMBO Reports EMBO Rep. 21:e48354 (2020)
A distinct metabolic state arises during the emergence of 2-cell-like cells.
2020 Review in Obesity Reviews Obes. Rev. 21:e12992 (2020)
Current and emerging therapies for managing hyperphagia and obesity in Prader-Willi syndrome: A narrative review.
2020 Scientific Article in Brain stimulation Brain Stimul. 13, 470-473 (2020)
Non-invasive stimulation of vagal afferents reduces gastric frequency.
2020 Scientific Article in Neuroendocrinology Neuroendocrinology 110, 929-937 (2020)
Insulin action in the hypothalamus increases second phase insulin secretion in humans.
2020 Scientific Article in Nature Biotechnology Nat. Biotechnol. 38, 293-296 (2020)
Label-free metabolic imaging by mid-infrared optoacoustic microscopy in living cells.
2020 Scientific Article in Journal of Lipid Research J. Lipid Res. 61, 10-19 (2020)
Glucometabolic consequences of acute and prolonged inhibition of fatty acid oxidation.
2020 Review in Peptides Peptides 125:170225 (2020)
Selection and progression of unimolecular agonists at the GIP, GLP-1, and glucagon receptors as drug candidates.
2020 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 105, 1196–1209 (2020)
Muscle-liver substrate fluxes in exercising humans and potential effects on hepatic metabolism.
2020 Review in Magnetic Resonance in Medicine Magn. Reson. Med. 83, 1565-1576 (2020)
Magnetic resonance imaging of obesity and metabolic disorders: Summary from the 2019 ISMRM Workshop.
2020 Scientific Article in Transplant infectious disease Transpl. Infect. Di., DOI: 10.1111/tid.13228 (2020)
Low-dose cidofovir and conversion to mTOR-based immunosuppression in polyomavirus-associated nephropathy.
2020 Scientific Article in Neuroscience Neuroscience 447, 182-190 (2020)
Specific deletion of the astrocyte leptin receptor induces changes in hippocampus glutamate metabolism, synaptic transmission and plasticity.
2020 Scientific Article in International journal of laboratory hematology Int. J. Lab. Hem., DOI: 10.1111/ijlh.13119 (2020)
Evaluation of the Atellica COAG 360 coagulation analyzer in a central laboratory of a maximum care hospital.
2020 Scientific Article in Biochimica et Biophysica Acta - Molecular Basis of Disease Biochim. Biophys. Acta-Mol. Basis Dis. 1866:165622 (2020)
In-depth phenotyping reveals common and novel disease symptoms in a hemizygous knock-in mouse model (Mut-ko/ki) of mut-type methylmalonic aciduria.
2020 Review in Chemistry and Physics of Lipids Chem. Phys. Lipids 226:104837 (2020)
Lipid nanocarriers for microRNA delivery.
2020 Scientific Article in Diabetologia Diabetologia 63, 278-286 (2020)
Plasma ascorbic acid and the risk of islet autoimmunity and type 1 diabetes: The TEDDY study.
2020 Review in Trends in Endocrinology and Metabolism Trends Endocrinol. Metab. 31, 13-24 (2020)
Growth factor-dependent and -independent activation of mTORC2.
2020 Scientific Article in Experimental Eye Research Exp. Eye Res. 190:107871 (2020)
Spectral domain - Optical coherence tomography (SD-OCT) as a monitoring tool for alterations in mouse lenses.
2020 Scientific Article in Journal of thrombosis and thrombolysis J.Thromb. Thrombolysis 49, 457–467 (2020)
Monitoring of low dabigatran concentrations: Diagnostic performance at clinically relevant decision thresholds.
2020 Scientific Article in Environmental Research Environ. Res. 180:108817 (2020)
Ambient air pollution and diabetes: A systematic review and meta-analysis.
2020 Scientific Article in Bioinformatics Bioinformatics 36, 1492-1500 (2020)
Soft windowing application to improve analysis of high-throughput phenotyping data.
2020 Scientific Article in Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet. 128, 663-666 (2020)
Clinical impact of the TCF7L2 gene rs7903146 type 2 diabetes mellitus risk polymorphism in women with gestational diabetes mellitus: Impaired glycemic control and increased need of insulin therapy.
2020 Scientific Article in Diabetes Care Diabetes Care 43, 298-305 (2020)
Empagliflozin effectively lowers liver fat content in well-controlled Type 2 Diabetes: A randomized, double-blind, phase 4, placebo-controlled trial.
2020 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 105, 14-25:dgz020 (2020)
AMPK subunits harbor largely non-overlapping genetic determinants for body fat mass, glucose- and cholesterol metabolism.
2020 Scientific Article in Haematologica - The Hematology Journal Haematologica 105, 937-950 (2020)
Glutathione peroxidase 4 and vitamin E control reticulocyte maturation, stress erythropoiesis and iron homeostasis.
2020 Scientific Article in International Journal of Obesity Int. J. Obes. 44, 428-437 (2020)
Health, pleasure, and fullness: changing mindset affects brain responses and portion size selection in adults with overweight and obesity.
2020 Review in Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet. 128, 752-770 (2020)
Circulating FGF21 levels in human health and metabolic disease.
2020 Scientific Article in Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet. 128, 804-810 (2020)
Metabolomic characteristics of fatty pancreas.
2020 Review in Current Vascular Pharmacology Curr. Vasc. Pharmacol. 18, 148-157 (2020)
Diabetes and heart failure: Is it hyperglycemia or hyperinsulinemia?
2020 Scientific Article in Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet. 128, 644-653 (2020)
Glucose responsiveness of β-cell depends on fatty acids.
2020 Review in Biotechnology Advances Biotechnol. Adv. 39:107359 (2020)
Harmonization of immunoassays for biomarkers in diabetes mellitus.
2020 Scientific Article in Archives of Physiology and Biochemistry Arch. Physiol. Biochem. 126, 139-156 (2020)
Membrane insertion and intercellular transfer of glycosylphosphatidylinositol-anchored proteins: potential therapeutic applications.
2019 Meeting abstract in Acta Ophthalmologica Acta Ophthalmol. 97 (2019)
Retinal degeneration development in Cnga1 deficient mouse.
In: Magnetoencephalography: From Signals to Dynamic Cortical Networks: Second Edition. 2019. 661-676
Fetal magnetoencephalography (fMEG).
In: Magnetoencephalography: From Signals to Dynamic Cortical Networks: Second Edition. 2019. 1227-1246
Food meets brain.
2019 Review in Diabetes mellitus Diab. Mellitus 22, 577-581 (2019)
Phenotypes of prediabetes: Pathogenesis and consequences for prediction and prevention of type 2 diabetes and cardiovascular diseases.
In: Eating Disorders and Obesity in Children and Adolescents. 2019. 79-85
Endocrine mechanisms in obesity.
Advances in Experimental Medicine and Biology In: Mitochondria in Health and in Sickness. Gewerbestrasse 11, Cham, Ch-6330, Switzerland: Springer International Publishing Ag, 2019. 143-182 (Adv. Exp. Med. Biol. ; 1158)
Investigating the role of mitochondria in type 2 diabetes lessons from lipidomics and proteomics studies of skeletal muscle and liver.
2019 Scientific Article in Stroke Stroke 50, 349-356 (2019)
Predicting early mortality of acute ischemic stroke.
2019 Review in Archives of Physiology and Biochemistry Arch. Physiol. Biochem. 11, 420-429 (2019)
Insulin-like and mimetic molecules from non-mammalian organisms: Potential relevance for drug discovery.
2019Poster: Intestinal organoids - from stem cells to metabolism and microbiome interactions, 29 September 2019, Kopenhagen. (2019)
Gradual pioneer factor expression resolves enteroendocrine lineage recruitment from intestinal stem cells.
2019 Review in Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet. 127, S97-S101 (2019)
Position paper on lipid therapy in patients with diabetes mellitus.
2019 Scientific Article in Annual International Conference of the IEEE Engineering in Medicine and Biology Society Conf. Proc. IEEE Eng. Med. Biol. Soc., 6549-6552 (2019)
Automated detection of fetal brain signals with principal component analysis.
2019 Scientific Article in Annual International Conference of the IEEE Engineering in Medicine and Biology Society Conf. Proc. IEEE Eng. Med. Biol. Soc., 5685-5689 (2019)
Fully automated subtraction of heart activity for fetal magnetoencephalography data∗.
2019 Scientific Article in Comprehensive Physiology Compr. Physiol. 10, 99-124 (2019)
Gut peptide agonism in the treatment of obesity and diabetes.
2019 Other: Opinion in Nature metabolism Nat. Metab. 1, 1171-1172 (2019)
Teaching an old dog new tricks: metformin induces body-weight loss via GDF15.
2019 Meeting abstract in Journal of Cachexia, Sarcopenia and Muscle J. Cachexia Sarcopenia Muscle, 1387 (2019)
Exploring the contribution of the liver to cancer cachexia development.
2019 Scientific Article in BMJ Open Diabetes Research & Care BMJ Open Diab. Res. Care 7:e000700 (2019)
Selecting Core Outcomes for Randomised Effectiveness trials In Type 2 diabetes (SCORE- IT): A patient and healthcare professional consensus on a core outcome set for type 2 diabetes
2019 Scientific Article in Diabetes Diabetes 69, 436-447 (2019)
Understanding diabetic neuropathy: From subclinical nerve lesions to severe nerve fiber deficits. A cross-sectional study in patients with type 2 diabetes and healthy controls.
2019 Scientific Article in Frontiers in systems neuroscience Front. Syst. Neurosci. 13:23 (2019)
Evaluating complexity of fetal MEG signals: A comparison of different metrics and their applicability.
2019 Review in Frontiers in Genetics Front. Genet. 10:1015 (2019)
Physiological and epigenetic features of yoyo dieting and weight control.
2019 EMBO Reports EMBO Rep. 20:e48133 (2019)
Signal peptide peptidase-like 2c impairs vesicular transport and cleaves SNARE proteins.
2019 Scientific Article in BMC Pediatrics BMC Pediatr. 19:488 (2019)
Neonatal body composition: Crossectional study in healthy term singletons in Germany.
2019 Review in Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet. 127, S93-S96 (2019)
Diabetes and fatty liver.
2019 Scientific Article in Scientific Reports Sci. Rep. 9:19483 (2019)
Dusp8 affects hippocampal size and behavior in mice and humans.
2019 Scientific Article in Nature Communications Nat. Commun. 10:5697 (2019)
miRNA142-3p targets Tet2 and impairs Treg differentiation and stability in models of type 1 diabetes.
2019 Scientific Article in Nature Communications Nat. Commun. 10:5686 (2019)
Glucose homeostasis is regulated by pancreatic beta-cell cilia via endosomal EphA-processing.
2019 Scientific Article in Frontiers in Neuroscience Front. Neurosci. 13:1212 (2019)
The role of tactile stimulation for expectation, perceived treatment assignment and the placebo effect in an experimental nausea paradigm.
2019 Scientific Article in Diabetes Diabetes 68, 2223-2234 (2019)
The iminosugar AMP-DNM improves satiety and activates brown adipose tissue through GLP1.
2019 Scientific Article in Nature medicine Nat. Med. 25, 1865-1872 (2019)
Prospective virome analyses in young children at increased genetic risk for type 1 diabetes.
2019 Letter to the Editor in Acta Physiologica Acta Physiol., DOI: 10.1111/apha.13427 (2019)
Rebuttal to editorial: Sodium retention by uPA in nephrotic syndrome?
2019 Meeting abstract in Chemical senses Chem. Senses 44, E75-E75 (2019)
The brain as a fat sensor? Neuronal correlates of nutritional fat intake.
2019 Scientific Article in Frontiers in Immunology Front. Immunol. 10:2568 (2019)
Gene expression-based identification of antigen-responsive CD8+ T cells on a single-cell level.
2019 Molecular Metabolism Mol. Metab. 30:264 (2019)
Pirt deficiency has subtle female-specific effects on energy and glucose metabolism in mice (vol 23, pg 75, 2019).
2019 Molecular Metabolism Mol. Metab. 30, 265-265 (2019)
Time-resolved hypothalamic open flow micro-perfusion reveals normal leptin transport across the blood-brain barrier in leptin resistant mice (vol 13, pg 77, 2018).
2019 Scientific Article in Gut (eGut) Gut 69, 1416–1422 (2019)
Metagenomics of the faecal virome indicate a cumulative effect of enterovirus and gluten amount on the risk of coeliac disease autoimmunity in genetically at risk children: The TEDDY study.
2019 Scientific Article in Scientific Reports Sci. Rep. 9:17315 (2019)
New insight into the mechanisms of ectopic fat deposition improvement after bariatric surgery.
2019 Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 14, E2 (2019)
Erratum: Diabetes und Fettleber (Diabetologie (2019) 14:(Suppl. 2) (S222-S225) (DOI: 10.1055/a-0898-9876).
2019 Review in Diabetologie, Die Diabetologie 15, 717–728 (2019)
Langzeitfolgen und Präventionsstrategien für Frauen nach Gestationsdiabetes.
2019 Scientific Article in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 14, 356-358 (2019)
Bedeutung der Insulinwirkung im menschlichen Gehirn – Bertram-Preis 2019 – eine Kurzübersicht des Preisträgers Martin Heni.
2019 Scientific Article in Kidney & Blood Pressure Research Kidney Blood Press. Res. 44, 1363-1371 (2019)
Elimination of contrast agent gadobutrol with sustained low efficiency daily dialysis compared to intermittent hemodialysis.
2019 Review in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 14, S196-S206 (2019)
Gestationsdiabetes mellitus (GDM), Diagnostik, Therapie und Nachsorge. Praxisempfehlung – Kurzfassung der S3-Leitlinie (AWMF-Registernummer: 057-008).
2019 Scientific Article in Clinical Neurophysiology Clin. Neurophysiol. 130, 2238-2254 (2019)
Changes in event-related brain responses and habituation during child development - A systematic literature review.
2019 Review in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 14, 2, S222-S225 (2019)
Diabetes und Fettleber.
2019 Review in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 14, 2, S226-S231 (2019)
Positionspapier zur Lipidtherapie bei Patienten mit Diabetes mellitus. Eine gemeinsame Stellungnahme der Kommission Fettstoffwechsel sowie der AG Herz und Diabetes der Deutschen Diabetes Gesellschaft (DDG), der Sektion Diabetologie und Stoffwechsel der Deutschen Gesellschaft für Endokrinologie (DGE), der AG Herz und Diabetes der Deutschen Gesellschaft für Kardiologie (DGK) und der gemeinsamen AG Herz – Hormone – Diabetes der DGK, DGE und DDG.
2019 Scientific Article in Molecular Cell Mol. Cell 76, 531-545.e5 (2019)
Cistromic reprogramming of the diurnal glucocorticoid hormone response by high-fat diet.
2019 Review in International Journal of Molecular Sciences Int. J. Mol. Sci. 20:5407 (2019)
Glucagon regulation of energy expenditure.
2019 Review in International Journal of Molecular Sciences Int. J. Mol. Sci. 20:5417 (2019)
β-cell maturation and identity in health and disease.
2019 Meeting abstract in Trials Trials 20 (2019)
MOUSE - Mapping OUtcomes measured in pre-clinical Studies against randomised phase 3/4 Effectiveness trials. Do core outcome sets developed for phase3/4 effectiveness trials translate to pre-clinical research?
2019 Meeting abstract in Investigative Ophthalmology & Visual Science, IOVS Invest. Ophthalmol. Vis. Sci. 60 (2019)
Interdisciplinary Communication: Ophthalmologists' letters to secondary diabetes care centers.
2019 Scientific Article in Lancet, The Lancet 394, 1519-1529 (2019)
Glycaemic durability of an early combination therapy with vildagliptin and metformin versus sequential metformin monotherapy in newly diagnosed type 2 diabetes (VERIFY): A 5-year, multicentre, randomised, double-blind trial.
2019 Scientific Article in Endocrine Connections Endocr. Connect. 8, 1363-1371 (2019)
Serum uromodulin is inversely associated with the metabolic syndrome in the KORA F4 study.
2019 Other: Opinion in Nature metabolism Nat. Metab. 1, 2-4 (2019)
The next decade of metabolism.
2019 Meeting abstract in European Journal of Human Genetics Eur. J. Hum. Genet. 27, 818-819 (2019)
A homozygous two exon deletion in UQCRH: Matching mouse and human phenotype.
2019 Scientific Article in Kidney & Blood Pressure Research Kidney Blood Press. Res. 44, 1383-1391 (2019)
Implementation of urgent start peritoneal dialysis reduces hemodialysis catheter use and hospital stay in patients with unplanned dialysis start.
2019 Meeting abstract in Xenotransplantation Xenotransplantation 26 (2019)
Studying in vivo beta cell maturation in pigs by scRNAseq.
2019 Meeting abstract in Xenotransplantation Xenotransplantation 26 (2019)
The iRFP720 pig as a novel tool for non-invasive fluorescence monitoring of NPIs transplant engraftment and growth in preclinical animal model in vivo.
2019 Review in Molecular Metabolism Mol. Metab. 30, 72-130 (2019)
Glucagon-like peptide 1 (GLP-1).
2019 Scientific Article in Scientific Reports Sci. Rep. 9:14819 (2019)
Metabolite-related dietary patterns and the development of islet autoimmunity.
2019 Scientific Article in Nature metabolism Nat. Metab. 1, 1009-1026 (2019)
Hepatic Rab24 controls blood glucose homeostasis via improving mitochondrial plasticity.
2019 Editorial in European Heart Journal Eur. Heart J. 40, 3544-3546 (2019)
The new age of radiomic risk profiling: perivascular fat at the heart of the matter.
2019 Scientific Article in Nature metabolism Nat. Metab. 1, 546-559 (2019)
4-Methylumbelliferone improves the thermogenic capacity of brown adipose tissue.
2019 Scientific Article in European Journal of Cell Biology Eur. J. Cell Biol. 98:151046 (2019)
CRN2 binds to TIMP4 and MMP14 and promotes perivascular invasion of glioblastoma cells.
2019 Scientific Article in Cell Death & Disease Cell Death Dis. 10:747 (2019)
Double knock-out of Hmga1 and Hipk2 genes causes perinatal death associated to respiratory distress and thyroid abnormalities in mice.
2019 Meeting abstract in Diabetologia Diabetologia 62, S230-S230 (2019)
Aldolase B is a marker of functional immaturity of type 2 diabetic beta cells.
2019 Meeting abstract in Diabetologia Diabetologia 62, S228-S228 (2019)
Fetuin-A inhibits functional maturation of insulin secreting beta cells.
2019 Meeting abstract in Diabetologia Diabetologia 62, S447-S448 (2019)
Gestational weight gain but not gestational diabetes associate with altered heart rate variability in 2 year old children.
2019 Meeting abstract in Diabetologia Diabetologia 62, S203-S203 (2019)
Enterovirus as triggers of disease? New insights from autoantibody positive and type 1 diabetic nPOD donors.
2019 Meeting abstract in Diabetologia Diabetologia 62, S352-S353 (2019)
Phase Ib clinical trial of IMCY-0098 in young adults with recent-onsent type 1 diabetes.
2019 Meeting abstract in Diabetologia Diabetologia 62, S213-S213 (2019)
Expression of FFA2 and FFA3 and their role in human, mouse and rat insulin secreting cells.
2019 Meeting abstract in Diabetologia Diabetologia 62, S208-S208 (2019)
Stimulation of FFA1/GPR40 raises the intracellular Ca2+ concentration via activation of TrpM3 channels in beta cells.
2019 Meeting abstract in Diabetologia Diabetologia 62, S318-S318 (2019)
Pancreatic fat cells and fetuin-A/palmitate stimulate monocyte migration and remodelling of extracellular matrix.
2019 Meeting abstract in Diabetologia Diabetologia 62, S309-S310 (2019)
Perinodal fat cells differ from other fat cell locations regarding fat accumulation, expression of cytokines, chemoattractants, adhesion molecules and ECM components.
2019 Meeting abstract in Diabetologia Diabetologia 62, S124-S124 (2019)
Empagliflozin as metabolically active compound for treatment of non-alcoholic fatty liver disease in type 2 diabetes.
2019 Meeting abstract in Diabetologia Diabetologia 62, S295-S295 (2019)
Characterisation of the gene expression of pancreatic preadipocytes and adipocytes from patients with different metabolic status.
2019 Meeting abstract in European Journal of Immunology Eur. J. Immunol. 49, 228-228 (2019)
G alpha(s)-coupled receptor agonists suppress, whereas sleep promotes integrin activation on antigen-specific T cells in humans.
2019 Meeting abstract in Diabetologia Diabetologia 62, S136-S136 (2019)
HDAC5 regulates IL-6 transcription and enhances insulin signalling in skeletal muscle.
2019 Scientific Article in Molecular Metabolism Mol. Metab. 30, 16-29 (2019)
Establishment of a high-resolution 3D modeling system for studying pancreatic epithelial cell biology in vitro.
2019 Scientific Article in Journal of Dairy Science J. Dairy Sci. 102, 11544-11560 (2019)
Mammalian target of rapamycin signaling and ubiquitin-proteasome-related gene expression in skeletal muscle of dairy cows with high or normal body condition score around calving.
Revista española de nutrición humana y dietética In:. 2019. 24-25 (Rev. Esp. Nutr. Hum. Diet. ; 23)
Edulcorantes y microbiota.
2019 Review in International Journal of Molecular Sciences Int. J. Mol. Sci. 20:4888 (2019)
Extracellular matrix remodeling of adipose Ttssue in obesity and metabolic diseases.
2019 Review in Frontiers in Genetics Front. Genet. 10:868 (2019)
Development and clinical translation of approved gene therapy products for genetic disorders.
2019 Scientific Article in Clinical Chemistry Clin. Chem. 65, 1141-1152 (2019)
Islet autoantibody standardization program 2018 workshop: Interlaboratory comparison of glutamic acid decarboxylase autoantibody assay performance.
2019 Review in TrAC Trends in Analytical Chemistry Trends Analyt. Chem. 119:115635 (2019)
Mass-spectrometric multi-omics linked to function - State-of-the-art investigations of mitochondria in systems medicine.
2019 Scientific Article in Nature Neuroscience Nat. Neurosci. 22, 1731-1742 (2019)
Cell-type-specific profiling of brain mitochondria reveals functional and molecular diversity.
2019 Scientific Article in Haematologica - The Hematology Journal Haematologica 105, 2484-2495 (2019)
Murine tissue actor disulfide mutation causes a bleeding phenotype with sex specific organ pathology and lethality.
2019 Scientific Article in EMBO Reports EMBO Rep. 20:e48552 (2019)
The glucocorticoid receptor in brown adipocytes is dispensable for control of energy homeostasis.
Advances in Experimental Medicine and Biology In:. 2019. 143-182 (Adv. Exp. Med. Biol. ; 1158)
Investigating the role of mitochondria in type 2 diabetes - lessons from lipidomics and proteomics studies of skeletal muscle and liver.
2019 Scientific Article in Molecular Metabolism Mol. Metab. 28, 73-82 (2019)
Short-term cold exposure supports human Treg induction in vivo.
2019 Scientific Article in JCI insight JCI insight 4:e126154 (2019)
The combination of loss of glyoxalase1 and obesity results in hyperglycemia.
2019 Scientific Article in Stem Cell Research Stem Cell Res. 39:101531 (2019)
Generation of a human induced pluripotent stem cell line (HMGUi002-A) from a healthy male individual.
2019 Scientific Article in Nature Communications Nat. Commun. 10:4320 (2019)
Regulation of the endosomal SNX27-retromer by OTULIN.
2019 Scientific Article in PLoS ONE PLoS ONE 14:e0222771 (2019)
Asprosin response in hypoglycemia is not related to hypoglycemia unawareness but rather to insulin resistance in type 1 diabetes.
2019 Scientific Article in Kidney & Blood Pressure Research Kidney Blood Press. Res. 44, 984-992 (2019)
Sodium-glucose cotransporter 2 (SGLT2) inhibition in kidney transplant recipients with diabetes mellitus.
2019 Scientific Article in Diabetologia Diabetologia 62, 2211-2221 (2019)
Associations of short stature and components of height with incidence of type 2 diabetes: Mediating effects of cardiometabolic risk factors.
2019 Scientific Article in Biochemistry Biochemistry 84, 954-962 (2019)
Analysis of direct effects of the CB1 receptor antagonist rimonabant on fatty acid oxidation and glycogenolysis in liver and muscle cells in vitro.
Handbook of Experimental Pharmacology In:. 2019. 399-423 (Handb. Exp. Pharmacol. ; 257)
Costs of implementing quality in research practice.
2019 Scientific Article in Journal of atherosclerosis and thrombosis J. Atheroscler. Thromb. 26, 821-834 (2019)
Visceral adiposity index as an independent marker of subclinical atherosclerosis in individuals prone to diabetes mellitus.
2019 Letter to the Editor in New England Journal of Medicine, The / NEJM N. Engl. J. Med. 381:e17 (2019)
Five-year outcomes of gastric bypass in adolescents as compared with adults.
2019 Scientific Article in Stress and health Stress and Health 35, 289-303 (2019)
The association between stressful life events and respiratory infections during the first 4 years of life: The Environmental Determinants of Diabetes in the Young study.
2019 Meeting abstract in Allergy Allergy 74, 197-198 (2019)
Effects of IL-4 receptor a blockade during allergen-specific immunotherapy in a murine model of allergic asthma.
2019 Scientific Article in Fluids and barriers of the CNS Fluids barriers CNS 16:30 (2019)
Claudin-12 is not required for blood-brain barrier tight junction function.
2019 Review in Frontiers in Immunology Front. Immunol. 10:1859 (2019)
Fighting the fire: Mechanisms of inflammatory gene regulation by the glucocorticoid receptor.
2019 Scientific Article in JAMA: Journal of the American Medical Association JAMA 322, 514-523 (2019)
Association of gluten intake during the first 5 years of Llfe with incidence of celiac disease autoimmunity and celiac disease among children at increased risk.
2019 Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz Bundesgesundheitsbl.-Gesund. 62, 1276-1277 (2019)
Ethical consideration of studies involving human subjects outside the regulatory framework: Not mandatory, but of high relevance (vol 62, pg 722, 2019).
2019 Meeting abstract in European Neuropsychopharmacology : ENP Eur. Neuropsychopharmacol. 29, 1138-1138 (2019)
Genetic and gene expression analysis in CTBP2: A gene derived from genome-wide data in anorexia nervosa and body weight regulation.
2019 Scientific Article in Scientific Reports Sci. Rep. 9:11953 (2019)
Endocardium differentiation through Sox17 expression in endocardium precursor cells regulates heart development in mice.
2019 Review in Journal of Clinical Investigation J. Clin. Invest. 130, 4058-4071 (2019)
CNS-targeting pharmacological interventions for the metabolic syndrome.
2019 Scientific Article in Nutrients Nutrients 11:1790 (2019)
Early probiotic supplementation and the risk of celiac disease in children at genetic risk.
2019 Review in Clinical & Experimental Immunology Clin. Exp. Immunol. 198, 294-305 (2019)
Birth and coming of age of islet autoantibodies.
2019 Scientific Article in Nutrients Nutrients 11:1795 (2019)
Identification of the secreted proteins originated from primary human hepatocytes and HepG2 cells.
2019 Scientific Article in FASEB Journal FASEB J. 33, 12087-12098 (2019)
Human muscular mitochondrial fusion in athletes during exercise.
2019 Review in International Journal of Molecular Sciences Int. J. Mol. Sci. 20:3445 (2019)
Glucagon, GLP-1 and thermogenesis.
2019 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 104, 6357-6370 (2019)
Plasma metabolomics to identify and stratify patients with impaired glucose tolerance.
2019 Review in Current Opinion in Cell Biology Curr. Opin. Cell Biol. 61, 48-55 (2019)
Wnt signaling: Implications in endoderm development and pancreas organogenesis.
2019 Scientific Article in Obesity Facts Obes. Facts 12, 460-475 (2019)
Leptin is not essential for obesity-associated hypertension.
2019 Review in Contact Contact 2, DOI: 10.1177/2515256419859186 (2019)
Catching lipid droplet contacts by proteomics.
2019 Scientific Article in Nucleic Acids Research Nucleic Acids Res. 47, 9069-9086 (2019)
Pre-marked chromatin and transcription factor co-binding shape the pioneering activity of Foxa2.
2019 Scientific Article in Lancet Diabetes and Endocrinology Lancet Diabet. Endocrinol. 7, 684-694 (2019)
Risk of diabetes-associated diseases in subgroups of patients with recent-onset diabetes: A 5-year follow-up study.
2019 Scientific Article in Journal of Hepatology J. Hepatol. 71, 594-602 (2019)
Genetic studies of abdominal MRI data identify genes regulating hepcidin as major determinants of liver iron concentration.
2019 Scientific Article in Scientific Data Sci. Data 6:130 (2019)
X chromosome genetic data in a Spanish children cohort, dataset description and analysis pipeline.
2019 Scientific Article in Scientific Reports Sci. Rep. 9:11211 (2019)
Genome-wide screening of mouse knockouts reveals novel genes required for normal integumentary and oculocutaneous structure and function.
2019 Scientific Article in Molecular Metabolism Mol. Metab. 28, 91-106 (2019)
alpha-Calcitonin gene-related peptide inhibits autophagy and calpain systems and maintains the stability of neuromuscular junction in denervated muscles.
2019 Scientific Article in International Journal of Epidemiology Int. J. Epidemiol. 48, 1051-1051K (2019)
Cohort Profile: The DynaHEALTH consortium - a European consortium for a life-course bio-psychosocial model of healthy ageing of glucose homeostasis.
2019 Scientific Article in Internist, Der Internist 60, 895-902 (2019)
Incretin-based co- and tri-agonists Innovative polypharmacology for the treatment of obesity and diabetes.
2019 Review in Cancer Immunology, Immunotherapy Cancer Immunol. Immunother. 68, 1855-1863 (2019)
Adhering to adhesion: Assessing integrin conformation to monitor T cells.
2019 Scientific Article in Diabetologia Diabetologia 62, 2094-2105 (2019)
Antioxidants protect against diabetes by improving glucose homeostasis in mouse models of inducible insulin resistance and obesity.
2019 Scientific Article in Stem cell research & therapy Stem Cell Res. Ther. 10:218 (2019)
Long-term culture of mesenchymal stem cells impairs ATM-dependent recognition of DNA breaks and increases genetic instability.
2019 Scientific Article in Scientific Reports Sci. Rep. 9:10261 (2019)
Glucose, adrenaline and palmitate antagonistically regulate insulin and glucagon secretion in human pseudoislets.
2019 Scientific Article in Frontiers in Neuroscience Front. Neurosci. 13:725 (2019)
Functional connectivity within the gustatory network is altered by fat content and oral fat sensitivity - A pilot study.
2019 Meeting abstract in Journal of Cerebral Blood Flow & Metabolism J. Cereb. Blood Flow Metab. 39, 575-576 (2019)
Long-term high-sugar diet increases reward-related neural responses to an acute glucose challenge as revealed by simultaneous [F-18]FDG PET/fMRI.
2019 Scientific Article in VASA Vasa 48, 368-370 (2019)
Acquired arteriovenous fistula of a finger.
2019 Scientific Article in Physiological Measurement Physiol. Meas. 40:064002 (2019)
Heart rate variability categories of fluctuation amplitude and complexity: diagnostic markers of fetal development and its disturbances.
2019 Review in Molecular Aspects of Medicine Mol. Aspects Med. 68, 90-100 (2019)
The role of brown and beige adipose tissue in glycaemic control.
2019 Scientific Article in Disease Models and Mechanisms Dis. Model. Mech. 12:dmm039156 (2019)
Mild maternal hyperglycemia in INSC93S transgenic pigs causes impaired glucose tolerance and metabolic alterations in neonatal offspring.
2019 Scientific Article in Clinical Cancer Research Clin. Cancer Res. 25, 5890-5900 (2019)
Bispecific antibodies enable synthetic agonistic receptor-transduced T cells for tumor immunotherapy.
2019 Scientific Article in BMC Medicine BMC Med. 17:125 (2019)
Landmark models to define the age-adjusted risk of developing stage 1 type 1 diabetes across childhood and adolescence.
2019 Scientific Article in Archives of Toxicology Arch. Toxicol. 93, 1609-1637 (2019)
Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations.
2019 Scientific Article in Scientific Reports Sci. Rep. 9:9299 (2019)
Identification of the fructose transporter GLUT5 (SLC2A5) as a novel target of nuclear receptor LXR.
2019 Scientific Article in BMJ Open BMJ Open 9:e028578 (2019)
Oral insulin therapy for primary prevention of type 1 diabetes in infants with high genetic risk: the GPPAD-POInT (global platform for the prevention of autoimmune diabetes primary oral insulin trial) study protocol.
2019 Review in Development / Company of Biologists Development 146:dev170506 (2019)
Concepts and limitations for learning developmental trajectories from single cell genomics.
2019 Scientific Article in Diabetes Care Diabetes Care 42, 1684-1691 (2019)
Age, HLA, and sex define a marked risk of organ-specific autoimmunity in first-degree relatives of patients with type 1 diabetes.
2019 Letter to the Editor in Hippokratia Hippokratia 22, 92 (2019)
Role of lipids in the pathophysiology of peripheral and autonomic neuropathy and cardiac function in patients with diabetes mellitus type 1. A preliminary report.
2019 Scientific Article in Psychoneuroendocrinology Psychoneuroendocrinology 108, 43-52 (2019)
Influence of subliminal intragastric fatty acid infusion on subjective and physiological responses to positive emotion induction in healthy women: A randomized trial.
2019 Scientific Article in Journal of Cellular and Molecular Medicine J. Cell. Mol. Med. 23, 5144-5153 (2019)
Metabolic signature associated with parameters of the complete blood count in apparently healthy individuals.
2019 Scientific Article in Pediatric Diabetes Pediatr. Diabetes 20, 720-727 (2019)
Identification of infants with increased type 1 diabetes genetic risk for enrollment into Primary Prevention Trials-GPPAD-02 study design and first results.
2019 Letter to the Editor in Diabetologia Diabetologia 62, 1514-1516 (2019)
Fostering improved human islet research: A European perspective.
2019 Scientific Article in American Journal of Physiology - Endocrinology and Metabolism Am. J. Physiol. Endocrinol. Metab. 317, E374-E387 (2019)
Linking bioenergetic function of mitochondria to tissue-specific molecular fingerprints.
2019 Editorial in Diabetologie, Die Diabetologie 15, 333-343 (2019)
Gestational Diabetes mellitus (GDM), Diagnostics, Therapy and Aftercare Practice Recommendation - Abstract of the S3 Guideline (AWMF Register Number: 057-008).
2019 Scientific Article in Bioinformatics Bioinformatics 35, 4834-4836 (2019)
DEUS: An R package for accurate small RNA profiling based on differential expression of unique sequences.
2019 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 104, 2801-2808 (2019)
Timing modulates the effect of sleep loss on glucose homeostasis.
2019 Meeting abstract in Radiotherapy and Oncology Radiother. Oncol. 133, S794-S795 (2019)
Impact of diabetes on outcome and toxicity of neoadjuvant (chemo)radiation for rectal cancer.
2019 Meeting abstract in Radiotherapy and Oncology Radiother. Oncol. 133, S780-S780 (2019)
Impact of diabetes on outcome and toxicity of chemoradiation for esophageal squamous cell carcinoma.
2019 Scientific Article in Nature Communications Nat. Commun. 10:2474 (2019)
Diabetes causes marked inhibition of mitochondrial metabolism in pancreatic beta-cells.
2019 Review in Traffic Traffic 20, 552-570 (2019)
Metabolic regulation through the endosomal system.
2019 Scientific Article in Radiation Oncology Radiat. Oncol. 14:97 (2019)
Positive correlation between blood glucose and radiotherapy doses to the central gustatory system in Glioblastoma Multiforme patients.
2019 Scientific Article in Clinical Laboratory Clin. Lab. 65, 845-851 (2019)
Effects of long-term storage on serum free light chain stability.
2019 Scientific Article in Diabetes Care Diabetes Care 42, 1051-1060 (2019)
Predicting islet cell autoimmunity and type 1 diabetes: An 8-year TEDDY study progress report.
2019 Scientific Article in Development / Company of Biologists Development 146:dev173849 (2019)
Comprehensive single cell mRNA profiling reveals a detailed roadmap for pancreatic endocrinogenesis.
2019 Scientific Article in JAMA network open JAMA net. open 2:e194798 (2019)
Association of serum cholesterol levels with peripheral nerve damage in patients with type 2 diabetes.
2019 Review in Diabetes Aktuell Diabetes akt. 17, 110-112 (2019)
Infektionen in der Schwangerschaft und frühen Kindheit. Risiko für Betazell-Autoimmunität und Typ-1-Diabetes?
2019 Scientific Article in Diabetes Aktuell Diabetes akt. 17, 104-107 (2019)
Stationäre Diabetestherapie und Behandlung. Jeder vierte Patient in Kliniken leidet an Diabetes.
2019 Scientific Article in Diabetes Aktuell Diabetes akt. 17, 98-100 (2019)
Prävention des Typ-2-Diabetes nach Schwangerschaftsdiabetes. Die App TRIANGLE als individueller Begleiter für junge Mütter.
2019 Scientific Article in Journal of Experimental Medicine J. Exp. Med. 216, 1700-1723 (2019)
Immune homeostasis and regulation of the interferon pathway require myeloid-derived Regnase-3.
2019 Editorial in Nature Nature 569, 342-343 (2019)
A map of beta-cell differentiation.
2019 Scientific Article in Molecular Metabolism Mol. Metab. 26, 30-44 (2019)
Multi-omics insights into functional alterations of the liver in insulin-deficient diabetes mellitus.
2019 Scientific Article in Proceedings of the National Academy of Sciences of the United States of America Proc. Natl. Acad. Sci. U.S.A. 116, 11872-11877 (2019)
Gain-of-function mutations in a member of the Src family kinases cause autoinflammatory bone disease in mice and humans.
2019 Editorial in Diabetes Aktuell Diabetes akt. 17, 96 (2019)
Vom Labor zum Patienten - Translationale Diabetesforschung.
2019 Scientific Article in PLoS ONE PLoS ONE 14:e0216110 (2019)
Dynamic modelling of an ACADS genotype in fatty acid oxidation - Application of cellular models for the analysis of common genetic variants.
2019 Review in Molecular Metabolism Mol. Metab. 25, 1-10 (2019)
What role do fat cells play in pancreatic tissue?
2019 Scientific Article in Cellular and Molecular Life Sciences - CMLS Cell. Mol. Life Sci. 76, 4551-4568 (2019)
CNDP1 knockout in zebrafish alters the amino acid metabolism, restrains weight gain, but does not protect from diabetic complications.
2019 Scientific Article in Metabolism: clinical and experimental Metabolism 97, 9-17 (2019)
Pancreatic adipocytes mediate hypersecretion of insulin in diabetes-susceptible mice.
2019 Scientific Article in Journal of Inherited Metabolic Disease J. Inherit. Metab. Dis. 42, 839-849 (2019)
Low catalytic activity is insufficient to induce disease pathology in triosephosphate isomerase deficiency.
2019 Scientific Article in Marine Drugs Mar. Drugs 17:280 (2019)
Identification of cyanobacterial strains with potential for the treatment of obesity-related co- morbidities by bioactivity, toxicity evaluation and metabolite profiling.
2019 Scientific Article in VASA Vasa 48, 186-192 (2019)
Effect of metformin treatment in patients with type 2 diabetes with respect to glyoxalase 1 activity in atherosclerotic lesions.
2019 Review in Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz Bundesgesundheitsbl.-Gesund. 62, 722-728 (2019)
Ethical consideration of studies involving human subjects outside the regulatory framework: not mandatory, but of high relevance.
2019Poster: Keystone Symposia, 10-14 February 2019, Banff, Canada. (2019)
Diffenrential effects of weight loss by calorie restriction vs. exendin-4 on liver metabolism and eWAT inflammation.
2019Poster: Keystone Symposia, 10-14 February 2019, Banff, Canada. (2019)
Adipose selective loss of Kindlin-2 causes a lean insulin resistance phenotype.
2019Poster: Keystone Symposia, 10-14 February 2019, Banff. (2019)
Beta cell specific loss of serine racemase causes hyperinsulinemia independent of insulin secretion.
2019Vortrag: EVER-Meeting 2019, 17-19 October 2019, Nizza. (2019)
Mutation in the mouse histone gene Hist2h3c1 leads to degeneration of the lens vesicle and severe microphthalmia.
2019 Scientific Article in Scientific Reports Sci. Rep. 9:6989 (2019)
Chronic dysfunction of Stromal interaction molecule by pulsed RNAi induction in fat tissue impairs organismal energy homeostasis in Drosophila.
2019 Scientific Article in Journal of Biophotonics J. Biophotonics 12:e201800439 (2019)
Capsule optoacoustic endoscopy for esophageal imaging.
2019 Review in Nutrients Nutrients 11:840 (2019)
The impact of maternal eating disorders on dietary intake and eating patterns during pregnancy: A systematic review.
2019 Scientific Article in American Journal of Physiology - Endocrinology and Metabolism Am. J. Physiol. Endocrinol. Metab. 317, https://doi.org/ 10.6084/m9.figshare.7994312.v1, E212-E233 (2019)
Chip-based sensing for release of unprocessed cell surface proteins in vitro and in serum and its (patho)physiological relevance.
2019 Scientific Article in Journal of Dental Research - JDR Online J. Dent. Res. 98, 642-651 (2019)
The saliva metabolome in association to oral health status.
2019 Scientific Article in Acta Physiologica Acta Physiol. 227:e13286 (2019)
Urokinase-type plasminogen activator (uPA) is not essential for epithelial sodium channel (ENaC)-mediated sodium retention in experimental nephrotic syndrome.
2019 Scientific Article in Neurogastroenterology and motility Neurogastroenterol. Mot. 31:e13600 (2019)
Defecatory urge increases cognitive control and intertemporal patience in healthy volunteers.
2019 Scientific Article in Journal of Dairy Science J. Dairy Sci. 102, 6571-6586 (2019)
Biogenic amines: Concentrations in serum and skeletal muscle from late pregnancy until early lactation in dairy cows with high versus normal body condition score.
2019 Scientific Article in EBioMedicine EBioMedicine 43, 562-575 (2019)
The Notch ligand DNER regulates macrophage IFN gamma release in chronic obstructive pulmonary disease.
Handbook of Experimental Pharmacology In: Brown Adipose Tissue. 2019. (Handb. Exp. Pharmacol. ; 251)
Preface.
2019 Scientific Article in Scientific Reports Sci. Rep. 9:6250 (2019)
Common patterns of gene regulation associated with Cesarean section and the development of islet autoimmunity - indications of immune cell activation.
2019 Scientific Article in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 14, 132-138 (2019)
Risikokommunikation und Inanspruchnahme von Präventionsangeboten des Diabetes mellitus Typ 2 mithilfe des Deutschen Diabetes-Risiko-Tests.
2019 Review in Diabetologie, Die Diabetologie 15, 267-277 (2019)
Genetik des Typ-2-Diabetes.
2019 Scientific Article in Molecular Cell Mol. Cell 74, 951-965.e13 (2019)
Cross-regulation between TDP-43 and paraspeckles promotes pluripotency-differentiation transition.
2019 Scientific Article in Diabetologia Diabetologia 62, 805-810 (2019)
Cytoplasmic ends of tetraspanin 7 harbour epitopes recognised by autoantibodies in type 1 diabetes.
2019 Scientific Article in Arthritis & Rheumatology Arthritis Rheum. 71, 817-828 (2019)
Association of dendritic cell signatures with autoimmune inflammation revealed by single-cell profiling.
2019 Review in Handbook of Experimental Pharmacology Handb. Exp. Pharmacol. 251, 215-237 (2019)
Regulatory small and long noncoding RNAs in brite/brown adipose tissue.
2019 Scientific Article in Cardiovascular Diabetology Cardiovasc. Diabetol. 18:46 (2019)
Effect of SGLT2 inhibitors on body composition, fluid status and renin-angiotensin-aldosterone system in type 2 diabetes: A prospective study using bioimpedance spectroscopy.
2019 Meeting abstract in European Journal of Cancer Eur. J. Cancer 110, S3-S3 (2019)
Characterization of bispecific antibodies that drive synthetic agonistic receptor - transduced T cells to mediate specific and conditional therapy in human pancreatic cancer models.
2019 Review in Handbook of Experimental Pharmacology Handb. Exp. Pharmacol. 251, 127-141 (2019)
Evolution of UCP1.
2019 Scientific Article in Experimental Eye Research Exp. Eye Res. 188:107632 (2019)
Mutation in the mouse histone gene Hist2h3c1 leads to degeneration of the lens vesicle and severe microphthalmia.
2019 Scientific Article in Molecular Metabolism Mol. Metab. 24, 149-155 (2019)
Profound weight loss induces reactive astrogliosis in the arcuate nucleus of obese mice.
2019 Developmental Cell Dev. Cell 49, 1-3 (2019)
Sorting out fate determination.
2019 Other: Opinion in Nature metabolism Nat. Metab. 1, 312-313 (2019)
Cell makeover for diabetes therapy.
2019 Scientific Article in Nature Biotechnology Nat. Biotechnol. 37, 461-468 (2019)
Inferring population dynamics from single-cell RNA-sequencing time series data.
2019 Review in Diabetologie, Die Diabetologie 15, 177-184 (2019)
Glukagon, das vergessene Hormon.
2019 Scientific Article in Toxicology Toxicology 420, 29-38 (2019)
Comparison of Aristolochic acid I derived DNA adduct levels in human renal toxicity models.
2019 Scientific Article in Neuropharmacology Neuropharmacol. 151, 55-63 (2019)
GLP-1/dexamethasone inhibits food reward without inducing mood and memory deficits in mice.
2019 Scientific Article in British Journal of Radiology, The Br. J. Radiol. 92:20180562 (2019)
MRI-based assessment and characterization of epicardial and paracardial fat depots in the context of impaired glucose metabolism and subclinical left-ventricular alterations.
2019 Review in Thrombosis and Haemostasis Thromb. Haemost. 119, 567-575 (2019)
Endocannabinoid signalling in atherosclerosis and related metabolic complications.
2019 Scientific Article in Clinical Chemistry and Laboratory Medicine Clin. Chem. Lab. Med. 57, 1261-1270 (2019)
Performance of a novel high sensitivity cardiac troponin I assay in asymptomatic hemodialysis patients - evidence for sex-specific differences.
2019 Meeting abstract in Chemical senses Chem. Senses 44, E1-E1 (2019)
Toward neuroendocrine precision medicines for metabolic diseases.
2019 Scientific Article in Diabetes Diabetes 68, 1329-1340 (2019)
Long-acting neurotensin synergizes with liraglutide to reverse obesity through a melanocortin-dependent pathway.
2019 Scientific Article in Molecular Metabolism Mol. Metab. 23, 75-81 (2019)
Pirt deficiency has subtle female-specific effects on energy and glucose metabolism in mice.
2019 Review in Acta pharmaceutica Sinica Acta Pharm. Sin. B 9, 443-454 (2019)
Highlights of the 2nd International Symposium on Tribbles and Diseases: Tribbles tremble in therapeutics for immunity, metabolism, fundamental cell biology and cancer.
2019 Scientific Article in Diabetes Care Diabetes Care 42, e56-e57 (2019)
Glucose measurements at various time points during the OGTT and their role in capturing glucose response patterns.
2019 Scientific Article in Frontiers in Endocrinology Front. Endocrin. 10:90 (2019)
Sex-specific associations of testosterone with metabolic traits.
2019 Scientific Article in Endocrine Connections Endocr. Connect. 8, 367–377 (2019)
Aip-mutated acromegaly resistant to first-generation somatostatin analogs: Long-term control with pasireotide lar in two patients.
2019 Review in Experimental Neurology Exp. Neurol. 317, 180-190 (2019)
Outcomes and clinical implications of intranasal insulin administration to the central nervous system.
2019 Scientific Article in Cell Metabolism Cell Metab. 29, 1422-1432.e3 (2019)
Phosphoproteomics reveals the GSK3-PDX1 axis as a key pathogenic signaling node in diabetic islets.
2019 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 104, 3795-3802 (2019)
Serum uromodulin is associated with but does not predict type 2 diabetes in elderly KORA F4/FF4 study participants.
2019 Scientific Article in Allergy Allergy 74, 1549-1560 (2019)
IL-4 receptor a blockade prevents sensitization and alters acute and long-lasting effects of allergen-specific immunotherapy of murine allergic asthma.
2019 Review in EMBO Reports EMBO Rep. 20:e47258 (2019)
Energy metabolism in cachexia.
2019 Scientific Article in Acta Neuropathologica Acta Neuropathol. 137, 657-673 (2019)
TCF4 (E2-2) harbors tumor suppressive functions in SHH medulloblastoma.
2019 Scientific Article in American Journal of Clinical Nutrition Am. J. Clin. Nutr. 109, 491-503 (2019)
Good practice in food-related neuroimaging.
2019 Scientific Article in Journal of Experimental Medicine J. Exp. Med. 216, 517-526 (2019)
Gαs-coupled receptor signaling and sleep regulate integrin activation of human antigen-specific T cells.
2019 Scientific Article in Computer Methods and Programs in Biomedicine Comput. Meth. Programs Biomed. 173, 35-41 (2019)
Fully Automated R-peak Detection Algorithm (FLORA) for fetal magnetoencephalographic data.
2019 Scientific Article in Cell Reports Cell Rep. 26, 3027-3036.e3 (2019)
Decreased expression of cilia genes in pancreatic islets as a risk factor for type 2 diabetes in mice and humans.
2019 Scientific Article in Frontiers in Physiology Front. Physiol. 10:262 (2019)
Genes whose gain or loss-of-function increases endurance performance in mice: a systematic literature review.
2019 Scientific Article in Journal of Clinical Investigation J. Clin. Invest. 129, 1772-1778 (2019)
Calcium-dependent blood-brain barrier breakdown by NOX5 limits postreperfusion benefit in stroke.
2019 Editorial in Diabetes, Stoffwechsel und Herz Diabetes Stoffwechs. Herz 28, 33-35 (2019)
Infantile vitamin-D-levels determine the risk for type 1-diabetes.
2019 Scientific Article in Molecular Metabolism Mol. Metab. 24, 80-97 (2019)
Point mutations in the PDX1 transactivation domain impair human beta-cell development and function.
2019 Scientific Article in Frontiers in Endocrinology Front. Endocrin. 10:72 (2019)
Gene X gene interactions highlight the role of incretin resistance for insulin secretion.
2019 Scientific Article in Molecular Systems Biology Mol. Syst. Biol. 15:e8793 (2019)
Plasma proteome profiling discovers novel proteins associated with non-alcoholic fatty liver disease.
2019 Scientific Article in Neurobiology of Disease Neurobiol. Dis. 127, 76-86 (2019)
Methylglyoxal and a spinal TRPA1-AC1-Epac cascade facilitate pain in the db/db mouse model of type 2 diabetes.
Methods in Molecular Biology In: Calcium Signalling. 2019. 197-222 (Methods Mol. Biol. ; 1925)
Assessing calcium-stimulated mitochondrial bioenergetics using the seahorse XF96 analyzer.
2019 Scientific Article in Nature metabolism Nat. Metab. 1, 222-235 (2019)
Functional identity of hypothalamic melanocortin neurons depends on Tbx3.
2019 Scientific Article in Nature Nature 567, 113-117 (2019)
The centrosome protein AKNA regulates neurogenesis via microtubule organization.
2019 Scientific Article in Nutrients Nutrients 11:337 (2019)
Autism Spectrum Disorder (ASD) with and without mental regression is associated with changes in the fecal microbiota.
2019 Scientific Article in Diabetes Diabetes 68, 502-514 (2019)
ADAMTS9 regulates skeletal muscle insulin sensitivity through extracellular matrix alterations.
2019 Scientific Article in Scientific Reports Sci. Rep. 9:1303 (2019)
Dietary niacin intake predicts the decrease of liver fat content during a lifestyle intervention.
2019 Scientific Article in American Journal of Clinical Nutrition Am. J. Clin. Nutr. 109, 288-296 (2019)
Potential effects of reduced red meat compared with increased fiber intake on glucose metabolism and liver fat content: A randomized and controlled dietary intervention study.
2019 Communications Biology Comm. Biol. 2:97 (2019)
Author Correction: Identification of genes required for eye development by high-throughput screening of mouse knockouts (Communications Biology, (2018), 1, 1, (236), 10.1038/s42003-018-0226-0).
2019 Review in Internist, Der Internist 60, 128-132 (2019)
Neues zur nichtalkoholischen Steatohepatitis.
2019 Scientific Article in American Journal of Physiology - Endocrinology and Metabolism Am. J. Physiol. Endocrinol. Metab. 316, E615-E621 (2019)
Effect of bariatric surgery on plasma GDF15 in humans.
2019 Scientific Article in Journal of Hepatology J. Hepatol. 70, 1192-1202 (2019)
Tick-tock hedgehog-mutual crosstalk with liver circadian clock promotes liver steatosis.
2019 Scientific Article in Cellular Signalling Cell. Signal. 57, 45-57 (2019)
Chemical genetic screen identifies Gapex-5/GAPVDI and STBD1 as novel AMPK substrates.
2019 Scientific Article in Pediatric Diabetes Pediatr. Diabetes 20, 263-270 (2019)
Predicting progression to type 1 diabetes from ages 3 to 6 in islet autoantibody positive TEDDY children.
2019 Scientific Article in NeuroImage - a Journal of Brain Function Neuroimage 191, 596-609 (2019)
Real-time fMRI neurofeedback training to improve eating behavior by self-regulation of the dorsolateral prefrontal cortex: A randomized controlled trial in overweight and obese subjects.
2019 Scientific Article in EMBO Reports EMBO Rep. 20:e46451 (2019)
Signal peptide peptidase-like 2c impairs vesicular transport and cleaves SNARE proteins.
2019 Scientific Article in American Journal of Clinical Nutrition Am. J. Clin. Nutr. 109, 276-287 (2019)
Disentangling the genetics of lean mass.
2019 Scientific Article in Plant Signaling & Behavior Plant Signal. Behav. 14:e1581561 (2019)
Proportional subcellular localization of Arabidopsis thaliana RabA1a.
2019 Scientific Article in Diabetes Diabetes 68, 847-857 (2019)
Genetic contribution to the divergence in type 1 diabetes risk between children from the general population and children from affected families.
2019 Scientific Article in FASEB Journal FASEB J. 33, 5924-5941 (2019)
A miR-29a-driven negative feedback loop regulates peripheral glucocorticoid receptor signaling.
2019 Scientific Article in Laboratory animals Lab. Anim. 53, 564-576 (2019)
Retrobulbar sinus injection of doxorubicin is more efficient than lateral tail vein injection at inducing experimental nephrotic syndrome in mice: A pilot study.
2019 Review in SLAS Discovery SLAS Discov. 24, 398-413 (2019)
EU-OPENSCREEN: A novel collaborative approach to facilitate chemical biology.
2019 Scientific Article in Clinical Science Clin. Sci. 133, 239-252 (2019)
Neutral endopeptidase inhibitors blunt kidney fibrosis by reducing myofibroblast formation.
2019 Scientific Article in Translational Psychiatry Transl. Psychiatry 9:7 (2019)
Cognitive impairment and autistic-like behaviour in SAPAP4-deficient mice.
2019 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 104, 1090-1098 (2019)
A polygenic risk score of lipolysis-increasing alleles determines visceral fat mass and proinsulin conversion.
2019 Scientific Article in American Journal of Physiology - Endocrinology and Metabolism Am. J. Physiol. Endocrinol. Metab. 316, E866-E879 (2019)
Intermuscular adipose tissue directly modulates skeletal muscle insulin sensitivity in humans.
2019 Scientific Article in Cell Metabolism Cell Metab. 29, 932-949.e4 (2019)
Gene-by-sex interactions in mitochondrial functions and cardio-metabolic traits.
2019 Scientific Article in Nature Communications Nat. Commun. 10:306 (2019)
E47 modulates hepatic glucocorticoid action.
2019Poster: Keystone Symposia, 11-14 February 2019, Banff, Canada. (2019)
Defining murine brown adipose tissue heterogeneity
2019 Conservation genetics Conservation genetics 20, 135-136 (2019)
The International Mouse Phenotyping Consortium (IMPC): A functional catalogue of the mammalian genome that informs conservation (vol 19, pg 995, 2018).
2019 Meeting abstract in Naunyn-Schmiedeberg's Archives of Pharmacology Naunyn-Schmiedebergs Arch. Pharmakol. 392, S39-S39 (2019)
Compensatory mechanisms for methylglyoxal detoxification in experimental & clinical diabetes.
2019 Other: Opinion in The lancet child & adolescent health Lancet Child Adolesc. Health 3, 288-290 (2019)
Screening for asymptomatic β-cell autoimmunity in young children.
2019 Meeting abstract in Naunyn-Schmiedeberg's Archives of Pharmacology Naunyn-Schmiedebergs Arch. Pharmakol. 392, S35-S35 (2019)
Tri-agonist-induced PLC activation is associated with robust insulin secretion from murine islets.
2019 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 104, 2041-2053 (2019)
The Gly385(388)arg polymorphism of the FGFR4 receptor regulates hepatic lipogenesis under healthy diet.
2019 Scientific Article in Diabetes Therapy Diabetes Ther. 10, 229-243 (2019)
Clinical trials on diabetic nephropathy: A cross-sectional analysis.
2019 Review in Acta Physiologica Acta Physiol. 225:e13249 (2019)
Proteasuria-the impact of active urinary proteases on sodium retention in nephrotic syndrome.
2019 Scientific Article in Diabetes, Obesity and Metabolism Diabetes Obes. Metab. 21, 993-1000 (2019)
Nasal insulin administration does not affect hepatic glucose production at systemic fasting insulin levels.
2019 Scientific Article in Molecular Metabolism Mol. Metab. 20, 51-62 (2019)
Optimized GIP analogs promote body weight lowering in mice through GIPR agonism not antagonism.
2019 Scientific Article in Cellular and Molecular Gastroenterology and Hepatology Cell. Mol. Gast. Hept. 7, 571-596 (2019)
A high caloric diet aggravates mitochondrial dysfunction and triggers severe liver damage in Wilson disease rats.
2019 Scientific Article in Diabetes Diabetes 68, 207-219 (2019)
Genome-wide and abdominal MRI data provide evidence that a genetically determined favorable adiposity phenotype is characterized by lower ectopic liver fat and lower risk of type 2 diabetes, heart disease, and hypertension.
2019 Scientific Article in ACS Nano ACS Nano 13, 1029-1041 (2019)
Three-dimensional quantitative co-mapping of pulmonary morphology and nanoparticle distribution with cellular resolution in non-dissected murine lungs.
2019 Scientific Article in Diabetes, Obesity and Metabolism Diabetes Obes. Metab. 21, 424-428 (2019)
Intranasal oxytocin fails to acutely improve glucose metabolism in obese men.
2019 Scientific Article in Allergy Allergy 74, 1090-1101 (2019)
House dust mite drives proinflammatory eicosanoid reprogramming and macrophage effector functions.
2019 Review in Nature Neuroscience Nat. Neurosci. 22, 7-14 (2019)
Role of astrocytes, microglia, and tanycytes in brain control of systemic metabolism.
2019 Review in Nature Reviews - Endocrinology Nat. Rev. Endocrinol. 15, 155-171 (2019)
Modelling the endocrine pancreas in health and disease.
2019 Scientific Article in Developmental Biology Dev. Biol. 445, 256-270 (2019)
Dual embryonic origin of the mammalian enteric nervous system.
2019 Scientific Article in Molecular Metabolism Mol. Metab. 20, 28-37 (2019)
Preadipocytes of obese humans display gender-specific bioenergetic responses to glucose and insulin.
2019 Review in Nature Reviews - Endocrinology Nat. Rev. Endocrinol. 15, 90-104 (2019)
Emerging hormonal-based combination pharmacotherapies for the treatment of metabolic diseases.
2019 Scientific Article in Endocrine Endocrine 64, 486-495 (2019)
Metabolomics signature associated with circulating serum selenoprotein P levels.
2019 Scientific Article in Molecular Metabolism Mol. Metab. 19, 97-106 (2019)
Diet-dependent function of the extracellular matrix proteoglycan Lumican in obesity and glucose homeostasis.
2019 Scientific Article in Zeitschrift für Orthopädie und Unfallchirurgie Z. Orthop. Unfallchir. 157, 173-181 (2019)
Assessment of the influence of diabetes mellitus and malnutrition on the postoperative complication rate and quality of life of patients in a clinic focused on trauma surgery.
2019 Scientific Article in Pediatric Diabetes Pediatr. Diabetes 20, 86-92 (2019)
Maternal dietary supplement use and development of islet autoimmunity in the offspring: TEDDY study.
2019 Editorial in Journal of Steroid Biochemistry and Molecular Biology, The J. Steroid Biochem. Mol. Biol. 186, 1-3 (2019)
Paramount importance of sample quality in pre-clinical and clinical research-Need for standard operating procedures (SOPs).
2019 Scientific Article in Gastroenterology Gastroenterology 156, 692-707.e7 (2019)
Alternative splice forms of CYLD mediate ubiquitination of SMAD7 to prevent TGFB signaling and promote colitis.
2019 Scientific Article in Journal of Dairy Science J. Dairy Sci. 102, 754-767 (2019)
Acylcarnitine profiles in serum and muscle of dairy cows receiving conjugated linoleic acids or a control fat supplement during early lactation.
2019 Scientific Article in Gastroenterology Gastroenterology 156, 203-217.e20 (2019)
Levels of the autophagy-related 5 protein affect progression and metastasis of pancreatic tumors in mice.
2019 Scientific Article in Acta Paediatrica Acta Paediatr. 108, 940-944 (2019)
Blood draws up to 3% of blood volume in clinical trials are safe in children.
2019 Scientific Article in Molecular Neurobiology Mol. Neurobiol. 56, 4215-4230 (2019)
Crybb2 mutations consistently affect Schizophrenia endophenotypes in mice.
2019 Scientific Article in International Journal of Obesity Int. J. Obes. 43, 1305-1318 (2019)
Fluorescent blood-brain barrier tracing shows intact leptin transport in obese mice.
2019 Scientific Article in Diabetic Medicine Diabetic Med. 36, 366-375 (2019)
Physical activity is associated with lower insulin and C-peptide during glucose challenge in children and adolescents with family background of diabetes.
2019 Scientific Article in Psychoneuroendocrinology Psychoneuroendocrinology 99, 1-7 (2019)
Intensifying sleep slow oscillations does not improve metabolic control in healthy men.
2019 Review in Lancet Diabetes and Endocrinology Lancet Diabet. Endocrinol. 7, 313-324 (2019)
Non-alcoholic fatty liver disease: causes, diagnosis, cardiometabolic consequences, and treatment strategies.
2019 Scientific Article in European Radiology Eur. Radiol. 29, 1094-1103 (2019)
Characteristics and associated risk factors of diverticular disease assessed by magnetic resonance imaging in subjects from a Western general population.
2019 Review in Pharmacology & Therapeutics. Pharmacol. Ther. 194, 132-144 (2019)
Myocardial metabolism in heart failure: Purinergic signalling and other metabolic concepts.
2019 Scientific Article in Clinical Cancer Research Clin. Cancer Res. 25, 1505-1516 (2019)
A five-microRNA signature predicts survival and disease control of patients with head and neck cancer negative for HPV-infection.
2019 Scientific Article in Journal of Steroid Biochemistry and Molecular Biology, The J. Steroid Biochem. Mol. Biol. 185, 80-89 (2019)
Initial characterization of human DHRS1 (SDR19C1), a member of the short chain dehydrogenase/reductase superfamily.
2019 Review in Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet. 127, 203-214 (2019)
Effects of the reactive metabolite methylglyoxal on cellular signalling, insulin action and metabolism – What we know in mammals and what we can learn from yeast.
2018 Scientific Article in Diabetologia Diabetologia 61, 1167-1179 (2018)
Increased Ifi202b/IFI16 expression stimulates adipogenesis in mice and humans.
2018 Scientific Article in PLoS ONE PLoS ONE 13:e0189886 (2018)
Integrative network analysis highlights biological processes underlying GLP-1 stimulated insulin secretion: A DIRECT study.
2018 Scientific Article in Nutrition & metabolism Nutr. Metab. 15:90 (2018)
An 8-week diet high in cereal fiber and coffee but free of red meat does not improve beta-cell function in patients with type 2 diabetes mellitus: A randomized controlled trial.
2018 Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 13, E1 (2018)
Erratum: Gestationsdiabetes mellitus (GDM), Diagnostik, Therapie und Nachsorge:: Praxisempfehlung - Kurzfassung der S3-Leitlinie (AWMF-Registernummer: 057-008) (Diabetologie und Stoffwechsel (2018) 13:Suppl 2 (S174-S184) DOI: 10.1055/a-0598-3468).
2018 Meeting abstract in European Heart Journal Eur. Heart J. 39, 390-391 (2018)
Primary cilium-autophagy-cell cycle axis defects impair cardiac progenitor specification in hypoplastic left heart syndrome.
2018 Diabetes Diabetes 67, 343-344 (2018)
Erratum. Adipocyte glucocorticoid Receptor deficiency attenuates aging- and HFD-induced obesity and impairs the feeding-fasting transition. Diabetes 2017;66:272-286.
2018 Scientific Article in Experimental Cell Research Exp. Cell Res. 372, 25-34 (2018)
Matrix mineralization controls gene expression in osteoblastic cells.
2018 Scientific Article in Pediatric Diabetes Pediatr. Diabetes 19, 1025-1033 (2018)
Family adjustment to diabetes diagnosis in children: Can participation in a study on type 1 diabetes genetic risk be helpful?
2018 Scientific Article in Molecular and Cellular Proteomics Mol. Cell. Proteomics 17, 1824-1836 (2018)
Quality control analysis in real-time (QC-ART): A tool for real-time quality control assessment of mass spectrometry-based proteomics data.
2018 Scientific Article in Hepatology communications Hepat. Commun. 2, 69-83 (2018)
Serine/threonine protein kinase 25 antisense oligonucleotide treatment reverses glucose intolerance, insulin resistance, and nonalcoholic fatty liver disease in mice.
2018 Scientific Article in Computer methods in biomechanics and biomedical engineering : imaging & visualization Comp. meth. biomech. biomed. engin. imag. visual. 6, 51-58 (2018)
Shape estimation of subcutaneous adipose tissue using an articulated statistical shape model.
2018 Scientific Article in Endocrinology, Diabetes & Metabolism Case Reports Endocrinol. Diabetes Metab. Case Rep. 2018:18-0094 (2018)
Unusual high blood glucose in ketoacidosis as first presentation of type 1 diabetes mellitus.
2018 Meeting abstract in Acta Ophthalmologica Acta Ophthalmol. 96, 4-4 (2018)
Animal case.
2018 Scientific Article in npj Aging and Mechanisms of Disease npj Aging Mech. Dis. 4:4 (2018)
Blocking negative effects of senescence in human skin fibroblasts with a plant extract.
2018 Review in Geburtshilfe und Frauenheilkunde Geburtsh. u. Frauenheilk. 78, 1219-1231 (2018)
Gestational Diabetes Mellitus (GDM) - Diagnosis, Treatment and Follow-Up. Guideline of the DDG and DGGG (S3 Level, AWMF Registry Number 057/008, February 2018).
2018 Review in Diabetes Aktuell Diabetes akt. 16, 290-294 (2018)
Diabetes mellitus vor und nach Nierentransplantation.
2018 Scientific Article in Communications Biology Comm. Biol. 1:236 (2018)
Identification of genes required for eye development by high-throughput screening of mouse knockouts.
2018 Scientific Article in Frontiers in psychiatry Front. Psychiatr. 9:706 (2018)
Effects of placebo interventions on subjective and objective markers of appetite-a randomized controlled trial.
2018 Scientific Article in Nutrients Nutrients 10:1859 (2018)
Acute endothelial benefits of fat restriction over carbohydrate restriction in type 2 diabetes mellitus: beyond carbs and fats.
2018 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 103, 1393-1401 (2018)
Insulin and estrogen independently and differentially reduce macronutrient intake in healthy men.
2018 Scientific Article in EMBO Journal, The EMBO J. 37:e99291 (2018)
Developmental and functional heterogeneity of white adipocytes within a single fat depot.
2018 Scientific Article in Biochimica et Biophysica Acta - Molecular Basis of Disease Biochim. Biophys. Acta-Mol. Basis Dis. 1865, 2083-2093 (2018)
A mouse model for intellectual disability caused by mutations in the X-linked 2 '-O-methyltransferase Ftsj1 gene.
2018 Scientific Article in International Journal of Obesity Int. J. Obes. 42, 2057-2061 (2018)
The anorexigenic peptide neurotensin relates to insulin sensitivity in obese patients after BPD or RYGB metabolic surgery.
2018 Scientific Article in Diabetic Medicine Diabetic Med. 35, 1375-1382 (2018)
Characteristics of high- and low-risk individuals in the PRIORITY study: Urinary proteomics and mineralocorticoid receptor antagonism for prevention of diabetic nephropathy in Type 2 diabetes.
2018 Scientific Article in Journal of Medicinal Chemistry J. Med. Chem. 61, 11144-11157 (2018)
Celastrol promotes weight loss in diet-induced obesity by inhibiting the protein tyrosine phosphatases PTP1B and TCPTP in the hypothalamus.
2018 Scientific Article in Cell Reports Cell Rep. 25, 3241-3251.e5 (2018)
The aryl hydrocarbon receptor pathway defines the time frame for restorative neurogenesis.
2018 Scientific Article in EMBO Molecular Medicine EMBO Mol. Med. 10:e9456 (2018)
Alternative oxidase-mediated respiration prevents lethal mitochondrial cardiomyopathy.
2018 Meeting abstract in Transplant international Transpl. Int. 31, 32-32 (2018)
Effects of MTOR-IS on malignancy and survival following renal transplantation: A systematic review and meta-analysis of randomized trials with a minimum follow-up of 24 months.
2018 Nature Communications Nat. Commun. 9:4975 (2018)
Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes (vol 9, 4304, 2018).
2018 Scientific Article in Frontiers in Endocrinology Front. Endocrin. 9, DOI: 10.3389/fendo.2018.00663 (2018)
Metabolic and cognitive outcomes of subchronic once-daily intranasal insulin administration in healthy men.
2018 Scientific Article in Nutrients Nutrients 10:1314 (2018)
Dissociation of fatty liver and insulin resistance in I148M PNPLA3 carriers: Differences in diacylglycerol (DAG) FA18:1 lipid species as a possible explanation.
2018 Scientific Article in Frontiers in Endocrinology Front. Endocrin. 9:673 (2018)
Family history of diabetes is associated with delayed fetal postprandial brain activity.
2018 Scientific Article in GigaScience GigaScience 7, DOI: 10.1093/gigascience/giy137 (2018)
A network-based conditional genetic association analysis of the human metabolome.
2018 Review in Journal of Internal Medicine J. Intern. Med. 284, 581-602 (2018)
Peptide-based multi-agonists: A new paradigm in metabolic pharmacology.
2018 Scientific Article in BMC Genomics BMC Genomics 19:794 (2018)
Norepinephrine triggers an immediate-early regulatory network response in primary human white adipocytes.
2018 Scientific Article in Nutrients Nutrients 10:1800 (2018)
Molecular fingerprints of iron parameters among a population-based sample.
2018 Editorial in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 13, 394-395 (2018)
Dicarbonyl compounds affect cardiovascular mortality in type 2 diabetes comment.
2018 Scientific Article in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 13, S174-S184 (2018)
Gestational diabetes mellitus (GDM), diagnosis, therapy and follow-up.
2018 Scientific Article in Diabetes Diabetes 67, 2329-2336 (2018)
Reduction in white blood cell, neutrophil, and red blood cell counts related to sex, HLA, and islet autoantibodies in Swedish TEDDY children at increased risk for type 1 diabetes.
2018 Scientific Article in Diabetes Diabetes 67, 324-336:db180315 (2018)
TGR5 activation promotes stimulus-secretion coupling of pancreatic -cells via a PKA-dependent pathway.
2018 Scientific Article in Diabetologie, Die Diabetologie 14, 509-518 (2018)
Gehirn und Glukosestoffwechsel.
2018 Scientific Article in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 13, S205-S208 (2018)
Diabetes und Fettleber.
2018 Scientific Article in Diabetes Research and Clinical Practice Diabetes Res. Clin. Pract. 146, 251-257 (2018)
Genetic variation in TCF7L2 rs7903146 and history of GDM negatively and independently impact on diabetes-associated metabolic traits.
2018 Scientific Article in Clinical Chemistry Clin. Chem. 64, 810-819 (2018)
Quality control of serum and plasma by quantification of (4E, 14Z)-sphingadienine-C18-1-phosphate uncovers common preanalytical errors during handling of whole blood.
2018 Meeting abstract in Wiener medizinische Wochenschrift Wien. Med. Wochenschr. 130, 353-354 (2018)
Paternal circadian arrhythmia affects offspring health and feeding behaviour.
2018 Scientific Article in Nutrition & metabolism Nutr. Metab. 15:78 (2018)
Circulating glutamate concentration as a biomarker of visceral obesity and associated metabolic alterations.
2018 Meeting abstract in Wiener medizinische Wochenschrift Wien. Med. Wochenschr. 130, 348-348 (2018)
Posture of adipose Mice under hypoxia reduces Hyperglycemia without Improving Insulin Sensitivity.
2018 Scientific Article in Molecules Molecules 23:2823 (2018)
Comparative gene expression analysis in WM164 melanoma cells revealed that beta-beta-Dimethylacrylshikonin leads to ROS generation, loss of mitochondrial membrane potential, and autophagy induction.
2018 Scientific Article in Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet. 126, 20-29 (2018)
Impact of brain fatty acid signaling on peripheral insulin action in mice.
2018 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 103, 4373-4383 (2018)
The expression of aldolase B in islets is negatively associated with insulin secretion in humans.
2018 Scientific Article in Cell Reports Cell Rep. 25, 1425-1435 (2018)
MICU1 confers protection from MCU-dependent manganese toxicity.
2018 Scientific Article in Nature Nature 562, 589-594 (2018)
The human gut microbiome in early-onset type 1 diabetes from the TEDDY study.
2018 Review in Current Diabetes Reports Curr. Diab. Rep. 18:136 (2018)
The Environmental Determinants of Diabetes in the Young (TEDDY) Study: 2018 Update.
2018 Scientific Article in Nature Nature 562, 583-588 (2018)
Temporal development of the gut microbiome in early childhood from the TEDDY study.
2018 Scientific Article in Journal of the American Heart Association J. Am. Heart Assoc. 7:e009807 (2018)
Limitations of specific coagulation rests for direct oral anticoagulants: A critical analysis.
2018 Scientific Article in Open Biology Open Biol. 8:180147 (2018)
Suitability of hepatocyte cell lines HepG2, AML12 and THLE-2 for investigation of insulin signalling and hepatokine gene expression.
2018 Review in Pflügers Archiv Pflugers Arch. 471, 383-396 (2018)
Hepatokinesa novel group of exercise factors.
2018 Review in Trends in cancer Trends Cancer 4, 849-860 (2018)
Cancer cachexia: More than skeletal muscle wasting.
2018 Scientific Article in Nature Communications Nat. Commun. 9:4304 (2018)
Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes.
2018 Scientific Article in Developmental Cell Dev. Cell 47, 205-221.e7 (2018)
Organellar proteomics and phospho-proteomics reveal subcellular teorganization in diet-induced hepatic steatosis.
2018 Meeting abstract in Oncology Research and Treatment Oncol. Res. Treat. 41, 140-141 (2018)
The EUTOS long-term survival (ELTS) score is superior to the Sokal score for prognosis of probabilities of dying of chronicphase chronic myeloid leukaemia.
2018 Scientific Article in Statistics in Medicine Stat. Med. 37, 4771-4788 (2018)
Nonlinear association structures in flexible Bayesian additive joint models.
2018 Review in Endocrine Reviews Endocr. Rev. 39, 719-738 (2018)
Targeting the incretin/glucagon system with triagonists to treat diabetes.
2018 Review in Clinical & Experimental Immunology Clin. Exp. Immunol. 195, 15-24 (2018)
Enterovirus infection and type 1 diabetes: Unraveling the crime scene.
2018 Scientific Article in Diabetes Diabetes 68, 119-130 (2018)
Time-resolved autoantibody profiling facilitates stratification of preclinical type 1 diabetes in children.
2018 Other: Opinion in Lancet, The Lancet 392, 2142-2144 (2018)
Twice the benefits with twincretins?
2018 Scientific Article in Molecular Metabolism Mol. Metab. 18, 143-152 (2018)
Compensatory mechanisms for methylglyoxal detoxification in experimental & clinical diabetes.
2018 Scientific Article in Journal of Medical Genetics J. Med. Genet. 56, 602-605 (2018)
Progression from islet autoimmunity to clinical type 1 diabetes is influenced by genetic factors: Results from the prospective TEDDY study.
2018 Review in Current Diabetes Reports Curr. Diab. Rep. 18:124 (2018)
Pancreas pathology during the natural history of type 1 diabetes.
Nova Science Publishers, 2018.
Glycosylphosphatidylinositol-anchored proteins and their release from cells: From phenomenon to meaning.
2018 Editorial in Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet. 126, 590-591 (2018)
Diabetic pulmopathy: A new clinical challenge for diabetology.
2018 Scientific Article in Obesity Obesity 26, 1457-1466 (2018)
Associations of maternal diabetes during pregnancy with overweight in offspring: Results from the prospective TEDDY study.
2018 Scientific Article in PLoS ONE PLoS ONE 13:e0201959 (2018)
Molecular epidemiology of enteroviruses in young children at increased risk of type 1 diabetes.
2018 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 103, 3299-3309 (2018)
BMI-independent effects of gestational diabetes on human placenta.
2018 Scientific Article in Analytica Chimica Acta Anal. Chim. Acta 1037, 293-300 (2018)
Serum or plasma, what is the difference? Investigations to facilitate the sample material selection decision making process for metabolomics studies and beyond.
2018 Scientific Article in Angiology Angiology 69, 854-860 (2018)
Periaortic adipose tissue compared with peribrachial adipose tissue mass as markers and possible modulators of cardiometabolic risk.
2018 Scientific Article in Aging Cell Aging Cell 17:e12810 (2018)
Loss of periostin occurs in aging adipose tissue of mice and its genetic ablation impairs adipose tissue lipid metabolism.
2018 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 103, 3260-3266 (2018)
No correlation of pancreatic fat and β-cell function in young women with and without a history of gestational diabetes.
2018 Scientific Article in Journal of Public Mental Health J. Public Health, DOI: 10.1007/s10389-018-0981-x (2018)
Feasibility and organization of a population-based screening for pre-symptomatic type 1 diabetes in children – Evaluation of the Fr1da study.
2018 Scientific Article in Cellular and Molecular Gastroenterology and Hepatology Cell. Mol. Gast. Hept. 6, 429-449 (2018)
Glycemic variability promotes both local invasion and metastatic colonization by pancreatic ductal adenocarcinoma.
2018 Scientific Article in World Journal of Gastroenterology World J. Gastroenterol. 24, 4028-4035 (2018)
Adiponectin affects the mechanical responses in strips from the mouse gastric fundus.
2018 Review in Diabetologia Diabetologia 61, 2252-2258 (2018)
Immunological biomarkers for the development and progression of type 1 diabetes.
2018 Review in Current Diabetes Reports Curr. Diab. Rep. 18:106 (2018)
Enteroviral infections as a trigger for type 1 diabetes.
2018 Scientific Article in Neuropsychopharmacology Neuropsychopharmacology 43, 2292-2298 (2018)
Overnight memory consolidation facilitates rather than interferes with new learning of similar materials-a study probing NMDA receptors.
2018 Scientific Article in Frontiers in Physiology Front. Physiol. 9:1278 (2018)
Impact of intrauterine growth restriction on cognitive and motor development at 2 years of age.
2018 Scientific Article in Human Molecular Genetics Hum. Mol. Genet. 27, 3099-3112 (2018)
A collective diabetes cross in combination with a computational framework to dissect the genetics of human obesity and Type 2 diabetes.
2018 Meeting abstract in Investigative Ophthalmology & Visual Science, IOVS Invest. Ophthalmol. Vis. Sci. 59 (2018)
Red flags of diabetic retinopathy (DR) in patients with Type 1 Diabetes mellitus (T1DM) using HbA1c level and antihypertensive medication.
2018 Scientific Article in Molecular Metabolism Mol. Metab. 18, 42-50 (2018)
Glucose tolerance and insulin sensitivity define adipocyte transcriptional programs in human obesity.
2018 Review in Pharmacological Research Pharmacol. Res. 137, 11-24 (2018)
Uncoupling proteins as a therapeutic target to protect the diabetic heart.
2018 Scientific Article in Metabolomics Metabolomics 14:128 (2018)
Characterization of missing values in untargeted MS-based metabolomics data and evaluation of missing data handling strategies.
2018 Meeting abstract in Diabetologia Diabetologia 61, S205-S206 (2018)
Fetuin-A impairs islet differentiation and function via inhibition of TGFbeta-1 signalling.
2018 Meeting abstract in Diabetologia Diabetologia 61, S259-S259 (2018)
Interindividual susceptibility to type 2 diabetes in mice: Hepatic transcriptome and DNA methylome profiling.
2018 Scientific Article in Stem Cell Reports Stem Cell Rep. 11, 897-911 (2018)
Reproducibility of molecular phenotypes after long-term differentiation to human iPSC-derived neurons: A multi-site omics study.
2018 Scientific Article in Journal of Visualized Experiments J. Vis. Exp. 143:e58601 (2018)
Measuring and interpreting oxygen consumption rates in whole fly head segments.
2018 Meeting abstract in Diabetologia Diabetologia 61, S271-S271 (2018)
Linking of bioenergetic function of mitochondria to tissue-specific molecular fingerprints in mice and humans.
2018 Meeting abstract in Diabetologia Diabetologia 61, S78-S78 (2018)
Effects of increased fiber and reduced red meat intake, combined with caloric restriction, on cardiometabolic risk: A randomised and controlled dietary intervention study.
2018 Meeting abstract in Diabetologia Diabetologia 61, S289-S290 (2018)
Differences in extracellular matrix expression in pancreatic fat cells of non-diabetic, pre-diabetic and diabetic individuals.
2018 Meeting abstract in Diabetologia Diabetologia 61, S122-S122 (2018)
Acetate stimulates insulin secretion of human pancreatic microislets.
2018 Meeting abstract in Diabetologia Diabetologia 61, S72-S72 (2018)
Brain insulin action stimulates pancreatic insulin secretion: Results from hyperglycaemic clamps.
2018 Meeting abstract in Diabetologia Diabetologia 61, S336-S336 (2018)
Insulin influences mindset-induced brain response and behaviour on portion size selection for lunch.
2018 Meeting abstract in Diabetologia Diabetologia 61, S194-S194 (2018)
The impact of cilia-genes on pancreatic beta cell replication and the risk of type 2 diabetes.
2018 Scientific Article in Metabolism: clinical and experimental Metabolism 88, 22-30 (2018)
cGMP-dependent protein kinase I (cGKI) modulates human hepatic stellate cell activation.
2018 Scientific Article in Molecular Metabolism Mol. Metab. 17, 112-121 (2018)
Periodized low protein-high carbohydrate diet confers potent, but transient, metabolic improvements.
2018 Scientific Article in Molecular and Cellular Proteomics Mol. Cell. Proteomics 17, 2358-2370 (2018)
Comparative secretome analyses of primary murine white and brown adipocytes reveal novel adipokines.
2018 Scientific Article in Journal of Immunological Methods J. Immunol. Methods 463, 54-60 (2018)
CD4+ T cell activation, function, and metabolism are inhibited by low concentrations of DMSO.
2018 Scientific Article in Diabetes Diabetes 67, 2456-2465 (2018)
Celastrol-induced weight loss is driven by hypophagia and independent from UCP1.
2018 Meeting abstract in Allergy Allergy 73, 103-104 (2018)
From pollen to fungal spore allergy: Alternaria spores under differing environmental regimes and the need for an electronic Spore Information Network (eSPIN) in Bavaria, Germany.
2018 Meeting abstract in Allergy Allergy 73, 200-200 (2018)
Potential of upper airway mediators as biomarkers for asthmatic lung.
2018 Meeting abstract in Allergy Allergy 73, 233-233 (2018)
A thermosensitive hydrogel as delivery system for immunomodulatory substances and allergens during allergen-specific immunotherapy.
2018 Meeting abstract in Allergy Allergy 73, 232-232 (2018)
Sustained inhibition of the IL4/IL13 receptor complex during allergen specific immunotherapy.
2018 Review in Archives of Biochemistry and Biophysics Arch. Biochem. Biophys. 656, 1-18 (2018)
The release of glycosylphosphatidylinositol-anchored proteins from the cell surface.
2018 Scientific Article in Pediatric Diabetes Pediatr. Diabetes 19, 1238-1242 (2018)
Fasting hypoglycemia is associated with disease progression in presymptomatic early stage type 1 diabetes.
2018 Scientific Article in Molecular Metabolism Mol. Metab., DOI: 10.1016/j.molmet.2018.07.002 (2018)
Chronic d-serine supplementation impairs insulin secretion.
2018 Review in Pharmacological reviews Pharmacol. Rev. 70, 712-746 (2018)
Anti-obesity therapy: From rainbow pills to polyagonists.
2018 Review in Diabetologie, Die Diabetologie 14, 486-492 (2018)
Mit Big Data zur personalisierten Diabetesprävention.
2018 Scientific Article in Nature microbiology Nat. Microbiol. 3, 1161–1174 (2018)
Male offspring born to mildly ZIKV-infected mice are at risk of developing neurocognitive disorders in adulthood.
2018 Review in Current neuropharmacology Curr. Neuropharmacol. 16, 1111-1121 (2018)
Oxytocin and eating disorders: A narrative review on emerging findings and perspectives.
2018 Scientific Article in Nature Communications Nat. Commun. 9:3432 (2018)
p53 in AgRP neurons is required for protection against diet-induced obesity via JNK1.
2018 Scientific Article in Cell Cell 174, 1571-1585.e11 (2018)
Atlas of circadian metabolism reveals system-wide coordination and communication between clocks.
2018 Scientific Article in Atherosclerosis Atherosclerosis 276, 140-147 (2018)
Ldlr-/- and ApoE-/- mice better mimic the human metabolite signature of increased carotid intima media thickness compared to other animal models of cardiovascular disease.
2018 Scientific Article in Nature Communications Nat. Commun. 9:3129 (2018)
Dietary stearic acid regulates mitochondria in vivo in humans.
2018 Scientific Article in Nephrology Dialysis Transplantation Nephrol. Dial. Transplant. 33, 1419-1427 (2018)
Systemic haemodynamics in haemodialysis: Intradialytic changes and prognostic significance.
2018 Scientific Article in Acta Physiologica Acta Physiol. 224:e13060 (2018)
Plasma kallikrein activates the epithelial sodium channel invitro but is not essential for volume retention in nephrotic mice.
2018 Scientific Article in Respiration Respiration 96, 29-40 (2018)
Breathlessness and restrictive lung disease: AniImportant diabetes-related feature in patients with type 2 diabetes.
2018 Scientific Article in Metabolites Metabolites 8:45 (2018)
Night shift work affects urine metabolite profiles of nurses with early chronotype.
2018 Scientific Article in PLoS Biology PLoS Biol. 16:e2005651 (2018)
The mitochondrial transporter SLC25A25 links ciliary TRPP2 signaling and cellular metabolism.
2018 Scientific Article in EMBO Journal, The EMBO J.:e94813 (2018)
RNA editing of Filamin A pre-mRNA regulates vascular contraction and diastolic blood pressure.
2018 Scientific Article in Biochemical and Biophysical Research Communications Biochem. Biophys. Res. Commun. 503, 2770-2777 (2018)
The heterozygous R155C VCP mutation: Toxic in humans! Harmless in mice?
2018 Scientific Article in Life Science Alliance Life Sci. All. 1:e201800106 (2018)
Neuron-specific inactivation of Wt1 alters locomotion in mice and changes interneuron composition in the spinal cord.
2018 Scientific computing world Sci. Comp. World August/September, 24-25 (2018)
How connecting data may lead to discoveries in medical research?
2018 Scientific Article in Cardiovascular Diabetology Cardiovasc. Diabetol. 17:120 (2018)
Metabolomic profiling implicates adiponectin as mediator of a favorable lipoprotein profile associated with NT-proBNP.
2018 Scientific Article in Scientific Reports Sci. Rep. 8:12262 (2018)
The human metabolic profile reflects macro- and micronutrient intake distinctly according to fasting time.
2018 Scientific Article in Contemporary clinical trials communications Contemp. Clin. Trails Comm. 11, 170-173 (2018)
Recruiting young pre-symptomatic children for a clinical trial in type 1 diabetes: Insights from the Fr1da insulin intervention study.
2018 Scientific Article in PLoS Biology PLoS Biol. 16:e2005886 (2018)
Transcriptional programming of lipid and amino acid metabolism by the skeletal muscle circadian clock.
2018 Scientific Article in Science Science 361:eaar7191 (2018)
Shifting the limits in wheat research and breeding using a fully annotated reference genome.
2018 Scientific Article in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 13, 263-269 (2018)
Knowledge of patients and health professionals about diabetes-related eye diseases (Risk Factors, Screening, Treatment).
2018 Scientific Article in Diabetes Diabetes 67, 1200-1205 (2018)
Circulating fetuin - A and risk of type 2 diabetes : A mendelian randomization analysis.
2018 Scientific Article in Diabetes Aktuell Diabetes akt. 16, 52-54 (2018)
Neue Studie zur Prävention von Typ-1-Diabetes.
2018 Scientific Article in Ageing research reviews Ageing Res. Rev. 47, 214-277 (2018)
Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases.
2018 Scientific Article in Diabetes/Metabolism Research and Reviews Diabetes Metab. Res. Rev. 34:e3049 (2018)
Regional differences in type 2 diabetes treatment and outcomes in Germany-An analysis of the German DPV and DIVE registries.
2018 Scientific Article in Cellular Signalling Cell. Signal. 51, 13-22 (2018)
An incretin-based tri-agonist promotes superior insulin secretion from murine pancreatic islets via PLC activation.
2018 Scientific Article in Pediatric Diabetes Pediatr. Diabetes 19, 20-27 (2018)
ISPAD Clinical Practice Consensus Guidelines 2018: Stages of type 1 diabetes in children and adolescents.
2018 Scientific Article in Scientific Reports Sci. Rep. 8:11335 (2018)
Streptozotocin-induced beta-cell damage, high fat diet, and metformin administration regulate Hes3 expression in the adult mouse brain.
2018 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 103, 3856-3868 (2018)
Hepatic steatosis is associates with adverse molecular signatures in subjects without diabetes.
2018 Scientific Article in Analytica Chimica Acta Anal. Chim. Acta 1032, 18-31 (2018)
Dilution correction for dynamically influenced urinary analyte data.
2018 Scientific Article in Atherosclerosis Atherosclerosis 276, 140-147 (2018)
Ldlr(-/-) and ApoE(-/-) mice better mimic the human metabolite signature of increased carotid intima media thickness compared to other animal models of cardiovascular disease.
2018 Editorial in Frontiers in Physiology Front. Physiol. 9:891 (2018)
Editorial: The evolution of endothermy-from patterns to mechanisms.
2018 Scientific Article in Scientific Reports Sci. Rep. 8:10723 (2018)
Quantitative proteomic characterization of cellular pathways associated with altered insulin sensitivity in skeletal muscle following high-fat diet feeding and exercise training.
2018 Scientific Article in Diabetologia Diabetologia 61, 2319–2332 (2018)
Associations of maternal type 1 diabetes with childhood adiposity and metabolic health in the offspring: A prospective cohort study.
2018 Review in Trends in Pharmacological Sciences Trends Pharmacol. Sci. 39, 685-694 (2018)
Ghrelin and LEAP-2: Rivals in energy metabolism.
2018 Scientific Article in Integrative and comparative biology Integ. & comp. biol. 58, 495-505 (2018)
Comparing electron leak in vertebrate muscle mitochondria.
2018 Scientific Article in Journal of Lipid Research J. Lipid Res. 59, 1649-1659 (2018)
Circulating HDL levels control hypothalamic astrogliosis via apoA-I.
2018 Scientific Article in Cellular Physiology and Biochemistry Cell. Physiol. Biochem. 46, 713-726 (2018)
Carnosine catalyzes the formation of the oligo/polymeric products of methylglyoxal.
2018 Scientific Article in Clinical Immunology Clin. Immunol. 194, 87-91 (2018)
Novel minor HLA DR associated antigens in type 1 diabetes.
2018 Scientific Article in EMBO Molecular Medicine EMBO Mol. Med. 10:e8613 (2018)
Cited4 is a sex-biased mediator of the antidiabetic glitazone response in adipocyte progenitors.
2018 Scientific Article in Journal of Diabetes Research J. Diabetes Res. 2018, 9391845 (2018)
Intralymphatic glutamic acid decarboxylase (GAD)-alum administration induced Th2-like specific immunomodulation in responder patients: a pilot clinical trial in type 1 diabetes.
2018 Scientific Article in PLoS ONE PLoS ONE 13:e0198016 (2018)
Palmitate and insulin counteract glucose-induced thioredoxin interacting protein (TXNIP) expression in insulin secreting cells via distinct mechanisms.
2018 Scientific Article in Obesity Obesity 26, 895-902 (2018)
Neural food reward processing in successful and unsuccessful weight maintenance.
2018 Scientific Article in Obesity Facts Obes. Facts 11, 93-108 (2018)
The effect of SH2B1 variants on expression of leptin- and insulin-induced pathways in murine hypothalamus.
2018 Scientific Article in Diabetologie, Die Diabetologie 14, 231-233 (2018)
Behandlung des Typ-1-Diabetes im Frühstadium: eine Kasuistik.
2018 Scientific Article in Transplant international Transpl. Int. 31, 751-760 (2018)
Cell cycle arrest and cell death correlate with the extent of ischaemia and reperfusion injury in patients following kidney transplantation – results of an observational pilot study.
2018 Editorial in Diabetologie, Die Diabetologie 14, 212-213 (2018)
Früherkennung und präventive Behandlung des Typ-1-Diabetes.
2018 Review in Diabetologie, Die Diabetologie 14, 221-223 (2018)
Evaluation of the Fr1da screening: From an epidemiological perspective.
2018 Review in Diabetologie, Die Diabetologie 14, 234-239 (2018)
Typ-1-Diabetes im asymptomatischen Frühstadium: Orales Insulin zur präventiven Behandlung.
2018 Review in Diabetologie, Die Diabetologie 14, 214-220 (2018)
Früherkennung des Typ-1-Diabetes in der Fr1da-Studie: Diagnosestellung im asymptomatischen Stadium.
2018 Review in Diabetologie, Die Diabetologie 14, 240-244 (2018)
Früherkennung und Primärprävention des Typ-1-Diabetes: „Global Platform for the Prevention of Autoimmune Diabetes“ (GPPAD).
2018 Scientific Article in Diabetes, Obesity and Metabolism Diabetes Obes. Metab. 20, 1793-1797 (2018)
Effects of resveratrol supplementation on liver fat content in overweight and insulin-resistant subjects: A randomized, double-blind, placebo-controlled clinical trial.
2018 Scientific Article in European Journal of Radiology Eur. J. Radiol. 105, 261-268 (2018)
Assessment of the degree of abdominal myosteatosis by magnetic resonance imaging in subjects with diabetes, prediabetes and healthy controls from the general population.
2018 Scientific Article in Toxicology Letters Toxicol. Lett. 115, E5536-E5545 (2018)
Activated integrins identify functional antigen-specific CD8+ T cells within minutes after antigen stimulation.
2018 Scientific Article in Molecular Metabolism Mol. Metab., DOI: 10.1016/j.molmet.2018.06.015 (2018)
Metabolic syndrome and extensive adipose tissue inflammation in morbidly obese Göttingen minipigs.
2018 Scientific Article in International Journal of Epidemiology Int. J. Epidemiol. 47, 2070-2081 (2018)
Comparison of metabolite networks from four German population-based studies.
2018 Scientific Article in Scientific Reports Sci. Rep. 8:9810 (2018)
Instability of personal human metabotype is linked to all-cause mortality.
2018 Scientific Article in American Journal of Clinical Nutrition Am. J. Clin. Nutr. 108, 127-135 (2018)
Fat label compared with fat content: gastrointestinal symptoms and brain activity in functional dyspepsia patients and healthy controls.
2018 Scientific Article in Diabetes Diabetes 67, 1773-1782 (2018)
Glucagon receptor signaling regulates energy metabolism via hepatic farnesoid X receptor and fibroblast growth factor 21.
2018 Scientific Article in Cell Reports Cell Rep. 23, 3112-3125 (2018)
Prediction of adipose browning capacity by systematic integration of transcriptional profiles.
2018 Scientific Article in Cell Metabolism Cell Metab. 28, 159-+ (2018)
Cardiolipin synthesis in brown and beige fat mitochondria is essential for systemic energy homeostasis.
2018 Scientific Article in Diabetologia Diabetologia 61, 1644-1649 (2018)
Autoantibodies to N-terminally truncated GAD improve clinical phenotyping of individuals with adult-onset diabetes: Action LADA 12.
2018 Scientific Article in Journal of Visualized Experiments J. Vis. Exp.:e57642 (2018)
Induction of nephrotic syndrome in mice by retrobulbar injection of doxorubicin and prevention of volume retention by sustained release aprotinin.
2018 Scientific Article in Lancet Diabetes and Endocrinology Lancet Diabet. Endocrinol. 6, 714-724 (2018)
Transition from metabolic healthy to unhealthy phenotypes and association with cardiovascular disease risk across BMI categories in 90 257 women (the Nurses' Health Study): 30 year follow-up from a prospective cohort study.
2018 Review in Journal of Endocrinology J. Endocrinol. 238, R109-R119 (2018)
Are peptide conjugates the golden therapy against obesity?
2018 Scientific Article in Molecular Metabolism Mol. Metab. 13, 77-82 (2018)
Time-resolved hypothalamic open flow micro-perfusion reveals normal leptin transport across the blood-brain barrier in leptin resistant mice.
2018 Scientific Article in Circulation Circulation 138, 2007-2020 (2018)
Dicer in macrophages prevents atherosclerosis by promoting mitochondrial oxidative metabolism.
2018 Scientific Article in Science Signaling Sci. Signal. 11:eaai7838 (2018)
Jak-TGF beta cross-talk links transient adipose tissue inflammation to beige adipogenesis.
2018 Scientific Article in Journal of Nutritional Biochemistry, The J. Nutr. Biochem. 57, 189-196 (2018)
Dietary protein dilution limits dyslipidemia in obesity through FGF21-driven fatty acid clearance.
2018 Scientific Article in Acta Diabetologica Acta Diabetol. 55, 881-884 (2018)
Searching peripheral blood mononuclear cells of children with viral respiratory tract infections preceding islet autoimmunity for viruses by high-throughput sequencing.
2018 Scientific Article in Maternal & Child Nutrition Matern. Child Nutr. 14:e12611 (2018)
Milk feeding and first complementary foods during the first year of life in the TEDDY study.
2018 Scientific Article in International Journal of Obesity Int. J. Obes. 42, 1249-1264 (2018)
Maternal smoking during pregnancy and offspring overweight: Is there a dose-response relationship? An individual patient data meta-analysis.
2018 Scientific Article in Appetite Appetite 127, 195-202 (2018)
Just add water: Effects of added gastric distention by water on gastric emptying and satiety related brain activity.
2018 Scientific Article in Clinical Chemistry and Laboratory Medicine Clin. Chem. Lab. Med. 56, E177-E180 (2018)
Cellular markers of eryptosis are altered in type 2 diabetes.
2018Poster: 2nd German-French Conference on Diabetes Research, 19-20 April 2018 (2018)
Primary cilia regulate transferrin endocytosis and iron homeostasis
2018 Scientific Article in Aging Aging 10, 1103-1132 (2018)
Small extracellular vesicles and their miRNA cargo are anti-apoptotic members of the senescence-associated secretory phenotype.
2018 Scientific Article in Molecular Metabolism Mol. Metab. 11, 145-159 (2018)
A computational biology approach of a genome-wide screen connected miRNAs to obesity and type 2 diabetes.
2018 Scientific Article in Diabetes Research and Clinical Practice Diabetes Res. Clin. Pract. 142, 19-25 (2018)
Switching to insulin glargine 300 U/mL: Is duration of prior basal insulin therapy important?
2018 Scientific Article in Journal of Hypertension J. Hypertens. 36, 1555-1562 (2018)
Correlation of MRI-derived adipose tissue measurements and anthropometric markers with prevalent hypertension in the community.
2018 Scientific Article in Journal of Lipid Research J. Lipid Res. 59, 452-461 (2018)
Impact of dietary ω3 polyunsaturated fatty acid supplementation on brown and brite adipocyte function.
2018 Review in Medizinische Monatsschrift für Pharmazeuten Med. Monatsschr. Pharm. 41, 105-109 (2018)
Immune preventive approaches for type-1-diabetes.
2018 Scientific Article in British Journal of Radiology, The Br. J. Radiol. 3:20180019 (2018)
Inter- and intra-observer variability of an anatomical landmark-based, manual segmentation method by MRI for the assessment of skeletal muscle fat content and area in subjects from the general population.
2018 Scientific Article in Cardiovascular Diabetology Cardiovasc. Diabetol. 17, 88:88 (2018)
Association between abdominal adiposity and subclinical measures of left-ventricular remodeling in diabetics, prediabetics and normal controls without history of cardiovascular disease as measured by magnetic resonance imaging: Results from the KORA-FF4 Study.
2018 Review in Journal of Physiology - Paris J. Physiol. 596, 2717-2733 (2018)
Pharmacological modulation of mitochondrial calcium homeostasis.
2018 Scientific Article in BMC Pediatrics BMC Pediatr. 18:154 (2018)
Effect of increased enteral protein intake on plasma and urinary urea concentrations in preterm infants born at < 32 weeks gestation and < 1500 g birth weight enrolled in a randomized controlled trial - a secondary analysis.
2018 Scientific Article in PLoS ONE PLoS ONE 13:e0194975 (2018)
Effects of mTOR-Is on malignancy and survival following renal transplantation: A systematic review and meta-analysis of randomized trials with a minimum follow-up of 24 months.
2018 Scientific Article in Diabetes Care Diabetes Care 41, 1068-1075 (2018)
Risk factors for incident diabetic polyneuropathy in a cohort with screen-detected type 2 diabetes followed for 13 years: Addition-Denmark.
2018 Scientific Article in PLoS Medicine PLoS Med. 15:e1002548 (2018)
Genetic scores to stratify risk of developing multiple islet autoantibodies and type 1 diabetes: A prospective study in children.
2018 Scientific Article in Diabetes Care Diabetes Care 41, 907-910 (2018)
Leptin replacement reestablishes brain insulin action in the hypothalamus in congenital leptin deficiency.
2018 Scientific Article in Analytica Chimica Acta Anal. Chim. Acta 1022, 70-80 (2018)
Quantification of steroid hormones in plasma using a surrogate calibrant approach and UHPLC-ESI-QTOF-MS/MS with SWATH-acquisition combined with untargeted profiling.
2018 Scientific Article in Diabetic Medicine Diabetic Med. 35, 1420-1424 (2018)
No further improvement in pregnancy-related outcomes in the offspring of mothers with pre-gestational diabetes in Bavaria, Germany, between 2001 and 2016.
2018 Scientific Article in Scientific Reports Sci. Rep. 8:7745 (2018)
Single nucleotide polymorphisms in the G-protein coupled receptor kinase 5 (GRK5) gene are associated with plasma LDL-cholesterol levels in humans.
2018 Scientific Article in Diabetic Medicine Diabetic Med. 35, 954-963 (2018)
The first 142 amino acids of glutamate decarboxylase do not contribute to epitopes recognized by autoantibodies associated with Type 1 diabetes.
2018 Scientific Article in Journal of Visualized Experiments J. Vis. Exp. 2018:e56752 (2018)
Real-time analysis of Ttanscription factor binding, transcription, translation, and turnover to display global events during cellular activation.
2018 Scientific Article in Hormone molecular biology and clinical investigation Horm. Mol. Biol. Clin. Investig. 34:20170082 (2018)
Circulating steroid levels as correlates of adipose tissue phenotype in premenopausal women.
2018 Scientific Article in Conservation genetics Conservation genetics 19, 995-1005 (2018)
The International Mouse Phenotyping Consortium (IMPC): A functional catalogue of the mammalian genome that informs conservation.
2018 Scientific Article in Kidney International Kidney Int. 94, 49-59 (2018)
The elevation of circulating fibroblast growth factor 23 without kidney disease does not increase cardiovascular disease risk.
2018 Scientific Article in PLoS Genetics PLoS Genet. 14:e1007329 (2018)
Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population.
2018 Scientific Article in European Journal of Medicinal Chemistry Eur. J. Med. Chem. 155, 61-76 (2018)
Structure-based design and profiling of novel 17 beta-HSD14 inhibitors.
2018 Review in The journal of experimental biology J. Exp. Biol. 221, 1:jeb162958 (2018)
Heterogeneity of adipose tissue in development and metabolic function.
2018 Scientific Article in Cancer Cell Cancer Cell 33, 770-784.e6 (2018)
Adipocyte p62/SQSTM1 suppresses tumorigenesis through opposite regulations of metabolism in adipose tissue and tumor.
2018 Scientific Article in Frontiers in Cellular Neuroscience Front. Cell. Neurosci. 12:57 (2018)
Mob2 insufficiency disrupts neuronal migration in the developing cortex.
2018 Scientific Article in Annals of Neurology Ann. Neurol. 83, 588-598 (2018)
Diabetic neuropathy differs between type 1 and type 2 diabetes: Insights from magnetic resonance neurography.
2018 Scientific Article in Diabetologia Diabetologia 61, 1484–1490 (2018)
Characteristics of slow progression to diabetes in multiple islet autoantibody-positive individuals from five longitudinal cohorts: The SNAIL study.
2018 Scientific Article in Appetite Appetite 125, 492-501 (2018)
Eating less or more - Mindset induced changes in neural correlates of pre-meal planning.
2018 Scientific Article in Cell Reports Cell Rep. 22, 3072-3086 (2018)
Diet, genetics, and the gut microbiome drive dynamic changes in plasma metabolites.
2018 Review in The journal of experimental biology J. Exp. Biol. 121, 1:jeb169425 (2018)
Insights into brown adipose tissue evolution and function from non-model organisms.
2018 Scientific Article in Cell Metabolism Cell Metab. 27, 1294-1308.e7 (2018)
The polycomb-dependent epigenome controls beta cell dysfunction, dedifferentiation, and diabetes.
2018 Review in Frontiers in Physiology Front. Physiol. 9:553 (2018)
Genes whose gain or loss-of-function increases skeletal muscle mass in mice: A systematic literature review.
2018 Scientific Article in Acta Diabetologica Acta Diabetol. 55, 585-592 (2018)
Urine levels of 5-aminoimidazole-4-carboxamide riboside (AICAR) in patients with type 2 diabetes.
2018 Scientific Article in Nutrients Nutrients 10:547 (2018)
A vitamin E-enriched antioxidant diet interferes with the acute adaptation of the liver to physical exercise in mice.
2018 Scientific Article in Chemical Communications Chem. Commun. 54, 5426-5429 (2018)
hIAPP forms toxic oligomers in plasma.
2018 Scientific Article in Pigment Cell & Melanoma Research Pigment Cell Melanoma Res. 31, 693-707 (2018)
Melanocyte development in the mouse tail epidermis requires the Adamts9 metalloproteinase.
2018 Scientific Article in Nature Communications Nat. Commun. 9:1990 (2018)
Bacterial encapsulins as orthogonal compartments for mammalian cell engineering.
2018 Scientific Article in Molecular Metabolism Mol. Metab. 9, 168-175 (2018)
Efficacy of vildagliptin for prevention of postpartum diabetes in women with a recent history of insulin-requiring gestational diabetes: A phase II, randomized, double-blind, placebo-controlled study.
2018 Scientific Article in Investigative Radiology Invest. Radiol. 53, 357-364 (2018)
Phenotypic multiorgan involvement of subclinical disease as quantified by magnetic resonance imaging in subjects with prediabetes, diabetes, and normal glucose tolerance.
2018 Scientific Article in Peptides Peptides 100, 18-23 (2018)
Controlled intramolecular antagonism as a regulator of insulin receptor maximal activity.
2018 Scientific Article in Scientific Reports Sci. Rep. 8:7547 (2018)
Intrauterine smoke exposure deregulates lung function, pulmonary transcriptomes, and in particular insulin-like growth factor (IGF)-1 in a sex-specific manner.
2018 Scientific Article in Molecular Metabolism Mol. Metab. 9, 187-191 (2018)
Exercise increases circulating GDF15 in humans.
2018 Scientific Article in Molecular Metabolism Mol. Metab. 9, 57-68 (2018)
Genome-wide analysis of PDX1 target genes in human pancreatic progenitors.
2018 Scientific Article in International Journal of Radiation Oncology, Biology, Physics Int. J. Radiat. Oncol. Biol. Phys. 101, 965-984 (2018)
Micro-imaging of brain cancer radiotherapy using phase-contrast computed tomography.
2018 Scientific Article in PLoS Biology PLoS Biol. 16:e2005019 (2018)
Laboratory mouse housing conditions can be improved using common environmental enrichment without compromising data.
2018 Scientific Article in EMBO Molecular Medicine EMBO Mol. Med. 10:e8349 (2018)
Cholesterol metabolism promotes B-cell positioning during immune pathogenesis of chronic obstructive pulmonary disease.
2018 Review in Pharmacogenomics Pharmacogenomics 19, 577-587 (2018)
Pharmacogenetics of oral antidiabetic therapy.
2018 Scientific Article in Frontiers in Immunology Front. Immunol. 9:587 (2018)
RNase H2 loss in murine astrocytes results in cellular defects reminiscent of nucleic acid-mediated autoinflammation.
2018 Scientific Article in Scientific Reports Sci. Rep. 8:5975 (2018)
Defective immuno- and thymoproteasome assembly causes severe immunodeficiency.
2018 Scientific Article in JCI insight JCI insight 3:98864 (2018)
Mesenchymal TNFR2 promotes the development of polyarthritis and comorbid heart valve stenosis.
2018 Scientific Article in Developmental Biology Dev. Biol. 435, 130-137 (2018)
Neural tube closure depends on expression of Grainyhead-like 3 in multiple tissues.
2018 Scientific Article in Cell Metabolism Cell Metab. 27, 926-934.e8 (2018)
Elevated levels of the reactive metabolite methylglyoxal recapitulate progression of type 2 diabetes.
2018Poster: Federation of European Neuroscience Societies Forum, 7-11 July 2018, Berlin. (2018)
Identifying underlying mechanisms of voluntary activity by mining large data sets of genetically modified mouse lines.
2018 Scientific Article in Hearing Research Hear. Res. 363, 70-77 (2018)
Fetal auditory evoked responses to onset of amplitude modulated sounds. A fetal magnetoencephalography (fMEG) study.
2018 Scientific Article in British Journal of Radiology, The Br. J. Radiol. 91 (2018)
The role of visceral and subcutaneous adipose tissue measurements and their ratio by magnetic resonance imaging in subjects with prediabetes, diabetes and healthy controls from a general population without cardiovascular disease.
2018 Scientific Article in Diabetes, Obesity and Metabolism Diabetes Obes. Metab. 20, 1563-1577 (2018)
Safety of intranasal human insulin: A review.
2018 Scientific Article in Journal of Biological Chemistry, The J. Biol. Chem. 293, 4845-4859 (2018)
High-glucose toxicity is mediated by AICAR-transformylase/ IMP cyclohydrolase and mitigated by AMP-activated protein kinase in Caenorhabditis elegans.
2018 Scientific Article in JCI insight JCI insight 3:e98212 (2018)
A peripheral blood transcriptomic signature predicts autoantibody development in infants at risk of type 1 diabetes.
2018 Scientific Article in Circulation Circulation 137, 2592-2608 (2018)
Inhibition of endothelial notch signaling impairs fatty acid transport and leads to metabolic and vascular remodeling of the adult heart.
2018 Scientific Article in Frontiers in Endocrinology Front. Endocrin. 9:82 (2018)
Prediction of glucose tolerance without an oral glucose tolerance test.
2018 Review in Current Opinion in Clinical Nutrition & Metabolic Care Curr. Opin. Clin. Nutr. Metab. Care 21, 164-167 (2018)
Skeletal muscle mass is controlled by the MRF4-MEF2 axis.
2018 Scientific Article in Cellular Physiology and Biochemistry Cell. Physiol. Biochem. 45, 625-638 (2018)
Fetal serum metabolites are independently associated with gestational diabetes mellitus.
2018 Scientific Article in Molecular Metabolism Mol. Metab. 11, 113-128 (2018)
Growth hormone receptor-deficient pigs resemble the pathophysiology of human Laron syndrome and reveal altered activation of signaling cascades in the liver.
2018 Scientific Article in European Heart Journal Eur. Heart J. 39, 2301-2310 (2018)
Altered metabolism distinguishes high-risk from stable carotid atherosclerotic plaques.
2018 Scientific Article in Peptides Peptides 102, 26-30 (2018)
Relationship between cerebrospinal fluid concentrations of orexin A/hypocretin-1 and body composition in humans.
2018 Editorial in Clinical Gastroenterology and Hepatology Clin. Gastroenterol. Hepatol. 16, 1043-1045 (2018)
Nonalcoholic fatty liver disease and mortality.
2018 Scientific Article in PLoS Biology PLoS Biol. 16:e2003992 (2018)
Mitochondria are physiologically maintained at close to 50 °C.
2018 Review in Journal of Peptide Science J. Pept. Sci. 24:e3056 (2018)
Max Bergmann award lecture: Macromolecular medicinal chemistry as applied to metabolic diseases.
2018 Scientific Article in Advanced functional materials Adv. Func. Mat. 28:1706793 (2018)
Genetically controlled lysosomal entrapment of superparamagnetic ferritin for multimodal and multiscale imaging and actuation with low tissue attenuation.
2018 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 103, 2050-2060 (2018)
Comprehensive metabolic profiling reveals a lipid-rich fingerprint of free thyroxine far beyond classic parameters.
2018 Meeting abstract in Clinical Cancer Research Clin. Cancer Res. 24, 56-56 (2018)
Combined targeting of the Ewing sarcoma transcriptional program by blocking epigenetic readers and transcription initiation via EWS-FLI1.
2018 Meeting abstract in Clinical Cancer Research Clin. Cancer Res. 24, 57-57 (2018)
The endochondral bone protein CHM1 sustains an undifferentiated, invasive phenotype promoting lung metastasis in Ewing sarcoma.
2018 Scientific Article in Magnetic Resonance in Medicine Magn. Reson. Med. 79, 2784-2794 (2018)
Spontaneous mechanical and electrical activities of human calf musculature at rest assessed by repetitive single-shot diffusion-weighted MRI and simultaneous surface electromyography.
2018 Scientific Article in Scientific Reports Sci. Rep. 8:2736 (2018)
Oxytocin curbs calorie intake via food-specific increases in the activity of brain areas that process reward and establish cognitive control.
2018 Scientific Article in Peptides Peptides 100, 236-242 (2018)
Ghrelin regulation of glucose metabolism.
2018 Scientific Article in Journal of Neuroinflammation J. Neuroinflamm. 15:35 (2018)
Calcineurin A beta deficiency ameliorates HFD-induced hypothalamic astrocytosis in mice.
2018 Review in Peptides Peptides 100, 190-201 (2018)
Gut hormone polyagonists for the treatment of type 2 diabetes.
2018 Scientific Article in Journal of Nutrition J. Nutr. 148, 77-85 (2018)
Short-term overfeeding with dairy cream does not modify gut permeability, the fecal microbiota, or glucose metabolism in young healthy men.
2018 Scientific Article in Scientific Reports Sci. Rep. 8:4199 (2018)
Rapid and transient oxygen consumption increase following acute HDAC/KDAC inhibition in Drosophila tissue.
2018 Scientific Article in Diabetes, Obesity and Metabolism Diabetes Obes. Metab. 20, 1593-1601 (2018)
Pharmacokinetics of metformin in patients with gastrointestinal intolerance.
2018 Scientific Article in Journal of Neurochemistry J. Neurochem. 145, 258-270 (2018)
Faim2 contributes to neuroprotection by erythropoietin in transient brain ischemia.
2018 Scientific Article in Molecular Metabolism Mol. Metab. 9, 156-167 (2018)
TRPC proteins contribute to development of diabetic retinopathy and regulate glyoxalase 1 activity and methylglyoxal accumulation.
2018 Scientific Article in Endocrine-Related Cancer Endocr. Relat. Cancer 25, L19-L22 (2018)
Higher prevalence of lymph node metastasis in prostate cancer in patients with diabetes.
2018 Review in Experimental Physiology Exp. Physiol. 103, 157-169 (2018)
Crosslink between calcium and sodium signalling.
2018 Scientific Article in Journal of Bone and Mineral Research J. Bone Min. Res. 33, 875-887 (2018)
Genetic and molecular insights into genotype-phenotype relationships in osteopathia striata with cranial sclerosis (OSCS) through the analysis of novel mouse Wtx mutant alleles.
2018 Scientific Article in Journal of Steroid Biochemistry and Molecular Biology, The J. Steroid Biochem. Mol. Biol. 178, 312-321 (2018)
Models including plasma levels of sphingomyelins and phosphatidylcholines as diagnostic and prognostic biomarkers of endometrial cancer.
2018 Scientific Article in Human Molecular Genetics Hum. Mol. Genet. 27, 1106-1121 (2018)
Deep molecular phenotypes link complex disorders and physiological insult to CpG methylation.
2018 Scientific Article in Proceedings of the National Academy of Sciences of the United States of America Proc. Natl. Acad. Sci. U.S.A. 115, E2348-E2357 (2018)
Epigenetic alterations in longevity regulators, reduced life span, and exacerbated aging-related pathology in old father offspring mice.
2018 Review in Environment International Environ. Int. 114, 77-86 (2018)
Epigenetics as a mechanism linking developmental exposures to long-term toxicity.
2018 Scientific Article in Cancer Research Cancer Res. 78, 2513-2523 (2018)
Extracellular citrate affects critical elements of cancer cell metabolism and supports cancer development in vivo.
2018 Scientific Article in Nature Communications Nat. Commun. 9:288 (2018)
Identification of genetic elements in metabolism by high-throughput mouse phenotyping.
2018 Scientific Article in Scientific Reports Sci. Rep. 8:737 (2018)
The effect of differentiation and TGFβ on mitochondrial respiration and mitochondrial enzyme abundance in cultured primary human skeletal muscle cells.
2018 Scientific Article in Cellular Physiology and Biochemistry Cell. Physiol. Biochem. 45, 614-624 (2018)
Cord blood lysophosphatidylcholine 16:1 is positively associated with birth weight.
2018 Scientific Article in Diabetes Care Diabetes Care 41, 522-530 (2018)
Early infant diet and islet autoimmunity in the TEDDY Study.
2018 Scientific Article in Scientific Reports Sci. Rep. 8:1116 (2018)
Epigallocatechin gallate (EGCG) reduces the intensity of pancreatic amyloid fibrils in human islet amyloid polypeptide (hIAPP) transgenic mice.
2018 Scientific Article in Journal of Autoimmunity J. Autoimmun. 89, 90-100 (2018)
Identification of non-HLA genes associated with development of islet autoimmunity and type 1 diabetes in the prospective TEDDY cohort.
2018 Scientific Article in Scientific Reports Sci. Rep. 8:1388 (2018)
Attentional and physiological processing of food images in functional dyspepsia patients: A pilot study.
2018 Scientific Article in Scientific Reports Sci. Rep. 8:1366 (2018)
Maternal whole blood cell miRNA-340 is elevated in gestational diabetes and inversely regulated by glucose and insulin.
2018 Scientific Article in Molecular Metabolism Mol. Metab. 9, 4-14 (2018)
Respiromics - An integrative analysis linking mitochondrial bioenergetics to molecular signatures.
2018 Review in Nature Reviews - Endocrinology Nat. Rev. Endocrinol. 14, 140-162 (2018)
Animal models of obesity and diabetes mellitus.
2018 Review in Seminars in Immunopathology Semin. Immunopathol. 40, 215-224 (2018)
Hemostasis, endothelial stress, inflammation, and the metabolic syndrome.
2018 Scientific Article in Diabetes Diabetes 67, 146-154 (2018)
Plasma 25-hydroxyvitamin D concentration and risk of islet autoimmunity.
2018 Scientific Data Sci. Data 5:180002 (2018)
Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.
2018 American Journal of Hematology Am. J. Hematol. 93, 154-154 (2018)
Mitotic figure in the peripheral blood smear.
2018 Scientific Article in Radiation and Environmental Biophysics Radiat. Environ. Biophys. 57, 99-113 (2018)
Lifetime study in mice after acute low-dose ionizing radiation: A multifactorial study with special focus on cataract risk.
2018 Scientific Article in Redox Biology Redox Biol. 15, 12-21 (2018)
The NADPH organizers NoxO1 and p47phox are both mediators of diabetes-induced vascular dysfunction in mice.
2018 Scientific Article in Cancer Letters Cancer Lett. 415, 129-150 (2018)
Diabetes as risk factor for pancreatic cancer: Hyperglycemia promotes epithelial-mesenchymal-transition and stem cell properties in pancreatic ductal epithelial cells.
2018 Scientific Article in Journal of Psychiatric Research J. Psychiatr. Res. 97, 89-93 (2018)
Depressive symptoms, impaired glucose metabolism, high visceral fat, and high systolic blood pressure in a subgroup of women with recent gestational diabetes.
2018 Scientific Article in Appetite Appetite 123, 7-13 (2018)
Detection thresholds for four different fatty stimuli are associated with increased dietary intake of processed high-caloric food.
2018 Scientific Article in Nature medicine Nat. Med. 24, 62-72 (2018)
A proteolytic fragment of histone deacetylase 4 protects the heart from failure by regulating the hexosamine biosynthetic pathway.
2018 Scientific Article in Journal of Diabetes and its Complications J. Diab. Complic. 32, 130-138 (2018)
Modulation of glutathione peroxidase activity by age-dependent carbonylation in glomeruli of diabetic mice.
2018 Scientific Article in Metabolomics Metabolomics 14:18 (2018)
High-throughput extraction and quantification method for targeted metabolomics in murine tissues.
2018 Scientific Article in Acta Diabetologica Acta Diabetol. 55, 263–270 (2018)
A novel LIPS assay for insulin autoantibodies.
2018 Scientific Article in Cell Cell 172, 409–422.e21 (2018)
Selenium utilization by GPX4 is required to prevent hydroperoxide-induced ferroptosis.
2018 Scientific Article in Gerontology Gerontology 64, 229–236 (2018)
Age-induced changes in white, brite, and brown adipose depots: A mini-review.
2018 Scientific Article in Critical reviews in clinical laboratory sciences Crit. Rev. Clin. Lab. Sci. 55, 21-32 (2018)
Serum and plasma amino acids as markers of prediabetes, insulin resistance, and incident diabetes.
2018 Scientific Article in Journal of Autoimmunity J. Autoimmun. 89, 63-74 (2018)
Allele-specific methylation of type 1 diabetes susceptibility genes.
2018 Scientific Article in Clinical Nutrition Clin. Nutr. 37, 2246-2251 (2018)
10 patients, 10 years - Long term follow-up of cardiovascular risk factors in Glut1 deficiency treated with ketogenic diet therapies: A prospective, multicenter case series.
2018 Review in Trends in Biochemical Sciences : TIBS Trends Biochem. Sci. 43, 1-4 (2018)
Immune responses - Transcriptional and post-transcriptional networks pass the baton.
2018 Scientific Article in Biomedical Chromatography Biomed. Chromatogr. 32:e4151 (2018)
Comprehensive analysis of nine monoamines and metabolites in small amounts of peripheral murine (C57Bl/6J) tissues.
2018 Scientific Article in Endocrine-Related Cancer Endocr. Relat. Cancer 25, 145-162 (2018)
Characterization of neuroendocrine tumors in heterozygous mutant MENX rats: A novel model of invasive medullary thyroid carcinoma.
2018 Scientific Article in Endocrinology Endocrinology 159, 400-413 (2018)
Dietary manipulations that induce ketosis activate the HPA axis in male rats and mice: A potential role for fibroblast growth factor-21.
2018 Scientific Article in Journal of Proteome Research J. Proteome Res. 17, 203-211 (2018)
Long-Term Stability of Human Plasma Metabolites during Storage at-80 degrees C.
2018 Scientific Article in Journal of Autoimmunity J. Autoimmun. 86, 93-103 (2018)
Gestational respiratory infections interacting with offspring HLA and CTLA-4 modifies incident beta-cell autoantibodies.
2018 Scientific Article in Mitochondrion Mitochondrion, DOI: 10.1016/j.mito.2017.08.015 (2018)
Mitochondrial adaptation in steatotic mice.
2018 Scientific Article in Journal of Investigative Dermatology, The J. Invest. Dermatol. 138, 141-149 (2018)
MSX1-induced neural crest-like reprogramming promotes melanoma progression.
2018 Scientific Article in International Journal of Obesity Int. J. Obes. 42, 507-517 (2018)
A history of obesity leaves an inflammatory fingerprint in liver and adipose tissue.
2018 Scientific Article in Journal of Investigative Dermatology, The J. Invest. Dermatol. 138, 179-188 (2018)
The role of Fibroblast growth factor binding protein 1 in skin carcinogenesis and inflammation.
2018 Scientific Article in Wiener medizinische Wochenschrift Wien. Med. Wochenschr. 168, 415–422 (2018)
Welche Patienten aus der Routinebetreuung verwenden das neue Insulin-Analogon Glargin U300 im Vergleich zu Patienten mit Glargin U100? Eine multizentrische Analyse von 14.123 Patienten mit Insulin Glargin aus den Diabetesregistern DPV und DIVE.
2018 Scientific Article in Journal of Breath Research J. Breath Res. 12:017102 (2018)
A systemic view on the distribution of diet-derived methanol and hepatic acetone in mice.
2018 Scientific Article in Pediatric Diabetes Pediatr. Diabetes 19, 277-283 (2018)
Prediction of type 1 diabetes using a genetic risk model in the Diabetes Autoimmunity Study in the Young.
In: Nutrition and Health. 2017. 67-78 ( ; Part F3933)
Maternal insulin sensitivity and fetal brain activity.
2017 Scientific Article in Bio-Protocol Bio Protoc. 7:e2521 (2017)
An ex vivo perifusion method for quantitative determination of neuropeptide release from mouse hypothalamic explants.
2017 Scientific Article in Diabetes Aktuell Diabetes akt. 15, 113-116 (2017)
Einfluss der Fettleber auf den Glukosestoffwechsel nicht unterschätzen. Neue Ansätze für die Diagnose und Behandlung.
2017 Scientific Article in Diabetes Aktuell Diabetes akt. 15, 121-122 (2017)
Wenn Sportintervention nicht zum Erfolg führt. Bedeutung der „richtigen“ Intervention.
2017 Scientific Article in European Journal of Endocrinology Eur. J. Endocrinol. 176, 123-132 (2017)
Acute administration of acyl, but not desacyl ghrelin, decreases blood pressure in healthy humans.
München, Technische Universität, Fakultät für Medizin, Diss., 2017, 88 S.
The role of mitochondrial fission protein Drp1 in pancreatic islets and beta cells.
Peter Lang GmbH, 2017. 359 Seiten
Gesundheit – Vom (bio)technologischen, (eigen)verantwortlichen, fairen und realistischen Umgang.
2017 Meeting abstract in Sleep Medicine Sleep Med. 40, E290-E291 (2017)
Circadian locomotor activity in meis1 knock-out mice.
2017 Meeting abstract in Acta clinica Belgica Acta Clin. Belg. 72, 16-17 (2017)
Long-term management of resistant acromegaly with pasireotide LAR in 2 cases with a familial AIP mutation.
München, Technische Universität, Fakultät für Medizin, Diss., 2017, 86 S.
Energy deprivation induces a specific secretome in skeletal muscle.
2017 Meeting abstract in Molecular Biology of the Cell Mol. Biol. Cell 28 (2017)
Proteomics identifies organelle specific phosphorylation and reveals major subcellular reorganization in the progression of NAFLD.
2017 Meeting abstract in European Journal of Immunology Eur. J. Immunol. 47, 186-186 (2017)
Linking TNF receptor signaling in virus-infected hepatocytes to cell death for immune control of liver infection.
2017 Diabetes Diabetes 66, e10-e11 (2017)
Response to comment on Rodriguez-Calvo et al. Increase in pancreatic proinsulin and preservation of β-cell mass in autoantibody-positive donors prior to type 1 diabetes onset. Diabetes 2017;66:1334–1345.
2017 Scientific Article in Pediatrics Pediatrics 139:e20162848 (2017)
Psychological manifestations of celiac disease autoimmunity in young children.
2017 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 103, 972-982 (2017)
Patterns of plasma glucagon dynamics do not match metabolic phenotypes in young women.
2017 Scientific Article in Lancet Diabetes and Endocrinology Lancet Diabet. Endocrinol. 5, 864-876 (2017)
Efficacy and safety of dapagliflozin in patients with inadequately controlled type 1 diabetes (DEPICT-1): 24 week results from a multicentre, double-blind, phase 3, randomised controlled trial.
2017 Nature Nature 551, 398 (2017)
Corrigendum: High-throughput discovery of novel developmental phenotypes.
2017 Scientific Article in Neonatology Neonatology 112, 246-250 (2017)
Reticulocyte haemoglobin content declines more markedly in preterm than in term infants in the first days after birth.
2017 Scientific Article in Biochemical Journal / Reviews Biochem. J. 474, 983-1001 (2017)
GFAT1 phosphorylation by AMPK promotes VEGF-induced angiogenesis.
2017 Scientific Article in Thrombosis and Haemostasis Thromb. Haemost. 117, 2369-2375 (2017)
Diagnostic accuracy of a novel chromogenic direct thrombin inhibitor assay: Clinical experiences for dabigatran monitoring.
2017 Scientific Article in Clinical & Experimental Immunology Clin. Exp. Immunol., DOI: 10.1111/cei.13059 (2017)
Granulocytic myeloid-derived suppressor cells (GR-MDSC) accumulate in cord blood of preterm infants and remain elevated during the neonatal period.
2017 Scientific Article in American Journal of Physiology - Endocrinology and Metabolism Am. J. Physiol. Endocrinol. Metab. 314, E266-E273 (2017)
The hepatokines fetuin-A and fetuin-B are upregulated in the state of hepatic steatosis and may differently impact on glucose homeostasis in humans.
2017 Scientific Article in Scientific Reports Sci. Rep. 7:40627 (2017)
Soluble urokinase receptor (suPAR) predicts microalbuminuria in patients at risk for type 2 diabetes mellitus.
2017 Scientific Article in Data in Brief Data Brief 15, 163-169 (2017)
Data on chow, liver tissue and mitochondrial fatty acid compositions as well as mitochondrial proteome changes after feeding mice a western diet for 6-24 weeks.
2017 Scientific Article in Cold Spring Harbor Perspectives in Medicine Cold Spring Harbor Perspect. Med. 7:a029793 (2017)
Skeletal muscle as an endocrine organ: The role of myokines in exercise adaptations.
2017 Editorial in Molecular Metabolism Mol. Metab. 6, VI-VI (2017)
Islet biology.
2017 Review in Kidney & Blood Pressure Research Kidney Blood Press. Res. 42, 749-760 (2017)
Eryptosis - the neglected cause of anemia in end stage renal disease.
2017 Review in International Journal of Molecular Sciences Int. J. Mol. Sci. 18:2578 (2017)
Long non-coding RNAs in metabolic organs and energy homeostasis.
2017 Editorial in Geburtshilfe und Frauenheilkunde Geburtsh. u. Frauenheilk. 77, 1151-1153 (2017)
New study on the prevention of type-1-diabetes.
2017 Scientific Article in JAMA Pediatrics JAMA Pediatr. 171, 1217-1225 (2017)
Association between early-life antibiotic use and the risk of islet or celiac disease autoimmunity.
2017 Scientific Article in Nature Genetics Nat. Genet. 49, 1722–1730 (2017)
Exome chip meta-analysis identifies novel loci and East Asian-specific coding variants that contribute to lipid levels and coronary artery disease.
2017 Scientific Article in Immunity Immunity 47, 1067-1082.e12 (2017)
Roquin suppresses the PI3K-mTOR signaling pathway to inhibit T helper cell differentiation and conversion of treg to Tfr cells.
2017 Scientific Article in Frontiers in Physiology Front. Physiol. 8:968 (2017)
Comparative analysis of muscle hypertrophy models reveals divergent gene transcription profiles and points to translational regulation of muscle growth through increased mTOR signaling.
2017 Scientific Article in Clinical Immunology Clin. Immunol. 188, 23-30 (2017)
GM-CSF producing autoreactive CD4(+) T cells in type 1 diabetes.
2017 Scientific Article in Nature Communications Nat. Commun. 8:1984 (2017)
Auditory closed-loop stimulation of EEG slow oscillations strengthens sleep and signs of its immune-supportive function.
2017 Scientific Article in Scientific Data Sci. Data 4:170179 (2017)
Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.
2017 Scientific Article in Nature Immunology Nat. Immunol. 19, 130–140 (2017)
Oxeiptosis, a ROS-induced caspase-independent apoptosis-like cell-death pathway.
2017 Scientific Article in Journal of Visualized Experiments J. Vis. Exp. 2017:e56538 (2017)
Analysis of immune cells in single sciatic nerves and dorsal root ganglion from a single mouse using flow cytometry.
2017 Scientific Article in Proceedings of the National Academy of Sciences of the United States of America Proc. Natl. Acad. Sci. U.S.A. 114, E11323-E11332 (2017)
Noncanonical thyroid hormone signaling mediates cardiometabolic effects in vivo.
2017 Scientific Article in Nature Genetics Nat. Genet. 49, 1758-1766 (2017)
Exome-wide association study of plasma lipids in >300,000 individuals.
2017 Scientific Article in Molecular Metabolism Mol. Metab. 8, 158-166:doi:10.1016/j.molmet.2017.11.013 (2017)
Androgen receptor overexpression in prostate cancer in type 2 diabetes.
2017 Meeting abstract in Free Radical Biology and Medicine Free Radical Biol. Med. 112, 24-24 (2017)
Selenium utilization by GPX4 was an evolutionary requirement to prevent hydroperoxide-induced ferroptosis.
2017 Scientific Article in Journal of Proteome Research J. Proteome Res. 17, 618-634 (2017)
Proteomic landscape of patient-derived CD4+T cells in recent-onset type 1 diabetes.
2017 Meeting abstract in Medicine & Science in Sports & Exercise Med. Sci. Sports Exerc. 49, 702-702 (2017)
Role of neuronal fractalkine in reducing diet-induced hypothalamic inflammation.
2017 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 103, 253-262 (2017)
Dose-dependent effects of intranasal insulin on resting-state brain activity.
2017 Scientific Article in Molecular Metabolism Mol. Metab. 7, 155-160 (2017)
Deficiency of leptin receptor in myeloid cells disrupts hypothalamic metabolic circuits and causes body weight increase.
2017 Scientific Article in Diabetic Medicine Diabetic Med. 34, 1792-1794 (2017)
Insulin secretory defect in familial partial lipodystrophy Type 2 and successful long-term treatment with a glucagon-like peptide 1 receptor agonist.
2017 Scientific Article in Pediatric Diabetes Pediatr. Diabetes 18, 794-802 (2017)
Residual beta-cell function in diabetes children followed and diagnosed in the TEDDY study compared to community controls.
2017 Scientific Article in Diabetologia Diabetologia 60, 2341-2351 (2017)
Non-alcoholic fatty liver disease and impaired proinsulin conversion as newly identified predictors of the long-term non-response to a lifestyle intervention for diabetes prevention: Results from the TULIP study.
2017 Scientific Article in Bioorganic and Medicinal Chemistry Bioorg. Med. Chem. 26, 2873-2881 (2017)
Optimization of peptide-based polyagonists for treatment of diabetes and obesity.
2017 Scientific Article in Nature Communications Nat. Commun. 8:1725 (2017)
Stress-responsive FKBP51 regulates AKT2-AS160 signaling and metabolic function.
2017 Scientific Article in Kidney & Blood Pressure Research Kidney Blood Press. Res. 42, 598-607 (2017)
Dynamics of glucose metabolism after Kkdney transplantation.
2017 Scientific Article in Frontiers in Physiology Front. Physiol. 8:909 (2017)
Mitochondrial proton leak compensates for reduced oxidative power during frequent hypothermic events in a protoendothermic mammal, Echinops telfairi.
2017 Scientific Article in Scientific Reports Sci. Rep. 7:15486 (2017)
Excessive fuel availability amplifies the FTO-mediated obesity risk: Results from the TUEF and Whitehall II studies.
2017 Scientific Article in Hormone and Metabolic Research Horm. Metab. Res. 49, 892-898 (2017)
Thymus growth and fetal immune responses in diabetic pregnancies.
2017 Scientific Article in Data in Brief Data Brief 14, 653-658 (2017)
Data on the effects of eIF6 downmodulation on the proportions of innate and adaptive immune system cell subpopulations and on thymocyte maturation.
2017 Meeting abstract in Annals of the Rheumatic Diseases : ARD online Ann. Rheum. Dis. 76, 500-500 (2017)
Cardiac, pulmonary and periodontal disease as comorbidities in TNF-driven models of chronic polyarthritis.
2017 Scientific Article in Neuron Neuron 96, 713-715 (2017)
A synaptic basis for GLP-1 action in the brain.
2017 Scientific Article in Hormone and Metabolic Research Horm. Metab. Res. 50, 44-49 (2017)
Screening for type 1 diabetes risk in newborns: The Freder1k pilot study in Saxony.
2017 Scientific Article in Cell Reports Cell Rep. 21, 1507-1520 (2017)
The role of Eif6 in skeletal muscle homeostasis revealed by endurance training co-expression networks.
2017 Scientific Article in Journal of the American Society of Nephrology J. Am. Soc. Nephrol. 28, 3182-3189 (2017)
Farnesoid X receptor agonism protects against diabetic tubulopathy: Potential add-on therapy for diabetic nephropathy.
2017 Scientific Article in Journal of Clinical Investigation J. Clin. Invest. 127, 4148-4162 (2017)
Adipocyte cannabinoid receptor CB1 regulates energy homeostasis and alternatively activated macrophages.
2017 Scientific Article in Scientific Reports Sci. Rep. 7:15453 (2017)
Female mice lacking Pald1 exhibit endothelial cell apoptosis and emphysema.
2017 Scientific Article in PLoS ONE PLoS ONE 12:e0187192 (2017)
Open housing drives the expression of immune response genes in the nasal mucosa, but not the olfactory bulb.
2017 Scientific Article in Nucleic Acids Research Nucleic Acids Res. 45, 10595-10613 (2017)
Homeostatic nuclear RAGE-ATM interaction is essential for efficient DNA repair.
2017 Scientific Article in Diabetologia Diabetologia 60, 2240-2251 (2017)
Metabolic crosstalk between fatty pancreas and fatty liver: Effects on local inflammation and insulin secretion.
2017 Review in Clinical physiology and functional imaging Clin. Physiol. & Func. Im. 37, 558-566 (2017)
Intramyocellular lipids and their dynamics assessed by 1H magnetic resonance spectroscopy.
2017 Scientific Article in Diabetes Diabetes 66, 2822-2829 (2017)
Tbx15 defines a glycolytic subpopulation and white adipocyte heterogeneity.
2017 Scientific Article in Cell Metabolism Cell Metab. 26, 1–14.e1–e5 (2017)
Acetyl-CoA carboxylase 1-dependent protein acetylation controls breast cancer metastasis and recurrence.
München, Ludwig-Maximilians-Universität, Fakultät für Mathematik, Informatik und Statistik, Diss., 2017, 166 S.
Flexible Bayesian joint models for longitudinal biomarkers and time-to-event outcomes with applications to type 1 diabetes research.
2017 Diabetologia Diabetologia 61, 254-254 (2017)
Correction to: Respiratory infections are temporally associated with initiation of type 1 diabetes autoimmunity: The TEDDY study.
2017 Scientific Article in BJOG BJOG 124, 1891-1898 (2017)
Gestational diabetes alters the fetal heart rate variability during an oral glucose tolerance test: a fetal magnetocardiography study.
2017 Scientific Article in Kidney International Kidney Int. 93, 159-172 (2017)
Aprotinin prevents proteolytic epithelial sodium channel (ENaC) activation and volume retention in nephrotic syndrome.
2017 Meeting abstract in Annals of the Rheumatic Diseases : ARD online Ann. Rheum. Dis. 76, A49-A49 (2017)
TNF delta ARE/+: A multimorbidity model of spondyorthropathies.
2017 Review in Hormone molecular biology and clinical investigation Horm. Mol. Biol. Clin. Investig. 31:0043 (2017)
Endocrine and autocrine/paracrine modulators of brown adipose tissue mass and activity as novel therapeutic strategies against obesity and type 2 diabetes.
2017 Meeting abstract in Diabetologia Diabetologia 60, S507-S508 (2017)
Loss of glyoxalase 1 in various mammalian cells is associated with an increased resistance against environmental stressors.
2017 Scientific Article in Journal of Food Composition and Analysis J. Food Compos. Anal. 63, 79-88 (2017)
Development of a harmonized food grouping system for between-country comparisons in the TEDDY Study.
2017 Meeting abstract in Diabetologia Diabetologia 60, S565-S565 (2017)
Complex interplay between androgen, estrogen and insulin receptor gene expression in prostate cancer depending on diabetes status.
2017 Meeting abstract in Diabetologia Diabetologia 60, S483-S483 (2017)
The 'fatty kidney': Crosstalk of renal sinus fat with glomerular cells under the influence of the hepatokine fetuin-A.
2017 Meeting abstract in Diabetologia Diabetologia 60, S44-S44 (2017)
Apelinergic system in placenta of women with gestational diabetes.
2017 Scientific Article in Genesis : The Journal of Genetics and Development Genesis 55:e23073 (2017)
A novel Cre-inducible knock-in ARL13B-tRFP fusion cilium reporter.
2017 Scientific Article in Diabetologia Diabetologia 61, 193–202 (2017)
Pandemrix® vaccination is not associated with increased risk of islet autoimmunity or type 1 diabetes in the TEDDY study children.
2017 Scientific Article in Neuroscience Neuroscience, DOI: 10.1016/j.neuroscience.2017.09.023 (2017)
The quest for more research on painful diabetic neuropathy.
2017 Scientific Article in Molecular Metabolism Mol. Metab. 6, 1254-1263 (2017)
Elevated hepatic DPP4 activity promotes insulin resistance and non-alcoholic fatty liver disease.
2017 Scientific Article in Diabetologie, Die Diabetologie 13, 505–513 (2017)
Inkretinbasierte Medikamente zur Diabetes- und Adipositastherapie. Entwicklungsperspektiven.
2017 Scientific Article in Science Advances Sci. Adv. 3:e1602878 (2017)
Inactivation of thermogenic UCP1 as a historical contingency in multiple placental mammal clades.
2017 Scientific Article in American Journal of Psychiatry, The Am. J. Psychiatry 174, 850-858 (2017)
Significant locus and metabolic genetic correlations revealed in genome-wide association study of anorexia nervosa.
2017 Scientific Article in Cell Death and Differentiation Cell Death Differ. 24, 1948-1962 (2017)
High mobility group A1 protein modulates autophagy in cancer cells.
2017 Scientific Article in Pediatrics Pediatrics 140, DOI: 10.1542/peds.2017-1305 (2017)
Co-occurrence of type 1 diabetes and celiac disease autoimmunity.
2017 Scientific Article in Nature Communications Nat. Commun. 8:886 (2017)
A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction.
2017 Scientific Article in Nucleic Acids Research Nucleic Acids Res. 45, 11121-11130 (2017)
DNA residence time is a regulatory factor of transcription repression.
2017 Scientific Article in Nature Structural & Molecular Biology Nat. Struct. Mol. Biol. 24, 902-910 (2017)
MacroH2A1.1 regulates mitochondrial respiration by limiting nucleas NAD+ consumption.
2017 Review in Cell Metabolism Cell Metab. 26, 585-587 (2017)
Dietary carbohydrates impair healthspan and promote mortality.
2017 Scientific Article in Behavioural Brain Research Behav. Brain Res. 352, 187-196 (2017)
Understanding gene functions and disease mechanisms: Phenotyping pipelines in the German Mouse Clinic.
2017 Scientific Article in Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet. 126, 141-147 (2017)
Purification and Characterization of the Soluble form of the Receptor for Advanced Glycation End-Products (sRAGE): A Novel Fast, Economical and Convenient Method.
2017 Scientific Article in Cell Reports Cell Rep. 20, 3034-3042 (2017)
Lipoprotein lipase maintains microglial innate immunity in obesity.
2017 Scientific Article in Obesity Obesity 25, 1647-1649 (2017)
Emerging poly-agonists for obesity and type 2 diabetes.
2017 Scientific Article in Frontiers in Physiology Front. Physiol. 8:704 (2017)
Comparison of mitochondrial reactive oxygen species production of ectothermic and endothermic fish muscle.
2017 Scientific Article in Development / Company of Biologists Development 144, 3917-3931 (2017)
The E2A splice variant E47 regulates the differentiation of projection neurons via p57(KIP2) during cortical development.
2017 Scientific Article in Diabetologia Diabetologia 61, 117-129 (2017)
Metabolite ratios as potential biomarkers for type 2 diabetes: A DIRECT study.
2017 Scientific Article in Drug discovery today Drug Discov. Today, DOI: 10.1016/j.ddmod.2017.08.002 (2017)
Genome wide conditional mouse knockout resources.
2017 Scientific Article in Cell Metabolism Cell Metab. 26, 620-632.e6 (2017)
Molecular integration of incretin and glucocorticoid action reverses immunometabolic dysfunction and obesity.
2017 Scientific Article in Scientific Reports Sci. Rep. 7:11992 (2017)
Netrin-1 derived from the ventricular zone, but not the floor plate, directs hindbrain commissural axons to the ventral midline.
2017 Meeting abstract in Journal of Investigative Dermatology, The J. Invest. Dermatol. 137, S311-S311 (2017)
Blocking negative effects of senescence in human skin fibroblasts with a plant extract.
2017 Meeting abstract in Journal of Investigative Dermatology, The J. Invest. Dermatol. 137, S250-S250 (2017)
Senescent human fibroblasts selectively secrete miRNAs in extracellular vesicles and modulate keratinocyte functionality during skin aging.
2017 Scientific Article in European Journal of Clinical Nutrition Eur. J. Clin. Nutr. 71, 1449-1454 (2017)
Vitamin D and probiotics supplement use in young children with genetic risk for type 1 diabetes.
2017 Scientific Article in Lancet Diabetes and Endocrinology Lancet Diabet. Endocrinol. 6, 249-258 (2017)
Metabolically healthy obesity: The low-hanging fruit in obesity treatment?
2017 Scientific Article in PLoS ONE PLoS ONE 12:e0183488 (2017)
Dual specificity phosphatase 6 deficiency is associated with impaired systemic glucose tolerance and reversible weight retardation in mice.
2017 Meeting abstract in Allergy Allergy 72, 40-40 (2017)
Interference into JAK/stat signalling-a concept for improved allergen-specific immunotherapy?
2017 Scientific Article in Diabetes Diabetes 66, 3122-3129 (2017)
The influence of type 1 diabetes genetic susceptibility regions, age, sex, and family history to the progression from multiple autoantibodies to type 1 diabetes: A TEDDY Study Report.
2017 Scientific Article in Deutsche Medizinische Wochenschrift - DMW Dtsch. Med. Wochenschr. 142, e131-e139 (2017)
Umsetzung der Nationalen VersorgungsLeitlinie (NVL) zur Therapie des Diabetes mellitus Typ 2 in diabetologischen Schwerpunktpraxen.
2017 Scientific Article in Pediatric obesity Pediatr. Obes. 12, 1, 125-129 (2017)
The relationship between breast milk leptin and adiponectin with child body composition from 3 to 5 years: A follow-up study.
2017 Scientific Article in Oncogene Oncogene 36, 4987-4996 (2017)
Insulin resistance in vascular endothelial cells promotes intestinal tumour formation.
2017 Scientific Article in Acta Diabetologica Acta Diabetol. 54, 1009–1017 (2017)
Joint modeling of longitudinal autoantibody patterns and progression to type 1 diabetes: Results from the TEDDY study.
2017 Scientific Article in EMBO Reports EMBO Rep. 18, 2015-2029 (2017)
The BEACH protein LRBA is required for hair bundle maintenance in cochlear hair cells and for hearing.
2017 Scientific Article in PLoS Medicine PLoS Med. 14:e1002383 (2017)
Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.
2017 Scientific Article in Cell Metabolism Cell Metab. 26, 475-492.e7 (2017)
A Stat6/Pten axis links regulatory T cells with adipose tissue function.
2017 Scientific Article in Diabetes Care Diabetes Care 40, 1167-1172 (2017)
My child is islet autoantibody positive: Impact on parental anxiety.
2017 Scientific Article in Diabetes Care Diabetes Care 40, 1194-1202 (2017)
Genetic and environmental interactions modify the risk of diabetes-related autoimmunity by 6 years of age: The TEDDY Study.
2017 Letter to the Editor in Diabetes Diabetes 66, e10-e11 (2017)
Response to comment on Rodriguez-Calvo et al. Increase in pancreatic proinsulin and preservation of β-cell mass in autoantibody-positive donors prior to type 1 diabetes onset. diabetes 2017;66:1334-1345.
2017 Editorial in Cell Stem Cell Cell Stem Cell 21, 153-155 (2017)
Engineering skin with skinny genes.
2017 Editorial in Cell Metabolism Cell Metab. 26, 289-291 (2017)
Once blind, now we see GLP-1 molecular action.
2017 Scientific Article in Redox Biology Redox Biol. 13, 674-686 (2017)
Hormesis enables cells to handle accumulating toxic metabolites during increased energy flux.
2017 Scientific Article in Molecular Cell Mol. Cell 67, 711-723.e7 (2017)
Systematic identification of MCU modulators by orthogonal Iiterspecies chemical screening.
2017 Scientific Article in Journal of Biomedical Science J. Biomed. Sci. 24:57 (2017)
Standardized, systemic phenotypic analysis reveals kidney dysfunction as main alteration of Kctd1I27N mutant mice.
2017 Scientific Article in Journal of Steroid Biochemistry and Molecular Biology, The J. Steroid Biochem. Mol. Biol. 174, 114-119 (2017)
Immediate reduction of serum citrulline but no change of steroid profile after initiation of metformin in individuals with type 2 diabetes.
Scientific Article in Endocrine Development In: (10th ESPE Advanced Seminar in Developmental Endocrinology, 10 June 2016, Ulm). 2017. 165-182 (Endocr. Dev. ; 32)
Treatment of diabetes and obesity by rationally designed peptide agonists functioning at multiple metabolic receptors.
2017 Letter to the Editor in Journal of Biological Chemistry, The J. Biol. Chem. 292, 12784-12785 (2017)
Reply to Richarme: Evidence against a role of DJ-1 in methylglyoxal detoxification.
2017 Scientific Article in Diabetologia Diabetologia 60, 1931-1940 (2017)
Respiratory infections are temporally associated with initiation of type 1 diabetes autoimmunity: The TEDDY study.
2017 Review in Development / Company of Biologists Development 144, 2873-2888 (2017)
Cellular and molecular mechanisms coordinating pancreas development.
2017 Scientific Article in Biometrical Journal Biom. J. 59, 1144-1165 (2017)
Flexible Bayesian additive joint models with an application to type 1 diabetes research.
2017 Scientific Article in BMC Ophthalmology BMC Ophthalmol. 17:139 (2017)
Patients' preferences for involvement in the decision-making process for treating diabetic retinopathy.
2017 Scientific Article in Respiratory Research Respir. Res. 18:152 (2017)
Transcriptomic analysis comparing mouse strains with extreme total lung capacities identifies novel candidate genes for pulmonary function.
2017 Scientific Article in Thorax Thorax 72, 1007-1020 (2017)
Pulmonary CCR2+CD4+ T cells are immune regulatory and attenuate lung fibrosis development.
2017 Scientific Article in Stroke Stroke 48, 2457-2463 (2017)
Emergency coagulation assessment during treatment with direct oral anticoagulants: Limitations and solutions.
2017 Scientific Article in JCI insight JCI insight 2:e92970 (2017)
Integration of homeostatic signaling and food reward processing in the human brain.
2017 Other: Opinion in Molecular Metabolism Mol. Metab. 6, 1079-1080 (2017)
Anti-hypertensive treatment in pregnancy impacts offspring growth and metabolism: Q&A.
2017 Scientific Article in NMR in Biomedicine NMR Biomed. 30:e3744 (2017)
Intra- and interindividual variability of fatty acid unsaturation in six different human adipose tissue compartments assessed by 1H-MRS in vivo at 3 T.
2017 Scientific Article in Chemical senses Chem. Senses 42, 585-592 (2017)
Oil perception-detection thresholds for varying fatty stimuli and inter-individual differences.
2017 Scientific Article in Scientific Reports Sci. Rep. 7:8888 (2017)
Extracellular calcium modulates brown adipocyte differentiation and identity.
2017 Scientific Article in Cell Metabolism Cell Metab. 26, 343-352.e2 (2017)
The sustained effects of a dual GIP/GLP-1 receptor agonist, NNC0090-2746, in patients with type 2 diabetes.
2017 Scientific Article in Molecular Metabolism Mol. Metab. 6, 974-990 (2017)
Systematic single-cell analysis provides new insights into heterogeneity and plasticity of the pancreas.
2017 Scientific Article in Diabetes Diabetes 66, 2296-2309 (2017)
A genome-wide association study of IVGTT-based measures of first-phase insulin secretion refines the underlying physiology of type 2 diabetes variants.
2017 Review in Frontiers in Neuroscience Front. Neurosci. 11:369 (2017)
Circadian metabolomics in time and space.
2017 Review in Endocrine Reviews Endocr. Rev. 38, 468-488 (2017)
Fibroblast growth factor 21 – metabolic role in mice and men.
2017 Scientific Article in Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet. 126, 123-129 (2017)
Prevalence and distribution of diabetes mellitus in a maximum care hospital: Urgent need for HbA(1c)-screening.
2017 Scientific Article in Current Opinion in Systems Biology Curr. Opin. Syst. Biol. 4, 97-104 (2017)
Big data in large-scale systemic mouse phenotyping.
2017 Scientific Article in Cell Reports Cell Rep. 20, 1422-1434 (2017)
A hepatic GAbp-AMPK axis links inflammatory signaling to systemic vascular damage.
2017 Review in Frontiers in Endocrinology Front. Endocrin. 8:197 (2017)
Hypothalamic inflammation and energy balance disruptions: Spotlight on chemokines.
2017 Scientific Article in American Journal of Epidemiology Am. J. Epidemiol. 186, 1277-1280 (2017)
Infections in early Life and development of celiac disease.
2017 Scientific Article in PLoS ONE PLoS ONE 12:e0181880 (2017)
DPP4 gene variation affects GLP-1 secretion, insulin secretion, and glucose tolerance in humans with high body adiposity.
2017 Scientific Article in Cell Metabolism Cell Metab. 26, 437-446.e5 (2017)
Long-term cold adaptation does not require FGF21 or UCP1.
2017 Scientific Article in Cell Metabolism Cell Metab. 26, 292-300 (2017)
Causes, characteristics, and consequences of metabolically unhealthy normal weight in humans.
2017 Scientific Article in Endocrine-Related Cancer Endocr. Relat. Cancer 24, T161-T177 (2017)
Animal models of MEN1.
2017 Scientific Article in Journal of Pediatric Gastroenterology and Nutrition J. Pediatr. Gastroenterol. Nutr. 66, 417-424 (2017)
Cesarean section on the risk of celiac disease in the offspring: The Teddy Study.
2017 Scientific Article in Diabetes Aktuell Diabetes akt. 15, 109-111 (2017)
Das Gehirn als Schaltzentrale des Stoffwechsels.
2017 Review in Diabetologia Diabetologia 60, 1851–1861 (2017)
GLP-1/glucagon receptor co-agonism for treatment of obesity.
2017 Other: Opinion in Proceedings of the National Academy of Sciences of the United States of America Proc. Natl. Acad. Sci. U.S.A. 114, 7744-7746 (2017)
Uncoupling protein 1 controls reactive oxygen species in brown adipose tissue.
2017 Scientific Article in Nature Communications Nat. Commun. 8:155 (2017)
Every-other-day feeding extends lifespan but fails to delay many symptoms of aging in mice.
2017 Scientific Article in Diabetes Aktuell Diabetes akt. 15, 104-107 (2017)
Ernährungsgewohnheiten schlagen sich im Erbgut nieder.
2017 Scientific Article in Molecular Metabolism Mol. Metab. 6, 873-881 (2017)
Repletion of branched chain amino acids reverses mTORC1 signaling but not improved metabolism during dietary protein dilution.
2017 Scientific Article in Pediatric Research Pediatr. Res. 81, 745-751 (2017)
Cord blood and child plasma adiponectin levels in relation to childhood obesity risk and fat distribution up to 5 y.
2017 Editorial in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 12, 184-185 (2017)
Eine seltene Ursache für eine hyperinsulinämische Hypoglykämie.
2017 Letter to the Editor in Nature Reviews - Endocrinology Nat. Rev. Endocrinol. 13, 492-492 (2017)
β-Cell mass versus function in type 1 diabetes mellitus: truth or dare?
2017 Scientific Article in Appetite Appetite 117, 255-262 (2017)
Visual food cues decrease postprandial glucose concentrations in lean and obese men without affecting food intake and related endocrine parameters.
2017 Scientific Article in Diabetes Diabetes 66, 2555-2563 (2017)
Disruption of lipid uptake in astroglia exacerbates diet induced obesity.
2017 Scientific Article in Diabetes & metabolism Diabetes Metab. 43, 229-239 (2017)
An extended fatty liver index to predict non-alcoholic fatty liver disease.
2017 Review in Current Medicinal Chemistry Curr. Med. Chem. 24, 1827-1852 (2017)
Divergent roles of IRS (Insulin receptor substrate) 1 and 2 in liver and skeletal muscle.
2017 Scientific Article in Molecular Metabolism Mol. Metab. 6, 1304-1312 (2017)
Point mutation of Ffar1 abrogates fatty acid-dependent insulin secretion, but protects against HFD-induced glucose intolerance.
2017 Scientific Article in Molecular Metabolism Mol. Metab. 6, 1226-1239 (2017)
Activated macrophages control human adipocyte mitochondrial bioenergetics via secreted factors.
2017 Scientific Article in Journal of Nuclear Medicine J. Nucl. Med. 58, 1100-1103 (2017)
Dissociation between brown adipose tissue 18F-FDG uptake and thermogenesis in uncoupling protein 1 deficient mice.
2017 Scientific Article in PLoS Biology PLoS Biol. 15:e2001414 (2017)
Identifiers for the 21st century: How to design, provision, and reuse persistent identifiers to maximize utility and impact of life science data.
2017 Scientific Article in Developmental and comparative immunology Dev. Comp. Immunol. 77, 69-76 (2017)
High levels of eukaryotic Initiation Factor 6 (eIF6) are required for immune system homeostasis and for steering the glycolytic flux of TCR-stimulated CD4+ T cells in both mice and humans.
2017 Review in EMBO Journal, The EMBO J. 36, 1999-2017 (2017)
Adipose tissue: Between the extremes.
2017 Scientific Article in Nature Neuroscience Nat. Neurosci. 20, 1096-1103 (2017)
Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule 1.
2017 Scientific Article in Nature Communications Nat. Commun. 8:15475 (2017)
Prevalence of sexual dimorphism in mammalian phenotypic traits.
2017 Scientific Article in Nature Genetics Nat. Genet. 49, 1231-1238 (2017)
Disease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium.
2017 Scientific Article in Molecular Metabolism Mol. Metab. 6, 1286-1295 (2017)
Angiopoietin-like protein 4 is an exercise-induced hepatokine in humans, regulated by glucagon and cAMP.
2017 Scientific Article in Molecular Metabolism Mol. Metab. 6, 931-940 (2017)
The Munich MIDY Pig Biobank - A unique resource for studying organ crosstalk in diabetes.
2017 Scientific Article in Water Research Water Res. 122, 290-298 (2017)
Iopromide exposure in Typha latifolia L.: Evaluation of uptake, translocation and different transformation mechanisms in planta.
2017 Scientific Article in Immunology Immunology 152, 402-413 (2017)
microRNA cluster 106a~363 is involved in T-Helper 17 (Th17) cell differentiation.
2017 Scientific Article in Current Protocols of Mouse Biology Curr. Protoc. Mouse Biol. 7, 88-99 (2017)
A Fast, Easy, and Customizable Eight-Color Flow Cytometric Method for Analysis of the Cellular Content of Bronchoalveolar Lavage Fluid in the Mouse.
2017 Scientific Article in Disease Models and Mechanisms Dis. Model. Mech. 10, 981-991 (2017)
Meis1 effects on motor phenotypes and the sensorimotor system in mice.
2017 Scientific Article in Journal of Theoretical Biology J. Theor. Biol. 430, 32-44 (2017)
Modeling coexistence of oscillation and Delta/Notch-mediated lateral inhibition in pancreas development and neurogenesis.
2017 Scientific Article in Kidney & Blood Pressure Research Kidney Blood Press. Res. 42, 257-266 (2017)
Routine monitoring of sodium and phosphorus removal in peritoneal dialysis (PD) patients treated with continuous ambulatory PD (CAPD), automated PD (APD) or combined CAPD plus APD.
2017 Scientific Article in Particle and Fibre Toxicology Part. Fibre Toxicol. 14:19 (2017)
Early pulmonary response is critical for extra-pulmonary carbon nanoparticle mediated effects: Comparison of inhalation versus intra-arterial infusion exposures in mice.
2017 Scientific Article in Obesity Obesity 25, 1435-1441 (2017)
Intake of energy and protein is associated with overweight risk at age 5.5 years: Results from the prospective TEDDY study.
2017 Scientific Article in Obesity Obesity 25, 1277-1283 (2017)
Genetic determination of body fat distribution and the attributive influence on metabolism.
2017 Scientific Article in Diabetes Diabetes 66, 1797-1806 (2017)
Hypothalamic and striatal insulin action suppresses endogenous glucose production and may stimulate glucose uptake during hyperinsulinemia in lean but not in overweight men.
2017 Scientific Article in Nature medicine Nat. Med. 23, 829-838 (2017)
Thermoneutral housing exacerbates nonalcoholic fatty liver disease in mice and allows for sex-independent disease modeling.
Diabetes In:. Alexandria: Amer Diabetes Assoc, 2017. 1766-1769 (Diabetes ; 66)
Single-molecule combinatorial therapeutics for treating obesity and diabetes.
2017 Scientific Article in Proceedings of the National Academy of Sciences of the United States of America Proc. Natl. Acad. Sci. U.S.A. 114, E5167-E5176 (2017)
Optogenetic control of mitochondrial metabolism and Ca2+ signaling by mitochondria-targeted opsins.
2017 Scientific Article in Molecular Metabolism Mol. Metab. 6, 897-908 (2017)
Dietary sugars, not lipids, drive hypothalamic inflammation.
2017 Meeting abstract in Haematologica - The Hematology Journal Haematologica 102, 333-333 (2017)
Lack of the ferroptosis inhibitor GPX4 in erythroid cells causes a block in reticulocyte maturation and a hypoxic signature with impaired hepcidin regulation.
2017 Acta Diabetologica Acta Diabetol. 54, 713-714 (2017)
Erratum to: A novel insulin sensitivity index particularly suitable to measure insulin sensitivity during gestation.
2017 Meeting abstract in Glia Glia 65, E511-E511 (2017)
Hypercaloric environment triggers chronic remodeling of the hypothalamic vasculature via astroglial HIF1 alpha and VEGF signaling.
2017 Meeting abstract in Glia Glia 65, E219-E219 (2017)
Astrocytic leptin and insulin signals interact to maintain systemic metabolic homeostasis.
2017 Meeting abstract in Glia Glia 65, E218-E218 (2017)
Hypothalamic astrocyte activity state determines systemic glucose metabolism in mice.
2017 Meeting abstract in Glia Glia 65, E217-E218 (2017)
Astrocytic UCP2 is required for hypothalamic response to metabolic challenges.
2017 Meeting abstract in Glia Poster: (2017)
Mitochondrial function in Pink1 deficient astrocytes.
2017 Meeting abstract in Glia Glia 65, E401-E401 (2017)
Proliferation and neural stem cell potential of diencephalic astrocytes revealed by genome-wide expression analysis is Smad4-dependent.
2017 Other: News Item in EMBO Reports EMBO Rep. 18, 1039-1040 (2017)
Let's burn whatever you have: Mitofusin 2 metabolically re-wires brown adipose tissue.
2017 Scientific Article in Clinical therapeutics Clin. Ther. 39, 1132-1144.e2 (2017)
Electrical muscle stimulation induces an increase of VEGFR2 on circulating hematopoietic stem cells in patients with diabetes.
2017 Scientific Article in Developmental psychobiology Dev. Psychobiol. 59, 658-667 (2017)
The feasibility of salivary sample collection in an international pediatric cohort: The the TEDDY study.
2017 Scientific Article in Molecular Neurobiology Mol. Neurobiol. 55, 4580–4595 (2017)
Fgf9Y162C mutation alters information processing and social memory in mice.
2017 Scientific Article in Psychopharmacology Psychopharmacology (Berl.) 234, 1923-1932 (2017)
Body and liver fat content and adipokines in schizophrenia: A magnetic resonance imaging and spectroscopy study.
2017 Scientific Article in International Immunology Int. Immunol. 29, 173-181 (2017)
Splicing in immune cells - mechanistic insights and emerging topics.
2017 Scientific Article in Diabetologie, Die Diabetologie 13, 244-247 (2017)
Mischformen und Überlappung des Typ-1- und des Typ-2-Diabetes. Limitationen individueller Therapieoptionen durch die bestehende Disease-Management-Programm-Systematik.
2017 Scientific Article in Scientific Reports Sci. Rep. 7:4023 (2017)
Acute loss of the hepatic endo-lysosomal system in vivo causes compensatory changes in iron homeostasis.
2017 Scientific Article in BMC Pediatrics BMC Pediatr. 17:127 (2017)
Analgesic antipyretic use among young children in the TEDDY study: No association with islet autoimmunity.
2017 Scientific Article in Journal of Physiology - Paris J. Physiol. 595, 4845-4855 (2017)
Mammalian target of rapamycin complex 2 regulates muscle glucose uptake during exercise in mice.
2017 Scientific Article in Nature Communications Nat. Commun. 8:15069 (2017)
Elevated levels of Bcl-3 inhibits Treg development and function resulting in spontaneous colitis.
2017 Scientific Article in PLoS ONE PLoS ONE 12:e0179128 (2017)
Physical fitness and plasma leptin in women with recent gestational diabetes.
2017 Scientific Article in Cell Reports Cell Rep. 19, 643-654 (2017)
Rapid genome-wide recruitment of RNA polymerase II drives transcription, splicing, and translation events during T cell responses.
2017 Scientific Article in Cellular Signalling Cell. Signal. 36, 91-97 (2017)
Sunitinib specifically augments glucose-induced insulin secretion.
2017 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 195 (2017)
2d cross-omics integrated enrichment analysis of human and mice COPD lungs reveal novel pathological mechanisms of disease progression.
2017 Scientific Article in Neurobiology of Aging Neurobiol. Aging 54, 170-174 (2017)
Intranasal insulin decreases circulating cortisol concentrations during early sleep in elderly humans.
2017 Scientific Article in eLife eLife 6:e21231 (2017)
Evolution of the hypoxia-sensitive cells involved in amniote respiratory reflexes.
2017 Review in International Journal of Molecular Sciences Int. J. Mol. Sci. 18:984 (2017)
Dicarbonyls and advanced glycation end-products in the development of diabetic complications and targets for intervention.
2017 Scientific Article in Scientific Reports Sci. Rep. 7:1627 (2017)
Intranasal insulin enhances brain functional connectivity mediating the relationship between adiposity and subjective feeling of hunger.
2017 Scientific Article in PLoS ONE PLoS ONE 12:e177148 (2017)
Common variation in the sodium/glucose cotransporter 2 gene SLC5A2 does neither affect fasting nor glucose-suppressed plasma glucagon concentrations.
2017 Review in International Journal of Molecular Sciences Int. J. Mol. Sci. 18:798 (2017)
Therapeutic potential of targeting the ghrelin pathway.
2017 Scientific Article in Molecular Metabolism Mol. Metab. 6, 524-534 (2017)
Foxa2 and Pdx1 cooperatively regulate postnatal maturation of pancreatic β-cells.
2017 Scientific Article in Theriogenology Theriogenology 96, 49-57 (2017)
Dry ice is a reliable substrate for the distribution of frozen mouse spermatozoa: A multi-centric study.
2017 Scientific Article in Clinical Gastroenterology and Hepatology Clin. Gastroenterol. Hepatol. 15, 694-702 (2017)
Factors that increase risk of celiac disease autoimmunity after a gastrointestinal infection in early life.
2017 Scientific Article in PLoS ONE PLoS ONE 12:e0177154 (2017)
Pancreatic fat content by magnetic resonance imaging in subjects with prediabetes, diabetes, and controls from a general population without cardiovascular disease.
2017 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 195 (2017)
Epigenetic histone-1 modulator Hmgn5 regulates cellular apoptosis In COPD pathogenesis.
2017 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 195 (2017)
Deficiency of immunoproteasome subunits increases alternative polarization of alveolar macrophages.
2017 Scientific Article in Proceedings of the National Academy of Sciences of the United States of America Proc. Natl. Acad. Sci. U.S.A. 114, 5265-5270 (2017)
Lsd1 prevents age-programed loss of beige adipocytes.
2017 Scientific Article in Journal of Neuroimmunology J. Neuroimmunol. 306, 76-82 (2017)
STZ causes depletion of immune cells in sciatic nerve and dorsal root ganglion in experimental diabetes.
2017 Scientific Article in Pharmacogenetics Pharmacogenet. Genomics 27, 135-142 (2017)
Influence of common polymorphisms in the SLC5A2 gene on metabolic traits in subjects at increased risk of diabetes and on response to empagliflozin treatment in patients with diabetes.
2017 Scientific Article in Therapeutic drug monitoring Ther. Drug Monit. 39, 102-108 (2017)
Therapeutic drug monitoring of everolimus: Comparability of concentrations determined by 2 immunoassays and a liquid chromatography tandem mass spectrometry method.
2017 Scientific Article in Journal of Cancer Research and Clinical Oncology J. Cancer Res. Clin. Oncol. 143, 759-771 (2017)
Uric acid as a novel biomarker for bone-marrow function and incipient hematopoietic reconstitution after aplasia in patients with hematologic malignancies.
2017 Scientific Article in Magnetic Resonance Materials in Physics, Biology and Medicine Magn. Reson. Mater. Phys. Biol. Med. 30, 139-151 (2017)
Comparison of T1-weighted 2D TSE, 3D SPGR, and two-point 3D Dixon MRI for automated segmentation of visceral adipose tissue at 3 Tesla.
2017 Scientific Article in Nephrology Dialysis Transplantation Nephrol. Dial. Transplant. 32, 670-676 (2017)
Impact of end-stage renal disease on glucose metabolism-a matched cohort analysis.
2017 Scientific Article in Frontiers in Behavioral Neuroscience Front. Behav. Neurosci. 11:74 (2017)
Post-learning sleep transiently boosts context specific operant extinction memory.
2017 Scientific Article in Inorganic Chemistry Inorg. Chem. 56, 3123-3126 (2017)
Synthetic methods for the preparation of a functional analogue of Ru360, a potent inhibitor of mitochondrial calcium uptake.
2017 Scientific Article in Nutrients Nutrients 9:E48 (2017)
Diet quality during infancy and early childhood in children with and without risk of type 1 diabetes: A DEDIPAC Study.
2017 Scientific Article in Physiology & Behavior Physiol. Behav. 176, 134-138 (2017)
Hypothalamic insulin responsiveness is associated with pancreatic insulin secretion in humans.
2017 Scientific Article in Neonatology Neonatology 111, 189-194 (2017)
Reference ranges of reticulocyte haemoglobin content in preterm and term infants: A retrospective analysis.
2017 Scientific Article in Diabetes Diabetes 66, 886-896 (2017)
Regulation of glucose uptake and enteroendocrine function by the intestinal epithelial insulin receptor.
2017 Scientific Article in Neuroscience Neuroscience 357, 241-254 (2017)
Alterations in neuronal control of body weight and anxiety behavior by glutathione peroxidase 4 deficiency.
2017 Scientific Article in Archives of Toxicology Arch. Toxicol. 91, 3427–3438 (2017)
Time-matched analysis of DNA adduct formationand early gene expression as predictive tool for renal carcinogenesis in methylazoxymethanol acetate treated Eker rats.
2017 Meeting abstract in Molecular and Cellular Pediatrics Mol. Cell. Pediatr. 4, 1:5 (2017)
Abstracts of the 52nd Workshop for Pediatric Research : Frankfurt, Germany. 27-28 October 2016.
2017 Scientific Article in Scientific Reports Sci. Rep. 7:44661 (2017)
CD8+ T cells specific for the islet autoantigen IGRP are restricted in their T cell receptor chain usage.
2017 Scientific Article in Diabetes Diabetes 66, 1511-1520 (2017)
Endothelial HIF-1α enables hypothalamic glucose uptake to drive POMC neurons.
2017 Scientific Article in Cell Metabolism Cell Metab. 25, 1334-1347.e4 (2017)
N-acyl taurines and acylcarnitines cause an imbalance in insulin synthesis and secretion provoking β cell dysfunction in type 2 diabetes.
2017 Scientific Article in Journal of Diabetes and its Complications J. Diab. Complic. 31, 1058-1065 (2017)
ALCAM a novel biomarker in patients with type 2 diabetes mellitus complicated with diabetic nephropathy.
In: (Proteomic Forum 2017, 2-5 April 2017, Potsdam). 2017. 119-120
The proteomic landscape of patient-derived CD4+ T cells in recent-onset type 1 diabetes.
2017 Scientific Article in Biologie aujourd'hui Biol. Aujourdhui 210, 211-225 (2017)
[Hypothalamic inflammation and energy balance deregulations: Focus on chemokines.].
2017 Scientific Article in Critical Care Crit. Care 21:32 (2017)
Point-of-care testing for emergency assessment of coagulation in patients treated with direct oral anticoagulants.
2017 Scientific Article in Scientific Reports Sci. Rep. 7:2261 (2017)
The protective effect of human renal sinus fat on glomerular cells is reversed by the hepatokine fetuin-A.
2017 Scientific Article in Diabetologia Diabetologia 60, 1314-1324 (2017)
Lipoprotein lipase in hypothalamus is a key regulator of body weight gain and glucose homeostasis in mice.
2017 Scientific Article in Frontiers in Behavioral Neuroscience Front. Behav. Neurosci. 11:28 (2017)
Sleep enhances recognition memory for conspecifics as bound into spatial context.
2017 Scientific Article in Current Opinion in Clinical Nutrition & Metabolic Care Curr. Opin. Clin. Nutr. Metab. Care 20, 294-299 (2017)
Do diabetes and obesity affect the metabolic response to exercise?
2017 Scientific Article in Physiological Reviews Physiol. Rev. 97, 721-766 (2017)
The new biology and pharmacology of glucagon.
2017 Scientific Article in Cell Death and Differentiation Cell Death Differ. 24, 761-773 (2017)
SK2 channels regulate mitochondrial respiration and mitochondrial Ca2+ uptake.
2017 Scientific Article in Diabetes Diabetes 66, 2019-2032 (2017)
A low-frequency inactivating Akt2 variant enriched in the Finnish population is associated with fasting insulin levels and type 2 diabetes risk.
2017 Scientific Article in Acta Neuropathologica Acta Neuropathol. 134, 241–254 (2017)
Spinal poly-GA inclusions in a C9orf72 mouse model trigger motor deficits and inflammation without neuron loss.
2017 Scientific Article in Methods in Molecular Biology Methods Mol. Biol. 1567, 15-32 (2017)
Isolation of functional mitochondria from cultured cells and mouse tissues.
2017 Review in Journal of Neurogastroenterology and Motility J. Neurogastroenterol. Motil. 23, 197-207 (2017)
How to perform and interpret functional magnetic resonance imaging studies in functional gastrointestinal disorders.
2017 Scientific Article in PLoS ONE PLoS ONE 12:e0178563 (2017)
Improved efficacy of allergen-specific immunotherapy by JAK inhibition in a murine model of allergic asthma.
2017 Scientific Article in Diabetes Diabetes 66, 1247-1257 (2017)
Direct substrate delivery into mitochondrial-fission deficient pancreatic islets rescues insulin secretion.
2017 Scientific Article in Molecular Metabolism Mol. Metab. 6, 737-747 (2017)
Metformin causes a futile intestinal-hepatic cycle which increase energy expenditure and slows down development of a type 2 diabetes-like state.
2017 Scientific Article in Journal of Neuroscience Methods J. Neurosci. Methods, DOI: 10.1016/j.jneumeth.2017.05.005 (2017)
Analysis of locomotor behavior in the German Mouse Clinic.
2017 Scientific Article in Scientific Reports Sci. Rep. 7:2235 (2017)
Sex-specific metabolic profiles of androgens and its main binding protein SHBG in a middle aged population without diabetes.
2017 Scientific Article in Scientific Reports Sci. Rep. 7:2397 (2017)
Extensive phenotypic characterization of a new transgenic mouse reveals pleiotropic perturbations in physiology due to mesenchymal hGH minigene expression.
2017 Editorial in Science Science 355, 1124-1125 (2017)
METABOLISM. Fat controls U. Circulating uridine acts as a hunger signal.
2017 Review in Nature Reviews - Endocrinology Nat. Rev. Endocrinol. 13, 133-148 (2017)
Exercise-stimulated glucose uptake - regulation and implications for glycaemic control.
2017 Letter to the Editor in Diabetes Diabetes 66, e6-e6 (2017)
Response to comment on Ussar et al. Regulation of glucose uptake and enteroendocrine function by the intestinal epithelial insulin receptor. Diabetes 2017;66:886-896.
2017 Scientific Article in Nature Communications Nat. Commun. 8:15143 (2017)
TNFα drives mitochondrial stress in POMC neurons in obesity.
2017 Scientific Article in Molecular Psychiatry Mol. Psychiatry 23, 1345-1355 (2017)
A paternal methyl donor-rich diet altered cognitive and neural functions in offspring mice.
2017 Scientific Article in Diabetes Diabetes 66, 1373-1379 (2017)
Nonsuppressed glucagon after glucose challenge as a potential predictor for glucose tolerance.
2017 Scientific Article in Cardiovascular Research Cardiovasc. Res. 113, 711-724 (2017)
Sex in basic research - Concepts in the cardiovascular field.
2017 Scientific Article in Molecular Metabolism Mol. Metab. 6, 640-650 (2017)
A high-content small molecule screen identifies novel inducers of definitive endoderm.
2017 Scientific Article in Molecular and Cellular Endocrinology Mol. Cell. Endocrinol. 456, 87-94 (2017)
Small non coding RNAs in adipocyte biology and obesity.
2017 Scientific Article in British Journal of Nutrition Br. J. Nutr. 117, 466-472 (2017)
Maternal use of dietary supplements during pregnancy is not associated with coeliac disease in the offspring: The Environmental Determinants of Diabetes in the Young (TEDDY) study.
2017 Review in Cell Cell 168, 758-774 (2017)
Gut-brain cross-talk in metabolic control.
2017 Scientific Article in Molecular Metabolism Mol. Metab. 6, 440-446 (2017)
Monomeric GLP-1/GIP/glucagon triagonism corrects obesity, hepatosteatosis, and dyslipidemia in female mice.
2017 Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 102, 336-336 (2017)
Gestational diabetes impairs human fetal postprandial brain activity (vol 100, pg 4029, 2015).
2017 Molecular Psychiatry Mol. Psychiatry 22, 321-322 (2017)
Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index (vol 22, pg 192, 2017).
2017 Meeting abstract in Reproduction in domestic animals Reprod. Dom. Anim. 52, 24-24 (2017)
Impaired weight gain and disproportionate organ growth, but preserved fertility in growth hormone receptor deficient pigs (Laron syndrome).
2017 Scientific Article in Nature medicine Nat. Med. 23, 623-630 (2017)
Alternatively activated macrophages do not synthesize catecholamines or contribute to adipose tissue adaptive thermogenesis.
2017 Scientific Article in Physiology & Behavior Physiol. Behav. 176, 84-92 (2017)
Modulation of attentional networks by food-related disinhibition.
2017 Scientific Article in Frontiers in Neuroscience Front. Neurosci. 11:54 (2017)
Central nervous insulin administration before nocturnal sleep decreases breakfast intake in healthy young and elderly subjects.
2017 Scientific Article in Vaccine Vaccine 35, 1735-1741 (2017)
Vaccinations in early life are not associated with development of islet autoimmunity in type 1 diabetes high-risk children: Results from prospective cohort data.
2017 Scientific Article in Chemico-Biological Interactions Chem. Biol. Interact. 276, 182-193 (2017)
Characterization of AKR1B16, a novel mouse aldo-keto reductase.
2017 Scientific Article in Nature Communications Nat. Commun. 8:14428 (2017)
Foxa2 identifies a cardiac progenitor population with ventricular differentiation potential.
2017 Scientific Article in Metabolomics Metabolomics 13:48 (2017)
LysoPC-acyl C16:0 is associated with brown adipose tissue activity in men.
2017 Scientific Article in Appetite Appetite 112, 188-195 (2017)
Volitional regulation of brain responses to food stimuli in overweight and obese subjects: A real-time fMRI feedback study.
2017 Scientific Article in Physiology & Behavior Physiol. Behav. 176, 31-39 (2017)
Current findings on the role of oxytocin in the regulation of food intake.
2017 Scientific Article in Scientific Reports Sci. Rep. 7, 42056 (2017)
The Rb1 tumour suppressor gene modifies telomeric chromatin architecture by regulating TERRA expression.
2017 Scientific Article in Scientific Reports Sci. Rep. 7:44041 (2017)
The redox environment triggers conformational changes and aggregation of hIAPP in Type II Diabetes.
2017 Scientific Article in Journal of Thermal Biology J. Therm. Biol. 68, 83-88 (2017)
Phylogenetic analysis of the allometry of metabolic rate and mitochondrial basal proton leak.
2017 Scientific Article in Molecular and Cellular Endocrinology Mol. Cell. Endocrinol. 443, 106-113 (2017)
Teneurin-2 (TENM2) deficiency induces UCP1 expression in differentiating human fat cells.
2017 Review in Trends in Neurosciences Trends Neurosci. 40, 167-180 (2017)
Current understanding of the hypothalamic ghrelin pathways inducing appetite and adiposity.
2017 Scientific Article in EBioMedicine EBioMedicine 16, 204-211 (2017)
Human neutrophil peptide 1 Limits hypercholesterolemia-induced atherosclerosis by increasing hepatic LDL clearance.
2017 Scientific Article in Science Translational Medicine Sci. Transl. Med. 9:eaaf8848 (2017)
A divergent population of autoantigen-responsive CD4+ T cells in infants prior to β cell autoimmunity.
2017 Editorial in Diabetes Diabetes 66, 256-257 (2017)
Bonding with beta-cells-a role for oxytocin in glucose handling.
2017 Scientific Article in Journal of Clinical Investigation J. Clin. Invest. 127, 695-708 (2017)
Acute dietary fat intake initiates alterations in energy metabolism and insulin resistance.
2017 Scientific Article in Particle and Fibre Toxicology Part. Fibre Toxicol. 14:2 (2017)
Nanoparticle exposure reactivates latent herpesvirus and restores a signature of acute infection.
2017 Scientific Article in PLoS ONE PLoS ONE 12:e0169223 (2017)
Maternal pre-pregnancy obesity is associated with altered placental transcriptome.
2017 Scientific Article in Metabolomics Metabolomics 13:28 (2017)
Cinnamon: Does it hold its promises in cows? Using non-targeted blood serum metabolomics profiling to test the effects of feeding cinnamon to dairy cows undergoing lactation-induced insulin resistance.
2017 Scientific Article in Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet. 26, 90-94 (2017)
Diabetes mellitus and bone metabolism.
2017 Scientific Article in JAMA Pediatrics JAMA Pediatr. 171, 16-22 (2017)
Effect of increased enteral protein intake on growth in human milk-fed preterm infants a randomized clinical trial.
2017 Scientific Article in Biochimica et Biophysica Acta - Molecular Basis of Disease Biochim. Biophys. Acta-Mol. Basis Dis. 1863, 1605-1614 (2017)
Modification of the fatty acid composition of an obesogenic diet improves the maternal and placental metabolic environment in obese pregnant mice.
2017 Scientific Article in Biochimica et Biophysica Acta Biochim. Biophys. Acta 1863, 654-662 (2017)
A scavenger peptide prevents methylglyoxal induced pain in mice.
2017 Scientific Article in Stem Cell Reports Stem Cell Rep. 8, 21-29 (2017)
SNEVhPrp19/hPso4 regulates adipogenesis of human adipose stromal cells.
2017 Scientific Article in Journal of Biological Chemistry, The J. Biol. Chem. 292, 685-690 (2017)
Evidence against a role for the parkinsonism-associated protein DJ-1 in methylglyoxal detoxification.
2017 Review in Trends in Endocrinology and Metabolism Trends Endocrinol. Metab. 28, 104-120 (2017)
Genome-wide insights into the development and function of thermogenic adipocytes.
2017 Scientific Article in Diabetologia Diabetologia 60, 35-38 (2017)
Rebranding asymptomatic type 1 diabetes: The case for autoimmune beta cell disorder as a pathological and diagnostic entity.
2017 Other: Opinion in JAMA Pediatrics JAMA Pediatr. 171, 93 (2017)
Miscalculation and errors in numbers reported in table.
2017 Scientific Article in Diabetes Care Diabetes Care 40, 398-404 (2017)
First infant formula type and risk of islet autoimmunity in the environmental determinants of diabetes in the young (TEDDY) study.
2017 Scientific Article in Molecular Metabolism Mol. Metab. 6, 256-266 (2017)
Bezafibrate ameliorates diabetes via reduced steatosis and improved hepatic insulin sensitivity in diabetic TallyHo mice.
2017 Scientific Article in Diabetes, Obesity and Metabolism Diabetes Obes. Metab. 19, 599-603 (2017)
Robust GLP-1 secretion by basic L-amino acids does not require the GPRC6A receptor.
2017 Review in Biochimie Biochimie 134, 77-85 (2017)
Targeted mitochondrial uncoupling beyond UCP1 - The fine line between death and metabolic health.
2017 Scientific Article in Disease Models and Mechanisms Dis. Model. Mech. 10, 163-171 (2017)
Broad AOX expression in a genetically tractable mouse model does not disturb normal physiology.
2017 Scientific Article in Journal of Molecular Endocrinology J. Mol. Endocrinol. 58, 67-68 (2017)
Genetic characterization of a mouse line with primary aldosteronism.
2017 Scientific Article in Metabolomics Metabolomics 13:4 (2017)
Stability of targeted metabolite profiles of urine samples under different storage conditions.
2017 Scientific Article in Nucleic Acids Research Nucleic Acids Res. 45, 3031-3045 (2017)
Interplay between H1 and HMGN epigenetically regulates OLIG1&2 expression and oligodendrocyte differentiation.
2017 Scientific Article in Experimental Cell Research Exp. Cell Res. 350, 242-252 (2017)
Functional properties of hepatocytes in vitro are correlated with cell polarity maintenance.
2017 Scientific Article in Endocrine-Related Cancer Endocr. Relat. Cancer 24, 1-15 (2017)
Targeting PI3K/mTOR signaling exerts potent antitumor activity in pheochromocytoma in vivo.
2017 Scientific Article in Nature Chemical Biology Nat. Chem. Biol. 13, 91-98 (2017)
ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition.
2017 Scientific Article in Diabetologia Diabetologia 60, 287-295 (2017)
Peptide serum markers in islet autoantibody-positive children.
2017 Scientific Article in Journal of Diabetes and its Complications J. Diab. Complic. 31, 304-310 (2017)
Reduction in ins-7 gene expression in non-neuronal cells of high glucose exposed Caenorhabditis elegans protects from reactive metabolites, preserves neuronal structure and head motility, and prolongs lifespan.
2017 Scientific Article in Gastroenterology Gastroenterology 152, 571-585.e8 (2017)
Isocaloric diets high in animal or plant protein reduce liver fat and inflammation in individuals with Type 2 Diabetes.
2017 Scientific Article in Annals of the New York Academy of Sciences Ann. NY Acad. Sci. 1391, 71-84 (2017)
The role of primary cilia in obesity and diabetes.
2017 Scientific Article in Diabetes Diabetes 66, 264-271 (2017)
Oxytocin improves beta-cell responsivity and glucose tolerance in healthy men.
2017 Scientific Article in Journal of Magnetic Resonance Imaging J. Magn. Reson. Imaging 45, 369-380 (2017)
In vivo assessment of cold stimulation effects on the fat fraction of brown adipose tissue using DIXON MRI.
2017 Scientific Article in Journal of Psychopharmacology J. Psychopharmacol. 31, 204-210 (2017)
Signs of enhanced sleep and sleep-associated memory processing following the anti-inflammatory antibiotic minocycline in men.
2017 Scientific Article in Molecular Psychiatry Mol. Psychiatry 22, 192-201 (2017)
Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index.
2017 Scientific Article in Diabetes/Metabolism Research and Reviews Diabetes Metab. Res. Rev. 33:e2811 (2017)
Association of transketolase polymorphisms with measures of polyneuropathy in patients with recently diagnosed diabetes.
2017 Scientific Article in Endocrine Endocrine 55, 386-397 (2017)
Loss of p27 expression is associated with MEN1 gene mutations in sporadic parathyroid adenomas.
2017 Review in Pediatric Diabetes Pediatr. Diabetes 18, 103-110 (2017)
Associations of growth patterns and islet autoimmunity in children with increased risk for type 1 diabetes: A functional analysis approach.
2016 Scientific Article in Journal of applied laboratory medicine J. Appl. Lab. Med. 1, 129-142 (2016)
Inter-Laboratory Robustness of Next-Generation Bile Acid Study in Mice and Humans: International Ring Trial Involving 12 Laboratories.
2016 Scientific Article in Annals of transplantation Ann. Transplant. 21, 39-45 (2016)
The medically complex living kidney donor: Glucose metabolism as principal cause of donor declination.
2016 Review in Reviews in Endocrine & Metabolic Disorders Rev. Endocr. Metab. Disord. 17, 51-60 (2016)
Perivascular adipose tissue: An unique fat compartment relevant for the cardiometabolic syndrome.
2016 Scientific Article in Wiener klinische Wochenschrift Wien. Klin. Wochenschr. 128 Suppl 2, S216-S228 (2016)
Austrian Lipid Consensus on the management of metabolic lipid disorders to prevent vascular complications: A joint position statement issued by eight medical societies. 2016 update.
2016 Meeting abstract in Diabetologia Diabetologia 59, S521-S521 (2016)
Impaired lung function as a diabetes related complication.
2016 Meeting abstract in Diabetologia Diabetologia 59, S234-S234 (2016)
Transforming growth factor beta-like stimulated clone 22 D4 promotes diabetic hyperglycaemia and insulin resistance.
2016 Meeting abstract in Diabetologia Diabetologia 59, S550-S550 (2016)
Are recommended goals for secondary prevention of myocardial infarction or stroke achieved in real life? A German/Austrian DPV analysis of 29,325 patients with type 2 diabetes.
2016 Meeting abstract in Diabetologia Diabetologia 59, S187-S187 (2016)
Lactation is associated with altered metabolomic signatures in women with gestational diabetes.
2016 Meeting abstract in Diabetologia Diabetologia 59, S142-S143 (2016)
A metabolite ratio associates with measures of insulin secretion and altered risk of type 2 diabetes; a DIRECT study.
2016 Meeting abstract in Diabetologia Diabetologia 59, S274-S274 (2016)
Mitogenic activity of the metabolically relevant hepatokine FGF21 in human carcinoma cells.
2016 Meeting abstract in Diabetologia Diabetologia 59, S171-S171 (2016)
Liver fat content and insulin secretion failure are associated with the long-term success of a lifestyle intervention to prevent type 2 diabetes: Results of the TULIP study.
2016 Meeting abstract in Diabetologia Diabetologia 59, S217-S217 (2016)
Crosstalk of fatty liver with fatty pancreas impairs islet function in humans.
2016 Meeting abstract in Diabetologia Diabetologia 59, S168-S168 (2016)
Identification and functional characterisation of diabetes genes in mice.
2016 Meeting abstract in Diabetologia Diabetologia 59, S79-S79 (2016)
The interplay of fatty liver with fatty pancreas accenuates local islet inflammation in humans.
2016 Meeting abstract in Diabetologia Diabetologia 59, S67-S67 (2016)
Specific phospholipids are differently associated to human visceral and non-visceral adipose tissue depending on the inflammatory state in the NUGAT Twin study.
2016 Meeting abstract in Diabetologia Diabetologia 59, S47-S47 (2016)
miRNA signatures in maternal whole blood cells of women with gestational diabetes.
2016 Meeting abstract in Diabetologia Diabetologia 59, S307-S307 (2016)
Polycomb controls metabolic homeostasis through a novel liver-to-adipose axis.
2016 Meeting abstract in Diabetologia Diabetologia 59, S259-S259 (2016)
Systemic metabolic effects exerted by a point mutation in the RED subdomain of PAX6.
2016 Meeting abstract in Diabetologia Diabetologia 59, S188-S188 (2016)
Dll1-and Dll4-mediated Notch signalling in adult pancreatic beta cells is essential for the structural integrity of islets and maintenance of glucose homeostasis.
2016 Meeting abstract in Diabetologia Diabetologia 59, S127-S127 (2016)
Targeted metabolomics to predict the primary success of metformin monotherapy in type 2 diabetes.
2016 Meeting abstract in Atherosclerosis Atherosclerosis 252, E131-E131 (2016)
Liposomes for microRNA delivery to human adipocytes.
2016 Scientific Article in Journal of Biological Chemistry, The J. Biol. Chem. 292, 3224-3238 (2016)
Loss of glyoxalase 1 induces compensatory mechanism to achieve dicarbonyl detoxification in mammalian Schwann cells.
2016 Scientific Article in Journal of empirical research on human research ethics J. Empir. Res. Hum. Res. Ethics 11, 106-114 (2016)
Parental estimation of their child's increased type 1 diabetes risk during the first 2 years of participation in an international observational study: Results from the TEDDY study.
2016 Scientific Article in BMJ Open BMJ Open 6:e013835 (2016)
Time-saving screening for diabetes in patients with coronary artery disease: A report from EUROASPIRE IV.
2016 Scientific Article in Nutrients Nutrients 8:802 (2016)
Effects of low versus high glycemic index sugar-sweetened beverages on postprandial vasodilatation and inactivity-induced impairment of glucose metabolism in healthy men.
2016 Scientific Article in American Journal of Physiology - Regulatory, Integrative and Comparative Physiology Am. J. Physiol.-Regul. Integr. Comp. Physiol. 311, R637-R642 (2016)
Nocturnal sleep uniformly reduces numbers of different T-cell subsets in the blood of healthy men.
2016 Scientific Article in The proceedings of the Nutrition Society Proc. Nutr. Soc. 76, 316-327 (2016)
The determinants of food choice.
2016 Scientific Article in Stem Cell Research Stem Cell Res. 17, 292-295 (2016)
Generation of a human induced pluripotent stem cell (iPSC) line from a patient with family history of diabetes carrying a C18R mutation in the PDX1 gene.
2016 Scientific Article in Stem Cell Research Stem Cell Res. 17, 273-276 (2016)
Generation of a human induced pluripotent stem cell (iPSC) line from a patient carrying a P33T mutation in the PDX1 gene.
2016 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 101, 5044-5052 (2016)
Liver and muscle contribute differently to the plasma acylcarnitine pool during fasting and exercise in humans.
2016 Scientific Article in Biochimica et Biophysica Acta Biochim. Biophys. Acta 1863, 1054-1065 (2016)
Positive feedback amplifies the response of mitochondrial membrane potential to glucose concentration in clonal pancreatic beta cells.
2016 Letter to the Editor in Obstetrical & gynecological survey Obstet. Gynecol. Surv. 71, 719-720 (2016)
Epigenetic germline inheritance of diet-induced obesity and insulin resistance.
2016 Scientific Article in PLoS Pathogens PLoS Pathog. 12:e1005405 (2016)
A viral microRNA cluster regulates the expression of PTEN, p27 and of a bcl-2 homolog.
2016 Meeting abstract in Allergy Allergy 71, 507-507 (2016)
Experimental allergen-specific immunotherapy under the umbrella of JAK1/3 pathway inhibition substantial improved local parameters of allergic airway inflammation.
2016 Meeting abstract in Allergy Allergy 71, 47-47 (2016)
Alum-free thermosensitive hydrogel as matrix for immunomodulatory substances and allergens during allergen-specific immunotherapy.
2016 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 193 (2016)
Mouse lung developmental gene expression profiling study identifies novel candidate genes for pulmonary function.
2016 Meeting abstract in American Journal of Respiratory and Critical Care Medicine Am. J. Respir. Crit. Care Med. 193 (2016)
Reduced expression of the epigenetic regulator Hmgn5 enhances susceptibility to emphysema.
2016 Scientific Article in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 11, 357-360 (2016)
Silvia-King Award 2016: Central nervous insulin signaling in sleep-dependent memory formation and neuroendocrine regulation.
2016 Scientific Article in Molecular Neurobiology Mol. Neurobiol. 54, 8242–8262 (2016)
Serum response factor (SRF) ablation interferes with acute stress-associated immediate and long-term coping mechanisms.
2016 Scientific Article in International Journal of Molecular Sciences Int. J. Mol. Sci. 17:2011 (2016)
Comprehensive analysis of miRNome alterations in response to sorafenib treatment in colorectal cancer cells.
2016 Scientific Article in Recent Results in Cancer Research Recent Results Cancer Res. 208, 219-242 (2016)
Biological mechanisms for the effect of obesity on cancer risk: Experimental evidence.
2016 Scientific Article in Best Practice and Research Clinical Endocrinology and Metabolism Best Pract. Res. Clin. Endocrinol. Metab. 30, 653-664 (2016)
MicroRNAs in adipocyte formation and obesity.
2016 Review in Nature Reviews - Nephrology Nat. Rev. Nephrol. 12, 721-737 (2016)
The impact of insulin resistance on the kidney and vasculature.
2016 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 101, 4743-4751 (2016)
Genetic variation in the 11β-hydroxysteroid-dehydrogenase 1 gene determines NAFLD and visceral obesity.
2016 Scientific Article in Journal of Clinical Investigation J. Clin. Invest. 126, 4430-4443 (2016)
Antibiotic effects on gut microbiota and metabolism are host dependent.
2016 Scientific Article in Deutsches Ärzteblatt Dtsch. Ärztebl. 113, 27-29 (2016)
Das Mikrobiom: Einfluss auf Adipositas und Diabetes.
2016 Scientific Article in Nature Communications Nat. Commun. 7:13267 (2016)
Control of diabetic hyperglycaemia and insulin resistance through TSC22D4.
2016 Scientific Article in South African Journal of Botany S. Afr. J. Bot., DOI: 10.1016/j.sajb.2016.08.007 (2016)
A polyphenol-enriched fraction of Cyclopia intermedia decreases lipid content in 3T3-L1 adipocytes and reduces body weight gain of obese db/db mice.
2016 Meeting abstract in Neuroendocrinology Neuroendocrinology 103, 8-8 (2016)
The Role of p27 in Pheochromocytoma Development.
2016 Scientific Article in Molecular Metabolism Mol. Metab. 5, 1015-24 (2016)
Fibroblast activation protein (FAP) as a novel metabolic target.
2016 Scientific Article in Diabetes Diabetes 65, 3233-3239 (2016)
Type 1 diabetes prevention: A goal dependent on accepting a diagnosis of an asymptomatic disease.
2016 Scientific Article in Lecture Notes in Computer Science Lect. Notes Comput. Sc. 10019, 287-295 (2016)
Mitosis detection in intestinal crypt images with hough forest and conditional random fields.
2016 Scientific Article in Scientific Reports Sci. Rep. 6:37005 (2016)
12-months metabolic changes among gender dysphoric individuals under cross-sex hormone treatment: A targeted metabolomics study.
2016 Scientific Article in Nature medicine Nat. Med. 22, 1428-1438 (2016)
Cardioprotection and lifespan extension by the natural polyamine spermidine.
2016 Scientific Article in BMC Endocrine Disorders BMC Endocr. Disord. 16:56 (2016)
The effect of lifestyle intervention in obesity on the soluble form of activated leukocyte cell adhesion molecule.
2016 Scientific Article in Genes Genomes Genetics G3 Genes Genomes Genetics G3 6, 4035-4046 (2016)
The first Scube3 mutant mouse line with pleiotropic phenotypic alterations.
2016 Scientific Article in Drug research Drug Res. (Stuttg) 66, S.10 (2016)
Diabetes Type 2 Treatments.
2016 Scientific Article in PLoS ONE PLoS ONE 11:e0159199 (2016)
Measurement of the absolute magnitude and time courses of mitochondrial membrane potential in primary and clonal pancreatic beta-cells.
2016 Scientific Article in Acta Diabetologica Acta Diabetol. 53, 1037-1044 (2016)
A novel insulin sensitivity index particularly suitable to measure insulin sensitivity during gestation.
2016 Scientific Article in Journal of Psychosomatic Research J. Psychosomat. Res. 91, 9-11 (2016)
Effectiveness of a placebo intervention on visually induced nausea in women – A randomized controlled pilot study.
2016 Scientific Article in Proceedings of the National Academy of Sciences of the United States of America Proc. Natl. Acad. Sci. U.S.A. 113, E6659-E6668 (2016)
miRNA92a targets KLF2 and the phosphatase PTEN signaling to promote human T follicular helper precursors in T1D islet autoimmunity.
2016 Scientific Article in Molecular Neurodegeneration Mol. Neurodegener. 11:67 (2016)
Seizure protein 6 and its homolog seizure 6-like protein are physiological substrates of BACE1 in neurons.
2016 Scientific Article in Circulation: Cardiovascular Genetics Circ. Cardiovasc. Genet. 9, 487-494 (2016)
Cardiovascular risk factors associated with blood metabolite concentrations and their alterations over a 4-year period in a population-based cohort.
2016 Scientific Article in PLoS ONE PLoS ONE 11:e0164298 (2016)
Sphingomyelin synthase 1 is essential for male fertility in mice.
2016 Review in Skeletal muscle Skelet. Muscle 6:33 (2016)
The functional significance of the skeletal muscle clock: Lessons from Bmal1 knockout models.
2016 Editorial in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 11, 266-267 (2016)
The German center for diabetes research Tailor-made prevention of type-2-diabetes.
2016 Scientific Article in Journal of Neuroendocrinology J. Neuroendocrinol. 28 (2016)
Seasonal control of mammalian energy balance: Recent advances in the understanding of daily torpor and hibernation.
2016 Meeting abstract in European Journal of Immunology Eur. J. Immunol. 46, 189-189 (2016)
System-level effects of ectopic galectin-7 reconstitution in cervical cancer and their microenvironment.
2016 Scientific Article in Nature Reviews - Endocrinology Nat. Rev. Endocrinol. 12, 695-709 (2016)
Impact of islet architecture on β-cell heterogeneity, plasticity and function.
2016 Scientific Article in PLoS ONE PLoS ONE 11:e0162124 (2016)
Sustained treatment with insulin detemir in mice alters brain activity and locomotion.
2016 Scientific Article in International Journal of Obesity Int. J. Obes. 40, 1707-1714 (2016)
Oxytocin's inhibitory effect on food intake is stronger in obese than normal-weight men.
2016 Scientific Article in Immunity Immunity 45, 761-773 (2016)
K+ efflux-independent NLRP3 inflammasome activation by small molecules targeting mitochondria.
2016 Scientific Article in Monoclonal Antibodies in Immunodiagnosis and Immunotherapy Monoclon. Antib. Immunodiagn. Immunother. 35, 259-262 (2016)
Generation of Pax1/PAX1-specific monoclonal antibodies.
2016 Scientific Article in Proceedings of the National Academy of Sciences of the United States of America Proc. Natl. Acad. Sci. U.S.A. 113, E6467-E6475 (2016)
Epstein-Barr virus microRNAs reduce immune surveillance by virus-specific CD8+ T cells.
2016 Review in Neurogastroenterology and motility Neurogastroenterol. Mot. 28, 793-805 (2016)
Functional neuroimaging studies in functional dyspepsia patients: A systematic review.
2016 Scientific Article in Biochimica et Biophysica Acta Biochim. Biophys. Acta 1861, 1980-1992 (2016)
Lysophosphatidylcholines activate PPARδ and protect human skeletal muscle cells from lipotoxicity.
2016 Scientific Article in Molecular Metabolism Mol. Metab. 5, 807-822 (2016)
α-Melanocyte stimulating hormone promotes muscle glucose uptake via melanocortin 5 receptors.
2016 Scientific Article in Journal of natural medicines J. Nat. Med. 22, 970-971 (2016)
Obesity: Will withaferin win the war?
2016 Meeting abstract in Journal of Neurochemistry J. Neurochem. 138, 1, 422-422 (2016)
TREM2-deficiency reduces the efficacy of immunotherapeutic amyloid clearance.
2016 Scientific Article in Cell Cell 167, 843-857.e14 (2016)
Chemical hybridization of glucagon and thyroid hormone optimizes therapeutic Impact for metabolic disease.
2016 Meeting abstract in Journal of Investigative Dermatology, The J. Invest. Dermatol. 136, 2, S231-S231 (2016)
Alum-free thermosensitive hydrogel as subcutaneous matrix for immunomodulators and allergens during specific immunotherapy.
2016 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 101, 4730-4742:jc20162588 (2016)
Metabolic fingerprints of circulating IGF-I and the IGF-I/IGFBP-3 ration: A multi-fluid metabolomics study.
2016 Review in Diabetologia Diabetologia 59, 2497-2502 (2016)
Key elements of metabolomics in the study of biomarkers of diabetes.
2016 Scientific Article in Molecular Metabolism Mol. Metab. 5, 615-25 (2016)
miR-125b affects mitochondrial biogenesis and impairs brite adipocyte formation and function.
2016 Scientific Article in Diabetes Diabetes 66, 272-286:db160381 (2016)
Adipocyte glucocorticoid receptor deficiency attenuates aging and HFDinduced obesity, and impairs the feedingfasting transition.
2016 Scientific Article in Journal of Chromatography J. Chromatogr. B 1033-1034, 413-420 (2016)
Determination of thyroid hormones in mouse tissues by isotope-dilution microflow liquid chromatography-mass spectrometry method.
Frankfurt am Main: Lang, Peter, 2016. 388 S.
Zivilisationskrankheiten – Für eine gesamtwissenschaftliche Prädiktion und Prävention. Molekulare, phänomenologische, systemische und gestalttheoretische Analyse von Altersdiabetes.
München, Technische Universität, Fakultät für Medizin, Diss., 2016, 171 S.
The role of Oct4 in murine endoderm development.
2016 Scientific Article in MMW - Fortschritte der Medizin MMW-Fortschr. Med. 158, 65-67 (2016)
[Early diagnosis, early care - "Fr1da" screening of children for type 1 diabetes].
München, Technische Universität, Fakultät für Medizin, Diss., 2016, 123 S.
Integrative analysis of microRNA and mRNA expression profiles in osteosarcoma cell lines.
2016 Scientific Article in Mammalian Genome Mamm. Genome 27, 587-598 (2016)
Viable EdnraY129F mice feature human mandibulofacial dysostosis with alopecia (MFDA) syndrome due to the homologue mutation.
2016 Scientific Article in Nature Nature 537, 508-514 (2016)
High-throughput discovery of novel developmental phenotypes.
2016 Scientific Article in Journal of Experimental Medicine J. Exp. Med. 213, 2065-2080 (2016)
Epstein-Barr viral miRNAs inhibit antiviral CD4+ T cell responses targeting IL-12 and peptide processing.
2016 Scientific Article in Diabetes Diabetes 65, 3776-3785 (2016)
Metformin effect on non-targeted metabolite profiles in patients with type 2 diabetes and multiple murine tissues.
2016 Scientific Article in Gut (eGut) Gut 67, 146-156 (2016)
Dynamic landscape of pancreatic carcinogenesis reveals early molecular networks of malignancy.
2016 Scientific Article in BioTechniques / Protocol Guide BioTechniques 61, 137-148 (2016)
Characterization of aggregate load and pattern in living yeast cells by flow cytometry.
2016 Scientific Article in Diabetologia Diabetologia 59, 1-10 (2016)
Interaction between the obesity-risk gene FTO and the dopamine D2 receptor gene ANKK1/TaqIA on insulin sensitivity.
2016 Review in Molecular Metabolism Mol. Metab. 5, 795-803 (2016)
Interactions between host genetics and gut microbiome in diabetes and metabolic syndrome.
2016 Editorial in Monatsschrift Kinderheilkunde Mon.schr. Kinderheilkd. 164, 639-641 (2016)
Fr1da-insulin-intervention study.Treatment of beta cell-autoimmunity by antigen-desensitization.
2016 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 101, 2816-2825 (2016)
Exercise-induced secretion of FGF21 and follistatin are blocked by pancreatic clamp and impaired in type 2 diabetes.
2016 Meeting abstract in Journal of Immunology J. Immunol. 196, 1 (2016)
The transcriptional regulator Bcl-3 impaires the function of regulatory T cells leading to the development of intestinal inflammation.
2016 Scientific Article in BMC Pregnancy and Childbirth BMC Pregnancy Childbirth 16:266 (2016)
Does charge-free screening improve detection of gestational diabetes in women from deprived areas: A cross-sectional study.
2016 Scientific Article in Scientific Reports Sci. Rep. 6:32899 (2016)
Incomplete immune response to coxsackie B viruses associates with early autoimmunity against insulin.
2016 Scientific Article in Journal of the American Society of Nephrology J. Am. Soc. Nephrol. 28, 761-768 (2016)
Hyperoxaluria requires TNF receptors to initiate crystal adhesion and kidney stone disease.
2016 Scientific Article in BMC Cancer BMC Cancer 16:680 (2016)
Systems-level effects of ectopic galectin-7 reconstitution in cervical cancer and its microenvironment.
2016 Scientific Article in Glycoconjugate Journal Glycoconj. J. 34, 393–404 (2016)
A novel biological function of soluble biglycan: Induction of erythropoietin production and polycythemia.
2016 Scientific Article in Data in Brief Data Brief 8, 1395-1399 (2016)
Dataset of the associations of aldosterone to renin ratio with MR-proANP and MR-proADM.
2016 Scientific Article in Journal of Clinical Investigation J. Clin. Invest. 126, 3263-3278 (2016)
A liver stress-endocrine nexus promotes metabolic integrity during dietary protein dilution.
2016 Scientific Article in Glia Glia 64, 1962-1971 (2016)
The insulin-like growth factor I receptor regulates glucose transport by astrocytes.
2016 Scientific Article in Atherosclerosis Atherosclerosis 252, 88-96 (2016)
Altered relation of the renin-aldosterone system and vasoactive peptides in type 2 diabetes: The KORA F4 study.
2016 Scientific Article in Journal of natural medicines J. Nat. Med. 22, 1120-1130 (2016)
An AMP-activated protein kinase-stabilizing peptide ameliorates adipose tissue wasting in cancer cachexia in mice.
2016 Scientific Article in Cell Cell 166, 867-880 (2016)
Astrocytic insulin signaling couples brain glucose uptake with nutrient availability.
2016 Scientific Article in Journal of Bioenergetics and Biomembranes J. Bioenerg. Biomembr. 48, 413-423 (2016)
Role of mitochondrial complex I and protective effect of CoQ10 supplementation in propofol induced cytotoxicity.
2016 Scientific Article in Clinica Chimica Acta Clin. Chim. Acta 462, 60-64 (2016)
3 screen islet cell autoantibody ELISA: A sensitive and specific ELISA for the combined measurement of autoantibodies to GAD65, TO IA-2 and TO ZnT8.
2016 Scientific Article in Investigative Ophthalmology & Visual Science, IOVS Invest. Ophthalmol. Vis. Sci. 57, 4504-4511 (2016)
Immunological characterization of intraocular lymphoid follicles in a spontaneous recurrent uveitis model.
2016 Letter to the Editor in JAMA: Journal of the American Medical Association JAMA 316, 883-883:883 (2016)
Association of infection in early life and risk of developing type 1 diabetes - reply.
2016 Scientific Article in American Journal of Human Genetics, The Am. J. Hum. Genet. 99, 735-743 (2016)
Absence of the autophagy adaptor SQSTM1/p62 causes childhood-onset neurodegeneration with ataxia, dystonia, and gaze palsy.
2016 Scientific Article in Diabetes Technology & Therapeutics Diabetes Technol. Ther. 18, 687-693 (2016)
3 screen ELISA for high-throughput detection of beta cell autoantibodies in capillary blood.
2016 Scientific Article in Frontiers in Endocrinology Front. Endocrin. 7:109 (2016)
Ring finger protein 11 inhibits melanocortin 3 and 4 receptor signaling.
2016 Scientific Article in Archives of Physiology and Biochemistry Arch. Physiol. Biochem. 122, 281-288 (2016)
Impact of fibroblast growth factor 21 on the secretome of human perivascular preadipocytes and adipocytes: A targeted proteomics approach.
2016 Scientific Article in Neuropharmacology Neuropharmacol. 110, 396-406 (2016)
GLP-1 and estrogen conjugate acts in the supramammillary nucleus to reduce food-reward and body weight.
2016 Scientific Article in Nature Communications Nat. Commun. 7:12397 (2016)
MRF4 negatively regulates adult skeletal muscle growth by repressing MEF2 activity.
2016 Scientific Article in Journal of vascular surgery J. Vasc. Surg. 64, 990-994 (2016)
Reduced glyoxalase 1 activity in carotid artery plaques of nondiabetic patients with increased hemoglobin A1c level.
2016 Scientific Article in Physiological Reviews Physiol. Rev. 96, 1169-1209 (2016)
Brain insulin resistance at the crossroads of metabolic and cognitive disorders in humans.
2016 Scientific Article in Molecular Metabolism Mol. Metab. 5, 646-655 (2016)
MTORC2 and AMPK differentially regulate muscle triglyceride content via perilipin 3.
2016 Editorial in Cell Metabolism Cell Metab. 24, 194-195 (2016)
Metabolic precision medicines: Curing POMC deficiency.
2016 Scientific Article in PLoS ONE PLoS ONE 11:e0159199 (2016)
Measurement of the absolute magnitude and time courses of mitochondrial membrane potential in primary and clonal pancreatic beta-cells.
2016 Letter to the Editor in Journal of Physiology - Paris J. Physiol. 594, 3161-3162 (2016)
Inactivation of the intrinsic muscle clock does not cause sarcopenia.
2016 Scientific Article in Diabetes Diabetes 65, 3200-3211 (2016)
Genome-wide association study of the modified Stumvoll Insulin Sensitivity Index identifies BCL2 and FAM19A2 as novel insulin sensitivity loci.
2016 Scientific Article in Early Human Development Early Hum. Dev. 100, 61-66 (2016)
Neuromagnetic signatures of syllable processing in fetuses and infants provide no evidence for habituation.
2016 Review in Diabetologia Diabetologia 59, 1838-1842 (2016)
Targeting insulin-producing beta cells for regenerative therapy.
2016 Scientific Article in Scientific Reports Sci. Rep. 6:23673 (2016)
Ghrelin regulates glucose and glutamate transporters in hypothalamic astrocytes.
2016 Scientific Article in Cell Cell 164, 353-364 (2016)
Trim28 haploinsufficiency triggers bi-stable epigenetic obesity.
2016 Scientific Article in Diabetologia Diabetologia 59, 2172-2180 (2016)
A novel approach for the analysis of longitudinal profiles reveals delayed progression to type 1 diabetes in a subgroup of multiple-islet-autoantibody-positive children.
2016 Scientific Article in Diabetologia Diabetologia 59, 2193-2202 (2016)
Lactation is associated with altered metabolomic signatures in women with gestational diabetes.
2016 Scientific Article in Nature Nature 535, 430-434 (2016)
Identification of proliferative and mature β-cells in the islets of Langerhans.
2016 Scientific Article in PLoS ONE PLoS ONE 11:e0157885 (2016)
Association between thigh muscle volume and leg muscle power in older women.
2016 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 101, 550-560 (2016)
Circulating follistatin is liver-derived and regulated by the glucagon-to-insulin ratio.
2016 Scientific Article in NeuroImage - a Journal of Brain Function Neuroimage 142, 465-473 (2016)
Ghrelin modulates encoding-related brain function without enhancing memory formation in humans.
2016 Scientific Article in EMBO Molecular Medicine EMBO Mol. Med. 8, 992-1004 (2016)
TREM2 deficiency reduces the efficacy of immunotherapeutic amyloid clearance.
2016 Review in Cell Metabolism Cell Metab. 24, 51-62 (2016)
Unimolecular polypharmacy for treatment of diabetes and obesity.
2016 Scientific Article in Nature Nature 536, 41-47 (2016)
The genetic architecture of type 2 diabetes.
2016 Scientific Article in Nature Nature 535, 299-302 (2016)
Early myeloid lineage choice is not initiated by random PU.1 to GATA1 protein ratios.
2016 Scientific Article in Scientific Reports Sci. Rep. 6:28613 (2016)
Let-7i-5p represses brite adipocyte function in mice and humans.
2016 Scientific Article in Diabetes Aktuell Diabetes akt. 14, 186-191 (2016)
Gestationsdiabetes postpartal – Typ-2-Diabetes-Risikoabschätzung und präventive Therapie.
2016 Scientific Article in Diabetologia Diabetologia 59, 1806-1818 (2016)
Novel phenotypes of prediabetes?
2016 Review in Journal of Biotechnology J. Biotechnol. 235, 150-161 (2016)
A signature of 12 microRNAs is robustly associated with growth rate in a variety of CHO cell lines.
2016 Scientific Article in Appetite Appetite 105, 562-566 (2016)
Glycemic increase induced by intravenous glucose infusion fails to affect hunger, appetite, or satiety following breakfast in healthy men.
2016 Scientific Article in Current Diabetes Reports Curr. Diab. Rep. 16:75 (2016)
Follicular helper T cells in autoimmunity.
2016 Scientific Article in Diabetes Diabetes 65, 2849-2861 (2016)
TGFβ contributes to impaired exercise response by suppression of mitochondrial key regulators in skeletal muscle.
2016 Scientific Article in Atherosclerosis Atherosclerosis 251, 164-169 (2016)
Beyond intima-media-thickness: Analysis of the carotid intima-media-roughness in a paediatric population.
2016 Scientific Article in Journal of the American Association for Laboratory Animal Science J. Amer. Assoc. Lab. Anim. Sci. 55, 375-386 (2016)
Clinical chemistry reference intervals for C57BL/6J, C57BL/6N, and C3HeB/FeJ mice (Mus musculus).
2016 Scientific Article in Nature Communications Nat. Commun. 7:11869 (2016)
The necroptosis-inducing kinase RIPK3 dampens adipose tissue inflammation and glucose intolerance.
2016 Scientific Article in Scientific Reports Sci. Rep. 6:27887 (2016)
Complement gene variants in relation to autoantibodies to beta cell specific antigens and type 1 diabetes in the TEDDY study.
2016 Scientific Article in Diabetes Care Diabetes Care 39, 1535-1542 (2016)
Reversion of β-cell autoimmunity changes risk of type 1 diabetes: TEDDY study.
2016 Other: News Item in Cell Metabolism Cell Metab. 23, 959-960 (2016)
Opposing effects of antidiabetic interventions on malignant growth and metastasis.
2016 Scientific Article in Thyroid Thyroid 26, 1131-1140 (2016)
Primary cell culture systems for human thyroid studies.
2016 Scientific Article in Diabetes Care Diabetes Care 39, 1311-1317 (2016)
Neuronal food reward activity in patients with type 2 diabetes with improved glycemic control after bariatric surgery.
2016 Scientific Article in Scientific Reports Sci. Rep. 6:26745 (2016)
Relationship of serum trimethylamine n-oxide (TMAO) levels with early atherosclerosis in humans.
2016 Scientific Article in Arteriosclerosis, Thrombosis, and Vascular Biology Arterioscler. Thromb. Vasc. Biol. 36, 1534-1548 (2016)
Activation of peroxisome proliferator-activated receptor-δ as novel therapeutic strategy to prevent in-stent restenosis and stent thrombosis.
2016 Meeting abstract in Cancer Research Cancer Res. 76:P1-06-02 (2016)
A force-sensitive organoid assay to quantify regenerative potential of single primary human mammary cells.
2016 Other: Opinion in Molecular Metabolism Mol. Metab. 5, 435-436 (2016)
Unforeseen role for glucocorticoids in combinatorial anti-obesity pharmacology.
2016 Scientific Article in Diabetes Diabetes 65, 2540-2552 (2016)
Bezafibrate improves insulin sensitivity and metabolic flexibility in STZ-treated diabetic mice.
2016 Nature Communications Nat. Commun. 7:11835 (2016)
Erratum: Myoscape controls cardiac calcium cycling and contractility via regulation of L-type calcium channel surface expression.
2016 Scientific Article in Mammalian Genome Mamm. Genome 27, 445-450 (2016)
INFRAFRONTIER: A European resource for studying the functional basis of human disease.
2016 Scientific Article in Endocrinology Endocrinology 157, 3157-3166 (2016)
Morphology, biochemistry and pathophysiology of MENX-related pheochromocytoma recapitulate the clinical features.
2016 Scientific Article in Obesity Facts Obes. Facts 9, 174-181 (2016)
FTO genotype interacts with improvement in aerobic fitness on body weight loss during lifestyle intervention.
2016 Scientific Article in Diabetes, Stoffwechsel und Herz Diabetes Stoffwechs. Herz 25, 79-83 (2016)
Kinder mit Frühstadium des Typ-1-Diabetes: Drei Fallberichte aus der Fr1da-Studie.
2016 Editorial in Clinical Gastroenterology and Hepatology Clin. Gastroenterol. Hepatol. 14, 1345-1346 (2016)
Nonalcoholic fatty liver disease and coronary artery calcification.
2016 Scientific Article in Diabetologia Diabetologia 59, 1973-1976 (2016)
Tetraspanin 7 autoantibodies in type 1 diabetes.
2016 Scientific Article in Review of Diabetic Studies, The Rev. Diabet. Stud. 12, 363-376 (2016)
Pharmacogenetics: Implications for modern type 2 diabetes therapy.
2016 Scientific Article in Cancer Research Cancer Res. 76, 3644-3654 (2016)
Increased expression of miR-23a mediates a loss of expression in the RAF kinase inhibitor protein RKIP.
2016 Scientific Article in Human Molecular Genetics Hum. Mol. Genet., DOI: 10.1093/hmg/ddw121 (2016)
Early hypermethylation of hepatic Igfbp2 results in its reduced expression preceding fatty liver in mice.
2016 Scientific Article in BMJ Open BMJ Open 6:e011144 (2016)
Capillary blood islet autoantibody screening for identifying pre-type 1 diabetes in the general population: Design and initial results of the Fr1da study.
2016 Scientific Article in Steroids Steroids 114, 7-15 (2016)
There goes the neighborhood: Assembly of transcriptional complexes during the regulation of metabolism and inflammation by the glucocorticoid receptor.
2016 Scientific Article in Lancet Diabetes and Endocrinology Lancet Diabet. Endocrinol. 4, 789-798 (2016)
Phenotypes of prediabetes and stratification of cardiometabolic risk.
2016 Scientific Article in Gut (eGut) Gut 66, 1369-1381 (2016)
Lymphotoxin β receptor signalling executes Helicobacter pylori-driven gastric inflammation in a T4SS-dependent manner.
2016 Scientific Article in Analytical and Bioanalytical Chemistry Anal. Bioanal. Chem. 408, 4683-4691 (2016)
1H NMR-based metabolite profiling workflow to reduce inter-sample chemical shift variations in urine samples for improved biomarker discovery.
2016 Scientific Article in Magnetic Resonance in Medicine Magn. Reson. Med. 75, 1391-1401 (2016)
A fully automatic reference deconvolution strategy to increase the accuracy of in vivo lipid signal quantification.
2016 Scientific Article in Neuropsychopharmacology Neuropsychopharmacology 41, 1551-1559 (2016)
Dopamine depletion reduces food-related reward activity independent of BMI.
2016 Scientific Article in Scientific Reports Sci. Rep. 6:24631 (2016)
Perturbed rhythmic activation of signaling pathways in mice deficient for Sterol Carrier Protein 2-dependent diurnal lipid transport and metabolism.
2016 Scientific Article in Molecular Metabolism Mol. Metab. 5, 321-327 (2016)
High density lipoprotein and metabolic disease: Potential benefits of restoring its functional properties.
2016 Scientific Article in EMBO Molecular Medicine EMBO Mol. Med. 8, 654-669 (2016)
Fasting-induced liver GADD45β restrains hepatic fatty acid uptake and improves metabolic health.
2016 Scientific Article in Cardiovascular Diabetology Cardiovasc. Diabetol. 15:72 (2016)
Achievement of treatment goals for secondary prevention of myocardial infarction or stroke in 29,325 patients with type 2 diabetes: A German/Austrian DPV-multicenter analysis.
2016 Scientific Article in JAMA: Journal of the American Medical Association JAMA 315, 1899-1901 (2016)
Infections in early life and development of type 1 diabetes.
2016 Scientific Article in Proceedings of the National Academy of Sciences of the United States of America Proc. Natl. Acad. Sci. U.S.A. 113, 5754-5759 (2016)
PI3K-resistant GSK3 controls adiponectin formation and protects from metabolic syndrome.
2016 Scientific Article in Science Signaling Sci. Signal. 9:ra43 (2016)
Identification of GPR83 as the receptor for the neuroendocrine peptide PEN.
2016 Scientific Article in Microbiome Microbiome 4:17 (2016)
Towards a functional hypothesis relating anti-islet cell autoimmunity to the dietary impact on microbial communities and butyrate production.
2016 Scientific Article in PLoS ONE PLoS ONE 11:e0152996 (2016)
CIP2A promotes T-cell activation and immune response to Listeria monocytogenes infection.
2016 Scientific Article in PLoS ONE PLoS ONE 11:e0153990 (2016)
Effects of genetic loci associated with central obesity on adipocyte lipolysis.
2016 Scientific Article in Nature Communications Nat. Commun. 7:11317 (2016)
Myoscape controls cardiac calcium cycling and contractility via regulation of L-type calcium channel surface expression.
2016 Meeting abstract in Experimental Dermatology Exp. Dermatol. 25, E16 (2016)
The impact of gliding on the prevalence of non-melanoma skin cancer and its precursors - a cross-sectional study among male pilots of glider aircrafts in Bavaria.
2016 Meeting abstract in Diabetes Technology & Therapeutics Diabetes Technol. Ther. 18, A31 (2016)
Switching to insulin glargine 300 U/ML (GLA-300): Benefits vs GLA-100 by duration of prior basal insulin therapy.
2016 Review in Current Opinion in Behavioral Sciences Curr. Opin. Behav. Sci. 9, 126-135 (2016)
Dietary triglycerides as signaling molecules that influence reward and motivation.
2016 Scientific Article in PLoS ONE PLoS ONE 11:e0152476 (2016)
Identification of non-HLA genes associated with celiac disease and country-specific differences in a large, international pediatric cohort.
2016 Scientific Article in Molecular Metabolism Mol. Metab. 5, 305-316 (2016)
Granulocyte Colony-Stimulating Factor (G-CSF): A saturated fatty acid-induced myokine with insulin-desensitizing properties in humans.
2016 Recension in Molecular Metabolism Mol. Metab. 5, 253-254 (2016)
Insulin receptor trafficking steers insulin action.
2016 Review in Trends in Molecular Medicine Trends Mol. Med. 22, 359-376 (2016)
Reappraisal of GIP pharmacology for metabolic diseases.
2016 Scientific Article in Cell Reports Cell Rep. 15, 360-371 (2016)
An essential role for liver ERα in coupling hepatic metabolism to the reproductive cycle.
2016 Scientific Article in American Journal of Clinical Nutrition Am. J. Clin. Nutr. 103, 1472-1481 (2016)
Reduction of the n-6:n-3 long-chain PUFA ratio during pregnancy and lactation on offspring body composition: Follow-up results from a randomized controlled trial up to 5 y of age.
2016 Scientific Article in Ecology and Evolution Ecol. Evol. 6, 2516-2535 (2016)
Diversification and coevolution of the ghrelin/growth hormone secretagogue receptor system in vertebrates.
2016 Scientific Article in PLoS ONE PLoS ONE 11:e0150472 (2016)
Generation and standardized, systemic phenotypic analysis of Pou3f3L423P mutant mice.
2016 Meeting abstract in Diabetic Medicine Diabetic Med. 33, 76-77 (2016)
Is there regulation of the autoimmune response in slow progressors to type 1 diabetes?
2016 Letter to the Editor in Epidemiology Epidemiology 27, E26-E28 (2016)
Response to: Ambient air pollution is not associated with early manifestation of type 1 diabetes.
2016 Review in Diabetologia Diabetologia 59, 920-927 (2016)
Renaissance of leptin for obesity therapy.
2016 Meeting abstract in Transgenic Research Transgenic Res. 25, 228 (2016)
EMMA: The European Mouse Mutant Archive.
2016 Scientific Article in Diabetes Diabetes 65, 1988-1995 (2016)
Growth and risk for islet autoimmunity and progression to type 1 diabetes in early childhood: The Environmental Determinants of Diabetes in the Young Study.
2016 Scientific Article in Cell Death and Differentiation Cell Death Differ. 23, 1026-1037 (2016)
Immunoproteasome dysfunction augments alternative polarization of alveolar macrophages.
2016 Scientific Article in Science Signaling Sci. Signal. 9:rs1 (2016)
Mouse redox histology using genetically encoded probes.
2016 Review in Molecular Metabolism Mol. Metab. 5, 255-262 (2016)
Primary prevention of beta-cell autoimmunity and type 1 diabetes - the Global Platform for the Prevention of Autoimmune Diabetes (GPPAD) perspectives.
2016 Scientific Article in PLoS ONE PLoS ONE 11:e0151771 (2016)
miTALOS v2: Analyzing tissue specific microRNA function.
2016 Scientific Article in Nature Communications Nat. Commun. 7:10991 (2016)
Type 1 diabetes vaccine candidates promote human Foxp3+Treg induction in humanized mice.
2016 Scientific Article in Nature Genetics Nat. Genet. 48, 497-499 (2016)
Epigenetic germline inheritance of diet-induced obesity and insulin resistance.
2016 Scientific Article in Nature Communications Nat. Commun. 7:10782 (2016)
Hypothalamic leptin action is mediated by histone deacetylase 5.
2016 Scientific Article in Prostaglandins, Leukotrienes and Essential Fatty Acids Prostaglandins Leukot. Essent. Fatty Acids 110, 55-61 (2016)
Contribution of glycerophospholipids and sphingomyelin to the circulating NEFA.
2016 Scientific Article in Scientific Reports Sci. Rep. 6:22540 (2016)
Novel small molecules targeting ciliary transport of smoothened and oncogenic Hedgehog pathway activation.
2016 Scientific Article in Scientific Reports Sci. Rep. 6:22218 (2016)
Muscle and liver-specific alterations in lipid and acylcarnitine metabolism after a single bout of exercise in mice.
2016 Scientific Article in Scientific Reports Sci. Rep. 6:21107 (2016)
Purity matters: A workflow for the valid high-resolution lipid profiling of mitochondria from cell culture samples.
2016 Scientific Article in Human Molecular Genetics Hum. Mol. Genet. 25, 2082-2092 (2016)
Testing the role of predicted gene knockouts in human anthropometric trait variation.
2016 Scientific Article in Journal of Steroid Biochemistry and Molecular Biology, The J. Steroid Biochem. Mol. Biol. 159, 60-69 (2016)
Altered levels of acylcarnitines, phosphatidylcholines, and sphingomyelins in peritoneal fluid from ovarian endometriosis patients.
2016 Scientific Article in Hawai'i Journal of Medicine & Public Health Hawaii J. Med. Public Health 75, 35-41 (2016)
Acculturation is not related to physical activity stage of change for children in Hawai'i.
2016 Editorial in Diabetes Diabetes 65, 551-553 (2016)
Hypothalamic injury: Fish oil to the rescue!
2016 Scientific Article in PLoS ONE PLoS ONE 11:e0149477 (2016)
Pitchfork and Gprasp2 target smoothened to the primary cilium for Hedgehog pathway activation.
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Assays for insulin and insulin-like metabolic activity based on hepatocytes, myocytes and diaphragms.
In: Hock, F.J.* [Eds.]: Drug Discovery and Evaluation: Pharmacological Assays. Cham, Switzerland: Springer, 2016. 2657-2679
Measurement of insulin and other glucose-regulating peptide hormones.
In: Hock, F.J.* [Eds.]: Drug Discovery and Evaluation: Pharmacological Assays. Cham, Switzerland: Springer, 2016. 3071-3117
Monitoring of diabetic late complication.
In: Hock, F.J.* [Eds.]: Drug Discovery and Evaluation: Pharmacological Assays. Cham, Switzerland: Springer, 2016. 3167-3284
Personalized diagnosis and therapy.
In: Hock, F.J.* [Eds.]: Drug Discovery and Evaluation: Pharmacological Assays. Cham, Switzerland: Springer, 2016. 2871-2893
Assays for insulin and Insulin-like regulation of energy metabolism.
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Insulin analogs: Assessment of insulin mitogenicity and IGF-I activity.
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Insulin target tissues and cells.
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Assays for insulin and insulin-like activity based on adipocytes.
In: Hock, F.J.* [Eds.]: Drug Discovery and Evaluation: Pharmacological Assays. Cham, Switzerland: Springer, 2016. 2623-2656
Measurement of blood glucose-lowering and antidiabetic activity.
In: Hock, F.J.* [Eds.]: Drug Discovery and Evaluation: Pharmacological Assays. Cham, Switzerland: Springer, 2016. 2895-2934
Assays for insulin and insulin-like regulation of gene and protein expression.
In: Hock, F.J.* [Eds.]: Drug Discovery and Evaluation: Pharmacological Assays. Cham, Switzerland: Springer, 2016. 3059-3070
Measurement of glucose absorption.
In: Hock, F.J.* [Eds.]: Drug Discovery and Evaluation: Pharmacological Assays. Cham, Switzerland: Springer, 2016. 2569-2581
Methods to induce experimental Diabetes Mellitus.
In: Hock, F.J.* [Eds.]: Drug Discovery and Evaluation: Pharmacological Assays. Cham, Switzerland: Springer, 2016. 2583-2622
Genetically diabetic animals.
In: Hock, F.J.* [Eds.]: Drug Discovery and Evaluation: Pharmacological Assays. Cham, Switzerland: Springer, 2016. 2935-3028
Assays for insulin and insulin-like signal transduction based on adipocytes, hepatocytes and myocytes.
In: Hock, F.J.* [Eds.]: Drug Discovery and Evaluation: Pharmacological Assays. Cham, Switzerland: Springer, 2016. 3029-3057
Assays for the expression and release of insulin and glucose-regulating peptide hormones from pancreatic β-cell.
2016 Scientific Article in PLoS Pathogens PLoS Pathog. 12:e1005405 (2016)
A viral microRNA cluster regulates the expression of PTEN, p27 and of a bcl-2 homolog.
2016 Review in Neurobiology of Learning and Memory Neurobiol. Learn. Mem. 129, 50-59 (2016)
Coordinating different representations in the hippocampus.
2016 Review in Endocrine Endocrine 51, 390-401 (2016)
Exercise and diabetes: Relevance and causes for response variability.
2016 Scientific Article in Journal of Breath Research J. Breath Res. 10:016009 (2016)
Diet-induced and mono-genetic obesity alter volatile organic compound signature in mice.
2016 Scientific Article in American Journal of Physiology - Renal Physiology Am. J. Physiol.-Renal Physiol. 310, F785-F795 (2016)
Oxalate-induced chronic kidney disease with its uremic and cardiovascular complications in C57BL/6 mice.
2016 Scientific Article in Molecular Metabolism Mol. Metab. 5, 283-295 (2016)
Mitochondrial gene polymorphisms alter hepatic cellular energy metabolism and aggravate diet-induced non-alcoholic steatohepatitis.
2016 Scientific Article in Molecular Metabolism Mol. Metab. 5, 47-56 (2016)
Incretin-like effects of small molecule trace amine-associated receptor 1 agonists.
2016 Scientific Article in Cardiovascular Diabetology Cardiovasc. Diabetol. 15:21 (2016)
Interleukin-6 predicts inflammation-induced increase of glucagon-like peptide-1 in humans in response to cardiac surgery with association to parameters of glucose metabolism.
2016 Scientific Article in Journal of Inherited Metabolic Disease J. Inherit. Metab. Dis. 39, 309-319 (2016)
Mildly compromised tetrahydrobiopterin cofactor biosynthesis due to Pts variants leads to unusual body fat distribution and abdominal obesity in mice.
2016 Scientific Article in Haematologica - The Hematology Journal Haematologica 101, e48-e51 (2016)
Iron deficiency anemia in cyclic GMP kinase knockout mice.
2016 Scientific Article in Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids Biochim. Biophys. Acta-Mol. Cell Biol. Lipids 1861, 285-293 (2016)
IP-receptor and PPARs trigger the conversion of human white to brite adipocyte induced by carbaprostacyclin.
2016 Scientific Article in Lancet Diabetes and Endocrinology Lancet Diabet. Endocrinol. 4, 457-467 (2016)
Divergent associations of height with cardiometabolic disease and cancer: Epidemiology, pathophysiology, and global implications.
2016 Scientific Article in EMBO Reports EMBO Rep. 17, 455-469 (2016)
Life span extension by targeting a link between metabolism and histone acetylation in Drosophila.
2016 Editorial in Cell Cell 164, 341-342 (2016)
Epigenetic ON/OFF switches for obesity.
2016 Scientific Article in PLoS ONE PLoS ONE 11:e0145563 (2016)
Glucose-raising polymorphisms in the human clock gene Cryptochrome 2 (CRY2) affect hepatic lipid content.
2016 Scientific Article in Mammalian Genome Mamm. Genome 27, 111-121 (2016)
Exome sequencing identifies a nonsense mutation in Fam46a associated with bone abnormalities in a new mouse model for skeletal dysplasia.
2016 Scientific Article in Journal of Diabetes Research J. Diabetes Res. 2016:4208156 (2016)
Longitudinal frequencies of blood leukocyte sub-populations differ between NOD and NOR mice, but do not predict diabetes in NOD mice.
2016 Scientific Article in Journal of Diabetes Research J. Diabetes Res. 2016:2720650 (2016)
Participant experiences in The Environmental Determinants of Diabetes in the Young study: Common reasons for withdrawing.
2016 Review in European Journal of Preventive Cardiology Eur. J. Prev. Cardiol. 23, 956-966 (2016)
Metabolically healthy obesity and cardiovascular events: A systematic review and meta-analysis.
2016 Scientific Article in Journal of Proteomics J. Proteomics 133, 66-75 (2016)
Liver lipid metabolism is altered by increased circulating estrogen to androgen ratio in male mouse.
2016 Scientific Article in Clinical Gastroenterology and Hepatology Clin. Gastroenterol. Hepatol. 14, 403-409 (2016)
Effects of gluten intake on risk of celiac disease: A case-control study on a Swedish birth cohort.
2016 Scientific Article in Molecular Metabolism Mol. Metab. 5, 79-90 (2016)
Muscle mitochondrial stress adaptation operates independently of endogenous FGF21 action.
2016 Scientific Article in Basic Research in Cardiology Basic Res. Cardiol. 111:6 (2016)
Knock-out of nexilin in mice leads to dilated cardiomyopathy and endomyocardial fibroelastosis.
2016 Scientific Article in Nucleic Acids Research Nucleic Acids Res. 44, 1326-1341 (2016)
The expression of a viral microRNA is regulated by clustering to allow optimal B cell transformation.
2016 Scientific Article in Cell Stem Cell Cell Stem Cell 18, 396-409 (2016)
Identification and successful negotiation of a metabolic checkpoint in direct neuronal repogramming.
2016 Scientific Article in Journal of Proteome Research J. Proteome Res. 15, 554-562 (2016)
Diagnostic and prognostic metabolites identified for joint symptoms in the KORA population.
2016 Scientific Article in JAMA Pediatrics JAMA Pediatr. 170, 20-28 (2016)
Association of early exposure of probiotics and islet autoimmunity in the TEDDY study.
2016 Scientific Article in Journal of Biological Chemistry, The J. Biol. Chem. 291, 913-923 (2016)
Deletion of monoglyceride lpase in astrocytes attenuates lipopolysaccharide-induced neuroinflammation.
2016 Scientific Article in Nucleic Acids Research Nucleic Acids Res. 44, D286-D293 (2016)
eggNOG 4.5: A hierarchical orthology framework with improved functional annotations for eukaryotic, prokaryotic and viral sequences.
2016 Scientific Article in Mechanisms of Development Mech. Dev. 139, 51-64 (2016)
The global gene expression profile of the secondary transition during pancreatic development.
2016 Scientific Article in Molecular Metabolism Mol. Metab. 5, 67-78 (2016)
Ataxin-10 is part of a cachexokine cocktail triggering cardiac metabolic dysfunction in cancer cachexia.
2016 Scientific Article in Acta Diabetologica Acta Diabetol. 53, 433-437 (2016)
Development of a simple tool to predict the risk of postpartum diabetes in women with gestational diabetes mellitus.
2016 Scientific Article in Neuropsychopharmacology Neuropsychopharmacology 41, 1540-1550 (2016)
Central nervous insulin signaling in sleep-associated memory formation and neuroendocrine regulation.
2016 Scientific Article in Clinical Science Clin. Sci. 130, 273-287 (2016)
Metabolomics screening identifies reduced L-carnitine to be associated with progressive emphysema.
2016 Scientific Article in Journal of the American Society of Nephrology J. Am. Soc. Nephrol. 27, 1175-1188 (2016)
A metabolome-wide association study of kidney function and disease in the general population.
2016 Scientific Article in Public Health Nutrition Public Health Nutr. 19, 804-813 (2016)
Factors associated with longitudinal food record compliance in a paediatric cohort study.
2016 Scientific Article in Handbook of Experimental Pharmacology Handb. Exp. Pharmacol. 233, 437-459 (2016)
Current and emerging treatment options in diabetes care.
2016 Scientific Article in Journal of Public Mental Health J. Public Health 38, 163-169 (2016)
Mobile phone use and willingness to pay for SMS for diabetes in Bangladesh.
2016 Scientific Article in Pediatric Diabetes Pediatr. Diabetes 17, 191-198 (2016)
Vascular risk factors in children, adolescents, and young adults with type 1 diabetes complicated by celiac disease: Results from the DPV initiative.
2016 Scientific Article in Gut (eGut) Gut 65, 647-657 (2016)
A subset of metastatic pancreatic ductal adenocarcinomas depends quantitatively on oncogenic Kras/Mek/Erk-induced hyperactive mTOR signalling.
2015 Letter to the Editor in Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet. 123, 296-298 (2015)
Human islets exhibit electrical activity on microelectrode arrays (MEA).
2015 Scientific Article in Diabetes, Obesity and Metabolism Diabetes Obes. Metab. 17, 170-178 (2015)
Comparison of insulin glargine and liraglutide added to oral agents in patients with poorly controlled type 2 diabetes.
2015 Scientific Article in PLoS ONE PLoS ONE 10:e0134971 (2015)
Diabetes mellitus and prediabetes on kidney transplant waiting list- prevalence, metabolic phenotyping and risk stratification approach.
2015 Scientific Article in Diabetic Medicine Diabetic Med. 32, 1555-1567 (2015)
Empagliflozin as add-on to metformin in people with Type 2 diabetes.
2015 Scientific Article in Journal of cell communication and signaling J. Cell Commun. Signal. 9, 143-150 (2015)
Gender-specific effects on food intake but no inhibition of age-related fat accretion in transgenic mice overexpressing human IGFBP-2 lacking the Cardin-Weintraub sequence motif.
2015 Scientific Article in PLoS ONE PLoS ONE 10, DOI: 10.1371/journal.pone.0144494 (2015)
Variation in the phosphoinositide 3-kinase gamma gene affects plasma HDL-cholesterol without modification of metabolic or inflammatory markers.
2015 Scientific Article in Nature Reviews - Endocrinology Nat. Rev. Endocrinol. 11, 701-711 (2015)
Impaired insulin action in the human brain: Causes and metabolic consequences.
2015 Scientific Article in NeuroImage - a Journal of Brain Function Neuroimage 124, 806-812 (2015)
Meta-analysis of real-time fMRI neurofeedback studies using individual participant data: How is brain regulation mediated?
2015 Scientific Article in Molecular Metabolism Mol. Metab. 4, 971-976 (2015)
Dissociation of GLP-1 and insulin association with food processing in the brain: GLP-1 sensitivity despite insulin resistance in obese humans.
2015 Scientific Article in Methods in Molecular Biology Methods Mol. Biol. 1265, 415-424 (2015)
A cybrid cell model for the assessment of the link between mitochondrial deficits and sporadic Parkinson's disease.
2015 Scientific Article in Methods in Molecular Biology Methods Mol. Biol. 1264, 321-329 (2015)
Prediction of mitochondrial protein function by comparative physiology and phylogenetic profiling.
München, Technische Universität, Fakultät für Medizin, Diss., 2015, 152 S.
Factors that influence age of type 1 diabetes onset and beta cell function in children and adults with newly diagnosed type 1 diabetes.
München, Technische Universität, Fakultät Wissenschaftszentrum Weihenstephan, Diss., 2015, 140 S.
Regulation of myokines in exercising human skeletal muscle cells obtained from phenotyped donors.
2015 Scientific Article EASD Kongress 2015 (2015)
Novel phenotypes of prediabetes?
2015 Meeting abstract in Annals of Nutrition and Metabolism Ann. Nutr. Metab. 67, 413 (2015)
Long-chain polyunsaturated fatty acids during pregnancy/lactation and children's body composition: 5-year follow-up data (INFAT-study).
2015 Scientific Article in Journal of Global Health J. Glob. Health 5, 98-106 (2015)
Association between depression and diabetes amongst adults in Bangladesh: Hospital-based case-control study.
2015 Meeting abstract in Allergy Allergy 70, 459-460 (2015)
Local inhibition of IL-4-and IL-13-mediated signaling as adjuvant for tolerance induction during allergen-specific immunotherapy.
2015 Scientific Article in Epidemiology Epidemiology 26, e31-e32 (2015)
Ambient air pollution and early manifestation of type 1 diabetes.
2015 Scientific Article in Archives of Physiology and Biochemistry Arch. Physiol. Biochem. 121, 194-205 (2015)
Identification of novel putative adipomyokines by a cross-species annotation of secretomes and expression profiles.
2015 Scientific Article in Genes and Nutrition Genes Nutr. 10:57 (2015)
Skeletal muscle mitochondrial uncoupling prevents diabetes but not obesity in NZO mice, a model for polygenic diabesity.
2015 Letter to the Editor in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 100, L102-L103 (2015)
Letter to the editor: Comment on "FGF21 response to critical illness: Effect of blood glucose control and relation with cellular stress and survival" by Thiessen S.E., et al.
2015 Scientific Article in Journal of Virology J. Virol. 89, 857-862 (2015)
Malawi polyomavirus is a prevalent human virus that interacts with known tumor suppressors.
2015 Scientific Article in Forschung Medizin - Exzellenzforschung in der Medizin For. Med. Exz. Med. 5, 43-47 (2015)
Diabetes mellitus: Zelluläre Plastizität und Perspektiven für die regenerative Therapie.
2015 Scientific Article in Archives of Biochemistry and Biophysics Arch. Biochem. Biophys. 589, 145-151 (2015)
A single night of sleep curtailment increases plasma acylcarnitines: Novel insights in the relationship between sleep and insulin resistance.
2015 Scientific Article in Mammalian Genome Mamm. Genome 27, 17-28 (2015)
Dexamethasone treatment alters insulin, leptin, and adiponectin levels in male mice as observed in DIO but does not lead to alterations of metabolic phenotypes in the offspring.
2015 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 100, 4029-4036 (2015)
Gestational diabetes impairs human fetal postprandial brain activity.
2015 Scientific Article in NeuroImage - a Journal of Brain Function Neuroimage 125, 36-44 (2015)
Specific white matter tissue microstructure changes associated with obesity.
2015 Scientific Article in PLoS ONE PLoS ONE 10:e0140161 (2015)
Residual upper arm motor function primes innervation of paretic forearm muscles in chronic stroke after Brain-Machine Interface (BMI) training.
2015 Scientific Article in Journal of Neuroendocrinology J. Neuroendocrinol. 27, 872-886 (2015)
Effect of deletion of ghrelin-o-acyltransferase on the pulsatile release of growth hormone in mice.
2015 Meeting abstract in Oncology Research and Treatment Oncol. Res. Treat. 38, 99 (2015)
Loss of the tumor- and metastasis suppressor RAF kinase inhibitor protein is caused by the overexpression of miRNA-23a.
2015 Scientific Article in Biochemical Journal / Reviews Biochem. J., DOI: 10.1042/BJ20151080 (2015)
Palmitate-induced impairment of glucose-stimulated insulin secretion precedes mitochondrial dysfunction in mouse pancreatic islets.
2015 Scientific Article in Frontiers in Behavioral Neuroscience Front. Behav. Neurosci. 9:302 (2015)
Conditional reduction of adult born doublecortin-positive neurons reversibly impairs selective behaviors.
2015 Scientific Article in Current Protocols of Mouse Biology Curr. Protoc. Mouse Biol. 5, 291-301:doi: 10.1002/9780470942390.mo160 (2015)
Tests for anxiety-related behavior in mice.
2015 Scientific Article in Current Protocols of Mouse Biology Curr. Protoc. Mouse Biol. 5, 331-358:doi: 10.1002/9780470942390.mo160 (2015)
Assessing cognition in mice.
2015 Meeting abstract in European Journal of Neurology Eur. J. Neurol. 22, 30 (2015)
Familial dyskinesia with facial myokymia due to ADCY5 mutation: Treatment with propranolol.
2015 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 100, E1568–E1574 (2015)
The genetic variant I148M in PNPLA3 is associated with increased hepatic retinyl-palmitate storage in humans.
2015 Scientific Article in Nutrition Journal Nutr. J. 14:117 (2015)
Ketoacidosis in a non-diabetic woman who was fasting during lactation.
2015 Scientific Article in Arteriosclerosis, Thrombosis, and Vascular Biology Arterioscler. Thromb. Vasc. Biol. 36, 122-133 (2015)
MFAP4 promotes vascular smooth muscle migration, proliferation and accelerates neointima formation.
2015 Scientific Article in Genetic Epidemiology Genet. Epidemiol. 39, 499-508 (2015)
Evaluating the calibration and power of three gene-based association tests of rare variants for the X chromosome.
2015 Scientific Article in Frontiers in Behavioral Neuroscience Front. Behav. Neurosci. 9:302 (2015)
Conditional reduction of adult born doublecortin-positive neurons reversibly impairs selective behaviors.
2015 Scientific Article in Journal of Pediatric Psychology J. Pediatr. Psychol., DOI: 10.1093/jpepsy/jsv092 (2015)
Predicting later study withdrawal in participants active in a longitudinal birth cohort study for 1 year: The TEDDY study.
2015 Scientific Article in American Journal of Clinical Nutrition Am. J. Clin. Nutr. 102, 1216-1221 (2015)
Gluten consumption during late pregnancy and risk of celiac disease in the offspring: The TEDDY birth cohort.
2015 Scientific Article in Deutsche Medizinische Wochenschrift - DMW Dtsch. Med. Wochenschr. 140, 1278-1283 (2015)
Kurzer, gestörter und unregelmäßiger Schlaf: Die schädlichen Auswirkungen auf den menschlichen Stoffwechsel.
2015 Scientific Article in Cellular & Molecular Biology Letters Cell. Mol. Biol. Lett. 20, 773-787 (2015)
Homology arms of targeting vectors for gene insertions and Crispr/Cas9 technology: Size does not matter; quality control of targeted clones does.
2015 Scientific Article in Molecular Metabolism Mol. Metab. 4, 406-417 (2015)
Mice lacking neutral amino acid transporter B0AT1 (Slc6a19) have elevated levels of FGF21 and GLP-1 and improved glycaemic control.
2015 Scientific Article in Journal of Diabetes Research J. Diabetes Res.:842584 (2015)
A glyoxalase-1 knockdown does not have major short term effects on energy expenditure and atherosclerosis in mice.
2015 Scientific Article in BMC Infectious Diseases BMC Infect. Dis. 15, 464 (2015)
Urinary Neutrophil Gelatinase-Associated Lipocalin (NGAL) and proteinuria predict severity of acute kidney injury in Puumala virus infection.
2015 Scientific Article in Hormone and Metabolic Research Horm. Metab. Res. 48, 16-19 (2015)
Risk stratification in women with gestational diabetes according to and beyond current WHO criteria.
2015 Scientific Article in Maternal & Child Nutrition Matern. Child Nutr. 11, 803-814 (2015)
Age at first introduction to complementary foods is associated with sociodemographic factors in children with increased genetic risk of developing type 1 diabetes.
2015 Scientific Article in PLoS Genetics PLoS Genet. 11:e1005561 (2015)
PPP2R5C couples hepatic glucose and lipid homeostasis.
In: Han, D.* ; Kaplowitz, N.* [Eds.]: Mitochondria in Liver Disease. Boca Raton, FL: CRC Press, 2015. 383-412
Mitochondrial function, dysfunction, and adaption in the liver during the development of diabetes.
2015 Scientific Article in Molecular Metabolism Mol. Metab. 4, 823-833 (2015)
The calcineurin-NFAT pathway controls activity-dependent circadian gene expression in slow skeletal muscle.
2015 Editorial in Sleep Sleep 38, 1341-1342 (2015)
Sleep, don't sneeze: Longer sleep reduces the risk of catching a cold.
2015 Meeting abstract in FEBS Journal, The FEBS J. 282, 274-275 (2015)
Biosensing of intact glycosylphosphatidylinositol-anchored proteins in serum as biomarkers for stress-induced diseases.
2015 Meeting abstract in Biophysical Journal Biophys. J. 108, 189A (2015)
Systems approaches to mitochondrial calcium signaling.
2015 Scientific Article in Diabetes Diabetes 65, 406-420 (2015)
Obesity in MENX rats is accompanied by high circulating levels of ghrelin and improved insulin sensitivity.
2015 Scientific Article in Cellular Physiology and Biochemistry Cell. Physiol. Biochem. 37, 1474-1490 (2015)
Endothelin-1 overexpression improves renal function in eNOS knockout mice.
2015 Scientific Article in Nature Communications Nat. Commun. 6:8054 (2015)
Tbx15 controls skeletal muscle fibre-type determination and muscle metabolism.
2015 Scientific Article in Development / Company of Biologists Development 142, 3519-3528 (2015)
Revising the embryonic origin of thyroid C cells in mice and humans.
2015 Editorial in Archives of Biochemistry and Biophysics Arch. Biochem. Biophys. 589, 1-3 (2015)
Guest editorial: Special issue on metabolomics.
2015 Meeting abstract in European Heart Journal Eur. Heart J. 36, 692 (2015)
Targeting the nuclear receptor PPARdelta as novel strategy to prevent in-stent restenosis and stent thrombosis.
2015 Meeting abstract in Alcohol and Alcoholism Alcohol Alcohol. 50:SY14-4 (2015)
Primary hepatocellular damage and suppressed fat mobilization in heavy drinkers with PNPLA3 G genotype.
2015 Meeting abstract in Nephrology Dialysis Transplantation Nephrol. Dial. Transplant. 30:SP045 (2015)
Detailed morphological analyses of a novel mouse model of site-specific glomerular thrombotic microangiopathy.
2015 Scientific Article in Human Molecular Genetics Hum. Mol. Genet. 24, 7286-7294 (2015)
Overexpression of the mitochondrial methyltransferase TFB1M in the mouse does not impact mitoribosomal methylation status of hearing.
2015 Scientific Article in Diabetes Care Diabetes Care 38, 1964-1974 (2015)
Staging presymptomatic type 1 diabetes: A scientific statement of JDRF, the Endocrine Society, and the American Diabetes Association.
2015 Scientific Article in Diabetologia Diabetologia 58, 2877-2884 (2015)
A high-risk phenotype associates with reduced improvement in glycaemia during a lifestyle intervention in prediabetes.
2015 Scientific Article in Diabetologia Diabetologia 58, 2819-2831 (2015)
Protein kinase Cδ regulates nuclear export of FOXO1 through phosphorylation of the chaperone 14-3-3ζ.
2015 Scientific Article in Nature Communications Nat. Commun. 6:8261 (2015)
eIF6 coordinates insulin sensitivity and lipid metabolism by coupling translation to transcription.
2015 Scientific Article in RNA Biology RNA Biol. 12, 998-1009 (2015)
SimiRa: A tool to identify coregulation between microRNAs and RNA-binding proteins.
Berlin: epubli GmbH, 2015, 156 S. (Zugl. München, Technische Universität, Fakultät Wissenschaftszentrum Weihenstephan, Diss., 2015)
Network-based analysis of genetic and nutritional effects on human metabolism.
2015 Scientific Article in Journal of Neuroscience J. Neurosci. 35, 13385-13401 (2015)
Dickkopf3 promotes the differentiation of a rostrolateral midbrain dopaminergic neuronal subset in vivo and from pluripotent stem cells in vitro in the mouse.
2015 Scientific Article in Cell Metabolism Cell Metab. 22, 838-850 (2015)
Calcineurin links mitochondrial elongation with energy metabolism.
2015 Scientific Article in Archives of Biochemistry and Biophysics Arch. Biochem. Biophys. 589, 93-107 (2015)
Metabolic switch during adipogenesis: From branched chain amino acid catabolism to lipid synthesis.
München, Technische Universität, Fakultät Wissenschaftszentrum Weihenstephan, Diss., 2015, 131 S.
Wirkung von Vitamin D3 auf die zellvermittelte Immunantwort bei der Pathogenese des Typ-1-Diabetes.
2015 Meeting abstract in Diabetologia Diabetologia 58, S45 (2015)
The hepatokine fetuin-A has TLR4 dependent and independent effects in islets.
2015 Meeting abstract in Diabetologia Diabetologia 58, S305 (2015)
Associations of glucagon-like peptide 1 with food processing in the brain are present in lean and obese humans.
2015 Meeting abstract in Diabetologia Diabetologia 58, S232 (2015)
Downregulation of TxNIP under glucolipotoxic conditions in insulin secreting cells.
2015 Meeting abstract in Diabetologia Diabetologia 58, S258 (2015)
Reduced and adverse metabolic response to supervised 8-week endurance exercise in a group at high risk for type 2 diabetes.
2015 Meeting abstract in Diabetologia Diabetologia 58, S142 (2015)
SNP x SNP interactions in the VPS13C/C2CD4A/C2CD4B locus modulate diabetes risk.
2015 Meeting abstract in Diabetologia Diabetologia 58, S228-S229 (2015)
Palmitate-induced impairment of glucose-stimulated insulin secretion by pancreatic beta cells is disconnected from concomitant mitochondrial respiratory defects.
2015 Scientific Article in Archives of Biochemistry and Biophysics Arch. Biochem. Biophys. 589, 152-157 (2015)
Physiological changes due to mild cooling in healthy lean males of white Caucasian and South Asian descent: A metabolomics study.
2015 Scientific Article in Molecular and Cellular Endocrinology Mol. Cell. Endocrinol. 417, 10-19 (2015)
Combination cannabinoid and opioid receptor antagonists improves metabolic outcomes in obese mice.
2015 Scientific Article in Frontiers in Endocrinology Front. Endocrin. 6:129 (2015)
Transcriptional pathways in cPGI2-induced adipocyte progenitor activation for browning.
2015 Scientific Article in PLoS Genetics PLoS Genet. 11:e1005506 (2015)
Identification of four mouse diabetes candidate genes altering β-cell proliferation.
2015 Scientific Article in American Journal of Physiology - Endocrinology and Metabolism Am. J. Physiol. Endocrinol. Metab. 309, E736-E746 (2015)
Alterations of plasma metabolite profiles related to adipose tissue distribution and cardiometabolic risk.
2015 Review in Physiology & Behavior Physiol. Behav. 152, 479-493 (2015)
Controversies in fat perception.
2015 Scientific Article in Current Protocols of Mouse Biology Curr. Protoc. Mouse Biol. 5, 205-222 (2015)
Exploration of energy metabolism in the mouse using indirect calorimetry: Measurement of Daily Energy Expenditure (DEE) and Basal Metabolic Rate (BMR).
2015 Scientific Article in Analytical Chemistry Anal. Chem. 87, 7698-7704 (2015)
Retention time prediction improves identification in nontargeted lipidomics approaches.
2015 Scientific Article in Molecular Pharmaceutics Mol. Pharm. 12, 2767-2780 (2015)
Intranasal neuropeptide administration to target the human brain in health and disease.
2015 Scientific Article in Molecular Metabolism Mol. Metab. 4, 732-740 (2015)
Molecular regulation of urea cycle function by the liver glucocorticoid receptor.
2015 Scientific Article in PLoS ONE PLoS ONE 10:e0133580 (2015)
Potential predictors of plasma fibroblast growth factor 23 concentrations: Cross-sectional analysis in the EPIC-Germany study.
2015 Editorial in BioMed Research International Biomed Res. Int. 2015:986742 (2015)
Interplay between the endocrine system and immune cells.
2015 Scientific Article in Cell Metabolism Cell Metab. 22, 516-530 (2015)
Interactions between gut microbiota, host genetics and diet modulate the predisposition to obesity and metabolic syndrome.
2015 Scientific Article in European Journal of Endocrinology Eur. J. Endocrinol. 173, 643-653 (2015)
Biomarkers of iron metabolism are independently associated with impaired glucose metabolism and type 2 diabetes: The KORA F4 Study.
2015 Scientific Article in Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet. 65, 622-626 (2015)
Gender-specific effects of treatment with lifestyle, metformin or sulfonylurea on glycemic control and body weight: A German multicenter analysis on 9108 patients.
2015 Scientific Article in Scientific Reports Sci. Rep. 5:13212 (2015)
The stool microbiota of insulin resistant women with recent gestational diabetes, a high risk group for type 2 diabetes.
2015 Scientific Article in Archives of Biochemistry and Biophysics Arch. Biochem. Biophys. 589, 138-144 (2015)
Type 2 diabetes is associated with postprandial amino acid measures.
2015 Scientific Article in Molecular Metabolism Mol. Metab. 4, 551-560 (2015)
Glucagon-to-insulin ratio is pivotal for splanchnic regulation of FGF-21 in humans.
2015 Scientific Article in PLoS ONE PLoS ONE 10:e0134503 (2015)
Cox4i2, Ifit2, and Prdm11 mutant mice: Effective selection of genes predisposing to an altered airway inflammatory response from a large compendium of mutant mouse lines.
2015 Scientific Article in Metabolomics Metabolomics 11, 1815-1833 (2015)
Gender-specific pathway differences in the human serum metabolome.
2015 Scientific Article in Development / Company of Biologists Development 142, 3009-3020 (2015)
Meis1 coordinates a network of genes implicated in eye development and microphthalmia.
2015 Scientific Article in Glia Glia 63, 2340-2361 (2015)
Astrocyte reactivity after brain injury - the role of galectins 1 and 3.
2015 Scientific Article in PLoS Genetics PLoS Genet. 11:e1005423 (2015)
SLIRP regulates the rate of mitochondrial protein synthesis and protects LRPPRC from degradation.
2015 Scientific Article in Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet. 123, 433-438 (2015)
Metabolic profiles during an oral glucose tolerance test in pregnant women with and without gestational diabetes.
2015 Scientific Article in Scientific Reports Sci. Rep. 5:12673 (2015)
Validated prediction of pro-invasive growth factors using a transcriptome-wide invasion signature derived from a complex 3D invasion assay.
2015 Scientific Article in Diabetes Care Diabetes Care 38, 1858-1867 (2015)
Effects of metformin on metabolite profiles and LDL cholesterol in patients with type 2 diabetes.
2015 Scientific Article in Analytical Chemistry Anal. Chem. 87, 8917-8924 (2015)
Solutions for low and high accuracy mass spectrometric data matching. A data-driven annotation strategy in non-targeted metabolomics.
2015 Scientific Article in Journal of Biological Chemistry, The J. Biol. Chem. 290, 20284-20294 (2015)
MiR-184 regulates pancreatic β-cell function according to glucose metabolism.
2015 Scientific Article in Nature Genetics Nat. Genet. 47, 969-978 (2015)
Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics.
2015 Scientific Article in Mammalian Genome Mamm. Genome 26, 467-481 (2015)
Principles and application of LIMS in mouse clinics.
2015 Scientific Article in Diabetes Care Diabetes Care 38, e112-e113 (2015)
Effects of mobile phone SMS to improve glycemic control among patients with type 2 diabetes in Bangladesh: A prospective, parallel-group, randomized controlled trial.
2015 Review in Cell Metabolism Cell Metab. 22, 58-59 (2015)
Repurposing an osteoporosis drug for β cell regeneration in diabetic patients.
2015 Scientific Article in Journal of the American Heart Association J. Am. Heart Assoc. 4:e002153 (2015)
Heart-specific knockout of the mitochondrial Thioredoxin reductase (Txnrd2) induces metabolic and contractile dysfunction in the aging myocardium.
2015 Scientific Article in Transgenic Research Transgenic Res. 24, 921-927 (2015)
Blastocyst genotyping for quality control of mouse mutant archives: An ethical and economical approach.
2015 Scientific Article in Nature Communications Nat. Commun. 6:7796 (2015)
Glucocorticoids limit acute lung inflammation in concert with inflammatory stimuli by induction of SphK1.
2015 Scientific Article in Methods in Molecular Biology Methods Mol. Biol. 1322, 187-198 (2015)
Determination and analysis of cellular metabolic changes by noncanonical Hedgehog signaling.
2015 Scientific Article in Proceedings of the National Academy of Sciences of the United States of America Proc. Natl. Acad. Sci. U.S.A. 112, E3977-E3986 (2015)
Differential sensing for the regio- and stereoselective identification and quantitation of glycerides.
2015 Meeting abstract in Glia Glia 63, E64 (2015)
Identification and successful negotiation of a metabolic checkpoint in direct neuronal reprogramming.
2015 Scientific Article in Genome Research Genome Res. 25, 1295-1308 (2015)
Functional compensation among HMGN variants modulates the DNase I hypersensitive sites at enhancers.
2015 Scientific Article in American Journal of Clinical Nutrition Am. J. Clin. Nutr. 102, 345-352 (2015)
Dietary intake of soluble fiber and risk of islet autoimmunity by 5 y of age: Results from the TEDDY study.
2015 Review in Analytical and Bioanalytical Chemistry Anal. Bioanal. Chem. 407, 4879-4892 (2015)
Effects of pre-analytical processes on blood samples used in metabolomics studies.
2015 Scientific Article in Molecular and Cellular Endocrinology Mol. Cell. Endocrinol. 418, 42-54 (2015)
Emerging opportunities for the treatment of metabolic diseases: Glucagon-like peptide-1 based multi-agonists.
2015 Scientific Article in Brain, Behavior and Immunity Brain Behav. Immun. 50, 178-185 (2015)
Peripheral and central blockade of interleukin-6 trans-signaling differentially affects sleep architecture.
2015 Scientific Article in Atherosclerosis Atherosclerosis 241, 743-751 (2015)
Associations between calcium and vitamin D supplement use as well as their serum concentrations and subclinical cardiovascular disease phenotypes.
2015 Scientific Article in Diabetologia Diabetologia 58, 2317-2323 (2015)
Islet autoantibody phenotypes and incidence in children at increased risk for type 1 diabetes.
2015 Scientific Article in International Journal of Obesity Int. J. Obes. 39, 1733-1741 (2015)
Mesoderm Specific Transcript (MEST) is a negative regulator of human adipocyte differentiation.
2015 Scientific Article in Clinical Immunology Clin. Immunol. 160, 282–285 (2015)
Compromised immune response in infants at risk for type 1 diabetes born by Caesarean Section.
2015 Scientific Article in Journal of Clinical Investigation J. Clin. Invest. 125, 2736-2747 (2015)
S6K1 controls pancreatic β cell size independently of intrauterine growth restriction.
2015 Scientific Article in Cell Stem Cell Cell Stem Cell 17, 74-88 (2015)
Transcriptional mechanisms of proneural factors and REST in regulating neuronal reprogramming of astrocytes.
2015 Meeting abstract in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 10:P62 (2015)
Mind the Ga(b)p! – a novel hepatic gatekeeper at the switch point of metabolic homeostasis and diabetic late complications controlled by reactive metabolites.
2015 Meeting abstract in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 10:P311 (2015)
Hepatic heat shock proteins in diabetes and long term diabetic complications.
2015 Meeting abstract in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 10:FV12 (2015)
Transforming growth factor beta-like stimulated clone 22 D4 promotes diabetic hyperglycemia and insulin resistance.
2015 Scientific Article in Diabetologia Diabetologia 58, 2414-2423 (2015)
FGF21 is not required for glucose homeostasis, ketosis or tumour suppression associated with ketogenic diets in mice.
2015 Scientific Article in Steroids Steroids 103, 123-144 (2015)
Steroids in teleost fishes: A functional point of view.
2015 Scientific Article in SpringerPlus SpringerPlus 4:284 (2015)
Diabetes knowledge and glycemic control among patients with type 2 diabetes in Bangladesh.
2015 Review in Current Opinion in Endocrinology, Diabetes and Obesity Curr. Opin. Endocrinol. Diabetes Obes. 22, 270-276 (2015)
General population screening for type 1 diabetes: Has its time come?
2015 Scientific Article in PLoS Genetics PLoS Genet. 11:e1005274 (2015)
The human blood metabolome-transcriptome interface.
2015 Scientific Article in Diabetologia Diabetologia 58, 1845-1854 (2015)
Type 2 diabetes alters metabolic and transcriptional signatures of glucose and amino acid metabolism during exercise and recovery.
2015 Scientific Article in EMBO Molecular Medicine EMBO Mol. Med. 7, 1048-1062 (2015)
Transcriptional co-factor Transducin Beta-Like (TBL) 1 acts as a checkpoint in pancreatic cancer malignancy.
2015 Scientific Article in Development / Company of Biologists Development 142, 3239-3251 (2015)
Quantification of regenerative potential in primary human mammary epithelial cells.
2015 Scientific Article in Molecular and Cellular Proteomics Mol. Cell. Proteomics 14, 2764-2774 (2015)
The epoxyeicosatrienoic acid pathway enhances hepatic insulin signaling and is repressed in insulin-resistant mouse liver.
2015 Scientific Article in Nature Communications Nat. Commun. 6:7208 (2015)
Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels.
2015 Scientific Article in Gastroenterology Gastroenterology 149, 1042-1052 (2015)
T cells engineered to express a T-cell receptor specific for glypican-3 to recognize and kill hepatoma cells in vitro and in mice.
2015 Scientific Article in Developmental Cell Dev. Cell 33, 644-659 (2015)
MIM-induced membrane bending promotes dendritic spine initiation.
2015 Scientific Article in Frontiers in Endocrinology Front. Endocrin. 6:81 (2015)
Oxytocin reverses osteoporosis in a sex-dependent manner.
2015 Editorial in Bioanalysis Bioanalysis 7, 927-930 (2015)
Preanalytics: What can metabolomics learn from clinical chemistry?
2015 Scientific Article in Thorax Thorax 70, 862-872 (2015)
Microfibrillar-associated protein 4 modulates airway smooth muscle cell phenotype in experimental asthma.
2015 Scientific Article in Molecular Metabolism Mol. Metab. 4, 537-542 (2015)
Genetic disruption of uncoupling protein 1 in mice renders brown adipose tissue a significant source of FGF21 secretion.
2015 Scientific Article in Journal of Telemedicine and Telecare J. Telemed. Telecare 21, 400-407 (2015)
Internet health seeking behaviour of parents attending a general paediatric outpatient clinic: A cross-sectional observational study.
2015 Meeting abstract in Journal of Crohn's and Colitis J. Crohns Colitis 9, S177 (2015)
Outcomes of a large cohort of children with IBDU compared to other IBD subtypes and treatment options- a longitudinal report from the Porto pediatric IBD group of ESPGHAN.
2015 Meeting abstract in Journal of Crohn's and Colitis J. Crohns Colitis 9, S104 (2015)
Mitochondrial dysfunction impairs epithelial proliferative control and stemness in the intestinal crypts.
2015 Scientific Article in The American Journal of Gastroenterology : AJG Am. J. Gastroenterol. 110, 915-920 (2015)
HLA-DPB1*04:01 protects genetically susceptible children from celiac disease autoimmunity in the TEDDY study.
2015 Scientific Article in PLoS ONE PLoS ONE 10:e0128001 (2015)
Differences in the serum nonesterified fatty acid profile of young women associated with a recent history of gestational diabetes and overweight/obesity.
2015 Review in Journal of Comparative Physiology B J. Comp. Physiol. B 185, 587-606 (2015)
Brown adipose tissue: Physiological function and evolutionary significance.
2015 Scientific Article in Diabetes Diabetes 64, 3247-3252 (2015)
Reactivity to N-terminally truncated GAD65(96-585) identifies GAD autoantibodies that are more closely associated with diabetes progression in relatives of patients with type 1 diabetes.
2015 Scientific Article in Diabetes Care Diabetes Care 38, 989-996 (2015)
Predicting type 1 diabetes using biomarkers.
2015 Letter to the Editor in Diabetes Diabetes 64, e8-e9 (2015)
Response to comment on Heni et al. Central insulin administration improves whole-body insulin sensitivity via hypothalamus and parasympathetic outputs in men.
2015 Scientific Article in PLoS Biology PLoS Biol. 13:e1002151 (2015)
Applying the ARRIVE guidelines to an in vivo database.
2015 Scientific Article in PLoS ONE PLoS ONE 10:e0127368 (2015)
Associations of erythrocyte fatty acids in the de novo lipogenesis pathway with proxies of liver fat accumulation in the EPIC-Potsdam study.
2015 Scientific Article in Genetics Genetics 200, 707-718 (2015)
Non-additive effects of genes in human metabolomics.
2015 Scientific Article in Diabetes Diabetes 64, 3239-3246 (2015)
Detection of antibodies directed to the N-terminal region of GAD is dependent on assay format and contributes to differences in the specificity of GAD autoantibody assays for type 1 diabetes.
2015 Scientific Article in Diabetes Aktuell Diabetes akt. 13, 58-62 (2015)
5 Jahre erfolgreiche translationale Forschung - Deutsches Zentrum für Diabetesforschung.
2015 Scientific Article in Diabetes Aktuell Diabetes akt. 13, 83-86 (2015)
Unimolekulare Kombinationstherapie bei Diabetes und Adipositas - neue therapeutische Ansätze.
2015 Scientific Article in Diabetes Aktuell Diabetes akt. 13, 72-74 (2015)
Epigenetische Vererbung - ist die Zukunft diabetisch?
2015 Scientific Article in Nature Communications Nat. Commun. 6:7000 (2015)
Widespread seasonal gene expression reveals annual differences in human immunity and physiology.
2015 Scientific Article in PLoS ONE PLoS ONE 10:e0126804 (2015)
The brain response to peripheral insulin declines with age: A contribution of the blood-brain barrier?
2015 Review in Glia Glia 63, 1452-1468 (2015)
Reactive astrocytes as neural stem or progenitor cells: In vivo lineage, In vitro potential, and genome-wide expression analysis.
2015 Scientific Article in BMC Genomics BMC Genomics 16:351 (2015)
Genomic characterization of mutant laboratory mouse strains by exome sequencing and annotation lift-over.
2015 Scientific Article in Genome Research Genome Res. 25, 836-844 (2015)
Genomic redistribution of GR monomers and dimers mediates transcriptional response to exogenous glucocorticoid in vivo.
2015 Scientific Article in American Journal of Clinical Nutrition Am. J. Clin. Nutr. 101, 1241-1250 (2015)
Amino acids, lipid metabolites, and ferritin as potential mediators linking red meat consumption to type 2 diabetes.
2015 Scientific Article in Nucleic Acids Research Nucleic Acids Res. 41, W160-W168 (2015)
ProtPhylo: Identification of protein-phenotype and protein-protein functional associations via phylogenetic profiling.
2015 Scientific Article in PLoS ONE PLoS ONE 10:e0125304 (2015)
New mutation in the mouse Xpd/Ercc2 gene leads to recessive cataracts.
2015 Scientific Article in Cell Metabolism Cell Metab. 21, 678-691 (2015)
Hematopoietic Kit deficiency, rather than lack of mast cells, protects mice from obesity and insulin resistance.
2015 Scientific Article in Journal of Virology J. Virol. 89, 7248-7261 (2015)
K1 and K15 of Kaposi sarcoma-associated herpes virus are partial functional homologues of latent membrane protein 2A of Epstein-Barr virus.
2015 Scientific Article in Cellular Physiology and Biochemistry Cell. Physiol. Biochem. 35, 2272-2284 (2015)
Mice lacking Free Fatty Acid Receptor 1 (GPR40/FFAR1) are protected against conjugated linoleic acid-induced fatty liver but develop inflammation and insulin resistance in the brain.
2015 Meeting abstract in Journal of Investigative Dermatology, The J. Invest. Dermatol. 135, S111 (2015)
MSX1-induced neural crest-like reprograming promotes melanoma progression.
2015 Scientific Article in PLoS Genetics PLoS Genet. 11:e1005165 (2015)
The power of gene-based rare variant methods to detect disease-associated variation and test hypotheses about complex disease.
2015 Scientific Article in Molecular Metabolism Mol. Metab. 4, 519-527 (2015)
Fibroblast growth factor 21 is elevated in metabolically unhealthy obesity and affects lipid deposition, adipogenesis, and adipokine secretion of human abdominal subcutaneous adipocytes.
2015 Scientific Article in Journal of Psychiatric Research J. Psychiatr. Res. 65, 166-171 (2015)
Poor sleep quality is associated with impaired glucose tolerance in women after gestational diabetes.
2015 Scientific Article in Journal of Neuroscience J. Neurosci. 35, 6696-6702 (2015)
The role of sleep in motor sequence consolidation: Stabilization rather than enhancement.
2015 Meeting abstract in Experimental Dermatology Exp. Dermatol. 24, E15 (2015)
Psoriasis and cardiometabolic risk: independent association but distinct genetic architectures.
2015 Letter to the Editor in International Journal of Cardiovascular Imaging Int. J. Cardiovasc. Imaging 31, 1137 (2015)
Erratum to: High throughput phenotyping of left and right ventricular cardiomyopathy in calcineurin transgene mice.
2015 Meeting abstract in Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet. 123:P09_16 (2015)
Pilot study on the effects of cross-sex hormone treatment in transsexual persons on metabolism by means of metabolomics profiling.
2015 Scientific Article in Nature Reviews - Nephrology Nat. Rev. Nephrol. 11, 205-206 (2015)
New nonabsorbable potassium-exchange resins in hyperkalaemia.
2015 Scientific Article in JAMA: Journal of the American Medical Association JAMA 313, 1541-1549 (2015)
Effects of high-dose oral insulin on immune responses in children at high risk for type 1 diabetes: The Pre-POINT randomized clinical trial.
2015 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 100, E910-E918 (2015)
The diabetes risk phenotype of young women with recent gestational diabetes.
2015 Scientific Article in American Journal of Physiology - Lung Cellular and Molecular Physiology Am. J. Physiol. Lung Cell Mol. Physiol. 308, L1114-L1124 (2015)
Characterization of spontaneous air space enlargement in mice lacking microfibrillar-associated protein 4.
2015 Review in Molecular Metabolism Mol. Metab. 4, 437–460 (2015)
Ghrelin.
2015 Scientific Article in BMC Pediatrics BMC Pediatr. 15:24 (2015)
A method for reporting and classifying acute infectious diseases in a prospective study of young children: TEDDY.
2015 Scientific Article in Radiologe, Der Radiologe 55, 323-328 (2015)
Lebervolumen, Leberfettanteil und Körpergewicht im Verlauf einer Lebensstilinterventionsstudie : Eine Analyse mit quantitativen MR-basierten Methoden.
2015 Scientific Article in Cellular Physiology and Biochemistry Cell. Physiol. Biochem. 35, 1537-1545 (2015)
Activation of Extracellular signal-Regulated protein Kinases 1 and 2 (ERK1/2) by Free Fatty Acid Receptor 1 (FFAR1/GPR40) protects from palmitate-induced beta cell death, but plays no role in insulin secretion.
2015 Review in Human Molecular Genetics Hum. Mol. Genet. 24, 3582-3594 (2015)
Contribution of common non-synonymous variants in PCSK1 to body mass index variation and risk of obesity: A systematic review and meta-analysis with evidence from up to 331 175 individuals.
2015 Scientific Article in Metabolism: clinical and experimental Metabolism 64, 862-871 (2015)
Characterization of metabolically unhealthy normal-weight individuals: Risk factors and their associations with type 2 diabetes.
2015 Scientific Article in Pediatrics Pediatrics 135, 239-245 (2015)
Age at gluten introduction and risk of celiac disease.
2015 Scientific Article in Pediatrics Pediatrics 135, 627-634 (2015)
Clinical features of celiac disease: A prospective birth cohort.
2015 Scientific Article in Diabetologia Diabetologia 58, 980-987 (2015)
The 6 year incidence of diabetes-associated autoantibodies in genetically at-risk children: The TEDDY study.
2015 Scientific Article in Endocrinology Endocrinology 156, 1303-1315 (2015)
Brain innate immunity regulates hypothalamic arcuate neuronal activity and feeding behavior.
2015 Letter to the Editor in Molecular Metabolism Mol. Metab. 4, 365-366 (2015)
Beyond association: A functional role for Tcf7l2 in β-cell development.
2015 Review in Nature Reviews - Endocrinology Nat. Rev. Endocrinol. 11, 339–351 (2015)
Hypothalamic innate immune reaction in obesity.
2015 Scientific Article in Methods in Molecular Biology Methods Mol. Biol. 1295, 55-64 (2015)
Methods for proteomics-based analysis of the human muscle secretome using an in vitro exercise model.
2015 Letter to the Editor in Molecular Metabolism Mol. Metab. 4, 363–364 (2015)
Setting the TRAP for central leptin targets.
2015 Scientific Article in Journal of Biological Chemistry, The J. Biol. Chem. 290, 6531-6545 (2015)
Aldo-Keto Reductase 1B15 (AKR1B15): A mitochondrial human aldo-keto reductase with activity toward steroids and 3-keto-acyl-CoA conjugates.
2015 Scientific Article in Diabetes Care Diabetes Care 38, 1044-1050 (2015)
Selective insulin resistance in homeostatic and cognitive control brain areas in overweight and obese adults.
2015 Scientific Article in Methods in Molecular Biology Methods Mol. Biol. 1296, 161-171 (2015)
Microarray analysis of small non-coding RNAs.
2015 Scientific Article in Molecular Metabolism Mol. Metab. 4, 359-362 (2015)
When pigs fly, UCP1 makes heat.
2015 Scientific Article in Clinical Immunology Clin. Immunol. 157, 216-225 (2015)
Vagaries of the ELISpot assay: Specific detection of antigen responsive cells requires purified CD8+ T cells and MHC class I expressing antigen presenting cell lines.
2015 Scientific Article in Current Protocols of Mouse Biology Curr. Protoc. Mouse Biol. 5, 65-84 (2015)
Glucose tolerance tests for systematic screening of glucose homeostasis in mice.
2015 Scientific Article in PLoS ONE PLoS ONE 10:e0118534 (2015)
Brown adipose tissue harbors a distinct sub-population of regulatory T cells.
2015 Scientific Article in Circulation Circulation 131, 1191-1201 (2015)
ADAMTS-7 inhibits re-endothelialization of injured arteries and promotes vascular remodeling via cleavage of thrombospondin-1.
2015 Scientific Article in PLoS ONE PLoS ONE 10:e0117774 (2015)
Inverse agonistic action of 3-iodothyronamine at the human trace amine-associated receptor 5.
2015 Editorial in BioSpektrum BioSpektrum 21, 20-21 (2015)
Vererbung von Merkmalen außerhalb der primären Sequenz der DNA.
2015 Scientific Article in Environmental Health Perspectives Environ. Health Perspect. 123, 597-605 (2015)
Air pollution and atherosclerosis: A cross-sectional analysis of four European cohort studies in the ESCAPE study.
2015 Scientific Article in PLoS Genetics PLoS Genet. 11:e1004876 (2015)
Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus.
2015 Scientific Article in PLoS ONE PLoS ONE 10:e0118534 (2015)
Brown adipose tissue harbors a distinct sub-population of regulatory T cells.
2015 Scientific Article in Methods in Molecular Biology Methods Mol. Biol. 1296, 161-171 (2015)
Microarray analysis of small non-coding RNAs.
2015 Scientific Article in Journal of Immunology J. Immunol. 194, 2531-2538 (2015)
High diversity in the TCR repertoire of GAD65 autoantigen-specific human CD4+ T cells.
2015 Scientific Article in Diabetologia Diabetologia 58, 282-289 (2015)
Erythrocyte membrane fatty acid fluidity and risk of type 2 diabetes in the EPIC-Potsdam study.
2015 Scientific Article in Neurobiology of Learning and Memory Neurobiol. Learn. Mem. 119, 102-107 (2015)
Emotional memory can be persistently weakened by suppressing cortisol during retrieval.
2015 Scientific Article in Obesity Reviews Obes. Rev. 16, 273-281 (2015)
Compromised white matter integrity in obesity.
2015 Scientific Article in Diabetes Care Diabetes Care 38, 808-813 (2015)
Predictors of progression from the appearance of islet autoantibodies to early childhood diabetes: The Environmental Determinants of Diabetes in the Young (TEDDY).
2015 Scientific Article in EMBO Molecular Medicine EMBO Mol. Med. 7, 288-298 (2015)
Dual melanocortin-4 receptor and GLP-1 receptor agonism amplifies metabolic benefits in diet-induced obese mice.
2015 Scientific Article in BioMetals Biometals 28, 293-306 (2015)
Screen for alterations of iron related parameters in N-ethyl-N-nitrosurea-treated mice identified mutant lines with increased plasma ferritin levels.
2015 Scientific Article in International Journal of Cardiovascular Imaging Int. J. Cardiovasc. Imaging 31, 669-679 (2015)
High throughput phenotyping of left and right ventricular cardiomyopathy in calcineurin transgene mice.
2015 Scientific Article in Diabetologia Diabetologia 58, 255-264 (2015)
Low-energy diets differing in fibre, red meat and coffee intake equally improve insulin sensitivity in type 2 diabetes: A randomised feasibility trial.
In: Dagogo-Jack, S.* [Eds.]: Leptin : Regulation and Clinical Applications. 2015. 267-279
Novel combinatorial therapies involving leptin: Opportunities for mechanistic advances and therapeutic translation in human diseases,
2015 Scientific Article in Frontiers in Nutrition Front. Nutr. 1:31 (2015)
The pentapeptide RM-131 promotes food intake and adiposity in wildtype mice but not in mice lacking the ghrelin receptor.
2015 Scientific Article in Journal of Investigative Dermatology, The J. Invest. Dermatol. 135, 1283-1293 (2015)
Psoriasis and cardiometabolic traits: Modest association but distinct genetic architectures.
2015 Scientific Article in Journal of Neuroendocrinology J. Neuroendocrinol. 27, 419-423 (2015)
Insulin action in the human brain: Evidence from neuroimaging studies.
2015 Scientific Article in Diabetes Diabetes 64, 1966-1975 (2015)
Effects of intranasal insulin on hepatic fat accumulation and energy metabolism in humans.
2015 Scientific Article in Cell Reports Cell Rep. 10, 131-139 (2015)
Stem-cell-like properties and epithelial plasticity arise as stable traits after transient Twist1 activation.
2015 Scientific Article in Circulation Circulation 131, 774-785 (2015)
Metabolite profiling and cardiovascular event risk: A prospective study of three population-based cohorts.
2015 Scientific Article in Brain, Behavior and Immunity Brain Behav. Immun. 47, 178-185 (2015)
Effects of an interleukin-1 receptor antagonist on human sleep, sleep-associated memory consolidation, and blood monocytes.
2015 Scientific Article in Brain, Behavior and Immunity Brain Behav. Immun. 47, 201-210 (2015)
Differential acute effects of sleep on spontaneous and stimulated production of tumor necrosis factor in men.
2015 Scientific Article in Human Molecular Genetics Hum. Mol. Genet. 24, 2247-2266 (2015)
MTO1 mediates tissue-specificity of OXPHOS defects via tRNA modification and translation optimization, which can be bypassed by dietary intervention.
2015 Scientific Article in Gastroenterology Gastroenterology 148, 626-638 (2015)
Impaired autophagy induces chronic atrophic pancreatitis in mice via sex- and nutrition-dependent processes.
2015 Scientific Article in Developmental Biology Dev. Biol. 399, 2-14 (2015)
Loss of Npn1 from motor neurons causes postnatal deficits independent from Sema3A signaling.
2015 Scientific Article in EMBO Journal, The EMBO J. 34, 344-360 (2015)
microRNA-379 couples glucocorticoid hormones to dysfunctional lipid homeostasis.
2015 Scientific Article in Diabetes Care Diabetes Care 38, 329-332 (2015)
Early childhood gut microbiomes show strong geographic differences among subjects at high risk for type 1 diabetes.
2015 Scientific Article in Diabetes Diabetes 64, 1818-1829 (2015)
Role of Type 1 diabetes associated SNPs on risk of autoantibody positivity in the TEDDY study.
2015 Scientific Article in Diabetologia Diabetologia 58, 604-614 (2015)
GLP-1–oestrogen attenuates hyperphagia and protects from beta cell failure in diabetes-prone New Zealand Obese (NZO) mice.
2015 Editorial in Molecular Metabolism Mol. Metab. 4, 1-2 (2015)
The good, the bad, and the unknown: Fructose and FGF21.
2015 Scientific Article in Journal of natural medicines J. Nat. Med. 21, 27-36 (2015)
A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents.
2015 Scientific Article in Nucleic Acids Research Nucleic Acids Res. 53, D1171-D1175 (2015)
INFRAFRONTIER - providing mutant mouse resources as research tools for the international scientific community.
2015 Scientific Article in Journal of Nutritional Biochemistry, The J. Nutr. Biochem. 26, 75-81 (2015)
The development of diet-induced obesity and associated metabolic impairments in Dj-1 deficient mice.
2015 Scientific Article in Analytical and Bioanalytical Chemistry Anal. Bioanal. Chem. 407, 343-354 (2015)
Combining metabolomic non-targeted GC×GC-ToF-MS analysis and chemometric ASCA-based study of variances to assess dietary influence on type 2 diabetes development in a mouse model.
2015 Scientific Article in Endocrine Connections Endocr. Connect. 4, 1-8 (2015)
Functional characterization of a CDKN1B mutation in a Sardinian kindred with Multiple Endocrine Neoplasia type 4 (MEN4).
2015 Scientific Article in Diabetologia Diabetologia 58, 411-413 (2015)
Progression from single to multiple islet autoantibodies often occurs soon after seroconversion: Implications for early screening.
2015 Scientific Article in Molecular Metabolism Mol. Metab. 4, 39-50 (2015)
High fat diet-induced modifications in membrane lipid and mitochondrial-membrane protein signatures precede the development of hepatic insulin resistance in mice.
2015 Scientific Article in Journal of Leukocyte Biology J. Leukoc. Biol. 97, 111-120 (2015)
CD8+ CD122+ PD-1- effector cells promote the development of diabetes in NOD mice.
2015 Scientific Article in International Journal of Obesity Int. J. Obes. 39, 791-797 (2015)
Thermoneutral housing is a critical factor for immune function and diet-induced obesity in C57BL/6 nude mice.
2015 Scientific Article in Diabetologia Diabetologia 58, 374-383 (2015)
Nutritional strategy to prevent fatty liver and insulin resistance independent from obesity by reducing glucose-dependent insulinotropic polypeptide responses in mice.
2015 Scientific Article in Mammalian Genome Mamm. Genome 26, 33-42 (2015)
Generation of mice lacking DUF1220 protein domains: Effects on fecundity and hyperactivity.
2015 Scientific Article in Archivum Immunologiae et Therapiae Experimentalis Arch. Immunol. Ther. Exp. 63, 53-63 (2015)
Cyclosporine A regulates pro-inflammatory cytokine production in ulcerative colitis.
2015 Scientific Article in Diabetes Diabetes 64, 760-765 (2015)
Central nervous insulin administration does not potentiate the acute glucoregulatory impact of concurrent mild hyperinsulinemia.
2015 Scientific Article in Diabetes Diabetes 64, 284-290 (2015)
Metformin supports the antidiabetic effect of a sodium glucose cotransporter 2 inhibitor by suppressing endogenous glucose production in diabetic mice.
2015 Scientific Article in Acta Diabetologica Acta Diabetol. 52, 103-112 (2015)
Plasma copeptin is associated with type 2 diabetes in men but not in women in the population-based KORA F4 study.
2015 Scientific Article in Acta Diabetologica Acta Diabetol. 52, 621-624 (2015)
Early infant feeding and risk of developing islet autoimmunity and type 1 diabetes.
2015 Scientific Article in Neuropsychopharmacology Neuropsychopharmacology 40, 338-349 (2015)
Differential and converging molecular mechanisms of antidepressants' action in the hippocampal dentate gyrus.
2015 Scientific Article in International Journal of Obesity Int. J. Obes. 39, 353-360 (2015)
Attentional impulsivity in binge eating disorder modulates response inhibition performance and frontal brain networks.
2015 Scientific Article in Lancet Diabetes and Endocrinology Lancet Diabet. Endocrinol. 3, 52-62 (2015)
The metabolic burden of sleep loss.
2015 Scientific Article in Public Health Nutrition Public Health Nutr. 18, 50-58 (2015)