All HDC Publications
2022 Editorial in Diabetes, Stoffwechsel und Herz Diabetes Stoffwechs. Herz 31, 345-350 (2022)
Fatty Liver and Diabetes.
2022 Nature Cardiovascular Research Nat. Cardio. Res. 1, 529-531 (2022)
Publisher Correction: Extensive identification of genes involved in congenital and structural heart disorders and cardiomyopathy (Nature Cardiovascular Research, (2022), 1, 2, (157-173), 10.1038/s44161-022-00018-8).
2022 Kardiologie Kardiologie 16, 358-371 (2022)
Positionspapier Herzinsuffizienz und Diabetes.
2022 Editorial in Metabolism and Target Organ Damage Metab. Target. Organ. Damage 2:21 (2022)
Screening for advanced liver fibrosis in overweight and obese patients with NAFLD.
2022 Letter to the Editor in Diabetologie, Die Diabetologie 18, 426-430 (2022)
Diabetes and fatty liver.
2022 Letter to the Editor in Clinical and Translational Discovery Clin. Transl. Discovery 2:e153 (2022)
Breathe and burn: Novel roles for myoglobin in thermogenesis.
In: Comprehensive Pharmacology. 2022. 326-368 ( ; 2)
Gene Therapy.
2022 Review in Diabetologie, Die Diabetologie 18, 412-417 (2022)
Lipid therapy in patients with diabetes mellitus: A joint statement by the Commission on Lipid Metabolism and the working group Heart and Diabetes of the German Diabetes Society (DDG), the Section Diabetes, Obesity and Diabetology and Metabolism of the German Society of Endocrinology (DGE), the working group Heart and Diabetes of the German Society of Cardiology (DGK) and the joint working group Heart–Hormones–Diabetes of DGK, DGE and DDG.
2022 Scientific Article in American Journal of Clinical Nutrition Am. J. Clin. Nutr. 116, 394-403 (2022)
Sources of dietary gluten in the first 2 years of life and associations with celiac disease autoimmunity and celiac disease in Swedish genetically predisposed children: The Environmental Determinants of Diabetes in the Young (TEDDY) study.
2022 Scientific Article in Trials Trials 23:414 (2022)
INNODIA Master Protocol for the evaluation of investigational medicinal products in children, adolescents and adults with newly diagnosed type 1 diabetes.
2022 Scientific Article in Deutsches Ärzteblatt international Dtsch. Arztebl. Int. 119, 765-770 (2022)
SARS-CoV-2 seroprevalence in preschool and school-age children.
2022 Scientific Article in Bioinformatics Advances Bioinfo. Adv. 2:vbac042 (2022)
Correlation-guided Network Integration (CoNI), an R package for integrating numerical omics data that allows multiform graph representations to study molecular interaction networks.
2022 Scientific Article in Metabolites Metabolites 13:15 (2022)
Exercise-induced N-lactoylphenylalanine predicts adipose tissue loss during endurance training in overweight and obese humans.
2022 Scientific Article in Proceedings of the National Academy of Sciences of the United States of America Proc. Natl. Acad. Sci. U.S.A. 119:e2204527119 (2022)
Insulin regulates neurovascular coupling through astrocytes.
In: Molecular Exercise Physiology. 2022. 25 S. ( ; 11)
Altitude, temperature, circadian rhythms and exercise.
2022 Editorial in DDG-Informationen : Mitteilungen der Deutschen Diabetes-Gesellschaft DDG Informationen, 42-47 (2022)
Adipositas in Deutschland aus Sicht der DDG und der DAG.
2022 Editorial in DDG-Informationen : Mitteilungen der Deutschen Diabetes-Gesellschaft DDG Informationen, 241-247 (2022)
Das Deutsche Zentrum für Diabetesforschung – Aktuelles aus der Wissenschaft.
2022 Editorial in DDG-Informationen : Mitteilungen der Deutschen Diabetes-Gesellschaft DDG Informationen, 268-274 (2022)
Diabetes mellitus in Deutschland – politische Handlungsfelder 2021/22.
2022Vortrag: FEBS advanced practical course on fluorescence microscopy- Functional imaging of cellular dynamics, 17 June 2022, Amsterdam. (2022)
Inceptor: A novel inhibitor of insulin signaling.
2022 Scientific Article in Mammalian Genome Mamm. Genome 34, 229-243 (2022)
Knockout of the Complex III subunit Uqcrh causes bioenergetic impairment and cardiac contractile dysfunction.
2022 Scientific Article in Brain Sciences Brain Sci. 12:1648 (2022)
Availability of central α4β2* nicotinic acetylcholine receptors in human obesity.
2022 Scientific Article in Biomedicines Biomedicines 10:3151 (2022)
Associations of betatrophin/ANGPTL8 with septic dyslipidemia in human peritonitis: An explorative analysis.
2022 Scientific Article in Journal of Nephrology J. Nephrol. 36, 1461-1467 (2022)
Two cases of severe vitamin D3 intoxication treated with therapeutic plasma exchange and high cut-off hemodialysis.
2022 Scientific Article in Nutrients Nutrients 14:5220 (2022)
Maternal weight gain during pregnancy and the developing autonomic nervous system—possible impact of GDM.
2022 Scientific Article in BMC Neuroscience BMC Neurosci. 23:81 (2022)
Objective hearing threshold identification from auditory brainstem response measurements using supervised and self-supervised approaches.
2022 Scientific Article in Nature metabolism Nat. Metab. 4, 1697-1712 (2022)
Aberrant expression of agouti signaling protein (ASIP) as a cause of monogenic severe childhood obesity.
In: Physiological Consequences of Brain Insulin Action. 2022. 177-193
Brain insulin action in the control of metabolism in humans.
2022 Scientific Article in Frontiers in Nutrition Front. Nutr. 9:992682 (2022)
Intake of slow-digesting carbohydrates is related to changes in the microbiome and its functional pathways in growing rats with obesity induced by diet.
2022 Review in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 17, 445-460 (2022)
Früherkennung und Prävention des Typ-1-Diabetes.
2022 Scientific Article in Frontiers in Endocrinology Front. Endocrin. 13:1000650 (2022)
Associations of endogenous androgens and sex hormone-binding globulin with kidney function and chronic kidney disease.
2022 Review in Mammalian Genome Mamm. Genome 34, 331-350 (2022)
A rationale for considering heart/brain axis control in neuropsychiatric disease.
In: (2022 44th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), 11-15 July 2022, Glasgow, Scotland, United Kingdom). 2022. 541-544 ( ; 2022)
A Comparative Study on the Potential of Unsupervised Deep Learning-based Feature Selection in Radiomics.
2022Vortrag: European Islet Study Group Workshop 2022, June 13-15, 2022, Strasbourg, France. (2022)
Single-cell multiomics cross-species comparison of pancreas development.
2022Vortrag: 2022 Protein Processing, Trafficking and Secretion Gordon Research Conference, 07-17-2022, Colby-Sawyer College in New Hampshire, United States. (2022)
Inceptor is a (pro-)insulin degradation receptor.
2022 Scientific Article in BMC Women's Health BMC Womens Health 22:511 (2022)
Cancer prevention in females with and without obesity: Does perceived and internalised weight bias determine cancer prevention behaviour?
2022 Scientific Article in Clinical and translational medicine Clin. Transl. Med. 12:e1108 (2022)
Myoglobin-mediated lipid shuttling increases adrenergic activation of brown and white adipocyte metabolism and is as a marker of thermogenic adipocytes in humans.
2022 Scientific Article in Diabetologie, Die Diabetologie 19, 215-222 (2022)
Prädiabetes – eine Krankheit?
2022 Review in Diabetologie, Die Diabetologie 19, 136-143 (2022)
Do-it-yourself-Therapie für Menschen mit Typ-1-Diabetes. Ein „Citizen Science project“ zur Nutzung selbstentwickelter Technologien zur automatisierten Insulinabgabe.
2022 Scientific Article in eLife eLife 11:e82031 (2022)
T cells modulate the microglial response to brain ischemia.
2022 Review in Journal of Clinical Medicine J. Clin. Med. 11:7203 (2022)
Risk of contrast-associated acute kidney injury in patients undergoing peripheral angiography with carbon dioxide compared to iodine-containing contrast agents: A systematic review and meta-analysis.
2022 Scientific Article in Diabetes Diabetes 71, 2632-2641 (2022)
Islet autoantibody levels differentiate progression trajectories in individuals with presymptomatic type 1 diabetes.
2022 Scientific Article in BMC Endocrine Disorders BMC Endocr. Disord. 22:19 (2022)
Is staff consistency important to parents' satisfaction in a longitudinal study of children at risk for type 1 diabetes: The TEDDY study.
2022 Scientific Article in Leukemia Leukemia 37, 288-297 (2022)
A key role of the WEE1-CDK1 axis in mediating TKI-therapy resistance in FLT3-ITD positive acute myeloid leukemia patients.
2022 Scientific Article in Diabetologia Diabetologia 66, 579-589 (2022)
Serum neurofilament light chain: A novel biomarker for early diabetic sensorimotor polyneuropathy.
2022 Scientific Article in Turkish Journal of Nephrology Turk. J. Nephrol. 31, 391-392 (2022)
Widespread calcifications delineating an arterial vessel tree in a peritoneal dialysis patient.
2022 Scientific Article in HRB Open Research HRB Open Res. 4:42 (2022)
The effect of exercise interventions on inflammatory markers in major depressive disorder: Protocol for a systematic review and meta-analysis.
2022 Scientific Article in Nature metabolism Nat. Metab. 4, 1684–1696 (2022)
Mitochondrial RNA stimulates beige adipocyte development in young mice.
2022 Scientific Article in Cancers Cancers 14:5481 (2022)
Combined targeting of pathogenetic mechanisms in pancreatic neuroendocrine tumors elicits synergistic antitumor effects.
2022 Scientific Article in Journal of Clinical Medicine J. Clin. Med. 11:6762 (2022)
Diabetes and the prostate: Elevated fasting glucose, insulin resistance and higher levels of adrenal steroids in prostate cancer.
2022 Scientific Article in Magnetic Resonance in Medicine Magn. Reson. Med., DOI: 10.1002/mrm.29543 (2022)
Soy lecithin: A beneficial substance for adjusting the ADC in aqueous solutions to the values of biological tissues.
2022 Scientific Article in Scientific Reports Sci. Rep. 12:20791 (2022)
Analysis of genome-wide knockout mouse database identifies candidate ciliopathy genes.
2022 Scientific Article in Frontiers in Endocrinology Front. Endocrin. 13:1000094 (2022)
Is subcutaneous adipose tissue expansion in people living with lipedema healthier and reflected by circulating parameters?
2022 Scientific Article in Nature metabolism Nat. Metab. 4, 1591-1610 (2022)
Single-cell profiling of vascular endothelial cells reveals progressive organ-specific vulnerabilities during obesity.
2022 Scientific Article in Adipocyte Adipocyte 11, 630-642 (2022)
Associations of GHR, IGF-1 and IGFBP-3 expression in adipose tissue cells with obesity-related alterations in corresponding circulating levels and adipose tissue function in children.
2022 Scientific Article in Deutsches Ärzteblatt international Dtsch. Arztebl. Int. 119, 651-657 (2022)
Deutscher Diabetes-Risiko-Test zur Bestimmung des individuellen Typ-2-Diabetes-Risikos: 10-Jahres-Vorhersage und externe Validierungen.
2022 Scientific Article in Cell Reports Cell Rep. 41:111698 (2022)
Acute changes in systemic glycemia gate access and action of GLP-1R agonist on brain structures controlling energy homeostasis.
2022 Scientific Article in Frontiers in cell and developmental biology Front. Cell Dev. Biol. 10:965382 (2022)
Age-dependent increase of cytoskeletal components in sensory axons in human skin.
2022 Scientific Article in Nature Nature 612, 123-131 (2022)
Medin co-aggregates with vascular amyloid-β in Alzheimer’s disease.
2022 Scientific Article in Brain Sciences Brain Sci. 12:1437 (2022)
Central serotonin/noradrenaline transporter availability and treatment success in patients with obesity.
2022 Scientific Article in Molecular Metabolism Mol. Metab. 66:101626 (2022)
NIK/MAP3K14 in hepatocytes orchestrates NASH to hepatocellular carcinoma progression via JAK2/STAT5 inhibition.
2022 Letter to the Editor in Signal transduction and targeted therapy Signal Transduct. Target. Ther. 7:375 (2022)
Fire up the pyre: Inosine thermogenic signaling for obesity therapy.
2022 Scientific Article in Arteriosclerosis, Thrombosis, and Vascular Biology Arterioscler. Thromb. Vasc. Biol. 43, e29-e45 (2022)
Cargo-specific role for retriever subunit VPS26C in hepatocyte lipoprotein receptor recycling to control postprandial triglyceride-rich lipoproteins.
2022 Scientific Article in Nature Communications Nat. Commun. 13:6547 (2022)
Analytical and computational workflow for in-depth analysis of oxidized complex lipids in blood plasma.
2022 Scientific Article in Frontiers in Endocrinology Front. Endocrin. 13:891442 (2022)
Advanced glycation end-products are associated with diabetic neuropathy in young adults with type 1 diabetes.
2022 Scientific Article in Nature Communications Nat. Commun. 13:6754 (2022)
Altered glycolysis triggers impaired mitochondrial metabolism and mTORC1 activation in diabetic β-cells.
2022 Scientific Article in Pediatric Diabetes Pediatr. Diabetes 23, 1707-1716 (2022)
The emotional well-being of parents with children at genetic risk for type 1 diabetes before and during participation in the POInT-study.
2022 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 108, 865-875 (2022)
The acute cytokine response to 30 min exercise bouts before and after 8-week endurance training in subjects with obesity.
2022 Letter to the Editor in Lancet, The Lancet 400, 1826-1828 (2022)
Gut-hormone triple agonists: Clinical safety and metabolic benefits.
2022 Scientific Article in Allergy Allergy 78, 1218-1233 (2022)
Dietary digestible carbohydrates are associated with higher prevalence of asthma in humans and with aggravated lung allergic inflammation in mice.
2022 Scientific Article in American Journal of Physiology - Regulatory, Integrative and Comparative Physiology Am. J. Physiol.-Regul. Integr. Comp. Physiol. 324, R109-R119 (2022)
Aqp5--/-- mice exhibit reduced maximal O2 consumption under cold exposure, normal pulmonary gas exchange, and impaired formation of brown adipose tissue.
2022 Scientific Article in Nucleic Acids Research Nucleic Acids Res. 51, D539-D545 (2022)
CORUM: The comprehensive resource of mammalian protein complexes-2022.
2022 Scientific Article in Geburtshilfe und Frauenheilkunde Geburtsh. u. Frauenheilk. 82, 1265-1273 (2022)
COVID-19 and perinatal stress experience - a study conducted as part of the COVGEN initiative.
2022 Scientific Article in Cell Death & Disease Cell Death Dis. 13:902 (2022)
IKCa channels control breast cancer metabolism including AMPK-driven autophagy.
2022 Scientific Article in Scientific Reports Sci. Rep. 12:19793 (2022)
New C3H KitN824K/WT cancer mouse model develops late-onset malignant mammary tumors with high penetrance.
2022 Scientific Article in Cells Cells 11:3046 (2022)
Visceral adipose tissue E2F1-miRNA206/210 pathway associates with type 2 diabetes in humans with extreme obesity.
2022 Scientific Article in Computational and Structural Biotechnology Journal Comp. Struc. Biotech. J. 20, 5622-5638 (2022)
Integrative analysis of macrophage ribo-Seq and RNA-Seq data define glucocorticoid receptor regulated inflammatory response genes into distinct regulatory classes.
2022 Review in Pediatric Diabetes Pediatr. Diabetes 23, 1175-1187 (2022)
ISPAD clinical practice consensus guidelines 2022: Stages of type 1 diabetes in children and adolescents.
2022 Scientific Article in Cardiovascular Drugs and Therapy Cardiovasc. Drugs Ther., DOI: 10.1007/s10557-022-07386-0 (2022)
Novel insights into the management of patients with very high cardiovascular risk eligible for PCSK9 inhibitor treatment: Baseline findings from the PERI-DYS study.
2022 Scientific Article in Molecular Metabolism Mol. Metab. 65:101589 (2022)
Combined genetic deletion of GDF15 and FGF21 has modest effects on body weight, hepatic steatosis and insulin resistance in high fat fed mice.
2022 Scientific Article in Clinical Transplantation Clin. Transplant.:e14810 (2022)
Living kidney donor evaluation is associated with early identification of life-changing diagnosis in potentially healthy donor candidates.
2022 Scientific Article in Scientific Reports Sci. Rep. 12:15831 (2022)
Effects of adrenergic-stimulated lipolysis and cytokine production on in vitro mouse adipose tissue-islet interactions.
2022 Scientific Article in European Journal of Endocrinology Eur. J. Endocrinol. 187, 555-565 (2022)
Low IGF1 and high IGFBP1 predict diabetes onset in prediabetic patients.
2022 Scientific Article in Journal of Pharmaceutical and Biomedical Analysis : JPBA J. Pharm. Biomed. Anal. 221:115038 (2022)
Development and validation of an LC-MS/MS methodology for the quantification of thyroid hormones in dko MCT8/OATP1C1 mouse brain.
2022 Review in Cancer and Metastasis Reviews Cancer Metastasis Rev. 41, 517–547 (2022)
Obesity and cancer-extracellular matrix, angiogenesis, and adrenergic signaling as unusual suspects linking the two diseases.
2022 Editorial in Frontiers in Pharmacology Front. Pharmacol. 13:975812 (2022)
Editorial: Ion channels and transporters in diabetes and metabolic diseases.
2022 Scientific Article in Pediatric Diabetes Pediatr. Diabetes 23, 1586-1593 (2022)
HbA1c as a time predictive biomarker for an additional islet autoantibody and type 1 diabetes in seroconverted TEDDY children.
2022 Scientific Article in Brain stimulation Brain Stimul. 15, 1279-1289 (2022)
Vagus nerve stimulation increases stomach-brain coupling via a vagal afferent pathway.
2022 Scientific Article in Clinical Epigenetics Clin. Epigenet. 14:108 (2022)
OXTR DNA methylation differentiates men on the obesity spectrum with and without binge eating disorder.
2022 Scientific Article in Nature Communications Nat. Commun. 13:6830 (2022)
Deep phenotyping and lifetime trajectories reveal limited effects of longevity regulators on the aging process in C57BL/6J mice.
2022 Scientific Article in Human Molecular Genetics Hum. Mol. Genet. 32, 1266-1275 (2022)
Identifying causal serum protein-cardiometabolic trait relationships using whole genome sequencing.
2022 Nature Reviews - Endocrinology Nat. Rev. Endocrinol. 19:62 (2022)
Author Correction: Endosomal trafficking in metabolic homeostasis and diseases (Nature Reviews Endocrinology, (2022), 10.1038/s41574-022-00737-9).
2022 Scientific Article in Diabetes Care Diabetes Care 45, 2991–2998 (2022)
Finerenone in patients with chronic kidney disease and type 2 diabetes by sodium-glucose cotransporter 2 inhibitor treatment: The FIDELITY analysis.
2022 Scientific Article in Nature Communications Nat. Commun. 13:5062 (2022)
Reversal of the renal hyperglycemic memory in diabetic kidney disease by targeting sustained tubular p21 expression.
2022 Scientific Article in European Journal of Vascular and Endovascular Surgery Eur. J. Vasc. Endovasc. Surg. 64, 516-525 (2022)
Safety and efficacy of all-comers treated with paclitaxel-coated balloon for below the knee intervention.
2022 Review in Antioxidants Antioxidants 11:1541 (2022)
The prognostic value of derivatives-reactive oxygen metabolites (d-ROMs) for cardiovascular disease events and mortality: A review.
2022 Scientific Article in Circulation Research Circ. Res. 131:101161CIRCRESAHA122321295 (2022)
Retinol and retinol binding protein 4 levels and cardiometabolic disease risk.
2022 Scientific Article in Metabolites Metabolites 12:732 (2022)
A novel and cross-species active mammalian INDY (NaCT) inhibitor ameliorates hepatic steatosis in mice with diet-induced obesity.
2022 Scientific Article in Neurological Research and Practice Neurol. Res. Pract. 4:36 (2022)
Regional computed tomography perfusion deficits in patients with hypoglycemia: Two case reports.
2022 Scientific Article in Updates in Surgery Updates Surg. 74, 2011-2017 (2022)
Thoracoscopic mesh implantation as a definitive treatment approach for peritoneal dialysis-associated hydrothorax.
2022 Scientific Article in Frontiers in Immunology Front. Immunol. 13:958952 (2022)
A novel monoclonal IgG1 antibody specific for Galactose-alpha-1,3-galactose questions alpha-Gal epitope expression by bacteria.
2022 Review in Neuroscience and Biobehavioral Reviews Neurosci. Biobehav. Rev. 141:104807 (2022)
The role of hypoleptinemia in the psychological and behavioral adaptation to starvation: Implications for anorexia nervosa.
2022 Scientific Article in Toxicology Letters Toxicol. Lett. 368, 33-46 (2022)
In vitro/in silico prediction of drug induced steatosis in relation to oral doses and blood concentrations by the Nile Red assay.
2022 Scientific Article in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 17, S98-S110 (2022)
Definition, Klassifikation, Diagnostik und Differenzialdiagnostik des Diabetes mellitus: Update 2022.
2022 Scientific Article in Proceedings of the National Academy of Sciences of the United States of America Proc. Natl. Acad. Sci. U.S.A. 119:e2203165119 (2022)
Two distinct ways to form long-term object recognition memory during sleep and wakefulness.
2022 Review in Advanced Drug Delivery Reviews Adv. Drug Deliv. Rev. 189:114481 (2022)
Type 1 diabetes and engineering enhanced islet transplantation.
2022 Scientific Article in American Journal of Medical Genetics, Part C: Seminars in Medical Genetics Am. J. Med. Genet. C 190, 279-288 (2022)
Systematic assessment of monogenic etiology in adult-onset kidney stone formers undergoing urological intervention–evidence for genetic pretest probability.
2022 Scientific Article in Antioxidants Antioxidants 11:1689 (2022)
Exercise improves redox homeostasis and mitochondrial function in white adipose tissue.
2022 Scientific Article in Molecular Metabolism Mol. Metab. 64:101556 (2022)
Tryptophan metabolism is a physiological integrator regulating circadian rhythms.
2022 Review in MMW - Fortschritte der Medizin MMW-Fortschr. Med. 164, 67-69 (2022)
Rolle der genetischen Prädisposition. Risiko für Typ-1-Diabetes auch bei Nachkommen erhöht?
2022 Scientific Article in JAMA: Journal of the American Medical Association JAMA 328, 1252-1255 (2022)
SARS-CoV-2 infections and presymptomatic type 1 diabetes autoimmunity in children and adolescents from Colorado, USA, and Bavaria, Germany.
2022 Review in Deutsche Medizinische Wochenschrift - DMW Dtsch. Med. Wochenschr. 147, 1476-1481 (2022)
Behandlungsstrategien bei diabetischer Nephropathie – Update 2022.
2022 Editorial in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 17, 357-358 (2022)
Hunger metabolism - from molecular basis to therapeutic use Werner Creutzfeldt prize 2022-a brief overview of the award winner Stephan Herzig.
2022 Scientific Article in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 17, S215-S225 (2022)
Gestational diabetes mellitus (GDM), diagnosis, therapy and aftercare.
2022 Scientific Article in BMJ Open Diabetes Research & Care BMJ Open Diab. Res. Care 10:e002909 (2022)
Comprehensive validation of fasting-based and oral glucose tolerance test-based indices of insulin secretion against gold standard measures.
2022 Editorial in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 17, 353-356 (2022)
Zentralnervöse Prozesse bei der Prävention von Typ-2-Diabetes – Ferdinand-Bertram-Preis 2022 – eine Kurzübersicht der Preisträgerin Stephanie Kullmann.
2022 Scientific Article in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 17, S323-S326 (2022)
Diabetes mellitus und Herz.
2022 Review in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 17, S316-S322 (2022)
Lipid therapy in patients with diabetes mellitus - a joint statement by the lipid metabolism commission and the heart and diabetes working group of the German diabetes society (DDG), the diabetes, obesity and metabolism section of the German society for endocrinology (DGE), the heart and diabetes working group of the Germans society for cardiology (DGK) and the joint AG Heart-Hormone-Diabetes of the DGK, DGE and DDG.
2022 Review in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 17, S311-S315 (2022)
Diabetes und Fettleber.
2022 Review in Diabetologie, Die Diabetologie 18, 792–801 (2022)
Neue Ansätze zur Regeneration der insulinproduzierenden β-Zelle.
2022 Scientific Article in Diabetes Care Diabetes Care 45, 2892–2899 (2022)
Diabetes and obesity in down syndrome across the lifespan: A retrospective cohort study using U.K. electronic health records.
2022 Scientific Article in Frontiers in Endocrinology Front. Endocrin. 13:935016 (2022)
Diagnostic performance of sex-specific modified metabolite patterns in urine for screening of prediabetes.
2022 Scientific Article in Scientific Reports Sci. Rep. 12:16396 (2022)
Insight into the pulmonary molecular toxicity of heated tobacco products using human bronchial and alveolar mucosa models at air-liquid interface.
2022 Scientific Article in Frontiers in Behavioral Neuroscience Front. Behav. Neurosci. 16:923713 (2022)
Effects of information load on schema and episodic memory formation.
2022 Editorial in Molecular Metabolism Mol. Metab. 63:101547 (2022)
10 years of molecular metabolism.
2022 Scientific Article in Frontiers in Endocrinology Front. Endocrin. 13:892677 (2022)
Postprandial dynamics of proglucagon cleavage products and their relation to metabolic health.
2022 Review in Biomedicines Biomedicines 10:2461 (2022)
The legacy of parental obesity: Mechanisms of non-genetic transmission and reversibility.
2022 Scientific Article in Cells Cells 11:3289 (2022)
Dendritic cells or macrophages? The microenvironment of human clear cell renal cell carcinoma imprints a mosaic myeloid subtype associated with patient survival.
2022 Scientific Article in Redox Biology Redox Biol. 54:102353 (2022)
Remission of obesity and insulin resistance is not sufficient to restore mitochondrial homeostasis in visceral adipose tissue.
2022 Scientific Article in Nature Nature 609, 361–368 (2022)
Apoptotic brown adipocytes enhance energy expenditure via extracellular inosine.
2022 Scientific Article in Nature metabolism Nat. Metab. 4, 1150-1165 (2022)
Independent phenotypic plasticity axes define distinct obesity sub-types.
2022 Scientific Article in Annals of Surgery Ann. Surg. 276, 814-821 (2022)
Gastric bypass resolves metabolic dysfunction-associated fatty liver disease (MAFLD) in low-BMI patients: A prospective cohort study.
2022 Scientific Article in Diabetes Diabetes 71, 1962-1978 (2022)
Heterogeneous development of β-cell populations In diabetes-resistant and -susceptible mice.
2022 Scientific Article in Journal of applied laboratory medicine J. Appl. Lab. Med. 7, 1388-1400 (2022)
The common H202D variant in GDF-15 does not affect its bioactivity but can significantly interfere with measurement of Its circulating levels.
2022 Scientific Article in Human Molecular Genetics Hum. Mol. Genet. 31, 4019-4033 (2022)
Comparative genomic analyses of multiple backcross mouse populations suggest SGCG as a novel potential obesity-modifier gene.
2022 Scientific Article in Lancet Diabetes and Endocrinology Lancet Diabet. Endocrinol. 10, 589-596 (2022)
Two-age islet-autoantibody screening for childhood type 1 diabetes: A prospective cohort study.
2022 Scientific Article in EBioMedicine EBioMedicine 82:104118 (2022)
A classification and regression tree analysis identifies subgroups of childhood type 1 diabetes.
2022 Scientific Article in Glia Glia 70, 2062-2078 (2022)
Diet triggers specific responses of hypothalamic astrocytes in time and region dependent manner.
2022 Scientific Article in Molecular Metabolism Mol. Metab. 66:101616 (2022)
Validation of Mct8/Oatp1c1 dKO mice as a model organism for the Allan-Herndon-Dudley Syndrome.
2022 Scientific Article in Brain and behavior Brain Behav. 12:e2685 (2022)
Central correlates of placebo effects in nausea differ between men and women.
2022 Scientific Article in BMC Medicine BMC Med. 20:351 (2022)
Pan-cancer analysis of pre-diagnostic blood metabolite concentrations in the European Prospective Investigation into Cancer and Nutrition.
2022 Scientific Article in Cell Metabolism Cell Metab. 34, 1824-1842.e9 (2022)
Vps37a regulates hepatic glucose production by controlling glucagon receptor localization to endosomes.
2022 Scientific Article in Science Advances Sci. Adv. 8:eabo5555 (2022)
TSC22D4 interacts with Akt1 to regulate glucose metabolism.
2022 Scientific Article in Nature metabolism Nat. Metab. 4, 1071-1083 (2022)
GLP-1-mediated delivery of tesaglitazar improves obesity and glucose metabolism in male mice.
2022 Scientific Article in Advanced science Adv. Sci. 9:e2104291 (2022)
Trip13 depletion in liver cancer induces a lipogenic response contributing to plin2-dependent mitotic cell death.
2022 Scientific Article in Journal of Clinical Investigation J. Clin. Invest. 132:e162123 (2022)
Elevations in blood glucose before and after the appearance of islet autoantibodies in children.
2022 Scientific Article in JACC: Cardiovascular Interventions JACC-Cardiovasc. Interv. 15, 2093-2102 (2022)
Low-dose vs high-dose paclitaxel-coated balloons for femoropopliteal lesions: 2-Year results from the COMPARE Trial.
2022 Scientific Article in Diabetologia Diabetologia 66, 93-104 (2022)
Quantifying the utility of islet autoantibody levels in the prediction of type 1 diabetes in children.
2022 Scientific Article in Diabetologia Diabetologia 65, 93-104 (2022)
Progression likelihood score identifies substages of presymptomatic type 1 diabetes in childhood public health screening.
2022 Diabetologia Diabetologia, DOI: 10.1007/s00125-022-05798-z (2022)
Correction to: Progression likelihood score identifies substages of presymptomatic type 1 diabetes in childhood public health screening.
2022 Scientific Article in Obesity Obesity 30, 2233-2241 (2022)
Interscapular fat is associated with impaired glucose tolerance and insulin resistance independent of visceral fat mass.
2022 Scientific Article in Cell Metabolism Cell Metab. 34, 1532-1547.e6 (2022)
Hypothalamic astrocytes control systemic glucose metabolism and energy balance.
2022 Scientific Article in Genome Biology Genome Biol. 23:207 (2022)
H3K18 lactylation marks tissue-specific active enhancers.
2022 Scientific Article in Redox Biology Redox Biol. 57:102490 (2022)
Seizures, ataxia and parvalbumin-expressing interneurons respond to selenium supply in Selenop-deficient mice.
2022 Scientific Article in Metabolites Metabolites 12:846 (2022)
Fecal bile acids and neutral sterols are associated with latent microbial subgroups in the human gut.
2022 Scientific Article in Frontiers in Nutrition Front. Nutr. 9:933526 (2022)
Dynamic patterns of postprandial metabolic responses to three dietary challenges.
2022 Scientific Article in Cell Death Discovery Cell Death Discov. 8:387 (2022)
Mutations within the cGMP-binding domain of CNGA1 causing autosomal recessive retinitis pigmentosa in human and animal model.
2022 Scientific Article in BMC Medicine BMC Med. 20:327 (2022)
The effect of high-polyphenol Mediterranean diet on visceral adiposity: The DIRECT PLUS randomized controlled trial.
2022 Scientific Article in Circulation Circulation 146, 1189-1191 (2022)
Impaired myocardial mitochondrial respiration in humans with prediabetes: A footprint of prediabetic cardiomyopathy.
2022 Letter to the Editor in Journal of Hepatology J. Hepatol. 78, e129-e130 (2022)
Is NAFLD a key driver of brain dysfunction?
2022 Scientific Article in Proceedings of the National Academy of Sciences of the United States of America Proc. Natl. Acad. Sci. U.S.A. 119:e2110374119 (2022)
Leptin treatment has vasculo-protective effects in lipodystrophic mice.
2022 Review in Frontiers in cell and developmental biology Front. Cell Dev. Biol. 10:979251 (2022)
Reciprocal signaling between adipose tissue depots and the central nervous system.
2022 Scientific Article in Diabetes Care Diabetes Care 45, 2342-2349 (2022)
Rising hemoglobin A1c in the nondiabetic range predicts progression of type 1 diabetes as well as oral glucose tolerance tests.
2022 Scientific Article in Diabetes Care Diabetes Care 45, 2271-2281 (2022)
Predictors of the initiation of islet autoimmunity and progression to multiple autoantibodies and clinical diabetes: The TEDDY study.
2022 Review in Nature metabolism Nat. Metab. 4, 1097-1108 (2022)
Targeting pancreatic β cells for diabetes treatment.
2022 Editorial in Nature metabolism Nat. Metab. 4, 1093-1094 (2022)
Co-receptor regulation of insulin signaling.
2022 Scientific Article in EBioMedicine EBioMedicine 84:104276 (2022)
Machine learning for classification of hypertension subtypes using multi-omics: A multi-centre, retrospective, data-driven study.
2022 Scientific Article in Molecular Metabolism Mol. Metab. 66:101595 (2022)
A transcriptional cross species map of pancreatic islet cells.
2022 Other: Opinion in Nature Reviews - Endocrinology Nat. Rev. Endocrinol. 18, 523-524 (2022)
GLP1 receptor agonist overcomes SGLT2 inhibitor-related overeating.
2022 Scientific Article in JCI insight JCI insight 7:e161498 (2022)
Exercise restores brain insulin sensitivity in sedentary adults who are overweight and obese.
2022 Scientific Article in Nature metabolism Nat. Metab. 4, 883-900 (2022)
Food-seeking behavior is triggered by skin ultraviolet exposure in males.
2022 Scientific Article in Nature Communications Nat. Commun. 13:5447 (2022)
Dominant role of DNA methylation over H3K9me3 for IAP silencing in endoderm.
2022 Scientific Article in Obesity Surgery Obes. Surg. 32, 2495-2503 (2022)
Endoscopic bariatric treatment with duodenal-jejunal bypass liner improves Non-invasive markers of non-alcoholic steatohepatitis.
2022 Scientific Article in Scientific Reports Sci. Rep. 12:10325 (2022)
Adipose cells and tissues soften with lipid accumulation while in diabetes adipose tissue stiffens.
2022 Scientific Article in Metabolites Metabolites 12:548 (2022)
Intrinsic exercise capacity affects glycine and angiotensin-converting enzyme 2 (ACE2) levels in sedentary and exercise trained rats.
2022 Review in Advances in Experimental Medicine and Biology Adv. Exp. Med. Biol. 1390, 61-82 (2022)
Nuclear receptors in energy metabolism.
2022 Scientific Article in Biology Open Biol. Open 11:bio059403 (2022)
EPCAM and TROP2 share role in claudin stabilization and development of intestinal and extraintestinal epithelia in mice.
2022 Scientific Article in Life Science Alliance Life Sci. All. 5:e202201505 (2022)
Mitochondrial impairment and intracellular reactive oxygen species alter primary cilia morphology.
2022 Scientific Article in Molecular Metabolism Mol. Metab. 62:101518 (2022)
Proteasome dysfunction disrupts adipogenesis and induces inflammation via ATF3.
2022 Scientific Article in Journal of Lipid Research J. Lipid Res. 63:100238 (2022)
Inhibition of MAP4K4 signaling initiates metabolic reprogramming to protect hepatocytes from lipotoxic damage.
2022 Scientific Article in European Journal of Neurology Eur. J. Neurol. 29, 3081-3091 (2022)
Diabetic neuropathy is a generalized phenomenon with impact on hand functional performance and quality of life.
2022 Scientific Article in Current Medicinal Chemistry Curr. Med. Chem. 29, 6433-6445 (2022)
Proteolytic activity against the distal polybasic tract of the gamma subunit of the epithelial sodium channel ENaC in nephrotic urine.
2022 Scientific Article in The journal of experimental biology J. Exp. Biol. 225:jeb243860 (2022)
Obligatory homeothermy of mesic adapted African striped mice, Rhabdomys pumilio, is governed by seasonal basal metabolism and year-round "thermogenic readiness" of brown adipose tissue.
Methods in Molecular Biology In: Circadian Regulation. 2022. 311-327 (Methods Mol. Biol. ; 2482)
Untargeted and targeted circadian metabolomics using liquid chromatography-tandem mass spectrometry (LC-MS/MS) and flow injection-electrospray ionization-tandem mass spectrometry (FIA-ESI-MS/MS).
2022 Scientific Article in Diabetes Aktuell Diabetes akt. 20, 116-123 (2022)
Typ-1-Diabetes bei Kindern früh erkennen und präventiv handeln. Die Fr1da-Studie.
2022 Scientific Article in Methods in Molecular Biology Methods Mol. Biol. 2456, 123-140 (2022)
Phosphoproteomics and organelle proteomics in pancreatic islets.
2022 Scientific Article in International Journal of Molecular Sciences Int. J. Mol. Sci. 23:8558 (2022)
Metabolic effects of the waist-to-hip ratio associated locus GRB14/COBLL1 are related to GRB14 expression in adipose tissue.
2022 Scientific Article in Obesity Facts Obes. Facts 15, 685-693 (2022)
Suggestive evidence for an antidepressant effect of metreleptin treatment in patients with lipodystrophy.
2022 Editorial in Frontiers in Endocrinology Front. Endocrin. 13:999188 (2022)
Editorial: Adipose tissue dysfunction.
2022 Scientific Article in Diabetes, Obesity and Metabolism Diabetes Obes. Metab. 24, 1661-1666 (2022)
Eight weeks of empagliflozin does not affect pancreatic fat content and insulin secretion in people with prediabetes.
2022 Scientific Article in Computers in Biology and Medicine Comput. Biol. Med. 149:106049 (2022)
Computational exploration of the dual role of the phytochemical fortunellin: Antiviral activities against SARS-CoV-2 and immunomodulatory abilities against the host.
2022 Scientific Article in Nature Communications Nat. Commun. 13:4819 (2022)
Primary cilia and SHH signaling impairments in human and mouse models of Parkinson's disease.
2022 Scientific Article in Genetics in Medicine Genet. Med. 24, 2399-2407 (2022)
Biallelic loss-of-function variants in RABGAP1 cause a novel neurodevelopmental syndrome.
2022 Scientific Article in Life Sciences Life Sci. 303:120601 (2022)
Antibiotic-induced microbiome depletion remodels daily metabolic cycles in the brain.
2022 Scientific Article in Molecular Metabolism Mol. Metab. 61:101508 (2022)
PAT2 regulates vATPase assembly and lysosomal acidification in brown adipocytes.
2022 Scientific Article in Pediatric Diabetes Pediatr. Diabetes 23, 714-720 (2022)
Autoantibodies against ATP4A are a feature of the abundant autoimmunity that develops in first-degree relatives of patients with type 1 diabetes.
2022 Review in Acta Physiologica Acta Physiol. 235:e13844 (2022)
Rodent models to study sodium retention in experimental nephrotic syndrome.
2022 Scientific Article in Antioxidants Antioxidants 11:862 (2022)
Obesity hinders the protective effect of selenite supplementation on insulin signaling.
2022 Scientific Article in Nutrients Nutrients 14:1922 (2022)
L-serine supplementation blunts fasting-induced weight regain by increasing brown fat thermogenesis.
2022 Scientific Article in Scientific Reports Sci. Rep. 12:14608 (2022)
Monitoring longitudinal disease progression in a novel murine Kit tumor model using high-field MRI.
2022 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 107, 2329-2338 (2022)
Integration of infant metabolite, genetic and islet autoimmunity signatures to predict type 1 diabetes by 6 years of age.
2022 Review in Nature Reviews - Endocrinology Nat. Rev. Endocrinol. 18, 623-637 (2022)
The promise of new anti-obesity therapies arising from knowledge of genetic obesity traits.
2022 Scientific Article in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 17, 277-288 (2022)
Positionspapier Herzinsuffizienz und Diabetes.
2022 Scientific Article in Brain: A Journal of Neurology Brain 145, 4264-4274 (2022)
Gene therapy targeting the blood-brain barrier improves neurological symptoms in a model of genetic MCT8 deficiency.
2022 Scientific Article in Viruses Viruses 14:1591 (2022)
Influenza A virus infection reactivates human endogenous retroviruses associated with modulation of antiviral immunity.
2022 Scientific Article in Metabolites Metabolites 12:755 (2022)
Predicting hypertension subtypes with machine learning using targeted metabolites and their ratios.
2022 Scientific Article in Metabolites Metabolites 12:679 (2022)
Preanalytical pitfalls in untargeted plasma nuclear magnetic resonance metabolomics of endocrine hypertension.
2022 Scientific Article in Pharmaceutics Pharmaceutics 14:1527 (2022)
Thermosensitive PLGA-PEG-PLGA hydrogel as depot matrix for allergen-specific immunotherapy.
2022 Scientific Article in Nature Nature 608, 778-783 (2022)
A non-canonical vitamin K cycle is a potent ferroptosis suppressor.
2022 Scientific Article in PLoS ONE PLoS ONE 17:e0267258 (2022)
A novel smartphone app to change risk behaviors of women after gestational diabetes: A randomized controlled trial.
2022 Scientific Article in Biomedicines Biomedicines 10:825 (2022)
A novel anti-CD73 antibody that selectively inhibits membrane 2 CD73 shows antitumor activity and induces tumor immune escape.
2022 Scientific Article in American Journal of Clinical Nutrition Am. J. Clin. Nutr. 116, 165-172 (2022)
Changes in circulating MicroRNAs-99/100 and reductions of visceral and ectopic fat depots in response to lifestyle interventions: The CENTRAL trial.
2022 Scientific Article in Deutsches Ärzteblatt international Dtsch. Arztebl. Int. 119, 70-80 (2022)
Obesity surgery.
2022 Scientific Article in Endocrine-Related Cancer Endocr. Relat. Cancer 29, 285-306 (2022)
Personalized drug testing in human pheochromocytoma/paraganglioma primary cultures.
2022 Editorial in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 107, e3080-e3081 (2022)
Spotlight on the human brain - central actions of SGLT2 inhibitors?
2022 Scientific Article in Cells Cells 11:1341 (2022)
FK506-binding protein 11 is a novel plasma cell-specific antibody folding catalyst with increased expression in idiopathic pulmonary fibrosis.
2022 Scientific Article in Molecular Metabolism Mol. Metab. 60:101497 (2022)
Angiopoietin-like 4 governs diurnal lipoprotein lipase activity in brown adipose tissue.
2022 Scientific Article in BMC Microbiology BMC Microbiol. 22:91 (2022)
Pharmacologically induced weight loss is associated with distinct gut microbiome changes in obese rats.
2022 Scientific Article in Nature Communications Nat. Commun. 13:4540 (2022)
Synaptotagmin-13 orchestrates pancreatic endocrine cell egression and islet morphogenesis.
2022 Review in Frontiers in Endocrinology Front. Endocrin. 13:859044 (2022)
Immune cell regulation of white adipose progenitor cell fate.
2022 Scientific Article in Metabolites Metabolites 12:293 (2022)
Ramipril reduces acylcarnitines and distinctly increases angiotensinconverting enzyme 2 expression in lungs of rats.
2022 Scientific Article in European Journal of Nuclear Medicine and Molecular Imaging Eur. J. Nucl. Med. Mol. Imaging 49, 4338-4357 (2022)
X-ray multiscale 3D neuroimaging to quantify cellular aging and neurodegeneration postmortem in a model of Alzheimer’s disease.
2022 Scientific Article in Molecular Metabolism Mol. Metab. 60:101487 (2022)
Hepatocyte-specific activity of TSC22D4 triggers progressive NAFLD by impairing mitochondrial function.
2022 Scientific Article in EMBO Reports EMBO Rep.:e54078 (2022)
A novel stem cell type at the basal side of the subventricular zone maintains adult neurogenesis.
2022 Scientific Article in Non-coding RNA Non-coding RNA 8:32 (2022)
Comprehensive transcriptional profiling and mouse phenotyping reveals dispensable role for adipose tissue selective long noncoding RNA Gm15551.
2022 Scientific Article in BMC Cancer BMC Cancer 22:386 (2022)
Invadopodia play a role in prostate cancer progression.
2022 Scientific Article in International Journal of Obesity Int. J. Obes. 46, 1319-1327 (2022)
The effect of intranasal insulin on appetite and mood in women with and without obesity: An experimental medicine study.
2022 Scientific Article in Obesity Facts Obes. Facts 15, 281-291 (2022)
De-novo and depot-specific androgen production in human adipose tissue - a source of hyperandrogenism in women with obesity.
2022 Review in Diabetologie, Die Diabetologie 18, 758–768 (2022)
Molekulargenetische Diagnostik des Diabetes mellitus.
2022 Editorial in Deutsche Medizinische Wochenschrift - DMW Dtsch. Med. Wochenschr. 147, 377-378 (2022)
79-jährige Patientin mit nephrotischer Proteinurie.
2022 Review in Sleep Medicine Sleep Med. 92, 50-58 (2022)
The effect of slow-wave sleep and rapid eye-movement sleep interventions on glycaemic control: A systematic review and meta-analysis of randomised controlled trials.
2022 Scientific Article in Journal of Feline Medicine and Surgery Open Reports JFMS Open Rep. 8, 20551169221081398 (2022)
Recovery after inadvertent intramedullary microchip implantation at C1–C2 in a kitten.
2022 Scientific Article in International Journal of Molecular Sciences Int. J. Mol. Sci. 23:7418 (2022)
Biological role of the intercellular transfer of glycosylphosphatidylinositol-anchored proteins: Stimulation of lipid and glycogen synthesis.
2022 Editorial in Frontiers in Endocrinology Front. Endocrin. 13:933562 (2022)
Editorial: Covid-19 and diabetes.
2022 Scientific Article in FEBS Letters FEBS Lett. 596, 1434-1444 (2022)
Adipocyte-specific CDK7 ablation leads to progressive loss of adipose tissue and metabolic dysfunction.
2022 Scientific Article in Scientific Reports Sci. Rep. 12:4516 (2022)
Telomere length is not a main factor for the development of islet autoimmunity and type 1 diabetes in the TEDDY study.
2022 Review in Frontiers in Endocrinology Front. Endocrin. 13:838410 (2022)
Recent advances in incretin-based pharmacotherapies for the treatment of obesity and diabetes.
2022 Scientific Article in Pflügers Archiv Pflugers Arch. 474, 613-624 (2022)
Sodium retention in nephrotic syndrome is independent of the activation of the membrane-anchored serine protease prostasin (CAP1/PRSS8) and its enzymatic activity.
2022 Review in Endocrinology, Diabetes and Metabolism Endocrinol. Diabetes Metab. 5:e00330 (2022)
Managing weight and glycaemic targets in people with type 2 diabetes—How far have we come?
2022 Scientific Article in Scientific Reports Sci. Rep. 12:4795 (2022)
Shear stress switches the association of endothelial enhancers from ETV/ETS to KLF transcription factor binding sites.
2022 Scientific Article in Science Science 376:eabf9088 (2022)
Spatial centrosome proteome of human neural cells uncovers disease-relevant heterogeneity.
2022 Scientific Article in Nature Methods Nat. Methods 19, 803-811 (2022)
Mass spectrometry-based draft of the mouse proteome.
2022 Scientific Article in Diabetes Care Diabetes Care 45, 1911-1913 (2022)
Changes in circulating miR-375-3p and improvements in visceral and hepatic fat contents in response to lifestyle interventions: The CENTRAL trial.
2022 Scientific Article in Microbiome Microbiome 10:96 (2022)
Functional changes of the gastric bypass microbiota reactivate thermogenic adipose tissue and systemic glucose control via intestinal FXR-TGR5 crosstalk in diet-induced obesity.
2022 Scientific Article in Basic Research in Cardiology Basic Res. Cardiol. 117:32 (2022)
Reduction of A-to-I RNA editing in the failing human heart regulates formation of circular RNAs.
2022 Scientific Article in Cell Reports Cell Rep. 39:110910 (2022)
ATGL-dependent white adipose tissue lipolysis controls hepatocyte PPARα activity.
2022 Scientific Article in Clinical and translational medicine Clin. Transl. Med. 12:e851 (2022)
DNA methylation patterns reflect individual's lifestyle independent of obesity.
2022 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 107, 2167-2181 (2022)
Six-month periodic fasting in patients with type 2 diabetes and diabetic nephropathy: A proof-of-concept study.
2022 Scientific Article in Nature Communications Nat. Commun. 13:3151 (2022)
Temporal changes in gastrointestinal fungi and the risk of autoimmunity during early childhood: The TEDDY study.
2022 Scientific Article in Diabetes Diabetes 71, 1937-1945 (2022)
Fat-distribution patterns and future type-2 diabetes.
2022 Scientific Article in Diabetes Care Diabetes Care 45, 1822-1832 (2022)
Maternal dietary glycemic index and glycemic load in pregnancy and offspring cord blood DNA methylation.
2022 Review in Nutrients Nutrients 14:2084 (2022)
Nutrients and the circadian clock: A partnership controlling adipose tissue function and health.
2022 Scientific Article in Human Molecular Genetics Hum. Mol. Genet. 31, 3377–3391 (2022)
Multi-ancestry genome-wide association study of gestational diabetes mellitus highlights genetic links with type 2 diabetes.
2022 Scientific Article in Scientific Reports Sci. Rep. 12:3410 (2022)
Evaluation of parameters for fetal behavioural state classification.
2022 Scientific Article in Frontiers in Bioscience Front. Biosci. 27:56 (2022)
Pre-pregnancy BMI but not mild stress directly influences Interleukin-6 levels and insulin sensitivity during late pregnancy.
2022 Scientific Article in Frontiers in Nutrition Front. Nutr. 9:808346 (2022)
High protein diets improve liver fat and insulin sensitivity by prandial but not fasting glucagon secretion in type 2 diabetes.
2022 Scientific Article in Science Signaling Sci. Signal. 15:eabk3083 (2022)
Phosphorylation of serine-893 in CARD11 suppresses the formation and activity of the CARD11-BCL10-MALT1 complex in T and B cells.
2022 Scientific Article in Frontiers in Neuroscience Front. Neurosci. 15:811085 (2022)
Magnetic resonance neurography reveals smoking-associated decrease in sciatic nerve structural integrity in Type 2 diabetes.
2022 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 107, 1520-1528 (2022)
Childhood height growth rate association with the risk of islet autoimmunity and development of type 1 diabetes.
2022 Scientific Article in Environmental Research Environ. Res. 212:113503 (2022)
Association of long-term environmental exposures in pregnancy and early life with islet autoimmunity development in children in Bavaria, Germany.
2022 Scientific Article in Frontiers in Immunology Front. Immunol. 13:818984 (2022)
Construction of a lactate-related prognostic signature for predicting prognosis, tumor microenvironment, and immune response in kidney renal clear cell carcinoma.
2022 Letter to the Editor in Journal of Cell Science J. Cell Sci. 135:jcs259793 (2022)
First person - Syed Qaaifah Gillani.
2022 Scientific Article in International Journal of Obesity Int. J. Obes. 46, 1662–1670 (2022)
Sex differences in central insulin action: Effect of intranasal insulin on neural food cue reactivity in adults with normal weight and overweight.
2022 Review in FEBS Letters FEBS Lett. 596, 2596-2616 (2022)
How to tame your genes: Mechanisms of inflammatory gene repression by glucocorticoids.
2022 Scientific Article in Biochemical and Biophysical Research Communications Biochem. Biophys. Res. Commun. 618, 46-53 (2022)
TSC22D4 promotes TGFβ1-induced activation of hepatic stellate cells.
2022 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 107, e2417-e2424 (2022)
Impaired metabolic health and low cardiorespiratory fitness independently associate with subclinical atherosclerosis in obesity.
2022 Scientific Article in Nature Cardiovascular Research Nat. Cardio. Res. 1, 157-173 (2022)
Extensive identification of genes involved in congenital and structural heart disorders and cardiomyopathy.
2022 Scientific Article in International Journal of Molecular Sciences Int. J. Mol. Sci. 23:2222 (2022)
Adipsin serum concentrations and adipose tissue expression in people with obesity and type 2 diabetes.
2022 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 107, e2425-e2430 (2022)
Incretin hypersecretion in gestational diabetes mellitus.
2022 Scientific Article in Environment International Environ. Int. 164:107279 (2022)
Di-(2-ethylhexyl) phthalate substitutes accelerate human adipogenesis through PPARγ activation and cause oxidative stress and impaired metabolic homeostasis in mature adipocytes.
2022 Scientific Article in Metabolites Metabolites 12:99 (2022)
Analogues of natural chalcones as efficient inhibitors of AKR1C3.
2022 Scientific Article in Diagnostics Diagnostics 12:308 (2022)
An antibody-aptamer-hybrid lateral flow assay for detection of CXCL9 in antibody-mediated rejection after kidney transplantation.
2022 Scientific Article in Cells Cells 11:560 (2022)
Treatment of pheochromocytoma cells with recurrent cycles of hypoxia: A new pseudohypoxic in vitro model.
2022 Scientific Article in Endocrine-Related Cancer Endocr. Relat. Cancer 29, 121-128 (2022)
Spironolactone is associated with reduced mitotane levels in adrenocortical carcinoma patients.
2022 Review in Biomedicines Biomedicines 10:126 (2022)
Impact of physical activity and exercise on the epigenome in skeletal muscle and effects on systemic metabolism.
2022 Scientific Article in Metabolites Metabolites 12:445 (2022)
Effects of acute and chronic resistance exercise on the skeletal muscle metabolome.
2022 Scientific Article in Frontiers in Medicine Front. Med. 9:875430 (2022)
Obesity and impaired metabolic health increase risk of COVID-19-related mortality in young and middle-aged adults to the level observed in older people: The LEOSS Registry.
2022 Review in Trends in Endocrinology and Metabolism Trends Endocrinol. Metab. 33, 493-506 (2022)
Regulatory networks determining substrate utilization in brown adipocytes.
2022 Scientific Article in Genome Medicine Genome Med. 14:51 (2022)
Breast cancer risks associated with missense variants in breast cancer susceptibility genes.
2022 Scientific Article in Cell Reports Cell Rep. 39:110835 (2022)
Calorie restriction and calorie dilution have different impacts on body fat, metabolism, behavior, and hypothalamic gene expression.
2022 Scientific Article in Acta Diabetologica Acta Diabetol. 59, 687-696 (2022)
Intra-lymphatic administration of GAD-alum in type 1 diabetes: Long-term follow-up and effect of a late booster dose (the DIAGNODE Extension trial).
2022 Scientific Article in Journal of Magnetic Resonance Imaging J. Magn. Reson. Imaging 56:2102395 (2022)
Short-term variability of proton density fat fraction in pancreas and liver assessed by multiecho chemical-shift encoding-based MRI at 3 T.
2022 Scientific Article in Cell Reports Medicine Cell Rep. Med. 3:100477 (2022)
Four groups of type 2 diabetes contribute to the etiological and clinical heterogeneity in newly diagnosed individuals: An IMI DIRECT study.
2022 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 107, E1899-E1906 (2022)
Circulating levels of microRNA-122 and hepatic fat change in response to weight-loss interventions: CENTRAL Trial.
2022 Scientific Article in Journal of Neurophysiology J. Neurophysiol. 127, 548-558 (2022)
Intranasal orexin A modulates sympathetic vascular tone - a pilot study in healthy male humans.
2022 Scientific Article in Scientific Reports Sci. Rep. 12:504 (2022)
Endoplasmic reticulum stress and the unfolded protein response in skeletal muscle of subjects suffering from peritoneal sepsis.
2022 Scientific Article in Cell Death & Disease Cell Death Dis. 13:53 (2022)
Danger signal extracellular calcium initiates differentiation of monocytes into SPP1/osteopontin-producing macrophages.
2022 Review in Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet. 127, 2, S97-S101 (2022)
Position paper on lipid therapy in patients with diabetes mellitus.
2022 Review in Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet. 130, 1, S123-S126 (2022)
Diabetes mellitus and the heart.
2022 Scientific Article in Frontiers in Neuroscience Front. Neurosci. 15:741494 (2022)
Fractional anisotropy and troponin T parallel structural nerve damage at the upper extremities in a group of patients with prediabetes and type 2 diabetes - a study using 3T magnetic resonance neurography.
2022 Review in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 17, 382-388 (2022)
Auto-Antikörper-Diagnostik in der Diabetologie – Aktueller Stand der Analytik und klinische Anwendung in Deutschland.
2022 Scientific Article in Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet. 130, 1, S113-S116 (2022)
Diabetes and fatty Liver.
2022 Scientific Article in Cell Chemical Biology Cell Chem. Bio. 29, 680-689.e6 (2022)
An antisense transcript transcribed from Irs2 locus contributes to the pathogenesis of hepatic steatosis in insulin resistance.
2022 Scientific Article in iScience iScience 25:103680 (2022)
An adipose lncRAP2-Igf2bp2 complex enhances adipogenesis and energy expenditure by stabilizing target mRNAs.
2022 Scientific Article in Journal of Immunological Methods J. Immunol. Methods 502:113227 (2022)
Reproducibility of 10x Genomics single cell RNA sequencing method in the immune cell environment.
2022 Scientific Article in Molecular Metabolism Mol. Metab. 57:101436 (2022)
NFE2L1-mediated proteasome function protects from ferroptosis.
2022 Scientific Article in Communications Biology Comm. Biol. 5:408 (2022)
Dietary intervention improves health metrics and life expectancy of the genetically obese Titan mouse.
2022 Scientific Article in PLoS Genetics PLoS Genet. 18:e1010190 (2022)
Mice lacking the mitochondrial exonuclease MGME1 develop inflammatory kidney disease with glomerular dysfunction.
2022 Scientific Article in BMJ Open BMJ Open 12:e058268 (2022)
The German Gestational Diabetes Study (PREG), a prospective multicentre cohort study: Rationale, methodology and design.
2022 Review in Sports Medicine Sports Med. 52, 2569–2578 (2022)
Does a hypertrophying muscle fibre reprogramme its metabolism similar to a cancer cell?
2022 Scientific Article in Scientific Reports Sci. Rep. 12:2297 (2022)
Blood and adipose tissue steroid metabolomics and mRNA expression of steroidogenic enzymes in periparturient dairy cows differing in body condition.
2022 Scientific Article in Cells Cells 11:520 (2022)
Innate immune pathways promote oligodendrocyte progenitor cell recruitment to the injury site in adult Zebrafish brain.
2022 Scientific Article in Transgenic Research Transgenic Res. 31, 227-237 (2022)
Skeletal muscle phenotyping of Hippo gene-mutated mice reveals that Lats1 deletion increases the percentage of type I muscle fibers.
2022 Scientific Reports Sci. Rep. 12:6793 (2022)
Author Correction: Maternal whole blood cell miRNA-340 is elevated in gestational diabetes and inversely regulated by glucose and insulin (Scientific Reports, (2018), 8, 1, (1366), 10.1038/s41598-018-19200-9).
2022 Scientific Article in eLife eLife 11:e76090 (2022)
Active site geometry stabilization of a presenilin homolog by the lipid bilayer promotes intramembrane proteolysis.
2022 Scientific Article in Biomedicines Biomedicines 10:616 (2022)
Bezafibrate reduces elevated hepatic fumarate in insulin-deficient mice.
2022 Scientific Article in Research in veterinary science Res. Vet. Sci. 146, 60-69 (2022)
Epaxial muscle atrophy is more evident in large dogs with intervertebral disc disease than in dogs with ischaemic myelopathy.
2022 Scientific Article in Diabetologia Diabetologia 65, 1278-1290 (2022)
Insulin allergy: A diagnostic and therapeutic strategy based on a retrospective cohort and a case–control study.
2022 Other: News Item in Nature metabolism Nat. Metab., DOI: 10.1038/s42255-022-00563-3 (2022)
Astroglial clean-up of satiety synapses.
2022 Letter to the Editor in Med (N Y) Med. 3, 279-280 (2022)
Awaking sleeping islets for a cure of diabetes.
2022 Scientific Article in Diabetologia Diabetologia 65, 1212-1221 (2022)
Sleep deprivation prevents counterregulatory adaptation to recurrent hypoglycaemia.
2022 Scientific Article in Diabetes Diabetes 71, 1363-1370 (2022)
Circulating metabolites associate with and improve the prediction of all-cause mortality in type 2 diabetes.
2022 Review in Diabetes Diabetes 71, 610-623 (2022)
Screening for type 1 diabetes in the general population: A status report and perspective.
2022 Scientific Article in EMBO Molecular Medicine EMBO Mol. Med.:e14364 (2022)
Angpt2/Tie2 autostimulatory loop controls tumorigenesis.
2022 Scientific Article in EMBO Molecular Medicine EMBO Mol. Med.:e14797 (2022)
Parkinson's disease motor symptoms rescue by CRISPRa-reprogramming astrocytes into GABAergic neurons.
2022 Scientific Article in EMBO Molecular Medicine EMBO Mol. Med.:e14817 (2022)
Early disruption of photoreceptor cell architecture and loss of vision in a humanized pig model of usher syndromes.
2022 Scientific Article in Proceedings of the National Academy of Sciences of the United States of America Proc. Natl. Acad. Sci. U.S.A. 119:e2200083119 (2022)
Disruption of the circadian clock component BMAL1 elicits an endocrine adaption impacting on insulin sensitivity and liver disease.
2022 Scientific Article in Microbiome Microbiome 10:57 (2022)
Effects of caloric restriction on the gut microbiome are linked with immune senescence.
2022 Scientific Article in Nature Communications Nat. Commun. 13:1514 (2022)
Progression of type 1 diabetes from latency to symptomatic disease is predicted by distinct autoimmune trajectories.
2022 Scientific Article in Neuron Neuron 110, 1516-1531.e9 (2022)
Neuronal mitochondria transport Pink1 mRNA via synaptojanin 2 to support local mitophagy.
2022 Scientific Article in Basic Research in Cardiology Basic Res. Cardiol. 117:11 (2022)
Uncovering the molecular identity of cardiosphere-derived cells (CDCs) by single-cell RNA sequencing.
2022 Scientific Article in Diabetes Care Diabetes Care 45, 614-623 (2022)
Maternal glycemic dysregulation during pregnancy and neonatal blood DNA methylation: Meta-analyses of epigenome-wide association studies.
2022 Scientific Article in Nature Communications Nat. Commun. 13:1223 (2022)
Sirtuin-1 sensitive lysine-136 acetylation drives phase separation and pathological aggregation of TDP-43.
2022 Scientific Article in Cell Metabolism Cell Metab. 34, 473-486.e9 (2022)
A macrophage-hepatocyte glucocorticoid receptor axis coordinates fasting ketogenesis.
2022 Scientific Article in Cardiovascular Research Cardiovasc. Res., DOI: 10.1093/cvr/cvac022 (2022)
Properties and fate of human mesenchymal stem cells upon miRNA let-7f-promoted recruitment to atherosclerotic plaques.
2022 Scientific Article in Diabetes Care Diabetes Care 45, 837-844 (2022)
Costs of public health screening of children for presymptomatic type 1 diabetes in Bavaria, Germany.
2022 Review in Lancet Diabetes and Endocrinology Lancet Diabet. Endocrinol. 10, 221-230 (2022)
Sexual dimorphism in COVID-19: Potential clinical and public health implications.
2022 Scientific Article in Nature Immunology Nat. Immunol. 23, 411–422 (2022)
Normality sensing licenses local T cells for innate-like tissue surveillance.
2022 Review in Lancet Diabetes and Endocrinology Lancet Diabet. Endocrinol. 10, 284-296 (2022)
A global view of the interplay between non-alcoholic fatty liver disease and diabetes.
2022 Nature Genetics Nat. Genet. 54, 358-360 (2022)
EMPReSS: Standardized phenotype screens for functional annotation of the mouse genome (vol 37, pg 1155, 2005).
2022 Nature medicine Nat. Med. 28:599 (2022)
Author Correction: A combined risk score enhances prediction of type 1 diabetes among susceptible children.
2022 Letter to the Editor in Kidney International Kidney Int. 101, 649-650 (2022)
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An updated view on human neonatal thermogenesis.
2022 Scientific Article in Lancet Neurology, The Lancet Neurol. 21, 329-341 (2022)
Soluble TREM2 in CSF and its association with other biomarkers and cognition in autosomal-dominant Alzheimer's disease: A longitudinal observational study.
2022 Scientific Article in JACC: Cardiovascular Interventions JACC-Cardiovasc. Interv. 15, 618-626 (2022)
2-year results with a sirolimus-eluting self-expanding stent for femoropopliteal lesions: The first-in-human ILLUMINA study.
2022 Scientific Article in Allergy Allergy 77, 2482-2497 (2022)
Differential effects of lung inflammation on insulin resistance in humans and mice.
2022 Other: Opinion in Diabetes Care Diabetes Care 45, 273-275 (2022)
The brains behind SGLT2 inhibition.
2022 Scientific Article in Gut (eGut) Gut 71, 2463-2480 (2022)
Impairment of gut microbial biotin metabolism and host biotin status in severe obesity: Effect of biotin and prebiotic supplementation on improved metabolism.
2022 Scientific Article in Nature metabolism Nat. Metab. 4, 90–105 (2022)
Identification of a regulatory pathway inhibiting adipogenesis via RSPO2.
2022 Letter to the Editor in Pflügers Archiv Pflugers Arch. 474, 185-186 (2022)
MALDI MSI for a fresh view on atherosclerotic plaque lipids.
2022 Scientific Article in Cell Metabolism Cell Metab. 34, 329-345.e8 (2022)
Atlas of exercise metabolism reveals time-dependent signatures of metabolic homeostasis.
2022 Scientific Article in Diabetes Care Diabetes Care 45, 624-633 (2022)
Heterogeneity of DKA incidence and age-specific clinical characteristics in children diagnosed with type 1 diabetes in the TEDDY Study.
2022 Scientific Article in Journal of Cachexia, Sarcopenia and Muscle J. Cachexia Sarcopenia Muscle 13, 976-986 (2022)
Population-based cohort imaging: skeletal muscle mass by magnetic resonance imaging in correlation to bioelectrical-impedance analysis.
2022 Scientific Article in Cell Reports Cell Rep. 38:110270 (2022)
Gut HIF2α signaling is increased after VSG, and gut activation of HIF2α decreases weight, improves glucose, and increases GLP-1 secretion.
2022 Scientific Article in Developmental Cell Dev. Cell 57, 387-397.e4 (2022)
The Lipid Droplet Knowledge Portal: A resource for systematic analyses of lipid droplet biology.
2022 Scientific Article in Nature Methods Nat. Methods 19, 159–170 (2022)
CellRank for directed single-cell fate mapping.
2022 Review in Advanced Drug Delivery Reviews Adv. Drug Deliv. Rev. 181:114110 (2022)
Delivery of miRNAs to the adipose organ for metabolic health.
2022 Scientific Article in Diabetes Diabetes 71, 566-577 (2022)
Cytotoxicity-related gene expression and chromatin accessibility define a subset of CD4+ T cells that mark progression to type 1 diabetes.
2022 Scientific Article in Cardiovascular Diabetology Cardiovasc. Diabetol. 21:6 (2022)
Fetuin-A and risk of diabetes-related vascular complications: A prospective study.
2022 Scientific Article in Xenotransplantation Xenotransplantation 29:e12719 (2022)
Transgenic pigs expressing near infrared fluorescent protein-A novel tool for noninvasive imaging of islet xenotransplants.
2022 Scientific Article in Molecular Metabolism Mol. Metab. 56:101412 (2022)
Adipocyte-specific tribbles pseudokinase 1 regulates plasma adiponectin and plasma lipids in mice.
2022 Scientific Article in Pflügers Archiv Pflugers Arch. 474, 217-229 (2022)
Proteolytic activation of the epithelial sodium channel (ENaC) by factor VII activating protease (FSAP) and its relevance for sodium retention in nephrotic mice.
2022 Scientific Article in Cancers Cancers 14:90 (2022)
Aging aggravates cachexia in tumor-bearing mice.
2022 Scientific Article in Transplantation Proceedings Transplant. Proc. 54, 116-119 (2022)
Late onset cerebral nocardiosis in a sensitized renal transplant recipient following alemtuzumab induction: A case report.
2022 Scientific Article in Disease Models and Mechanisms Dis. Model. Mech. 15:dmm049205 (2022)
Post-synaptic scaffold protein TANC2 in psychiatric and somatic disease risk.
2022 Scientific Article in Cells Cells 11:28 (2022)
Enhancer RNA expression in response to glucocorticoid treatment in murine macrophages.
2022 Scientific Article in Clinical Cancer Research Clin. Cancer Res. 28, 1038-1052 (2022)
Therapy-related transcriptional subtypes in matched primary and recurrent head and neck cancer.
2022 Scientific Article in Cells Cells 11:42 (2022)
TNFα mediates inflammation-induced effects on PPARG splicing in adipose tissue and mesenchymal precursor cells.
2022 Scientific Article in American Journal of Physiology - Endocrinology and Metabolism Am. J. Physiol. Endocrinol. Metab. 322, E85-E100 (2022)
Susceptibility to diet-induced obesity at thermoneutral conditions is independent of UCP1.
2022 Review in Nature Reviews - Endocrinology Nat. Rev. Endocrinol. 18, 75-76 (2022)
Metabolic disorders, COVID-19 and vaccine-breakthrough infections.
2022 Other: News Item in Nature Reviews - Endocrinology Nat. Rev. Endocrinol. 18, 7-8 (2022)
Research in metabolic ageing - a tale of mice versus humans?
2022 Review in Nature Reviews - Endocrinology Nat. Rev. Endocrinol. 18, 79–80 (2022)
New insights into β-cell failure, regeneration and replacement.
2022 Review in Nature Reviews - Drug Discovery Nat. Rev. Drug Discov. 21, 201-223 (2022)
Anti-obesity drug discovery: Advances and challenges.
2022 Scientific Article in Human Molecular Genetics Hum. Mol. Genet. 31, 3367-3376 (2022)
First mitochondrial genome wide association study with metabolomics.
2022 Scientific Article in Diabetes Care Diabetes Care 45, 160-168 (2022)
Islet autoantibody type-specific titer thresholds improve stratification of risk of progression to type 1 diabetes in children.
2022 Scientific Article in Diabetes/Metabolism Research and Reviews Diabetes Metab. Res. Rev.:e3500 (2022)
Immune response differs between intralymphatic or subcutaneous administration of GAD-alum in individuals with recent onset type 1 diabetes.
2022 Scientific Article in Life Science Alliance Life Sci. All. 5:e202101164 (2022)
Bis-choline tetrathiomolybdate prevents copper-induced blood-brain barrier damage.
2022 Scientific Article in Diabetes Care Diabetes Care 45, 398-406 (2022)
Empagliflozin improves insulin sensitivity of the hypothalamus in humans with prediabetes: A randomized, double-blind, placebo-controlled, phase 2 trial.
2022 Editorial in Gut (eGut) Gut 71, 2147-2148 (2022)
Is epiploic fat the dermal fat of the intestine?
2022 Scientific Article in Diabetologie, Die Diabetologie 18, 77-86 (2022)
Laboratory diagnostics of people with diabetes.
2022 Diabetologia Diabetologia 65:257 (2022)
Correction to: Neuron-specific biomarkers predict hypo- and hyperalgesia in individuals with diabetic peripheral neuropathy.
2022 Review in Nature Reviews - Endocrinology Nat. Rev. Endocrinol. 18, 43–54 (2022)
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2022 Scientific Article in Cell Death and Differentiation Cell Death Differ., DOI: 10.1038/s41418-021-00883-z (2022)
MS4A15 drives ferroptosis resistance through calcium-restricted lipid remodeling.
2022 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 107, e582-e593 (2022)
Distinct and convergent beneficial effects of estrogen and insulin on cognitive function in healthy young men.
2022 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 107, e836-e851 (2022)
Expression of the adipocyte progenitor markers MSCA1 and CD36 is associated with adipose tissue function in children.
2022 Scientific Article in ISME Journal ISME J. 16, 211–220 (2022)
Evidence for methanobactin "Theft" and novel chalkophore production in methanotrophs: Impact on methanotrophic-mediated methylmercury degradation.
2022 Scientific Article in Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet. 130, 17-21 (2022)
Influence of spinal cord stimulation on insulin sensitivity in chronic pain patients.
2022 Scientific Article in Radiation Research Radiat. Res. 197, 67-77 (2022)
Complex long-term effects of radiation on adult mouse behaviour.
2022 Scientific Article in Neuropathology and Applied Neurobiology Neuropathol. Appl. Neurobiol. 48:e12750 (2022)
N471D WASH complex subunit strumpellin knock-in mice display mild motor and cardiac abnormalities and BPTF and KLHL11 dysregulation in brain tissue.
2022 Scientific Article in Acta Pharmacologica Sinica Acta Pharmacol. Sin. 43, 111-120 (2022)
Renal effects of the serine protease inhibitor aprotinin in healthy conscious mice.
2022 Scientific Article in Radiation Research Radiat. Res. 197, 7-21 (2022)
On the nature of murine radiation-induced subcapsular cataracts: Optical coherence tomography-based fine classification, in vivo dynamics and impact on visual acuity.
2022 Scientific Article in Epigenetics Epigenetics 17, 19-31 (2022)
Maternal haemoglobin levels in pregnancy and child DNA methylation: A study in the pregnancy and childhood epigenetics consortium.
2022 Review in Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet. 130, 200-204 (2022)
Considering insulin secretory capacity as measured by a fasting c-peptide/glucose ratio in selecting glucose-lowering medications.
2022 Scientific Article in Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet. 130, 43-48 (2022)
The TUDID Study - background and design of a prospective cohort.
Masterclass in Neuroendocrinology In: Neuroanatomy of Neuroendocrine Systems. 2021. 317-346 (Mast. Neuroend. ; 12)
The Neuroanatomical Organization of Hypothalamic Feeding Circuits.
Masterclass in Neuroendocrinology In: Glial-Neuronal Signaling in Neuroendocrine Systems. 2021. 127-154 (Mast. Neuroend. ; 11)
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2021 Scientific Article in AMIA Annual Symposium Proceedings AMIA Annu. Symp. Proc. 2021, 754-762 (2021)
Imputing longitudinal growth data in international pediatric studies: Does CDC reference suffice?
2021 Scientific Article in Frontiers in Global Women's Health Front. Glob. Womens Health 2:807817 (2021)
Association between objectively assessed sleep and depressive symptoms during pregnancy and post-partum.
2021 Molecular Systems Biology Mol. Syst. Biol. 17:e10851 (2021)
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CDKN1B (p27) defects leading to pituitary tumors.
München, Technische Universität, TUM School of Life Sciences, Diss., 2021, 156 S.
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2021 Review in Hormone Research in Paediatrics Horm. Res. Paediatr. 96, 88-96 (2021)
Stress, stress reduction and obesity in childhood and adolescence.
2021 Scientific Article in Breast Cancer Research Breast Cancer Res. 23:86 (2021)
Association of germline genetic variants with breast cancer-specific survival in patient subgroups defined by clinic-pathological variables related to tumor biology and type of systemic treatment.
2021 Scientific Article in Scientific Reports Sci. Rep. 11:19787 (2021)
Germline variants and breast cancer survival in patients with distant metastases at primary breast cancer diagnosis.
2021 Scientific Article in Nature Nature 600, 500-505 (2021)
Combinatorial, additive and dose-dependent drug-microbiome associations.
2021 Review in Biomedicines Biomedicines 9:1853 (2021)
The role of physical activity in nonalcoholic and metabolic dysfunction associated fatty liver disease.
2021 Scientific Article in PLoS ONE PLoS ONE 16:e0261564 (2021)
Course of lactate, pH and base excess for prediction of mortality in medical intensive care patients.
2021 Scientific Article in Life Life 11:1393 (2021)
Physiological doses of hydroxytyrosol modulate gene expression in skeletal muscle of exercised rats.
2021 Review in Frontiers in Endocrinology Front. Endocrin. 12:765201 (2021)
Diabetic pneumopathy-a new diabetes-associated complication: Mechanisms, consequences and treatment considerations.
2021 Review in EJNMMI Research EJNMMI Res. 11:121 (2021)
Imaging pheochromocytoma in small animals: Preclinical models to improve diagnosis and treatment.
2021 Review in Reviews in Endocrine & Metabolic Disorders Rev. Endocr. Metab. Disord., DOI: 10.1007/s11154-021-09697-3 (2021)
Neurobiological regulation of eating behavior: Evidence based on non-invasive brain stimulation.
2021 Scientific Article in New England Journal of Medicine, The / NEJM N. Engl. J. Med. 385, 1451-1461 (2021)
Empagliflozin in heart failure with a preserved ejection fraction.
2021 Scientific Article in New England Journal of Medicine, The / NEJM N. Engl. J. Med. 385, 2252-2263 (2021)
Cardiovascular events with finerenone in kidney disease and type 2 diabetes.
2021 Scientific Article in Frontiers in Physiology Front. Physiol. 12:724755 (2021)
Muscle fatigue revisited - Insights from optically pumped magnetometers.
2021 Scientific Article in Journal of Immunology J. Immunol. 207, 3081-3089 (2021)
Myeloid cell-specific IL-4 receptor knockout partially protects from adipose tissue inflammation.
2021 Review in Med (N Y) Med. 2, 1138-1162 (2021)
Charting the next century of insulin replacement with cell and gene therapies.
2021 Scientific Article in Patient Education and Counseling Patient Educ. Couns. 105, 2158-2165 (2021)
Efficacy of DiaLife, an education program for relatives of adult patients with diabetes - study protocol of a cluster randomized controlled trial.
2021 Scientific Article in Frontiers in Endocrinology Front. Endocrin. 12:778875 (2021)
m6A regulators in human adipose tissue - depot-specificity and correlation with obesity.
2021 Review in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 16, 473-475 (2021)
Veranlagung und Lebensstil – die Komplexität des Diabetes mellitus – Langerhans-Medaille 2021 – eine Kurzübersicht über den Preisträger Martin Hrabě de Angelis.
2021 Scientific Article in Nature metabolism Nat. Metab. 3, 1662-1679 (2021)
Insulin signalling in tanycytes gates hypothalamic insulin uptake and regulation of AgRP neuron activity.
2021 Review in Cancer and Metastasis Reviews Cancer Metastasis Rev., DOI: 10.1007/s10555-021-10007-1 (2021)
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2021 Scientific Article in Science Advances Sci. Adv. 7:eabb3673 (2021)
Phenotypic drug screening in a human fibrosis model identified a novel class of antifibrotic therapeutics.
2021 Scientific Article in Viruses Viruses 13:2537 (2021)
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2021 Scientific Article in Nature Nature 600, 720–726 (2021)
A hormone complex of FABP4 and nucleoside kinases regulates islet function.
2021 Scientific Article in Cells Cells 10:3443 (2021)
Tgf-β induction of mir-143/145 is associated to exercise response by influencing differentiation and insulin signaling molecules in human skeletal muscle.
2021 Review in Diabetes Aktuell Diabetes akt. 19, 318-322 (2021)
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2021 Scientific Article in International Journal of Molecular Sciences Int. J. Mol. Sci. 22:12695 (2021)
Cardioprotective effects of palmitoleic acid (C16:1n7) in a mouse model of catecholamine-induced cardiac damage are mediated by PPAR activation.
2021 Scientific Article in International Journal of Molecular Sciences Int. J. Mol. Sci. 22:12526 (2021)
Synaptotagmin-13 is a neuroendocrine marker in brain, intestine and pancreas.
2021 Review in Journal of Cellular Biochemistry J. Cell. Biochem., DOI: 10.1002/jcb.30179 (2021)
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2021 Scientific Article in Cell Reports Medicine Cell Rep. Med. 2:100434 (2021)
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2021 Scientific Article in BMC Genomics BMC Genomics 22:802 (2021)
Phenotype-tissue expression and exploration (PTEE) resource facilitates the choice of tissue for RNA-seq-based clinical genetics studies.
2021 Scientific Article in PLoS ONE PLoS ONE 16:e0259629 (2021)
A new mathematical approach to improve the original dietary inflammatory index (DII) calculation.
2021 Scientific Article in BMJ Open BMJ Open 11:e052449 (2021)
Supplementation with Bifidobacterium longum subspecies infantis EVC001 for mitigation of type 1 diabetes autoimmunity: the GPPAD-SINT1A randomised controlled trial protocol.
2021 Scientific Article in JCI insight JCI insight 6:e146999 (2021)
Detection of diabetes from whole-body MRI using deep learning.
2021 Scientific Article in Hippocampus Hippocampus, DOI: 10.1002/hipo.23392 (2021)
Unfolding of spatial representation at systems level in infant rats.
2021 Editorial in Diabetologie, Die Diabetologie 17, 777-779 (2021)
Mit Big Data zu einer gezielteren Diabetes-Prävention und -Therapie.
2021 Review in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 16, S215-S225 (2021)
Gestationsdiabetes mellitus (GDM), Diagnostik, Therapie und Nachsorge-Kurzfassung der S3-Leitlinie (AWMF-Registernummer: 057-008).
2021 Review in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 16, S308-S311 (2021)
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2021 Review in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 16, S312-S318 (2021)
Lipidtherapie bei Patienten mit Diabetes mellitus-Eine gemeinsame Stellungnahme der Kommission Fettstoffwechsel sowie der AG Herz und Diabetes der Deutschen Diabetes Gesellschaft (DDG), der Sektion Diabetes, Adipositas und Stoffwechsel der Deutschen Gesellschaft für Endokrinologie (DGE), der AG Herz und Diabetes der Deutschen Gesellschaft für Kardiologie (DGK) und der gemeinsamen AG Herz-Hormone-Diabetes der DGK, DGE und DDG.
2021 Review in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 16, S319-S323 (2021)
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2021 Scientific Article in LAB on a chip Lab Chip 21, 4685-4695 (2021)
Automated optimization of endoderm differentiation on chip.
2021 Scientific Article in Frontiers in Medicine Front. Med. 8:751277 (2021)
Differential effects of insulin-deficient diabetes mellitus on visceral vs. subcutaneous adipose tissue-multi-omics insights from the Munich MIDY pig model.
2021 Other: Opinion in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 16, 369-371 (2021)
"A Pragmatic, Randomized Clinical Trial of Gestational Diabetes Screening"-eine interdisziplinäre Stellungnahme.
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2021 Scientific Article in Faculty of 1000 Research F1000 Res. 10:456 (2021)
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2021 Scientific Article in Nature Communications Nat. Commun. 12:6883 (2021)
Dietary essential amino acids restore liver metabolism in ovariectomized mice via hepatic estrogen receptor α.
2021 Scientific Article in Cell Reports Cell Rep. 37:110003 (2021)
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2021 Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet. 129, e1 (2021)
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2021 Scientific Article in Molecular Cell Mol. Cell 81, 4810-4825.e12 (2021)
Balancing of mitochondrial translation through METTL8-mediated m3C modification of mitochondrial tRNAs.
2021 Scientific Article in Peptides Peptides 146:170677 (2021)
Calcitonin gene-related peptide exerts inhibitory effects on autophagy in the heart of mice.
2021 Scientific Article in European Eating Disorders Review Eur. Eat. Disord. Rev., DOI: 10.1002/erv.2870 (2021)
Maternal eating disorder severity is associated with increased latency of foetal auditory event-related brain responses.
2021 Scientific Article in PLoS ONE PLoS ONE 16:e0258476 (2021)
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2021 Scientific Article in Biomedicines Biomedicines 9:1452 (2021)
Chip-based sensing of the intercellular transfer of cell surface proteins: Regulation by the metabolic state.
2021 Scientific Article in Journal of Comparative Physiology A: Neuroethology, Sensory, Neural, and Behavioral Physiology J. Comp. Physiol. A -Neuroethol. Sens. Neural Behav. Physiol., DOI: 10.1007/s00359-021-01506-1 (2021)
Localisation of cryptochrome 2 in the avian retina.
2021 Scientific Article in Frontiers in Oncology Front. Oncol. 11:755746 (2021)
The missing link: Cre pigs for cancer research.
2021 Scientific Article in Cell Reports Medicine Cell Rep. Med. 2:100407 (2021)
AdipoAtlas: A reference lipidome for human white adipose tissue.
2021 Scientific Article in Molecular Metabolism Mol. Metab. 54:101359 (2021)
Exercise prevents fatty liver by modifying the compensatory response of mitochondrial metabolism to excess substrate availability.
2021 Scientific Article in ESC heart failure ESC Heart Fail., DOI: 10.1002/ehf2.13713 (2021)
Non-targeted metabolomics identify polyamine metabolite acisoga as novel biomarker for reduced left ventricular function.
2021 Scientific Article in Disease Models and Mechanisms Dis. Model. Mech. 14:dmm049285 (2021)
A scalable, clinically severe pig model for Duchenne muscular dystrophy.
2021 Scientific Article in Analytical Chemistry Anal. Chem. 93, 16369-16378 (2021)
Cross-laboratory standardization of preclinical lipidomics using differential mobility spectrometry and multiple reaction monitoring.
2021 Scientific Article in Frontiers in Nutrition Front. Nutr. 8:741249 (2021)
Leptin receptor-deficient db/db mice show significant heterogeneity in response to high non-heme iron diet.
2021 Scientific Article in European Journal of Nutrition Eur. J. Nutr., DOI: 10.1007/s00394-021-02687-w (2021)
Interplay between adipose tissue secreted proteins, eating behavior and obesity.
2021 Scientific Article in Frontiers in Endocrinology Front. Endocrin. 12:739021 (2021)
Role of ubiquilins for brown adipocyte proteostasis and thermogenesis.
2021 Scientific Article in Scientific Reports Sci. Rep. 11:20306 (2021)
Slow deep breathing modulates cardiac vagal activity but does not affect peripheral glucose metabolism in healthy men.
2021 Scientific Article in Cell Metabolism Cell Metab. 33, 2398-2414.e9 (2021)
Mitochondrial metabolism coordinates stage-specific repair processes in macrophages during wound healing.
2021 Scientific Article in Nature Communications Nat. Commun. 12:6486 (2021)
Elevated circulating follistatin associates with an increased risk of type 2 diabetes.
2021 Scientific Article in Nature Communications Nat. Commun. 12:6625 (2021)
scPower accelerates and optimizes the design of multi-sample single cell transcriptomic studies.
2021 Review in Obesity Reviews Obes. Rev., DOI: 10.1111/obr.13372 (2021)
The incretin/glucagon system as a target for pharmacotherapy of obesity.
2021 Scientific Article in Molecular Systems Biology Mol. Syst. Biol. 17:e10387 (2021)
COVID19 Disease Map, a computational knowledge repository of virus–host interaction mechanisms.
2021 Scientific Article in Molecular Metabolism Mol. Metab. 54:101348 (2021)
Leptin counteracts hypothermia in hypothyroidism through its pyrexic effects and by stabilizing serum thyroid hormone levels.
2021 Review in Med (N Y) Med. 2, 1120-1137 (2021)
100 Years of insulin: Lifesaver, immune target, and potential remedy for prevention.
2021 Scientific Article in Zentralblatt für Chirurgie Zent.bl. Chir. 146, 597-604 (2021)
SARS-CoV-2-Infektionen und klinische Konsequenzen bei organtransplantierten Patienten im Rahmen der ersten Ansteckungswelle in Deutschland - eine monozentrische Umfrage und ein Fallbericht.
2021 Scientific Article in Gut (eGut) Gut, DOI: 10.1136/gutjnl-2021-324603 (2021)
Multiomics reveal unique signatures of human epiploic adipose tissue related to systemic insulin resistance.
2021 Scientific Article in Frontiers in Nutrition Front. Nutr. 8:720041 (2021)
25(OH)D levels in infancy is associated with celiac disease autoimmunity in at-risk children: A case-control study.
2021 Scientific Article in Scientific Reports Sci. Rep. 11:19609 (2021)
A newly developed and externally validated non-clinical score accurately predicts 10-year cardiovascular disease risk in the general adult population.
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A binary classification model for toxicity prediction in drug design.
2021 Review in Cell and Tissue Research Cell Tissue Res., DOI: 10.1007/s00441-021-03539-z (2021)
P75 neurotrophin receptor controls subventricular zone neural stem cell migration after stroke.
2021 Review in Nutrients Nutrients 13:3999 (2021)
Impact of exercise on gut microbiota in obesity.
2021 Scientific Article in EMBO Molecular Medicine EMBO Mol. Med.:e14397 (2021)
Characterising a homozygous two-exon deletion in UQCRH: Comparing human and mouse phenotypes.
2021 Review in EJNMMI Research EJNMMI Res. 11:94 (2021)
Imaging modalities for diagnosis and monitoring of cancer cachexia.
2021 Review in Journal of Physiology - London J. Physiol.-London, DOI: 10.1113/JP281979 (2021)
Adipocyte function and the development of cardiometabolic disease.
2021 Scientific Article in Frontiers in Endocrinology Front. Endocrin. 12:722656 (2021)
Plasma metabolome profiling for the diagnosis of catecholamine producing tumors.
2021 Scientific Article in Genes Genes 12:1732 (2021)
Distinct morphological and behavioural alterations in ENU-induced heterozygous Trpc7K810stop mutant mice.
2021 Review in Nature Reviews - Endocrinology Nat. Rev. Endocrinol., DOI: 10.1038/s41574-021-00577-z (2021)
Is the association between diabetes mellitus and pulmonary fibrosis real?
2021 Scientific Article in Radiology Radiology 302, 153-161 (2021)
Diffusion MRI in peripheral nerves: Optimized b values and the role of non-Gaussian diffusion.
2021 Editorial in Frontiers in Endocrinology Front. Endocrin. 12:767012 (2021)
Editorial: Footprints of immune cells in the type 1 diabetic pancreas.
2021 Scientific Article in Nature metabolism Nat. Metab. 3, 1415-1431 (2021)
Small extracellular vesicle-mediated targeting of hypothalamic AMPKα1 corrects obesity through BAT activation.
2021 Scientific Article in Scientific Reports Sci. Rep. 11:19400 (2021)
Adipose expression of CREB3L3 modulates body weight during obesity.
2021 Scientific Reports Sci. Rep. 11:20089 (2021)
Author Correction: Adipose expression of CREB3L3 modulates body weight during obesity (Scientific Reports, (2021), 11, 1, (19400), 10.1038/s41598-021-98627-z).
2021 Scientific Article in Life Science Alliance Life Sci. All. 4:e202101013 (2021)
Functional and metabolic fitness of human CD4+ T lymphocytes during metabolic stress.
2021 Other: Opinion in JAMA network open JAMA net. open 4:e2128047 (2021)
Nonnutritive sweeteners and neural reward response in women and Iidividuals with obesity.
2021 Review in Lancet Diabetes and Endocrinology Lancet Diabet. Endocrinol. 9, 786-798 (2021)
COVID-19 and metabolic disease: Mechanisms and clinical management.
2021 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 106, 2949-2961 (2021)
Central insulin modulates dopamine signaling in the human striatum.
2021 Scientific Article in Deutsches Ärzteblatt international Dtsch. Arztebl. Int. 118, 629-636 (2021)
Blutglukoseziele in der operativen Intensivmedizin.
2021 Nature metabolism Nat. Metab. 3:1433 (2021)
Publisher Correction: Revisiting energy expenditure: How to correct mouse metabolic rate for body mass.
2021 Review in Metabolites Metabolites 11:732 (2021)
Astrocyte gliotransmission in the regulation of systemic metabolism.
2021 Review in Diabetologie, Die Diabetologie 17, 780–787 (2021)
DZDconnect: Using connected data to fight diabetes.
2021 Scientific Article in STAR Protocols STAR Protoc. 2:100805 (2021)
Purification of GFP-tagged nuclei from frozen livers of INTACT mice for RNA- and ATAC-sequencing.
2021 Review in Physiology Physiology 36, 350-358 (2021)
Role of mTor signaling for tubular function and disease.
2021 Scientific Article in Diabetes, Obesity and Metabolism Diabetes Obes. Metab., DOI: 10.1111/dom.14549 (2021)
Switching the basal insulin to insulin glargine 300 U/ml in people with type 2 diabetes under basal insulin supported oral therapy: Observational trial on effectiveness and safety.
2021 Scientific Article in Transplantation Proceedings Transplant. Proc. 53, 2421-2434 (2021)
SARS-CoV-2 in solid organ transplant recipients: A structured review of 2020.
2021 Scientific Article in Nutrients Nutrients 13:3286 (2021)
The effect of dietary protein imbalance during pregnancy on the growth, metabolism and circulatory metabolome of neonatal and weaned juvenile porcine offspring.
2021 Scientific Article in Molecular Metabolism Mol. Metab. 54:101341 (2021)
Oncostatin M suppresses browning of white adipocytes via gp130-STAT3 signaling.
2021 Scientific Article in International Journal of Molecular Sciences Int. J. Mol. Sci. 22:9979 (2021)
A novel uplc-ms/ms method identifies organ-specific dipeptide profiles.
2021 Scientific Article in Kidney International Kidney Int. 100, 1227-1239 (2021)
Proteinuric chronic kidney disease is associated with altered red blood cell lifespan, deformability and metabolism.
2021 Scientific Article in BMC Pregnancy and Childbirth BMC Pregnancy Childbirth 21:628 (2021)
Acute relaxation during pregnancy leads to a reduction in maternal electrodermal activity and self-reported stress levels.
2021 Scientific Article in Endocrine Endocrine, DOI: 10.1007/s12020-021-02858-z (2021)
Pre- versus post-operative untargeted plasma nuclear magnetic resonance spectroscopy metabolomics of pheochromocytoma and paraganglioma.
2021 Scientific Article in PLoS Medicine PLoS Med. 18:e1003786 (2021)
The blood metabolome of incident kidney cancer: A case-control study nested within the MetKid consortium.
2021 Scientific Article in Neurochemistry International Neurochem. Int. 150:105174 (2021)
Determination of morphine and norlaudanosoline in murine brain regions by dispersive liquid-liquid micro-extraction and liquid chromatograpy-electrochemical detection.
2021 Scientific Article in Proceedings of the National Academy of Sciences of the United States of America Proc. Natl. Acad. Sci. U.S.A. 118:e2107665118 (2021)
Sequential in vivo labeling of insulin secretory granule pools in INS-SNAP transgenic pigs.
2021 Scientific Article in Journal of the American Society of Nephrology J. Am. Soc. Nephrol. 32, 3066-3079 (2021)
CHOP-ASO ameliorates glomerular and tubular damage on top of ACE inhibition in diabetic kidney disease.
2021 Review in Endocrine Reviews Endocr. Rev., DOI: 10.1210/endrev/bnab025 (2021)
Arcuate nucleus-dependent regulation of metabolism - pathways to obesity and diabetes mellitus.
2021 Scientific Article in ESC heart failure ESC Heart Fail., DOI: 10.1002/ehf2.13607 (2021)
Human myocardial mitochondrial oxidative capacity is impaired in mild acute heart transplant rejection.
2021 Scientific Article in Diabetologia Diabetologia, DOI: 10.1007/s00125-021-05562-9 (2021)
Rivaroxaban compared with low-dose aspirin in individuals with type 2 diabetes and high cardiovascular risk: A randomised trial to assess effects on endothelial function, platelet activation and vascular biomarkers.
2021 Scientific Article in Molecular Metabolism Mol. Metab. 54:101330 (2021)
Vertical sleeve gastrectomy triggers fast β-cell recovery upon overt diabetes.
2021 Editorial in Frontiers in Endocrinology Front. Endocrin. 12:757539 (2021)
Editorial: Intermittent fasting - mechanisms and clinical usefulness.
2021 Review in Biomolecules Biomolecules 11:1426 (2021)
Obesity–an update on the basic pathophysiology and review of recent therapeutic advances.
2021 Scientific Article in Cancers Cancers 13:4433 (2021)
Mri‐determined psoas muscle fat infiltration correlates with severity of weight loss during cancer cachexia.
2021 Scientific Article in Diabetologia Diabetologia, DOI: 10.1007/s00125-021-05557-6 (2021)
Neuron-specific biomarkers predict hypo- and hyperalgesia in individuals with diabetic peripheral neuropathy.
2021 Scientific Article in Nature Communications Nat. Commun. 12:5208 (2021)
Defining the RBPome of primary T helper cells to elucidate higher-order Roquin-mediated mRNA regulation.
2021 Scientific Article in Science Advances Sci. Adv. 7:eabi7828 (2021)
Integration of feeding behavior by the liver circadian clock reveals network dependency of metabolic rhythms.
2021 Scientific Article in Life Science Alliance Life Sci. All. 4:e202101037 (2021)
RNA sequencing reveals niche gene expression effects of beta-hydroxybutyrate in primary myotubes.
2021 Scientific Article in STAR Protocols STAR Protoc. 2:100700 (2021)
A laser-mediated photo-manipulative toolbox for generation and real-time monitoring of DNA lesions.
2021 Scientific Article in American Journal of Physiology - Renal Physiology Am. J. Physiol.-Renal Physiol. 321, F480-F493 (2021)
Experimental nephrotic syndrome leads to proteolytic activation of the epithelial sodium channel (ENaC) in the mouse kidney.
2021 Scientific Article in Learning and Memory Learn. Mem. 28, 307-318 (2021)
The effect of zolpidem on targeted memory reactivation during sleep.
2021 Scientific Article in Journal of Lipid Research J. Lipid Res. 62:100105 (2021)
A novel compound heterozygous leptin receptor mutation causes more severe obesity than in Leprdb/db mice.
2021 Scientific Article in Journal of Cachexia, Sarcopenia and Muscle J. Cachexia Sarcopenia Muscle, DOI: 10.1002/jcsm.12758 (2021)
Association of circulating PLA2G7 levels with cancer cachexia and assessment of darapladib as a therapy.
2021 Scientific Article in Disease Models and Mechanisms Dis. Model. Mech. 14:dmm049038 (2021)
Essential role of DNA-PKcs and plasminogen for the development of doxorubicin-induced glomerular injury in mice.
2021 Scientific Article in Nature metabolism Nat. Metab. 3, 1202-1216 (2021)
Diet-induced alteration of intestinal stem cell function underlies obesity and prediabetes in mice.
2021 Scientific Article in Journal of Clinical Investigation J. Clin. Invest. 131:e142202 (2021)
Hyperexcitable interneurons trigger cortical spreading depression in an Scn1a migraine model.
2021 Scientific Article in Nature Communications Nat. Commun. 12:5068 (2021)
O-GlcNAcylated p53 in the liver modulates hepatic glucose production.
2021 Scientific Article in Diabetes Diabetes 70, 2785-2795:2785-2795 (2021)
Different effects of lifestyle intervention in high- and low-risk prediabetes.
2021 Scientific Article in Radiation Oncology Radiat. Oncol. 16:159 (2021)
Development of a model for fibroblast-led collective migration from breast cancer cell spheroids to study radiation effects on invasiveness.
2021 Scientific Article in The CRISPR Journal CRISPR J. 4, 491-501 (2021)
Increasing gene editing efficiency for CRISPR-Cas9 by small RNAs in pluripotent stem cells.
2021 Scientific Article in Internist, Der Internist 62, 998-1002 (2021)
Therapie der Adipositas mit Semaglutid.
2021 Scientific Article in Scientific Reports Sci. Rep. 11:16642 (2021)
Free fatty acids, glicentin and glucose-dependent insulinotropic polypeptide as potential major determinants of fasting substrate oxidation.
2021 Scientific Article in EMBO Molecular Medicine EMBO Mol. Med. 13:e13490 (2021)
Functional multispectral optoacoustic tomography imaging of hepatic steatosis development in mice.
2021 Scientific Article in Nature Communications Nat. Commun. 12:4957 (2021)
Offspring born to influenza A virus infected pregnant mice have increased susceptibility to viral and bacterial infections in early life.
2021 Scientific Article in Nature metabolism Nat. Metab., DOI: 10.1038/s42255-021-00451-2 (2021)
Revisiting energy expenditure: How to correct mouse metabolic rate for body mass.
2021 Review in Nature Reviews - Drug Discovery Nat. Rev. Drug Discov. 20, 920–940 (2021)
Engineering islets from stem cells for advanced therapies of diabetes.
2021 Review in Metabolites Metabolites 11:474 (2021)
Signals from the circle: Tricarboxylic acid cycle intermediates as myometabokines.
2021 Nature Communications Nat. Commun. 12:4796 (2021)
Author Correction: Glucose homeostasis is regulated by pancreatic β-cell cilia via endosomal EphA-processing.
2021 Scientific Article in Diabetologia Diabetologia, DOI: 10.1007/s00125-021-05523-2 (2021)
Simplifying prediction of disease progression in pre-symptomatic type 1 diabetes using a single blood sample.
2021 Scientific Article in The journal of experimental biology J. Exp. Biol. 224:jeb242431 (2021)
Sleep and conditioning of the siphon withdrawal reflex in Aplysia.
2021 Scientific Article in Analytical Chemistry Anal. Chem. 93, 10916-10924 (2021)
Systematic, modifying group-assisted strategy expanding coverage of metabolite annotation in liquid chromatography-mass spectrometry-based nontargeted metabolomics studies.
2021 Scientific Article in Journal of Pharmaceutical and Biomedical Analysis : JPBA J. Pharm. Biomed. Anal. 205:114288 (2021)
Comparison of the metabolome in urine prior and eight weeks after radical prostatectomy uncovers pathologic and molecular features of prostate cancer.
2021 Review in Mammalian Genome Mamm. Genome, DOI: 10.1007/s00335-021-09892-2 (2021)
INFRAFRONTIER quality principles in systemic phenotyping.
2021 Review in Cells Cells 10:1822 (2021)
A narrative review on the role of AMPK on de novo lipogenesis in non-alcoholic fatty liver disease: Evidence from human studies.
2021 Scientific Article in Deutsches Ärzteblatt international Dtsch. Arztebl. Int. 118, 407-412 (2021)
Diabetes in the Hospital.
2021 Scientific Article in Molecular Metabolism Mol. Metab. 54:101334 (2021)
A point mutation in the Pdia6 gene results in loss of pancreatic β-cell identity causing overt diabetes.
2021 Scientific Article in British Journal of Pharmacology Br. J. Pharmacol., DOI: 10.1111/bph.15630 (2021)
Approved drugs ezetimibe and disulfiram enhance mitochondrial Ca2+ uptake and suppress cardiac arrhythmogenesis.
2021 Scientific Article in European Journal of Radiology Eur. J. Radiol. 142:109864 (2021)
Contrast-enhanced MRI for simultaneous evaluation of renal morphology and split renal function in living kidney donor candidates.
2021 Scientific Article in Deutsches Ärzteblatt international Dtsch. Arztebl. Int. 118, 432-433 (2021)
HbA1c measurement cannot replace an oral glucose tolerance test for the diagnosis of gestational diabetes.
2021 Other: Opinion in Nature Nature 597, 39-40 (2021)
A brain signal that coordinates thought with metabolism.
2021 Editorial in Frontiers in Endocrinology Front. Endocrin. 12:739065 (2021)
Editorial: Brown adipose tissue: From heat production in rodents to metabolic health in humans.
2021 Editorial in EMBO Molecular Medicine EMBO Mol. Med.:e14618 (2021)
Fuse your mitochondria, lose appetite: An anorexic, anti-obesity sphingolipid.
2021 Scientific Article in International Journal of Molecular Sciences Int. J. Mol. Sci. 22:7958 (2021)
Common muscle metabolic signatures highlight arginine and lysine metabolism as potential therapeutic targets to combat unhealthy aging.
2021 Review in Advanced science Adv. Sci., e2100275 (2021)
Emerging targets in type 2 diabetes and diabetic complications.
2021 Scientific Article in Diabetologia Diabetologia 64, 2247-2257 (2021)
Characteristics of children diagnosed with type 1 diabetes before vs after 6 years of age in the TEDDY cohort study.
2021 Scientific Article in Coatings Coatings 11:838 (2021)
Anethum graveolens prevents liver and kidney injury, oxidative stress and inflammation in mice exposed to nicotine perinatally.
2021 Scientific Article in Deutsches Ärzteblatt international Dtsch. Arztebl. Int. 118, 367-372 (2021)
Diabetic ketoacidosis at manifestation of type 1 diabetes in childhood and adolescence.
2021 Scientific Article in European Journal of Radiology Eur. J. Radiol. 142:109845 (2021)
Quantification of liver and muscular fat using contrast-enhanced Dual Source Dual Energy Computed Tomography compared to an established multi-echo Dixon MRI sequence.
2021 Scientific Article in Acta Diabetologica Acta Diabetol., DOI: 10.1007/s00592-021-01772-0 (2021)
Dose-dependent effects of insoluble fibre on glucose metabolism: A stratified post hoc analysis of the Optimal Fibre Trial (OptiFiT).
2021 Scientific Article in Environment International Environ. Int. 156:106730 (2021)
Alternatives for the worse: Molecular insights into adverse effects of bisphenol a and substitutes during human adipocyte differentiation.
2021 Scientific Article in Nutrients Nutrients 13:2499 (2021)
Leptin improves parameters of brown adipose tissue thermogenesis in lipodystrophic mice.
2021 Scientific Article in European Journal of Heart Failure Eur. J. Heart Fail. 23, 1633-1644 (2021)
Proteomics to improve phenotyping in obese patients with heart failure with preserved ejection fraction.
2021 Nature Communications Nat. Commun. 12:4528 (2021)
Publisher Correction: Cellular and physiological circadian mechanisms drive diurnal cell proliferation and expansion of white adipose tissue.
2021 Review in Monatsschrift Kinderheilkunde Mon.schr. Kinderheilkd. 169, 922–929 (2021)
Nicht immer Typ 1 – seltene Diabetesformen bei Kindern.
2021 Nature Communications Nat. Commun. 12:4521 (2021)
Author Correction: PDX1LOW MAFALOW β-cells contribute to islet function and insulin release.
2021 Nature Cell Biology Nat. Cell Biol., DOI: 10.1038/s41556-021-00735-5 (2021)
Publisher Correction: Epithelial cell plasticity drives endoderm formation during gastrulation.
2021 Scientific Article in Diabetes Diabetes 70, 2092-2106 (2021)
Profiles of glucose metabolism in different prediabetes phenotypes, classified by fasting glycemia, 2-hour OGTT, glycated hemoglobin, and 1-hour OGTT: An IMI DIRECT study.
2021 Scientific Article in Cell Metabolism Cell Metab. 33, 1685-1700.e9 (2021)
Liver-fibrosis-activated transcriptional networks govern hepatocyte reprogramming and intra-hepatic communication.
2021 Scientific Article in NeuroImage - a Journal of Brain Function Neuroimage 240:118378 (2021)
Dynamics of nonlinguistic statistical learning: From neural entrainment to the emergence of explicit knowledge.
2021 Scientific Article in Journal of Nephrology J. Nephrol. 35, 311–316 (2021)
Intraperitoneal extension of the peritoneal dialysis catheter-a new technique for catheter implantation in patients with obesity.
2021 Scientific Article in Scientific Reports Sci. Rep. 11:13333 (2021)
The highly conserved FOXJ1 target CFAP161 is dispensable for motile ciliary function in mouse and Xenopus.
2021 Scientific Article in Metabolites Metabolites 11:405 (2021)
Respiratory parameters for the classification of dysfunctional insulin secretion by pancreatic islets.
2021 Scientific Article in Antioxidants Antioxidants 10:1103 (2021)
Nox4 maintains blood pressure during low sodium diet.
2021 Scientific Article in Transplant international Transpl. Int. 34, 1959-1970 (2021)
Dynamics of glucose metabolism after liver transplantation: Prediabetes as a window of opportunity for patient survival and long-term kidney function.
2021 Scientific Article in Frontiers in Molecular Biosciences Front. Mol. Biosci. 8:689799 (2021)
Whole-slide image analysis of human pancreas samples to elucidate the immunopathogenesis of type 1 diabetes using the QuPath software.
2021 Journal of Nutritional Biochemistry, The J. Nutr. Biochem. 97:108807 (2021)
Corrigendum to "Dietary protein dilution limits dyslipidemia in obesity through FGF21-driven fatty acid clearance" [The Journal of Nutritional Biochemistry 57 (2018) 189-196].
2021 Review in Frontiers in Immunology Front. Immunol. 12:683091 (2021)
Means, motive, and opportunity: Do non-islet-reactive infiltrating T cells contribute to autoimmunity in type 1 diabetes?
2021 Scientific Article in Diabetes Care Diabetes Care 44, 2269-2276 (2021)
Islet autoimmunity and HLA markers of presymptomatic and clinical type 1 diabetes: Joint analyses of prospective cohort studies in Finland, Germany, Sweden, and the U.S.
2021 Scientific Article in Appetite Appetite 166:105476 (2021)
Competing influences on healthy food choices: Mindsetting versus contextual food cues.
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Resting-state functional connectivity of the human hypothalamus.
2021 Review in Nutrition Nutrition 89:111348 (2021)
Resolution of severe hepatosteatosis in a cystic fibrosis patient with multifactorial choline deficiency: A case report.
2021 Scientific Article in Communications Biology Comm. Biol. 4:826 (2021)
Deletion of the diabetes candidate gene Slc16a13 in mice attenuates diet-induced ectopic lipid accumulation and insulin resistance.
2021 Communications Biology Comm. Biol. 4:890 (2021)
Publisher Correction: Deletion of the diabetes candidate gene Slc16a13 in mice attenuates diet-induced ectopic lipid accumulation and insulin resistance.
2021 Scientific Article in Clinical and translational medicine Clin. Transl. Med. 11:e470 (2021)
Human and mouse non-targeted metabolomics identify 1,5-anhydroglucitol as SGLT2-dependent glycemic marker.
2021 Scientific Article in Advanced science Adv. Sci. 8:e2101281 (2021)
Reduced acrolein detoxification in akr1a1a zebrafish mutants causes impaired insulin receptor signaling and microvascular alterations.
2021 Editorial in Frontiers in Endocrinology Front. Endocrin. 12:722790 (2021)
Editorial: Stem cells in endocrine tumors.
2021 Scientific Article in Biomolecules Biomolecules 11:1023 (2021)
Synthetic material abdominal swabs reduce activation of platelets and leukocytes compared to cotton materials.
2021 Scientific Article in Molecular Metabolism Mol. Metab. 53, 101295 (2021)
Correlation guided Network Integration (CoNI) reveals novel genes affecting hepatic metabolism.
2021 Scientific Article in Cancers Cancers 13:3097 (2021)
Gender-specific efficacy revealed by head-to-head comparison of pasireotide and octreotide in a representative in vivo model of nonfunctioning pituitary tumors.
2021 Editorial in Molecular Metabolism Mol. Metab. 50:101274 (2021)
NAFLD - A rising metabolic disease.
2021 Scientific Article in Nature biomedical engineering Nat. Bio. Eng. 5, 897-913 (2021)
Single-cell-resolved differentiation of human induced pluripotent stem cells into pancreatic duct-like organoids on a microwell chip.
2021 Scientific Article in Nature biomedical engineering Nat. Bio. Eng. 5, 1246-1260 (2021)
T cells armed with C-X-C chemokine receptor type 6 enhance adoptive cell therapy for pancreatic tumours.
2021 Scientific Article in EMBO Reports EMBO Rep.:e52553 (2021)
Residual pluripotency is required for inductive germ cell segregation.
2021 Scientific Article in Cancers Cancers 13:2843 (2021)
Elevated expression of the rage variant-v in sclc mitigates the effect of chemotherapeutic drugs.
2021 Scientific Article in Genome Medicine Genome Med. 13:105 (2021)
Circulating bacterial signature is linked to metabolic disease and shifts with metabolic alleviation after bariatric surgery.
2021 Scientific Article in Pediatric obesity Pediatr. Obes. 16:e12822 (2021)
Elevated transaminases potentiate the risk for emerging dysglycemia in children with overweight and obesity.
2021 Editorial in Journal of Magnetic Resonance Imaging J. Magn. Reson. Imaging 55, 541-542 (2021)
Editorial for "Concentration of gallbladder phosphatidylcholine in cholangiopathies: A 31 P MR spectroscopy pilot study".
2021 Scientific Article in Non-coding RNA Non-coding RNA 7:32 (2021)
Changes of the tRNA modification pattern during the development of Dictyostelium discoideum.
2021 Scientific Article in Nature Communications Nat. Commun. 12:3482 (2021)
Cellular and physiological circadian mechanisms drive diurnal cell proliferation and expansion of white adipose tissue.
2021 Scientific Article in Molecular Metabolism Mol. Metab. 53:101262 (2021)
Hemostatic alterations linked to body fat distribution, fatty liver and insulin resistance.
Methods in Molecular Biology In: Mitochondrial Medicine. 2021. 69-89 (Methods Mol. Biol. ; 2277)
Drug discovery assay to identify modulators of the mitochondrial Ca2+ uniporter.
2021 Scientific Article in American Journal of Human Genetics, The Am. J. Hum. Genet. 108, 1190-1203 (2021)
Functional annotation of the 2q35 breast cancer risk locus implicates a structural variant in influencing activity of a long-range enhancer element.
2021 Scientific Article in Diabetes Care Diabetes Care 44, 1992-1999 (2021)
Epigenome-wide association study reveals methylation loci associated with offspring gestational diabetes mellitus exposure and maternal methylome.
2021 Review in Analytical and Bioanalytical Chemistry Anal. Bioanal. Chem. 413, 5567-5585 (2021)
From bedside to bench—practical considerations to avoid pre-analytical pitfalls and assess sample quality for high-resolution metabolomics and lipidomics analyses of body fluids.
2021 Scientific Article in Methods and Protocols Methods Protoc. 4:633909 (2021)
Development of an optimized clearing protocol to examine adipocyte subpopulations in white adipose tissue.
2021 Review in Advanced Therapeutics Adv. Therap. 4:2100040 (2021)
Engineering gene therapy: Advances and barriers.
2021 Scientific Article in Nature Cell Biology Nat. Cell Biol. 23, 692-703 (2021)
Epithelial cell plasticity drives endoderm formation during gastrulation.
2021 Review in Clinical Kidney Journal Clin. Kidney J. 14, 1691-1693 (2021)
Successful long-term management of recurrent focalsegmental glomerulosclerosis after kidneytransplantation with costimulation blockade.
2021 Scientific Article in NeuroImage - a Journal of Brain Function Neuroimage 237:118207 (2021)
Predictors of real-time fMRI neurofeedback performance and improvement – A machine learning mega-analysis.
2021 Scientific Article in Journal of Clinical Medicine J. Clin. Med. 10:1982 (2021)
Comparison of premixed human insulin 30/70 to biphasic aspart 30 in well-controlled patients with type 2 diabetes using continuous glucose monitoring.
2021 Scientific Article in Cellular Signalling Cell. Signal. 84:110037 (2021)
Multifaceted control of mRNA translation machinery in cancer.
2021 Scientific Article in Cell Death & Disease Cell Death Dis. 12:516 (2021)
Let-7f miRNA regulates SDF-1α- and hypoxia-promoted migration of mesenchymal stem cells and attenuates mammary tumor growth upon exosomal release.
2021 Scientific Article in Developmental Cognitive Neuroscience Dev. Cogn. Neurosci . 49:100964 (2021)
Magnetoencephalographic signatures of conscious processing before birth.
2021 Scientific Article in Nature Communications Nat. Commun. 12:2911 (2021)
A BAFF/APRIL axis regulates obesogenic diet-driven weight gain.
2021 Nature Nature 593:E14 (2021)
Author Correction: Auto-aggressive CXCR6+ CD8 T cells cause liver immune pathology in NASH.
2021 Scientific Article in eLife eLife 10:e63294 (2021)
Introduction to the EQIPD quality system.
2021 Scientific Article in Developmental Cell Dev. Cell 56, 1727-1741.e7 (2021)
RANK links senescence to stemness in the mammary epithelia, delaying tumor onset but increasing tumor aggressiveness.
2021 Review in Best Practice and Research Clinical Endocrinology and Metabolism Best Pract. Res. Clin. Endocrinol. Metab. 35:101546 (2021)
Exposure to endocrine-disrupting compounds such as phthalates and bisphenol A is associated with an increased risk for obesity.
2021 Scientific Article in STAR Protocols STAR Protoc. 2:100609 (2021)
Protocol for using heterologous spike-ins to normalize for technical variation in chromatin immunoprecipitation.
2021 Scientific Article in Communications Biology Comm. Biol. 4:666 (2021)
Aberrant activity of mitochondrial NCLX is linked to impaired synaptic transmission and is associated with mental retardation.
2021 Scientific Article in Nature Communications Nat. Commun. 12:2876 (2021)
NBR1 is a critical step in the repression of thermogenesis of p62-deficient adipocytes through PPARγ.
2021 Communications Biology Comm. Biol. 4:755 (2021)
Author Correction: Aberrant activity of mitochondrial NCLX is linked to impaired synaptic transmission and is associated with mental retardation (Communications Biology, (2021), 4, 1, (666), 10.1038/s42003-021-02114-0).
2021 Scientific Article in Advanced science Adv. Sci. 8:2100626 (2021)
Functional genomic screening during somatic cell reprogramming identifies DKK3 as a roadblock of organ regeneration.
2021 Scientific Article in BMC Genomics BMC Genomics 22:339 (2021)
Disentangling the aging gene expression network of termite queens.
2021 Scientific Article in International Journal of Molecular Sciences Int. J. Mol. Sci. 22:4998 (2021)
Is LRP2 involved in leptin transport over the blood-brain barrier and development of obesity?
2021 Scientific Article in Diabetes Aktuell Diabetes akt. 19, 82-85 (2021)
Folgeerkrankungen des Diabetes mellitus.
2021 Scientific Article in Diabetes Aktuell Diabetes akt. 19, 67-70 (2021)
Diabetes und nicht-alkoholische Fettleber-Erkrankungen.
2021 Scientific Article in Diabetes Aktuell Diabetes akt. 19, 72-75 (2021)
Insulinwirkung und -resistenz im Gehirn.
2021 Scientific Article in Diabetes Aktuell Diabetes akt. 19, 57-60 (2021)
Prävention des Typ-2-Diabetes.
2021 Scientific Article in Diabetes, Obesity and Metabolism Diabetes Obes. Metab. 23, 1868–1878 (2021)
Distribution patterns of intramyocellular and extramyocellular fat by magnetic resonance imaging in subjects with diabetes, prediabetes and normoglycaemic controls.
2021 Scientific Article in Diabetes Aktuell Diabetes akt. 19, 86-89 (2021)
Schutz und Regeneration der Betazellen.
2021 Scientific Article in Diabetologia Diabetologia 64, 1850-1865 (2021)
HAND2 is a novel obesity-linked adipogenic transcription factor regulated by glucocorticoid signalling.
2021 Scientific Article in Nature Communications Nat. Commun. 12:2999 (2021)
Orphan GPR116 mediates the insulin sensitizing effects of the hepatokine FNDC4 in adipose tissue.
2021 Letter to the Editor in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 16, 194-195 (2021)
Kommentar.
2021Vortrag: SSIB 2021, 12-15 July 2021, Online. (2021)
The effect of hunger state on hypothalamus functional connectivity in response to food cues.
2021Vortrag: SSIB 2021, 12-15 July 2021, Online. (2021)
Sex and obesity differentially influence central insulin action to food cues.
2021Vortrag: EASD 2021, 27 September-01 October 2021, Online. (2021)
Effect of a hypercaloric diet on brain insulin sensitivity and liver fat in normal-weight men.
2021 Scientific Article in Molecular Nutrition and Food Research Mol. Nutr. Food Res. 65:2000991 (2021)
Effects of insoluble cereal fibre on body fat distribution in the optimal fibre trial (OptiFiT).
2021 Review in International Journal of Molecular Sciences Int. J. Mol. Sci. 22:6176 (2021)
Hypothalamic astrocytes as a specialized and responsive cell population in obesity.
2021 Scientific Article in Diabetes Aktuell Diabetes akt. 19, 62-65 (2021)
Einfluss von Genetik und Epigenetik auf die Entstehung von Diabetes.
2021 Scientific Article in Liver International Liver Int. 41, 2101-2111 (2021)
Effects of lifestyle interventions on epigenetic signatures of liver fat: CENTRAL randomized controlled trial.
2021 Scientific Article in Cell Metabolism Cell Metab. 33, 1155-1170.e10 (2021)
Obesity-associated hyperleptinemia alters the gliovascular interface of the hypothalamus to promote hypertension.
2021 Review in Diabetes Diabetes 70, 1038-1050 (2021)
Altered β-cell prohormone processing and secretion in type 1 diabetes.
2021 Review in Frontiers in Immunology Front. Immunol. 12:667989 (2021)
Neoepitopes in type 1 diabetes: Etiological insights, biomarkers and therapeutic targets.
2021 Scientific Article in Frontiers in Immunology Front. Immunol. 12:656451 (2021)
Potential mimicry of viral and pancreatic β cell antigens through non-spliced and cis-spliced zwitter epitope candidates in type 1 diabetes.
2021 Scientific Article in JAMA network open JAMA net. open 4:e218505 (2021)
An empirically derived definition of metabolically healthy obesity based on risk of cardiovascular and total mortality.
2021 Scientific Article in Scientific Reports Sci. Rep. 11:8843 (2021)
Liver fat scores do not reflect interventional changes in liver fat content induced by high-protein diets.
2021 Scientific Article in Brain, Behavior and Immunity Brain Behav. Immun. 95, 429-443 (2021)
Type I interferon mediated induction of somatostatin leads to suppression of ghrelin and appetite thereby promoting viral immunity in mice.
2021 Scientific Article in Adipocyte Adipocyte 10, 216-231 (2021)
Cleavage of the vaspin N-terminus releases cell-penetrating peptides that affect early stages of adipogenesis and inhibit lipolysis in mature adipocytes.
2021 Scientific Article in Molecular Metabolism Mol. Metab. 51:101235 (2021)
Iron aggravates hepatic insulin resistance in the absence of inflammation in a novel db/db mouse model with iron overload.
2021 Scientific Article in American Journal of Clinical Nutrition Am. J. Clin. Nutr. 114, 134-142 (2021)
Associations of breastfeeding with childhood autoimmunity, allergies, and overweight: The Environmental Determinants of Diabetes in the Young (TEDDY) study.
2021 Scientific Article in Food and Chemical Toxicology Food Chem. Toxicol. 152:112216 (2021)
Bisphenol F and bisphenol S promote lipid accumulation and adipogenesis in human adipose-derived stem cells.
2021 Nature Cell Biology Nat. Cell Biol. 23, 566-576 (2021)
Author Correction: Non-canonical Wnt/PCP signalling regulates intestinal stem cell lineage priming towards enteroendocrine and Paneth cell fates.
2021 Scientific Article in Photoacoustics Photoacoustics 22:100263 (2021)
Croconaine-based nanoparticles enable efficient optoacoustic imaging of murine brain tumors.
2021 Review in Diabetologie, Die Diabetologie 17, 538–548 (2021)
Gestationsdiabetes mellitus (GDM), Diagnostik, Therapie und Nachsorge.Praxisempfehlung – Kurzfassung der S3-Leitlinie (AWMF-Registernummer: 057-008).
2021 Review in Consciousness and cognition Conscious. Cogn. 91:103117 (2021)
The first prior: From co-embodiment to co-homeostasis in early life.
2021 Scientific Article in Science Advances Sci. Adv. 7:eabg6424 (2021)
Disruption of paternal circadian rhythm affects metabolic health in male offspring via nongerm cell factors.
2021 Scientific Article in Mammalian Genome Mamm. Genome 32, 332-349 (2021)
A comprehensive phenotypic characterization of a whole-body Wdr45 knock-out mouse.
2021 Letter to the Editor in Med (N Y) Med. 2, 571-572 (2021)
A public health antibody screening indicates a marked increase of SARS-CoV-2 exposure rate in children during the second wave.
2021 Review in Diabetologia Diabetologia 64, 1461-1479 (2021)
Liver-targeting drugs and their effect on blood glucose and hepatic lipids.
2021 Scientific Article in Journal of Neuroscience J. Neurosci. 41, 4212-4222 (2021)
Cell-type specific dynamics of calcium activity in cortical circuits over the course of slow wave sleep and rapid eye movement sleep.
2021 Scientific Article in Gastroenterology Gastroenterology 161, 910-923.e19 (2021)
The colorectal cancer lipidome - identification of a robust tumor-specific lipid species signature.
2021 Scientific Article in FASEB Journal FASEB J. 35:e21572 (2021)
Fibroblast growth factor induced Ucp1 expression in preadipocytes requires PGE2 biosynthesis and glycolytic flux.
2021 Scientific Article in Biomedicines Biomedicines 9:345 (2021)
The effect of FGF21 and its genetic variants on food and drug cravings, adipokines and metabolic traits.
2021 Scientific Article in Comprehensive Physiology Compr. Physiol. 11, 1759-1783 (2021)
Glucagon's metabolic action in health and disease.
2021 Scientific Article in Science Translational Medicine Sci. Transl. Med. 13:eabd5666 (2021)
Transcriptional networks in at-risk individuals identify signatures of type 1 diabetes progression.
2021 Review in Molecular and Cellular Endocrinology Mol. Cell. Endocrinol. 531:111312 (2021)
Retinol-binding protein 4 in obesity and metabolic dysfunctions.
2021 Scientific Article in Thrombosis and Haemostasis Thromb. Haemost. 121, 1464-1475 (2021)
Methylglyoxal drives a distinct, nonclassical macrophage activation status.
2021 Scientific Article in Journal of Biological Chemistry, The J. Biol. Chem. 296:100611 (2021)
Chemokine-like MDL proteins modulate flowering time and innate immunity in plants.
2021 Scientific Article in Breast Cancer Research Breast Cancer Res. 23:42 (2021)
RANK signaling increases after anti-HER2 therapy contributing to the emergence of resistance in HER2-positive breast cancer.
2021 Scientific Article in ACS infectious diseases ACS Infect. Dis. 7, 1596-1606 (2021)
Multiplexed serum antibody screening platform using virus extracts from endemic Coronaviridae and SARS-CoV-2.
2021 Scientific Article in EMBO Journal, The EMBO J., e106777 (2021)
PRMT1 promotes the tumor suppressor function of p14ARF and is indicative for pancreatic cancer prognosis.
2021 Scientific Article in Cell Stem Cell Cell Stem Cell 28, 1566-1581.e8 (2021)
Activation of HERV-K(HML-2) disrupts cortical patterning and neuronal differentiation by increasing NTRK3.
2021 Scientific Article in Sleep Sleep 44:zsab056 (2021)
Occipital sleep spindles predict sequence learning in a visuo-motor task.
2021 Scientific Article in Nature Nature 592, 444-449 (2021)
Auto-aggressive CXCR6+ CD8 T cells cause liver immune pathology in NASH.
2021 Scientific Article in Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet. 129, 1, S9-S19 (2021)
Gestational diabetes mellitus (GDM), diagnostics, therapy and follow-up care. Practice recommendation - Summary of the S3 guideline (AWMF register number: 057–008).
2021 Scientific Article in Diabetologia Diabetologia 64, 1604-1612 (2021)
Maternal food consumption during late pregnancy and offspring risk of islet autoimmunity and type 1 diabetes.
2021 Review in Diabetologie, Die Diabetologie 17, 448–451 (2021)
Diabetes mellitus and the heart.
2021 Scientific Article in Diabetologia Diabetologia 64, 1358–1374 (2021)
The hepatokine fetuin-A disrupts functional maturation of pancreatic beta cells.
2021 Scientific Article in Journal of Molecular and Cellular Cardiology J. Mol. Cell. Cardiol. 156, 45-56 (2021)
Creld1 regulates myocardial development and function.
2021 Review in Frontiers in Endocrinology Front. Endocrin. 12:616506 (2021)
Impaired intestinal barrier and tissue bacteria: Pathomechanisms for metabolic diseases.
2021 Scientific Article in Frontiers in Neuroscience Front. Neurosci. 15:642589 (2021)
Diffusion tensor imaging of the sciatic nerve as a surrogate marker for nerve functionality of the upper and lower limb in patients with diabetes and prediabetes.
2021 Scientific Article in Diabetologie, Die Diabetologie 17, 307–310 (2021)
Diabetes and fatty liver.
2021 Scientific Article in Diabetologie, Die Diabetologie 17, 293–298 (2021)
Lipidtherapie bei Patienten mit Diabetes mellitus: Eine gemeinsame Stellungnahme der Kommission Fettstoffwechsel sowie der AG Herz und Diabetes der Deutschen Diabetes Gesellschaft (DDG), der Sektion Diabetologie und Stoffwechsel der Deutschen Gesellschaft für Endokrinologie (DGE), der AG Herz und Diabetes der Deutschen Gesellschaft für Kardiologie (DGK) und der gemeinsamen AG Herz – Hormone – Diabetes der DGK, DGE und DDG.
2021 Scientific Article in Biomedicines Biomedicines 9:277 (2021)
Interaction of full-length glycosylphosphatidylinositol-anchored proteins with serum proteins and their translocation to cells in vitro depend on the (Pre-)diabetic state in rats and humans.
2021 Scientific Article in Journal of Biological Chemistry, The J. Biol. Chem. 296:100361 (2021)
Disruption of the integrin-linked kinase (ILK) pseudokinase domain affects kidney development in mice.
München, Technische Universität, Fakultät Wissenschaftszentrum Weihenstephan, Diss., 2021, 111 S.
The role of TGFβ1 and microRNAs in skeletal muscle cell metabolism and differentiation.
2021 Scientific Article in Kidney International Kidney Int. 99, 1031-1032 (2021)
The Case | A 74-year-old liver transplant recipient with nephrotic-range proteinuria.
2021 Review in Journal of Neuroendocrinology J. Neuroendocrinol. 33:e12953 (2021)
Insulin action on astrocytes: From energy homeostasis to behaviour.
2021 Scientific Article in Advanced healthcare materials Adv. Healthc. Mater. 10:e2002115 (2021)
Facile synthesis of a croconaine-based nanoformulation for optoacoustic imaging and photothermal therapy.
2021 Scientific Article in Nature Communications Nat. Commun. 12:1588 (2021)
Asc-1 regulates white versus beige adipocyte fate in a subcutaneous stromal cell population.
2021 Scientific Article in Pediatric Diabetes Pediatr. Diabetes 22, 717-728 (2021)
Parental monitoring for type 1 diabetes in genetically at-risk young children: The TEDDY study.
2021 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 106, 1576-1584 (2021)
Low-density lipoprotein cholesterol is associated with insulin secretion.
2021 Scientific Article in Biology of Reproduction Biol. Reprod. 104, 1249-1261 (2021)
Anatomical and cellular heterogeneity in the mouse oviduct- its potential roles in reproduction and preimplantation development.
2021 Nature Nature 592:E1 (2021)
Author Correction: Inceptor counteracts insulin signalling in β-cells to control glycaemia.
2021 Review in International Journal of Molecular Sciences Int. J. Mol. Sci. 22:2756 (2021)
Omics approaches in adipose tissue and skeletal muscle addressing the role of extracellular matrix in obesity and metabolic dysfunction.
2021 Scientific Article in Nature Communications Nat. Commun. 12:1041 (2021)
Pharmacological but not physiological GDF15 suppresses feeding and the motivation to exercise.
2021 Scientific Article in Molecular Metabolism Mol. Metab. 49:101188 (2021)
CD81 marks immature and dedifferentiated pancreatic β-cells.
2021 Scientific Article in Endocrine-Related Cancer Endocr. Relat. Cancer 28, 213-224 (2021)
Transcriptomic landscape of radiation-induced murine thyroid proliferative lesions.
2021 Other: Opinion in Hormone and Metabolic Research Horm. Metab. Res. 53, 204-206 (2021)
The transCampus metabolic training programme explores the link of SARS-CoV-2 virus to metabolic disease.
2021 Other: Opinion in Nature metabolism Nat. Metab. 3, 289-292 (2021)
Consequences of the COVID-19 pandemic for patients with metabolic diseases.
2021 Review in International Journal of Molecular Sciences Int. J. Mol. Sci. 22:4475 (2021)
Leptin receptor compound heterozygosity in humans and animal models.
2021 Scientific Article in International Journal of Molecular Sciences Int. J. Mol. Sci. 22:4353 (2021)
Effects of whole-body adenylyl cyclase 5 (Adcy5) deficiency on systemic insulin sensitivity and adipose tissue.
2021 Review in Antioxidants Antioxidants 10:622 (2021)
Contribution of adipose tissue oxidative stress to obesity-associated diabetes risk and ethnic differences: Focus on women of African ancestry.
2021 Scientific Article in NeuroImage: Clinical Neuroimage: Clin. 30:102679 (2021)
Diminished prefrontal cortex activation in patients with binge eating disorder associates with trait impulsivity and improves after impulsivity-focused treatment based on a randomized controlled IMPULS trial.
2021 Scientific Article in American Journal of Physiology - Cell Physiology Am. J. Physiol.-Cell Physiol. 320, C1000-C1012 (2021)
Pancreatic fat cells of humans with type 2 diabetes display reduced adipogenic and lipolytic activity.
2021 Review in Nature Reviews - Endocrinology Nat. Rev. Endocrinol. 17, 276-295 (2021)
Lipid and glucose metabolism in white adipocytes: Pathways, dysfunction and therapeutics.
2021 Scientific Article in Science Advances Sci. Adv. 7:eabd6527 (2021)
Islet expression of type I interferon response sensors is associated with immune infiltration and viral infection in type 1 diabetes.
2021 Scientific Article in Diabetes Care Diabetes Care 44, 2260-2268 (2021)
An age-related exponential decline in the risk of multiple islet autoantibody seroconversion during childhood.
2021 Scientific Article in ESC heart failure ESC Heart Fail. 8, 938-942 (2021)
Low-fat hypocaloric diet reduces neprilysin in overweight and obese human subjects.
2021 Scientific Article in Acta Physiologica Acta Physiol. 232:e13640 (2021)
Zymogen-locked mutant prostasin (Prss8) leads to incomplete proteolytic activation of the epithelial sodium channel (ENaC) and severely compromises triamterene tolerance in mice.
2021 Review in Nature metabolism Nat. Metab. 3, 299-308 (2021)
POMC neuronal heterogeneity in energy balance and beyond: An integrated view.
2021 Scientific Article in Clinical Epigenetics Clin. Epigenet. 13:48 (2021)
Lifestyle weight-loss intervention may attenuate methylation aging: The CENTRAL MRI randomized controlled trial.
2021 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 106, E3198-E3207 (2021)
Lifestyle intervention improves prothrombotic coagulation profile in individuals at high-risk for type 2 diabetes.
2021 Scientific Article in BMC Pediatrics BMC Pediatr. 21:111 (2021)
Body composition in term offspring after maternal gestational diabetes does not predict postnatal hypoglycemia.
2021 Nature Nature 589, E6 (2021)
Publisher Correction: Inhibition of LTβR signalling activates WNT-induced regeneration in lung (Nature, (2020), 588, 7836, (151-156), 10.1038/s41586-020-2882-8).
2021 Nature Nature 592:E8 (2021)
Publisher Correction: LifeTime and improving European healthcare through cell-based interceptive medicine (Nature, (2020), 587, 7834, (377-386), 10.1038/s41586-020-2715-9).
2021 Scientific Article in European Journal of Nutrition Eur. J. Nutr. 60, 3499-3504 (2021)
Similar dietary regulation of IGF-1- and IGF-binding proteins by animal and plant protein in subjects with type 2 diabetes.
2021 Scientific Article in Nature Communications Nat. Commun. 12:1152 (2021)
Exploring beyond clinical routine SARS-CoV-2 serology using MultiCoV-Ab to evaluate endemic coronavirus cross-reactivity.
2021 Scientific Article in eLife eLife 10:e62161 (2021)
Human ORC/MCM density is low in active genes and correlates with replication time but does not delimit initiation zones.
2021 Scientific Article in Ethology Ecology and Evolution Ethol. Ecol. Evol. 33, 248-272 (2021)
Cryptochrome 1a localisation in light- and dark-adapted retinae of several migratory and non-migratory bird species: no signs of light-dependent activation.
2021 Scientific Article in Neuroendocrinology Neuroendocrinology 111, 263-272 (2021)
Lipid droplets accumulate in the hypothalamus of mice and humans with and without metabolic diseases.
2021 Letter to the Editor in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 16, 105-105 (2021)
Kommentar.
2021 Nature Communications Nat. Commun. 12:1804 (2021)
Author Correction: Endogenous FGF21-signaling controls paradoxical obesity resistance of UCP1-deficient mice (Nature Communications, (2020), 11, 1, (624), 10.1038/s41467-019-14069-2).
2021 Scientific Article in BMJ Open Ophthalmology BMJ Open Ophthalmol. 6:e000688 (2021)
Testing for SARS-CoV-2 seroprevalence: Experiences of a tertiary eye centre.
2021 Scientific Article in Frontiers in Immunology Front. Immunol. 12:626308 (2021)
Integrin activation enables sensitive detection of functional CD4+ and CD8+ T cells: Application to characterize SARS-CoV-2 immunity.
2021 Scientific Article in Metabolism: clinical and experimental Metabolism 119:154776 (2021)
Determinants of hepatic insulin clearance - results from a Mendelian Randomization study.
2021 Review in Diabetologie, Die Diabetologie 17, 382–390 (2021)
Erhöhte Darmpermeabilität: Pathomechanismus für metabolische Erkrankungen?
2021 Scientific Article in Cell calcium Cell Calcium 95:102364 (2021)
Towards a systems-level understanding of mitochondrial biology.
2021 Scientific Article in Biomedicines Biomedicines 9:131 (2021)
Role of kallikrein 7 in body weight and fat mass regulation.
2021 Nature Communications Nat. Commun. 12:989 (2021)
Publisher Correction: Loss of POMC-mediated antinociception contributes to painful diabetic neuropathy.
2021 Scientific Article in Scientific Reports Sci. Rep. 11:3627 (2021)
Children's erythrocyte fatty acids are associated with the risk of islet autoimmunity.
2021 Scientific Article in Nutrients Nutrients 13:556 (2021)
No effect of lifestyle intervention during third trimester on brain programming in fetuses of mothers with gestational diabetes.
2021 Scientific Article in Molecules Molecules 26:1403 (2021)
Tart cherry juice and seeds affect pro-inflammatory markers in visceral adipose tissue of high-fat diet obese rats.
2021 Scientific Article in International Journal of Molecular Sciences Int. J. Mol. Sci. 22:3434 (2021)
Generation of a novel nkx6-1 venus fusion reporter mouse line.
2021 Scientific Article in PLoS ONE PLoS ONE 16:e0248594 (2021)
Unbiased analysis of obesity related, fat depot specific changes of adipocyte volumes and numbers using light sheet fluorescence microscopy.
2021 Review in CNS drugs. CNS Drugs 35, 21-37 (2021)
Intranasal insulin for Alzheimer's disease.
2021 Scientific Article in Clinical Pharmacology & Therapeutics : CPT Clin. Pharmacol. Ther. 110, 149-158 (2021)
Genetic variation in sodium-glucose cotransporter 2 and heart failure.
2021 Review in International Journal of Molecular Sciences Int. J. Mol. Sci. 22:1500 (2021)
Does C-C motif chemokine ligand 2 (CCL2) link obesity to a pro-inflammatory state?
2021 Scientific Article in Cell Reports Cell Rep. 34:108742 (2021)
The glucocorticoid receptor recruits the COMPASS complex to regulate inflammatory transcription at macrophage enhancers.
2021 Review in Trends in Cell Biology Trends Cell Biol. 31, 345-358 (2021)
Lipid droplet contact sites in health and disease.
2021 Review in Nature Genetics Nat. Genet. 53, 416-419 (2021)
A resource of targeted mutant mouse lines for 5,061 genes.
2021 Scientific Article in Physiological research Physiol. Res. 70, 227-236 (2021)
Analysis of the sex-specific variability of blood parameters in C3H inbred mice by using data from a long-term, high-throughput project.
2021 Scientific Article in International Journal of Molecular Sciences Int. J. Mol. Sci. 22:1571 (2021)
Treatment-induced neuropathy in diabetes (Tind)—developing a disease model in type 1 diabetic rats.
2021 Scientific Article in Endocrinology Endocrinology 162:bqab017 (2021)
Diabetes type 1 negatively influences Leydig cell function in rats which is partially reversible by insulin treatment.
2021 Scientific Article in Molecular Metabolism Mol. Metab. 49:101181 (2021)
Spatiotemporal GLP-1 and GIPR receptor signaling and trafficking/recycling dynamics induced by selected receptor mono- and dual-agonists.
2021 Scientific Article in Journal of Clinical Medicine J. Clin. Med. 10:411 (2021)
Detection and characterization of phosphorylation, glycosylation, and fatty acid bound to fetuin A in human blood.
2021 Scientific Article in JCI insight JCI insight 6:e136083 (2021)
The longevity gene mIndy (I’m Not Dead, Yet) affects blood pressure through sympathoadrenal mechanisms.
2021 Letter to the Editor in Molecular Metabolism Mol. Metab. 45:101159 (2021)
Divide et impera: How mitochondrial fission in astrocytes rules obesity.
2021 Scientific Article in Nature metabolism Nat. Metab. 3, 149-165 (2021)
SARS-CoV-2 infects and replicates in cells of the human endocrine and exocrine pancreas.
2021 Scientific Article in Nature Communications Nat. Commun. 12:674 (2021)
PDX1LOW MAFALOW β-cells contribute to islet function and insulin release.
2021 Scientific Article in Diabetologia Diabetologia 64, 1079-1092 (2021)
Oral insulin immunotherapy in children at risk for type 1 diabetes in a randomised controlled trial.
2021 Review in Diabetologie, Die Diabetologie 17, 141–148 (2021)
Inflammation: Zwischen Adipositas, Diabetes und Sport.
2021 Scientific Article in Diabetologie, Die Diabetologie 17, 26-31 (2021)
Neue Subtypen bei Prädiabetes.
2021 Scientific Article in Nutrients Nutrients 13:395 (2021)
Vitamin B12 supplementation in diabetic neuropathy: A 1-year, randomized, double-blind, placebo-controlled trial.
2021 Review in Journal of Neuroendocrinology J. Neuroendocrinol. 33:e12934 (2021)
Intranasal insulin.
2021 Scientific Article in Frontiers in Psychology Front. Psychol. 11:607070 (2021)
Vast amounts of encoded items nullify but do not reverse the effect of sleep on declarative memory.
2021 Scientific Article in Thrombosis and Haemostasis Thromb. Haemost. 121, 782-791 (2021)
Specific point-of-care testing of coagulation in patients treated with dabigatran.
2021 Scientific Article in Journal of Chromatography J. Chromatogr. B 1165:122553 (2021)
Determination of 3-iodothyronamine (3-T1AM) in mouse liver using liquid chromatography-tandem mass spectrometry.
2021 Scientific Article in Diabetes Diabetes 70, 303-312 (2021)
Emerging role of bone morphogenetic protein 4 in metabolic disorders.
2021 Scientific Article in International Journal of Obesity Int. J. Obes. 45, 840–849 (2021)
Reduced metabolic efficiency in sedentary eucaloric conditions predicts greater weight regain in adults with obesity following sustained weight loss.
2021 Review in Molecular Metabolism Mol. Metab. 47:101169 (2021)
A guide to understanding endoplasmic reticulum stress in metabolic disorders.
2021 Scientific Article in Microvascular Research Microvasc. Res. 135:104131 (2021)
Leptin promotes adipocytes survival in non-vascularized fat grafting via perfusion increase.
2021 Scientific Article in Molecular Metabolism Mol. Metab. 45:101147 (2021)
Active integrins regulate white adipose tissue insulin sensitivity and brown fat thermogenesis.
2021 Scientific Article in Cell Reports Cell Rep. 34:108624 (2021)
Endogenous fatty acid synthesis drives brown adipose tissue involution.
2021 Scientific Article in Monatsschrift Kinderheilkunde Mon.schr. Kinderheilkd. 169, 451–460 (2021)
Kann die Ketoacidose bei pädiatrischen Patienten mit Manifestation eines Diabetes mellitus Typ 1 vermieden werden? Lehren aus der COVID-19-Pandemie.
2021 Scientific Article in Cancers Cancers 13:126 (2021)
Mutation of the cell cycle regulator p27kip1 drives pseudohypoxic pheochromocytoma development.
2021 Scientific Article in PLoS ONE PLoS ONE 16:e0242830 (2021)
Balancing the brain of offenders with psychopathy? Resting state EEG and electrodermal activity after a pilot study of brain self-regulation training.
Methods in Molecular Biology In: Proteomic Profiling. 2021. 433-442 (Methods Mol. Biol. ; 2261)
Methods for proteomics-based analysis of the human muscle secretome using an in vitro exercise model.
2021 Scientific Article in Nature Nature 590, 326–331 (2021)
Inceptor counteracts insulin signalling in β-cells to control glycaemia.
2021 Scientific Article in FASEB Journal FASEB J. 35:e21302 (2021)
Systemic Jak1 activation provokes hepatic inflammation and imbalanced FGF23 production and cleavage.
2021 Scientific Article in Experimental Eye Research Exp. Eye Res. 204:108432 (2021)
Ionising radiation causes vision impairment in neonatal B6C3F1 mice.
2021 Scientific Article in Diabetologia Diabetologia 64, 591-602 (2021)
First-appearing islet autoantibodies for type 1 diabetes in young children: Maternal life events during pregnancy and the child’s genetic risk.
2021 Scientific Article in Nature metabolism Nat. Metab. 3, 394–409 (2021)
Liver alanine catabolism promotes skeletal muscle atrophy and hyperglycaemia in type 2 diabetes.
2021 Scientific Article in Frontiers in cell and developmental biology Front. Cell Dev. Biol. 9:641410 (2021)
TBL1XR1 ensures balanced neural development through NCOR complex-mediated regulation of the MAPK pathway.
2021 Scientific Article in Cell Metabolism Cell Metab. 33, 833-844.e5 (2021)
The glucose-dependent insulinotropic polypeptide (GIP) regulates body weight and food intake via CNS-GIPR signaling.
2021 Scientific Article in EMBO Molecular Medicine EMBO Mol. Med.:e12461 (2021)
Combination therapies induce cancer cell death through the integrated stress response and disturbed pyrimidine metabolism.
2021 Scientific Article in Life Science Alliance Life Sci. All. 4:e202000898 (2021)
Lipocalin 13 enhances insulin secretion but is dispensable for systemic metabolic control.
2021 Scientific Reports Sci. Rep. 11:3582 (2021)
Author Correction: Edgetic perturbation signatures represent known and novel cancer biomarkers (Scientific Reports, (2020), 10, 1, (4350), 10.1038/s41598-020-61422-3).
2021 Scientific Article in Metabolites Metabolites 11:89 (2021)
Validation of candidate phospholipid biomarkers of chronic kidney disease in hyperglycemic individuals and their organ-specific exploration in leptin receptor-deficient db/db mouse.
2021 Scientific Article in Clinical Kidney Journal Clin. Kidney J. 14, 269-276 (2021)
Urinary fetuin-A peptides as a new marker for impaired kidney function in patients with type 2 diabetes.
2021 Scientific Article in Cell Reports Cell Rep. 34:108748 (2021)
Dynamic adoption of anergy by antigen-exhausted CD4+ T cells.
2021 Scientific Article in Nucleic Acids Research Nucleic Acids Res. 49, 902-915 (2021)
A ubiquitin switch controls autocatalytic inactivation of the DNA-protein crosslink repair protease SPRTN.
2021 Scientific Article in Radiology. Artificial intelligence Radiol. Artif. Intell. 2:e200010 (2021)
Fully automated and standardized segmentation of adipose tissue compartments via deep learning in 3D whole-body MRI of epidemiological cohort studies.
2021 Review in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 16, 63-69 (2021)
Neue Klassifikation des Diabetes mellitus – Anforderungen an Labormessgrößen.
2021 Scientific Article in Nature Communications Nat. Commun. 12:426 (2021)
Loss of POMC-mediated antinociception contributes to painful diabetic neuropathy.
2021 Review in Nature Reviews - Endocrinology Nat. Rev. Endocrinol. 17, 135–149 (2021)
Global pandemics interconnected - obesity, impaired metabolic health and COVID-19.
2021 Scientific Article in Diabetes Care Diabetes Care 44, 774-780 (2021)
Durable effects of iGlarLixi up to 52 weeks in type 2 diabetes: The LixiLan-G Extension Study.
2021 Scientific Article in Nature medicine Nat. Med. 27, 49-57 (2021)
Pathophysiology-based subphenotyping of individuals at elevated risk for type 2 diabetes.
2021 Scientific Article in Nature Cell Biology Nat. Cell Biol. 23, 23-31 (2021)
Non-canonical Wnt/PCP signalling regulates intestinal stem cell lineage priming towards enteroendocrine and Paneth cell fates.
2021 Scientific Article in Nature Structural & Molecular Biology Nat. Struct. Mol. Biol. 28, 143–151 (2021)
Imbalances in the eye lens proteome are linked to cataract formation.
2021 Scientific Article in Cellular Immunology Cell. Immunol. 361:104276 (2021)
Extracellular vesicles released by myeloid-derived suppressor cells from pregnant women modulate adaptive immune responses.
2021 Scientific Article in PLoS Genetics PLoS Genet. 16:e1009190 (2021)
Mouse mutant phenotyping at scale reveals novel genes controlling bone mineral density.
2021 Scientific Article in Psychotherapeut Psychotherapeut 66, 28–34 (2021)
Stigmatisierung und Diskriminierung von Patient*innen mit Adipositas.
2021 Scientific Article in Metabolism: clinical and experimental Metabolism 116:154438 (2021)
Identification of a novel leptin receptor (LEPR) variant and proof of functional relevance directing treatment decisions in patients with morbid obesity.
2021 Review in Medical Hypotheses Med. Hypotheses 146:110474 (2021)
Long distance running – Can bioprofiling predict success in endurance athletes?
2021 Scientific Article in Diabetes Diabetes 70, 752-758 (2021)
One in ten CD8+ cells in the pancreas of living individuals with recent onset type 1 diabetes recognizes the preproinsulin epitope PPI15-24.
2021 Scientific Article in Journal of Proteome Research J. Proteome Res. 20, 1005-1014 (2021)
Metabolite triplet in serum improves the diagnostic accuracy of prediabetes and diabetes screening.
2021 Review in Trends in Pharmacological Sciences Trends Pharmacol. Sci. 42, 85-95 (2021)
Pharmacological targeting of endoplasmic reticulum stress in pancreatic beta cells.
2021 Scientific Article in Stem Cell Research Stem Cell Res. 50:102126 (2021)
Generation of a heterozygous C-peptide-mCherry reporter human iPSC line (HMGUi001-A-8).
2021 Scientific Article in Journal of Steroid Biochemistry and Molecular Biology, The J. Steroid Biochem. Mol. Biol. 206:105790 (2021)
Homology modeling meets site-directed mutagenesis: An ideal combination to elucidate the topology of 17β-HSD2.
2021 Scientific Article in Thyroid Thyroid 31, 519-527 (2021)
Effects of hyperthyroidism on adipose tissue activity and distribution in adults.
2021 Scientific Article in Diabetes Diabetes 70, 282-292 (2021)
Plasma metabolome and circulating vitamins stratified onset age of an initial islet autoantibody and progression to type 1 diabetes: The TEDDY Study.
2021 Scientific Article in Med (N Y) Med. 2, 149-163.e4 (2021)
Public health antibody screening indicates a six-fold higher SARS-CoV-2 exposure rate than reported cases in children.
2021 Scientific Article in Diabetes Diabetes 70, 91-98 (2021)
Small amounts of dietary medium-chain fatty acids protect against insulin resistance during caloric excess in humans.
2021 Scientific Article in Diabetes Diabetes 70, 616-626 (2021)
CaM kinase II-δ is required for diabetic hyperglycemia and retinopathy but not nephropathy.
2021 Editorial in Nature Reviews - Endocrinology Nat. Rev. Endocrinol. 17, 73–74 (2021)
Shortening the paths to type 1 diabetes mellitus prevention.
2021 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 106, e982-e989 (2021)
Elevated circulating glutamate associates with subclinical atherosclerosis independently of established risk markers: A cross-sectional study.
2021 Scientific Article in Life Science Alliance Life Sci. All. 4:e202000924 (2021)
Identification and characterization of distinct brown adipocyte subtypes in C57BL/6J mice.
2021 Scientific Article in International Journal of Radiation Biology Int. J. Radiat. Biol. 97, 156-169 (2021)
Dose-dependent long-term effects of a single radiation event on behaviour and glial cells.
2021 Scientific Article in Cancer Immunology, Immunotherapy Cancer Immunol. Immunother. 70, 1263-1275 (2021)
Noninvasive, longitudinal imaging-based analysis of body adipose tissue and water composition in a melanoma mouse model and in immune checkpoint inhibitor-treated metastatic melanoma patients.
2021 Scientific Article in Journal of Nutritional Biochemistry, The J. Nutr. Biochem. 87:108516 (2021)
Short-term high-fat feeding induces a reversible net decrease in synaptic AMPA receptors in the hypothalamus.
2021 Scientific Article in Electrochimica Acta Electrochim. Acta 365:137326 (2021)
Electroactive microorganisms in mouse feces.
2021 Scientific Article in Diabetes, Obesity and Metabolism Diabetes Obes. Metab. 23, 195-207 (2021)
Plasma proteome profiles treatment efficacy of incretin dual agonism in diet-induced obese female and male mice.
2021 Scientific Article in Journal of Sleep Research J. Sleep Res. 30, e13204 (2021)
Pregnant women do not display impaired memory formation across one night of sleep.
2021 Scientific Article in Journal of Proteomics J. Proteomics 230:103981 (2021)
Proteasuria in nephrotic syndrome–quantification and proteomic profiling.
2021 Scientific Article in Brain and behavior Brain Behav. 11:e01928 (2021)
Diabetes type 2 risk gene Dusp8 is associated with altered sucrose reward behavior in mice and humans.
2021 Scientific Article in European Journal of Neuroscience Eur. J. Neurosci. 53, 390-401 (2021)
Loss of the psychiatric risk factor SLC6A15 is associated with increased metabolic functions in primary hippocampal neurons.
2021 Scientific Article in Progress in Biophysics and Molecular Biology Prog. Biophys. Mol. Biol. 159, 86-104 (2021)
Transcriptional signatures regulated by TRPC1/C4-mediated Background Ca2+ entry after pressure-overload induced cardiac remodelling.
2021 Scientific Article in Reproductive Biomedicine Online Reprod. Biomed. Online 42, 217-225 (2021)
Pregnancy outcome in women with polycystic ovary syndrome in relation to second-trimester testosterone levels.
2021 Scientific Article in Fortschritte auf dem Gebiet der Röntgenstrahlen und der Bildgebenden Verfahren Rofo-Fortschr. Rontg. 193, 33-41 (2021)
Magnetic resonance imaging of diverticular disease and its association with adipose tissue compartments and constitutional risk factors in subjects from a western general population.
2021 Scientific Article in International Journal of Radiation Oncology, Biology, Physics Int. J. Radiat. Oncol. Biol. Phys. 109, 76-83 (2021)
Normal tissue response of combined temporal and spatial fractionation in proton minibeam radiation therapy.
2021 Scientific Article in Developmental psychobiology Dev. Psychobiol. 63, 5-15 (2021)
Tracking evoked responses to auditory and visual stimuli in fetuses exposed to maternal high-risk conditions.
2021 Review in NMR in Biomedicine NMR Biomed.:e4266 (2021)
Proton magnetic resonance spectroscopy in skeletal muscle: Experts' consensus recommendations.
2021 Scientific Article in Experimental and Clinical Endocrinology & Diabetes Exp. Clin. Endocrinol. Diabet. 129, 750-756 (2021)
Carotid intima-media thickness is a predictor of subclinical myocardial damage in men with type 2 diabetes mellitus.
München, Technische Universität, Fakultät für Medizin, Diss., 2020, 154 S.
Myeloid cells require the ribonuclease Regnase-3 for immune homeostasis and balanced interferon responses in vivo.
2020 Editorial in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 15, 443-446 (2020)
Epigenetic mechanisms in patients with obesity: Fine-tuning of gene activity through DNA-methylation Bertram-Award 2020-a brief overview by the Award Winner Yvonne Boettcher.
2020Vortrag: ASCB/EMBO Cell Bio Vitrual, 07.-12.12.2020, online. (2020)
Endosomal sorting complex protein Vps37a regulates hepatic glucose production via regulating glucagon receptor trafficking.
2020 Frontiers in Psychology Front. Psychol. 11:612441 (2020)
Corrigendum: Core neuropsychological measures for obesity and diabetes trials: Initial report (Front. Psychol, (2020), 11, (554127), 10.3389/fpsyg.2020.554127).
2020 Editorial in Diabetologie, Die Diabetologie 16, 627-629 (2020)
Neues aus der Diabetesforschung.
2020 Meeting abstract in Diabetologia Diabetologia 63, 1, S181-S181 (2020)
Optimal ages for screening for type 1 diabetes risk in children.
2020 Editorial in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 15, 366-366 (2020)
Do NASH-biomarkers follow weight loss in dual GIP-GLP-1-inhibition? Comment.
2020 Meeting abstract in Diabetologia Diabetologia 63, 1, S254-S255 (2020)
Comparison between in vitro differentiation of pancreatic and subcutaneous adipocytes of subjects with normal glucose tolerance.
2020 Meeting abstract in Diabetologia Diabetologia 63, 1, S14-S14 (2020)
Brain insulin sensitivity is modulated by menstrual cycle.
2020 Meeting abstract in Diabetologia Diabetologia 63, 1, S21-S22 (2020)
Oncostatin M inhibits browning of white adipose tissue via gp130 signalling.
2020 Meeting abstract in Diabetologia Diabetologia 63, 1, S384-S385 (2020)
Urinary cathepsin levels are predictive of the improvement of albuminuria and are associated with elevated excretion of free glucosepane.
2020 Meeting abstract in Diabetologia Diabetologia 63, 1, S157-S157 (2020)
Presence of markers associated with viral infections in the pancreas before and after onset of type 1 diabetes.
2020 Meeting abstract in Diabetologia Diabetologia 63, 1, S26-S27 (2020)
Long-term follow-up study of type 1 diabetes patients previously treated with IMCY-0098 or placebo in young adults with recent-onset type 1 diabetes.
2020 Meeting abstract in Diabetologia Diabetologia 63, 1, S101-S102 (2020)
Visualising heterogeneous islet autoantibody trajectories of children who develope type 1 diabetes from multi-site birth cohort studies.
2020 Meeting abstract in Diabetologia Diabetologia 63, 1, S159-S159 (2020)
A visual analytics method to explore the evolution of autoantibodies during progression to type 1 diabetes in multi-site birth cohort studies.
2020 Meeting abstract in Diabetologia Diabetologia 63, 1, S160-S160 (2020)
Heterogeneous islet autoantibody evolution trajectories in multi-site birth cohort studies.
2020 Meeting abstract in Diabetologia Diabetologia 63, 1, S211-S212 (2020)
Maternal mental state correlates with maternal insulin sensitivity and interleukin-6 levels in late pregnancy.
2020 Meeting abstract in Diabetologia Diabetologia 63, 1, S13-S14 (2020)
Empagliflozin improves insulin sensitivity of the hypothalamus in humans with prediabetes.
2020 Meeting abstract in Diabetologia Diabetologia 63, 1, S36-S37 (2020)
Evaluation of determinants of hepatic insulin clearance: a Mendelian randomisation study.
2020 Meeting abstract in Diabetologia Diabetologia 63, 1, S98-S98 (2020)
Exercise changes neuronal processing of food cues in sedentary overweight and obese adults.
2020 Meeting abstract in Diabetologia Diabetologia 63, 1, S182-S183 (2020)
Lrh1/nr5a2 conveys the anti-diabetic effects of the agonist bl001 and promotes alpha-to-beta-cell conversion in streptozotocin-treated mice.
2020 Meeting abstract in Diabetologia Diabetologia 63, 1, S258-S258 (2020)
Postprandial thermogenesis is reduced in obesity.
2020 Editorial in Journal of Neuroendocrinology J. Neuroendocrinol. 32:e12927 (2020)
Neuroendocrinology and brain imaging.
2020 Scientific Article in Eating and Weight Disorders Eat Weight Disord., DOI: 10.1007/s40519-020-01071-7 (2020)
Body appreciation and appearance evaluation in individuals with obesity compared to individuals with normal-weight: findings from a representative German population sample.
2020 Scientific Article in Obesity Obesity 28, 2266-2267 (2020)
Effects of exercise on ACE2.
2020 Scientific Article in Laryngoscope, The Laryngoscope, DOI: 10.1002/lary.29300 (2020)
Fibrin gel suspended autologous chondrocytes as cell-based material for long-term injection laryngoplasty.
2020 Scientific Article in International Journal of Molecular Sciences Int. J. Mol. Sci. 21:9647 (2020)
Intergenerational metabolomic analysis of mothers with a history of gestational diabetes mellitus and their offspring.
2020 Scientific Article in Frontiers in Immunology Front. Immunol. 11:574046 (2020)
Tribbles-1 expression and its function to control inflammatory cytokines, including interleukin-8 levels are regulated by miRNAs in macrophages and prostate cancer cells.
2020 Scientific Article in Nature metabolism Nat. Metab. 2, 1021-1024 (2020)
Autoantibody-negative insulin-dependent diabetes mellitus after SARS-CoV-2 infection: A case report.
2020 Molecular Metabolism Mol. Metab. 41:101068 (2020)
Molecular regulation of urea cycle function by the liver glucocorticoid receptor (vol 4, pg 732, 2015).
2020 Scientific Article in Redox Biology Redox Biol. 37:101723 (2020)
Elevated 4-hydroxynonenal induces hyperglycaemia via Aldh3a1 loss in zebrafish and associates with diabetes progression in humans.
2020 Scientific Article in Sleep Sleep 44:zsaa290 (2020)
How do children with autism spectrum disorder form gist memory during sleep? - A study of slow oscillation-spindle coupling.
2020 Scientific Article in Scientific Reports Sci. Rep. 10:22396 (2020)
Dapagliflozin effects on haematocrit, red blood cell count and reticulocytes in insulin-treated patients with type 2 diabetes.
2020 Scientific Article in Frontiers in Immunology Front. Immunol. 11:606338 (2020)
Specific induction of double negative B cells during protective and pathogenic immune responses.
2020 Scientific Article in Scientific Reports Sci. Rep. 10:22453 (2020)
Reduced insulin clearance is linked to subclinical atherosclerosis in individuals at risk for type 2 diabetes mellitus.
2020 Scientific Article in Acta Neuropathologica Communications Acta Neuropathol. Commun. 8:207 (2020)
Oligodendrocyte myelin glycoprotein as a novel target for pathogenic autoimmunity in the CNS.
2020 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 106, e34-e44 (2020)
Adolescent nonalcoholic fatty liver disease and type 2 diabetes in young adulthood.
2020 Other: Opinion in Kidney International Kidney Int. 98, 1393-1395 (2020)
Kidney-derived PCSK9-a new driver of hyperlipidemia in nephrotic syndrome?
2020 Scientific Article in eLife eLife 9:e56914 (2020)
Islet vascularization is regulated by primary endothelial cilia via VEGF-A-dependent signaling.
2020 Scientific Article in Kidney & Blood Pressure Research Kidney Blood Press. Res. 45, 955-968 (2020)
Overhydration measured by bioimpedance spectroscopy and urinary serine protease activity are risk factors for progression of chronic kidney disease.
2020 Scientific Article in Glia Glia, DOI: 10.1002/glia.23953 (2020)
A reporter cell system for the triggering receptor expressed on myeloid cells 2 reveals differential effects of disease-associated variants on receptor signaling and activation by antibodies against the stalk region.
2020 Scientific Article in iScience iScience 23:101763 (2020)
Regulation of guconeogenesis by aldo-keto-reductase 1a1b in zebrafish.
2020 Scientific Article in Genome Biology Genome Biol. 21:299 (2020)
Intronic tRNAs of mitochondrial origin regulate constitutive and alternative splicing.
2020 Scientific Article in Scientific Reports Sci. Rep. 10:20466 (2020)
No modulation of postprandial metabolism by transcutaneous auricular vagus nerve stimulation: A cross-over study in 15 healthy men.
2020 Scientific Article in Genome Medicine Genome Med. 12:97 (2020)
DNA methylation signature in blood mirrors successful weight-loss during lifestyle interventions: The CENTRAL trial.
2020 Scientific Article in Journal of Translational Medicine J. Transl. Med. 18:468 (2020)
Can harmonisation of outcomes bridge the translation gap for pre-clinical research? A systematic review of outcomes measured in mouse models of type 2 diabetes.
2020 Scientific Article in Nutrients Nutrients 12:3254 (2020)
Efficacy and safety of the combination of superoxide dismutase, alpha lipoic acid, Vitamin B12, and carnitine for 12 months in patients with diabetic neuropathy.
2020 Scientific Article in Metabolites Metabolites 10:472 (2020)
Mouse age matters: How age affects the murine plasma metabolome.
2020 Scientific Article in Xenotransplantation Xenotransplantation, DOI: 10.1111/xen.12664 (2020)
Growth hormone receptor knockout to reduce the size of donor pigs for preclinical xenotransplantation studies.
2020 Scientific Article in Kidney international reports Kidney Int. Rep. 5, 2114-2118 (2020)
Acute kidney allograft injury following vitamin C administration for septic shock.
2020 Review in Diabetes Therapy Diabetes Ther. 11, 2465-2476 (2020)
Insights from VERIFY: Early combination therapy provides better glycaemic durability than a stepwise approach in newly diagnosed type 2 diabetes.
2020 Scientific Article in BMJ Open Diabetes Research & Care BMJ Open Diab. Res. Care 8:e001741 (2020)
Insulin sensitivity predicts cognitive decline in individuals with prediabetes.
2020 Scientific Article in Biomedicines Biomedicines 8:507 (2020)
Increased expressions of matrix metalloproteinases (MMPs) in prostate cancer tissues of men with type 2 diabetes.
2020 Scientific Article in International Journal of Obesity Int. J. Obes. 45, 565–576 (2020)
Reduced lipolysis in lipoma phenocopies lipid accumulation in obesity.
2020 Scientific Article in Developmental Cognitive Neuroscience Dev. Cogn. Neurosci . 46:100871 (2020)
Magnetoencephalographic signatures of hierarchical rule learning in newborns.
2020 Scientific Article in Frontiers in Psychology Front. Psychol. 11:554127 (2020)
Core neuropsychological measures for obesity and diabetes trials: Initial report.
2020 Scientific Article in Frontiers in Neuroscience Front. Neurosci. 14:570744 (2020)
Diabetic polyneuropathy is associated with pathomorphological changes in human dorsal root ganglia: A study using 3T MR neurography.
2020 Review in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 15, S101-S111 (2020)
Gestationsdiabetes mellitus (GDM), Diagnostik, Therapie und Nachsorge – Praxisempfehlung – Kurzfassung der S3-Leitlinie (AWMF-Registernummer: 057-008).
2020 Review in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 15, S160-S165 (2020)
Lipidtherapie bei Patienten mit Diabetes mellitus – Eine gemeinsame Stellungnahme der Kommission Fettstoffwechsel sowie der AG Herz und Diabetes der Deutschen Diabetes Gesellschaft (DDG), der Sektion Diabetologie und Stoffwechsel der Deutschen Gesellschaft für Endokrinologie (DGE), der AG Herz und Diabetes der Deutschen Gesellschaft für Kardiologie (DGK) und der gemeinsamen AG Herz – Hormone – Diabetes der DGK, DGE und DDG.
2020 Review in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 15, S166-S169 (2020)
Diabetes mellitus and heart.
2020 Review in Diabetologie und Stoffwechsel Diabetol. Stoffwechs. 15, S156-S159 (2020)
Diabetes und Fettleber.
2020 Scientific Article in Alzheimer's & Dementia Alzheimers Dement. 6:e12097 (2020)
Novel antibody against low-n oligomers of tau protein promotes clearance of tau in cells via lysosomes.
2020 Scientific Article in Nature Nature 588, 151–156 (2020)
Inhibition of LTβR signalling activates WNT-induced regeneration in lung.
2020 Scientific Article in Journal of Neuroendocrinology J. Neuroendocrinol. 32:e12907 (2020)
Investigating obesity-associated brain inflammation using quantitative water content mapping.
2020 Scientific Article in Science Advances Sci. Adv. 6:eabc5586 (2020)
The healthy exocrine pancreas contains preproinsulin-specific CD8 T cells that attack islets in type 1 diabetes.
2020 Scientific Article in Frontiers in Immunology Front. Immunol. 11:564921 (2020)
Glutamic acid decarboxylase injection into lymph nodes: Beta cell function and immune responses in recent onset type 1 diabetes patients.
2020 Scientific Article in Medicine Medicine (Baltimore) 99:e22381 (2020)
Long-term effects of a food pattern on cardiovascular risk factors and age-related changes of muscular and cognitive function.
2020 Scientific Article in Science of the Total Environment, The Sci. Total Environ. 748:142458 (2020)
Accumulation of distinct persistent organic pollutants is associated with adipose tissue inflammation.
2020 Scientific Article in Clinical Chemistry and Laboratory Medicine Clin. Chem. Lab. Med. 59, 913-920 (2020)
Evaluation of the first immunosuppressive drug assay available on a fully automated LC-MS/MS-based clinical analyzer suggests a new era in laboratory medicine.
2020 Review in Antioxidants Antioxidants 9:939 (2020)
The glyoxalase system—new insights into an ancient metabolism.
2020 Scientific Article in Journal of Hepatology J. Hepatol. 73, 1347-1359 (2020)
Reduced mitochondrial resilience enables non-canonical induction of apoptosis after TNF receptor signaling in virus-infected hepatocytes.
2020 Scientific Article in Cell Communication and Signaling Cell Commun. Signal. 18:155 (2020)
Thrombospondin-1/CD47 signaling modulates transmembrane cation conductance, survival, and deformability of human red blood cells.
2020 Scientific Article in Journal of Cachexia, Sarcopenia and Muscle J. Cachexia Sarcopenia Muscle 11, 1459-1475 (2020)
High levels of modified ceramides are a defining feature of murine and human cancer cachexia.
2020 Scientific Article in PLoS ONE PLoS ONE 15:e0238533 (2020)
Molecular classification of the placebo effect in nausea.
2020 Scientific Article in RNA RNA 26, 1489-1506 (2020)
Validation strategies for antibodies targeting modified ribonucleotides.
2020 Scientific Article in Advanced materials Adv. Mater. 32:e2003913 (2020)
Prediction of chronic inflammation for inhaled particles: The impact of material cycling and quarantining in the lung epithelium.
2020 Scientific Article in Scientific Reports Sci. Rep. 10:18334 (2020)
Increased estrogen to androgen ratio enhances immunoglobulin levels and impairs B cell function in male mice.
2020 Scientific Article in Frontiers in cell and developmental biology Front. Cell Dev. Biol. 8:587778 (2020)
Dose-dependent and subset-specific regulation of midbrain dopaminergic neuron differentiation by LEF1-mediated WNT1/b-catenin signaling.
2020 Scientific Article in Proceedings of the National Academy of Sciences of the United States of America Proc. Natl. Acad. Sci. U.S.A. 117, 23925-23931 (2020)
Medin aggregation causes cerebrovascular dysfunction in aging wild-type mice.
2020 Scientific Article in iScience iScience 23:101516 (2020)
Progressive proteome changes in the myocardium of a pig model for Duchenne. muscular dystrophy.
2020 Scientific Article in Communications Biology Comm. Biol. 3:628 (2020)
PAX6 mutation alters circadian rhythm and beta cell function in mice without affecting glucose tolerance.
2020 Scientific Article in Molecular Nutrition and Food Research Mol. Nutr. Food Res. 64:e2000419 (2020)
Dietary rapeseed oil supplementation reduces hepatic steatosis in obese men-a randomized controlled trial.
2020 Scientific Article in Cancer Research Cancer Res. 80, 5231-5244 (2020)
Phosphorylation control of p53 DNA binding cooperativity balances tumorigensis and aging.
2020 Scientific Article in Cell Reports Cell Rep. 33:108295 (2020)
The obesity susceptibility gene TMEM18 promotes adipogenesis through direct activation of PPARG.
2020 Review in Nature Nature 587, 377–386 (2020)
LifeTime and improving European healthcare through cell-based interceptive medicine.
2020 Scientific Article in Scientific Reports Sci. Rep. 10:16497 (2020)
FFA2-, but not FFA3-agonists inhibit GSIS of human pseudoislets: A comparative study with mouse islets and rat INS-1E cells.
2020 Scientific Article in Science Advances Sci. Adv. 6:eaaz4551 (2020)
METTL6 is a tRNA m3C methyltransferase that regulates pluripotency and tumor cell growth.
2020 Review in Current opinion in pharmacology Curr. Opin. Pharmacol. 53, 101-116 (2020)
Exploiting common aspects of obesity and cancer cachexia for future therapeutic strategies.
2020 Review in Diabetologie, Die Diabetologie 16, 647–653 (2020)
Materner Metabolismus und fetale Entwicklung.
2020 Scientific Article in Molecular Metabolism Mol. Metab. 42:101062 (2020)
Histone deacetylase 5 regulates interleukin 6 secretion and insulin action in skeletal muscle.
2020 Scientific Article in International Journal of Obesity Int. J. Obes. 45, 331-336 (2020)
Circulating cell adhesion molecules in metabolically healthy obesity.
2020 Scientific Article in International Journal of Cancer Int. J. Cancer 147, 3523-3538 (2020)
miR-34a is upregulated in AIP-mutated somatotropinomas and promotes octreotide resistance.
2020 Scientific Article in American Journal of Physiology - Endocrinology and Metabolism Am. J. Physiol. Endocrinol. Metab. 319, E509-E518 (2020)
Nutritional and metabolic regulation of the metabolite dimethylguanidino valeric acid: An early marker of cardiometabolic disease.
2020 Review in Diabetologie, Die Diabetologie 16, 654-661 (2020)
Typ-1-Diabetes: Früherkennung und Ansätze zur Prävention.Update 2020.
2020 Review in Endocrinology and Metabolism Endocrinol. Metab. 35, 487–493 (2020)
Metabolically healthy and unhealthy normal weight and obesity.
2020 Scientific Article in Journal of Clinical Endocrinology & Metabolism, The J. Clin. Endocrinol. Metab. 105:dgaa571 (2020)
Response of mitochondrial respiration in adipose tissue and muscle to 8 weeks of endurance exercise in obese subjects.
2020 Scientific Article in Scientific Reports Sci. Rep. 10:15093 (2020)
Defining diagnostic cutoffs in neurological patients for serum very long chain fatty acids (VLCFA) in genetically confirmed X-Adrenoleukodystrophy.
2020 Scientific Article in International Journal of Cancer Int. J. Cancer 147, 3224-3235 (2020)
Loss of the cystine/glutamate antiporter in melanoma abrogates tumor metastasis and markedly increases survival rates of mice.
2020 Review in Diabetologie, Die Diabetologie 16, 560–565 (2020)
Fettleber und Diabetes: Pathomechanismen.
2020 Scientific Article in Nature Communications Nat. Commun. 11, 4031 (2020)