Prof. Dr. Katharina Timper: Specialist in Endocrinology, Diabetology & Metabolism

Director; Specialist in Endocrinology, Diabetology & Metabolism

Prof. Dr. med. Katharina Timper

Academic Career and Research Areas

Prof. Dr. Katharina Timper is a physician-scientist specializing in endocrinology, diabetology and metabolism, with a particular focus on the neuroscience of eating behavior and obesity. She studied human medicine at the University of Freiburg im Breisgau and subsequently completed specialist training in internal medicine and endocrinology in Switzerland, earning her board certification in Endocrinology, Diabetology and Metabolism in 2016 and a Swiss diploma in nutritional medicine in 2023.

 

Prior to joining Helmholtz Munich, Prof. Timper held a leading position at the University Hospital Basel, where she directed the interdisciplinary obesity center, the clinical nutrition unit, and the outpatient clinic for eating disorders. As the holder of an Eccellenza Professorship of the Swiss National Science Foundation, she led her own independent research group at the University of Basel, investigating the neurobiological mechanisms underlying obesity and metabolic regulation.

 

Since May 2025, Prof. Timper serves as Chair of Clinical Nutritional Medicine and Medical Director at the TUM University Hospital, completing the scientific leadership team of the Else Kröner Fresenius Centre for Nutritional Medicine (EKFZ). Together with co-director Dr. Tim Gruber, she is currently building up the Institute for Translational Metabolism Research (ITMR) at the Helmholtz Diabetes Center, where her group investigates how the brain contributes to metabolic regulation in the context of obesity and eating disorders.

Fields of Work and Expertise

Obesity & Metabolic Disease Neuroscience of Eating Behaviour  Clinical Nutritional Medicine Eating Disorders

Professional Background

2005 - 2011

Medical Studies

University of Freiburg im Breisgau, Germany

2011

Board Certification FMH - Internal Medicine

Swiss Medical Association

2016

Board Certification FMH — Endocrinology, Diabetology & Metabolism

Swiss Medical Association

2023

Swiss Diploma in Nutritional Medicine

2018 - 2025

Head, Outpatient Clinic for Eating Disorders

University Hospital Basel, Switzerland

2018 - 2025

Director, Interdisciplinary Obesity Centre & Clinical Nutrition

University Hospital Basel, Switzerland

2019 - 2025

Eccellenza Professor (SNF) & Independent Research Group Leader

University of Basel, Switzerland

2025 - Current

Director, Institute for Translational Metabolism Research (ITMR)

Helmholtz Diabetes Center, Helmholtz Munich

2025 - Current

Chair of Clinical Nutritional Medicine & Medical Director

TUM University Hospital / Else Kröner Fresenius Centre for Nutritional Medicine (EKFZ), Munich

Honors and Awards

  • 2019: Eccellenza Professorship — Swiss National Science Foundation (SNF)
  • 2018: Hemmi Prize for outstanding research in endocrinology
  • 2016: Award of the Swiss Diabetes Foundation

 

Key Publications

2020 Cell Metabolism

Timper K, Del Río-Martín A, Cremer AL, Bremser S, Alber J, Giavalisco P, Varela L, Heilinger C, Nolte H, Trifunovic A, Horvath TL, Kloppenburg P, Backes H, Brüning JC.

GLP-1 Receptor Signaling in Astrocytes Regulates Fatty Acid Oxidation, Mitochondrial Integrity, and Function
2019 Cell Reports

Hess ME*, Brüning JC, Timper K* (co-corresponding)

Ceramide Accumulation in Skeletal Muscle Promotes Insulin Resistance via Distinct Mechanisms
2018 Cell Reports

Timper K, Paeger L, Sánchez-Lasheras C, Varela L, Jais A, Nolte H, Vogt MC, Hausen AC, Heilinger C, Evers N, Patke A, Trifunovic A, Horvath TL, Kloppenburg P, Brüning JC.

Mild Impairment of Mitochondrial OXPHOS Promotes Fatty Acid Utilization in POMC Neurons and Improves Glucose Homeostasis in Obesity
2017 Cell Reports

Timper K, Denson JL, Steculorum SM, Heilinger C, Engström-Ruud L, Wunderlich CM, Rose-John S, Wunderlich FT, Brüning JC.

IL-6 Improves Energy and Glucose Homeostasis in Obesity via Enhanced Central IL-6 trans-Signaling
2017 Cell Metabolism

Dalmas E*, Lehmann FM*, Dror E, Wueest S, Thienel C, Borsigova M, Stawiski M, Träber C, Timper K, Böni-Schnetzler M, Donath MY, Konrad D.

IL-6/Stat3-Dependent Induction of a Distinct, Obesity-Associated NK Cell Subpopulation Deteriorates Energy and Glucose Homeostasis
2016 Gastroenterology

Timper K*, Dalmas E*, Dror E, Ruber S, Thienel C, Sauter NS, Bouzakri K, Bédat B, Pattou F, Kerr-Conte J, Böni-Schnetzler M, Donath MY.

Glucose-Dependent Insulinotropic Peptide Stimulates Glucagon-Like Peptide 1 Production by Pancreatic Islets via Interleukin 6, Produced by α Cells
2016 Cell

Steculorum SM, Ruud J, Karakasilioti I, Backes H, Engström Ruud L, Timper K, Hess ME, Tsaousidou E, Mauer J, Vogt MC, Paeger L, Bremser S, Klein AC, Morgan DA, Frommolt P, Brinkkötter PT, Hammerschmidt M, Benzing T, Rahmouni K, Wunderlich FT, Kloppenburg P, Brüning JC.

AgRP Neurons Control Systemic Insulin Sensitivity via Myostatin Expression in Brown Adipose Tissue
2013 The Lancet

Moran A, Bundy B, Becker DJ, DiMeglio LA, Gitelman SE, Goland R, Greenbaum CJ, Herold KC, Marks JB, Raskin P, Sanda S, Schatz D, Wherrett DK, Wilson DM, Krischer JP, Skyler JS; Type 1 Diabetes TrialNet Canakinumab Study Group; AIDA Study Group (incl. Timper K)

Interleukin-1 Antagonism in Type 1 Diabetes of Recent Onset: Two Multicentre, Randomised, Double-Blind, Placebo-Controlled Trials

Networks and Affiliations

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