Bioengineering Center

Institute for Intelligent Biotechnologies

A fundamental challenge in modern science is understanding how the brain functions in health and disease. The Institute for Intelligent Biotechnologies (iBIO) is interested in elucidating the mechanisms leading to neurological diseases and aging, particularly stroke and dementia.

A fundamental challenge in modern science is to understand how the brain functions in health and disease. The Institute for Intelligent Biotechnologies (iBIO) is interested in elucidating the mechanisms leading to neurological diseases and aging, particularly stroke and dementia.

Rendering of a Neuron on blue background and yellow light flashes

About our Institute

Our Research

Our laboratory is interested in understanding key mechanisms leading to neurodegeneration after acute brain injuries: stroke and dementia. We take a multidisciplinary approach to this quest by using advanced neuroscience imaging, genetic engineering, nanotechnology, and artificial intelligence.

While many diseases affect the entire body, research is usually conducted on the tissue of interest. To overcome potential bias, and discover previously unnoticed essential cellular and molecular mechanisms in health and disease, we use a holistic approach. Toward this goal, we have developed novel tissue transparency methods allowing 3D histology on intact organisms. We can now collect information on cells at sub-cellular levels in whole organs and organisms without sectioning. Obtained imaged data for example can for the first time present complete neuronal connectivity at a single neuronal level, and determine what goes wrong in neurological diseases.

Our Team

Institute: Scientists at iBIO

Porträt Ali Ertürk
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Hintergrund: HDC Foyer
Dr. Ali Ertürk

Research Director Institute for Intelligent Biotechnologies, iBIO

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Dr. Mihail Todorov

Postdoc

Dr. Harsharan S. Bhatia

Postdoc

Marin Bralo

Technical assistant

Dr. Doris Kaltenecker

Postdoc

Johannes Paetzold

Master Student

Ilgin Kolabas

Ph. D. Student

Hongcheng Mai

PhD student

Zhouyi Rong

PhD student

Dr. Farida Hellal

Co-Deputy

Dr. Jennifer Modamio

Postdoc

Rami Al-Maskari

Ph.D. Student

Dr. Jie Luo

Postdoc

Izabela Horvath

Ph.D. Student

Karoline Kadletz

Ph.D Student

Mayar Ali

Ph.D Student

Luciano Höher

Master Student

Denise Jeridi

Biological Lab Technician

Xiaoshan Hu

Team Assistant

Stefanie Reitinger

Project Coordinator

Our News

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Whole-body 3D reconstructions, AI segmentations and supplementary videos are available via the interactive online atlas at https://discotechnologies.org/MouseMapper/. High-resolution figures and animations are available on request.

New Research Findings, Diabetes, IDC, Bioengineering, iBIO,

AI Atlas Reveals Hidden Whole-Body-Damage Caused by Obesity

Researchers at Helmholtz Munich, the Ludwig Maximilians University Munich (LMU) and collaborating institutions have developed an artificial intelligence (AI) framework that maps disease-related changes throughout the entire mouse body at cellular…

Ali Ertürk with transparent mouse

AI, Bioengineering, iBIO,

Ali Ertürk’s Journey in Transformative Biomedical Imaging

Imagine a world where the most intricate networks and processes within whole bodies are visible – down to the level of individual molecules. This is what Ali Ertürk’s pioneering research makes possible, opening up new possibilities for medicine and…

Lipid nanoparticles

AI, New Research Findings, Bioengineering, iBIO,

SCP-Nano: A New Technology to Visualize Nanocarriers in Cells and Tissues

How can we ensure that life-saving drugs or genetic therapies reach their intended target cells without causing harmful side effects? Researchers at Helmholtz Munich, Ludwig-Maximilians-Universität (LMU) and Technical University Munich (TUM) have…

Microscopic View of Coronavirus

New Research Findings, Bioengineering, iBIO,

Long COVID: SARS-CoV-2 Spike Protein Accumulation Linked to Long-Lasting Brain Effects

Researchers from Helmholtz Munich and Ludwig-Maximilians-Universität (LMU) have identified a mechanism that may explain the neurological symptoms of Long COVID. The study shows that the SARS-CoV-2 spike protein remains in the brain’s protective…

Ali Ertürk_KI-Erweiterung für Website

Awards & Grants, ITERM,

Ali Ertürk Wins 2024 Falling Walls Award

Prof. Ali Ertürk from Helmholtz Munich and the Ludwig-Maximilians-University Munich (LMU) has won the 2024 Falling Walls Award in Life Sciences for his pioneering research that integrates advanced tissue clearing techniques with AI. This breakthrough…

DELiVR mouse brain

New Research Findings, Bioengineering, ITERM,

Advanced Brain Science Without Coding Expertise

Researchers at Helmholtz Munich and the LMU University Hospital Munich introduce DELiVR, offering a new AI-based approach to the complex task of brain cell mapping. The deep learning tool democratizes advanced neuroscience by eliminating the need for…

Contact

Stefanie Reitinger

Project Coordinator

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