Photonic Biosciences and Technologies

Bioengineering Center

Photonic Biosystems and Technologies

Photonic Biosystems and Technologies (PBT) synthesizes novel classes of nanomaterials with unique chemical and optical properties. We aim to apply these materials towards the development of unconventional approaches to biological imaging and sensing.

Photonic Biosystems and Technologies (PBT) synthesizes novel classes of nanomaterials with unique chemical and optical properties. We aim to apply these materials towards the development of unconventional approaches to biological imaging and sensing.

About our Research

The most compelling characteristic of nanoscale materials is the emergence of different physical phenomena upon the shrinking of dimensions. We are interested in exploiting these unique properties of the nanoscopic world to develop a new toolkit that will help us understand, and perhaps ultimately control, biological systems.

We are a diverse team of researchers asking interdisciplinary questions, and engaging in multidisciplinary approaches, in the hopes of achieving transdisciplinary outcomes (transcending disciplines).

Our Approach

Creative combinations of engineered nanomaterials and nano-optical detection allow us to develop new platforms for measuring, and potentially controlling, biological processes in previously unexplored ways.

Our Team

Jian Cui, Cui Lab, PI
Hintergrund: HDC Foyer
Dr. Jian Cui

Head of Research Unit and Principal Investigator, PBT

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Luciano M. Santino
Dr. Luciano M. Santino

Deputy Head / Senior Scientist, PBT

Dr. Zhizi Jing

Senior Scientist, PBT

Feng Zhao

Ph.D. Student, PBT

Moritz Roman Schepp

Ph.D. Student, PBT

Sruthi Sunil

Ph.D. Student, PBT

Lukas Nagy

Ph.D. Student, PBT

Minchan Kim

Ph.D. Student, PBT

Dr. Ruyu Ma

Postdoc, PBT

Recent Publications

2026 in
In: (23rd IEEE International Symposium on Biomedical Imaging, ISBI 2026, 8-11 April 2026, London). 2026. ( ; 2026-April)

Liu, Y. ; Ma, R. ; Navab, N. ; Cui, J. ; Peng, T.

CURVFUSE: Field-Curvature-Aware Multi-Focus Fusion for Bioluminescence Imaging.
Nat. Methods, DOI: 10.1038/s41592-025-02694-3 (2025)

Ma, R. ; Santino, L.M. ; Chobola, T. ; Armbrust, N. ; Geilenkeuser, J. ; Sukumaran, S. ; Jing, Z. ; Levkina, A. ; Ridderbeek, K. ; Peng, T. ; Truong, D.J.J. ; Doll, S. ; Westmeyer, G.G. ; Cui, J.

A telescopic microscope equipped with a quanta image sensor for live-cell bioluminescence imaging.
ACS App. Optic. Mat. 3, 676-688 (2025)

Zhou, J. ; Ridderbeek, K. ; Zou, P. ; Naden, A.B. ; Gaussmann, S. ; Song, F. ; Falter-Braun, P. ; Kay, E.R. ; Sattler, M. ; Cui, J.

Modular nanoparticle platform for solution-phase optical sensing of protein-protein interactions.
J. Phys. Chem. Lett. 13, 4145-4151 (2022)

Cocina, A. ; Brechbühler, R. ; Vonk, S.J.W. ; Cui, J. ; Rossinelli, A.A. ; Rojo, H. ; Rabouw, F.T. ; Norris, D.J.

Nanophotonic approach to study excited-state dynamics in semiconductor nanocrystals.

Contact

Jian Cui, Cui Lab, PI
Hintergrund: HDC Foyer
Dr. Jian Cui

Head of Research Unit and Principal Investigator, PBT

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