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Kidney tubular cells dying by ferroptosis
Helmholtz Munich | © MCD

Molecular Targets and Therapeutics Center Metabolism and Cell Death

The Institute of Metabolism and Cell Death (MCD) aims to elucidate the molecular mechanisms underlying life and death decisions in (patho-)physiological contexts. Understanding these mechanisms is central to both the identification of biomarkers and the development of new therapies to combat degenerative diseases and cancer.

The Institute of Metabolism and Cell Death (MCD) aims to elucidate the molecular mechanisms underlying life and death decisions in (patho-)physiological contexts. Understanding these mechanisms is central to both the identification of biomarkers and the development of new therapies to combat degenerative diseases and cancer.

News from our Institute

Our Scientists at Metabolism and Cell Death

Marcus Conrad_freigestellt

Prof. Dr. Marcus Conrad

Director Metabolism and Cell Death View profile
Porträt Bettina Proneth

Dr. Bettina Proneth

Deputy Director
Porträt Jens Hansen

Dr. Jens Hansen

Group Leader
Porträt Marceler Aldrovandi

Dr. Maceler Aldrovandi

Group Leader
Porträt Sebastian Doll

Dr. Sebastian Doll

Group Leader

Latest Publications of Our Institute

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2025 Scientific Article in Nature

Cañeque, T. ; Baron, L. ; Müller, S. ; Carmona, A. ; Colombeau, L. ; Versini, A. ; Solier, S. ; Gaillet, C. ; Sindikubwabo, F. ; Sampaio, J.L. ; Sabatier, M. ; Mishima, E. ; Picard-Bernes, A. ; Syx, L. ; Servant, N. ; Lombard, B. ; Loew, D. ; Zheng, J. ; Proneth, B. ; Thoidingjam, L.K. ; Grimaud, L. ; Fraser, C.S. ; Szylo, K.J. ; Der Kazarian, E. ; Bonnet, C. ; Charafe-Jauffret, E. ; Ginestier, C. ; Santofimia-Castaño, P. ; Estaras, M. ; Dusetti, N. ; Iovanna, J.L. ; Cunha, A.S. ; Pittau, G. ; Hammel, P. ; Tzanis, D. ; Bonvalot, S. ; Watson, S. ; Gandon, V. ; Upadhyay, A. ; Pratt, D.A. ; Freitas, F.P. ; Friedmann Angeli, J.P. ; Stockwell, B.R. ; Conrad, M. ; Ubellacker, J.M. ; Rodriguez, R.

Activation of lysosomal iron triggers ferroptosis in cancer.

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Institute Director

Marcus Conrad_freigestellt

Prof. Dr. Marcus Conrad

Director Metabolism and Cell Death

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Institute Office

Silvia Köhn

Office