Epigenetics @HelmholtzMunich
Dozens of researchers @Helmholtz Munich join forces to reveal the myriad of secrets of Epigenetics.
Learn more about us below.
Dozens of researchers at Helmholtz Munich joined forces
to reveal the myriad of secrets of Epigenetics.
The Epigenetics@HelmholtzMunich Community Research consists of almost 30 labs from 17 Helmholtz Munich institutes, committed to performing ground-breaking research in the field of epigenetics. These groups are pioneers in their respective disciplines, utilizing cutting edge techniques to answer the complex questions of today.
The topics studied by the community include: stem cells, cellular plasticity, metabolism, diabetes, computational biology, epidemiology, immunology, development, and systems biology.
Seminars & Events
Recent Publications
Petzold, A. ; Wessely, A. ; Schliep, S. ; Jiang, H. ; Tran, M. ; Koch, E.A. ; Peng, T. ; Starz, H. ; Berking, C. ; Marr, C. ; Heppt, M.V.
Weakly supervised deep learning for cutaneous squamous and basal cell carcinoma in whole-slide histopathology.Malagoli, G. ; Hanel, P. ; Danese, A. ; Wolf, G. ; Colomé-Tatché, M.
Geometry-aware graph attention networks to explain single-cell chromatin states and gene expression with SEAGALL.Balan, T. ; Petitalot, A. ; Albert, J.R. ; Abbou, L. ; Chevreux, G. ; Al-Sady, B. ; Aygenli, B.Ö. ; Bartke, T. ; Margueron, R. ; Duharcourt, S.
A H3K27me3 reader complex couples H3K27me3 accumulation to nascent transcription of transposable elements in Paramecium.Armbrust, N. ; Grosshauser, M. ; Geilenkeuser, J. ; Stroppel, L. ; Jozinovic, M. ; Levermann, H. ; Panne, T. ; Wißmann, J. ; Goelitz, L. ; Schmidt, S. ; Orschmann, T. ; Rusha, E. ; Steinmaßl, E. ; Widenmeyer, F. ; Warsing, N. ; Sabry, M. ; Sultanbai, A. ; Santl, T. ; Geerlof, A. ; Berezin, O. ; Bodea, S.V. ; Moretti, A. ; Schneider, S. ; Theis, F.J. ; Gagneur, J. ; Truong, D.J.J. ; Westmeyer, G.G.
Non-destructive transcriptomics via vesicular export.Ghirotto, B. ; Gonçalves, L.E. ; Ruder, V. ; James, C. ; Gerasimova, E. ; Rizo, T. ; Wend, H. ; Farrell, M. ; Gerez, J.A. ; Prymaczok, N.C. ; Kuijs, M. ; Shulman, M. ; Hartebrodt, A. ; Prots, I. ; Gessner, A. ; Vieth, M. ; Zunke, F. ; Winkler, J. ; Blumenthal, D.B. ; Theis, F.J. ; Riek, R. ; Günther, C. ; Neurath, M. ; Gupta, P. ; Winner, B.
TNF alpha unmasks enteric malate aspartate shuttle dysfunction bridging Parkinson disease and intestinal inflammation.Dasdelen, M.F. ; Kukuljan; I. ; Lienemann, P. ; Ozlugedik, F. ; Sadafi, A. ; Hehr, M. ; Spiekermann, K. ; Pohlkamp, C. ; Marr, C.
AI-based hematological malignancy prediction from peripheral blood smears in a large diagnostic laboratory cohort.Koutrouli, M. ; Finotello, F. ; Schoof, E.M. ; Roussos, P. ; scverse Proteomics Consortium (Theis, F.J.) ; scverse Proteomics Consortium (Salas, S.M.)
Unpaired data as a first-order challenge in single-cell and spatial proteomics.Kazeminia, S. ; Marr, C. ; Rieck, B.
Topological Inductive Bias fosters Multiple Instance Learning in Data-Scarce Scenarios.Hankofer, V. ; Ghirardo, A. ; Obermaier, L. ; Poschet, G. ; Kumar, J.S. ; Gross, I. ; Durner, J. ; Rychlik, M. ; Wirtz, M. ; Hell, R. ; Schnitzler, J.-P. ; Groth, M.
Photorespiration is linked to DNA methylation by formate as a one-carbon source.Mueller, S. ; de Andrade Krätzig, N. ; Tschurtschenthaler, M. ; Silva, M.G. ; Thordsen, C. ; Trozzo, R. ; Simon, P. ; Saab, F. ; Kaltenbacher, T. ; Zukowska, M. ; Lucarelli, D. ; Öllinger, R. ; Griger, J. ; Groß, N. ; Groll, T. ; Löprich, J. ; Zaurito, A.E. ; Schömig, L.R. ; Bugter, J.M. ; Bärthel, S. ; Falcomatà, C. ; Strong, A. ; Brandt, C. ; Najajreh, M. ; Papargyriou, A. ; Maresch, R. ; Collins, K.A.N. ; Sailer, D. ; Schneeweis, C. ; Burger, S. ; Fröhlich, L.M. ; Klement, C. ; Belka, A. ; Montero, J.J. ; Jungwirth, U. ; Reichert, M. ; Moser, M. ; Neumann, J. ; Vassiliou, G. ; Cadiñanos, J. ; Varela, I. ; Marr, C. ; Alonso, D.F. ; Lollini, P.L. ; Zhao, J. ; Chesler, L. ; Isacke, C.M. ; Riedel, A. ; Braun, C.J. ; Sos, M.L. ; Beleggia, F. ; Reinhardt, H.C. ; Musteanu, M. ; Barbacid, M. ; Quante, M. ; Schmidt-Supprian, M. ; Schneider, G. ; Clare, S. ; Lawley, T.D. ; Dougan, G. ; Steiger, K. ; Conte, N. ; Bradley, A. ; Rad, L. ; Saur, D. ; Rad, R.
A disease model resource reveals core principles of tissue-specific cancer evolution.Schmidt, T. ; Kumar, C.N. ; Stricker, S.H.
Gene anschalten statt umbauen: CRISPR aktiviert Zellprogramme ohne DNA-Eingriff.Bader, J.M. ; Makarov, C. ; Richter, S. ; Strauss, M.T. ; Held, F. ; Wahle, M. ; Lorenz, M.B. ; Pöschl, L. ; Skowronek, P. ; Thielert, M. ; Berthele, A. ; Zeng, W.F. ; Ammar, C. ; Bludau, I. ; Schubert, B. ; Theis, F.J. ; Gasperi, C. ; Hemmer, B. ; Mann, M.
Large-scale proteomics across neurological disorders uncovers biomarker panel and targets in multiple sclerosis.Richter, T. ; Wang, W. ; Palma, A. ; Theis, F.J.
Generative models of cell dynamics: From Neural ODEs to flow matching.Maier, L. ; Sun, Y. ; Kronberg, J. ; Abner, E. ; Coley, K. ; Marenholz, I. ; Weiss, S. ; Foraita, R. ; Karramass, T. ; Mykkänen, J. ; Hernandez-Pacheco, N. ; Wang, C.A. ; Kitaba, N.T. ; Pechlivanis, S. ; Bouzigon, E. ; Tingskov Pedersen, C.E. ; Schoos, A.M. ; Curtin, J. ; Kress, S. ; Hernangomez-Laderas, A. ; Foppiano, F. ; Ashley, S. ; Batini, C. ; Bryant, L. ; Homuth, G. ; Gieger, C. ; Gilles, S. ; Lyytikäinen, L.P. ; Rovio, S. ; Pahkala, K. ; Vernet, R. ; Valenta, R. ; Llop, S. ; Torrent, M. ; Böck, A. ; Tang, M.L.K. ; Schmidt-Weber, C.B. ; Metspalu, A. ; Esko, T. ; Sprikkelman, A.B. ; John, C. ; Lee, Y.A. ; Beyer, K. ; Völzke, H. ; Pigeot, I. ; Traidl-Hoffmann, C. ; Duijts, L. ; Lu, H. ; Raitakari, O.T. ; Lehtimäki, T. ; Kähönen, M. ; Tio, C.H.L. ; Melén, E. ; Pennell, C.E. ; Holloway, J.W. ; von Mutius, E. ; Siroux, V. ; Bønnelykke, K. ; Custovic, A. ; Simpson, A. ; Schikowski, T. ; Bilbao, J.R. ; Schaub, B. ; Peters, R. ; Kersten, E.T.G. ; Vonk, J.M. ; Thiering, E. ; Peters, A. ; Koppelman, G.H. ; Standl, M.
Meta-analysis of genome-wide association studies of food allergy and IgE-sensitization.Li, J. ; Wang, J. ; Ibarra Del Rio, I.A. ; Cheng, X. ; Luecken, M. ; Lu, J. ; Monavarfeshani, A. ; Yan, W. ; Zheng, Y. ; Zuo, Z. ; Colborn, S.L.Z. ; Cortez, B.S. ; Owen, L.A. ; Wick, B. ; Bao, X. ; Choi, J. ; Haeussler, M. ; Tran, N.M. ; Shekhar, K. ; Sanes, J.R. ; Stout, J.T. ; Chen, S. ; Li, Y. ; DeAngelis, M.M. ; Theis, F.J. ; Chen, R.
Author Correction: Single-cell atlas of the transcriptome and chromatin accessibility in the human retina.Bahrami, M. ; Richter, T. ; Schmacke, N.A. ; Egea Lavandera, A. ; Theis, F.J.
From modality-specific to compositional foundation models for cell biology.Langstein-Skora, I. ; Schmid, A. ; Huth, F. ; Shabani, D. ; Spechtenhauser, L. ; Likhodeeva, M. ; Kunert, F. ; Metzner, F.J. ; Emenecker, R.J. ; Richardson, M.O. ; Aftab, W. ; Götz, M.J. ; Payer, S. ; Pietrantoni, N. ; Valka, V. ; Ravichandran, S.K. ; Bartke, T. ; Karl-Peter, H. ; Gerland, U. ; Korber, P. ; Holehouse, A.S.
Sequence and chemical specificity define the functional landscape of intrinsically disordered regions.Stephan, N. ; Halama, A. ; Thareja, G. ; Sarwath, H. ; Grallert, H. ; Peters, A. ; Gieger, C. ; Schmidt, F. ; Graumann, J. ; Suhre, K.
Identification of protein signatures reflecting latent variation in aptamer-based affinity proteomics.