Portrait of Dr. Michael Heinzinger, Institute of Computational Biology

Principal Investigator, Institute of Computational Biology

Dr. Michael Heinzinger

"I am convinced that pairing nature’s billion-year biochemical innovations in proteins with advances in AI can help build a more sustainable future and advance human health."

Visit my Lab  

Academic Career and Research Areas

Dr. Michael Heinzinger studied bioinformatics at the Technical University of Munich and Ludwig Maximilian University of Munich. He completed his doctoral research with Prof. Burkhard Rost, where he pioneered the use of language models for protein sequences, advancing representation learning in this domain. He then worked as a postdoctoral researcher in the Rost Lab on multimodal protein language models and as a machine learning researcher at Sanofi, focusing on nanobody optimization. Since March 2025, he leads a tenure-track research group at the Institute of Computational Biology (ICB) at Helmholtz Munich.

Dr. Michael Heinzinger's research lies at the intersection of deep learning and computational biology, aiming to illuminate the "dark matter" of the protein universe and enable the design and optimization of proteins. His work develops foundation models that leverage rapidly growing biological data across sequence, structure, and function, with a focus on multimodal representation learning and evolution-guided strategies for improving natural proteins.

Fields of Work and Expertise

Computational Biology

Deep Learning

Protein Language Models

Protein design & engineering

Professional Background

2025

Recipient of large-scale compute grant (Gauss AI Compute Competition), in progress

2023

Finalist of Deutscher Studienpreis

2022

PhD defended with honors (summa cum laude)

2020

Recipient of large-scale compute grant (Covid-19 HPC Consortium), leading to a tool (protein language model) which fundamentally changed how we process protein sequence data

Honors and Awards

  • 2023 -Detuscher Studienpreis Finalist

Media Coverage

Research Highlight

"High-Performance Computing and Artificial Intelligence Decode the Language of Life in Proteins"

Read more

Research Project

"Accelerate SARS-CoV-2 research with transfer learning using pre-trained language modeling model"

Read more

Podcast

"Podcast: Episode 3, Predicting protein structure"

Listen now

Building a better world?

Join our team.