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Blaauwendraad, S.M. ; Kamphuis, A.S.J. ; Ruiz Ojeda, F.J. ; Brandimonte-Hernández, M. ; Flores-Ventura, E. ; Abrahamse-Berkeveld, M. ; Collado, M.C. ; van Diepen, J.A. ; Iozzo, P. ; Knipping, K. ; van Loo-Bouwman, C.A. ; Gil, Á. ; Gaillard, R.
Risk factors in the first 1000 days of life associated with childhood obesity: A systematic review and risk factor quality assessment.Altun, I. ; Vo, K.H.D. ; Walia, S.R. ; Yan, X. ; Singh, I. ; Karlina, R. ; Miok, V. ; Kang, L. ; Reichenbach, V.K. ; Israel, A. ; Lutter, D. ; Perocchi, F. ; Ussar, S.
Igf2 regulates early postnatal DPP4+ preadipocyte pool expansion.Hammer, E. ; Flynn, C. ; Rössler, J. ; Erder, J. ; Napieralski, R. ; Fricke, L. ; Campbell, B. ; Feuerherd, M. ; Esslinger, F. ; von Brunn, A. ; Weber, T. ; King, S. ; Tan, S. ; Brisson, A.R. ; Protzer, U. ; Schricker, G. ; Gärtner, K. ; Ebert, G. ; Moretti, A. ; Klein, F. ; Knoops, K. ; Heeren, R. ; Hammerschmidt, W. ; Zeidler, R. ; Wilhelm, O. ; Knolle, P.A. ; Höchst, B.
Prediction of COVID-19 disease progression by multiparametric analysis of circulating extracellular vesicles with flow cytometry.Latic, N. ; Lari, A. ; Sun, N. ; Zupcic, A. ; Oubounyt, M. ; Falivene, J. ; Buck, A. ; Hofer, M. ; Chang, W. ; Kuebler, W.M. ; Baumbach, J. ; Walch, A. ; Grabner, A. ; Erben, R.G.
Deletion of cardiac fibroblast growth factor-23 beneficially impacts myocardial energy metabolism in left ventricular hypertrophy.Ussar, S.
Targeting adipose inflammation and energy expenditure to sustain metabolic health after weight loss.Krier, J. ; Spähn, D. ; Lopez, D.A.J. ; Nono, J.L. ; Seigner, J. ; Ussar, S. ; Lukowski, R. ; Birkenfeld, A.L. ; Sancar, G.
PDE4D and PDE3B orchestrate distinct cAMP microdomains in 3T3-L1 adipocytes.Singh, I. ; Onogi, Y. ; Cardoso Micu Menezes, F.M. ; Khasanova, D. ; Kang, L. ; Wang, C. ; Ruiz-Trave, J. ; Sharma, S. ; Khalil, A. ; Reichenbach, V.K. ; Shi, Y. ; Flatley, A. ; Yan, X. ; Israel, A. ; Dragano, N.R.V. ; Aguilar-Pimentel, J.A. ; Hoffmann, A. ; Ghosh, A. ; Noé, F. ; Wolfrum, C. ; Cucuruz, S. ; König, A.-C. ; Burtscher, I. ; Hauck, S.M. ; Lickert, H. ; Hofmann, S.M. ; Feederle, R. ; Schriever, S.C. ; Hernandez-Bautista, R. ; Sancar, G. ; Cebrian Serrano, A. ; Tetko, I.V. ; Fuchs, H. ; Gailus-Durner, V. ; Blüher, M. ; Hrabě de Angelis, M. ; Ussar, S.
NRAC controls CD36-mediated fatty acid uptake in adipocytes and lipid clearance in vivo.Waas, D. ; Juraschitz, M. ; Chen, Y.A. ; Waltenberger, H. ; Hammerschmidt, W. ; Zeidler, R. ; Molinaro, S. ; Gärtner, K.
Development of broadly applicable reference EVs expressing horseradish peroxidase.Wilhelm, A.D. ; Flynn, C. ; Hammer, E. ; Rössler, J. ; Haller, B. ; Napieralski, R. ; Leuthner, M. ; Tosheska, S. ; Knoops, K. ; Mathew, A. ; Ciarimboli, G. ; Kranich, J. ; Flaskamp, L. ; King, S. ; Gevensleben, H. ; Emslander, Q. ; Pastucha, A. ; Reisbeck, M. ; Rief, L. ; Bronger, H. ; Dreyer, T. ; Bausch, A.R. ; Pichlmair, A. ; Brocker, T. ; Zeidler, R. ; Hammerschmidt, W. ; Piedavent-Salomom, M. ; López-Iglesias, C. ; Schricker, G. ; Haydn, O. ; Kiechle, M. ; Grill, S.W. ; Heeren, R. ; Knolle, P.A. ; Wilhelm, O. ; Höchst, B.
Two-dimensional analysis of plasma-derived extracellular vesicles to determine the HER2 status in breast cancer patients.Yuzbashian, E. ; Fernando, D.N. ; Jacobs, R.L. ; Lesker, T. ; Strowig, T. ; Ussar, S. ; Chan, C.B.
A comparison of the effects of milk, yogurt, and cheese on insulin sensitivity, hepatic steatosis, and gut microbiota in diet-induced obese male mice.Chen, Y.-F. A. ; Mocanu, B. ; Akidil, E. ; Pich, D. ; Mautner, J. ; Sugden, B. ; Hammerschmidt, W.
Assessing the fitness of Epstein-Barr virus following its reactivation.I. Álvarez‐Mercado, A. ; López‐Plaza, B. ; Plaza‐Díaz, J. ; Arcos-Castellanos, L. ; Ruiz Ojeda, F.J. ; Brandimonte-Hernández, M. ; Feliú, J. ; Hummel, T. ; Milla, S.P. ; Gil, Á.
Miraculin can contribute to a reduction in inflammatory biomarkers and cachexia in malnourished patients with cancer and taste disorders.Morath, V. ; Maurer, S. ; Feuchtinger, A. ; Walser, R. ; Schlapschy, M. ; Bolze, F. ; Metzler, T. ; Bruder, J. ; Steiger, K. ; Walch, A.K. ; Klingenspor, M. ; Skerra, A.
Long-acting human PASylated leptin reaches the murine central nervous system and offers potential for optimized replacement therapy.Coupland, C. ; Sun, N. ; Khalil, A. ; Karaoglu, Ö.E. ; Liskiewicz, A. ; Liskiewicz, D. ; Grandl, G. ; Akindehin, S.E. ; Maity-Kumar, G. ; Yang, B. ; Finan, B. ; Knerr, P.J. ; Douros, J.D. ; Walch, A.K. ; DiMarchi, R. ; Tschöp, M.H. ; Müller, T.D. ; Novikoff, A.
Estrogenic activity of E2-conjugated GLP-1 is mediated by intracellular endolysosomal acidification and estrone metabolism.Luo, J. ; Molbay, M. ; Chen, Y. ; Horvath, I. ; Kadletz, K. ; Kick, B. ; Zhao, S. ; Al-Maskari, R. ; Singh, I. ; Ali, M. ; Bhatia, H.S. ; Minde, D.-P. ; Negwer, M. ; Höher, L. ; Calandra, G.M. ; Groschup, B. ; Su, J. ; Kimna, C. ; Rong, Z. ; Galensowske, N. ; Todorov, M.I. ; Jeridi, D. ; Ohn, T.-L. ; Roth, S. ; Simats, A. ; Singh, V. ; Khalin, I. ; Pan, C. ; Arus, B.A. ; Bruns, O.T. ; Zeidler, R. ; Liesz, A. ; Protzer, U. ; Plesnila, N. ; Ussar, S. ; Hellal, F. ; Paetzold, J.C. ; Elsner, M. ; Dietz, H. ; Ertürk, A.
Nanocarrier imaging at single-cell resolution across entire mouse bodies with deep learning.Wang, Q. ; Sun, N. ; Zhang, C.-Y. ; Kunzke, T. ; Zens, P. ; Feuchtinger, A. ; Berezowska, S. ; Walch, A.K.
Metabolic heterogeneity in tumor cells impacts immunology in lung squamous cell carcinoma.Wang, C. ; Leong, M.M. ; Ding, W. ; Narita, Y. ; Liu, X. ; Wang, H. ; Yiu, S.P.T. ; Lee, J. ; Zhao, K.R.S. ; Cui, A. ; Gewurz, B. ; Hammerschmidt, W. ; Teng, M. ; Zhao, B.
Viral oncogene EBNALP regulates YY1 DNA binding and alters host 3D genome organization.Wang, Y. ; Rambold, U. ; Fiedler, P. ; Babushku, T. ; Tapken, C.L. ; Hoefig, K.P. ; Hofer, T.P. ; Adler, H. ; Yildirim, A.Ö. ; Strobl, L.J. ; Zimber-Strobl, U.
CD30 influences germinal center B-cell dynamics and the expansion of IgG1-switched B cells.Dietz, A. ; Subedi, P. ; Azimzadeh, O. ; Duchrow, L. ; Kaestle, F. ; Paetzold, J.C. ; Katharina Payer, S. ; Hornhardt, S. ; von Toerne, C. ; Hauck, S.M. ; Kempkes, B. ; Kuklik-Roos, C. ; Brandes, D. ; Borkhardt, A. ; Moertl, S. ; Gomolka, M.
The chromosome passenger complex (CPC) components and its associated pathways are promising candidates to differentiate between normosensitive and radiosensitive ATM-mutated cells.Klinger, B. ; Rausch, I. ; Sieber, A. ; Kutz, H. ; Kruse, V. ; Kirchner, M. ; Mertins, P. ; Kieser, A. ; Blüthgen, N. ; Kube, D.
Quantitative modeling of signaling in aggressive B cell lymphoma unveils conserved core network.Haunhorst, S. ; Dudziak, D. ; Scheibenbogen, C. ; Seifert, M. ; Sotzny, F. ; Finke, C. ; Behrends, U. ; Aden, K. ; Schreiber, S. ; Brockmann, D. ; Burggraf, P. ; Bloch, W. ; Ellert, C. ; Ramoji, A. ; Popp, J. ; Reuken, P. ; Walter, M. ; Stallmach, A. ; Puta, C.
Towards an understanding of physical activity-induced post-exertional malaise: Insights into microvascular alterations and immunometabolic interactions in post-COVID condition and myalgic encephalomyelitis/chronic fatigue syndrome.Danko, B. ; Hess J. ; Unger, K. ; Samaga, D. ; Walz, C. ; Walch, A.K. ; Sun, N. ; Baumeister, P. ; Zeng, P.Y.F. ; Walter, F. ; Marschner, S. ; Späth, R. ; Gires, O. ; Herkommer, T. ; Dazeh, R. ; Matos, T. ; Kreutzer, L. ; Matschke, J.B. ; Eul, K. ; Klauschen, F. ; Pflugradt, U. ; Canis, M. ; Ganswindt, U. ; Mymryk, J.S. ; Wollenberg, B. ; Nichols, A.C. ; Belka, C. ; Zitzelsberger, H. ; Lauber, K. ; Selmansberger, M.
Metabolic pathway-based subtypes associate glycan biosynthesis and treatment response in head and neck cancer.Juhász, B. ; Horváth, K. ; Kuti, D. ; Shen, J. ; Feuchtinger, A. ; Zhang, C.-Y. ; Bata-Vidács, I. ; Nagy, I. ; Kukolya, J. ; Witting, M. ; Baranyi, M. ; Ferenczi, S. ; Walch, A.K. ; Sun, N. ; Kovács, K.J.
Dipeptide metabolite, glutamyl-glutamate mediates microbe-host interaction to boost spermatogenesis.Sun, N. ; Krauss, T. ; Seeliger, C. ; Kunzke, T. ; Stöckl, B. ; Feuchtinger, A. ; Zhang, C.-Y. ; Voss, A. ; Heisz, S. ; Prokopchuk, O. ; Martignoni, M.E. ; Janssen, K.P. ; Claussnitzer, M. ; Hauner, H. ; Walch, A.K.
Inter-organ cross-talk in human cancer cachexia revealed by spatial metabolomics.Yuan, X.Q. ; Zhou, N. ; Song, S.J. ; Xie, Y.X. ; Chen, S.Q. ; Yang, T.F. ; Peng, X. ; Zhang, C.-Y. ; Zhu, Y.H. ; Peng, L.
Decoding the genomic enigma: Approaches to studying extrachromosomal circular DNA.Fischer, F. ; Mücke, J. ; Werny, L. ; Gerrer, K. ; Mihatsch, L. ; Zehetmaier, S. ; Riedel, I. ; Geisperger, J. ; Bodenhausen, M. ; Schulte-Hillen, L. ; Hoffmann, D. ; Protzer, U. ; Mautner, J. ; Behrends, U. ; Bauer, T. ; Körber, N.
Evaluation of novel Epstein-Barr virus-derived antigen formulations for monitoring virus-specific T cells in pediatric patients with infectious mononucleosis.Kohantorabi, M. ; Ugolotti, A. ; Sochor, B. ; Rössler, J. ; Wagstaffe, M. ; Meinhardt, A. ; Beck, E.E. ; Dolling, D.S. ; Garcia, M.B. ; Creutzburg, M. ; Keller, T.F. ; Schwartzkopf, M. ; Vayalil, S.K. ; Thuenauer, R. ; Guédez, G. ; Löw, C. ; Ebert, G. ; Protzer, U. ; Hammerschmidt, W. ; Zeidler, R. ; Roth, S.V. ; Di Valentin, C. ; Stierle, A. ; Noei, H.
Light-induced transformation of virus-like particles on TiO2.Liu, N. ; O'Connor, P. ; Gujrati, V. ; Shelar, D. ; Ma, X. ; Anzenhofer,P. ; Klemm, U. ; Su, X. ; Huang, Y. ; Kleigrewe, K. ; Feuchtinger, A. ; Walch, A.K. ; Sattler, M. ; Plettenburg, O. ; Ntziachristos, V.
Tuning the photophysical properties of cyanine by barbiturate functionalization and nanoformulation for efficient optoacoustics- guided phototherapy.Müller-Durovic, B. ; Jäger, J. ; Engelmann, C. ; Schuhmachers, P. ; Altermatt, S. ; Schlup, Y. ; Duthaler, U. ; Makowiec, C. ; Unterstab, G. ; Roffeis, S. ; Xhafa, E. ; Assmann, N. ; Trulsson, F. ; Steiner, R. ; Edwards-Hicks, J. ; West, J. ; Turner, L. ; Develioglu, L. ; Ivanek, R. ; Azzi, T. ; Dehio, P. ; Berger, C. ; Kuzmin, D. ; Saboz, S. ; Mautner, J. ; Löliger, J. ; Geigges, M. ; Palianina, D. ; Khanna, N. ; Dirnhofer, S. ; Münz, C. ; Bantug, G.R. ; Hess, C. ; Koller, M. ; Rossi, S. ; Stampf, S. ; Müller, N.J.
A metabolic dependency of EBV can be targeted to hinder B cell transformation.Teixeira Alves, L.G. ; Baumgardt, M. ; Langner, C. ; Fischer, M. ; Maria Adler, J. ; Bushe, J. ; Firsching, T.C. ; Mastrobuoni, G. ; Grobe, J. ; Hoenzke, K. ; Kempa, S. ; Gruber, A.D. ; Hocke, A.C. ; Trimpert, J. ; Wyler, E. ; Landthaler, M.
Protective role of the HSP90 inhibitor, STA-9090, in lungs of SARS-CoV-2-infected Syrian golden hamsters.Babushku, T. ; Lechner, M. ; Ehrenberg, S. ; Rambold, U. ; Schmidt-Supprian, M. ; Yates, A.J. ; Rane, S. ; Zimber-Strobl, U. ; Strobl, L.J.
Notch2 controls developmental fate choices between germinal center and marginal zone B cells upon immunization.Wang, J. ; Sun, N. ; Kunzke, T. ; Shen, J. ; Feuchtinger, A. ; Wang, Q. ; Meixner, R. ; Le Gleut, R. ; Haffner, I. ; Luber, B. ; Lordick, F. ; Walch, A.K.
Metabolic heterogeneity affects trastuzumab response and survival in HER2-positive advanced gastric cancer.Theobald, S.J. ; Fiestas Carcaba, E. ; Schneider, A. ; Ostermann, B. ; Danisch, S. ; von Kaisenberg, C. ; Rybniker, J. ; Hammerschmidt, W. ; Zeidler, R. ; Stripecke, R.
Fully human herpesvirus-specific neutralizing IgG antibodies generated by EBV immortalization of splenocytes-derived from immunized humanized Mice.Giehler, F. ; Ostertag, M.S. ; Sommermann, T. ; Weidl, D. ; Sterz, K. ; Kutz, H. ; Moosmann, A. ; Feller, S.M. ; Geerlof, A. ; Biesinger, B. ; Popowicz, G.M. ; Kirchmair, J. ; Kieser, A.
Epstein-Barr virus-driven B cell lymphoma mediated by a direct LMP1-TRAF6 complex.Rambold, U. ; Sperling, S. ; Chew, Z. ; Wang, Y. ; Steer, B. ; Zeller, K. ; Strobl, L.J. ; Zimber-Strobl, U. ; Adler, H.
A mouse model to study the pathogenesis of γ-herpesviral infections in germinal center B cells.Rössler, J. ; Pich, D. ; Krähling, V. ; Becker, S. ; Keppler, O.T. ; Zeidler, R. ; Hammerschmidt, W.
SARS-CoV-2 and Epstein-Barr Virus-like particles associate and fuse with extracellular vesicles in virus neutralization tests.Einer, C. ; Munk, D.E. ; Park, E. ; Akdogan, B. ; Nagel, J. ; Lichtmannegger, J. ; Eberhagen, C. ; Rieder, T. ; Vendelbo, M.H. ; Michalke, B. ; Wimmer, R. ; Blutke, A. ; Feuchtinger, A. ; Dershwitz, P. ; DiSpirito, A.M. ; Islam, T. ; Castro, R.E. ; Min, B.K. ; Kim, T.W. ; Choi, S. ; Kim, D. ; Jung, C. ; Lee, H. ; Park, D. ; Im, W. ; Eun, S.Y. ; Cho, Y.H. ; Semrau, J.D. ; Rodrigues, C.M.P. ; Hohenester, S. ; Damgaard Sandahl, T. ; DiSpirito, A.A. ; Zischka, H.
ARBM101 (Methanobactin SB2) drains excess liver copper via biliary excretion in Wilson's disease rats.Amador, S. ; Beuschlein, F. ; Chauhan, V.P. ; Favier, J. ; Gil, D. ; Greenwood, P. ; de Krijger, R.R. ; Kroiss, M. ; Ortuño-Miquel, S. ; Patocs, A. ; Stell, A. ; Walch, A.K.
Deep learning approaches applied to image classification of renal tumors: A systematic review.Liu, N. ; Gujrati, V. ; Fuenzalida Werner, J.P. ; Mishra, K. ; Anzenhofer,P. ; Stiel, A.-C. ; Mettenleiter, G. ; Feuchtinger, A. ; Walch, A.K. ; Ntziachristos, V.
Bacterial outer membrane vesicles as cationic dye carriers for optoacoustics-guided phototherapy of cancer.Skerniskyte, J. ; Mulet, C. ; André, A.C. ; Anderson, M.C. ; Injarabian, L. ; Buck, A. ; Prade, V.M. ; Sansonetti, P.J. ; Reibel-Foisset, S. ; Walch, A.K. ; Lebel, M. ; Lykkesfeldt, J. ; Marteyn, B.S.
Ascorbate deficiency increases progression of shigellosis in guinea pigs and mice infection models.Han, L. ; Haefner, V. ; Yu, Y. ; Han, B. ; Ren, H. ; Irmler, M. ; Beckers, J. ; Liu, Q. ; Feuchtinger, A. ; Yildirim, A.Ö. ; Adler, H. ; Stöger, T.
Nanoparticle-exposure-triggered virus reactivation induces lung emphysema in mice.Glueck, O.M. ; Liang, X. ; Badell, I. ; Wratil, P.R. ; Graf, A. ; Krebs, S. ; Blum, H. ; Hellmuth, J.C. ; Scherer, C. ; Hollaus, A. ; Spaeth, P.M. ; Karakoc, B. ; Fuchs, T. ; Zimmermann, J. ; Kauke, T. ; Moosmann, A. ; Keppler, O.T. ; Schneider, C. ; Muenchhoff, M.
Impaired immune responses and prolonged viral replication in lung allograft recipients infected with SARS-CoV-2 in the early phase after transplantation.Wang, J. ; Sun, N. ; Kunzke, T. ; Shen, J. ; Zens, P. ; Prade, V.M. ; Feuchtinger, A. ; Berezowska, S. ; Walch, A.K.
Spatial metabolomics identifies distinct tumor-specific and stroma-specific subtypes in patients with lung squamous cell carcinoma.Steiner, S. ; Fehrer, A. ; Hoheisel, F. ; Schoening, S. ; Aschenbrenner, A. ; Babel, N. ; Bellmann-Strobl, J. ; Finke, C. ; Fluge, Ø. ; Froehlich, L. ; Goebel, A. ; Grande, B. ; Haas, J.P. ; Hohberger, B. ; Jason, L.A. ; Komaroff, A.L. ; Lacerda, E. ; Liebl, M. ; Maier, A. ; Mella, O. ; Nacul, L. ; Paul, F. ; Prusty, B.K. ; Puta, C. ; Riemekasten, G. ; Ries, W. ; Rowe, P.C. ; Sawitzki, B. ; Shoenfeld, Y. ; Schultze, J.L. ; Seifert, M. ; Sepúlveda, N. ; Sotzny, F. ; Stein, E. ; Stingl, M. ; Ufer, F. ; Veauthier, C. ; Westermeier, F. ; Wirth, K. ; Wolfarth, B. ; Zalewski, P. ; Behrends, U. ; Scheibenbogen, C.
Understanding, diagnosing, and treating Myalgic encephalomyelitis/chronic fatigue syndrome – State of the art: Report of the 2nd international meeting at the Charité Fatigue Center.Rosowski, S. ; Remmert, C. ; Marder, M. ; Akishiba, M. ; Bushe, J. ; Feuchtinger, A. ; Platen, A. ; Ussar, S. ; Theis, F.J. ; Wiedenmann, S. ; Meier, M.
Single-cell characterization of neovascularization using hiPSC-derived endothelial cells in a 3D microenvironment.Sigle, M. ; Rohlfing, A.K. ; Kenny, M. ; Scheuermann, S. ; Sun, N. ; Graeßner, U. ; Haug, V. ; Sudmann, J. ; Seitz, C.M. ; Heinzmann, D. ; Schenke-Layland, K. ; Maguire, P.B. ; Walch, A. ; Marzi, J. ; Gawaz, M.P.
Translating genomic tools to Raman spectroscopy analysis enables high-dimensional tissue characterization on molecular resolution.Scheibenbogen, C. ; Bellmann-Strobl, J.T. ; Heindrich, C. ; Wittke, K. ; Stein, E. ; Franke, C. ; Prüss, H. ; Preßler, H. ; Machule, M.L. ; Audebert, H. ; Finke, C. ; Zimmermann, H.G. ; Sawitzki, B. ; Meisel, C. ; Toelle, M. ; Krueger, A. ; Aschenbrenner, A.C. ; Schultze, J.L. ; Beyer, M.D. ; Ralser, M. ; Mülleder, M. ; Sander, L.E. ; Konietschke, F. ; Paul, F. ; Stojanov, S. ; Bruckert, L. ; Hedderich, D.M. ; Knolle, F. ; Riemekasten, G. ; Vehreschild, M.J.G.T. ; Cornely, O.A. ; Behrends, U. ; Burock, S.
Fighting Post-COVID and ME/CFS – development of curative therapies.Sigmund, F. ; Berezin, O. ; Beliakova, S. ; Magerl, B. ; Drawitsch, M. ; Piovesan, A. ; Gonçalves, F. ; Bodea, S.V. ; Winkler, S. ; Bousraou, Z. ; Grosshauser, M. ; Samara, E. ; Pujol-Martí, J. ; Schädler, S. ; So, C. ; Irsen, S. ; Walch, A.K. ; Kofler, F. ; Piraud, M. ; Kornfeld, J. ; Briggman, K. ; Westmeyer, G.G.
Genetically encoded barcodes for correlative volume electron microscopy.Esser, K. ; Cheng, X. ; Wettengel, J.M. ; Lucifora, J. ; Hansen-Palmus, L. ; Austen, K. ; Roca Suarez, A.A. ; Heintz, S. ; Testoni, B. ; Nebioglu, F. ; Pham, M.T. ; Yang, S. ; Zernecke, A. ; Wohlleber, D. ; Ringelhan, M. ; Broxtermann, M. ; Hartmann, D. ; Hüser, N. ; Mergner, J. ; Pichlmair, A. ; Thasler, W.E. ; Heikenwälder, M. ; Gasteiger, G. ; Blutke, A. ; Walch, A.K. ; Knolle, P.A. ; Bartenschlager, R. ; Protzer, U.
Hepatitis B virus targets lipid transport pathways to infect hepatocytes.Reguraman, N. ; Hassani, A. ; Philip, P.S. ; Pich, D. ; Hammerschmidt, W. ; Khan, G.
Assessing the efficacy of VLP-based Vaccine against Epstein-Barr Virus using a rabbit model.Gong, S. ; Sun, N. ; Meyer, L.S. ; Tetti, M. ; Koupourtidou, C. ; Krebs, S. ; Masserdotti, G. ; Blum, H. ; Rainey, W.E. ; Reincke, M. ; Walch, A.K. ; Williams, T.A.
Primary aldosteronism: Spatial multi-omics mapping of genotype-dependent heterogeneity and tumor expansion of aldosterone-producing adenomas.Shen, J. ; Sun, N. ; Wang, J. ; Zens, P. ; Kunzke, T. ; Buck, A. ; Prade, V.M. ; Wang, Q. ; Feuchtinger, A. ; Hu, R. ; Berezowska, S. ; Walch, A.K.
Patterns of carbon-bound exogenous compounds impact disease pathophysiology in lung cancer subtypes in different ways.Wang, Q. ; Sun, N. ; Meixner, R. ; Le Gleut, R. ; Kunzke, T. ; Feuchtinger, A. ; Wang, J. ; Shen, J. ; Kircher, S. ; Dischinger, U. ; Weigand, I. ; Beuschlein, F. ; Fassnacht, M. ; Kroiss, M. ; Walch, A.K.
Metabolic heterogeneity in adrenocortical carcinoma impacts patient outcomes.Sachs, S. ; Götz, A. ; Finan, B. ; Feuchtinger, A. ; DiMarchi, R.D. ; Döring, Y. ; Weber, C. ; Tschöp, M.H. ; Müller, T.D. ; Hofmann, S.M.
GIP receptor agonism improves dyslipidemia and atherosclerosis independently of body weight loss in preclinical mouse model for cardio-metabolic disease.Pena-Francesch, M. ; Vanoaica, L.D. ; Zhu, G.F. ; Stumpe, M. ; Sankar, D.S. ; Nowag, H. ; Valencia-Camargo, A.D. ; Hammerschmidt, W. ; Dengjel, J. ; Ligeon, L.A. ; Münz, C.
The autophagy machinery interacts with EBV capsids during viral envelope release.Alfaro, A.J. ; Dittner, C. ; Becker, J. ; Loft, A. ; Mhamane, A. ; Maida, A. ; Georgiadi, A. ; Tsokanos, F.-F. ; Klepac, K. ; Molocea, C.-E. ; El-Merahbi, R. ; Motzler, K. ; Geppert, J. ; Karikari, R.A. ; Szendrödi, J. ; Feuchtinger, A. ; Hofmann, S.M. ; Karaca, S. ; Urlaub, H. ; Berriel Diaz, M. ; Melchior, F. ; Herzig, S.
Fasting-sensitive SUMO-switch on Prox1 controls hepatic cholesterol metabolism.Klontzas, M.E. ; Koltsakis, E. ; Kalarakis, G. ; Trpkov, K. ; Papathomas, T. ; Sun, N. ; Walch, A.K. ; Karantanas, A.H. ; Tzortzakakis, A.
A pilot radiometabolomics integration study for the characterization of renal oncocytic neoplasia.Langenmayer, M.C. ; Luelf-Averhoff, A.T. ; Marr, L. ; Jany, S. ; Freudenstein, A. ; Adam-Neumair, S. ; Tscherne, A. ; Fux, R. ; Rojas, J.J. ; Blutke, A. ; Sutter, G. ; Volz, A.
Newly designed poxviral promoters to improve immunogenicity and efficacy of MVA-NP candidate vaccines against lethal influenza virus infection in mice.Mateska, I. ; Witt, A. ; Hagag, E. ; Sinha, A. ; Yilmaz, C. ; Thanou, E. ; Sun, N. ; Kolliniati, O. ; Patschin, M. ; Abdelmegeed, H. ; Henneicke, H. ; Kanczkowski, W. ; Wielockx, B. ; Tsatsanis, C. ; Dahl, A. ; Walch, A.K. ; Li, K.W. ; Peitzsch, M. ; Chavakis, T. ; Alexaki, V.I.
Succinate mediates inflammation-induced adrenocortical dysfunction.Pisula, J.I. ; Datta, R.R. ; Valdez, L.B. ; Avemarg, J.R. ; Jung, J.O. ; Plum, P. ; Löser, H. ; Lohneis, P. ; Meuschke, M. ; Dos Santos, D.P. ; Gebauer, F. ; Quaas, A. ; Walch, A.K. ; Bruns, C.J. ; Lawonn, K. ; Popp, F.C. ; Bozek, K.
Predicting the HER2 status in oesophageal cancer from tissue microarrays using convolutional neural networks.Murakami, M. ; Sun, N. ; Li, F. ; Feuchtinger, A. ; Gomez-Sanchez, C. ; Fassnacht, M. ; Reincke, M. ; Bancos, I. ; Walch, A.K. ; Kroiss, M. ; Beuschlein, F.
In situ metabolomics of cortisol-producing adenomas.Keppler-Hafkemeyer, A. ; Greil, C. ; Wratil, P.R. ; Shoumariyeh, K. ; Stern, M. ; Hafkemeyer, A. ; Ashok, D. ; Hollaus, A. ; Lupoli, G. ; Priller, A. ; Bischof, M.L. ; Ihorst, G. ; Engelhardt, M. ; Marks, R. ; Finke, J. ; Bertrand, H. ; Dächert, C. ; Muenchhoff, M. ; Badell, I. ; Emmerich, F. ; Halder, H. ; Spaeth, P.M. ; Knolle, P.A. ; Protzer, U. ; von Bergwelt-Baildon, M. ; Duyster, J. ; Hartmann, T.N. ; Moosmann, A. ; Keppler, O.T.
Potent high-avidity neutralizing antibodies and T cell responses after COVID-19 vaccination in individuals with B cell lymphoma and multiple myeloma.Erlmeier, F. ; Sun, N. ; Shen, J. ; Feuchtinger, A. ; Buck, A. ; Prade, V.M. ; Kunzke, T. ; Schraml, P. ; Moch, H. ; Autenrieth, M. ; Weichert, W. ; Hartmann, A. ; Walch, A.K.
MALDI mass spectrometry imaging-Diagnostic pathways and metabolites for renal tumor entities.Xue, B. ; von Heyking, K. ; Gassmann, H. ; Poorebrahim, M. ; Thiede, M. ; Schober, K. ; Mautner, J. ; Hauer, J. ; Ruland, J. ; Busch, D.H. ; Thiel, U. ; Burdach, S.E.G.
T cells directed against the metastatic driver chondromodulin-1 in ewing sarcoma: Comparative engineering with CRISPR/Cas9 vs. retroviral gene transfer for adoptive transfer.Buck, A. ; Prade, V.M. ; Kunzke, T. ; Erben, R.G. ; Walch, A.K.
Spatial metabolomics reveals upregulation of several pyrophosphate-producing pathways in cortical bone of Hyp mice.Nückel, J. ; Planatscher, E. ; Mohr, A.W. ; Deichl, K. ; Mijočević, H. ; Feuerherd, M. ; Wolff, L.S. ; Erber, J. ; Schneider, J. ; Quante, M. ; Winter, C. ; Ruland, J. ; Hapfelmeier, A. ; Hammerschmidt, W. ; Moosmann, A. ; Protzer, U. ; Behrends, U. ; Mautner, J.
Association between IgG responses against the nucleocapsid proteins of alphacoronaviruses and COVID-19 severity.Zeller, T. ; Lutz, S. ; Munnich, I.A. ; Windisch, R. ; Hilger, P. ; Herold, T. ; Tahiri, N. ; Banck, J.C. ; Weigert, O. ; Moosmann, A. ; von Bergwelt-Baildon, M. ; Bruns, H. ; Wichmann, C. ; Valerius, T. ; Schewe, D.M. ; Peipp, M. ; Roesner, T. ; Humpe, A. ; Kellner, C.
Dual checkpoint blockade of CD47 and LILRB1 enhances CD20 antibody-dependent phagocytosis of lymphoma cells by macrophages.Rössler, J. ; Pich, D. ; Albanese, M. ; Wratil, P.R. ; Krähling, V. ; Hellmuth, J.C. ; Scherer, C. ; von Bergwelt-Baildon, M. ; Becker, S. ; Keppler, O.T. ; Brisson, A. ; Zeidler, R. ; Hammerschmidt, W.
Quantitation of SARS-CoV-2 neutralizing antibodies with a virus-free, authentic test.Koch, J. ; Schober, S.J. ; Hindupur, S.V. ; Klein, F.G. ; Mantwill, K. ; Ehrenfeld, M. ; Schillinger, U. ; Hohnecker, T. ; Qi, P. ; Steiger, K. ; Aichler, M. ; Gschwend, J.E. ; Nawroth, R. ; Holm, P.S.
Targeting the Retinoblastoma/E2F repressive complex by CDK4/6 inhibitors amplifies oncolytic potency of an oncolytic adenovirus.Kuhn, L. ; Valentin, S. ; Stojanovic, K. ; Strobl, D.C. ; Babushku, T. ; Wang, Y. ; Rambold, U. ; Scheffler, L. ; Grath, S. ; John-Robbert, D. ; Blum, H. ; Feuchtinger, A. ; Blutke, A. ; Weih, F. ; Kitamura, D. ; Rad, R. ; Strobl, L.J. ; Zimber-Strobl, U.
RelB contributes to the survival, migration and lymphomagenesis of B cells with constitutively active CD40 signaling.Albanese, M. ; Tagawa, T. ; Hammerschmidt, W.
Strategies of Epstein-Barr virus to evade innate antiviral immunity of its human host.Hiepp, L. ; Mayr, D. ; Gärtner, K. ; Schmoeckel, E. ; Klauschen, F. ; Burges, A. ; Mahner, S. ; Zeidler, R. ; Czogalla, B.
Carbonic anhydrase XII as biomarker and therapeutic target in ovarian carcinomas.Beer, S. ; Wange, L.E. ; Zhang, X. ; Kuklik-Roos, C. ; Enard, W. ; Hammerschmidt, W. ; Scialdone, A. ; Kempkes, B.
EBNA2-EBF1 complexes promote MYC expression and metabolic processes driving S-phase progression of Epstein-Barr virus-infected B cells.Maity-Kumar, G. ; Ständer, L. ; de Angelis, M. ; Lee, S. ; Molenaar, A. ; Becker, L. ; Garrett, L. ; Amarie, O.V. ; Hölter, S.M. ; Wurst, W. ; Fuchs, H. ; Feuchtinger, A. ; Gailus-Durner, V. ; García-Cáceres, C. ; Othman, A.E. ; Brockmann, C. ; Schöffling, V.I. ; Beiser, K. ; Krude, H. ; Mroz, P.A. ; Hofmann, S.M. ; Tuckermann, J. ; DiMarchi, R.D. ; Hrabě de Angelis, M. ; Tschöp, M.H. ; Pfluger, P.T. ; Müller, T.D.
Validation of Mct8/Oatp1c1 dKO mice as a model organism for the Allan-Herndon-Dudley Syndrome.Kedor, C. ; Freitag, H. ; Meyer-Arndt, L. ; Wittke, K. ; Hanitsch, L.G. ; Zöller, T. ; Steinbeis, F. ; Haffke, M. ; Rudolf, G. ; Heidecker, B. ; Bobbert, T. ; Spranger, J. ; Volk, H.D. ; Skurk, C. ; Konietschke, F. ; Paul, F. ; Behrends, U. ; Bellmann-Strobl, J. ; Scheibenbogen, C.
A prospective observational study of post-COVID-19 chronic fatigue syndrome following the first pandemic wave in Germany and biomarkers associated with symptom severity.Kedor, C. ; Freitag, H. ; Meyer-Arndt, L. ; Wittke, K. ; Hanitsch, L.G. ; Zöller, T. ; Steinbeis, F. ; Haffke, M. ; Rudolf, G. ; Heidecker, B. ; Bobbert, T. ; Spranger, J. ; Volk, H.D. ; Skurk, C. ; Konietschke, F. ; Paul, F. ; Behrends, U. ; Bellmann-Strobl, J. ; Scheibenbogen, C.
Author Correction: A prospective observational study of post-COVID-19 chronic fatigue syndrome following the first pandemic wave in Germany and biomarkers associated with symptom severity (Nature Communications, (2022), 13, 1, (5104), 10.1038/s41467-022-32507-6).Ackermann, M. ; Kamp, J.C. ; Werlein, C. ; Walsh, C.L. ; Stark, H. ; Prade, V.M. ; Surabattula, R. ; Wagner, W.L. ; Disney, C. ; Bodey, A.J. ; Illig, T. ; Leeming, D.J. ; Karsdal, M.A. ; Tzankov, A. ; Boor, P. ; Kühnel, M.P. ; Länger, F.P. ; Verleden, S.E. ; Kvasnicka, H.M. ; Kreipe, H.H. ; Haverich, A. ; Black, S.M. ; Walch, A. ; Tafforeau, P. ; Lee, P.D. ; Hoeper, M.M. ; Welte, T. ; Seeliger, B. ; David, S.P. ; Schuppan, D. ; Mentzer, S.J. ; Jonigk, D.D.
The fatal trajectory of pulmonary COVID-19 is driven by lobular ischemia and fibrotic remodelling.Lombardo, E. ; Hess J. ; Kurz, C. ; Riboldi, M. ; Marschner, S. ; Baumeister, P. ; Lauber, K. ; Pflugradt, U. ; Walch, A.K. ; Canis, M. ; Klauschen, F. ; Zitzelsberger, H. ; Belka, C. ; Landry, G. ; Unger, K.
DeepClassPathway: Molecular pathway aware classification using explainable deep learning.Hess J. ; Unger, K. ; Maihoefer, C. ; Schuettrumpf, L. ; Weber, P. ; Marschner, S. ; Wintergerst, L. ; Pflugradt, U. ; Baumeister, P. ; Walch, A.K. ; Woischke, C. ; Kirchner, T. ; Werner, M. ; Soerensen, K. ; Baumann, M. ; Tinhofer, I. ; Combs, S.E. ; Debus, J. ; Schaefer, H. ; Krause, M. ; Linge, A. ; von der Gruen, J. ; Stuschke, M. ; Zips, D. ; Canis, M. ; Lauber, K. ; Ganswindt, U. ; Henke, M. ; Zitzelsberger, H. ; Belka, C.
Integration of p16/HPV DNA status with a 24-miRNA-defined molecular phenotype improves clinically relevant stratification of head and neck cancer patients.Kreutzer, L. ; Weber, P. ; Heider, T. ; Heikenwaelder, M. ; Riedl, T. ; Baumeister, P. ; Klauschen, F. ; Belka, C. ; Walch, A.K. ; Zitzelsberger, H. ; Hess J. ; Unger, K.
Simultaneous metabolite MALDI-MSI, whole exome and transcriptome analysis from formalin-fixed paraffin-embedded tissue sections.Hui, B. ; Lu, C. ; Li, H. ; Hao, X. ; Liu, H. ; Zhuo, D. ; Wang, Q. ; Li, Z. ; Liu, L. ; Wang, X. ; Gu, Y. ; Tang, W.
Inhibition of APOE potentiates immune checkpoint therapy for cancer.Kellner, M. ; von Neubeck, B. ; Czogalla, B. ; Feederle, R. ; Vick, B. ; Jeremias, I. ; Zeidler, R.
A novel anti-CD73 antibody that selectively inhibits membrane 2 CD73 shows antitumor activity and induces tumor immune escape.Mentz, M. ; Keay, W. ; Strobl, C.D. ; Antoniolli, M. ; Adolph, L. ; Heide, M. ; Lechner, A. ; Haebe, S. ; Osterode, E. ; Kridel, R. ; Ziegenhain, C. ; Wange, L.E. ; Hildebrand, J.A. ; Shree, T. ; Silkenstedt, E. ; Staiger, A.M. ; Ott, G. ; Horn, H. ; Szczepanowski, M. ; Richter, J. ; Levy, R. ; Rosenwald, A. ; Enard, W. ; Zimber-Strobl, U. ; von Bergwelt-Baildon, M. ; Hiddemann, W. ; Klapper, W. ; Schmidt-Supprian, M. ; Rudelius, M. ; Bararia, D. ; Passerini, V. ; Weigert, O.
PARP14 is a novel target in STAT6 mutant follicular lymphoma.Erlmeier, F. ; Sun, N. ; Shen, J. ; Feuchtinger, A. ; Buck, A. ; Prade, V.M. ; Kunzke, T. ; Schraml, P. ; Moch, H. ; Autenrieth, M. ; Weichert, W. ; Hartmann, A. ; Walch, A.K.
MALDI mass spectrometry imaging—prognostic pathways and metabolites for renal cell carcinomas.Wang, Q. ; Sun, N. ; Kunzke, T. ; Buck, A. ; Shen, J. ; Prade, V.M. ; Stöckl, B. ; Wang, J. ; Feuchtinger, A. ; Walch, A.K.
A simple preparation step to remove excess liquid lipids in white adipose tissue enabling improved detection of metabolites via MALDI-FTICR imaging MS.Ebert, K. ; Haffner, I. ; Zwingenberger, G. ; Keller, S. ; Raimúndez, E. ; Geffers, R. ; Wirtz, R. ; Barbaria, E. ; Hollerieth, V. ; Arnold, R. ; Walch, A.K. ; Hasenauer, J. ; Maier, D. ; Lordick, F. ; Luber, B.
Combining gene expression analysis of gastric cancer cell lines and tumor specimens to identify biomarkers for anti-HER therapies-the role of HAS2, SHB and HBEGF.Ravi, V.M. ; Will, P. ; Kueckelhaus, J. ; Sun, N. ; Joseph, K. ; Salié, H. ; Vollmer, L. ; Kuliesiute, U. ; von Ehr, J. ; Benotmane, J.K. ; Neidert, N. ; Follo, M. ; Scherer, F. ; Goeldner, J.M. ; Behringer, S.P. ; Franco, P. ; Khiat, M. ; Zhang, J. ; Hofmann, U.G. ; Fung, C. ; Ricklefs, F.L. ; Lamszus, K. ; Boerries, M. ; Ku, M.C. ; Beck, J. ; Sankowski, R. ; Schwabenland, M. ; Prinz, M. ; Schüller, U. ; Killmer, S. ; Bengsch, B. ; Walch, A.K. ; Delev, D. ; Schnell, O. ; Heiland, D.H.
Spatially resolved multi-omics deciphers bidirectional tumor-host interdependence in glioblastoma.Tang, W. ; Zhou, Y. ; Zhao, H. ; Sun, G. ; Rong, D. ; Li, Z. ; Hu, M. ; Han, L.F. ; He, X. ; Zhao, S. ; Chen, X. ; Yuan, H. ; Chen, S. ; Wang, Q. ; Gu, J. ; Wang, X. ; Song, J.
A 3D multi-modal intelligent intervention system using electromagnetic navigation for real-time positioning and ultrasound images: A prospective randomized controlled trial.Shen, J. ; Sun, N. ; Zens, P. ; Kunzke, T. ; Buck, A. ; Prade, V.M. ; Wang, J. ; Wang, Q. ; Hu, R. ; Feuchtinger, A. ; Berezowska, S. ; Walch, A.K.
Spatial metabolomics for evaluating response to neoadjuvant therapy in non-small cell lung cancer patients.Testa, C. ; Papini, A.M. ; Zeidler, R. ; Vullo, D. ; Carta, F. ; Supuran, C.T. ; Rovero, P.
First studies on tumor associated carbonic anhydrases IX and XII monoclonal antibodies conjugated to small molecule inhibitors.Prade, V.M. ; Sun, N. ; Shen, J. ; Feuchtinger, A. ; Kunzke, T. ; Buck, A. ; Schraml, P. ; Moch, H. ; Schwamborn, K. ; Autenrieth, M. ; Gschwend, J.E. ; Erlmeier, F. ; Hartmann, A. ; Walch, A.K.
The synergism of spatial metabolomics and morphometry improves machine learning-based renal tumour subtype classification.Paul, T. ; Ledderose, S. ; Bartsch, H. ; Sun, N. ; Soliman, S. ; Märkl, B. ; Ruf, V. ; Herms, J. ; Stern, M. ; Keppler, O.T. ; Delbridge, C. ; Müller, S. ; Piontek, G. ; Kimoto, Y.S. ; Schreiber, F. ; Williams, T.A. ; Neumann, J. ; Knösel, T. ; Schulz, H. ; Spallek, R. ; Graw, M. ; Kirchner, T. ; Walch, A.K. ; Rudelius, M.
Adrenal tropism of SARS-CoV-2 and adrenal findings in a post-mortem case series of patients with severe fatal COVID-19.Kogan, P.S. ; Wirth, F. ; Tomar, A. ; Darr, J. ; Teperino, R. ; Lahm, H. ; Dreßen, M. ; Puluca, N. ; Zhang, Z. ; Neb, I. ; Beck, N. ; Luzius, T. ; de la Osa de la Rosa, L. ; Gärtner, K. ; Hüls, C. ; Zeidler, R. ; Ramanujam, D. ; Engelhardt, S. ; Wenk, C. ; Holdt, L.M. ; Mononen, M. ; Sahara, M. ; Cleuziou, J. ; Hörer, J. ; Lange, R. ; Krane, M. ; Doppler, S.A.
Uncovering the molecular identity of cardiosphere-derived cells (CDCs) by single-cell RNA sequencing.Loft, A. ; Schmidt, S.F. ; Caratti, G. ; Stifel, U. ; Havelund, J.F. ; Sekar, R. ; Kwon, Y. ; Sulaj, A. ; Chow, K.K. ; Alfaro, A.J. ; Schwarzmayr, T. ; Rittig, N. ; Svart, M. ; Tsokanos, F.-F. ; Maida, A. ; Blutke, A. ; Feuchtinger, A. ; Møller, N. ; Blüher, M. ; Nawroth, P. ; Szendrödi, J. ; Færgeman, N.J. ; Zeigerer, A. ; Tuckermann, J. ; Herzig, S.
A macrophage-hepatocyte glucocorticoid receptor axis coordinates fasting ketogenesis.Wang, J. ; Kunzke, T. ; Prade, V.M. ; Shen, J. ; Buck, A. ; Feuchtinger, A. ; Haffner, I. ; Luber, B. ; Liu, D.H.W. ; Langer, R. ; Lordick, F. ; Sun, N. ; Walch, A.K.
Spatial metabolomics identifies distinct tumor-specific subtypes in gastric cancer patients.Sato, S. ; Dyar, K.A. ; Treebak, J.T. ; Jepsen, S.L. ; Ehrlich, A.M. ; Ashcroft, S.P. ; Trost, K. ; Kunzke, T. ; Prade, V.M. ; Small, L. ; Basse, A.L. ; Schönke, M. ; Chen, S. ; Samad, M. ; Baldi, P. ; Barrès, R. ; Walch, A.K. ; Moritz, T. ; Holst, J.J. ; Lutter, D. ; Zierath, J.R. ; Sassone-Corsi, P.
Atlas of exercise metabolism reveals time-dependent signatures of metabolic homeostasis.Weber, P. ; Künstner, A. ; Hess J. ; Unger, K. ; Marschner, S. ; Idel, C. ; Ribbat-Idel, J. ; Walz, C. ; Rietzler, S. ; Valeanu, L. ; Herkommer, T. ; Kreutzer, L. ; Klymenko, O. ; Kirchner, T. ; Ganswindt, U. ; Walch, A.K. ; Sterr, M. ; Lickert, H. ; Canis, M. ; Rades, D. ; Perner, S. ; Berriel Diaz, M. ; Herzig, S. ; Wollenberg, B. ; Busch, H. ; Zitzelsberger, H.
Therapy-related transcriptional subtypes in matched primary and recurrent head and neck cancer.Bernaudat, F. ; Gustems, M. ; Günther, J. ; Oliva, M.F. ; Buschle, A. ; Göbel,C. ; Pagniez, P. ; Lupo, J. ; Signor, L. ; Müller, C.W. ; Morand, P. ; Sattler, M. ; Hammerschmidt, W. ; Petosa, C.
Structural basis of DNA methylation-dependent site selectivity of the Epstein-Barr virus lytic switch protein ZEBRA/Zta/BZLF1.Buck, A. ; Prade, V.M. ; Kunzke, T. ; Feuchtinger, A. ; Kröll, D. ; Feith, M. ; Dislich, B. ; Balluff, B. ; Langer, R. ; Walch, A.K.
Metabolic tumor constitution is superior to tumor regression grading for evaluating response to neoadjuvant therapy of esophageal adenocarcinoma patients.Liu, N. ; O'Connor, P. ; Gujrati, V. ; Gorpas, D. ; Glasl, S. ; Blutke, A. ; Walch, A.K. ; Kleigrewe, K. ; Sattler, M. ; Plettenburg, O. ; Ntziachristos, V.
Facile synthesis of a croconaine-based nanoformulation for optoacoustic imaging and photothermal therapy.Westhoff Smith, D. ; Chakravorty, A. ; Hayes, M. ; Hammerschmidt, W. ; Sugden, B.
The Epstein-Barr virus oncogene EBNA1 suppresses natural killer cell responses and apoptosis early after infection of peripheral B cells.Albanese, M. ; Chen, Y.-F. A. ; Hüls, C. ; Gärtner, K. ; Tagawa, T. ; Mejias-Perez, E. ; Keppler, O.T. ; Göbel,C. ; Zeidler, R. ; Shein, M. ; Schütz, A.K. ; Hammerschmidt, W.
MicroRNAs are minor constituents of extracellular vesicles that are rarely delivered to target cells.Li, Z. ; Sun, G. ; Sun, G. ; Cheng, Y. ; Wu, L. ; Wang, Q. ; Lv, C. ; Zhou, Y. ; Xia, Y. ; Tang, W.
Various uses of PD1/PD-L1 inhibitor in oncology: Opportunities and challenges.Cirac, A. ; Poirey, R. ; Dieckmeyer, M. ; Witter, K. ; Delecluse, H.J. ; Behrends, U. ; Mautner, J.
Immunoinformatic analysis reveals antigenic heterogeneity of Epstein-Barr virus is immune-driven.Haebe, S. ; Keay, W. ; Alig, S. ; Mohr, A.-W. ; Martin, L.K. ; Heide, M. ; Secci, R. ; Krebs, S. ; Blum, H. ; Moosmann, A. ; Louissaint, A. ; Weinstock, D.M. ; Thoene, S. ; von Bergwelt-Baildon, M. ; Ruland, J. ; Bararia, D. ; Weigert, O.
The molecular ontogeny of follicular lymphoma: Gene mutations succeeding the BCL2 translocation define common precursor cells.Sun, N. ; Trajkovic-Arsic, M. ; Li, F. ; Wu, Y. ; Münch, C. ; Kunzke, T. ; Feuchtinger, A. ; Steiger, K. ; Schlitter, A.M. ; Weichert, W. ; Esposito, I. ; Siveke, J.T. ; Walch, A.K.
Native glycan fragments detected by MALDI mass spectrometry imaging are independent prognostic factors in pancreatic ductal adenocarcinoma.Zhao, L. ; Chen, F. ; Quitt, O. ; Festag, M. ; Ringelhan, M. ; Wisskirchen, K. ; Festag, J. ; Yakovleva, L. ; Sureau, C. ; Bohne, F. ; Aichler, M. ; Bruss, V. ; Shevtsov, M. ; van de Klundert, M. ; Momburg, F. ; Möhl, B.S. ; Protzer, U.
Hepatitis B virus envelope proteins can serve as therapeutic targets embedded in the host cell plasma membrane.Yuan, S. ; Liao, G. ; Zhang, M. ; Zhu, Y. ; Xiao, W. ; Wang, K. ; Li, C. ; Jia, C. ; Sun, N. ; Walch, A.K. ; Gao, D. ; Xu, P. ; Deng, Q. ; Zhang, J. ; Wang, H. ; Hu, R.
Multiomics interrogation into HBV (Hepatitis B virus)-host interaction reveals novel coding potential in human genome, and identifies canonical and non-canonical proteins as host restriction factors against HBV.Burkhardt, R. ; Gora, T. ; Fingerle, A.A. ; Sauter, A.P. ; Meurer, F. ; Gassert, F.T. ; Dobiasch, S. ; Schilling, D. ; Feuchtinger, A. ; Walch, A.K. ; Multhoff, G. ; Herzen, J. ; Noel, P.B. ; Rummeny, E.J. ; Combs, S.E. ; Schmid, T.E. ; Pfeiffer, F. ; Wilkens, J.J.
In-vivo X-ray dark-field computed tomography for the detection of radiation-induced lung damage in mice.Zhang, X. ; Schuhmachers, P. ; Mourao, A. ; Giansanti, P. ; Murer, A. ; Thumann, S. ; Kuklik-Roos, C. ; Beer, S. ; Hauck, S.M. ; Hammerschmidt, W. ; Kuppers, R. ; Kuster, B. ; Raab, M. ; Strebhardt, K. ; Sattler, M. ; Münz, C. ; Kempkes, B.
PLK1-dependent phosphorylation restrains EBNA2 activity and lymphomagenesis in EBV-infected mice.Kunzke, T. ; Prade, V.M. ; Buck, A. ; Sun, N. ; Feuchtinger, A. ; Matzka, M. ; Fernandez, I.E. ; Wuyts, W.A. ; Ackermann, M. ; Jonigk, D. ; Aichler, M. ; Schmid, R.A. ; Eickelberg, O. ; Berezowska, S. ; Walch, A.K.
Patterns of carbon-bound exogenous compounds in lung cancer patients and association with disease pathophysiology.Manet, E. ; Polvèche, H. ; Mure, F. ; Mrozek-Gorska, P. ; Roisné-Hamelin, F. ; Hammerschmidt, W. ; Auboeuf, D. ; Gruffat, H.
Modulation of alternative splicing during early infection of human primary B lymphocytes with Epstein-Barr virus (EBV): A novel function for the viral EBNA-LP protein.Kunzke, T. ; Hölzl, F.T. ; Prade, V.M. ; Buck, A. ; Huber, K. ; Feuchtinger, A. ; Ebert, K. ; Zwingenberger, G. ; Geffers, R. ; Hauck, S.M. ; Haffner, I. ; Luber, B. ; Lordick, F. ; Walch, A.K.
Metabolomic therapy response prediction in pretherapeutic tissue biopsies for trastuzumab in patients with HER2-positive advanced gastric cancer.Aliluev, A. ; Tritschler, S. ; Sterr, M. ; Oppenländer, L. ; Hinterdobler, J. ; Greisle, T. ; Irmler, M. ; Beckers, J. ; Sun, N. ; Walch, A.K. ; Stemmer, K. ; Kindt, A. ; Krumsiek, J. ; Tschöp, M.H. ; Luecken, M. ; Theis, F.J. ; Lickert, H. ; Böttcher, A.
Diet-induced alteration of intestinal stem cell function underlies obesity and prediabetes in mice.Huang, S. ; Blutke, A. ; Feuchtinger, A. ; Klemm, U. ; Zachariah Tom, R. ; Hofmann, S.M. ; Stiel, A.C. ; Ntziachristos, V.
Functional multispectral optoacoustic tomography imaging of hepatic steatosis development in mice.Chhabra, N.F. ; Amend, A.-L. ; Bastidas-Ponce, A. ; Sabrautzki, S. ; Tarquis Medina, M. ; Sachs, S. ; Rubey, M. ; Lorenz-Depiereux, B. ; Feuchtinger, A. ; Bakhti, M. ; Lickert, H. ; Przemeck, G.K.H. ; Hrabě de Angelis, M.
A point mutation in the Pdia6 gene results in loss of pancreatic β-cell identity causing overt diabetes.Maier, J.P. ; Kueckelhaus, J. ; Behringer, S.P. ; Garrelfs, N. ; Will, P. ; Sun, N. ; von Ehr, J. ; Goeldner, J.M. ; Pfeifer, D. ; Follo, M. ; Hannibal, L. ; Walch, A.K. ; Hofmann, U.G. ; Beck, J. ; Heiland, D.H. ; Schnell, O.
Inhibition of metabotropic glutamate receptor III facilitates sensitization to alkylating chemotherapeutics in glioblastoma.Böttcher, K. ; Braunschmidt, K. ; Hirth, G. ; Schärich, K. ; Klassert, T.E. ; Stock, M. ; Sorgatz, J. ; Fischer-Burkart, S. ; Ullrich, S. ; Frankenberger, S. ; Kritsch, D. ; Kosan, C. ; Küppers, R. ; Strobl, L.J. ; Slevogt, H. ; Zimber-Strobl, U. ; Jungnickel, B.
Context-dependent regulation of immunoglobulin mutagenesis by p53.Loft, A. ; Alfaro, A.J. ; Schmidt, S.F. ; Pedersen, F.B. ; Terkelsen, M.K. ; Puglia, M. ; Chow, K.K. ; Feuchtinger, A. ; Troullinaki, M. ; Maida, A. ; Wolff, G. ; Sakurai, M. ; Berutti, R. ; Ekim Üstünel, B. ; Nawroth, P.P. ; Ravnskjaer, K. ; Diaz, M.B. ; Blagoev, B. ; Herzig, S.
Liver-fibrosis-activated transcriptional networks govern hepatocyte reprogramming and intra-hepatic communication.Murakami, M. ; Sun, N. ; Greunke, C. ; Feuchtinger, A. ; Kircher, S. ; Deutschbein, T. ; Papathomas, T. ; Bechmann, N. ; Wallace, P.W. ; Peitzsch, M. ; Korpershoek, E. ; Friemel, J. ; Gimenez Roqueplo, A.P. ; Robledo, M. ; Timmers, H.J. ; Canu, L. ; Weber, A. ; de Krijger, R.R. ; Fassnacht, M. ; Knösel, T. ; Kirchner, T. ; Reincke, M. ; Walch, A.K. ; Kroiss, M. ; Beuschlein, F.
Mass spectrometry imaging identifies metabolic patterns associated with malignant potential in pheochromocytoma and paraganglioma.Scheffler, L. ; Feicht, S. ; Babushku, T. ; Kuhn, L. ; Ehrenberg, S. ; Frankenberger, S. ; Lehmann, F.M. ; Hobeika, E. ; Jungnickel, B. ; Baccarini, M. ; Bornkamm, G.W. ; Strobl, L.J. ; Zimber-Strobl, U.
ERK phosphorylation is RAF independent in naïve and activated B cells but RAF dependent in plasma cell differentiation.Klüpfel, J. ; Koros, R.C. ; Dehne, K. ; Ungerer, M. ; Würstle, S. ; Mautner, J. ; Feuerherd, M. ; Protzer, U. ; Hayden, O. ; Elsner, M. ; Seidel, M.
Automated, flow-based chemiluminescence microarray immunoassay for the rapid multiplex detection of IgG antibodies to SARS-CoV-2 in human serum and plasma (CoVRapid CL-MIA).Georgiadi, A. ; Lopez Salazar, V. ; El-Merahbi, R. ; Karikari, R.A. ; Ma, X. ; Mourao, A. ; Klepac, K. ; Bühler, L. ; Alfaro, A.J. ; Kaczmarek, I. ; Linford, A. ; Bosma, M. ; Shilkova, O. ; Ritvos, O. ; Nakamura, N. ; Hirose, S. ; Lassi, M. ; Teperino, R. ; Machado, J. ; Scheideler, M. ; Dietrich, A. ; Geerlof, A. ; Feuchtinger, A. ; Blutke, A. ; Fischer, K. ; Müller, T.D. ; Kessler, K. ; Schöneberg, T. ; Thor, D. ; Hornemann, S. ; Kruse, M. ; Nawroth, P.P. ; Pivovarova-Ramich, O. ; Pfeiffer, A.F.H. ; Sattler, M. ; Blüher, M. ; Herzig, S.
Orphan GPR116 mediates the insulin sensitizing effects of the hepatokine FNDC4 in adipose tissue.Giroud, M. ; Tsokanos, F.-F. ; Caratti, G. ; Kotschi, S. ; Khani, S. ; Jouffe, C. ; Vogl, E.S. ; Irmler, M. ; Glantschnig, C. ; Gil Lozano, M. ; Haß, D. ; Khan, A.A. ; Rios Garcia, M. ; Mattijssen, F. ; Maida, A. ; Tews, D. ; Fischer-Posovszky, P. ; Feuchtinger, A. ; Virtanen, K.A. ; Beckers, J. ; Wabitsch, M. ; Uhlenhaut, N.H. ; Blüher, M. ; Tuckermann, J. ; Scheideler, M. ; Bartelt, A. ; Herzig, S.
HAND2 is a novel obesity-linked adipogenic transcription factor regulated by glucocorticoid signalling.Liu, N. ; Gujrati, V. ; Malekzadeh-Najafabadi, J. ; Werner, J.P,F. ; Klemm, U. ; Tang, L. ; Chen, Z. ; Prakash, J. ; Huang, Y. ; Stiel, A.-C. ; Mettenleiter, G. ; Aichler, M. ; Blutke, A. ; Walch, A.K. ; Kleigrewe, K. ; Razansky, D. ; Sattler, M. ; Ntziachristos, V.
Croconaine-based nanoparticles enable efficient optoacoustic imaging of murine brain tumors.Deng, Y. ; Chatterjee, B. ; Zens, K. ; Zdimerova, H. ; Müller, A. ; Schuhmachers, P. ; Ligeon, L.A. ; Bongiovanni, A. ; Capaul, R. ; Zbinden, A. ; Holler, A. ; Stauss, H.J. ; Hammerschmidt, W. ; Münz, C.
CD27 is required for protective lytic EBV antigen specific CD8+ T cell expansion.Orth, M. ; Albrecht, V. ; Seidl, K. ; Kinzel, L. ; Unger, K. ; Hess J. ; Kreutzer, L. ; Sun, N. ; Stegen, B. ; Nieto, A. ; Maas, J. ; Winssinger, N. ; Friedl, A.A. ; Walch, A.K. ; Belka, C. ; Zitzelsberger, H. ; Niyazi, M. ; Lauber, K.
Inhibition of HSP90 as a strategy to radiosensitize glioblastoma: Targeting the DNA damage response and beyond.Haffner, I. ; Schierle, K. ; Raimúndez, E. ; Geier, B. ; Maier, D. ; Hasenauer, J. ; Luber, B. ; Walch, A.K. ; Kolbe, K. ; Riera Knorrenschild, J. ; Kretzschmar, A. ; Rau, B. ; Fischer von Weikersthal, L. ; Ahlborn, M. ; Siegler, G. ; Fuxius, S. ; Decker, T. ; Wittekind, C. ; Lordick, F.
HER2 expression, test deviations, and their impact on survival in metastatic gastric cancer: Results from the prospective multicenter VARIANZ study.Li, F. ; Gu, J. ; Xin, J. ; Schnelle-Kreis, J. ; Wang, Y. ; Liu, Z. ; Shen, R. ; Michalke, B. ; Abbaszade, G. ; Zimmermann, R.
Characteristics of chemical profile, sources and PAH toxicity of PM2.5 in beijing in autumn-winter transit season with regard to domestic heating, pollution control measures and meteorology.Liu, N. ; O'Connor, P. ; Gujrati, V. ; Gorpas, D. ; Glasl, S. ; Blutke, A. ; Walch, A.K. ; Kleigrewe, K. ; Sattler, M. ; Plettenburg, O. ; Ntziachristos, V.
Facile synthesis of a croconaine-based nanoformulation for optoacoustic imaging and photothermal therapy.Ansarullah ; Jain, C. ; Far, F.F. ; Homberg, S. ; Wißmiller, K. ; von Hahn, F. ; Raducanu, A. ; Schirge, S. ; Sterr, M. ; Bilekova, S. ; Siehler, J. ; Wiener, J. ; Oppenländer, L. ; Morshedi, A. ; Bastidas-Ponce, A. ; Collden, G. ; Irmler, M. ; Beckers, J. ; Feuchtinger, A. ; Grzybek, M. ; Ahlbrecht, C. ; Feederle, R. ; Plettenburg, O. ; Müller, T.D. ; Meier, M. ; Tschöp, M.H. ; Coskun, Ü. ; Lickert, H.
Author Correction: Inceptor counteracts insulin signalling in β-cells to control glycaemia.Stauffer, E. ; Weber, P. ; Heider, T. ; Dalke, C. ; Blutke, A. ; Walch, A.K. ; Burgstaller, G. ; Brix, N. ; Lauber, K. ; Zitzelsberger, H. ; Unger, K. ; Selmansberger, M.
Transcriptomic landscape of radiation-induced murine thyroid proliferative lesions.Yuan, S. ; Liao, G. ; Zhang, M. ; Zhu, Y. ; Wang, K. ; Xiao, W. ; Jia, C. ; Dong, M. ; Sun, N. ; Walch, A.K. ; Xu, P. ; Zhang, J. ; Deng, Q. ; Hu, R.
Translatomic profiling reveals novel self-restricting virus-host interactions during HBV infection.Buschle, A. ; Mrozek-Gorska, P. ; Cernilogar, F.M. ; Ettinger, A. ; Pich, D. ; Krebs, S. ; Mocanu, B. ; Blum, H. ; Schotta, G. ; Straub, T. ; Hammerschmidt, W.
Epstein-Barr virus inactivates the transcriptome and disrupts the chromatin architecture of its host cell in the first phase of lytic reactivation.Kirstein, N. ; Buschle, A. ; Wu, X. ; Krebs, S. ; Blum, H. ; Kremmer, E. ; Vorberg, I.M. ; Hammerschmidt, W. ; Lacroix, L. ; Hyrien, O. ; Audit, B. ; Schepers, A.
Human ORC/MCM density is low in active genes and correlates with replication time but does not delimit initiation zones.Akidil, E. ; Albanese, M. ; Buschle, A. ; Ruhle, A. ; Pich, D. ; Keppler, O.T. ; Hammerschmidt, W.
Highly efficient CRISPR-Cas9-mediated gene knockout in primary human B cells for functional genetic studies of Epstein-Barr virus infection.Lechner, M. ; Engleitner, T. ; Babushku, T. ; Schmidt-Supprian, M. ; Rad, R. ; Strobl, L.J. ; Zimber-Strobl, U.
Notch2-mediated plasticity between marginal zone and follicular B cells.Theobalt, N. ; Hofmann, I. ; Fiedler, S. ; Renner, S. ; Dhom, G. ; Feuchtinger, A. ; Walch, A.K. ; Hrabě de Angelis, M. ; Wolf, E. ; Wanke, R. ; Blutke, A.
Unbiased analysis of obesity related, fat depot specific changes of adipocyte volumes and numbers using light sheet fluorescence microscopy.Bouvet, M. ; Voigt, S. ; Tagawa, T. ; Albanese, M. ; Chen, Y.-F. A. ; Chen, Y. ; Fachko, D.N. ; Pich, D. ; Göbel, C. ; Skalsky, R.L. ; Hammerschmidt, W.
Multiple viral micrornas regulate interferon release and signaling early during infection with epstein-barr virus.Volk, V. ; Theobald, S.J. ; Danisch, S. ; Khailaie, S. ; Kalbarczyk, M. ; Schneider, A. ; Bialek-Waldmann, J. ; Krönke, N. ; Deng, Y. ; Eiz-Vesper, B. ; Dragon, A.C. ; von Kaisenberg, C. ; Lienenklaus, S. ; Bleich, A. ; Keck, J. ; Meyer-Hermann, M. ; Klawonn, F. ; Hammerschmidt, W. ; Delecluse, H.J. ; Münz, C. ; Feuerhake, F. ; Stripecke, R.
PD-1 blockade aggravates Epstein–Barr Virus+ post-transplant lymphoproliferative disorder in humanized mice resulting in central nervous system involvement and CD4+ T cell dysregulations.Ruiz Ojeda, F.J. ; Wang, J. ; Bäcker, T. ; Krueger, M. ; Zamani, S. ; Rosowski, S. ; Gruber, T. ; Onogi, Y. ; Feuchtinger, A. ; Schulz, T.J. ; Fässler, R. ; Müller, T.D. ; García-Cáceres, C. ; Meier, M. ; Blüher, M. ; Ussar, S.
Active integrins regulate white adipose tissue insulin sensitivity and brown fat thermogenesis.Ansarullah ; Jain, C. ; Far, F.F. ; Homberg, S. ; Wissmiller, K. ; Gräfin von Hahn, F. ; Raducanu, A. ; Schirge, S. ; Sterr, M. ; Bilekova, S. ; Siehler, J. ; Wiener, J. ; Oppenländer, L. ; Morshedi, A. ; Bastidas-Ponce, A. ; Collden, G. ; Irmler, M. ; Beckers, J. ; Feuchtinger, A. ; Grzybek, M. ; Ahlbrecht, C. ; Feederle, R. ; Plettenburg, O. ; Müller, T.D. ; Meier, M. ; Tschöp, M.H. ; Coskun, Ü. ; Lickert, H.
Inceptor counteracts insulin signalling in β-cells to control glycaemia.Bühler, L. ; Maida, A. ; Vogl, E.S. ; Georgiadi, A. ; Takacs, A. ; Kluth, O. ; Schürmann, A. ; Feuchtinger, A. ; von Toerne, C. ; Tsokanos, F.-F. ; Klepac, K. ; Wolff, G. ; Sakurai, M. ; Ekim Üstünel, B. ; Nawroth, P.P. ; Herzig, S.
Lipocalin 13 enhances insulin secretion but is dispensable for systemic metabolic control.Zhang, Q. ; Delessa, C.T. ; Augustin, R. ; Bakhti, M. ; Collden, G. ; Drucker, D.J. ; Feuchtinger, A. ; García-Cáceres, C. ; Grandl, G. ; Harger, A. ; Herzig, S. ; Hofmann, S.M. ; Holleman, C.L. ; Jastroch, M. ; Keipert, S. ; Kleinert, M. ; Knerr, P.J. ; Kulaj, K. ; Legutko, B. ; Lickert, H. ; Liu, X. ; Luippold, G. ; Lutter, D. ; Malogajski, E. ; Tarquis Medina, M. ; Mowery, S.A. ; Blutke, A. ; Perez-Tilve, D. ; Salinno, C. ; Sehrer, L. ; DiMarchi, R.D. ; Tschöp, M.H. ; Stemmer, K. ; Finan, B. ; Wolfrum, C. ; Müller, T.D.
The glucose-dependent insulinotropic polypeptide (GIP) regulates body weight and food intake via CNS-GIPR signaling.Schinke, H. ; Heider, T. ; Herkommer, T. ; Simon, F. ; Blancke Soares, A. ; Kranz, G. ; Samaga, D. ; Dajka, L. ; Feuchtinger, A. ; Walch, A.K. ; Valeanu, L. ; Walz, C. ; Kirchner, T. ; Canis, M. ; Baumeister, P. ; Belka, C. ; Maihöfer, C. ; Marschner, S. ; Pflugradt, U. ; Ganswindt, U. ; Hess J. ; Zitzelsberger, H. ; Gires, O.
Digital scoring of EpCAM and slug expression as prognostic markers in head and neck squamous cell carcinomas.Napieralski, R. ; Schricker, G. ; Auer, G. ; Aubele, M. ; Perkins, J. ; Magdolen, V. ; Ulm, K. ; Hamann, M. ; Walch, A.K. ; Weichert, W. ; Kiehle, M. ; Weichert, O.G.
PITX2 DNA-methylation: Predictive versus prognostic value for anthracycline-based chemotherapy in triple-negative breast cancer patients.Karlina, R. ; Lutter, D. ; Miok, V. ; Fischer, D.S. ; Altun, I. ; Schöttl, T. ; Schorpp, K.K. ; Israel, A. ; Cero, C. ; Johnson, J.W. ; Kapser-Fischer, I. ; Böttcher, A. ; Keipert, S. ; Feuchtinger, A. ; Graf, E. ; Strom, T.M. ; Walch, A.K. ; Lickert, H. ; Walzthoeni, T. ; Heinig, M. ; Theis, F.J. ; García-Cáceres, C. ; Cypess, A.M. ; Ussar, S.
Identification and characterization of distinct brown adipocyte subtypes in C57BL/6J mice.Burkhardt, R. ; Gora, T. ; Fingerle, A.A. ; Sauter, A.P. ; Meurer, F. ; Umkehrer, S. ; Von Teuffenbach, M. ; Kampfer, S. ; Schilling, D. ; Feuchtinger, A. ; Walch, A.K. ; Rummeny, E. ; Combs, S.E. ; Schmid, T.E. ; Pfeiffer, F. ; Wilkens, J.J. ; Herzen, J.
Early detection of radiation-induced lung damage with X-ray dark-field radiography in mice.Jakob, C.E.M. ; Borgmann, S. ; Duygu, F. ; Behrends, U. ; Hower, M. ; Merle, U. ; Friedrichs, A. ; Tometten, L. ; Hanses, F. ; Jung, N. ; Rieg, S. ; Wille, K. ; Grüner, B. ; Klinker, H. ; Gersbacher-Runge, N. ; Hellwig, K. ; Eberwein, L. ; Dolff, S. ; Rauschning, D. ; von Bergwelt-Baildon, M. ; Lanznaster, J. ; Strauß, R. ; Trauth, J. ; de With, K. ; Ruethrich, M. ; Lueck, C. ; Nattermann, J. ; Tscharntke, L. ; Pilgram, L. ; Fuhrmann, S. ; Classen, A. ; Stecher, M. ; Schons, M. ; Spinner, C. ; Vehreschild, J.J.
First results of the "Lean European Open Survey on SARS-CoV-2-Infected Patients (LEOSS)".Sammer, M. ; Dombrowsky, A. ; Schauer, J. ; Oleksenko, K. ; Bicher, S. ; Schwarz, B. ; Rudigkeit, S. ; Matejka, N. ; Reindl, J. ; Bartzsch, S. ; Blutke, A. ; Feuchtinger, A. ; Combs, S.E. ; Dollinger, G. ; Schmid, T.E.
Normal tissue response of combined temporal and spatial fractionation in proton minibeam radiation therapy.Fiedler, S. ; Wünnemann, H. ; Hofmann, I. ; Theobalt, N. ; Feuchtinger, A. ; Walch, A.K. ; Schwaiger, J. ; Wanke, R. ; Blutke, A.
A practical guide to unbiased quantitative morphological analyses of the gills of rainbow trout (Oncorhynchus mykiss) in ecotoxicological studies.Wang, Q. ; Yang, L. ; Fan, Y. ; Tang, W. ; Sun, H. ; Xu, Z. ; Zhou, J. ; Zhang, Y. ; Zhu, B. ; Cao, X.
Circ-ZDHHC5 accelerates esophageal squamous cell carcinoma progression in vitro via miR-217/ZEB1 axis.Papathomas, T. ; Tzortzakakis, A. ; Sun, N. ; Erlmeier, F. ; Feuchtinger, A. ; Trpkov, K. ; Bazarova, A. ; Arvanitis, A. ; Wang, W. ; Bozoky, B. ; Kokaraki, G. ; Axelsson, R. ; Walch, A.K.
In situ metabolomics expands the spectrum of renal tumours positive on 99mTc-sestamibi single photon emission computed tomography/computed tomography examination.Vohra, T. ; Kemter, E. ; Sun, N. ; Dobenecker, B. ; Hinrichs, A. ; Burrello, J. ; Gomez-Sanchez, E.P. ; Gomez-Sanchez, C.E. ; Wang, J. ; Kinker, I.S. ; Teupser, D. ; Fischer, K. ; Schnieke, A. ; Peitzsch, M. ; Eisenhofer, G. ; Walch, A.K. ; Reincke, M. ; Wolf, E. ; Williams, T.A.
Effect of dietary sodium modulation on pig adrenal steroidogenesis and transcriptome profiles.Wu, F. ; Cheng, Y. ; Wu, L. ; Zhang, W. ; Zheng, W. ; Wang, Q. ; Cao, H. ; Pan, X. ; Tang, W.
Emerging landscapes of tumor immunity and metabolism.Zettler, S. ; Renner, S. ; Kemter, E. ; Hinrichs, A. ; Klymiuk, N. ; Backman, M. ; Riedel, E.O. ; Mueller, C. ; Streckel, E. ; Braun-Reichhart, C. ; Martins, A.S. ; Kurome, M. ; Keßler, B. ; Zakhartchenko, V. ; Flenkenthaler, F. ; Arnold, G.J. ; Fröhlich, T. ; Blum, H. ; Blutke, A. ; Wanke, R. ; Wolf, E.
A decade of experience with genetically tailored pig models for diabetes and metabolic research.Liu, W.-H. ; Mrozek-Gorska, P. ; Wirth, A.-K. ; Herold, T. ; Schwarzkopf, L. ; Pich, D. ; Völse, K. ; Melo-Narváez, C. ; Carlet, M. ; Hammerschmidt, W. ; Jeremias, I.
Inducible transgene expression in PDX models in vivo identifies KLF4 as a therapeutic target for B-ALL.Chhabra, N.F. ; Amarie, O.V. ; Wu, M. ; Amend, A.-L. ; Rubey, M. ; Gradinger, D. ; Irmler, M. ; Beckers, J. ; Rathkolb, B. ; Wolf, E. ; Feuchtinger, A. ; Huypens, P. ; Teperino, R. ; Rozman, J. ; Przemeck, G.K.H. ; Hrabě de Angelis, M.
PAX6 mutation alters circadian rhythm and beta cell function in mice without affecting glucose tolerance.Azimzadeh, O. ; Azizova, T. ; Merl-Pham, J. ; Blutke, A. ; Moseeva, M. ; Zubkova, O. ; Anastasov, N. ; Feuchtinger, A. ; Hauck, S.M. ; Atkinson, M.J. ; Tapio, S.
Chronic occupational exposure to ionizing radiation induces alterations in the structure and metabolism of the heart: A proteomic analysis of human formalin-fixed paraffin-embedded (FFPE) cardiac tissue.Neef, S.K. ; Winter, S. ; Hofmann, U. ; Mürdter, T.E. ; Schaeffeler, E. ; Horn, H. ; Buck, A. ; Walch, A.K. ; Hennenlotter, J. ; Ott, G. ; Fend, F. ; Bedke, J. ; Schwab, M. ; Haag, M.
Optimized protocol for metabolomic and lipidomic profiling in formalin-fixed paraffin-embedded kidney tissue by LC-MS.Slabik, C. ; Kalbarczyk, M. ; Danisch, S. ; Zeidler, R. ; Klawonn, F. ; Volk, V. ; Krönke, N. ; Feuerhake, F. ; Ferreira de Figueiredo, C. ; Blasczyk, R. ; Olbrich, H. ; Theobald, S.J. ; Schneider, A. ; Ganser, A. ; von Kaisenberg, C. ; Lienenklaus, S. ; Bleich, A. ; Hammerschmidt, W. ; Stripecke, R.
CAR-T cells targeting Epstein-Barr virus gp350 validated in a humanized mouse model of EBV infection and lymphoproliferative disease.Blutke, A. ; Sun, N. ; Xu, Z. ; Buck, A. ; Harrison, L. ; Schriever, S.C. ; Pfluger, P.T. ; Wiles, D. ; Kunzke, T. ; Huber, K. ; Schlegel, J. ; Aichler, M. ; Feuchtinger, A. ; Matiasek, K. ; Hauck, S.M. ; Walch, A.K.
Light sheet fluorescence microscopy guided MALDI-imaging mass spectrometry of cleared tissue samples.Geng, X. ; Babayeva, L. ; Walch, A.K. ; Aubele, M. ; Gross, E. ; Kiechle, M. ; Bronger, H. ; Dreyer, T. ; Magdolen, V. ; Dorn, J.
High levels of KLK7 protein expression are related to a favorable prognosis in triple-negative breast cancer patients.Turcu, A.F. ; Walch, A.K.
A multi-test strategy for adrenal tumours.Ščupáková, K. ; Dewez, F. ; Walch, A.K. ; Heeren, R.M.A. ; Balluff, B.
Morphometric cell classification for single-Cell MALDI-mass spectrometry imaging.Körber, N. ; Behrends, U. ; Protzer, U. ; Bauer, T.
Evaluation of T-activated proteins as recall antigens to monitor Epstein-Barr virus and human cytomegalovirus-specific T cells in a clinical trial setting.Fischer, A. ; Koopmans, T. ; Ramesh, P. ; Christ, S. ; Strunz, M. ; Wannemacher, J. ; Aichler, M. ; Feuchtinger, A. ; Walch, A.K. ; Ansari, M. ; Theis, F.J. ; Schorpp, K.K. ; Hadian, K. ; Neumann, P.A. ; Schiller, H. B. ; Rinkevich, Y.
Post-surgical adhesions are triggered by calcium-dependent membrane bridges between mesothelial surfaces.Zeeshan Chaudhry, M. ; Casalegno-Garduno, R. ; Sitnik, K.M. ; Kasmapour, B. ; Pulm, A.K. ; Brizic, I. ; Eiz-Vesper, B. ; Moosmann, A. ; Jonjic, S. ; Mocarski, E.S. ; Cicin-Sain, L.
Cytomegalovirus inhibition of extrinsic apoptosis determines fitness and resistance to cytotoxic CD8 T cells.Prorok, P. ; Artufel, M. ; Aze, A. ; Coulombe, P. ; Peiffer, I. ; Lacroix, L. ; Guédin, A. ; Mergny, J.L. ; Damaschke, J. ; Schepers, A. ; Cayrou, C. ; Teulade-Fichou, M.P. ; Ballester, B. ; Méchali, M.
Author Correction: Involvement of G-quadruplex regions in mammalian replication origin activity (Nature Communications, (2019), 10, 1, (3274), 10.1038/s41467-019-11104-0).Niu, Z. ; Sarkar, R. ; Aichler, M. ; Wester, H. ; Yousefi, B.H. ; Reif, B.
Mapping of the binding interface of PET tracer molecules and Alzheimer Disease Aβ fibrils using MAS solid-state NMR spectroscopy.Kühne, J.F. ; Neudörfl, C. ; Beushausen, K. ; Keil, J. ; Malysheva, S. ; Wandrer, F. ; Haller, H. ; Messerle, M. ; Blume, C. ; Neuenhahn, M. ; Schlott, F. ; Hammerschmidt, W. ; Zeidler, R. ; Falk, C.S.
Differential effects of Belatacept on virus-specific memory versus de novo allo-specific T cell responses of kidney transplant recipients and healthy donors.Li, F. ; Feuchtinger, A. ; Walch, A.K. ; Sun, N.
In situ metabolite mass spectrometry imaging: New insights into the adrenal gland.Adhikary, D. ; Damaschke, J. ; Mautner, J. ; Behrends, U.
The Epstein-Barr virus major tegument protein BNRF1 is a common target of cytotoxic CD4+ T cells.Bergmann, N. ; Delbridge, C. ; Gempt, J. ; Feuchtinger, A. ; Walch, A.K. ; Schirmer, L. ; Bunk, W. ; Aschenbrenner, T. ; Liesche-Starnecker, F. ; Schlegel, J.
The intratumoral heterogeneity reflects the intertumoral subtypes of glioblastoma multiforme: A regional immunohistochemistry analysis.Hedegger, K. ; Algül, H. ; Lesina, M. ; Blutke, A. ; Schmid, R.M. ; Schneider, M.R. ; Dahlhoff, M.
Unraveling ERBB network dynamics upon betacellulin signaling in pancreatic ductal adenocarcinoma in mice.Prade, V.M. ; Kunzke, T. ; Feuchtinger, A. ; Rohm, M. ; Luber, B. ; Lordick, F. ; Buck, A. ; Walch, A.K.
De novo discovery of metabolic heterogeneity with immunophenotype-guided imaging mass spectrometry.Bararia, D. ; Hildebrand, J.A. ; Stolz, S. ; Haebe, S. ; Alig, S. ; Trevisani, C.P. ; Osorio-Barrios, F. ; Bartoschek, M.D. ; Mentz, M. ; Pastore, A. ; Gaitzsch, E. ; Heide, M. ; Jurinovic, V. ; Rautter, K. ; Gunawardana, J. ; Sabdia, M.B. ; Szczepanowski, M. ; Richter, J. ; Klapper, W. ; Louissaint, A. ; Ludwig, C. ; Bultmann, S. ; Leonhardt, H. ; Eustermann, S. ; Hopfner, K.P. ; Hiddemann, W. ; von Bergwelt-Baildon, M. ; Steidl, C. ; Kridel, R. ; Tobin, J.W.D. ; Gandhi, M.K. ; Weinstock, D.M. ; Schmidt-Supprian, M. ; Sárosi, M.B. ; Rudelius, M. ; Passerini, V. ; Mautner, J. ; Weigert, O.
Cathepsin S alterations induce a tumor-promoting immune microenvironment in follicular lymphoma.Khaloian, S. ; Rath, E. ; Hammoudi, N. ; Gleisinger, E. ; Blutke, A. ; Giesbertz, P. ; Berger, E. ; Metwaly, A. ; Waldschmitt, N. ; Allez, M. ; Haller, D.
Mitochondrial impairment drives intestinal stem cell transition into dysfunctional Paneth cells predicting Crohn's disease recurrence.Lichtenegger, F.S. ; Schnorfeil, F.M. ; Rothe, M. ; Deiser, K. ; Altmann, T. ; Bücklein, V.L. ; Köhnke, T. ; Augsberger, C. ; Konstandin, N.P. ; Spiekermann, K. ; Moosmann, A. ; Boehm, S. ; Boxberg, M. ; Heemskerk, M.H.M. ; Goerlich, D. ; Wittmann, G. ; Wagner, B. ; Hiddemann, W. ; Schendel, D.J. ; Kvalheim, G. ; Bigalke, I. ; Subklewe, M.
Toll-like receptor 7/8-matured RNA-transduced dendritic cells as post-remission therapy in acute myeloid leukaemia: Results of a phase I trial.Buschle, A. ; Hammerschmidt, W.
Epigenetic lifestyle of Epstein-Barr virus.Huang, Y.M. ; Hong, X.Z. ; Shen, J. ; Huang, Y. ; Zhao, H.L.
China's oldest coronavirus survivors.Weigand, I. ; Schreiner, J. ; Röhrig, F. ; Sun, N. ; Landwehr, L.S. ; Urlaub, H. ; Kendl, S. ; Kiseljak-Vassiliades, K. ; Wierman, M.E. ; Angeli, J.P.F. ; Walch, A.K. ; Sbiera, S. ; Fassnacht, M. ; Kroiss, M.
Active steroid hormone synthesis renders adrenocortical cells highly susceptible to type II ferroptosis induction.Sun, N. ; Meyer, L.S. ; Feuchtinger, A. ; Kunzke, T. ; Knösel, T. ; Reincke, M. ; Walch, A.K. ; Williams, T.A.
Mass spectrometry imaging establishes 2 distinct metabolic phenotypes of aldosterone-producing cell clusters in primary aldosteronism.Voigt, S. ; Sterz, K. ; Giehler, F. ; Mohr, A.-W. ; Wilson, J.B. ; Moosmann, A. ; Kieser, A.
A central role of IKK2 and TPL2 in JNK activation and viral B-cell transformation.Delecluse, S. ; Poirey, R. ; Zeier, M. ; Schnitzler, P. ; Behrends, U. ; Tsai, M.H. ; Delecluse, H.J.
Identification and cloning of a new western Epstein-Barr virus strain that replicates efficiently in primary B cells.Riedel, E.O. ; Hinrichs, A. ; Kemter, E. ; Dahlhoff, M. ; Backman, M. ; Rathkolb, B. ; Prehn, C. ; Adamski, J. ; Renner, S. ; Blutke, A. ; Hrabě de Angelis, M. ; Bidlingmaier, M. ; Schopohl, J. ; Arnold, G.J. ; Fröhlich, T. ; Wolf, E.
Functional changes of the liver in the absence of growth hormone (GH) action - Proteomic and metabolomic insights from a GH receptor deficient pig model.Lohöfer, F. ; Buchholz, R. ; Glinzer, A. ; Huber, K. ; Haas, H. ; Kaissis, G. ; Feuchtinger, A. ; Aichler, M. ; Sporns, P.B. ; Höltke, C. ; Stölting, M. ; Schilling, F. ; Botnar, R.M. ; Kimm, M.A. ; Faber, C. ; Walch, A.K. ; Zernecke, A. ; Karst, U. ; Wildgruber, M.
Mass Spectrometry imaging of atherosclerosis-affine Gadofluorine following Magnetic Resonance imaging.Marschall, M. ; Strojan, H. ; Kiener, R. ; Wangen, C. ; Sonntag, E. ; Müller, R. ; Zeitträger, I. ; Wagner, S. ; Stamminger, T. ; Milbradt, J. ; Behrends, U. ; Körber, N. ; Bauer, T. ; Schrödel, S. ; Thirion, C. ; Wagner, R. ; Hutterer, C.
Differential upregulation of host cell protein kinases by the replication of α-, β- and γ-Herpesviruses provides a signature o virus-specific signalling.Schüttrumpf, L. ; Marschner, S. ; Scheu, K. ; Hess J. ; Rietzler, S. ; Walch, A.K. ; Baumeister, P. ; Kirchner, T. ; Ganswindt, U. ; Zitzelsberger, H. ; Belka, C. ; Maihoefer, C.
Definitive chemoradiotherapy in patients with squamous cell cancers of the head and neck-results from an unselected cohort of the clinical cooperation group "Personalized Radiotherapy in Head and Neck Cancer".Renner, S. ; Blutke, A. ; Clauss, S. ; Deeg, C.A. ; Kemter, E. ; Merkus, D. ; Wanke, R. ; Wolf, E.
Porcine models for studying complications and organ crosstalk in diabetes mellitus.Hofmann, I. ; Kemter, E. ; Theobalt, N. ; Fiedler, S. ; Bidlingmaier, M. ; Hinrichs, A. ; Aichler, M. ; Burkhardt, K. ; Klymiuk, N. ; Wolf, E. ; Wanke, R. ; Blutke, A.
Linkage between growth retardation and pituitary cell morphology in a dystrophin-deficient pig model of Duchenne muscular dystrophy.Kunzke, T. ; Buck, A. ; Prade, V.M. ; Feuchtinger, A. ; Prokopchuk, O. ; Martignoni, M.E. ; Heisz, S. ; Hauner, H. ; Janssen, K.P. ; Walch, A.K. ; Aichler, M.
Derangements of amino acids in cachectic skeletal muscle are caused by mitochondrial dysfunction.Altamura, S. ; Vegi, N.M. ; Hoppe, P.S. ; Schroeder, T. ; Aichler, M. ; Walch, A.K. ; Okreglicka, K. ; Hültner, L. ; Schneider, M. ; Ladinig, C. ; Kuklik-Roos, C. ; Mysliwietz, J. ; Janik, D. ; Neff, F. ; Rathkolb, B. ; Hrabě de Angelis, M. ; Buske, C. ; da Silva, A.R. ; Muedder, K. ; Conrad, M. ; Ganz, T. ; Kopf, M. ; Muckenthaler, M.U. ; Bornkamm, G.W.
Glutathione peroxidase 4 and vitamin E control reticulocyte maturation, stress erythropoiesis and iron homeostasis.Kreutzer, L. ; Aichler, M. ; Walch, A.K.
In situ metabolomics in cancer tissue by high-resolution mass spectrometry imaging.Baumann, P. ; Schriever, S.C. ; Kullmann, S. ; Zimprich, A. ; Feuchtinger, A. ; Amarie, O.V. ; Peter, A. ; Walch, A.K. ; Gailus-Durner, V. ; Fuchs, H. ; Hrabě de Angelis, M. ; Wurst, W. ; Tschöp, M.H. ; Heni, M. ; Hölter, S.M. ; Pfluger, P.T.
Dusp8 affects hippocampal size and behavior in mice and humans.Alterio, V. ; Kellner, M. ; Esposito, D. ; Liesche-Starnecker, F. ; Bua, S. ; Supuran, C.T. ; Monti, S.M. ; Zeidler, R. ; De Simone, G.
Biochemical and structural insights into Carbonic Anhydrase XII/Fab6A10 complex.Pan, C. ; Schoppe, O. ; Parra-Damas, A. ; Cai, R. ; Todorov, M.I. ; Gondi, G. ; von Neubeck, B. ; Böğürcü-Seidel, N. ; Seidel, S. ; Sleiman, K. ; Veltkamp, C. ; Förstera, B. ; Mai, H. ; Rong, Z. ; Trompak, O. ; Ghasemigharagoz, A. ; Reimer, M.A. ; Cuesta, A.M. ; Coronel, J. ; Jeremias, I. ; Saur, D. ; Acker-Palmer, A. ; Acker, T. ; Garvalov, B.K. ; Menze, B. ; Zeidler, R. ; Ertürk, A.
Deep learning reveals cancer metastasis and therapeutic antibody targeting in entire body.Correa-Gallegos, D. ; Jiang, D. ; Christ, S. ; Ramesh, P. ; Ye, H. ; Wannemacher, J. ; Kalgudde Gopal, S. ; Yu, Q. ; Aichler, M. ; Walch, A.K. ; Mirastschijski, U. ; Volz, T. ; Rinkevich, Y.
Patch repair of deep wounds by mobilized fascia.Yang, L. ; Gradl, R. ; Dierolf, M. ; Möller, W. ; Kutschke, D. ; Feuchtinger, A. ; Hehn, L. ; Donnelley, M. ; Günther, B. ; Achterhold, K. ; Walch, A.K. ; Stöger, T. ; Razansky, D. ; Pfeiffer, F. ; Morgan, K.S. ; Schmid, O.
Multimodal precision imaging of pulmonary nanoparticle delivery in mice: Dynamics of application, spatial distribution, and dosimetry.Seitz, S. ; Kwon, Y. ; Hartleben, G. ; Jülg, J. ; Sekar, R. ; Krahmer, N. ; Najafi, B. ; Loft, A. ; Gancheva, S. ; Stemmer, K. ; Feuchtinger, A. ; Hrabě de Angelis, M. ; Müller, T.D. ; Mann, M. ; Blüher, M. ; Roden, M. ; Berriel Diaz, M. ; Behrends, C. ; Gilleron, J. ; Herzig, S. ; Zeigerer, A.
Hepatic Rab24 controls blood glucose homeostasis via improving mitochondrial plasticity.Hollaus, A. ; Martin, L.K. ; Moosmann, A.
Targets of the T cell response to human herpesvirus 6B.Mohr, A.-W. ; Moosmann, A.
The T cell epitope repertoire of polyomavirus BK.Scheffler, L. ; Feicht, S. ; Strobl, L.J. ; Ehrenberg, S. ; Baccarini, M. ; Bornkamm, G.W. ; Zimber-Strobl, U.
B-Raf and Raf-1 are dispensable for activation of the MAPK/Erk signaling pathway in murine B cells but contribute to plasma cell differentiation.Huth, A. ; Liang, X. ; Krebs, S. ; Blum, H. ; Moosmann, A.
The antigen-specific T-cell receptor repertoire against human cytomegalovirus.Lechner, M. ; Engleitner, T. ; Oellinger, R. ; Rad, R. ; Schmidt-Supprian, M. ; Strobl, L.J. ; Zimber-Strobl, U.
"Two B or not two B?" The potency of Nntch2 in follicular vs marginal zone B cell identity.Stutte, S. ; Ruf, J. ; Kugler, I. ; Ishikawa-Ankerhold, H. ; Blutke, A. ; Marconi, P. ; Maeda, T. ; Kaisho, T. ; Krug, A. ; Lauterbach, H. ; Colonna, M. ; von Andrian, U. ; Brocker, T.
Type-I interferon regulates ghrelin-levels leading to anorexia and weight loss while promoting inflammatory immune responses.Cobo, M.F.L. ; Pircher, C. ; Dietze, K. ; Kammertöns, T. ; Gary, R. ; Moosmann, A. ; Mautner, J. ; Dornmair, K. ; Takvorian, A. ; Bullinger, L. ; Blankenstein, T. ; Gerbitz, A. ; Hansmann, L.
Single cell identification of defined ebv epitope-specific TCR alpha beta pairs for adoptive T cell transfer against EBV infection and EBV-associated malignancies.Arndt, D. ; Fux, R. ; Blutke, A. ; Schwaiger, J. ; El-Matbouli, M. ; Sutter, G. ; Langenmayer, M.C.
Proliferative kidney disease and proliferative darkening syndrome are linked with brown trout (Salmo trutta fario) mortalities in the pre-alpine Isar River.Pich, D. ; Mrozek-Gorska, P. ; Bouvet, M. ; Sugimoto, A. ; Akidil, E. ; Grundhoff, A. ; Hamperl, S. ; Ling, P.D. ; Hammerschmidt, W.
First days in the life of naïve human B-lymphocytes infected with Epstein-Barr Virus.Sammer, M. ; Teiluf, K. ; Girst, S. ; Greubel, C. ; Reindl, J. ; Ilicic, K. ; Walsh, D.W.M. ; Aichler, M. ; Walch, A.K. ; Combs, S.E. ; Wilkens, J.J. ; Dollinger, G. ; Schmid, T.E.
Beam size limit for pencil minibeam radiotherapy determined from side effects in an in-vivo mouse ear model.Wagner, A. ; Hofmeister, O. ; Rolland, S.G. ; Maiser, A. ; Aasumets, K. ; Schmitt, S. ; Schorpp, K.K. ; Feuchtinger, A. ; Hadian, K. ; Schneider, S. ; Zischka, H. ; Leonhardt, H. ; Conradt, B. ; Gerhold, J.M. ; Wolf, A.
Mitochondrial Alkbh1 localizes to mtRNA granules and its knockdown induces the mitochondrial UPR in humans and C. elegans.Murakami, M. ; Rhayem, Y. ; Kunzke, T. ; Sun, N. ; Feuchtinger, A. ; Ludwig, P. ; Strom, T.M. ; Gomez-Sanchez, C. ; Knösel, T. ; Kirchner, T. ; Williams, T.A. ; Reincke, M. ; Walch, A.K. ; Beuschlein, F.
In situ metabolomics of aldosterone-producing adenomas.Sun, N. ; Kunzke, T. ; Sbiera, S. ; Kircher, S. ; Feuchtinger, A. ; Aichler, M. ; Herterich, S. ; Ronchi, C.L. ; Weigand, I. ; Schlegel, N. ; Waldmann, J. ; Fragoso, M.C.V. ; Whitsett, T.G. ; Gill, A.J. ; Fassnacht, M. ; Walch, A.K. ; Kroiss, M.
Prognostic relevance of steroid sulfation in adrenocortical carcinoma revealed by molecular phenotyping using high resolution mass spectrometry imaging.Vincent-Fabert, C. ; Roland, L. ; Zimber-Strobl, U. ; Feuillard, J. ; Faumont, N.
Pre-clinical blocking of PD-L1 molecule, which expression is down regulated by NF-κB, JAK1/JAK2 and BTK inhibitors, induces regression of activated B-cell lymphoma.Siebert, C. ; Ciato, D. ; Murakami, M. ; Frei-Stuber, L. ; Perez-Rivas, L.G. ; Monteserin-Garcia, J.L. ; Noelting, S. ; Maurer, J. ; Feuchtinger, A. ; Walch, A.K. ; Haak, H.R. ; Bertherat, J. ; Mannelli, M. ; Fassnacht, M. ; Korpershoek, E. ; Reincke, M. ; Stalla, G.K. ; Hantel, C. ; Beuschlein, F.
Heat shock protein 90 as a prognostic marker and therapeutic target for adrenocortical carcinoma.Murer, A. ; Rühl, J. ; Zbinden, A. ; Capaul, R. ; Hammerschmidt, W. ; Chijioke, O. ; Münz, C.
MicroRNAs of Epstein-Barr Virus attenuate T-cell-mediated immune control in vivo (vol 10, e01941-18, 2019).Mrozek-Gorska, P. ; Buschle, A. ; Pich, D. ; Schwarzmayr, T. ; Fechtner, R. ; Scialdone, A. ; Hammerschmidt, W.
Epstein-Barr virus reprograms human B lymphocytes immediately in the prelatent phase of infection.Prorok, P. ; Artufel, M. ; Aze, A. ; Coulombe, P. ; Peiffer, I. ; Lacroix, L. ; Guédin, A. ; Mergny, J.L. ; Damaschke, J. ; Schepers, A. ; Ballester, B. ; Méchali, M.
Involvement of G-quadruplex regions in mammalian replication origin activity.Renner, S. ; Martins, A.S. ; Streckel, E. ; Braun-Reichhart, C. ; Backman, M. ; Prehn, C. ; Klymiuk, N. ; Bähr, A. ; Blutke, A. ; Landbrecht-Schessl, C. ; Wünsch, A. ; Kessler, B. ; Kurome, M. ; Hinrichs, A. ; Koopmans, S.J. ; Krebs, S. ; Kemter, E. ; Rathkolb, B. ; Nagashima, H. ; Blum, H. ; Ritzmann, M. ; Wanke, R. ; Aigner, B. ; Adamski, J. ; Hrabě de Angelis, M. ; Wolf, E.
Mild maternal hyperglycemia in INSC93S transgenic pigs causes impaired glucose tolerance and metabolic alterations in neonatal offspring.Rehm, S.R.T. ; Smirnova, N.F. ; Morrone, C. ; Götzfried, J. ; Feuchtinger, A. ; Pedersen, J. ; Korkmaz, B. ; Yildirim, A.Ö. ; Jenne, D.
Premedication with a cathepsin C inhibitor alleviates early primary graft dysfunction in mouse recipients after lung transplantation.Yang, L. ; Gradl, R. ; Feuchtinger, A. ; Morgan, K.S. ; Kutschke, D. ; Stöger, T. ; Razansky, D. ; Walch, A.K. ; Pfeiffer, F. ; Schmidt, O.
Novel imaging tolls for deciphering pulmonary aerosol deposition with single-cell resolution in non-dissected murine lungs.Sigmund, F. ; Pettinger, S. ; Kube, M. ; Schneider, F. ; Schifferer, M. ; Schneider, S. ; Efremova, M.V. ; Pujol-Martí, J. ; Aichler, M. ; Walch, A.K. ; Misgeld, T. ; Dietz, H. ; Westmeyer, G.G.
Iron-sequestering nanocompartments as multiplexed Electron Microscopy gene reporters.Schneider, A. ; Kurz, S. ; Manske, K. ; Janas, M.K. ; Heikenwälder, M. ; Misgeld, T. ; Aichler, M. ; Weissmann, S.F. ; Zischka, H. ; Knolle, P. ; Wohlleber, D.
Single organelle analysis to characterize mitochondrial function and crosstalk during viral infection.Wintergerst, L. ; Selmansberger, M. ; Maihoefer, C. ; Schuettrumpf, L. ; Walch, A.K. ; Wilke, C. ; Pitea, A. ; Woischke, C. ; Baumeister, P. ; Kirchner, T. ; Belka, C. ; Ganswindt, U. ; Zitzelsberger, H. ; Unger, K. ; Hess J.
A 16q24.3 4-gene mRNA signature predicts outcome in radio(chemo)therapy-treated head and neck squamous cell carcinoma.Hess J. ; Unger, K. ; Maihoefer, C. ; Schuettrumpf, L. ; Schneider, L. ; Heider, T. ; Weber, P. ; Marschner, S. ; Braselmann, H. ; Kuger, S. ; Pflugradt, U. ; Baumeister, P. ; Walch, A.K. ; Woischke, C. ; Kirchner, T. ; Werner, M. ; Werner, K. ; Baumann, M. ; Budach, V. ; Combs, S.E. ; Debus, J. ; Grosu, A.-L. ; Krause, M. ; Roedel, C. ; Stuschke, M. ; Zips, D. ; Zitzelsberger, H. ; Ganswindt, U. ; Henke, M. ; Belka, C.
A five-microRNA-signature predicts recurrence and survival in HPV-negative HNSCC.Wiesner, M. ; Glawischnig, W. ; Lutzmann, I. ; Grimm, F. ; Blutke, A.
Autochthonous Taenia crassiceps infection in a ring-tailed lemur (Lemur catta) in the Salzburg Zoo.Huber, K. ; Kunzke, T. ; Buck, A. ; Langer, R. ; Luber, B. ; Feuchtinger, A. ; Walch, A.K.
Multimodal analysis of formalin-fixed and paraffin-embedded tissue by MALDI imaging and fluorescence in situ hybridization for combined genetic and metabolic analysis.von Gamm, M. ; Schaub, A. ; Jones, A. ; Wolf, C. ; Behrens, G. ; Lichti, J. ; Essig, K. ; Macht, A. ; Pircher, J. ; Ehrlich, A. ; Davari, K. ; Chauhan, D. ; Busch, B. ; Wurst, W. ; Feederle, R. ; Feuchtinger, A. ; Tschöp, M.H. ; Friedel, C.C. ; Hauck, S.M. ; Sattler, M. ; Geerlof, A. ; Hornung, V. ; Heissmeyer, V. ; Schulz, C. ; Heikenwalder, M. ; Glasmacher, E.
Immune homeostasis and regulation of the interferon pathway require myeloid-derived Regnase-3.Backman, M. ; Flenkenthaler, F. ; Blutke, A. ; Dahlhoff, M. ; Ländström, E. ; Renner, S. ; Philippou-Massier, J. ; Krebs, S. ; Rathkolb, B. ; Prehn, C. ; Grzybek, M. ; Coskun, Ü. ; Rothe, M. ; Adamski, J. ; Hrabě de Angelis, M. ; Wanke, R. ; Fröhlich, T. ; Arnold, G.J. ; Blum, H. ; Wolf, E.
Multi-omics insights into functional alterations of the liver in insulin-deficient diabetes mellitus.Dombrowsky, A. ; Schauer, J. ; Sammer, M. ; Blutke, A. ; Walsh, D.W.M. ; Schwarz, B. ; Bartzsch, S. ; Feuchtinger, A. ; Reindl, J. ; Combs, S.E. ; Dollinger, G. ; Schmid, T.E.
Acute skin damage and late radiation-induced fibrosis and inflammation in murine ears after high-dose irradiation.Bechmann, N. ; Poser, I. ; Seifert, V. ; Greunke, C. ; Ullrich, M. ; Qin, N. ; Walch, A.K. ; Peitzsch, M. ; Robledo, M. ; Pacak, K. ; Pietzsch, J. ; Richter, S. ; Eisenhofer, G.
Impact of extrinsic and intrinsic hypoxia on catecholamine biosynthesis in absence or presence of Hif2 alpha in pheochromocytoma cells.Schaeffner, M. ; Mrozek-Gorska, P. ; Buschle, A. ; Woellmer, A. ; Tagawa, T. ; Cernilogar, F.M. ; Schotta, G. ; Krietenstein, N. ; Lieleg, C. ; Korber, P. ; Hammerschmidt, W.
BZLF1 interacts with chromatin remodelers promoting escape from latent infections with EBV.Kalbarczyk, M. ; Slabik, C. ; Danisch, S. ; Cornelius, A. ; Zeidler, R. ; Kroenke, N. ; Feuerhake, F. ; Stripecke, R.
Cord blood derived CAR-T cells targeting gp350 containing CD28/CD3 zeta or 4-1BB/CD3 zeta signaling domains directly react against cells infected with EBV bypassing the need of HLA-matched memory T cells.Reulen, H.J. ; Suero Molina, E. ; Zeidler, R. ; Gildehaus, F.J. ; Böning, G. ; Gosewisch, A. ; Stummer, W.
Intracavitary radioimmunotherapy of high-grade gliomas: Present status and future developments.Sperling, S. ; Fiedler, P. ; Lechner, M. ; Pollithy, A. ; Ehrenberg, S. ; Schiefer, A.I. ; Kenner, L. ; Feuchtinger, A. ; Kühn, R. ; Swinerd, G. ; Schmidt-Supprian, M. ; Strobl, L.J. ; Zimber-Strobl, U.
Chronic CD30 signaling in B cells results in lymphomagenesis by driving the expansion of plasmablasts and B1 cells.Weber, J. ; de la Rosa, J. ; Grove, C.S. ; Schick, M. ; Rad, L. ; Baranov, O. ; Strong, A. ; Pfaus, A. ; Friedrich, M.J. ; Engleitner, T. ; Lersch, R. ; Öllinger, R. ; Grau, M. ; Menendez, I.G. ; Martella, M. ; Kohlhofer, U. ; Banerjee, R. ; Turchaninova, M.A. ; Scherger, A. ; Hoffman, G.J. ; Hess J. ; Kuhn, L. ; Ammon, T. ; Kim, J. ; Schneider, G. ; Unger, K. ; Zimber-Strobl, U. ; Heikenwälder, M. ; Schmidt-Supprian, M. ; Yang, F. ; Saur, D. ; Liu, P. ; Steiger, K. ; Chudakov, D.M. ; Lenz, G. ; Quintanilla-Martinez, L. ; Keller, U. ; Vassiliou, G.S. ; Cadiñanos, J. ; Bradley, A. ; Rad, R.
PiggyBac transposon tools for recessive screening identify B-cell lymphoma drivers in mice.Ratner, C. ; He, Z. ; Grunddal, K.V. ; Skov, L.J. ; Hartmann, B. ; Zhang, F. ; Feuchtinger, A. ; Bjerregaard, A. ; Christoffersen, C. ; Tschöp, M.H. ; Finan, B. ; DiMarchi, R.D. ; Leinninger, G.M. ; Williams, K.W. ; Clemmensen, C. ; Holst, B.
Long-acting neurotensin synergizes with liraglutide to reverse obesity through a melanocortin-dependent pathway.Gujrati, V. ; Prakash, J. ; Malekzadeh Najafabadi, J. ; Stiel, A.-C. ; Klemm, U. ; Mettenleiter, G. ; Aichler, M. ; Walch, A.K. ; Ntziachristos, V.
Bioengineered bacterial vesicles as biological nano-heaters for optoacoustic imaging.Papathomas, T.G. ; Sun, N. ; Chortis, V. ; Taylor, A.E. ; Arlt, W. ; Richter, S. ; Eisenhofer, G. ; Ruiz-Babot, G. ; Guasti, L. ; Walch, A.K.
Novel methods in adrenal research: A metabolomics approach.Gärtner, K. ; Luckner, M. ; Wanner, G. ; Zeidler, R.
Engineering extracellular vesicles as novel treatment options: exploiting herpesviral immunity in CLL.Köhler, K. ; Sanchez-Pulido, L. ; Höfer, V. ; Marko, A. ; Ponting, C.P. ; Snijders, A.P. ; Feederle, R. ; Schepers, A. ; Boos, D.
The Cdk8/19-cyclin C transcription regulator functions in genome replication through metazoan Sld7.Ogrinc Wagner, A. ; Friedrich, V. ; Barthels, C. ; Marconi, P. ; Blutke, A. ; Brombacher, F. ; Brocker, T.
Strain specific maturation of Dendritic cells and production of IL-1β controls CD40-driven colitis.Norheim, F. ; Hasin-Brumshtein, Y. ; Vergnes, L. ; Chella Krishnan, K. ; Pan, C. ; Seldin, M.M. ; Hui, S.T. ; Mehrabian, M. ; Zhou, Z. ; Gupta, S. ; Parks, B.W. ; Walch, A.K. ; Reue, K. ; Hofmann, S.M. ; Arnold, A.P. ; Lusis, A.J.
Gene-by-sex interactions in mitochondrial functions and cardio-metabolic traits.Vincent-Fabert, C. ; Saintamand, A. ; David, A. ; Alizadeh, M. ; Boyer, F. ; Arnaud, N. ; Zimber-Strobl, U. ; Feuillard, J. ; Faumont, N.
Reproducing indolent B-cell lymphoma transformation with T-cell immunosuppression in LMP1/CD40-expressing mice.Murer, A. ; Rühl, J. ; Zbinden, A. ; Capaul, R. ; Hammerschmidt, W. ; Chijioke, O. ; Münz, C.
MicroRNAs of Epstein-Barr Virus attenuate T-cell-mediated immune control in vivo.Danisch, S. ; Slabik, C. ; Cornelius, A. ; Albanese, M. ; Tagawa, T. ; Chen, Y.-F. A. ; Krönke, N. ; Eiz-Vesper, B. ; Lienenklaus, S. ; Bleich, A. ; Theobald, S.J. ; Schneider, A. ; Ganser, A. ; von Kaisenberg, C. ; Zeidler, R. ; Hammerschmidt, W. ; Feuerhake, F. ; Stripecke, R.
Spatiotemporally skewed activation of PD-1 T cells after epstein barr virus infection and tumor development in long-term fully humanized mice.Balluff, B. ; Buck, A. ; Martin-Lorenzo, M. ; Dewez, F. ; Langer, R. ; McDonnell, L.A. ; Walch, A.K. ; Heeren, R.M.A.
Integrative clustering in mass spectrometry imaging for enhanced patient stratification.Yang, L. ; Feuchtinger, A. ; Möller, W. ; Ding, Y. ; Kutschke, D. ; Möller, G. ; Schittny, J.C. ; Burgstaller, G. ; Hofmann, W. ; Stöger, T. ; Razansky, D. ; Walch, A.K. ; Schmid, O.
Three-dimensional quantitative co-mapping of pulmonary morphology and nanoparticle distribution with cellular resolution in non-dissected murine lungs.Yamano, T. ; Steinert, M. ; Steer, B. ; Klein, L. ; Hammerschmidt, W. ; Adler, H.
B cells latently infected with murine gammaherpesvirus 68 (MHV-68) are present in the mouse thymus-A step toward immune evasion?Görgülü, K. ; Diakopoulos, K.N. ; Ai, J. ; Schoeps, B. ; Kabacaoglu, D. ; Karpathaki, A.F. ; Ciecielski, K.J. ; Kaya-Aksoy, E. ; Ruess, D.A. ; Berninger, A. ; Kowalski, M. ; Stevanovic, M. ; Wörmann, S.M. ; Wartmann, T. ; Zhao, Y. ; Halangk, W. ; Voronina, S. ; Tepikin, A. ; Schlitter, A.M. ; Steiger, K. ; Artati, A. ; Adamski, J. ; Aichler, M. ; Walch, A.K. ; Jastroch, M. ; Hartleben, G. ; Mantzoros, C.S. ; Weichert, W. ; Schmid, R.M. ; Herzig, S. ; Krüger, A. ; Sainz, B. ; Lesina, M. ; Algül, H.
Levels of the autophagy-related 5 protein affect progression and metastasis of pancreatic tumors in mice.Harrison, L. ; Schriever, S.C. ; Feuchtinger, A. ; Kyriakou, E. ; Baumann, P. ; Pfuhlmann, K. ; Messias, A.C. ; Walch, A.K. ; Tschöp, M.H. ; Pfluger, P.T.
Fluorescent blood-brain barrier tracing shows intact leptin transport in obese mice.Hess J. ; Unger, K. ; Maihoefer, C. ; Schüttrumpf, L. ; Wintergerst, L. ; Heider, T. ; Weber, P. ; Marschner, S. ; Braselmann, H. ; Samaga, D. ; Kuger, S. ; Pflugradt, U. ; Baumeister, P. ; Walch, A.K. ; Woischke, C. ; Kirchner, T. ; Werner, M. ; Werner, K. ; Baumann, M. ; Budach, V. ; Combs, S.E. ; Debus, J. ; Grosu, A.-L. ; Krause, M. ; Linge, A. ; Rödel, C. ; Stuschke, M. ; Zips, D. ; Zitzelsberger, H. ; Ganswindt, U. ; Henke, M. ; Belka, C.
A five-microRNA signature predicts survival and disease control of patients with head and neck cancer negative for HPV-infection.Stripecke, R. ; Danisch, S. ; Slabik, C. ; Zeidler, R. ; Hammerschmidt, W. ; Feuerhake, F. ; Ganser, A.
Pembrolizumab therapy exacerbates EBV-induced infections and tumors in a long-term fully humanized mouse model.Kuhn, L. ; Zapf, S.S. ; Djermanovic, K. ; Strobl, D.C. ; Weih, F. ; Blum, H. ; Weigert, O. ; Strobl, L.J. ; Zimber-Strobl, U.
The non-canonical NF-kappaB Signaling Pathway Contributes to the Expansion and Lymphomagenesis of CD40-activated B Cells.Passerini, V. ; Bösl, M.R. ; Silkenstedt, E. ; Osterode, E. ; Heide, M. ; Kridel, R. ; Ziegenhain, C. ; Staiger, A.M. ; Ott, G. ; Szczepanowski, M. ; Richter, J. ; Klapper, W. ; Rosenwald, A. ; Enard, W. ; Hiddemann, W. ; Bararia, D. ; Zimber-Strobl, U. ; Weigert, O.
PARP14 is a novel therapeutic target in STAT6 mutant follicular lymphoma.Danisch, S. ; Slabik, C. ; Zeidler, R. ; Ganser, A. ; Stripecke, R.
CAR-T cells targeting gp350 recognize immortalized cells latently infected with EBV.Delecluse, S. ; Tsai, M.H. ; Shumilov, A. ; Bencun, M. ; Arrow, S. ; Beshirova, A. ; Cottignies-Calamarte, A. ; Lasitschka, F. ; Bulut, O.C. ; Münz, C. ; Zeier, M. ; Behrends, U. ; Delecluse, H.J.
Epstein-Barr virus induces expression of the LPAM-1 integrin in B cells in vitro and in vivo.Fernandez, I.E. ; Sun, N. ; Wei, M. ; Witting, M. ; Aichler, M. ; Verleden, S. ; Schmitt-Kopplin, P. ; Walch, A.K. ; Eickelberg, O.
Pharmacometabolic effect of pirfenidone treatment in IPF detected by high resolution MALDI-FTICR imaging.Kempkes, B.
Structure and function of the EBNA2/PLK1 protein complex.van Zyl, D.G. ; Tsai, M. ; Shumilov, A. ; Schneidt, V. ; Poirey, R. ; Schlehe, B. ; Fluhr, H. ; Mautner, J. ; Delecluse, H.-J.
Immunogenic particles with a broad antigenic spectrum stimulate cytolytic T cells and offer increased protection against EBV infection ex vivo and in mice.Huth, A. ; Liang, X. ; Krebs, S. ; Blum, H. ; Moosmann, A.
Antigen-specific TCR signatures of cytomegalovirus infection.Théry, C. ; Witwer, K.W. ; Aikawa, E. ; Alcaraz, M.J. ; Anderson, J.D. ; Andriantsitohaina, R. ; Antoniou, A.C. ; Arab, T. ; Archer, F. ; Atkin-Smith, G.K. ; Ayre, D.C. ; Bach, J.M. ; Bachurski, D. ; Baharvand, H. ; Balaj, L. ; Baldacchino, S. ; Bauer, N.N. ; Baxter, A.A. ; Bebawy, M. ; Beckham, C. ; Bedina Zavec, A. ; Benmoussa, A. ; Berardi, A.C. ; Bergese, P. ; Bielska, E. ; Blenkiron, C. ; Bobis-Wozowicz, S. ; Boilard, E. ; Boireau, W. ; Bongiovanni, A. ; Borràs, F.E. ; Bosch, S. ; Boulanger, C.M. ; Breakefield, X. ; Breglio, A.M. ; Brennan, M. ; Brigstock, D.R. ; Brisson, A. ; Broekman, M.L.D. ; Bromberg, J.F. ; Bryl-Górecka, P. ; Buch, S. ; Buck, A.H. ; Burger, D. ; Busatto, S. ; Buschmann, D. ; Bussolati, B. ; Buzás, E.I. ; Byrd, J.B. ; Camussi, G. ; Carter, D.R.F. ; Gärtner, K. ; Kawamura, Y. ; Keller, E.T. ; Khamari, D. ; Chen, C. ; Chen, S. ; Cheng, L. ; Chin, A.R. ; Clayton, A. ; Clerici, S.P. ; Cocks, A. ; Cocucci, E. ; Coffey, R.J. ; Cordeiro-da-Silva, A. ; Couch, Y. ; Coumans, F.A.W. ; Coyle, B. ; Crescitelli, R. ; Criado, M.F. ; D’Souza-Schorey, C. ; Das, S. ; de Candia, P. ; De Santana, E.F.
Minimal information for studies of extracellular vesicles 2018 (MISEV2018): A position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines.Clemmensen, C. ; Jall, S. ; Kleinert, M. ; Quarta, C. ; Gruber, T. ; Reber, J. ; Sachs, S. ; Fischer, K. ; Feuchtinger, A. ; Karlas, A. ; Simonds, S.E. ; Grandl, G. ; Loher, D. ; Sanchez-Quant, E. ; Keipert, S. ; Jastroch, M. ; Hofmann, S.M. ; Nascimento, E.B.M. ; Schrauwen, P. ; Ntziachristos, V. ; Cowley, M.A. ; Finan, B. ; Müller, T.D. ; Tschöp, M.H.
Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes (vol 9, 4304, 2018).Fernandez, I.E. ; Sun, N. ; Wei, M. ; Witting, M. ; Aichler, M. ; Verleden, S. ; Schmitt-Kopplin, P. ; Eickelberg, O. ; Walch, A.K.
Pharmacometabolic response to pirfenidone treatment in pulmonary fibrosis detected by high resolution MALDI FTICR-mass spectrometry imaging.Clemmensen, C. ; Jall, S. ; Kleinert, M. ; Quarta, C. ; Gruber, T. ; Reber, J. ; Sachs, S. ; Fischer, K. ; Feuchtinger, A. ; Karlas, A. ; Simonds, S.E. ; Grandl, G. ; Loher, D. ; Sanchez-Quant, E. ; Keipert, S. ; Jastroch, M. ; Hofmann, S.M. ; Nascimento, E.B.M. ; Schrauwen, P. ; Ntziachristos, V. ; Cowley, M.A. ; Finan, B. ; Müller, T.D. ; Tschöp, M.H.
Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes.Mangolini, M. ; Götte, F. ; Moore, A. ; Ammon, T. ; Oelsner, M. ; Lutzny-Geier, G. ; Klein-Hitpass, L. ; Williamson, J.C. ; Lehner, P.J. ; Dürig, J. ; Möllmann, M. ; Rásó-Barnett, L. ; Hughes, K. ; Santoro, A. ; Méndez-Ferrer, S. ; Oostendorp, R.A.J. ; Zimber-Strobl, U. ; Peschel, C. ; Hodson, D.J. ; Schmidt-Supprian, M. ; Ringshausen, I.
Notch2 controls non-autonomous Wnt-signalling in chronic lymphocytic leukaemia.Wintergerst, L. ; Selmansberger, M. ; Maihoefer, C. ; Schüttrumpf, L. ; Walch, A.K. ; Wilke, C. ; Pitea, A. ; Woischke, C. ; Baumeister, P. ; Kirchner, T. ; Belka, C. ; Ganswindt, U. ; Zitzelsberger, H. ; Unger, K. ; Hess J.
A prognostic mRNA expression signature of four 16q24.3 genes in radio(chemo)therapy-treated head and neck squamous cell carcinoma (HNSCC).Huang, S. ; Park, J. ; Qiu, C. ; Chung, K.F. ; Li, S.Y. ; Sirin, Y. ; Han, S.H. ; Taylor, V. ; Zimber-Strobl, U. ; Susztak, K.
Jagged1/Notch2 controls kidney fibrosis via Tfam-mediated metabolic reprogramming.Suwandhi, L. ; Hausmann, S. ; Braun, A. ; Gruber, T. ; Heinzmann, S.S. ; Gálvez, E.J.C. ; Buck, A. ; Legutko, B. ; Israel, A. ; Feuchtinger, A. ; Haythorne, E. ; Staiger, H. ; Heni, M. ; Häring, H.-U. ; Schmitt-Kopplin, P. ; Walch, A.K. ; Cáceres, C.G. ; Tschöp, M.H. ; Rutter, G.A. ; Strowig, T. ; Elsner, M. ; Ussar, S.
Chronic d-serine supplementation impairs insulin secretion.Zoni, E. ; Buck, A. ; Feuchtinger, A. ; Spahn, M. ; Walch, A.K. ; Kruithof-de Julio, M.
Metabolic signature in lethal vs. nonlethal prostate cancer.Clemen, C.S. ; Winter, L. ; Strucksberg, K.H. ; Berwanger, C. ; Türk, M. ; Kornblum, C. ; Florin, A. ; Aguilar-Pimentel, J.A. ; Amarie, O.V. ; Becker, L. ; Garrett, L. ; Hans, W. ; Moreth, K. ; Neff, F. ; Pingen, L. ; Rathkolb, B. ; Rácz, I. ; Rozman, J. ; Treise, I. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Vorgerd, M. ; Eichinger, L. ; Schröder, R.
The heterozygous R155C VCP mutation: Toxic in humans! Harmless in mice?International Wheat Genome Sequencing Consortium (Eversole, K. ; Feuillet, C. ; Keller, B. ; Rogers, J. ; Stein, N. ; Appels, R.) ; Pozniak, C.J. ; Choulet, F. ; Distelfeld, A. ; Poland, J. ; Ronen, G ; Sharpe, A.G. ; Pozniak, C. ; Barad, O. ; Baruch, K. ; Choulet, F. ; Keeble-Gagnère, G. ; Mascher, M. ; Ben-Zvi, G. ; Josselin, A.A. ; Himmelbach, A. ; Balfourier, F. ; Gutierrez-Gonzalez, J. ; Hayden, M. ; Josselin, A.A. ; Koh, C. ; Muehlbauer, G. ; Pasam, R.K. ; Paux, E. ; Rigault, P. ; Tibbits, J. ; Tiwari, V. ; Choulet, F. ; Spannagl, M. ; Lang, D. ; Gundlach, H. ; Haberer, G. ; Mayer, K.F.X. ; Ormanbekova, D. ; Paux, E. ; Prade, V.M. ; Šimková, H. ; Wicker, T. ; Swarbreck, D. ; Rimbert, H. ; Guilhot, N. ; Kaithakottil, G. ; Keilwagen, J. ; Leroy, P. ; Lux, T. ; Twardziok, S.O. ; Venturini, L. ; Juhász, A ; Abrouk, M ; Fischer, I.P. ; Uauy, C. ; Borrill, P ; Ramirez-Gonzalez, R.H. ; Arnaud, D. ; Chalabi, S. ; Chalhoub, B. ; Cory, A. ; Datla, R. ; Davey, M.W. ; Hayden, M. ; Jacobs, J. ; Robinson, S.J. ; Steuernagel, B. ; Tibbits, J. ; Tiwari, V. ; van Ex, F. ; Wulff, B.B.H. ; Robinson, S.J. ; Cory, A. ; Benhamed, M. ; Paux, E. ; Bendahmane, A. ; Concia, L. ; Latrasse, D. ; Rogers, J. ; Alaux, M. ; Bartoš, J. ; Bellec, A. ; Berges, H. ; Doležel, J. ; Frenkel, Z ; Gill, B. ; Korol, A. ; Letellier, T. ; Olsen, O.A. ; Singh, K. ; Valárik, M. ; van der Vossen, E. ; Vautrin, S. ; Weining, S. ; Korol, A. ; Frenkel, Z. ; Fahima, T. ; Glikson, V. ; Raats, D. ; Tiwari, V. ; Gill, B. ; Paux, E. ; Číhalíková, J. ; Toegelová, H. ; Vrána, J. ; Sourdille, P. ; Darrier, B. ; Barabaschi, D. ; Cattivelli, L ; Hernandez, P. ; Galvez, S. ; Budak, H. ; Jones, J.D.G. ; Witek, K. ; Yu, G. ; Small, I. ; Melonek, J. ; Zhou, R. ; Juhász, A. ; Belova, T. ; Kanyuka, K. ; King, R. ; Nilsen, K. ; Walkowiak, S. ; Cuthbert, R. ; Datla, R. ; Knox, R. ; Wiebe, K. ; Xiang, D. ; Rohde, A. ; Golds, T. ; Čížková, J. ; Akpinar, B.A. ; Biyiklioglu, S. ; Muehlbauer, G. ; Gao, L. ; Gutierrez-Gonzalez, J. ; N'Daiye, A. ; Číhalíková, J. ; Kubaláková, M. ; Šafář, J. ; Berges, H. ; Bellec, A. ; Vautrin, S. ; Alaux, M. ; Alfama, F. ; Adam-Blondon, A.F. ; Flores, R. ; Guerche, C. ; Letellier, T. ; Loaec, M. ; Quesneville, H. ; Condie, J. ; Ens, J. ; Koh, C. ; Maclachlan, R. ; Tan, Y. ; Paux, E. ; Alberti, A. ; Aury, J.M. ; Barbe, V. ; Couloux, A. ; Cruaud, C. ; Labadie, K. ; Mangenot, S. ; Wincker, P. ; Gill, B. ; Kaur, G. ; Luo, M. ; Sehgal, S. ; Chhuneja, P. ; Gupta, O.P. ; Jindal, S. ; Kaur, P. ; Malik, P. ; Sharma, P. ; Yadav, B. ; Singh, N.K. ; Khurana, J. ; Chaudhary, C. ; Khurana, P. ; Kumar, V. ; Mahato, A. ; Mathur, S. ; Sevanthi, A. ; Sharma, N. ; Tomar, R.S. ; Jacobs, J. ; Alaux, M. ; Bellec, A. ; Berges, H. ; Frenkel, Z. ; Gill, B. ; Korol, A. ; van der Vossen, E. ; Vautrin, S. ; Kaur, G. ; Luo, M. ; Sehgal, S. ; Bartoš, J. ; Holušová, K. ; Plíhal, O. ; Clark, M.D. ; Heavens, D. ; Kettleborough, G. ; Wright, J. ; Valárik, M. ; Abrouk, M. ; Balcárková, B. ; Holušová, K. ; Hu, Y. ; Luo, M. ; Salina, E. ; Ravin, N. ; Skryabin, K. ; Beletsky, A. ; Kadnikov, V. ; Mardanov, A. ; Nesterov, M. ; Rakitin, A. ; Sergeeva, E. ; Handa, H. ; Kanamori, H. ; Katagiri, S. ; Kobayashi, F. ; Nasuda, S. ; Tanaka, T. ; Wu, J. ; Hayden, M. ; Rigault, P. ; Cattonaro, F. ; Jiumeng, M. ; Kugler, K.G. ; Pfeifer, M. ; Sandve, S. ; Xun, X. ; Zhan, B. ; Abrouk, M. ; Batley, J. ; Bayer, P.E. ; Edwards, D. ; Hayashi, S. ; Tulpová, Z. ; Visendi, P. ; Weining, S. ; Cui, L. ; Du, X. ; Feng, K. ; Nie, X. ; Tong, W.G. ; Wang, L. ; Galvez, S. ; Lux, T. ; Ramirez-Gonzalez, R.H. ; Venturini, L. ; Hernandez, P ; Kanyuka, K ; Paux, E.
Shifting the limits in wheat research and breeding using a fully annotated reference genome.Sun, N. ; Fernandez, I.E. ; Wei, M. ; Witting, M. ; Aichler, M. ; Feuchtinger, A. ; Burgstaller, G. ; Verleden, S.E. ; Schmitt-Kopplin, P. ; Eickelberg, O. ; Walch, A.K.
Pharmacometabolic response to pirfenidone in pulmonary fibrosis detected by MALDI-FTICR-MSI.Gora, T. ; Burkhardt, R. ; Umkehrer, S. ; Herzen, J. ; Schilling, D. ; Feuchtinger, A. ; Walch, A.K. ; Schmid, T.E. ; Multhoff, G. ; Noel, P.B. ; Rummeny, E.J. ; Pfeiffer, F. ; Combs, S.E. ; Wilkens, J.J.
Detection of radiation induced lung fibrosis using x-ray dark-field imaging in a murine model.Ghasemi, A. ; Mohammad, N. ; Mautner, J. ; Taghipour Karsabet, M. ; Amani, J. ; Ardjmand, A. ; Vakili, Z.
Immunization with a recombinant fusion protein protects mice against Helicobacter pylori infection.Martin-Medina, A. ; Lehmann, M. ; Burgy, O. ; Hermann, S. ; Baarsma, H.A. ; Wagner, D.E. ; De Santis, M. ; Ciolek, F. ; Hofer, T.P. ; Frankenberger, M. ; Aichler, M. ; Lindner, M. ; Gesierich, W. ; Guenther, A. ; Walch, A.K. ; Coughlan, C. ; Wolters, P. ; Lee, J.S. ; Behr, J. ; Königshoff, M.
Increased extracellular vesicles mediate WNT5A signaling in idiopathic pulmonary fibrosis.Lino, A.C. ; Dang, V.D. ; Lampropoulou, V. ; Welle, A. ; Joedicke, J. ; Pohar, J. ; Simon, Q. ; Thalmensi, J. ; Baures, A. ; Flühler, V. ; Sakwa, I. ; Stervbo, U. ; Ries, S. ; Jouneau, L. ; Boudinot, P. ; Tsubata, T. ; Adachi, T. ; Hutloff, A. ; Dörner, T. ; Zimber-Strobl, U. ; de Vos, A.F. ; Dahlke, K. ; Loh, G. ; Korniotis, S. ; Goosmann, C. ; Weill, J.C. ; Reynaud, C.A. ; Kaufmann, S.H.E. ; Walter, J. ; Fillatreau, S.
LAG-3 inhibitory receptor expression identifies immunosuppressive natural regulatory plasma cells.Kazokaite, J. ; Niemans, R. ; Dudutiene, V. ; Becker, H.M. ; Leitans, J. ; Zubriene, A. ; Baranauskiene, L. ; Gondi, G. ; Zeidler, R. ; Matuliene, J. ; Tars, K. ; Yaromina, A. ; Lambin, P. ; Dubois, L.J. ; Matulis, D.
Novel fluorinated carbonic anhydrase IX inhibitors reduce hypoxia-induced acidification and clonogenic survival of cancer cells.Buck, A. ; Heijs, B. ; Beine, B. ; Schepers, J. ; Cassese, A. ; Heeren, R.M.A. ; McDonnell, L.A. ; Henkel, C. ; Walch, A.K. ; Balluff, B.
Round robin study of formalin-fixed paraffin-embedded tissues in mass spectrometry imaging.Maihoefer, C. ; Schüttrumpf, L. ; Macht, C. ; Pflugradt, U. ; Hess J. ; Schneider, L. ; Woischke, C. ; Walch, A.K. ; Baumeister, P. ; Kirchner, T. ; Zitzelsberger, H. ; Belka, C. ; Ganswindt, U.
Postoperative (chemo) radiation in patients with squamous cell cancers of the head and neck - clinical results from the cohort of the clinical cooperation group "Personalized Radiotherapy in Head and Neck Cancer".Schneidt, V. ; Ilecka, M. ; Dreger, P. ; van Zyl, D.G. ; Fink, S. ; Mautner, J. ; Delecluse, H.J.
Antibodies conjugated with viral antigens elicit a cytotoxic T cell response against primary CLL ex vivo.Anastasiadou, E. ; Stroopinsky, D. ; Alimperti, S. ; Jiao, A.L. ; Pyzer, A.R. ; Cippitelli, C. ; Pepe, G. ; Severa, M. ; Rosenblatt, J. ; Etna, M.P. ; Rieger, S. ; Kempkes, B. ; Coccia, E.M. ; Sui, S.J.H. ; Chen, C.S. ; Uccini, S. ; Avigan, D. ; Faggioni, A. ; Trivedi, P. ; Slack, F.J.
Epstein-Barr virus-encoded EBNA2 alters immune checkpoint PD-L1 expression by downregulating miR-34a in B-cell lymphomas.Bräuer, K. ; Brockers, K. ; Moneer, J. ; Feuchtinger, A. ; Wollscheid-Lengeling, E. ; Lengeling, A. ; Wolf, A.
Phylogenetic and genomic analyses of the ribosomal oxygenases Riox1 (No66) and Riox2 (Mina53) provide new insights into their evolution.Fiedler, L. ; Kellner, M. ; Oos, R. ; Böning, G. ; Ziegler, S. ; Bartenstein, P. ; Zeidler, R. ; Gildehaus, F.J. ; Lindner, S.
Fully automated production and characterization of 64Cu and proof-of-principle small-animal PET imaging using 64Cu-labelled CA XII targeting 6A10 fab.Saller, M.M. ; Huettl, R.E. ; Mayer, J.M. ; Feuchtinger, A. ; Krug, C. ; Holzbach, T. ; Volkmer, E.
Validation of a novel animal model for sciatic nerve repair with an adipose-derived stem cell loaded fibrin conduit.Lohöfer, F. ; Hoffmann, L. ; Buchholz, R. ; Huber, K. ; Glinzer, A. ; Kosanke, K. ; Feuchtinger, A. ; Aichler, M. ; Feuerecker, B. ; Kaissis, G. ; Rummeny, E.J. ; Höltke, C. ; Faber, C. ; Schilling, F. ; Botnar, R.M. ; Walch, A.K. ; Karst, U. ; Wildgruber, M.
Molecular imaging of myocardial infarction with Gadofluorine P – A combined magnetic resonance and mass spectrometry imaging approach.Gary, R. ; Aigner, M. ; Moi, S. ; Schaffer, S. ; Gottmann, A. ; Maas, S. ; Zimmermann, R. ; Zingsem, J. ; Strobel, J. ; Mackensen, A. ; Mautner, J. ; Moosmann, A. ; Gerbitz, A.
Clinical-grade generation of peptide-stimulated CMV/EBV-specific T cells from G-CSF mobilized stem cell grafts.von Neubeck, B. ; Gondi, G. ; Riganti, C. ; Pan, C. ; Parra Damas, A. ; Scherb, H. ; Ertürk, A. ; Zeidler, R.
An inhibitory antibody targeting carbonic anhydrase XII abrogates chemoresistance and significantly reduces lung metastases in an orthotopic breast cancer model in vivo.Schlott, F. ; Steubl, D. ; Ameres, S. ; Moosmann, A. ; Dreher, S. ; Heemann, U. ; Hösel, V. ; Busch, D.H. ; Neuenhahn, M.
Characterization and clinical enrichment of HLA-C*07:02-restricted Cytomegalovirus-specific CD8+ T cells.Rodriguez Camargo, D.C. ; Garg, D. ; Buday, K. ; Frankó, A. ; Rodriguez Camargo, A. ; Schmidt, F. ; Cox, S.J. ; Suladze, S. ; Haslbeck, M. ; Mideksa, Y.G. ; Gemmecker, G. ; Aichler, M. ; Mettenleiter, G. ; Schulz, M. ; Walch, A.K. ; Hrabě de Angelis, M. ; Feige, M.J. ; Sierra, C.A. ; Conrad, M. ; Tripsianes, K. ; Ramamoorthy, A. ; Reif, B.
hIAPP forms toxic oligomers in plasma.Gärtner, K. ; Battke, C. ; Dünzkofer, J. ; Hüls, C. ; von Neubeck, B. ; Kellner, M. ; Fiestas, E. ; Fackler, S. ; Lang, S. ; Zeidler, R.
Tumor-derived extracellular vesicles activate primary monocytes.Martin, L.K. ; Hollaus, A. ; Stahuber, A. ; Hübener, C. ; Fraccaroli, A. ; Tischer, J. ; Schub, A. ; Moosmann, A.
Cross-sectional analysis of CD8 T cell immunity to human herpesvirus 6B.Wilke, C. ; Braselmann, H. ; Hess J. ; Klymenko, S.V. ; Chumak, V.V. ; Zakhartseva, L.M. ; Bakhanova, E.V. ; Walch, A.K. ; Selmansberger, M. ; Samaga, D. ; Weber, P. ; Schneider, L. ; Fend, F. ; Bösmüller, H.C. ; Zitzelsberger, H. ; Unger, K.
A genomic copy number signature predicts radiation exposure in post-Chernobyl breast cancer.Fiedler, L. ; Kellner, M. ; Gosewisch, A. ; Oos, R. ; Böning, G. ; Lindner, S. ; Albert, N. ; Bartenstein, P. ; Reulen, H.J. ; Zeidler, R. ; Gildehaus, F.J.
Evaluation of 177Lu[Lu]-CHX-A″-DTPA-6A10 Fab as a radioimmunotherapy agent targeting carbonic anhydrase XII.Sarrach, S. ; Huang, Y. ; Niedermeyer, S. ; Hachmeister, M. ; Fischer, L. ; Gille, S. ; Pan, M. ; Mack, B. ; Kranz, G. ; Libl, D. ; Merl-Pham, J. ; Hauck, S.M. ; Paoluzzi Tomada, E. ; Kieslinger, M. ; Jeremias, I. ; Scialdone, A. ; Gires, O.
Spatiotemporal patterning of EpCAM is important for murine embryonic endo-And mesodermal differentiation.Engler, A. ; Rolando, C. ; Giachino, C. ; Saotome, I. ; Erni, A. ; Brien, C. ; Zhang, R. ; Zimber-Strobl, U. ; Radtke, F. ; Artavanis-Tsakonas, S. ; Louvi, A. ; Taylor, V.
Notch2 signaling maintains NSC quiescence in the murine ventricular-subventricular zone.Ghasemi, A. ; Mohammad, N. ; Mautner, J. ; Karsabet, M.T. ; Ardjmand, A. ; Moniri, R.
Immunization with recombinant FliD confers protection against Helicobacter pylori infection in mice.Frankó, A. ; Rodriguez Camargo, D.C. ; Böddrich, A. ; Garg, D. ; Rodriguez Camargo, A. ; Rathkolb, B. ; Janik, D. ; Aichler, M. ; Feuchtinger, A. ; Neff, F. ; Fuchs, H. ; Wanker, E.E. ; Reif, B. ; Häring, H.-U. ; Peter, A. ; Hrabě de Angelis, M.
Epigallocatechin gallate (EGCG) reduces the intensity of pancreatic amyloid fibrils in human islet amyloid polypeptide (hIAPP) transgenic mice.Sun, N. ; Wu, Y. ; Nanba, K. ; Sbiera, S. ; Kircher, S. ; Kunzke, T. ; Aichler, M. ; Berezowska, S. ; Reibetanz, J. ; Rainey, W.E. ; Fassnacht, M. ; Walch, A.K. ; Kroiss, M.
High resolution tissue mass spectrometry imaging reveals a refined functional anatomy of the human adult adrenal gland.Cirac, A. ; Stützle, S. ; Dieckmeyer, M. ; Adhikary, D. ; Moosmann, A. ; Körber, N. ; Bauer, T. ; Witter, K. ; Delecluse, H.J. ; Behrends, U. ; Mautner, J.
Epstein-Barr virus strain heterogeneity impairs human T-cell immunity.Dalke, C. ; Neff, F. ; Bains, S.K. ; Bright, S. ; Lord, D.J. ; Reitmeir, P. ; Rößler, U. ; Samaga, D. ; Unger, K. ; Braselmann, H. ; Wagner, F. ; Greiter, M. ; Gomolka, M. ; Hornhardt, S. ; Kunze, S. ; Kempf, S.J. ; Garrett, L. ; Hölter, S.M. ; Wurst, W. ; Rosemann, M. ; Azimzadeh, O. ; Tapio, S. ; Aubele, M. ; Theis, F.J. ; Hoeschen, C. ; Slijepcevic, P. ; Kadhim, M. ; Atkinson, M.J. ; Zitzelsberger, H. ; Kulka, U. ; Graw, J.
Lifetime study in mice after acute low-dose ionizing radiation: A multifactorial study with special focus on cataract risk.Absmaier, M. ; Napieralski, R. ; Schuster, T. ; Aubele, M. ; Walch, A.K. ; Magdolen, V. ; Dorn, J. ; Gross, E. ; Harbeck, N. ; Noske, A. ; Kiechle, M. ; Schmitt, M.
PITX2 DNA-methylation predicts response to anthracycline-based adjuvant chemotherapy in triple-negative breast cancer patients.Ingold, I. ; Berndt, C. ; Schmitt, S. ; Doll, S. ; Poschmann, G. ; Buday, K. ; Roveri, A. ; Peng, X. ; Porto Freitas, F. ; Seibt, T. ; Mehr, L. ; Aichler, M. ; Walch, A.K. ; Lamp, D. ; Jastroch, M. ; Miyamoto, S. ; Wurst, W. ; Ursini, F. ; Arnér, E.S.J. ; Fradejas-Villar, N. ; Schweizer, U. ; Zischka, H. ; Friedmann Angeli, J.P.F. ; Conrad, M.
Selenium utilization by GPX4 is required to prevent hydroperoxide-induced ferroptosis.Molatore, S. ; Kügler, A. ; Irmler, M. ; Wiedemann, T. ; Neff, F. ; Feuchtinger, A. ; Beckers, J. ; Robledo, M. ; Roncaroli, F. ; Pellegata, N.S.
Characterization of neuroendocrine tumors in heterozygous mutant MENX rats: A novel model of invasive medullary thyroid carcinoma.Aichler, M. ; Kunzke, T. ; Buck, A. ; Sun, N. ; Ackermann, M. ; Jonigk, D. ; Gaumann, A. ; Walch, A.K.
Molecular similarities and differences from human pulmonary fibrosis and corresponding mouse model: MALDI imaging mass spectrometry in comparative medicine.Wilke, C. ; Hess J. ; Klymenko, S.V. ; Chumak, V.V. ; Zakhartseva, L.M. ; Bakhanova, E.V. ; Feuchtinger, A. ; Walch, A.K. ; Selmansberger, M. ; Braselmann, H. ; Schneider, L. ; Pitea, A. ; Steinhilber, J. ; Fend, F. ; Bösmüller, H.C. ; Zitzelsberger, H. ; Unger, K.
Expression of miRNA-26b-5p and its target TRPS1 is associated with radiation exposure in post-Chernobyl breast cancer.Prade, V.M. ; Gundlach, H. ; Twardziok, S.O. ; Chapman, B. ; Tan, C.S. ; Langridge, P. ; Schulman, A.H. ; Stein, N. ; Waugh, R. ; Zhang, G. ; Platzer, M. ; Li, C. ; Spannagl, M. ; Mayer, K.F.X.
The pseudogenes of barley.Ingold, I. ; Berndt, C. ; Schmitt, S. ; Doll, S. ; Poschmann, G. ; Roveri, A. ; Peng, X. ; Freitas, F.P. ; Aichler, M. ; Jastroch, M. ; Ursini, F. ; Arner, E.S.J. ; Fradejas-Villar, N. ; Schweizer, U. ; Zischka, H. ; Friedmann Angeli, J.P.F. ; Conrad, M.
Selenium utilization by GPX4 was an evolutionary requirement to prevent hydroperoxide-induced ferroptosis.Klaeger, S. ; Heinzlmeir, S. ; Wilhelm, M. ; Polzer, H. ; Vick, B. ; Koenig, P.A. ; Reinecke, M. ; Ruprecht, B. ; Petzoldt, S. ; Meng, C. ; Zecha, J. ; Reiter, K. ; Qiao, H. ; Helm, D. ; Koch, H. ; Schoof, M. ; Canevari, G. ; Casale, E. ; Depaolini, S.R. ; Feuchtinger, A. ; Wu, Z. ; Schmidt, T. ; Rueckert, L. ; Becker, W. ; Huenges, J. ; Garz, A.K. ; Gohlke, B.O. ; Zolg, D.P. ; Kayser, G. ; Vooder, T. ; Preissner, R. ; Hahne, H. ; Tõnisson, N. ; Kramer, K. ; Götze, K. ; Bassermann, F. ; Schlegl, J. ; Ehrlich, H.C. ; Aiche, S. ; Walch, A.K. ; Greif, P.A. ; Schneider, S. ; Felder, E.R. ; Ruland, J. ; Médard, G. ; Jeremias, I. ; Spiekermann, K. ; Kuster, B.
The target landscape of clinical kinase drugs.Rodriguez Camargo, D.C. ; Korshavn, K.J. ; Jussupow, A. ; Raltchev, K. ; Goricanec, D. ; Fleisch, M. ; Sarkar, R. ; Xue, K. ; Aichler, M. ; Mettenleiter, G. ; Walch, A.K. ; Camilloni, C. ; Hagn, F. ; Reif, B. ; Ramamoorthy, A.
Stabilization and structural analysis of a membrane-associated hIAPP aggregation intermediate.Desbenoit, N. ; Walch, A.K. ; Spengler, B. ; Brunelle, A. ; Römpp, A.
Correlative mass spectrometry imaging, applying TOF-SIMS and AP-MALDI to a single tissue section.Jacobs, L. ; Habringer, S. ; Slawska, J. ; Huber, K. ; Hauf, E. ; Li, Z. ; Refaeli, Y. ; Schwaiger, M. ; Rudelius, M. ; Walch, A.K. ; Keller, U.
Functional imaging in combination with mutation status aids prediction of response to inhibiting B-cell receptor signaling in lymphoma.Gary, R. ; Aigner, M. ; Moosmann, A. ; Moi, S. ; Schaffer, S. ; Balzer, H.J. ; Maas, S. ; Strobel, J. ; Zimmermann, R. ; Zingsem, J. ; Kremer, A. ; Meintker, L. ; Mackensen, A. ; Gerbitz, A.
Adoptive transfer of CMV- and EBV-specific peptide-stimulated T cells after allogeneic stem cell transplantation: First results of a phase I/IIa clinical trial [AIT-MULTIVIR-01].Richter, A.S. ; Roolf, C. ; Sender, S. ; Sekora, A. ; Knbel, G. ; Vollmar, B. ; Jeremias, I. ; Escobar, M.H. ; Junghanss, C.
CK2 inhibition reduces cell proliferation in acute B-lymphoblastic leukemia cells in vitro and in vivo.Urban, C. ; Buck, A. ; Siveke, J.T. ; Lordick, F. ; Luber, B. ; Walch, A.K. ; Aichler, M.
PAXgene fixation enables comprehensive metabolomic and proteomic analyses of tissue specimens by MALDI MSI.Mümmler, C. ; Burgy, O. ; Hermann, S. ; Mutze, K. ; Günther, A. ; Königshoff, M.
Cell-specific expression of runt-related transcription factor 2 contributes to pulmonary fibrosis.Glaser, L.V. ; Rieger, S. ; Thumann, S. ; Beer, S. ; Kuklik-Roos, C. ; Martin, D.E. ; Maier, K.C. ; Harth-Hertle, M.L. ; Grüning, B. ; Backofen, R. ; Krebs, S. ; Blum, H. ; Zimmer, R. ; Erhard, F. ; Kempkes, B.
EBF1 binds to EBNA2 and promotes the assembly of EBNA2 chromatin complexes in B cells.Fichter, C.D. ; Przypadlo, C.M. ; Buck, A. ; Herbener, N. ; Riedel, B. ; Schäfer, L. ; Nakagawa, H. ; Walch, A.K. ; Reinheckel, T. ; Werner, M. ; Lassmann, S.
A new model system identifies EGFR/HER2 and HER2/HER3 heterodimers as potent inducers of oesophageal epithelial cell invasion.Link, E.K. ; Brandmüller, C. ; Suezer, Y. ; Ameres, S. ; Volz, A. ; Moosmann, A. ; Sutter, G. ; Lehmann, M.H.
A synthetic human cytomegalovirus pp65-IE1 fusion antigen efficiently induces and expands virus specific T cells.Ayoubian, H. ; Fröhlich, T. ; Pogodski, D. ; Flatley, A. ; Kremmer, E. ; Schepers, A. ; Feederle, R. ; Arnold, G.J. ; Grässer, F.A.
Antibodies against the mono-methylated arginine-glycine repeat (MMA-RG) of the Epstein-Barr virus nuclear antigen 2 (EBNA2) identify potential cellular proteins targeted in viral transformation.Koch, M. ; de Jong, J.S. ; Glatz, J. ; Symvoulidis, P. ; Lamberts, L.E. ; Adams, A.L.L. ; Kranendonk, M.E.G. ; van Scheltinga, A.T. ; Aichler, M. ; Jansen, L. ; de Vries, J. ; Lub-de Hooge, M. ; Schröder, C.P. ; Jorritsma-Smit, A. ; Linssen, M.D. ; de Boer, E. ; van der Vegt, B. ; Nagengast, W.B. ; Elias, S.G. ; Oliveira, S. ; Witkamp, A.J. ; Mali, W.P.Th.M. ; van der Wall, E. ; Garcia-Allende, P. ; van Diest, P.J. ; de Vries, E.G. ; Walch, A.K. ; van Dam, G.M. ; Ntziachristos, V.
Fluorescently labeled bevacizumab in human breast cancer: Defining the classification threshold.Brustel, J. ; Kirstein, N. ; Izard, F. ; Grimaud, C. ; Prorok, P. ; Cayrou, C. ; Schotta, G. ; Abdelsamie, A.S. ; Déjardin, J. ; Méchali, M. ; Baldacci, G. ; Sardet, C. ; Cadoret, J.C. ; Schepers, A. ; Julien, E.
Histone H4K20 tri-methylation at late-firing origins ensures timely heterochromatin replication.Schlecht, A. ; Leimbeck, S.V. ; Jägle, H. ; Feuchtinger, A. ; Tamm, E.R. ; Braunger, B.M.
Deletion of endothelial TGF-β signaling leads to choroidal neovascularization.Yang, F. ; Aubele, M. ; Walch, A.K. ; Gross, E. ; Napieralski, R. ; Zhao, S. ; Ahmed, N. ; Kiechle, M. ; Reuning, U. ; Dorn, J. ; Sweep, F.C. ; Magdolen, V. ; Schmitt, M.
Tissue kallikrein-related peptidase 4 (KLK4), a novel biomarker in triple-negative breast cancer.Kunzke, T. ; Balluff, B. ; Feuchtinger, A. ; Buck, A. ; Langer, R. ; Luber, B. ; Lordick, F. ; Zitzelsberger, H. ; Aichler, M. ; Walch, A.K.
Native glycan fragments detected by MALDI-FT-ICR mass spectrometry imaging impact gastric cancer biology and patient outcome.Lichtenegger, F.S. ; Deiser, K. ; Rothe, M. ; Krupka, C. ; Schnorfeil, F.M. ; Augsberger, C. ; Koehnke, T. ; Buecklein, V. ; Altmann, T. ; Moosmann, A. ; Brueggemann, M. ; Heemskerk, M.H.M. ; Wagner, B. ; Hiddemann, W. ; Bigalke, I. ; Kvalheitn, G. ; Subklewe, M.
Induction of antigen-specific T-cell responses through dendritic cell vaccination in AML: Results of a phase I/II trial and ex vivo enhancement by checkpoint blockade.Loebel, M. ; Eckey, M. ; Sotzny, F. ; Hahn, E.G. ; Bauer, S. ; Grabowski, P. ; Zerweck, J. ; Holenya, P. ; Hanitsch, L.G. ; Wittke, K. ; Borchmann, P. ; Rüffer, J.U. ; Hiepe, F. ; Ruprecht, K. ; Behrends, U. ; Meindl, C. ; Volk, H.D. ; Reimer, U. ; Scheibenbogen, C.
Serological profiling of the EBV immune response in Chronic Fatigue Syndrome using a peptide microarray.Albanese, M. ; Tagawa, T. ; Buschle, A. ; Hammerschmidt, W.
MicroRNAs of Epstein-Barr virus control innate and adaptive anti-viral immunity.Heckl, B. ; Carlet, M. ; Grunert, M. ; Vick, B. ; Roolf, C. ; Junghanss, C. ; Spiekermann, K. ; Hiddemann, W. ; Jeremias, I.
Adult primary acute leukemia samples with chromosomal translocations grow well in immunodeficient mice, but are difficult to transduce with lentiviruses.Altamura, S. ; Vegi, N. ; Hueltner, L. ; Schneider, M. ; Höppe, P. ; Schroeder, T. ; Canli, Ö. ; Greten, F.R. ; Aichler, M. ; Walch, A.K. ; Neff, F. ; Janik, D. ; Kuklik-Roos, C. ; Ladinig, C. ; Mysliwietz, J. ; Rathkolb, B. ; Buske, C. ; Conrad, M. ; Muckenthaler, M.U. ; Bornkamm, G.W.
Lack of the ferroptosis inhibitor GPX4 in erythroid cells causes a block in reticulocyte maturation and a hypoxic signature with impaired hepcidin regulation.Düwel, S. ; Hundshammer, C. ; Gersch, M. ; Feuerecker, B. ; Steiger, K. ; Buck, A. ; Walch, A.K. ; Haase, A. ; Glaser, S.J. ; Schwaiger, M. ; Schilling, F.
Imaging of pH in vivo using hyperpolarized 13C-labelled zymonic acid.Hachmöller, O. ; Aichler, M. ; Schwamborn, K. ; Lutz, L. ; Werner, M. ; Sperling, M. ; Walch, A.K. ; Karst, U.
Investigating the influence of standard staining procedures on the copper distribution and concentration in Wilson's disease liver samples by laser ablation-inductively coupled plasma-mass spectrometry.David, A. ; Arnaud, N. ; Fradet, M. ; Lascaux, H. ; Ouk-Martin, C. ; Gachard, N. ; Zimber-Strobl, U. ; Feuillard, J. ; Faumont, N.
c-Myc dysregulation is a co-transforming event for nuclear factor-κB activated B cells.Medina, A.M. ; Vierkotten, S. ; Lehmann, M. ; Wagner, D. ; Baarsma, H. ; Höfer, T. ; Frankerberger, M. ; Behr, J. ; Aichler, M. ; Walch, A. ; Königshoff, M.
Wnt5a is secreted by extracellular vesicles in pulmonary fibrosis and increases fibroblasts proliferation.Aichler, M. ; Borgmann, D.M. ; Krumsiek, J. ; Buck, A. ; MacDonald, P.E. ; Fox, J.E.M. ; Lyon, J. ; Light, P.E. ; Keipert, S. ; Jastroch, M. ; Feuchtinger, A. ; Müller, N.S. ; Sun, N. ; Palmer, A. ; Alexandrov, T. ; Hrabě de Angelis, M. ; Neschen, S. ; Tschöp, M.H. ; Walch, A.K.
N-acyl taurines and acylcarnitines cause an imbalance in insulin synthesis and secretion provoking β cell dysfunction in type 2 diabetes.Barthels, C. ; Ogrinc, A. ; Steyer, V. ; Meier, S. ; Simon, F. ; Wimmer, M. ; Blutke, A. ; Straub, T. ; Zimber-Strobl, U. ; Lutgens, E. ; Marconi, P. ; Ohnmacht, C. ; Garzetti, D. ; Stecher, B. ; Brocker, T.
CD40-signalling abrogates induction of RORγt+ Treg cells by intestinal CD103+ DCs and causes fatal colitis.Feederle, R. ; Schepers, A.
Antibodies specific for nucleic acid modifications.Arlt, W. ; Lang, K. ; Sitch, A.J. ; Dietz, A.S. ; Rhayem, Y. ; Bancos, I. ; Feuchtinger, A. ; Chortis, V. ; Gilligan, L.C. ; Ludwig, P. ; Riester, A. ; Asbach, E. ; Hughes, B.A. ; O'Neil, D.M. ; Bidlingmaier, M. ; Tomlinson, J.W. ; Hassan-Smith, Z.K. ; Rees, D.A. ; Adolf, C. ; Hahner, S. ; Quinkler, M. ; Dekkers, T. ; Deinum, J. ; Biehl, M. ; Keevil, B.G. ; Shackleton, C.H.L. ; Deeks, J.J. ; Walch, A.K. ; Beuschlein, F. ; Reincke, M.
Steroid metabolome analysis reveals prevalent glucocorticoid excess in primary aldosteronism.Finkenzeller, C. ; Carlet, M. ; Vosberg, S. ; Neumann, M. ; Riecken, K. ; Cornils, K. ; Fehse, B. ; Baldus, C.D. ; Greif, P.A. ; Jeremias, I.
Clones with and without sensitivity towards treatment in vivo co-exist within a single sample of a patient with ALL.Vergalli, J. ; Carlet, M. ; Hoffmann, T. ; Roth, M. ; Zuber, J. ; Jeremias, I.
XIAP is an attractive therapeutic target for all as validated in innovative genetically rngineered patient-derived xenograft models.Koczian, F. ; Vomacka, J. ; Vick, B. ; Hettich, B. ; Kazmaier, U. ; Sieber, S.A. ; Jeremias, I. ; Vollmar, A. ; Braig, S.
Targeting the ER-mitochondrial interface of cell death sensitizes leukemia cells towards cytostatics.Vick, B. ; Holdt, L.M. ; Hiddemann, W.R. ; Spiekermann, K. ; Jeremias, I.
Modeling AML standard induction chemotherapy in the PDX mouse model.Heckl, B. ; Carlet, M. ; Grunert, M. ; Vick, B. ; Roolf, C. ; Junghanss, C. ; Spiekermann, K. ; Hiddemann, W.R. ; Jeremias, I.
Primary adult acute lymphoblastic leukemic cells reliably engraft and grow in immunodeficient mice.Oezdemir, E. ; Ziegenhain, C. ; Panzer-Gruenmayer, R. ; Enard, W. ; Jeremias, I.
A preclinical PDX model for patients` minimal residual disease in ALL.Ebinger, S. ; Liu, W. ; Tiedt, S. ; Alves, C.C. ; Jeremias, I.
A rare population of drug resistant, dormant stem cells exists in patients' acute lymphoblastic leukemia growing in mice.Bagnoli, J. ; Ziegenhain, C. ; Vieth, B. ; Parekh, S. ; Vick, B. ; Jeremias, I. ; Hellmann, I. ; Enard, W.
Transcriptional heterogeneity in AML - evolution of gene expression in patient derived xenografts.Valtierra-Gutierrez, I.A. ; Farre-Orteu, A. ; Richter, M. ; Greif, P.A. ; Ziegenhain, C. ; Jeremias, I. ; Metzeler, K. ; Spiekermann, K. ; Enard, W. ; Hellmann, I.
Detection of single-nucleotide variants in acute myeloid leukemia (AML) from bulk and single-cell RNA sequencing.Van Deun, J. ; Mestdagh, P. ; Agostinis, P. ; Akay, Ö. ; Anand, S. ; Anckaert, J. ; Martinez, Z.A. ; Baetens, T. ; Beghein, E. ; Bertier, L. ; Berx, G. ; Boere, J. ; Boukouris, S. ; Bremer, M. ; Buschmann, D. ; Byrd, J.B. ; Casert, C. ; Cheng, L. ; Cmoch, A. ; Daveloose, D. ; De Smedt, E. ; Demirsoy, S. ; Depoorter, V. ; Dhondt, B. ; Driedonks, T.A.P. ; Dudek, A. ; Elsharawy, A. ; Floris, I. ; Foers, A.D. ; Gärtner, K. ; Garg, A.D. ; Geeurickx, E. ; Gettemans, J. ; Ghazavi, F. ; Giebel, B. ; Kormelink, T.G. ; Hancock, G. ; Helsmoortel, H. ; Hill, A.F. ; Hyenne, V. ; Kalra, H. ; Kim, D. ; Kowal, J. ; Kraemer, S. ; Leidinger, P. ; Leonelli, C. ; Liang, Y. ; Lippens, L. ; Liu, S. ; Lo Cicero, A. ; Martin, S. ; Mathivanan, S. ; Mathiyalagan, P. ; Matusek, T. ; Milani, G. ; Monguió-Tortajada, M. ; Mus, L.M. ; Muth, D.C. ; Németh, A. ; Nolte-'T Hoen, E.N.M. ; O'Driscoll, L. ; Palmulli, R. ; Pfaffl, M.W. ; Primdal-Bengtson, B. ; Romano, E. ; Rousseau, Q. ; Sahoo, S. ; Sampaio, N. ; Samuel, M.A. ; Scicluna, B.P. ; Soen, B. ; Steels, A. ; Swinnen, J.V. ; Takatalo, M. ; Thaminy, S. ; Théry, C. ; Tulkens, J. ; Van Audenhove, I. ; Van Der Grein, S. ; Van Goethem, A. ; Van Herwijnen, M.J. ; Van Niel, G. ; Van Roy, N. ; Van Vliet, A.R. ; Vandamme, N. ; Vanhauwaert, S. ; Vergauwen, G. ; Verweij, F.
EV-TRACK: Transparent reporting and centralizing knowledge in extracellular vesicle research.Knüppel, L. ; Ishikawa, Y. ; Aichler, M. ; Heinzelmann, K. ; Hatz, R. ; Behr, J. ; Walch, A.K. ; Bächinger, H.P. ; Eickelberg, O. ; Staab-Weijnitz, C.A.
A novel antifibrotic mechanism of nintedanib and pirfenidone: Inhibition of collagen fibril assembly.Dislich, B. ; Stein, A. ; Seiler, C.A. ; Kröll, D. ; Berezowska, S. ; Zlobec, I. ; Galvan, J.A. ; Slotta-Huspenina, J. ; Walch, A.K. ; Langer, R.
Expression patterns of programmed death-ligand 1 in esophageal adenocarcinomas: Comparison between primary tumors and metastases.Echtler, K. ; Konrad, I. ; Lorenz, M. ; Schneider, S. ; Hofmaier, S. ; Plenagl, F. ; Stark, K. ; Czermak, T. ; Tirniceriu, A. ; Eichhorn, M.E. ; Walch, A.K. ; Enders, G. ; Massberg, S. ; Schulz, C.
Platelet GPIIb supports initial pulmonary retention but inhibits subsequent proliferation of melanoma cells during hematogenic metastasis.Rodriguez Camargo, D.C. ; Tripsianes, K. ; Buday, K. ; Frankó, A. ; Göbl, C. ; Hartlmüller, C. ; Sarkar, R. ; Aichler, M. ; Mettenleiter, G. ; Schulz, M. ; Böddrich, A. ; Erck, C. ; Martens, H. ; Walch, A.K. ; Madl, T. ; Wanker, E.E. ; Conrad, M. ; Hrabě de Angelis, M. ; Reif, B.
The redox environment triggers conformational changes and aggregation of hIAPP in Type II Diabetes.Schober, T. ; Magg, T. ; Laschinger, M. ; Rohlfs, M. ; Linhares, N.D. ; Puchalka, J. ; Weisser, T. ; Fehlner, K. ; Mautner, J. ; Walz, C. ; Hussein, K. ; Jaeger, G. ; Kammer, B. ; Schmid, I. ; Bahia, M. ; Pena, S.D.J. ; Behrends, U. ; Belohradsky, B.H. ; Klein, C. ; Hauck, F.
A human immunodeficiency syndrome caused by mutations in CARMIL2.Shumilov, A. ; Tsai, M.H. ; Schlosser, Y.T. ; Kratz, A.S. ; Bernhardt, K. ; Fink, S. ; Mizani, T. ; Lin, X. ; Jauch, A. ; Mautner, J. ; Kopp-Schneider, A. ; Feederle, R. ; Hoffmann, I. ; Delecluse, H.J.
Epstein-Barr virus particles induce centrosome amplification and chromosomal instability.Frankó, A. ; Neschen, S. ; Rozman, J. ; Rathkolb, B. ; Aichler, M. ; Feuchtinger, A. ; Brachthäuser, L. ; Neff, F. ; Kovarova, M. ; Wolf, E. ; Fuchs, H. ; Häring, H.-U. ; Peter, A. ; Hrabě de Angelis, M.
Bezafibrate ameliorates diabetes via reduced steatosis and improved hepatic insulin sensitivity in diabetic TallyHo mice.Ghosh, S. ; Hönscheid, A. ; Dückers, G. ; Ginzel, S. ; Gohlke, H. ; Gombert, M. ; Kempkes, B. ; Klapper, W. ; Kuhlen, M. ; Laws, H.J. ; Linka, R.M. ; Meisel, R. ; Niehues, T. ; Schindler, D. ; Schuster, F.R. ; Speckmann, C. ; Borkhardt, A.
Human RAD52: a novel player in DNA repair in cancer and immunodeficiency.Buck, A. ; Aichler, M. ; Huber, K. ; Walch, A.K.
In situ metabolomics in cancer by mass spectrometry imaging.Göllner, S. ; Oellerich, T. ; Agrawal-Singh, S. ; Schenk, T. ; Klein, H. ; Rohde, C. ; Pabst, C. ; Sauer, T. ; Lerdrup, M. ; Tavor, S. ; Stoelzel, F. ; Herold, S. ; Ehninger, G. ; Koehler, G. ; Pan, K. ; Urlaub, H. ; Serve, H. ; Dugas, M. ; Spiekermann, K. ; Vick, B. ; Jeremias, I. ; Berdel, W.E. ; Hansen, K. ; Zelent, A. ; Wickenhauser, C. ; Mueller, L.P. ; Thiede, C. ; Mueller-Tidow, C.
Loss of the histone methyltransferase EZH2 induces resistance to multiple drugs in acute myeloid leukemia.Ma, X. ; van Phi, V. ; Kimm, M.A. ; Prakash, J. ; Kessler, H. ; Kosanke, K. ; Feuchtinger, A. ; Aichler, M. ; Gupta, A. ; Rummeny, E.J. ; Eisenblätter, M. ; Siveke, J. ; Walch, A.K. ; Braren, R. ; Ntziachristos, V. ; Wildgruber, M.
Integrin-targeted hybrid fluorescence molecular tomography/X-ray computed tomography for imaging tumor progression and early response in non-small cell lung cancer.Zhao, S. ; Dorn, J. ; Napieralski, R. ; Walch, A.K. ; Diersch, S. ; Kotzsch, M. ; Ahmed, N. ; Hooper, J. ; Kiechle, M. ; Schmitt, M. ; Magdolen, V.
Plasmin(Ogen) serves as a favorable biomarker for prediction of survival in advanced high-grade serous ovarian cancer.Koch, M. ; de Jong, J.S. ; Glatz, J. ; Symvoulidis, P. ; Lamberts, L.E. ; Adams, A.L.L. ; Kranendonk, M.E.G. ; Terwisscha van Scheltinga, A.G. ; Aichler, M. ; Jansen, L. ; de Vries, J. ; Lub-de, Hoog, M.N. ; Schröder, C.P. ; Jorritsma-Smit, A. ; Linssen, M.D. ; de Boer, E. ; van der Vegt, B. ; Nagengast, W.B. ; Elisas,S.G. ; Oliveira, S. ; Witkamp, A.J. ; Mali, W.P.Th.M. ; van der Wall, E. ; Gracia-Allende, P.B. ; van Diest, P.J. ; de Vries, E.G. ; Walch, A.K. ; van Dam, G.M. ; Ntziachristos, V.
Threshold analysis and biodistribution of fluorescently labeled bevacizumab in human breast cancer.Doll, S. ; Proneth, B. ; Tyurina, A.A. ; Panzilius, E. ; Kobayashi, S. ; Ingold, I. ; Irmler, M. ; Beckers, J. ; Aichler, M. ; Walch, A.K. ; Prokisch, H. ; Trümbach, D. ; Mao, G. ; Qu, F. ; Bayir, H. ; Füllekrug, J. ; Scheel, C. ; Wurst, W. ; Schick, J. ; Kagan, V.E. ; Friedmann Angeli, J.P.F. ; Conrad, M.
ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition.Ebinger, S. ; Özdemir, E.Z. ; Ziegenhain, C. ; Tiedt, S. ; Castro Alves, C. ; Grunert, M. ; Dworzak, M. ; Lutz, C. ; Turati, V.A. ; Enver, T. ; Horny, H.-P. ; Sotlar, K. ; Parekh, S. ; Spiekermann, K. ; Hiddemann, W. ; Schepers, A. ; Polzer, B. ; Kirsch, S. ; Hoffmann, M. ; Knapp, B. ; Hasenauer, J. ; Pfeifer, H. ; Panzer-Grümayer, R. ; Enard, W. ; Gires, O. ; Jeremias, I.
Characterization of rare, dormant, and therapy-resistant cells in acute lymphoblastic leukemia.Luber, B. ; Keller, S. ; Zwingenberger, G. ; Ebert, K. ; Maier, D. ; Geier, B. ; Theis, F.J. ; Hasenauer, J. ; Huge, S. ; Meyer-Hermann, M. ; Dehghany, J. ; Walch, A.K. ; Aichler, M. ; Lordick, F. ; Haffner, I.
Identification of predictive response and resistance factors to targeted therapy in gastric cancer using a systems medicine approach.Vergalli, J. ; Carletl, M. ; Hoffmann, T. ; Rothe, M. ; Zuber, J. ; Jeremias, I.
X-Linked inhibitor of apoptosis protein (XIAP) exhibits an essential role of patients' acute lymphoblastic leukemia cells growing in vivo.Jacobsen, C. ; Kopp, N. ; Layer, J. ; Redd, R.A. ; Tschuri, S. ; Haebe, S. ; van Bodegom, D. ; Bird, L. ; Christie, A.L. ; Christodoulou, A.N. ; Saur, A. ; Tivey, T. ; Zapf, S.S. ; Bararia, D. ; Zimber-Strobl, U. ; Rodig, S.J. ; Weigert, O. ; Weinstock, D.M.
HSP90 inhibition overcomes ibrutinib resistance in mantle cell lymphoma.Habringer, S. ; Herhaus, P. ; Schottelius, M. ; Istvanffy, R. ; Goetze, K. ; Oostendorp, R. ; Grigoleit, G.U. ; Lapa, C. ; Jeremias, I. ; Schwaiger, M. ; Peschel, C. ; Wester, H.-J. ; Keller, U.
CXCR4-directed peptide receptor radiotherapy with 177Lu-Pentixather effectively clears leukemia in patient-derived xenografts.Lichtenedger, F.S. ; Deiser, K. ; Rothe, M. ; Krupka, C. ; Schnorfeil, F.M. ; Augsberger, C. ; Koehnke, T. ; Buecklein, V. ; Altmann, T. ; Moosmann, A. ; Brueggemann, M. ; Heemskerk, M.H.M. ; Wagner, B. ; Hiddemann, W.R. ; Bigalke, I. ; Kvalheim, G. ; Subklewe, M.
Induction of antigen-specific T-cell responses through dendritic cell vaccination in AML: results of a phase I/II trial and ex vivo enhancement by checkpoint blockade.Abdelmoula, W.M. ; Balluff, B. ; Englert, S. ; Dijkstra, J. ; Reinders, M.J.T. ; Walch, A.K. ; McDonnell, L.A. ; Lelieveldt, B.P.F.
Data-driven identification of prognostic tumor subpopulations using spatially mapped t-SNE of mass spectrometry imaging data.Schenck, T.L. ; Lin, S. ; Stewart, J.K. ; Koban, K.C. ; Aichler, M. ; Rezaeian, F. ; Giunta, R.E.
Sensory reanimation of the hand by transfer of the superficial branch of the radial nerve to the median and ulnar nerve.Wittmann, A. ; Grimm, M. ; Scherthan, H. ; Horsch, M. ; Beckers, J. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Ford, S.J. ; Burton, N.C. ; Razansky, D. ; Trümbach, D. ; Aichler, M. ; Walch, A.K. ; Calzada-Wack, J. ; Neff, F. ; Wurst, W. ; Hartmann, T. ; Floß, T.
Sphingomyelin synthase 1 is essential for male fertility in mice.Albanese, M. ; Tagawa, T. ; Bouvet, M. ; Maliqi, L. ; Lutter, D. ; Hoser, J.D.S. ; Hastreiter, M. ; Hayes, M. ; Sugden, B. ; Martin, L. ; Moosmann, A. ; Hammerschmidt, W.
Epstein-Barr virus microRNAs reduce immune surveillance by virus-specific CD8+ T cells.Oezdemir, E. ; Ebinger, S. ; Tiedt, S. ; Alves, C.C. ; Ziegenhain, C. ; Enard, W. ; Schepers, A. ; Jeremias, I.
A rare subpopulation of dormant, drug resistant stem cells in all mimics cells of minimal residual disease.Vergalli, J. ; Carlet, M. ; Hoffmann, T. ; Roth, M. ; Zuber, J. ; Jeremias, I.
Novel genetically engineered patient-derived xenograft (GEPDX) models reveal that xiap plays an essential role for patients´all growing in mice.Feuchtinger, A. ; Walch, A.K. ; Dobosz, M.
Deep tissue imaging: A review from a preclinical cancer research perspective.Tagawa, T. ; Albanese, M. ; Bouvet, M. ; Moosmann, A. ; Mautner, J. ; Heissmeyer, V. ; Zielinski, C. ; Lutter, D. ; Hoser, J.D.S. ; Hastreiter, M. ; Hayes, M. ; Sugden, B. ; Hammerschmidt, W.
Epstein-Barr viral miRNAs inhibit antiviral CD4+ T cell responses targeting IL-12 and peptide processing.Vincent-Fabert, C. ; Arnaud, N. ; Zimber-Strobl, U. ; Feuillard, J. ; Faumont, N.
The immune surveillance constraints B Cell lymphomas with continuous CD40 signaling to an indolent phenotype.Huber, M. ; Mall, R. ; Braselmann, H. ; Feuchtinger, A. ; Molatore, S. ; Lindner, K. ; Walch, A.K. ; Gross, E. ; Schmitt, M. ; Falkenberg, N. ; Aubele, M.
uPAR enhances malignant potential of triple-negative breast cancer by directly interacting with uPA and IGF1R.Gamrekelashvili, J. ; Giagnorio, R. ; Jussofie, J. ; Soehnlein, O. ; Duchene, J. ; Briseño, C.G. ; Ramasamy, S.K. ; Krishnasamy, K. ; Limbourg, A. ; Kapanadze, T. ; Ishifune, C. ; Hinkel, R. ; Radtke, F. ; Strobl, L.J. ; Zimber-Strobl, U. ; Napp, L.C. ; Bauersachs, J. ; Haller, H. ; Yasutomo, K. ; Kupatt, C. ; Murphy, K.M. ; Adams, R.H. ; Weber, C. ; Limbourg, F.P.
Regulation of monocyte cell fate by blood vessels mediated by Notch signalling.Stark, K. ; Philippi, V. ; Stockhausen, S. ; Busse, J. ; Antonelli, A. ; Miller, M. ; Schubert, I. ; Hoseinpour, P. ; Chandraratne, S. ; von Brühl, M.L. ; Gärtner, F. ; Lorenz, M. ; Agresti, A. ; Coletti, R. ; Antoine, D.J. ; Heermann, R. ; Jung, K. ; Reese, S. ; Laitinen, I. ; Schwaiger, M. ; Walch, A.K. ; Sperandio, M. ; Nawroth, P.P. ; Reinhardt, C. ; Jäckel, S. ; Bianchi, M.E. ; Massberg, S.
Disulfide HMGB1 derived from platelets coordinates venous thrombosis in mice.Chekkoury, A. ; Nunes, A. ; Gateau, J. ; Symvoulidis, P. ; Feuchtinger, A. ; Bézière, N. ; Ovsepian, S.V. ; Walch, A.K. ; Ntziachristos, V.
High-resolution multispectral optoacoustic tomography of the vascularization and constitutive hypoxemia of cancerous tumors.Daschkey, S. ; Bienemann, K. ; Schuster, V. ; Kreth, H.W. ; Linka, R.M. ; Hönscheid, A. ; Fritz, G. ; Johannes, C. ; Fleckenstein, B. ; Kempkes, B. ; Gombert, M. ; Ginzel, S. ; Borkhardt, A.
Fatal lymphoproliferative disease in two siblings lacking functional FAAP24.Ly, A. ; Buck, A. ; Balluff, B. ; Sun, N. ; Gorzolka, K. ; Feuchtinger, A. ; Janssen, K.P. ; Kuppen, P.J. ; van de Velde, C.J. ; Weirich, G. ; Erlmeier, F. ; Langer, R. ; Aubele, M. ; Zitzelsberger, H. ; McDonnell, L.A. ; Aichler, M. ; Walch, A.K.
High-mass-resolution MALDI mass spectrometry imaging of metabolites from formalin-fixed paraffin-embedded tissue.Mendler, C.T. ; Feuchtinger, A. ; Heid, I. ; Aichler, M. ; D'Alessandria, C. ; Pirsig, S. ; Blechert, B. ; Wester, H.J. ; Braren, R. ; Walch, A.K. ; Skerra, A. ; Schwaiger, M.
Tumor uptake of anti-CD20 Fabs depends on tumor perfusion.Hubmann, M. ; Fritsch, S. ; Zoellner, A.K. ; Prevalsek, D. ; Engel, N. ; Bücklein, V.L. ; Mumm, F. ; Schulz, C. ; Stemmler, H.J. ; Jäger, G. ; Ledderose, G. ; Kolb, H.J. ; Hausmann, A. ; Hiddemann, W. ; Moosmann, A. ; Tischer, J.
Occurrence, risk factors and outcome of adenovirus infection in adult recipients of allogeneic hematopoietic stem cell transplantation.Bader, E. ; Migliorini, A. ; Gegg, M. ; Moruzzi, N. ; Gerdes, J.M. ; Roscioni, S. ; Bakhti, M. ; Brandl, E. ; Irmler, M. ; Beckers, J. ; Aichler, M. ; Feuchtinger, A. ; Leitzinger, C. ; Zischka, H. ; Wang-Sattler, R. ; Jastroch, M. ; Tschöp, M.H. ; Machicao, F. ; Staiger, H. ; Häring, H.-U. ; Chmelova, H. ; Chouinard, J.A. ; Oskolkov, N. ; Korsgren, O. ; Speier, S. ; Lickert, H.
Identification of proliferative and mature β-cells in the islets of Langerhans.Mall, S. ; Yusufi, N. ; Wagner, R. ; Klar, R. ; Bianchi, H. ; Steiger, K. ; Straub, M. ; Audehm, S. ; Laitinen, I. ; Aichler, M. ; Peschel, C. ; Ziegler, S. ; Mustafa, M. ; Schwaiger, M. ; D'Alessandria, C. ; Krackhardt, A.M.
Immuno-PET imaging of engineered human T cells in tumors.Huber, M. ; Falkenberg, N. ; Hauck, S.M. ; Priller, M. ; Braselmann, H. ; Feuchtinger, A. ; Walch, A.K. ; Schmitt, M. ; Aubele, M.
Cyr61 and YB-1 are novel interacting partners of uPAR and elevate the malignancy of triple-negative breast cancer.Frankó, A. ; Huypens, P. ; Neschen, S. ; Irmler, M. ; Rozman, J. ; Rathkolb, B. ; Neff, F. ; Prehn, C. ; Dubois, G. ; Baumann, M. ; Massinger, R. ; Gradinger, D. ; Przemeck, G.K.H. ; Repp, B. ; Aichler, M. ; Feuchtinger, A. ; Schommers, P. ; Stöhr, O. ; Sanchez-Lasheras, C. ; Adamski, J. ; Peter, A. ; Prokisch, H. ; Beckers, J. ; Walch, A.K. ; Fuchs, H. ; Wolf, E. ; Schubert, M. ; Wiesner, R.J. ; Hrabě de Angelis, M.
Bezafibrate improves insulin sensitivity and metabolic flexibility in STZ-treated diabetic mice.Vitenshtein, A. ; Weisblum, Y. ; Hauka, S. ; Halenius, A. ; Oiknine-Djian, E. ; Tsukerman, P. ; Bauman, Y. ; Bar-On, Y. ; Stern-Ginossar, N. ; Enk, J. ; Ortenberg, R. ; Tai, J. ; Markel, G. ; Blumberg, R.S. ; Hengel, H. ; Jonjic, S. ; Wolf, D.G. ; Adler, H. ; Kammerer, R. ; Mandelboim, O.
CEACAM1-mediated inhibition of virus production.Krupka, C. ; Kufer, P. ; Kischel, R. ; Zugmaier, G. ; Koehnke, T. ; Lichtenegger, F.S. ; Altmann, T. ; Spiekermann, K. ; Vick, B. ; Jeremias, I. ; Hiddemann, W. ; Riethmueller, G. ; Subklewe, M.
Characterization of covariables modulating CD33/CD3 BITE antibody construct mediated cytotoxicity against primary AML cells.Lichtenegger, F.S. ; Schnorfeil, F.M. ; Koehnke, T. ; Altmann, T. ; Buecklein, V. ; Moosmann, A. ; Brueggemann, M. ; Wagner, B. ; Hiddemann, W. ; Bigalke, I. ; Kvalheim, G. ; Subklewe, M.
Next-generation dendritic cell vaccination in postremission therapy of AML: Results of a clinical phase I trial.Cassese, A. ; Ellis, S. ; Ogrinc Potočnik, N. ; Burgermeister, E. ; Ebert, M. ; Walch, A.K. ; van den Maagdenberg, A.M. ; McDonnell, L.A. ; Heeren, R.M. ; Balluff, B.
Spatial autocorrelation in mass spectrometry imaging.Dietzel, S. ; Hermann, S. ; Kugel, Y. ; Sellner, S. ; Uhl, B. ; Hirn, S. ; Krombach, F. ; Rehberg, M.
Multiphoton microscopy of nonfluorescent nanoparticles in vitro and in vivo.Buck, A. ; Balluff, B. ; Voss, A. ; Langer, R. ; Zitzelsberger, H. ; Aichler, M. ; Walch, A.K.
How suitable is MALDI-TOF for metabolite imaging from clinical formalin-fixed and paraffin-embedded tissue samples in comparison to MALDI-FT-ICR mass spectrometry?Dorn, J. ; Yassouridis, A. ; Walch, A.K. ; Diamandis, E.P. ; Schmitt, M. ; Kiechle, M. ; Wang, P. ; Drecoll, E. ; Schmalfeldt, B. ; Loessner, D. ; Kotzsch, M. ; Magdolen, V.
Assessment of kallikrein-related peptidase 5 (KLK5) protein expression in tumor tissue of advanced ovarian cancer patients by immunohistochemistry and ELISA: Correlation with clinical outcome.Townsend, E.C. ; Murakami, M.A. ; Christodoulou, A.N. ; Christie, A.L. ; Koster, J. ; DeSouza, T.A. ; Morgan, E.A. ; Kallgren, S.P. ; Liu, H. ; Wu, S.C. ; Plana, O. ; Montero, J. ; Stevenson, K.E. ; Rao, P. ; Vadhi, R. ; Andreeff, M. ; Armand, P. ; Ballen, K.K. ; Barzaghi-Rinaudo, P. ; Cahill, S. ; Clark, R.A. ; Cooke, V.G. ; Davids, M.S. ; DeAngelo, D.J. ; Dorfman, D.M. ; Eaton, H. ; Ebert, B.L. ; Etchin, J. ; Firestone, B. ; Fisher, D.C. ; Freedman, A.S. ; Galinsky, I.A. ; Gao, H. ; Garcia, J.S. ; Garnache-Ottou, F. ; Graubert, T.A. ; Gutierrez, A. ; Halilovic, E. ; Harris, M.H. ; Herbert, Z.T. ; Horwitz, S.M. ; Inghirami, G. ; Intlekoffer, A.M. ; Ito, M. ; Izraeli, S. ; Jacobsen, E.D. ; Jacobson, C.A. ; Jeay, S. ; Jeremias, I. ; Kelliher, M.A. ; Koch, R. ; Konopleva, M. ; Kopp, N. ; Kornblau, S.M. ; Kung, A.L. ; Kupper, T.S. ; LaBoeuf, N. ; LaCasce, A.S. ; Lees, E. ; Li, L.S. ; Look, A.T. ; Murakami, M. ; Muschen, M. ; Neuberg, D. ; Ng, S.Y. ; Odejide, O.O. ; Orkin, S.H. ; Paquette, R.R. ; Place, A.E. ; Roderick, J.E. ; Ryan, J.A. ; Sallan, S.E. ; Shoji, B. ; Silverman, L.B. ; Soiffer, R.J. ; Steensma, D.P. ; Stegmaier, K. ; Stone, R.M. ; Tamburini, J. ; Thorner, A.R. ; van Hummelen, P. ; Wadleigh, M. ; Wiesmann, M. ; Weng, A.P. ; Wuerthner, J.U. ; Williams, D.A. ; Wollison, B.M. ; Lane, A.A. ; Letai, A.G. ; Bertagnolli, M.M. ; Ritz, J. ; Brown, M. ; Long, H. ; Aster, J.C. ; Shipp, M.A. ; Griffin, J.D. ; Weinstock, D.M.
The public repository of xenografts enables discovery and randomized phase II-like trials in mice.Brenke, J.K. ; Salmina, E.S. ; Ringelstetter, L. ; Dornauer, S. ; Kuzikov, M. ; Rothenaigner, I. ; Schorpp, K.K. ; Giehler, F. ; Gopalakrishnan, J. ; Kieser, A. ; Gul, S. ; Tetko, I.V. ; Hadian, K.
Identification of small-molecule frequent hitters of glutathione S-transferase-glutathione interaction.Hachmöller, O. ; Aichler, M. ; Schwamborn, K. ; Lutz, L. ; Werner, M. ; Sperling, M. ; Walch, A.K. ; Karst, U.
Element bioimaging of liver needle biopsy specimens from patients with Wilson's disease by laser ablation-inductively coupled plasma-mass spectrometry.Sattler, C. ; Steer, B. ; Adler, H.
Multiple lytic origins of replication are required for optimal gammaherpesvirus fitness in vitro and in vivo.Trajkovic-Arsic, M. ; Kalideris, E. ; Sun, N. ; Feuchtinger, A. ; Gupta, A. ; Aichler, M. ; Schmid, R.M. ; Walch, A.K. ; Siveke, J.T.
Identification of metabolic changes in pancreatic ductal adenocarcinoma.Haffner, I. ; Luber, B. ; Maier, D. ; Geier, B. ; Theis, F.J. ; Meyer-Hermann, M. ; Walch, A.K. ; Kretzschmar, A.K. ; von Weikersthal, L.F. ; Knorrenschild, J.R. ; Schierle, K. ; Wittekind, C. ; Lordick, F.
Clinical validation of response and resistance factor candidates to targeted therapy in Gastric Cancer (GC).Hachmöller, O. ; Buzanich, A.G. ; Aichler, M. ; Radtke, M. ; Dietrich, D. ; Schwamborn, K. ; Lutz, L. ; Werner, M. ; Sperling, M. ; Walch, A.K. ; Karst, U.
Elemental bioimaging and speciation analysis for the investigation of Wilson's disease using μXRF and XANES.Dislich, B. ; Stein, A. ; Seiler, C.A. ; Walch, A.K. ; Berezowska, S. ; Zlobec, I. ; Galvan, J.A. ; Langer, R.
Low frequency of epithelial PD-L1 staining in esophageal and other gastrointestinal adenocarcinomas.Li, J. ; Dawidek, T. ; Liegsalz, V. ; Tzalis, V. ; Feuchtinger, A. ; Avril, S.
Intratumoral heterogeneity of common protein biomarkers assessed by immunohistochemistry in breast cancer tissues.Ly, A. ; Merl-Pham, J. ; Priller, M. ; Gruhn, F. ; Senninger, N. ; Ueffing, M. ; Hauck, S.M.
Proteomic profiling suggests central role of STAT signaling during retinal degeneration in the rd10 mouse model.Dislich, B. ; Stein, A. ; Seiler, C.A. ; Walch, A.K. ; Berezowska, S. ; Zlobec, I. ; Galvan, J.A. ; Langer, R.
Low frequency of epithelial PD-L1 staining in esophageal and other gastrointestinal adenocarcinomas.Li, J. ; Dawidek, T. ; Liegsalz, V. ; Tzalis, V. ; Feuchtinger, A. ; Avril, S.
Intratumoral heterogeneity of common protein biomarkers assessed by immunohistochemistry in breast cancer tissues.Gunnell, A. ; Webb, H.M. ; Wood, C.D. ; McClellan, M.J. ; Wichaidit, B. ; Kempkes, B. ; Jenner, R.G. ; Osborne, C. ; Farrell, P.J. ; West, M.J.
RUNX super-enhancer control through the Notch pathway by Epstein-Barr virus transcription factors regulates B cell growth.Grüner, B.M. ; Winkelmann, I. ; Feuchtinger, A. ; Sun, N. ; Balluff, B. ; Teichmann, N. ; Herner, A. ; Kalideris, E. ; Steiger, K. ; Braren, R. ; Aichler, M. ; Esposito, I. ; Schmid, R.M. ; Walch, A.K. ; Siveke, J.T.
Modeling therapy response and spatial tissue distribution of erlotinib in pancreatic cancer.Lahiri, S. ; Sun, N. ; Buck, A. ; Imhof, A. ; Walch, A.K.
MALDI imaging mass spectrometry as a novel tool for detecting histone modifications in clinical tissue samples.Hammoud, A.A. ; Kirstein, N. ; Mournetas, V. ; Darracq, A. ; Broc, S. ; Blanchard, C. ; Zeineddine, D. ; Mortada, M. ; Boeuf, H.
Murine embryonic stem cell plasticity is regulated through klf5 and maintained by metalloproteinase mmp1 and hypoxia.Kalchschmidt, J.S. ; Gillman, A.C. ; Paschos, K. ; Bazot, Q. ; Kempkes, B. ; Allday, M.J.
EBNA3C directs recruitment of RBPJ (CBF1) to chromatin during the process of gene repression in EBV infected B cells.Girst, S. ; Greubel, C. ; Reindl, J. ; Siebenwirth, C. ; Zlobinskaya, O. ; Walsh, D.W. ; Ilicic, K. ; Aichler, M. ; Walch, A.K. ; Wilkens, J.J. ; Multhoff, G. ; Dollinger, G. ; Schmid, T.E.
Proton minibeam radiation therapy reduces side effects in an in vivo mouse ear model.Sun, N. ; Fernandez, I.E. ; Wei, M. ; Wu, Y. ; Aichler, M. ; Eickelberg, O. ; Walch, A.K.
Pharmacokinetic and pharmacometabolomic study of pirfenidone in normal mouse tissues using high mass resolution MALDI-FTICR-mass spectrometry imaging.Dutta, S. ; Krause, A. ; Vosberg, S. ; Herold, T. ; Ksienzyk, B. ; Quintanilla-Martinez, L. ; Tizazu, B. ; Chopra, M. ; Graf, A. ; Krebs, S. ; Blum, H. ; Greif, P.A. ; Vetter, A. ; Metzeler, K.H. ; Rothenberg-Thurley, M. ; Schneider, M.R. ; Dahlhoff, M. ; Spiekermann, K. ; Zimber-Strobl, U. ; Wolf, E. ; Bohlander, S.K.
The target cell of transformation is distinct from the leukemia stem cell in murine CALM/AF10 leukemia models.Lahiri, S. ; Sun, N. ; Solis-Mezarino, V. ; Fedisch, A. ; Ninkovic, J. ; Feuchtinger, A. ; Götz, M. ; Walch, A.K. ; Imhof, A.
In situ detection of histone variants and modifications in mouse brain using imaging mass spectrometry.Krupka, C. ; Kufer, P. ; Kischel, R. ; Zugmaier, G. ; Lichtenegger, F.S. ; Köhnke, T. ; Vick, B. ; Jeremias, I. ; Metzeler, K.H. ; Altmann, T. ; Schneider, S. ; Fiegl, M. ; Spiekermann, K. ; Baeuerle, P.A. ; Hiddemann, W. ; Riethmüller, G. ; Subklewe, M.
Blockade of the PD-1/PD-L1 axis augments lysis of AML cells by the CD33/CD3-BiTE antibody construct AMG 330: Reversing a T-cell induced immune escape mechanism.van Nierop, G.P. ; Mautner, J. ; Mitterreiter, J.G. ; Hintzen, R.Q. ; Verjans, G.M.
Intrathecal CD8 T-cells of multiple sclerosis patients recognize lytic Epstein-Barr virus proteins.Zhang, S. ; Schneider, L.S. ; Vick, B. ; Grunert, M. ; Jeremias, I. ; Menche, D. ; Müller, R. ; Vollmar, A.M. ; Liebl, J.
Anti-leukemic effects of the V-ATPase inhibitor Archazolid A.Benito, J.M. ; Godfrey, L. ; Kojima, K. ; Hogdal, L. ; Wunderlich, M. ; Geng, H. ; Marzo, I. ; Harutyunyan, K.G. ; Golfman, L. ; North, P. ; Kerry, J. ; Ballabio, E. ; Ni Chonghaile, T. ; Gonzalo, O. ; Qiu, Y. ; Jeremias, I. ; Debose, L. ; O'Brien, E.T. ; Ma, H.C. ; Zhou, P. ; Jacamo, R. ; Park, E. ; Coombes, K.R. ; Zhang, N. ; Thomas, D.A. ; O'Brien, S.J. ; Kantarjian, H.M. ; Leverson, J.D. ; Kornblau, S.M. ; Andreeff, M. ; Mueschen, M. ; Zweidler-McKay, P.A. ; Mulloy, J.C. ; Letai, A.G. ; Milne, T.A. ; Konopleva, M.
MLL-rearranged acute lymphoblastic leukemias activate BCL-2 through H3K79 methylation and are sensitive to the BCL-2-specific antagonist ABT-199.Weth, V.
Untersuchungen zur Rolle der Rezeptortyrosinkinasen FLT3, DDR1 und DDR2 in der akuten myeloischen Leukämie.Ehrenberg, S.
Notch2 signalling in B cell activation, immune response and lymphomagenesis.Schäffner, M.
Chromatin remodeling in Epstein-Barr virus after induction of the lytic phase: Molecular characterization of the role of BZLF1 and its interactions.Aubele, M. ; Huber, M. ; Falkenberg, N. ; Gross, E. ; Braselmann, H. ; Walch, A.K. ; Schmitt, M.
uPA receptor and its interaction partners: Impact as potential therapeutic targets in triple-negative breast cancer.Fernandez, I.E. ; Na, S. ; Wei, M. ; Aichler, M. ; Walch, A.K. ; Eickelberg, O.
In-situ detection of pirfenidone and endogenous metabolites by maldi-imaging mass spectrometry in fibrotic tissue.Keller, I.E. ; Vosyka, O. ; Dann, A. ; Nathan, P. ; Takenaka, S. ; Overkleeft, H.S. ; Marcos, E. ; Adnot, S. ; Ruppert, C. ; Günther, A. ; Krauss-Etschmann, S. ; Adler, H. ; Eickelberg, O. ; Meiners, S.
Impaired immunoproteasome function in COPD.Reiter, K. ; Polzer, H. ; Krupka, C. ; Vick, B. ; Maiser, A. ; Subklewe, M. ; Jeremias, I. ; Leonhardt, H. ; Spiekermann, K. ; Greif, P.A.
Tyrosin kinase inhibition restores the membrane localization of FLT3-ITD.Garz, A.-K. ; Habringer, S. ; Wolf, S. ; Vick, B. ; Weickert, M.-T. ; Jeremias, I. ; Spiekermann, K. ; Peschel, C. ; Oostendorp, R.A.J. ; Keller, U. ; Goetze, K.S.
Azacitidine in combination with the selective FLT3 kinase inhibitor crenolanib effectively disrupts stromal protection of CD34+Leukemia-Initiating Cells (LIC) in FLT3-ITD+ Acute Myeloid Leukemia (AML).Ebinger, S. ; Erbey, O. ; Tiedt, S. ; Ziegenhain, C. ; Alves, C.C. ; Enard, W. ; Jeremias, I.
Single cell RNA sequencing reveals increased adhesion signals in treatment-resistant tumor stem cells in a preclinical mouse model of genetically engineered patient-derived acute lymphoblastic leukemia.Finkenzeller, C. ; Carlet, M. ; Vosberg, S. ; Greif, P.A. ; Jeremias, I.
Functional diversity of single stem cell clones in patients' acute lymphoblastic leukemia growing in mice: An adverse subclone with distinct DNA-methylation pattern, slow growth in vivo and drug resistance.Murakami, M.A. ; Christodoulou, A.N. ; Christie, A.L. ; DeSouza, T. ; Louissaint, A. ; Vojinovic, U. ; Koch, R. ; Li, L.S. ; Kallgren, S.P. ; Rao, P. ; Koester, J. ; Vadhi, R. ; Duberow, E. ; Morgan, E.A. ; Wang, H. ; Ahmed, S.S. ; Majewski, K.L. ; Konopleva, M. ; Tamburini, J. ; Gutierrez, A. ; Kelliher, M. ; Etchin, J. ; Jeremias, I. ; Weng, A.P. ; Kung, A.L. ; Lane, A.A. ; Carnache-Ottou, F. ; Izraeli, S. ; Jacobsen, E.S. ; Galinsky, I. ; Stone, R.M. ; Harris, M.H. ; Dorfman, D.M. ; Aster, J.C. ; Long, H. ; Silverman, L.B. ; Weinstock, D.M.
Proxe: A public repository of xenografts to facilitate studies of biology and expedite preclinical drug development in leukemia and lymphoma.Carlet, M. ; Vergalli, J. ; Finkenzeller, C. ; Grunert, M. ; Jeremias, I.
The novel technique of Genetically Engineered Patient-Derived Xenografts (GEPDX) reveals that the X-linked Inhibitor of Apoptosis Protein (XIAP) plays an essential role for maintenance and growth of patients' acute lymphoblastic leukemia in vivo.Carlet, M. ; Vergalli, J. ; Finkenzeller, C. ; Grunert, M. ; Jeremias, I.
Knockdown of XIAP sensitizes B-ALL cells towards chemotherapy in an innovative, dual luciferase in vivo competition assay.Vick, B. ; Rothenberg, M. ; Sandhöfer, N. ; Carlet, M. ; Finkenzeller, C. ; Krupka, C. ; Grunert, M. ; Trumpp, A. ; Corbacioglu, S. ; Ebinger, M. ; Andre, M.C. ; Hiddemann, W. ; Subklewe, M. ; Schneider, S. ; Metzeler, K.H. ; Spiekermann, K. ; Jeremias, I.
In vivo imaging facilitates reliable and sensitive monitoring of preclinical in vivo treatment trials in the individualized xenograft mouse model of AML.Carlet, M. ; Finkenzeller, C. ; Vergalli, J. ; Ebinger, S. ; Oezdemir, E. ; Heckl, B. ; Schneider, K. ; Terzyiska, N. ; Tiedt, S. ; Alves, C. ; Grunert, M. ; Vick, B. ; Jeremias, I.
Functional characterization ofacute leukemias.Finkenzeller, C. ; Carlet, M. ; Jeremias, I.
Single cell clones from a patient with all show different drug sensitivity and growth behavior in vivo.Ebinger, S. ; Mura, L. ; Grunert, M. ; Jeremias, I.
Drug sensitivity of patient-derived ALL tumor cells is impaired by co-culture with feeder cells mimicking the in vivo micro-environment.Raffegerst, S.H. ; Steer, B. ; Hohloch, M. ; Adler, H.
Prevention of tumor formation by latent gammaherpesvirus infection.Krupka, C. ; Kufer, P. ; Kischel, R. ; Zugmaier, G. ; Köhnke, T. ; Lichtenegger, F.S. ; Altmann, T. ; Spiekermann, K. ; Vick, B. ; Jeremias, I. ; Hiddemann, W. ; Subklewe, M.
Combining immune checkpoint inhibition with the CD33 BiTE (R) antibody construct AMG 330 to enhance T cell mediated lysis of primary AML cells.Habringer, S. ; Li, Z. ; Pietschmann, E. ; Slawska, J. ; Walch, A.K. ; Peschel, C. ; Keller, U.
Very early functional in-vivo imaging to predict response to B cell receptor pathway targeting in lymphoma.Garz, A.-K. ; Weickert, M.-T. ; Pagel, C. ; Habringer, S. ; Vick, B. ; Jeremias, I. ; Keller, U. ; Oostendorp, R. ; Peschel, C. ; Goetze, K.
The combination of crenolanib and azacitidine effectively targets leukemia-initiating cells in FLT3-ITD+ AML to overcome protection by the bone marrow niche.Ameres, S. ; Liang, X. ; Wiesner, M. ; Mautner, J. ; Moosmann, A.
A diverse repertoire of CD4 T cells targets the immediate-early 1 protein of human cytomegalovirus.Kempkes, B. ; Robertson, E.S.
Epstein-Barr virus latency: Current and future perspectives.Tiedt, S. ; Ebinger, S. ; Alves, C.C. ; Oezdemir, E. ; Gires, O. ; Jeremias, I.
A rare subpopulation of quiescent, drug resistant stem cells in patients' all cells growing in mice.Finkenzeller, C. ; Carlet, M. ; Vosberg, S. ; Wolf, S. ; Greif, P.A. ; Jeremias, I.
Patient's single stem cell clones of acute lymphoblastic leukemia show drug resistance and slow proliferation in mice in vivo.Carlet, M. ; Vergalli, J. ; Finkenzeller, C. ; Grunert, M. ; Jeremias, I.
XIAP exhibits an essential role for patients' all cells growing in vivo as shown by a novel technique for stable knockdown in Patient-Derived Xenograft (PDX) all cells.Hammerschmidt, W.
The epigenetic life cycle of epstein–barr virus.Ghasemi, A. ; Jeddi-Tehrani, M. ; Mautner, J. ; Salari, M.H. ; Zarnani, A.H.
Simultaneous immunization of mice with Omp31 and TF provides protection against Brucella melitensis infection.Kieser, A. ; Sterz, K.
The Latent Membrane Protein 1 (LMP1).Kempkes, B. ; Ling, P.D.
EBNA2 and its coactivator EBNA-LP.Chekkoury, A. ; Gateau, J. ; Driessen, W.H.P. ; Symvoulidis, P. ; Bézière, N. ; Feuchtinger, A. ; Walch, A.K. ; Ntziachristos, V.
Optical mesoscopy without the scatter: Broadband multispectral optoacoustic mesoscopy.Pfluger, P.T. ; Kabra, D.G. ; Aichler, M. ; Schriever, S.C. ; Pfuhlmann, K. ; Casquero García, V. ; Lehti, M. ; Weber, J. ; Kutschke, M. ; Rozman, J. ; Elrod, J.W. ; Hevener, A.L. ; Feuchtinger, A. ; Hrabě de Angelis, M. ; Walch, A.K. ; Rollmann, S.M. ; Aronow, B.J. ; Müller, T.D. ; Perez-Tilve, D. ; Jastroch, M. ; de Luca, M. ; Molkentin, J.D. ; Tschöp, M.H.
Calcineurin links mitochondrial elongation with energy metabolism.Sweetwyne, M.T. ; Gruenwald, A. ; Niranjan, T. ; Nishinakamura, R. ; Strobl, L.J. ; Susztak, K.
Notch1 and Notch2 in podocytes play differential roles during diabetic nephropathy development.Semren, N. ; Welk, V. ; Korfei, M. ; Keller, I.E. ; Fernandez, I.E. ; Adler, H. ; Günther, A. ; Eickelberg, O. ; Meiners, S.
Regulation of 26S proteasome activity in pulmonary fibrosis.Kiermayer, C. ; Northrup, E. ; Schrewe, A. ; Walch, A.K. ; Hrabě de Angelis, M. ; Schoensiegel, F. ; Zischka, H. ; Prehn, C. ; Adamski, J. ; Bekeredjian, R. ; Ivandic, B. ; Kupatt, C. ; Brielmeier, M.
Heart-specific knockout of the mitochondrial Thioredoxin reductase (Txnrd2) induces metabolic and contractile dysfunction in the aging myocardium.Alsadeq, A. ; Strube, S. ; Krause, S. ; Carlet, M. ; Jeremias, I. ; Vokuhl, C. ; Loges, S. ; Aguirre-Ghiso, J.A. ; Trauzold, A. ; Cario, G. ; Stanulla, M. ; Schrappe, M. ; Schewe, D.M.
Effects of p38α/β inhibition on Acute Lymphoblastic Leukemia (ALL) proliferation and survival in vivo.Rancan, C. ; Schirrmann, L. ; Hüls, C. ; Zeidler, R. ; Moosmann, A.
Latent membrane protein LMP2A impairs recognition of EBV-infected cells by CD8+ T cells.Friberg, A. ; Thumann, S. ; Hennig, J. ; Zou, P. ; Nößner, E. ; Ling, P.D. ; Sattler, M. ; Kempkes, B.
The EBNA-2 N-terminal transactivation domain folds into a dimeric structure required for target gene activation.Groß, C. ; Steiger, K. ; Sayyed, S. ; Heid, I. ; Feuchtinger, A. ; Walch, A.K. ; Hess J. ; Unger, K. ; Zitzelsberger, H. ; Settles, M. ; Schlitter, A.M. ; Dworniczak, J. ; Altomonte, J. ; Ebert, O. ; Schwaiger, M. ; Rummeny, E.J. ; Steingötter, A. ; Esposito, I. ; Braren, R.
Model matters: Differences in orthotopic rat hepatocellular carcinoma physiology determine therapy response to sorafenib.Keller, I.E. ; Vosyka, O. ; Takenaka, S. ; Kloß, A. ; Dahlmann, B. ; Willems, L.I. ; Verdoes, M. ; Overkleeft, H.S. ; Marcos, E. ; Adnot, S. ; Hauck, S.M. ; Ruppert, C. ; Günther, A. ; Herold, S. ; Ohno, S. ; Adler, H. ; Eickelberg, O. ; Meiners, S.
Regulation of immunoproteasome function in the lung.Velikova, V.B. ; Müller, C. ; Ghirardo, A. ; Rock, T. ; Aichler, M. ; Walch, A.K. ; Schmitt-Kopplin, P. ; Schnitzler, J.-P.
Knocking down of isoprene emission modifies the lipid matrix of thylakoid membranes and influences the chloroplast ultrastructure in poplar.Buck, A. ; Ly, A. ; Balluff, B. ; Sun, N. ; Gorzolka, K. ; Feuchtinger, A. ; Janssen, K.P. ; Kuppen, P.J. ; van de Velde, C.J. ; Weirich, G. ; Erlmeier, F. ; Langer, R. ; Aubele, M. ; Zitzelsberger, H. ; Aichler, M. ; Walch, A.K.
High-resolution MALDI-FT-ICR MS imaging for the analysis of metabolites from formalin-fixed paraffin-embedded clinical tissue samples.Bauer, L. ; Takacs, A. ; Slotta-Huspenina, J. ; Langer, R. ; Becker, K. ; Novotny, A. ; Ott, K. ; Walch, A.K. ; Hapfelmeier, A. ; Keller, G.
Clinical significance of NOTCH1 and NOTCH2 expression in gastric carcinomas: An immunohistochemical study.Amort, M. ; Nachbauer, B. ; Tuzlak, S. ; Kieser, A. ; Schepers, A. ; Villunger, A. ; Polacek, N.
Expression of the vault RNA protects cells from undergoing apoptosis.Steinbrück, L. ; Gustems, M. ; Medele, S. ; Schulz, T.F. ; Lutter, D. ; Hammerschmidt, W.
K1 and K15 of Kaposi sarcoma-associated herpes virus are partial functional homologues of latent membrane protein 2A of Epstein-Barr virus.Erlmeier, F. ; Feuchtinger, A. ; Borgmann, D.M. ; Rudelius, M. ; Autenrieth, M. ; Walch, A.K. ; Weirich, G.
Supremacy of modern morphometry in typing renal oncocytoma and malignant look-alikes.Ingold, I. ; Aichler, M. ; Yefremova, E. ; Roveri, A. ; Buday, K. ; Doll, S. ; Tasdemir, A. ; Hoffard, N. ; Wurst, W. ; Walch, A.K. ; Ursini, F. ; Friedmann Angeli, J.P.F. ; Conrad, M.
Expression of a catalytically inactive mutant form of Glutathione peroxidase 4 (Gpx4) confers a dominant-negative effect in male fertility.Oetjen, J. ; Veselkov, K. ; Watrous, J. ; McKenzie, J.S. ; Becker, M. ; Hauberg-Lotte, L. ; Kobarg, J.H. ; Strittmatter, N. ; Mróz, A.K. ; Hoffmann, F. ; Trede, D. ; Palmer, A. ; Schiffler, S. ; Steinhorst, K. ; Aichler, M. ; Goldin, R. ; Guntinas-Lichius, O. ; von Eggeling, F. ; Thiele, H. ; Maedler, K. ; Walch, A.K. ; Maass, P. ; Dorrestein, P.C. ; Takats, Z. ; Alexandrov, T.
Benchmark datasets for 3D MALDI- and DESI-imaging mass spectrometry.Almstätter, I. ; Mykhaylyk, O. ; Settles, M. ; Altomonte, J. ; Aichler, M. ; Walch, A.K. ; Rummeny, E.J. ; Ebert, O. ; Plank, C. ; Braren, R.
Characterization of magnetic viral complexes for targeted delivery in oncology.Uda, N.R. ; Seibert, V. ; Stenner-Liewen, F. ; Müller, P. ; Herzig, P. ; Gondi, G. ; Zeidler, R. ; van Dijk, M. ; Zippelius, A. ; Renner, C.
Esterase activity of carbonic anhydrases serves as surrogate for selecting antibodies blocking hydratase activity.Genitsch, V. ; Novotny, A. ; Seiler, C.A. ; Kröll, D. ; Walch, A.K. ; Langer, R.
Epstein-Barr virus in gastro-esophageal adenocarcinomas - single center experiences in the context of current literature.Bruns, H. ; Büttner, M. ; Fabri, M. ; Mougiakakos, D. ; Bittenbring, J.T. ; Hoffmann, M.H. ; Beier, F. ; Pasemann, S. ; Jitschin, R. ; Hofmann, A.D. ; Neumann, F.J. ; Daniel, C. ; Maurberger, A. ; Kempkes, B. ; Amann, K. ; Mackensen, A. ; Gerbitz, A.
Vitamin D-dependent induction of cathelicidin in human macrophages results in cytotoxicity against high-grade B cell lymphoma.Aichler, M. ; Walch, A.K.
MALDI Imaging mass spectrometry: Current frontiers and perspectives in pathology research and practice.Schmitt, S. ; Eberhagen, C. ; Weber, S. ; Aichler, M. ; Zischka, H.
Isolation of mitochondria from cultured cells and liver tissue biopsies for molecular and biochemical analyses.Schulz, S. ; Lichtmannegger, J. ; Schmitt, S. ; Leitzinger, C. ; Eberhagen, C. ; Einer, C. ; Kerth, J. ; Aichler, M. ; Zischka, H.
A protocol for the parallel isolation of intact mitochondria from rat liver, kidney, heart, and brain.Vick, B. ; Rothenberg, M. ; Sandhöfer, N. ; Carlet, M. ; Finkenzeller, C. ; Krupka, C. ; Grunert, M. ; Trumpp, A. ; Corbacioglu, S. ; Ebinger, M. ; Andre, M.C. ; Hiddemann, W. ; Schneider, S. ; Subklewe, M. ; Metzeler, K.H. ; Spiekermann, K. ; Jeremias, I.
An advanced preclinical mouse model for acute myeloid leukemia using patients' cells of various genetic subgroups and in vivo bioluminescence imaging.Yu, X. ; Ilecka, M. ; Bartlett, E.J. ; Schneidt, V. ; Bhat, R. ; Mautner, J. ; Feederle, R. ; Delecluse, H.J.
Antigen-armed antibodies targeting B lymphoma cells effectively activate antigen-specific CD4+ T cells.Zarzycka, B. ; Seijkens, T. ; Nabuurs, S.B. ; Ritschel, T. ; Grommes, J. ; Soehnlein, O. ; Schrijver, R.S. ; van Tiel, C.M. ; Hackeng, T.M. ; Weber, C. ; Giehler, F. ; Kieser, A. ; Lutgens, E. ; Vriend, G. ; Nicolaes, G.A.F.
Discovery of small molecule CD40-TRAF6 inhibitors.Aichler, M. ; Huber, K. ; Schilling, F. ; Lohöfer, F. ; Kosanke, K. ; Meier, R. ; Rummeny, E.J. ; Walch, A.K. ; Wildgruber, M.
Spatially resolved quantification of Gadolinium(III)-based magnetic resonance agents in tissue by MALDI imaging mass spectrometry after in vivo MRI.God, J.M. ; Cameron, C. ; Figueroa, J. ; Amria, S. ; Hossain, A. ; Kempkes, B. ; Bornkamm, G.W. ; Stuart, R.K. ; Blum, J.S. ; Haque, A.
Elevation of c-MYC disrupts HLA class II-mediated immune recognition of human B cell tumors.Bi, Z. ; Merl-Pham, J. ; Uehlein, N. ; Zimmer, I. ; Mühlhans, S. ; Aichler, M. ; Walch, A.K. ; Kaldenhoff, R. ; Palme, K. ; Schnitzler, J.-P. ; Block, K.
RNAi-mediated downregulation of poplar Plasma membrane Intrinsic Proteins (PIPs) changes plasma membrane proteome composition and affects leaf physiology.Lemmermann, N.A.W. ; Krmpotic, A. ; Podlech, J. ; Brizic, I. ; Prager, A. ; Adler, H. ; Karbach, A. ; Wu, Y. ; Jonjic, S. ; Reddehase, M.J. ; Adler, B.
Non-redundant and redundant roles of cytomegalovirus gH/gL complexes in host organ entry and intra-tissue spread.Sun, C. ; Schattgen, S.A. ; Pisitkun, P. ; Jorgensen, J.P. ; Hilterbrand, A.T. ; Wang, L.J. ; West, J.A. ; Hansen, K. ; Horan, K.A. ; Jakobsen, M.R. ; O'Hare, P. ; Adler, H. ; Sun, R. ; Ploegh, H.L. ; Damania, B. ; Upton, J.W. ; Fitzgerald, K.A. ; Paludan, S.R.
Evasion of innate cytosolic DNA sensing by a gammaherpesvirus facilitates establishment of latent infection.Teiluf, K. ; Seidl, C. ; Blechert, B. ; Gaertner, F.C. ; Gilbertz, K.P. ; Fernandez, V. ; Bassermann, F. ; Endell, J. ; Boxhammer, R. ; Leclair, S. ; Vallon, M. ; Aichler, M. ; Feuchtinger, A. ; Bruchertseifer, F. ; Morgenstern, A. ; Essler, M.
α-Radioimmunotherapy with 213Bi-anti-CD38 immunoconjugates is effective in a mouse model of human multiple myeloma.Helmbrecht, M.S. ; Soellner, H. ; Truckenbrodt, A.M. ; Sundermeier, J. ; Cohrs, C.M. ; Hans, W. ; Hrabě de Angelis, M. ; Feuchtinger, A. ; Aichler, M. ; Fouad, K. ; Huber, A.B.
Loss of Npn1 from motor neurons causes postnatal deficits independent from Sema3A signaling.Diakopoulos, K.N. ; Lesina, M. ; Wörmann, S. ; Song, L. ; Aichler, M. ; Schild, L. ; Artati, A. ; Römisch-Margl, W. ; Wartmann, T. ; Fischer, R. ; Kabiri, Y. ; Zischka, H. ; Halangk, W. ; Demir, I.E. ; Pilsak, C. ; Walch, A.K. ; Mantzoros, C.S. ; Steiner, J.M. ; Erkan, M. ; Schmid, R.M. ; Witt, H. ; Adamski, J. ; Algül, H.
Impaired autophagy induces chronic atrophic pancreatitis in mice via sex- and nutrition-dependent processes.Ly, A. ; Schöne, C. ; Becker, M. ; Rattke, J. ; Meding, S. ; Aichler, M. ; Suckau, D. ; Walch, A.K. ; Hauck, S.M. ; Ueffing, M.
High-resolution MALDI mass spectrometric imaging of lipids in the mammalian retina.Kulic, I. ; Robertson, G. ; Chang, L. ; Baker, J.H. ; Lockwood, W.W. ; Mok, W. ; Fuller, M. ; Fournier, M. ; Wong, N. ; Chou, V. ; Robinson, M.D. ; Chun, H.J. ; Gilks, B. ; Kempkes, B. ; Thomson, T.A. ; Hirst, M. ; Minchinton, A.I. ; Lam, W.L. ; Jones, S. ; Marra, M. ; Karsan, A.
Loss of the Notch effector RBPJ promotes tumorigenesis.McDonnell, L.A. ; Römpp, A. ; Balluff, B.D. ; Heeren, R.M.A. ; Albar, J.P. ; Andrén, P.E. ; Corthals, G.L. ; Walch, A.K. ; Stoeckli, M.
Discussion point: Reporting guidelines for mass spectrometry imaging.Ermolayev, V. ; Mohajerani, P. ; Ale, A.B.F ; Sarantopoulos, A. ; Aichler, M. ; Kayser, G. ; Walch, A.K. ; Ntziachristos, V.
Early recognition of lung cancer by integrin targeted imaging in K-ras mouse model.Berchtold, S. ; Grünwald, B. ; Krüger, A. ; Reithmeier, A. ; Hähl, T. ; Cheng, T. ; Feuchtinger, A. ; Born, D. ; Erkan, M. ; Kleeff, J. ; Esposito, I.
Collagen type V promotes the malignant phenotype of pancreatic ductal adenocarcinoma.Kahle-Stephan, M. ; Schäfer, A. ; Seelig, A. ; Schultheiß, J. ; Wu, M. ; Aichler, M. ; Leonhardt, J. ; Rathkolb, B. ; Rozman, J. ; Sarioglu, H. ; Hauck, S.M. ; Ueffing, M. ; Wolf, E. ; Kastenmüller, G. ; Adamski, J. ; Walch, A.K. ; Hrabě de Angelis, M. ; Neschen, S.
High fat diet-induced modifications in membrane lipid and mitochondrial-membrane protein signatures precede the development of hepatic insulin resistance in mice.Kim, D.K. ; Lee, J. ; Kim, S.R. ; Choi, D.S. ; Yoon, Y.J. ; Kim, J.H. ; Go, G. ; Nhung, D. ; Hong, K. ; Jang, S.C. ; Kim, S.H. ; Park, K.S. ; Kim, O.Y. ; Park, H.T. ; Seo, J.H. ; Aikawa, E. ; Baj-Krzyworzeka, M. ; van Balkom, B.W. ; Belting, M. ; Blanc, L. ; Bond, V. ; Bongiovanni, A. ; Borràs, F.E. ; Buée, L. ; Buzás, E.I. ; Cheng, L. ; Clayton, A. ; Cocucci, E. ; Dela Cruz, C.S. ; Desiderio, D.M. ; di Vizio, D. ; Ekström, K. ; Falcón-Pérez, J.M. ; Gardiner, C. ; Giebel, B. ; Greening, D.W. ; Gross, J.C. ; Gupta, D. ; Hendrix, A. ; Hill, A.F. ; Hill, M.M. ; Nolte-'t Hoen, E. ; Hwang, D.W. ; Inal, J. ; Jagannadham, M.V. ; Jayachandran, M. ; Jee, Y.K. ; Jørgensen, M. ; Kim, K.P. ; Kim, Y.K. ; Kislinger, T. ; Lässer, C. ; Lee, D.S. ; Lee, H. ; van Leeuwen, J. ; Lener, T. ; Liu, M.L. ; Lötvall, J. ; Marcilla, A. ; Mathivanan, S. ; Möller, A. ; Morhayim, J. ; Mullier, F. ; Nazarenko, I. ; Nieuwland, R. ; Nunes, D.N. ; Pang, K. ; Park, J. ; Patel, T. ; Pocsfalvi, G. ; del Portillo, H. ; Putz, U. ; Ramirez, M.I. ; Rodrigues, M.L. ; Roh, T.Y. ; Royo, F. ; Sahoo, S. ; Schiffelers, R. ; Sharma, S. ; Siljander, P. ; Simpson, R.J. ; Soekmadji, C. ; Stahl, P. ; Stensballe, A. ; Stępień, E. ; Tahara, H. ; Trummer, A. ; Valadi, H. ; Vella, L.J. ; Wai, S.N. ; Witwer, K. ; Yáñez-Mó, M. ; Youn, H. ; Zeidler, R. ; Gho, Y.S.
EVpedia: A community web portal for extracellular vesicles research.Sandhöfer, N. ; Metzeler, K.H. ; Carlet, M. ; Dufour, A. ; Fröhling, S. ; Groiß, V. ; Grunert, M. ; Herold, T. ; Hinrichsen, T. ; Hiddemann, W. ; Klein, H.G. ; Rothenburg, M. ; Schneider, S. ; Subklewe, M. ; Tiedt, S. ; Wachter, O. ; Walter, G. ; Jeremias, I. ; Spiekermann, K.
Dual PI3K/mTOR inhibition shows antileukemic activity in MLL rearranged acute myeloid leukemia.Buck, A. ; Halbritter, S. ; Späth, C. ; Feuchtinger, A. ; Aichler, M. ; Zitzelsberger, H. ; Janssen, K.P. ; Walch, A.K.
Distribution and quantification of irinotecan and its active metabolite SN-38 in colon cancer murine model systems using MALDI MSI.Schenck, T.L. ; Stewart, J. ; Lin, S. ; Aichler, M. ; Machens, H.G. ; Giunta, R.E.
Anatomical and histomorphometric observations on the transfer of the anterior interosseous nerve to the deep branch of the ulnar nerve.Selmansberger, M. ; Feuchtinger, A. ; Zurnadzhy, L. ; Michna, A. ; Kaiser, J.C. ; Abend, M. ; Brenner, A. ; Bogdanova, T. ; Walch, A.K. ; Unger, K. ; Zitzelsberger, H. ; Hess J.
CLIP2 as radiation biomarker in papillary thyroid carcinoma.Baumgart, A. ; Mazur, P.K. ; Anton, M. ; Rudelius, M. ; Schwamborn, K. ; Feuchtinger, A. ; Behnke, K. ; Walch, A.K. ; Braren, R. ; Peschel, C. ; Duyster, J. ; Siveke, J.T. ; Dechow, T.
Opposing role of Notch1 and Notch2 in a KrasG12D-driven murine non-small cell lung cancer model.Kandemir, M. ; Feuchtinger, A. ; Walch, A.K. ; Hamprecht, F.A.
Digital pathology: Multiple instance learning can detect Barrett's cancer.Huber, M. ; Falkenberg, N. ; Schmitt, M. ; Braselmann, H. ; Mall, R. ; Jakovac, M. ; Walch, A.K. ; Höfler, H. ; Aubele, M.
uPAR and its interaction partners: potential new therapy targets in triple negative breast cancer.Selmansberger, M. ; Feuchtinger, A. ; Zurnadzhy, L. ; Höfig, I. ; Bogdanova, T. ; Walch, A.K. ; Unger, K. ; Zitzelsberger, H. ; Hess J.
CLIP2 as radiation biomarker in papillary thyroid carcinoma.Bruns, H. ; Buettner, M. ; Fabri, M. ; Mougiakakos, D. ; Bittenbring, J.T. ; Pasemann, S. ; Neumann, F.J. ; Maurberger, A. ; Kempkes, B. ; Mackensen, A. ; Gerbitz, A.
Vitamin D-dependent induction of cathelicidin in human macrophages results in cytotoxicity against high grade B-cell lymphoma.Dutta, S. ; Krause, A. ; Vosberg, S. ; Herold, T. ; Ksienzyk, B. ; Quintanilla-Fend, L. ; Tizazu, B. ; Graf, A. ; Krebs, S. ; Blum, H. ; Greif, P.A. ; Schneider, M. ; Dahlhof, M. ; Spiekermann, K. ; Zimber-Strobl, U. ; Wolf, E. ; Bohlander, S.K.
Analysis of the tissue-specific expression requirements and identification of cooperating mutations for leukemogenesis in an inducible CALM/AF10 knock-in mouse model.Jost, P.J. ; Yabal, M. ; Adler, H. ; Knies, N. ; Gross, C. ; Damgaard, R.B. ; Kanegane, H. ; Peschel, C. ; Strasser, A. ; Gross, O. ; Ruland, J. ; Gyrd-Hansen, M.
A mouse model for XLP-2 disease uncovers a critical function for IL-1beta and TNF in driving hyper-inflammation.Jeremias, I. ; Vick, B. ; Rothenberg, M. ; Sandhöfer, N. ; Carlet, M. ; Krupka, C. ; Trumpp, A. ; Corbacioglu, S. ; Ebinger, M. ; Andre, M.C. ; Hiddemann, W. ; Schneider, S. ; Subklewe, M. ; Metzeler, K.H. ; Spiekermann, K.
Bioluminescence in vivo imaging improves the model of individual patients' AML cells growing in mice for sensitive and reliable preclinical treatment trials on various genetic subgroups.Tiedt, S.
Eine seltene und sich langsam teilende Fraktion von Zellen der akuten lymphatischen Leukämie im Knochenmark von NSG-Mäusen ist chemoresistent.Böttinger, N.
Adoptive immunotherapy for treatment of chronic hepatitis B.Becker, L. ; Kling, E. ; Schiller, E. ; Zeh, R. ; Schrewe, A. ; Hölter, S.M. ; Mossbrugger, I. ; Calzada-Wack, J. ; Strecker, V. ; Wittig, I. ; Dumitru, I. ; Wenz, T. ; Bender, A. ; Aichler, M. ; Janik, D. ; Neff, F. ; Walch, A.K. ; Quintanilla-Fend, L. ; Floß, T. ; Bekeredjian, R. ; Gailus-Durner, V. ; Fuchs, H. ; Wurst, W. ; Meitinger, T. ; Prokisch, H. ; Hrabě de Angelis, M. ; Klopstock, T.
MTO1-deficient mouse model mirrors the human phenotype showing complex I defect and cardiomyopathy.Davari, K. ; Frankenberger, S. ; Schmidt, A. ; Tomi, N.S. ; Jungnickel, B.
Checkpoint kinase 2 is required for efficient immunoglobulin diversification.Ravasz, M.
The role of ORC6 in the human cell.Wachter, F.
Der konträre Einfluss von p53 auf die extrinsische und intrinsische Apoptoseinduktion in Tumorzellen.Sterz, K.
A systematical analysis of the signal transduction pathways induced by the Latent Membrane Protein 1 (LMP1) of Epstein-Barr virus.Maier, S.K.
Towards comprehensive identification of proteins from MALDI imaging.Mannes, A.M.
Dissecting the role of selenothiol- versus thiol-based catalysis using the model enzyme glutathione peroxidase 4 (GPx4).Bruns, H. ; Bittenbring, J.T. ; Mougiakakos, D. ; Fabri, M. ; Buettner, M. ; Pasemann, S. ; Kempkes, B. ; Mackensen, A. ; Gerbitz, A.
Vitamin D-dependent induction of cathelicidin in human macrophages results in cytotoxicity against high grade B-cell lymphoma.Yabal, M. ; Müller, N. ; Adler, H. ; Knies, N. ; Gross, C.J. ; Damgaard, R.B. ; Kanegane, H. ; Ringelhan, M. ; Kaufmann, T. ; Heikenwälder, M. ; Strasser, A. ; Gross, O. ; Ruland, J. ; Peschel, C. ; Gyrd-Hansen, M. ; Jost, P.J.
Aberrant TNF signalling in dendritic cells in the absence of XIAP contributes to X-linked lymphoproliferative disease (XLP-2) by exaggerated necroptosis.Baumann, U. ; Fernández-Sáiz, V. ; Rudelius, M. ; Lemeer, S. ; Rad, R. ; Knorn, A.M. ; Slawska, J. ; Engel, K. ; Jeremias, I. ; Li, Z. ; Tomiatti, V. ; Illert, A.L. ; Targosz, B.S. ; Braun, M. ; Perner, S. ; Leitges, M. ; Klapper, W. ; Dreyling, M. ; Miething, C. ; Lenz, G. ; Rosenwald, A. ; Peschel, C. ; Keller, U. ; Kuster, B. ; Bassermann, F.
Disruption of the PRKCD-FBXO25-HAX-1 axis attenuates the apoptotic response and drives lymphomagenesis.Friedmann Angeli, J.P.F. ; Schneider, M. ; Proneth, B. ; Tyurina, Y.Y. ; Tyurin, V.A. ; Hammond, V.J. ; Herbach, N. ; Aichler, M. ; Walch, A.K. ; Eggenhofer, E. ; Basavarajappa, D. ; Rådmark, O. ; Kobayashi, S. ; Seibt, T. ; Beck, H. ; Neff, F. ; Esposito, I. ; Wanke, R. ; Förster, H. ; Yefremova, O. ; Heinrichmeyer, M. ; Bornkamm, G.W. ; Geissler, E.K. ; Thomas, S.B. ; Stockwell, B.R. ; O'Donnell, V.B. ; Kagan, V.E. ; Schick, J. ; Conrad, M.
Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice.Finkenzeller, C. ; Carlet, M. ; Jeremias, I.
Optimization of lentiviral transduction in patien-derived acute leukemia cells growing mice.Vick, B. ; Rothenberg, M. ; Sandhöfer, N. ; Carlet, M. ; Finkenzeller, C. ; Krupka, C. ; Grunert, M. ; Trumpp, A. ; Corbacioglu, S. ; Ebinger, M. ; Andre, M.C. ; Hiddemann, W. ; Subklewe, M. ; Schneider, S. ; Spiekermann, K. ; Metzeler, K.H. ; Jeremias, I.
Serial transplantation and in vivo monitoring of patient-derived xenografts: An advanced preclinical model to study diverse genetic AML subgroups in mice.Neudoerfl, C. ; Daemen, K. ; Stevanovic-Meyer, M. ; Keil, J.E. ; Hoffmann, U. ; Lehner, F. ; Haller, H. ; Blume, C. ; Hammerschmidt, W. ; Zeidler, R. ; Falk, C.S.
Costimulation blockade by belatacept inhibits allo-specific de novo T cell responses and preserves virus-specific memory T cell responses in healthy donors and kidney transplanted patients.Aichler, M. ; Luber, B. ; Lordick, F. ; Walch, A.K.
Proteomic and metabolic prediction of response to therapy in gastric cancer.Tomi, N.S. ; Davari, K. ; Grotzky, D. ; Loos, F. ; Böttcher, K. ; Frankenberger, S. ; Jungnickel, B.
Analysis of SHPRH functions in DNA repair and immunoglobulin diversification.Huber, K. ; Feuchtinger, A. ; Borgmann, D.M. ; Li, Z. ; Aichler, M. ; Hauck, S.M. ; Zitzelsberger, H. ; Schwaiger, M. ; Keller, U. ; Walch, A.K.
A novel approach of MALDI drug imaging, immunohistochemistry, and digital image analysis for drug distribution studies in tissues.Gegg, M. ; Böttcher, A. ; Burtscher, I. ; Hasenöder, S. ; van Campenhout, C.A. ; Aichler, M. ; Walch, A.K. ; Grant, S.G. ; Lickert, H.
Flattop regulates basal body docking and positioning in mono- and multiciliated cells.Gabaev, I. ; Elbasani, E. ; Ameres, S. ; Steinbrück, L. ; Stanton, R. ; Döring, M. ; Lenac Rovis, T. ; Kalinke, U. ; Jonjic, S. ; Moosmann, A. ; Messerle, M.
Expression of the human cytomegalovirus UL11 glycoprotein in viral infection and evaluation of its effect on virus-epecific CD8 T cells.Balluff, B. ; Frese, C.K. ; Maier, S.K. ; Schöne, C. ; Kuster, B. ; Schmitt, M. ; Aubele, M. ; Höfler, H. ; Deelder, A.M. ; Heck, A.J. ; Hogendoorn, P.C.W. ; Morreau, J. ; Altelaar, A.F. ; Walch, A.K. ; McDonnell, L.A.
De novo discovery of phenotypic intra-tumor heterogeneity using imaging mass spectrometry.Aichler, M. ; Motschmann, M. ; Jütting, U. ; Luber, B. ; Becker, K. ; Ott, K. ; Lordick, F. ; Langer, R. ; Feith, M. ; Siewert, J.R. ; Walch, A.K.
Epidermal Growth Factor Receptor (EGFR) is an independent adverse prognostic factor in esophageal adenocarcinoma patients treated with cisplatin-based neoadjuvant chemotherapy.Lehnert, C. ; Weiswange, M. ; Jeremias, I. ; Bayer, C. ; Grunert, M. ; Debatin, K.M. ; Strauss, G.P.
TRAIL-receptor costimulation inhibits proximal TCR signaling and suppresses human T cell activation and proliferation.Feuchtinger, A. ; Stiehler, T. ; Jütting, U. ; Marjanovic, G. ; Luber, B. ; Langer, R. ; Walch, A.K.
Image analysis of immunohistochemistry is superior to visual scoring as shown for patient outcome of esophageal adenocarcinoma.Maier, S.K. ; Bashkueva, K. ; Rösli, C. ; Skerra, A. ; Kuster, B.
PAS-cal: A repetitive peptide sequence calibration standard for MALDI mass spectrometry.Mohr, C.F. ; Kalmer, M.A. ; Gross, C. ; Mann, M.C. ; Sterz, K. ; Kieser, A. ; Fleckenstein, B.W. ; Kress, A.K.
The tumor marker Fascin is induced by the Epstein-Barr virus-encoded oncoprotein LMP1 via NF-κB in lymphocytes and contributes to their invasive migration.Alves, C.C. ; Tiedt, S. ; Jeremias, I.
Identification and isolation of a rare population of low-cycling, self-renewing and drug-resistant acute lymphoblastic leukemia xenograft cells.Bazot, Q. ; Deschamps, T. ; Tafforeau, L. ; Siouda, M. ; Leblanc, P. ; Harth-Hertle, M.L. ; Rabourdin-Combe, C. ; Lotteau, V. ; Kempkes, B. ; Tommasino, M. ; Gruffat, H. ; Manet, E.
Epstein-Barr virus nuclear antigen 3A protein regulates CDKN2B transcription via interaction with MIZ-1.Falk, C.S. ; Daemen, K. ; Stevanovic-Meyer, M. ; Lehner, F. ; Haller, H. ; Blume, C. ; Hammerschmidt, W. ; Zeidler, R. ; Neudoerfl, C.
Belatacept can inhibit allo-specific T cell responses in a donor-dependent manner but preserves virus-specific memory T cell-responses.Slotta-Huspenina, J. ; Becker, K.F. ; Feith, M. ; Walch, A.K. ; Langer, R.
Heat Shock Protein 90 (HSP90) and Her2 in adenocarcinomas of the esophagus.Adler, H. ; Steer, B. ; Juskewitz, E. ; Kammerer, R.
To the editor: Murine gammaherpesvirus 68 (MHV-68) escapes from NK-cell-mediated immune surveillance by a CEACAM1-mediated immune evasion mechanism.Schmitt, S. ; Schulz, S. ; Schropp, E.-M. ; Eberhagen, C. ; Simmons, A. ; Beisker, W. ; Aichler, M. ; Zischka, H.
Why to compare absolute numbers of mitochondria.Buck, A. ; Walch, A.K.
In situ drug and metabolite analyzes in biological and clinical research by MALDI MS imaging.Hojer, C. ; Frankenberger, S. ; Strobl, L.J. ; Feicht, S. ; Djermanovic, K. ; Jagdhuber, F. ; Hömig-Hölzel, C. ; Ferch, U. ; Ruland, J. ; Rajewsky, K. ; Zimber-Strobl, U.
B cell expansion and lymphomagenesis induced by chronic CD40 signaling is strictly dependent on CD19.Graf, N. ; Li, Z. ; Herrmann, K. ; Weh, D. ; Aichler, M. ; Slawska, J. ; Walch, A.K. ; Peschel, C. ; Schwaiger, M. ; Buck, A.K. ; Dechow, T. ; Keller, U.
Positron emission tomographic monitoring of dual phosphatidylinositol-3-kinase and mTOR inhibition in anaplastic large cell lymphoma.Bussey, K. ; Reimer, E. ; Todt, H. ; Denker, B. ; Gallo, A. ; Konrad, A. ; Ottinger, M. ; Adler, H. ; Stürzl, M. ; Brune, W. ; Brinkmann, M.M.
The gammaherpesviruses Kaposi's sarcoma-associated herpesvirus and murine gammaherpesvirus 68 modulate the toll-like receptor-induced proinflammatory cytokine response.Yabal, M. ; Müller, N. ; Adler, H. ; Knies, N. ; Groß, C.J. ; Damgaard, R.B. ; Kanegane, H. ; Ringelhan, M. ; Kaufmann, T. ; Heikenwälder, M. ; Strasser, A. ; Groß, O. ; Ruland, J. ; Peschel, C. ; Gyrd-Hansen, M. ; Jost, P.J.
XIAP restricts TNF- and RIP3-dependent cell death and inflammasome activation.Ameres, S. ; Besold, K. ; Plachter, B. ; Moosmann, A.
CD8 T cell-evasive functions of human cytomegalovirus display pervasive MHC allele specificity, complementarity, and cooperativity.Gorzolka, K. ; Walch, A.K.
MALDI mass spectrometry imaging of formalin-fixed paraffin-embedded tissues in clinical research.Huber, K. ; Aichler, M. ; Sun, N. ; Buck, A. ; Li, Z. ; Fernandez, I.E. ; Hauck, S.M. ; Zitzelsberger, H. ; Eickelberg, O. ; Janssen, K.P. ; Keller, U. ; Walch, A.K.
A rapid ex vivo tissue model for optimising drug detection and ionisation in MALDI imaging studies.Dekker, T.J. ; Balluff, B.D. ; Jones, E.A. ; Schöne, C.D. ; Schmitt, M. ; Aubele, M. ; Kroep, J.R. ; Smit, V.T. ; Tollenaar, R.A. ; Mesker, W.E. ; Walch, A.K. ; McDonnell, L.A.
Multicenter Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging (MALDI MSI) identifies proteomic differences in breast-cancer-associated stroma.Bézière, N. ; von Schacky, C. ; Kosanke, Y. ; Kimm, M. ; Nunes, A. ; Licha, K. ; Aichler, M. ; Walch, A.K. ; Rummeny, E.J. ; Ntziachristos, V. ; Meier, R.
Optoacoustic imaging and staging of arthritic inflammation.Weller, P. ; Bankfalvi, A. ; Gu, X. ; Dominas, N. ; Lehnerdt, G.F. ; Zeidler, R. ; Lang, S. ; Brandau, S. ; Dumitru, C.A.
The role of tumour FoxP3 as prognostic marker in different subtypes of head and neck cancer.Kucharska, J. ; del Río, P. ; Arango-González, B. ; Gorza, M. ; Feuchtinger, A. ; Hauck, S.M. ; Ueffing, M.
Cyr61 activates retinal cells and prolongs photoreceptor survival in rd1 mouse model of retinitis pigmentosa.Maetzig, T. ; Kuehle, J. ; Schwarzer, A. ; Turan, S. ; Rothe, M. ; Chaturvedi, A. ; Morgan, M. ; Ha, T.C. ; Heuser, M. ; Hammerschmidt, W. ; Baum, C. ; Schambach, A.
All-in-One inducible lentiviral vector systems based on drug controlled FLP recombinase.Prägert, M.
TALE nucleases as antiviral factors.Stribl, C.B. ; Samara, A. ; Trümbach, D. ; Augustin, R. ; Neumann, M. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Rathkolb, B. ; Wolf, E. ; Beckers, J. ; Horsch, M. ; Neff, F. ; Kremmer, E. ; Koob, S. ; Reichert, A.S. ; Hans, W. ; Rozman, J. ; Klingenspor, M. ; Aichler, M. ; Walch, A.K. ; Becker, L. ; Klopstock, T. ; Glasl, L. ; Hölter, S.M. ; Wurst, W. ; Floß, T.
Mitochondrial dysfunction and decrease in body weight of a transgenic knock-in mouse model for TDP-43.Frankenberger, S. ; Davari, K. ; Fischer-Burkart, S. ; Böttcher, K. ; Tomi, N.S. ; Zimber-Strobl, U. ; Jungnickel, B.
Checkpoint kinase 1 negatively regulates somatic hypermutation.Sun, N. ; Ly, A. ; Meding, S. ; Witting, M. ; Hauck, S.M. ; Ueffing, M. ; Schmitt-Kopplin, P. ; Aichler, M. ; Walch, A.K.
High-resolution metabolite imaging of light and dark treated retina using MALDI-FTICR mass spectrometry.Gustems, M. ; Woellmer, A. ; Rothbauer, U. ; Eck, S.H. ; Wieland, T. ; Lutter, D. ; Hammerschmidt, W.
c-Jun/c-Fos heterodimers regulate cellular genes via a newly identified class of methylated DNA sequence motifs.Li, Z. ; Herrmann, K. ; Pirsig, S. ; Philipp-Abbrederis, K. ; Henninger, M. ; Aichler, M. ; Feuchtinger, A. ; Walch, A.K. ; Beer, A.J. ; Ringshausen, I. ; Pomykala, K.L. ; Scheidhauer, K. ; Schwaiger, M. ; Keller, U. ; Buck, A.K.
Molecular imaging for early prediction of response to Sorafenib treatment in sarcoma.Wildgruber, M. ; Bielicki, I. ; Aichler, M. ; Kosanke, K. ; Feuchtinger, A. ; Settles, M. ; Onthank, D.C. ; Cesati, R.R. ; Robinson, S.P. ; Huber, A.M. ; Rummeny, E.J. ; Walch, A.K. ; Botnar, R.M.
Assessment of myocardial infarction and post-infarction scar remodeling with an elastin-specific magnetic resonance agent.McDonnell, L.A. ; Walch, A.K. ; Stoeckli, M. ; Corthals, G.L.
MSiMass list: A public database of identifications for protein MALDI MSI.Aichler, M. ; Walch, A.K.
In brief: The (molecular) pathogenesis of Barrett's oesophagus.Vereide, D.T. ; Seto, E. ; Chiu, Y.F. ; Hayes, M. ; Tagawa, T. ; Grundhoff, A. ; Hammerschmidt, W. ; Sugden, B.
Epstein-Barr virus maintains lymphomas via its miRNAs.Frankenberger, S.
Die Rolle der Checkpoint-Kinase 1 in der Immunglobulin-Diversifizierung.Ameres, S.
The T cell repertoire specific for the IE-1 protein of human cytomegalovirus: Diversity, function and evasion.Ehrhardt, H. ; Wachter, F. ; Grunert, M. ; Jeremias, I.
TRAIL induces apoptosis preferentially in cell cycle arrested tumor cells, e.g., in tumor cells from children with acute lymphoblastic leukemia upon knockdown of cyclinE.Aichler, M.
Bildgebende MS in biomedizinischer Forschung und Diagnostik.Draeseke, A.
Deregulated notch and CD40 signaling in murine B lymphocytes.Martin, L.
Die spezifische T-Zellantwort gegen das humane Herpesvirus 6B.Frankó, A. ; Baris, O.R. ; Bergschneider, E. ; von Toerne, C. ; Hauck, S.M. ; Aichler, M. ; Walch, A.K. ; Wurst, W. ; Wiesner, R.J. ; Johnston, I.C.D. ; Hrabě de Angelis, M.
Efficient isolation of pure and functional mitochondria from mouse tissues using automated tissue disruption and enrichment with anti-TOM22 magnetic beads.Ehrhardt, H. ; Pfeiffer, S. ; Schrembs, D. ; Wachter, F. ; Grunert, M. ; Jeremias, I.
Activation of DNA damage response by antitumor therapy counteracts the activity of vinca alkaloids.Kim, J. ; Badaloni, A. ; Willert, T. ; Zimber-Strobl, U. ; Kühn, R. ; Wurst, W. ; Kieslinger, M.
An RNAi-based approach to down-regulate a gene family in vivo.Barros, M.H. ; Hauck, F. ; Dreyer, J.H. ; Kempkes, B. ; Niedobitek, G.
Macrophage polarisation: An immunohistochemical approach for identifying M1 and M2 macrophages.Giehler, F.
Etablierung der Interaktion des viralen Onkoproteins LMP1 mit den zellulären Signalproteinen der TRAF-Proteinfamilie als Zielstruktur für Inhibitoren.Gondi, G.
Einfluss eines Carboanhydrase XII-spezifischen Antikörpers auf das Tumorwachstum in vitro und in vivo sowie Onkosomen-basierte Generierung neuer tumorreaktiver Antikörper.Ale, A.B.F ; Siebenhaar, F. ; Kosanke, K. ; Aichler, M. ; Radrich, K. ; Heydrich, S. ; Schiemann, M. ; Bielicki, I. ; Noel, P.B. ; Braren, R. ; Maurer, M. ; Walch, A.K. ; Rummeny, E.J. ; Ntziachristos, V. ; Wildgruber, M.
Cardioprotective C-kit+ bone marrow cells attenuate apoptosis after acute myocardial infarction in mice – in-vivo assessment with fluorescence molecular imaging.Falkenberg, N. ; Anastasov, N. ; Rappl, K. ; Braselmann, H. ; Auer, G. ; Walch, A.K. ; Huber, M. ; Höfig, I. ; Schmitt, M. ; Höfler, H. ; Atkinson, M.J. ; Aubele, M.
MiR-221/-222 differentiate prognostic groups in advanced breast cancers and influence cell invasion.Hellert, J. ; Weidner-Glunde, M. ; Krausze, J. ; Richter, U. ; Adler, H. ; Fedorov, R. ; Pietrek, M. ; Rückert, J. ; Ritter, C. ; Schulz, T.F. ; Lührs, T.
A structural basis for BRD2/4-mediated host chromatin interaction and oligomer assembly of Kaposi sarcoma-associated herpesvirus and murine gammaherpesvirus LANA proteins.McClellan, M.J. ; Wood, C.D. ; Ojeniyi, O. ; Cooper, T.J. ; Kanhere, A. ; Arvey, A. ; Webb, H.M. ; Palermo, R.D. ; Harth-Hertle, M.L. ; Kempkes, B. ; Jenner, R.G. ; West, M.J.
Modulation of enhancer looping and differential gene targeting by Epstein-Barr virus transcription factors directs cellular reprogramming.Harth-Hertle, M.L. ; Scholz, B.A. ; Erhard, F. ; Glaser, L.V. ; Dölken, L. ; Zimmer, R. ; Kempkes, B.
Inactivation of intergenic enhancers by EBNA3A initiates and maintains polycomb signatures across a chromatin domain encoding CXCL10 and CXCL9.Altomonte, J. ; Marozin, S. ; de Toni, E.N. ; Rizzani, A. ; Esposito, I. ; Steiger, K. ; Feuchtinger, A. ; Hellerbrand, C. ; Schmid, R.M. ; Ebert, O.
Antifibrotic properties of transarterial oncolytic VSV therapy for hepatocellular carcinoma in rats with thioacetamide-induced liver fibrosis.Dumitru, C.A. ; Bankfalvi, A. ; Gu, X. ; Zeidler, R. ; Brandau, S. ; Lang, S.
AHNAK and inflammatory markers predict poor survival in laryngeal carcinoma.Dumitru, C.A. ; Bankfalvi, A. ; Gu, X. ; Eberhardt, W.E. ; Zeidler, R. ; Lang, S. ; Brandau, S.
Neutrophils Activate Tumoral CORTACTIN to Enhance Progression of Orohypopharynx Carcinoma.Gondi, G. ; Mysliwietz, J. ; Hulikova, A. ; Jen, J.P. ; Swietach, P. ; Kremmer, E. ; Zeidler, R.
Antitumor efficacy of a monoclonal antibody that inhibits the activity of cancer-associated carbonic anhydrase XII.Hahne, H. ; Pachl, F. ; Ruprecht, B. ; Maier, S.K. ; Klaeger, S. ; Helm, D. ; Médard, G. ; Wilm, M. ; Lemeer, S. ; Kuster, B.
DMSO enhances electrospray response, boosting sensitivity of proteomic experiments.Steinberger, J. ; Kontaxis, G. ; Rancan, C. ; Skern, T.
Comparison of self-processing of foot-and-mouth disease virus leader proteinase and porcine reproductive and respiratory syndrome virus leader proteinase nsp1α.Schmitt, S. ; Saathoff, F. ; Meissner, L. ; Schropp, E.-M. ; Lichtmannegger, J. ; Schulz, S. ; Eberhagen, C. ; Borchard, S. ; Aichler, M. ; Adamski, J. ; Plesnila, N. ; Rothenfusser, S. ; Kroemer, G. ; Zischka, H.
A semi-automated method for isolating functionally intact mitochondria from cultured cells and tissue biopsies.Pallua, J.D. ; Schaefer, G. ; Seifarth, C. ; Becker, M. ; Meding, S. ; Rauser, S. ; Walch, A.K. ; Handler, M. ; Netzer, M. ; Popovscaia, M. ; Osl, M. ; Baumgartner, C. ; Lindner, H. ; Kremser, L. ; Sarg, B. ; Bartsch, G. ; Huck, C.W. ; Bonn, G.K. ; Klocker, H.
MALDI-MS tissue imaging identification of biliverdin reductase B overexpression in prostate cancer.Sauter, D. ; Hotter, D. ; Engelhart, S. ; Giehler, F. ; Kieser, A. ; Kubisch, C. ; Kirchhoff, F.
A rare missense variant abrogates the signaling activity of tetherin/BST-2 without affecting its effect on virus release.Balluff, B.
MALDI imaging mass spectrometry in clinical proteomics research of gastric cancer tissues.Priglinger, C.S. ; Szober, C.M. ; Priglinger, S.G. ; Merl, J. ; Euler, K.N. ; Kernt, M. ; Gondi, G. ; Behler, J. ; Geerlof, A. ; Kampik, A. ; Ueffing, M. ; Hauck, S.M.
Galectin-3 induces clustering of CD147 and integrin-β1 transmembrane glycoprotein receptors on the RPE cell surface.Neubert, P. ; Walch, A.K.
Current frontiers in clinical research application of MALDI imaging mass spectrometry.Ehrhardt, H. ; Wachter, F. ; Grunert, M. ; Jeremias, I.
Cell cycle-arrested tumor cells exhibit increased sensitivity towards TRAIL-induced apoptosis.Woellmer, A. ; Hammerschmidt, W.
Epstein-Barr virus and host cell methylation: Regulation of latency, replication and virus reactivation.Wagner, F.M. ; Brizic, I. ; Prager, A. ; Trsan, T. ; Arapovic, M. ; Lemmermann, N.A.W. ; Podlech, J. ; Reddehase, M.J. ; Lemnitzer, F. ; Bosse, J.B. ; Gimpfl, M. ; Marcinowski, L. ; MacDonald, M. ; Adler, H. ; Koszinowski, U.H. ; Adler, B.
The viral chemokine MCK-2 of murine cytomegalovirus promotes infection as part of a gH/gL/MCK-2 complex.Berezowska, S. ; Novotny, A. ; Bauer, K. ; Feuchtinger, A. ; Slotta-Huspenina, J. ; Becker, K. ; Langer, R. ; Walch, A.K.
Association between HSP90 and Her2 in gastric and gastroesophageal carcinomas.Sun, N. ; Walch, A.K.
Qualitative and quantitative mass spectrometry imaging of drugs and metabolites in tissue at therapeutic levels.Jeliazkova, P. ; Jors, S. ; Lee, M. ; Zimber-Strobl, U. ; Ferrer, J. ; Schmid, R.M. ; Siveke, J.T. ; Geisler, F.
Canonical notch2 signaling determines biliary cell fates of embryonic hepatoblasts and adult hepatocytes independent of Hes1.Ameres, S. ; Mautner, J. ; Schlott, F. ; Neuenhahn, M. ; Busch, D.H. ; Plachter, B. ; Moosmann, A.
Presentation of an immunodominant immediate-early CD8+ T cell epitope resists human cytomegalovirus immunoevasion.Scholz, B.A. ; Harth-Hertle, M.L. ; Malterer, G. ; Haas, J. ; Ellwart, J. ; Schulz, T.F. ; Kempkes, B.
Abortive lytic reactivation of KSHV in CBF1/CSL deficient human B cell lines.Maier, S.K. ; Hahne, H. ; Moghaddas Gholami, A. ; Balluff, B. ; Meding, S. ; Schoene, C. ; Walch, A.K. ; Kuster, B.
Comprehensive identification of proteins from MALDI imaging.Wortmann, M. ; Schneider, M. ; Pircher, J. ; Hellfritsch, J. ; Aichler, M. ; Vegi, N. ; Koelle, P. ; Kuhlencordt, P. ; Walch, A.K. ; Pohl, U. ; Bornkamm, G.W. ; Conrad, M. ; Beck, H.
Combined deficiency in glutathione peroxidase 4 and vitamin E causes multi-organ thrombus formation and early death in mice.Wachter, F. ; Grunert, M. ; Blaj, C. ; Weinstock, D.M. ; Jeremias, I. ; Ehrhardt, H.
Impact of the p53 status of tumor cells on extrinsic and intrinsic apoptosis signaling.Schulz, S. ; Schmitt, S. ; Wimmer, R. ; Aichler, M. ; Eisenhofer, S. ; Lichtmannegger, J. ; Eberhagen, C. ; Artmann, R. ; Toókos, F. ; Walch, A.K. ; Krappmann, D. ; Brenner-Jan, C. ; Rust, C. ; Zischka, H.
Progressive stages of mitochondrial destruction caused by cell toxic bile salts.Taruttis, A. ; Wildgruber, M. ; Kosanke, K. ; Bézière, N. ; Licha, K. ; Haag, R. ; Aichler, M. ; Walch, A.K. ; Rummeny, E. ; Ntziachristos, V.
Multispectral optoacoustic tomography of myocardial infarction.Krebs, K.M. ; Böttinger, N. ; Huang, L.R. ; Chmielewski, M. ; Arzberger, S. ; Gasteiger, G. ; Jager, C. ; Schmitt, E. ; Bohne, F. ; Aichler, M. ; Uckert, W. ; Abken, H. ; Heikenwälder, M. ; Knolle, P. ; Protzer, U.
T cells expressing a chimeric antigen receptor that binds hepatitis B virus envelope proteins control virus replication in mice.Kreth, S. ; Limbeck, E. ; Hinske, L.C. ; Schütz, S.V. ; Thon, N. ; Hoefig, K.P. ; Egensperger, R. ; Kreth, F.W.
In human glioblastomas transcript elongation by alternative polyadenylation and miRNA targeting is a potent mechanism of MGMT silencing.Ludyga, N. ; Englert, S. ; Pflieger, K. ; Rauser, S. ; Braselmann, H. ; Walch, A.K. ; Auer, G. ; Höfler, H. ; Aubele, M.
The impact of Cysteine-Rich Intestinal Protein 1 (CRIP1) in human breast cancer.Azimzadeh, O. ; Sievert, W. ; Sarioglu, H. ; Yentrapalli, R. ; Barjaktarovic, Z. ; Sriharshan, A. ; Ueffing, M. ; Janik, D. ; Aichler, M. ; Atkinson, M.J. ; Multhoff, G. ; Tapio, S.
PPAR alpha: A novel radiation target in locally exposed Mus musculus heart revealed by quantitative proteomics.Tapfer, A. ; Braren, R. ; Bech, M. ; Willner, M. ; Zanette, I. ; Weitkamp, T. ; Trajkovic-Arsic, M. ; Siveke, J.T. ; Settles, M. ; Aichler, M. ; Walch, A.K. ; Pfeiffer, F.
X-ray phase-contrast CT of a pancreatic ductal adenocarcinoma mouse model.de Jong, S.J. ; Albrecht, J.-C. ; Giehler, F. ; Kieser, A. ; Sticht, H. ; Biesinger, B.
Noncanonical NF-κB activation by the oncoprotein Tio occurs through a nonconserved TRAF3-binding motif.Aichler, M. ; Elsner, M. ; Ludyga, N. ; Feuchtinger, A. ; Zangen, V. ; Maier, S.K. ; Balluff, B. ; Schöne, C. ; Hierber, L. ; Braselmann, H. ; Meding, S. ; Rauser, S. ; Zischka, H. ; Aubele, M. ; Schmitt, M. ; Feith, M. ; Hauck, S.M. ; Ueffing, M. ; Langer, R. ; Kuester, B. ; Zitzelsberger, H. ; Höfler, H. ; Walch, A.K.
Clinical response to chemotherapy in oesophageal adenocarcinoma patients is linked to defects in mitochondria.Ehrhardt, H. ; Pannert, L. ; Pfeiffer, S. ; Wachter, F. ; Amtmann, E. ; Jeremias, I.
Enhanced anti-tumour effects of vinca alkaloids given separately from cytostatic therapies.Chaves-Perez, A. ; Mack, B. ; Maetzel, D. ; Kremling, H. ; Eggert, C. ; Harréus, U. ; Gires, O.
EpCAM regulates cell cycle progression via control of cyclin D1 expression.Vidy, A. ; Sacher, T. ; Adler, H. ; Jordan, S. ; Koszinowski, U.H. ; Ruzsics, Z.
Systemic and local infection routes govern different cellular dissemination pathways during gammaherpesvirus infection in vivo.Canis, M. ; Lechner, A. ; Mack, B. ; Zengel, P. ; Laubender, R.P. ; Koehler, U. ; Heissmeyer, V. ; Gires, O.
CD133 induces tumour-initiating properties in HEK293 cells.Oetjen, J. ; Aichler, M. ; Trede, D. ; Strehlow, J. ; Berger, J. ; Heldmann, S. ; Becker, M. ; Gottschalk, M. ; Kobarg, J.H. ; Wirtz, S. ; Schiffler, S. ; Thiele, H. ; Walch, A.K. ; Maass, P. ; Alexandrov, T.
MRI-compatible pipeline for three-dimensional MALDI imaging mass spectrometry using PAXgene fixation.Hammerschmidt, W. ; Sugden, B.
Replication of Epstein-Barr viral DNA.Lankisch, P. ; Adler, H. ; Borkhardt, A.
Testing for herpesvirus infection is essential in children with chromosomal-instability syndromes.Schöne, C. ; Höfler, H. ; Walch, A.K.
MALDI imaging mass spectrometry in cancer research: Combining proteomic profiling and histological evaluation.Meding, S. ; Walch, A.K.
MALDI imaging mass spectrometry for direct tissue analysis.Hesse, J. ; Ameres, S. ; Besold, K. ; Krauter, S. ; Moosmann, A. ; Plachter, B.
Suppression of CD8+ T cell recognition in the immediate-early phase of human cytomegalovirus infection.Müller, T.D. ; Lee, S.J. ; Jastroch, M. ; Kabra, D. ; Stemmer, K. ; Aichler, M. ; Abplanalp, B. ; Ananthakrishnan, G. ; Bhardwaj, N. ; Collins, S. ; Divanovic, S. ; Endele, M. ; Finan, B. ; Gao, Y. ; Habegger, K.M. ; Hembree, J. ; Heppner, K.M. ; Hofmann, S. ; Holland, J. ; Küchler, D. ; Kutschke, M. ; Krishna, R. ; Lehti, M. ; Oelkrug, R. ; Ottaway, N. ; Perez-Tilve, D. ; Raver, C. ; Walch, A.K. ; Schriever, S.C. ; Speakman, J. ; Tseng, Y.H. ; Diaz-Meco, M. ; Pfluger, P.T. ; Moscat, J. ; Tschöp, M.H.
P62 links β-adrenergic input to mitochondrial function and thermogenesis.Höfig, K.P. ; Rath, N. ; Heinz, G.A. ; Wolf, C. ; Dameris, J. ; Schepers, A. ; Kremmer, E. ; Ansel, K.M. ; Heissmeyer, V.
Eri1 degrades the stem-loop of oligouridylated histone mRNAs to induce replication-dependent decay.Marinoni, I. ; Lee, M.S. ; Mountford, S. ; Perren, A. ; Bravi, I. ; Jennen, L. ; Feuchtinger, A. ; Drouin, J. ; Roncaroli, F. ; Pellegata, N.S.
Characterization of MENX-associated pituitary tumours.Bettstetter, M. ; Berezowska, S. ; Keller, G. ; Walch, A.K. ; Feuchtinger, A. ; Slotta-Huspenina, J. ; Feith, M. ; Drecoll, E. ; Höfler, H. ; Langer, R.
Epidermal growth factor receptor, phosphatidylinositol-3-kinase catalytic subunit/PTEN, and KRAS/NRAS/BRAF in primary resected esophageal adenocarcinomas: Loss of PTEN is associated with worse clinical outcome.Feicht, S.
Die Rolle der Raf-Kinasen in der B-Zell-Entwicklung und -Aktivierung.Wachter, F. ; Grunert, M. ; Jeremias, I. ; Ehrhardt, H.
TRAIL targets cell cycle arrested tumor cells.Strehle, M.L.
Aufklärung der Funktion virus-kodierter miRNAs während einer Gammaherpesvirus-Infektion anhand des murinen Gammaherpesvirus 68 (MHV-68) als Modell.Grunert, M.
Die Charakterisierung des rezeptornahen Signalweges der TRAIL-induzierten Aktivierung von NF-κB.Steinbrück, L.
The role of the herpesviral proteins LMP2A, K1, and K15 during oncogenic transformation of primary B cells.Town, J.A.
Functions of the germinal center kinase TNIK in signal transduction of the viral oncoprotein LMP1 and the related CD40 receptor.Hahne, H. ; Neubert, P. ; Kuhn, K. ; Etienne, C. ; Bomgarden, R. ; Rogers, J.C. ; Kuster, B.
Carbonyl-reactive tandem mass tags for the proteome-wide quantification of N-linked glycans.Canis, M. ; Lechner, A. ; Mack, B. ; Zengel, P. ; Laubender, R.P. ; Koehler, U. ; Heissmeyer, V. ; Gires, O.
CD133 is a predictor of poor survival in head and neck squamous cell carcinomas.Martin, L.K. ; Schub, A. ; Dillinger, S. ; Moosmann, A.
Specific CD8+ T cells recognize human herpesvirus 6B.Jochum, S. ; Moosmann, A. ; Lang, S. ; Hammerschmidt, W. ; Zeidler, R.
The EBV immunoevasins vIL-10 and BNLF2a protect newly infected B cells from immune recognition and elimination.Schrader, A. ; Meyer, K. ; von Bonin, F. ; Vockerodt, M. ; Walther, N. ; Hand, E. ; Ulrich, A. ; Matulewicz, K. ; Lenze, D. ; Hummel, M. ; Kieser, A. ; Engelke, M. ; Trümper, L. ; Kube, D.
Global gene expression changes of in vitro stimulated human transformed germinal centre B cells as surrogate for oncogenic pathway activation in individual aggressive B cell lymphomas.Terziyska, N. ; Alves, C.C. ; Groiss, V. ; Schneider, K. ; Farkasova, K. ; Ogris, M. ; Wagner, E. ; Ehrhardt, H. ; Brentjens, R.J. ; Zur Stadt, U. ; Horstmann, M. ; Quintanilla-Martinez, L. ; Jeremias, I.
In vivo imaging enables high resolution preclinical trials on patients' leukemia cells growing in mice.Feuerecker, B. ; Pirsig, S. ; Seidl, C. ; Aichler, M. ; Feuchtinger, A. ; Bruchelt, G. ; Senekowitsch-Schmidtke, R.
Lipoic acid inhibits cell proliferation of tumor cells in vitro and in vivo.Malinowsky, K. ; Wolff, C. ; Berg, D. ; Schuster, T. ; Walch, A.K. ; Bronger, H. ; Mannsperger, H. ; Schmidt, C. ; Korf, U. ; Höfler, H. ; Becker, K.F.
uPA and PAI-1-related signaling pathways differ between primary breast cancers and lymph node metastases.Gündisch, S. ; Boeckeler, E. ; Behrends, U. ; Amtmann, E. ; Ehrhardt, H. ; Jeremias, I.
Glucocorticoids augment survival and proliferation of tumor cells.Grunert, M. ; Gottschalk, K. ; Kapahnke, J. ; Gündisch, S. ; Kieser, A. ; Jeremias, I.
The adaptor protein FADD and the initiator caspase-8 mediate activation of NF-κB by TRAIL.Meding, S. ; Balluff, B. ; Elsner, M. ; Schöne, C. ; Rauser, S. ; Nitsche, U. ; Maak, M. ; Schäfer, A. ; Hauck, S.M. ; Ueffing, M. ; Langer, R. ; Höfler, H. ; Friess, H. ; Rosenberg, R. ; Walch, A.K.
Tissue-based proteomics reveals FXYD3, S100A11 and GSTM3 as novel markers for regional lymph node metastasis in colon cancer.Wulfkuhle, J.D. ; Berg, D. ; Wolff, C. ; Langer, R. ; Tran, K. ; Illi, J. ; Espina, V. ; Pierobon, M. ; Deng, J. ; Demichele, A. ; Walch, A.K. ; Bronger, H. ; Becker, I. ; Waldhör, C. ; Höfler, H. ; Esserman, L. ; Liotta, L.A. ; Becker, K.F. ; Petricoin, E.F.
Molecular analysis of HER2 signaling in human breast cancer by functional protein pathway activation mapping.Graf, N. ; Herrmann, K. ; Numberger, B. ; Zwisler, D. ; Aichler, M. ; Feuchtinger, A. ; Schuster, T. ; Wester, H.-J. ; Senekowitsch-Schmidtke, R. ; Peschel, C. ; Schwaiger, M. ; Keller, U. ; Dechow, T. ; Buck, A.K.
[18F]FLT is superior to [18F]FDG for predicting early response to antiproliferative treatment in high-grade lymphoma in a dose-dependent manner.Haneklaus, M. ; Gerlic, M. ; Kurowska-Stolarska, M. ; Rainey, A.A. ; Pich, D. ; McInnes, I.B. ; Hammerschmidt, W. ; O'Neill, L.A.J. ; Masters, S.L.
Cutting edge: MiR-223 and EBV miR-BART15 regulate the NLRP3 inflammasome and IL-1β production.Wöllmer, A. ; Arteaga-Salas, J.M. ; Hammerschmidt, W.
BZLF1 governs CpG-methylated chromatin of Epstein-Barr virus reversing epigenetic repression.Mayer, C.E. ; Geerlof, A. ; Schepers, A.
Efficient expression and purification of tag-free Epstein-Barr virus EBNA1 protein in Escherichia coli by auto-induction.Ruiss, R. ; Ohno, S. ; Steer, B. ; Zeidler, R. ; Adler, H.
Murine gammaherpesvirus 68 glycoprotein 150 does not contribute to latency amplification in vivo.Stross, L. ; Günther, J. ; Gasteiger, G. ; Asen, T. ; Graf, S. ; Aichler, M. ; Esposito, I. ; Busch, D.H. ; Knolle, P. ; Sparwasser, T. ; Protzer, U.
Foxp3+ regulatory T cells protect the liver from immune damage and compromise virus control during acute experimental hepatitis B virus infection in mice.Papior, P. ; Arteaga-Salas, J.M. ; Günther, T. ; Grundhoff, A. ; Schepers, A.
Open chromatin structures regulate the efficiencies of pre-RC formation and replication initiation in Epstein-Barr virus.Lehmann, F.M. ; Feicht, S. ; Helm, F. ; Maurberger, A. ; Ladinig, C. ; Zimber-Strobl, U. ; Kühn, R. ; Mautner, J. ; Gerbitz, A. ; Bornkamm, G.W.
Humanized c-Myc mouse.Slotta-Huspenina, J. ; Berg, D. ; Bauer, K. ; Wolff, C. ; Malinowsky, K. ; Bauer, L. ; Drecoll, E. ; Bettstetter, M. ; Feith, M. ; Walch, A.K. ; Höfler, H. ; Becker, K.F. ; Langer, R.
Evidence of prognostic relevant expression profiles of heat-shock proteins and glucose-regulated proteins in oesophageal adenocarcinomas.Vallon, M. ; Seidl, C. ; Blechert, B. ; Li, Z. ; Gilbertz, K.P. ; Baumgart, A. ; Aichler, M. ; Feuchtinger, A. ; Gaertner, F.C. ; Bruchertseifer, F. ; Morgenstern, A. ; Walch, A.K. ; Senekowitsch-Schmidtke, R. ; Essler, M.
Enhanced efficacy of combined 213Bi-DTPA-F3 and paclitaxel therapy of peritoneal carcinomatosis is mediated by enhanced induction of apoptosis and G2/M phase arrest.Li, Z. ; Graf, N.A. ; Herrmann, K. ; Jünger, A. ; Aichler, M. ; Feuchtinger, A. ; Baumgart, A. ; Walch, A.K. ; Peschel, C. ; Schwaiger, M. ; Buck, A. ; Keller, U. ; Dechow, T.
FLT-PET is superior to FDG-PET for very early response prediction in NPM-ALK-positive lymphoma treated with targeted therapy.Shkoda, A. ; Town, J.A. ; Griese, J. ; Romio, M. ; Sarioglu, H. ; Knöfel, T. ; Giehler, F. ; Kieser, A.
The germinal center kinase TNIK is required for canonical NF-κB and JNK signaling in B-cells by the EBV oncoprotein LMP1 and the CD40 receptor.Gehrmann, M. ; Stangl, S. ; Kirschner, A. ; Foulds, G.A. ; Sievert, W. ; Doß, B.T. ; Walch, A.K. ; Pockley, A.G. ; Multhoff, G.
Immunotherapeutic targeting of membrane Hsp70-expressing tumors using recombinant human granzyme B.Balluff, B. ; Rauser, S. ; Ebert, M.P. ; Siveke, J.T. ; Höfler, H. ; Walch, A.K.
Direct molecular tissue analysis by MALDI imaging mass spectrometry in the field of gastrointestinal disease.Saraste, A. ; Laitinen, I. ; Weidl, E. ; Wildgruber, M. ; Weber, A.W. ; Nekolla, S.G. ; Hölzlwimmer, G. ; Esposito, I. ; Walch, A.K. ; Leppänen, P. ; Lisinen, I. ; Luppa, P.B. ; Yla-Herttuala, S. ; Wester, H.J. ; Knuuti, J. ; Schwaiger, M.
Diet intervention reduces uptake of αvβ3 integrin-targeted PET tracer 18F-galacto-RGD in mouse atherosclerotic plaques.Ehrhardt, H. ; Höfig, I. ; Wachter, F. ; Obexer, P. ; Fulda, S. ; Terziyska, N. ; Jeremias, I.
NOXA as critical mediator for drug combinations in polychemotherapy.Trede, D. ; Schiffler, S. ; Becker, M. ; Wirtz, S. ; Steinhorst, K. ; Strehlow, J. ; Aichler, M. ; Kobarg, J.H. ; Oetjen, J. ; Dyatlov, A. ; Heldmann, S. ; Walch, A.K. ; Thiele, H. ; Maass, P. ; Alexandrov, T.
Exploring three-dimensional matrix-assisted laser desorption/ionization imaging mass spectrometry data: Three-dimensional spatial segmentation of mouse kidney.Baumhoer, D. ; Smida, J. ; Zillmer, S. ; Rosemann, M. ; Atkinson, M.J. ; Nelson, P.J. ; Jundt, G. ; von Luettichau, I. ; Nathrath, M.
Strong expression of CXCL12 is associated with a favorable outcome in osteosarcoma.Spranger, S. ; Jeremias, I. ; Wilde, S. ; Leisegang, M. ; Stärck, L. ; Mosetter, B. ; Uckert, W. ; Heemskerk, M.H. ; Schendel, D.J. ; Frankenberger, B.
TCR-transgenic lymphocytes specific for HMMR/Rhamm limit tumor outgrowth in vivo.Prade, E. ; Tobiasch, M. ; Hitkova, I. ; Schaffer, I. ; Lian, F. ; Xing, X.B. ; Tänzer, M. ; Rauser, S. ; Walch, A.K. ; Feith, M. ; Post, S. ; Röcken, C. ; Schmid, R.M. ; Ebert, M.P.A. ; Burgermeister, E.
Bile acids down-regulate caveolin-1 in esophageal epithelial cells through sterol responsive element-binding protein.Höfig, I. ; Ehrhardt, H. ; Jeremias, I.
Efficient RNA interference in patients' acute lymphoblastic leukemia cells amplified as xenografts in mice.Jochum, S. ; Ruiss, R. ; Moosmann, A. ; Hammerschmidt, W. ; Zeidler, R.
RNAs in Epstein-Barr virions control early steps of infection.Kalla, M. ; Göbel, C. ; Hammerschmidt, W.
The lytic phase of Epstein-Barr virus requires a viral genome with 5-methylcytosine residues in CpG sites.Grüner, B.M. ; Hahne, H. ; Mazur, P.K. ; Trajkovic-Arsic, M. ; Maier, S.K. ; Esposito, I. ; Kalideris, E. ; Michalski, C.W. ; Kleeff, J. ; Rauser, S. ; Schmid, R.M. ; Kuster, B. ; Walch, A.K. ; Siveke, J.T.
MALDI imaging mass spectrometry for in situ proteomic analysis of preneoplastic lesions in pancreatic cancer.Alves, C.C. ; Terziyska, N. ; Grunert, M. ; Gündisch, S. ; Graubner, U. ; Quintanilla-Martinez, L. ; Jeremias, I.
Leukemia-initiating cells of patient-derived acute lymphoblastic leukemia xenografts are sensitive toward TRAIL.Ohno, S. ; Steer, B. ; Sattler, C. ; Adler, H.
ORF23 of murine gammaherpesvirus 68 is non-essential for in vitro and in vivo infection.Heindl, S. ; Eggenstein, E. ; Keller, S. ; Kneissl, J. ; Keller, G. ; Mutze, K. ; Rauser, S. ; Gasteiger, G. ; Drexler, I. ; Hapfelmeier, A. ; Höfler, H. ; Luber, B.
Relevance of MET activation and genetic alterations of KRAS and E-cadherin for cetuximab sensitivity of gastric cancer cell lines.Seiz, L. ; Dorn, J. ; Kotzsch, M. ; Walch, A.K. ; Grebenchtchikov, N.I. ; Gkazepis, A. ; Schmalfeldt, B. ; Kiechle, M. ; Bayani, J. ; Diamandis, E.P. ; Langer, R. ; Sweep, F.C. ; Schmitt, M. ; Magdolen, V.
Stromal cell-associated expression of kallikrein-related peptidase 6 (KLK6) indicates poor prognosis of ovarian cancer patients.von Brühl, M.L. ; Stark, K. ; Steinhart, A. ; Chandraratne, S. ; Konrad, I. ; Lorenz, M. ; Khandoga, A. ; Tirniceriu, A. ; Coletti, R. ; Köllnberger, M. ; Byrne, R.A. ; Laitinen, I. ; Walch, A.K. ; Brill, A. ; Pfeiler, S. ; Manukyan, D. ; Braun, S. ; Lange, P. ; Riegger, J. ; Ware, J. ; Eckart, A. ; Haidari, S. ; Rudelius, M. ; Schulz, C. ; Echtler, K. ; Brinkmann, V. ; Schwaiger, M. ; Preissner, K.T. ; Wagner, D.D. ; Mackman, N. ; Engelmann, B. ; Massberg, S.
Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo.Manook, A. ; Yousefi, B.H. ; Willuweit, A. ; Platzer, S. ; Reder, S. ; Voss, A. ; Huisman, M. ; Settles, M. ; Neff, F. ; Velden, J. ; Schoor, M. ; von der Kammer, H. ; Wester, H.J. ; Schwaiger, M. ; Henriksen, G. ; Drzezga, A..
Small-animal PET imaging of amyloid-beta plaques with [11C]PiB and its multi-modal validation in an APP/PS1 mouse model of Alzheimer's disease.Grunewald, T.G. ; Ranft, A. ; Esposito, I. ; Da Silva-Buttkus, P. ; Aichler, M. ; Baumhoer, D. ; Schaefer, K.L. ; Ottaviano, L. ; Poremba, C. ; Jundt, G. ; Jürgens, H. ; Dirksen, U. ; Richter, G.H. ; Burdach, S.
High STEAP1 expression is associated with improved outcome of Ewing's sarcoma patients.Elsner, M. ; Rauser, S. ; Maier, S.K. ; Schöne, C. ; Balluff, B. ; Meding, S. ; Jung, G. ; Nipp, M. ; Sarioglu, H. ; Maccarrone, G. ; Aichler, M. ; Feuchtinger, A. ; Langer, R. ; Jütting, U. ; Feith, M. ; Kuster, B. ; Ueffing, M. ; Zitzelsberger, H. ; Höfler, H. ; Walch, A.K.
MALDI imaging mass spectrometry reveals COX7A2, TAGLN2 and S100-A10 as novel prognostic markers in Barrett's adenocarcinoma.Meding, S. ; Nitsche, U. ; Balluff, B. ; Elsner, M. ; Rauser, S. ; Schöne, C. ; Nipp, M. ; Maak, M. ; Feith, M. ; Ebert, M.P. ; Friess, H. ; Langer, R. ; Höfler, H. ; Zitzelsberger, H. ; Rosenberg, R. ; Walch, A.K.
Tumor classification of six common cancer types based on proteomic profiling by MALDI imaging.Takenaka, S. ; Möller, W. ; Semmler-Behnke, M. ; Karg, E.W. ; Wenk, A. ; Schmid, O. ; Stöger, T. ; Jennen, L. ; Aichler, M. ; Walch, A.K. ; Pokhrel, S. ; Mädler, L. ; Eickelberg, O. ; Kreyling, W.G.
Efficient internalization and intracellular translocation of inhaled gold nanoparticles in rat alveolar macrophages.Berg, D. ; Wolff, C. ; Malinowsky, K. ; Tran, K. ; Walch, A.K. ; Bronger, H. ; Schuster, T. ; Höfler, H. ; Becker, K.-F.
Profiling signalling pathways in formalin-fixed and paraffin-embedded breast cancer tissues reveals cross-talk between EGFR, HER2, HER3 and uPAR.Bonilla, W.V. ; Fröhlich, A. ; Senn, K. ; Kallert, S. ; Fernandez, M. ; Johnson, S. ; Kreutzfeldt, M. ; Hegazy, A.N. ; Schrick, C. ; Fallon, P.G. ; Klemenz, R. ; Nakae, S. ; Adler, H. ; Merkler, D. ; Löhning, M. ; Pinschewer, D.D.
The alarmin interleukin-33 drives protective antiviral CD8+ T cell responses.Ebert, M.P. ; Tänzer, M. ; Balluff, B. ; Burgermeister, E. ; Kretzschmar, A.K. ; Hughes, D.J. ; Tetzner, R. ; Lofton-Day, C. ; Rosenberg, R. ; Reinacher-Schick, A.C. ; Schulmann, K. ; Tannapfel, A. ; Hofheinz, R. ; Röcken, C. ; Keller, G. ; Langer, R. ; Specht, K. ; Porschen, R. ; Stöhlmacher-Williams, J. ; Schuster, T. ; Ströbel, P. ; Schmid, R.M.
TFAP2E-DKK4 and chemoresistance in colorectal cancer.Loder, S. ; Fakler, M. ; Schoeneberger, H. ; Cristofanon, S. ; Leibacher, J. ; Vanlangenakker, N. ; Bertrand, M.J. ; Vandenabeele, P. ; Jeremias, I. ; Debatin, K.M. ; Fulda, S.
RIP1 is required for IAP inhibitor-mediated sensitization of childhood acute leukemia cells to chemotherapy-induced apoptosis.Aichler, M. ; Seiler, C. ; Tost, M. ; Siveke, J. ; Mazur, P.K. ; Da Silva-Buttkus, P. ; Bartsch, D.K. ; Langer, P. ; Chiblak, S. ; Dürr, A. ; Höfler, H. ; Klöppel, G. ; Müller-Decker, K. ; Brielmeier, M. ; Esposito, I.
Origin of pancreatic ductal adenocarcinoma from atypical flat lesions: A comparative study in transgenic mice and human tissues.Kernt, M. ; Walch, A.K. ; Neubauer, A.S. ; Hirneiss, C. ; Haritoglou, C. ; Ulbig, M.W. ; Kampik, A.
Filtering blue light reduces light-induced oxidative stress, senescence, and accumulation of extracellular matrix proteins in human retinal pigment epithelium cells.Moosmann, A. ; Hammerschmidt, W. ; Kolb, H.-J.
Virus-specific T cells for therapy - approaches, problems, solutions.Kalla, M. ; Hammerschmidt, W.
Human B cells on their route to latent infection - early but transient expression of lytic genes of Epstein-Barr virus.Nipp, M. ; Elsner, M. ; Balluff, B. ; Meding, S. ; Sarioglu, H. ; Ueffing, M. ; Rauser, S. ; Unger, K. ; Höfler, H. ; Walch, A.K. ; Zitzelsberger, H.
S100-A10, thioredoxin, and S100-A6 as biomarkers of papillary thyroid carcinoma with lymph node metastasis identified by MALDI Imaging.Schmidl, S.
The role of AID and NF-κB for B cell development and lymphomagenesis.Luber, B. ; Deplazes, J. ; Keller, G. ; Walch, A.K. ; Rauser, S. ; Eichmann, M. ; Langer, R. ; Höfler, H. ; Hegewisch-Becker, S. ; Folprecht, G. ; Wöll, E. ; Decker, T.-M. ; Endlicher, E. ; Lorenzen, S. ; Fend, F. ; Peschel, C. ; Lordick, F.
Biomarker analysis of cetuximab plus oxaliplatin/leucovorin/5-fluorouracil in first-line metastatic gastric and oesophago-gastric junction cancer: Results from a phase II trial of the Arbeitsgemeinschaft Internistische Onkologie (AIO).Andratschke, M. ; Luebbers, C.W. ; Johannson, V. ; Schmitt, B. ; Mack, B. ; Zeidler, R. ; Lang, S. ; Wollenberg, B. ; Gildehaus, F.J.
Biodistribution of 131I-labeled anti-CK8 monoclonal antibody in HNSCC in xenotransplanted SCID mice.Baumhoer, D. ; Elsner, M. ; Smida, J. ; Zillmer, S. ; Rauser, S. ; Schoene, C. ; Balluff, B. ; Bielack, S. ; Jundt, G. ; Walch, A.K. ; Nathrath, M.
CRIP1 expression is correlated with a favorable outcome and less metastases in osteosarcoma patients.Pallua, J.D. ; Schaefer, G. ; Bittner, L.K. ; Pezzei, C. ; Huck-Pezzei, V. ; Schoenbichler, S.A. ; Meding, S. ; Rauser, S. ; Walch, A.K. ; Handler, M. ; Netzer, M. ; Osl, M. ; Seger, M. ; Pfeifer, B. ; Baumgartner, C. ; Lindner, H. ; Kremser, L. ; Sarg, B. ; Klocker, H. ; Bartsch, G. ; Bonn, G.K. ; Huck, C.W.
Matrix-assisted laser desorption-ionization imaging mass spectrometry for direct tissue analysis.Marjanovic, G. ; Schricker, M. ; Walch, A.K. ; zur Hausen, A. ; Hopt, U.T. ; Imdahl, A. ; Makowiec, F.
Detection of lymph node involvement by cytokeratin immunohistochemistry is an independent prognostic factor after curative resection of esophageal cancer.Walch, A.K. ; Rauser, S. ; Höfler, H.
MALDI imaging mass spectrometry on formalin-fixed paraffin-embedded tissues.Bergbauer, M.
Identifizierung von BZLF1-regulierten Promotoren des Epstein-Barr Virus.Fiedler, P.
Die Expression von LMP1, LMP2A und CD30 in B-Zellen zur Analyse physiologischer und pathogener Effekte.Jochum, S.
RNA transfer by Epstein-Barr virus triggers early events that regulate cell fate and promote immune evasion.Schmeinck, A.
Acquisition and loss of chromatin modifications during an Epstein-Barr Virus infection.Brittingham, S.
Downregulation of endogenous TRAIL and its effect on the human cancer cell line KELLY.Heinzelmann, K.
Das Kaposi-Sarkom assoziierte herpesvirale Protein vIRF4 als Interaktionspartner des zellulären DNA-Bindeproteins CBF1 und seine Rolle als transkriptioneller Regulator zellulärer Zielgene.Dumitru, C.A. ; Hoffmann, T.K. ; Lehnerdt, G. ; Zeidler, R. ; Lang, S. ; Brandau, S.
Moderne Methoden der Biomarkerentwicklung: eine Chance für die individualisierte Tumortherapie?Scholz, B.A.
Charakterisierung der Rolle des zellulären Transkriptionsfaktors CSL/CBF1 im lytischen Zyklus KSHV-infizierter B-Zellen.Horstkotte, J. ; Perisic, T. ; Schneider, M. ; Lange, P. ; Schroeder, M. ; Kiermayer, C. ; Hinkel, R. ; Ziegler, T. ; Mandal, P.K. ; David, R. ; Schulz, S. ; Schmitt, S. ; Widder, J. ; Sinowatz, F. ; Becker, B.F. ; Bauersachs, J. ; Naebauer, M. ; Franz, W.M. ; Jeremias, I. ; Brielmeier, M. ; Zischka, H. ; Conrad, M. ; Kupatt, C.
Mitochondrial thioredoxin reductase is essential for early postischemic myocardial protection.Ehrhardt, H. ; Schrembs, D. ; Moritz, C. ; Wachter, F. ; Haldar, S. ; Graubner, U. ; Nathrath, M. ; Jeremias, I.
Optimized anti-tumor effects of anthracyclines plus Vinca alkaloids using a novel, mechanism-based application schedule.Ehrhardt, H. ; Wachter, F. ; Maurer, M. ; Stahnke, K. ; Jeremias, I.
Important role of Caspase-8 for chemo-sensitivity of ALL cells.Schumann, R.G. ; Eibl, K.H. ; Zhao, F. ; Scheerbaum, M. ; Scheler, R. ; Schaumberger, M.M. ; Wehnes, H. ; Walch, A.K. ; Haritoglou, C. ; Kampik, A. ; Gandorfer, A.
Immunocytochemical and ultrastructural evidence of glial cells and hyalocytes in internal limiting membrane specimens of idiopathic macular holes.Laukens, B. ; Jennewein, C. ; Schenk, B. ; Vanlangenakker, N. ; Schier, A. ; Cristofanon, S. ; Zobel, K. ; Deshayes, K. ; Vucic, D. ; Jeremias, I. ; Bertrand, M.J. ; Vandenabeele, P. ; Fulda, S.
Smac mimetic bypasses apoptosis resistance in FADD- or caspase-8-deficient cells by priming for tumor necrosis factor α-induced necroptosis.Loos, M. ; Langer, R. ; Schuster, T. ; Gertler, R. ; Walch, A.K. ; Rauser, S. ; Friess, H. ; Feith, M.
Clinical significance of the costimulatory molecule B7-H1 in Barrett carcinoma.Zischka, H. ; Lichtmannegger, J. ; Schmitt, S. ; Jägemann, N. ; Schulz, S. ; Wartini, D. ; Jennen, L. ; Rust, C. ; Larochette, N. ; Galluzzi, L. ; Chajes, V. ; Bandow, N. ; Gilles, V.S. ; DiSpirito, A.A. ; Esposito, I. ; Göttlicher, M. ; Summer, K.H. ; Kroemer, G.
Liver mitochondrial membrane crosslinking and destruction in a rat model of Wilson disease.Ruiss, R. ; Jochum, S. ; Wanner, G. ; Reisbach, G. ; Hammerschmidt, W. ; Zeidler, R.
A virus-like particle-based Epstein-Barr virus vaccine.Balluff, B. ; Schöne, C. ; Höfler, H. ; Walch, A.K.
MALDI imaging mass spectrometry for direct tissue analysis: Technological advancements and recent applications.Lian, F. ; Xing, X. ; Yuan, G. ; Schäfer, C. ; Rauser, S. ; Walch, A.K. ; Röcken, C. ; Ebeling, M. ; Wright, M.B. ; Schmid, R.M. ; Ebert, M.P. ; Burgermeister, E.
Farnesoid X receptor protects human and murine gastric epithelial cells against inflammation-induced damage.Alexandrov, T. ; Meding, S. ; Trede, D. ; Kobarg, J.H. ; Balluff, B. ; Walch, A.K. ; Thiele, H. ; Maass, P.
Super-resolution segmentation of imaging mass spectrometry data: Solving the issue of low lateral resolution.Wu, Z. ; Doondeea, J.B. ; Moghaddas Gholami, A. ; Janning, M.C. ; Lemeer, S. ; Kramer, K. ; Eccles, S.A. ; Gollin, S.M. ; Grenman, R. ; Walch, A.K. ; Feller, S.M. ; Kuster, B.
Quantitative chemical proteomics reveals new potential drug targets in head and neck cancer.Lipps, H.J. ; Hammerschmidt, W. ; Ehrhardt, A.
Lebenslange Heilung mittels Gentransfer - Realität oder Utopie? Stabiler versus transienter Gentransfer.Mendiburo, M.J. ; Padeken, J. ; Fülöp, S. ; Schepers, A. ; Heun, P.
Drosophila CENH3 is sufficient for centromere formation.Thomae, A.W. ; Baltin, J. ; Pich, D. ; Deutsch, M.J. ; Ravasz, M. ; Zeller, K. ; Gossen, M. ; Hammerschmidt, W. ; Schepers, A.
Different roles of the human Orc6 protein in the replication initiation process.Balluff, B. ; Rauser, S. ; Meding, S. ; Elsner, M. ; Schöne, C. ; Feuchtinger, A. ; Schuhmacher, C. ; Novotny, A. ; Jütting, U. ; Maccarrone, G. ; Sarioglu, H. ; Ueffing, M. ; Braselmann, H. ; Zitzelsberger, H. ; Schmid, R.M. ; Höfler, H. ; Ebert, M.P. ; Walch, A.K.
MALDI imaging identifies prognostic seven-protein signature of novel tissue markers in intestinal-type gastric cancer.Hampel, F. ; Ehrenberg, S. ; Hojer, C. ; Draeseke, A. ; Marschall-Schröter, G. ; Kühn, R. ; Mack, B. ; Gires, O. ; Vahl, C.J. ; Schmidt-Supprian, M. ; Strobl, L.J. ; Zimber-Strobl, U.
CD19-independent instruction of murine marginal zone B-cell development by constitutive Notch2 signaling.Ruiss, R. ; Jochum, S. ; Mocikat, R. ; Hammerschmidt, W. ; Zeidler, R.
EBV-gp350 confers B-cell tropism to tailored exosomes and is a neo-antigen in normal and malignant B cells - a new option for the treatment of B-CLL.Langer, R. ; Rauser, S. ; Feith, M. ; Nährig, J.M. ; Feuchtinger, A. ; Friess, H. ; Höfler, H. ; Walch, A.K.
Assessment of ErbB2 (Her2) in oesophageal adenocarcinomas: Summary of a revised immunohistochemical evaluation system, bright field double in situ hybridisation and fluorescence in situ hybridisation.Timme, S. ; Schmitt, E. ; Stein, S. ; Schwarz-Finsterle, J. ; Wagner, J. ; Walch, A.K. ; Werner, M. ; Hausmann, M. ; Wiech, T.
Nuclear position and shape deformation of chromosome 8 territories in pancreatic ductal adenocarcinoma.Deininger, S.O. ; Cornett, D.S. ; Paape, R. ; Becker, M. ; Pineau, C. ; Rauser, S. ; Walch, A.K. ; Wolski, E.
Normalization in MALDI-TOF imaging datasets of proteins: Practical considerations.Ott, E. ; Norio, P. ; Ritzi, M. ; Schildkraut, C. ; Schepers, A.
The dyad symmetry element of Epstein-Barr virus is a dominant but dispensable replication origin.Hammerschmidt, W.
What keeps the power on in lymphomas? (Comment on Vereide and Sudgen, page 1977)Köchert, K. ; Ullrich, K. ; Kreher, S. ; Aster, J.C. ; Kitagawa, M. ; Jöhrens, K. ; Anagnostopoulos, I. ; Jundt, F. ; Lamprecht, B. ; Zimber-Strobl, U. ; Stein, H. ; Janz, M. ; Dörken, B. ; Mathas, S.
High-level expression of Mastermind-like 2 contributes to aberrant activation of the NOTCH signaling pathway in human lymphomas.Turchinovich, G. ; Vu, T.T. ; Frommer, F. ; Kranich, J. ; Schmid, S. ; Alles, M. ; Loubert, J.B. ; Goulet, J.P. ; Zimber-Strobl, U. ; Schneider, P. ; Bachl, J. ; Pearson, R. ; Crossley, M. ; Agenès, F. ; Kirberg, J.
Programming of marginal zone B-cell fate by basic Krüppel-like factor (BKLF/KLF3).Vela-Chávez, T. ; Adam, P. ; Kremer, M. ; Bink, K. ; Bacon, C.M. ; Menon, G. ; Ferry, J.A. ; Fend, F. ; Jaffe, E.S. ; Quintanilla-Martinez, L.
Cyclin D1 positive diffuse large B-cell lymphoma is a post-germinal center-type lymphoma without alterations in the CCND1 gene locus.Berg, D. ; Langer, R. ; Tran, K. ; Walch, A.K. ; Schuster, T. ; Bronger, H. ; Becker, K.F.
Protein microarray-based comparison of HER2, estrogen receptor, and progesterone receptor status in core biopsies and surgical specimens from FFPE breast cancer tissues.Eberhardt, C. ; Amann, B. ; Feuchtinger, A. ; Hauck, S.M. ; Deeg, C.A.
Differential expression of inwardly rectifying K+ channels and aquaporins 4 and 5 in autoimmune uveitis indicates misbalance in Müller glial cell-dependent ion and water homeostasis.Battke, C. ; Kremmer, E. ; Mysliwietz, J. ; Gondi, G. ; Dumitru, C. ; Brandau, S. ; Lang, S. ; Vullo, D. ; Supuran, C. ; Zeidler, R.
Generation and characterization of the first inhibitory antibody targeting tumour-associated carbonic anhydrase XII.Battke, C. ; Ruiss, R. ; Welsch, U. ; Wimberger, P. ; Lang, S. ; Jochum, S. ; Zeidler, R.
Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC.Jantscher, F. ; Pirker, C. ; Mayer, C.E. ; Berger, W. ; Sutterluety, H.
Overexpression of Aurora-A in primary cells interferes with S-phase entry by diminishing Cyclin D1 dependent activities.Sibbing, D. ; Pfeufer, A. ; Perisic, T. ; Mannes, A.M. ; Fritz-Wolf, K. ; Unwin, S. ; Sinner, M.F. ; Gieger, C. ; Gloeckner, C.J. ; Wichmann, H.-E. ; Kremmer, E. ; Schäfer, Z. ; Walch, A.K. ; Hinterseer, M. ; Näbauer, M. ; Kääb, S. ; Kastrati, A. ; Schömig, A. ; Meitinger, T. ; Bornkamm, G.W. ; Conrad, M. ; von Beckerath, N.
Mutations in the mitochondrial thioredoxin reductase gene TXNRD2 cause dilated cardiomyopathy.Saarikangas, J. ; Mattila, PK. ; Varjosalo, M. ; Bovellan, M. ; Hakanen, J. ; Calzada-Wack, J. ; Tost, M. ; Jennen, L. ; Rathkolb, B. ; Hans, W. ; Horsch, M. ; Hyvönen, M.E. ; Perälä, N. ; Fuchs, H. ; Gailus-Durner, V. ; Esposito, I. ; Wolf, E. ; Hrabě de Angelis, M. ; Frilander, MJ. ; Savilahti, H. ; Sariola, H. ; Sainio, K. ; Lehtonen, S. ; Taipale, J. ; Salminen, M. ; Lappalainen, P.
Missing-in-metastasis MIM/MTSS1 promotes actin assembly at intercellular junctions and is required for integrity of kidney epithelia.Lückerath, K. ; Kirkin, V. ; Melzer, I.M. ; Thalheimer, F.B. ; Siele, D. ; Milani, W. ; Adler, T. ; Aguilar-Pimentel, J.A. ; Horsch, M. ; Michel, G. ; Beckers, J. ; Busch, D.H. ; Ollert, M. ; Gailus-Durner, V. ; Fuchs, H. ; Hrabě de Angelis, M. ; Staal, F.J. ; Rajalingam, K. ; Hueber, A.O. ; Strobl, L.J. ; Zimber-Strobl, U. ; Zörnig, M.
Immune modulation by Fas ligand reverse signaling: Lymphocyte proliferation is attenuated by the intracellular Fas ligand domain.Lagarrigue, M. ; Becker, M. ; Lavigne, R. ; Deininger, S.O. ; Walch, A.K. ; Aubry, F. ; Suckau, D. ; Pineau, C.
Revisiting rat spermatogenesis with MALDI imaging at 20- μm resolution.Wolff, C. ; Malinowsky, K. ; Berg, D. ; Schragner, K. ; Schuster, T: ; Walch, A.K. ; Bronger, H. ; Höfler, H. ; Becker, K.F.
Signalling networks associated with urokinase-type plasminogen activator (uPA) and its inhibitor PAI-1 in breast cancer tissues: New insights from protein microarray analysis.Stangl, S. ; Gehrmann, M. ; Dressel, R. ; Alves, F. ; Dullin, C. ; Themelis, G. ; Ntziachristos, V. ; Staeblein, E. ; Walch, A.K. ; Winkelmann, I. ; Multhoff, G.
In vivo imaging of CT26 mouse tumours by using cmHsp70.1 monoclonal antibody.Rauser, S. ; Deininger, S.O. ; Suckau, D. ; Höfler, H. ; Walch, A.K.
Approaching MALDI molecular imaging for clinical proteomic research: Current state and fields of application.Papior, P.
Die Ausbildung von Pre-Replikationskomplexen im Epstein-Barr-Virus und dem Menschen: Eine Genom-weite Analyse.Höfig, I.
Mechanismen der Apoptoseinduktion: Betulinsäure in Kombination mit konventionellen Zytostatika auf Leukämiezellen.Iskra, S.
Angeborene und adaptive Immunreaktionen in der Frühphase der Epstein-Barr-Virus-Infektion.Medele, S.
Das Latente Membranprotein 2A des Epstein-Barr Virus und der humane B-Zell-Rezeptor: Ein Vergleich.Ruiss, R.
Induktion Epstein-Barr Virus-spezifischer Immunantworten durch Exosomen und Virus-like Particles.Schub, A.
Herpesvirusspezifische T-Zellen für die Immuntherapie: Von ihrer Identifikation zum Transfer ihrer Spezifität.Gündisch, S.
Glucocorticoid-induziertes Wachstum von Tumorzellen: Systematische Quantifizierung, Signalmechanismen und Inhibition.Lehnerdt, G. ; Hoffmann, T.K. ; Mattheis, S. ; Brandau, S. ; Zeidler, R. ; Lang, S.
[Diagnostic and prognostic biomarkers in head and neck squamous cell carcinoma].Balluf, B. ; Herrmann, K. ; Höfler, H. ; Walch, A.K. ; Ebert, M.
Classification of HER2/neu Status in Gastric cancer using a Breast Cancer Derived Proteome Classifier.Jochum, S. ; Zeidler, R.
The impact of BCRF1 (viral IL-10) and BNLF2a on the immune evasion of Epstein Barr Virus.Ergin, B. ; Meding, S. ; Langer, R. ; Kap, M. ; Viertler, C. ; Schott, C. ; Ferch, U. ; Riegman, P. ; Zatloukal, K. ; Walch, A.K. ; Becker, K.F.
Proteomic analysis of PAXgene-fixed tissues.Kempkes, B.
EBNA-2 in Transcription activation of viral and cellular.Rauser, S. ; Langer, R. ; Tschernitz, S. ; Gais, P. ; Jütting, U. ; Feith, M. ; Höfler, H. ; Walch, A.K.
High number of CD45RO+ tumor infiltrating lymphocytes is an independent prognostic factor in non-metastasized (stage I-IIA) esophageal adenocarcinoma.Heinzelmann, K. ; Scholz, B.A. ; Nowak, A. ; Fossum, E. ; Kremmer, E. ; Haas, J. ; Frank, R. ; Kempkes, B.
Kaposi's sarcoma-associated herpesvirus viral interferon regulatory factor 4 (vIRF4/K10) is a novel interaction partner of CSL/CBF1, the major downstream effector of Notch signaling.Seto, E. ; Moosmann, A. ; Grömminger, S. ; Walz, N. ; Grundhoff, A. ; Hammerschmidt, W.
Micro RNAs of Epstein-Barr virus promote cell cycle progression and prevent apoptosis of primary human B cells.Iskra, S. ; Kalla, M. ; Delecluse, H.J. ; Hammerschmidt, W. ; Moosmann, A.
Toll-like receptor agonists synergistically increase proliferation and activation of B cells by Epstein-Barr virus.Hipp, S. ; Berg, D. ; Ergin, B. ; Schuster, T. ; Hapfelmeier, A. ; Walch, A.K. ; Avril, S. ; Schmalfeldt, B. ; Höfler, H. ; Becker, K.F.
Interaction of Snail and p38 mitogen-activated protein kinase results in shorter overall survival of ovarian cancer patients.Herbert, Z. ; Rauser, S. ; Williams, L. ; Kapan, N. ; Güntner, M: ; Walch, A.K. ; Boyan, G.
Developmental expression of neuromodulators in the central complex of the grasshopper Schistocerca gregaria.Becker, K.-F. ; Berg, D. ; Malinowsky, K. ; Wolff, C. ; Ergin, B. ; Meding, S. ; Walch, A.K. ; Höfler, H.
Neues zur Proteinanalytik archivierter Gewebeproben.Ehm, O.K.H. ; Göritz, C. ; Covic, M. ; Schäffner, I. ; Schwarz, T.J. ; Karaca, E. ; Kempkes, B. ; Kremmer, E. ; Pfrieger, F.W. ; Espinosa, L. ; Bigas, A. ; Giachino, C. ; Taylor, V. ; Frisen, J. ; Lie, D.C.
RBPJκ-dependent signaling is essential for long-term maintenance of neural stem cells in the adult hippocampus.Yenamandra, S.P. ; Hellmann, U. ; Kempkes, B. ; Darekar, S.D. ; Petermann, S. ; Sculley, T. ; Klein, G. ; Kashuba, E.
Epstein-Barr virus encoded EBNA-3 binds to vitamin D receptor and blocks activation of its target genes.Mazur, P.K. ; Einwächter, H. ; Lee, M. ; Sipos, B. ; Nakhai, H. ; Rad, R. ; Zimber-Strobl, U. ; Strobl, L.J. ; Radtke, F. ; Klöppel, G. ; Schmid, R.M. ; Siveke, J.T.
Notch2 is required for progression of pancreatic intraepithelial neoplasia and development of pancreatic ductal adenocarcinoma.Pechloff, K. ; Holch, J. ; Ferch, U. ; Schweneker, M. ; Brunner, K. ; Kremer, M. ; Sparwasser, T. ; Quintanilla-Martinez, L. ; Zimber-Strobl, U. ; Streubel, B. ; Gewies, A. ; Peschel, C. ; Ruland, J.
The fusion kinase ITK-SYK mimics a T cell receptor signal and drives oncogenesis in conditional mouse models of peripheral T cell lymphoma.Mazur, P.K. ; Grüner, B.M. ; Nakhai, H. ; Sipos, B. ; Zimber-Strobl, U. ; Strobl, L.J. ; Radtke, F. ; Schmid, R.M. ; Siveke, J.T.
Identification of epidermal pdx1 expression discloses different roles of notch1 and notch2 in murine KrasG12D-induced skin carcinogenesis in vivo.Hauck, S.M. ; Dietter, J. ; Kramer, R.L. ; Hofmaier, F. ; Zipplies, J.K. ; Amann, B. ; Feuchtinger, A. ; Deeg, C.A. ; Ueffing, M.
Deciphering membrane-associated molecular processes in target tissue of autoimmune uveitis by label-free quantitative mass spectrometry.Bergbauer, M. ; Kalla, M. ; Schmeinck, A. ; Göbel, C. ; Rothbauer, U. ; Eck, S. ; Benet-Pagès, A. ; Strom, T.M. ; Hammerschmidt, W.
CpG-methylation regulates a class of Epstein-Barr virus promoters.Rüschoff, J. ; Dietel, M. ; Baretton, G. ; Arbogast, S. ; Walch, A.K. ; Monges, G. ; Chenard, M.-P. ; Penault-Llorca, F. ; Nagelmeier, I. ; Schlake, W. ; Höfler, H. ; Kreipe, H.H.
HER2 diagnostics in gastric cancer-guideline validation and development of standardized immunohistochemical testing.Smida, J. ; Baumhoer, D. ; Rosemann, M. ; Walch, A.K. ; Bielack, S. ; Poremba, C. ; Remberger, K. ; Korsching, E. ; Scheurlen, W. ; Dierkes, C. ; Burdach, S. ; Jundt, G. ; Atkinson, M.J. ; Nathrath, M.
Genomic alterations and allelic imbalances are strong prognostic predictors in osteosarcoma.Aubele, M. ; Spears, M. ; Ludyga, N. ; Braselmann, H. ; Feuchtinger, A. ; Taylor, K.J. ; Lindner, K. ; Auer, G. ; Stering, K. ; Höfler, H. ; Schmitt, M. ; Bartlett, J.M.S.
In situ quantification of HER2-protein tyrosine kinase 6 (PTK6) protein-protein complexes in paraffin sections from breast cancer tissues.Kalla, M. ; Schmeinck, A. ; Bergbauer, M. ; Pich, D. ; Hammerschmidt, W.
AP-1 homolog BZLF1 of Epstein-Barr virus has two essential functions dependent on the epigenetic state of the viral genome.Deutsch, M.J. ; Ott, E. ; Papior, P. ; Schepers, A.
The latent origin of replication of Epstein-Barr virus directs viral genomes to active regions of the nucleus.Schepers, A. ; Papior, P.
Why are we where we are? Understanding replication origins and initiation sites in eukaryotes using ChIP-approaches.Entschladen, F. ; Altschmied, J. ; Baumgrass, R. ; Behrmann, I. ; Giehl, K. ; Hermanns, H. ; Kieser, A. ; Klotz, L.O. ; Kubatzky, K.F. ; Hass, R. ; Janssen, O. ; Friedrich, K.
Signal transduction, receptors, mediators and genes: Younger than ever - the 13th meeting of the Signal Transduction Society focused on aging and immunology.Rauser, S. ; Marquardt, C. ; Balluff, B. ; Deininger, S.O. ; Albers, C. ; Belau, E. ; Hartmer, R. ; Suckau, D. ; Specht, K. ; Ebert, M.P. ; Schmitt, M. ; Aubele, M. ; Höfler, H. ; Walch, A.K.
Classification of HER2 receptor status in breast cancer tissues by MALDI imaging mass spectrometry.Echtler, K. ; Stark, K. ; Lorenz, M. ; Kerstan, S. ; Walch, A.K. ; Jennen, L. ; Rudelius, M. ; Seidl, S. ; Kremmer, E. ; Emambokus, N.R. ; von Bruehl, M.L. ; Frampton, J. ; Isermann, B. ; Genzel-Boroviczény, O. ; Schreiber, C. ; Mehilli, J. ; Kastrati, A. ; Schwaiger, M. ; Shivdasani, R.A. ; Massberg, S.
Platelets contribute to postnatal occlusion of the ductus arteriosus.Gross, H. ; Barth, S. ; Palermo, R.D. ; Mamiani, A. ; Hennard, C. ; Zimber-Strobl, U. ; West, M.J. ; Kremmer, E. ; Grässer, F.A.
Asymmetric Arginine dimethylation of Epstein-Barr virus nuclear antigen 2 promotes DNA targeting.Loeder, S. ; Drensek, A. ; Jeremias, I. ; Debatin, K.M. ; Fulda, S.
Small molecule XIAP inhibitors sensitize childhood acute leukemia cells for CD95-induced apoptosis.Unger, K. ; Wienberg, J. ; Riches, A. ; Hieber, L. ; Walch, A.K. ; Brown, A. ; O'Brien, P.C. ; Briscoe, C. ; Gray, L. ; Rodriguez, E. ; Jackl, G. ; Knijnenburg, J. ; Tallini, G. ; Ferguson-Smith, M. ; Zitzelsberger, H.
Novel gene rearrangements in transformed breast cells identified by high-resolution breakpoint analysis of chromosomal aberrations.Shyla, A. ; Hölzlwimmer, G. ; Calzada-Wack, J. ; Bink, K. ; Tischenko, O. ; Guilly, M.N. ; Chevillard, S. ; Samson, E. ; Graw, J. ; Atkinson, M.J. ; Pellegata, N.S.
Allelic loss of chromosomes 8 and 19 in MENX-associated rat pheochromocytoma.Laitinen, I. ; Saraste, A. ; Weidl, E. ; Poethko, T. ; Weber, A.W. ; Nekolla, S.G. ; Leppänen, P. ; Yla-Herttuala, S. ; Hölzlwimmer, G. ; Walch, A.K. ; Esposito, I. ; Wester, H.J. ; Knuuti, J. ; Schwaiger, M.
Evaluation of ανβ₃ integrin-targeted positron emission tomography tracer ¹⁸F-galacto-RGD for imaging of vascular inflammation in atherosclerotic mice.Rieger, S. ; Senghaas, N. ; Walch, A.K. ; Köster, R.W.
Cadherin-2 controls directional chain migration of cerebellar granule neurons.Schub, A. ; Schuster, I.G. ; Hammerschmidt, W. ; Moosmann, A.
CMV-specific TCR-transgenic T cells for immunotherapy.Hipp, S. ; Walch, A.K. ; Schuster, T. ; Losko, S. ; Laux, H. ; Bolton, T. ; Höfler, H. ; Becker, K.F.
Activation of epidermal growth factor receptor results in snail protein but not mRNA over-expression in endometrial cancer.Fakler, M. ; Loeder, S. ; Vogler, M. ; Schneider, K. ; Jeremias, I. ; Debatin, K.-M. ; Fulda, S.
Small molecule XIAP inhibitors cooperate with TRAIL to induce apoptosis in childhood acute leukemia cells and overcome Bcl-2-mediated resistance.Hertle, M.L. ; Popp, C. ; Petermann, S. ; Maier, S. ; Kremmer, E. ; Lang, R. ; Mages, J. ; Kempkes, B.
Differential gene expression patterns of EBV infected EBNA-3A positive and negative human B lymphocytes.Friedrich, K. ; Lindquist, J.A. ; Entschladen, F. ; Serfling, E. ; Thiel, G. ; Kieser, A. ; Gieh, K. ; Ehrhardt, C. ; Feller, S.M. ; Ullrich, O. ; Schaper, F. ; Janssen, O. ; Hass, R.
Signal transduction in the footsteps of Goethe and Schiller.Landmeier, S. ; Altvater, B. ; Pscherer, S. ; Juergens, H. ; Varnholt, L. ; Hansmeier, A. ; Bollard, C.M. ; Moosmann, A. ; Bisping, G. ; Rossig, C.
Activated human γδ T cells as stimulators of specific CD8⁺ T-cell responses to subdominant Epstein Barr virus epitopes: Potential for immunotherapy of cancer.Becker, K.F. ; Walch, A.K. ; Ueffing, M.
Protein analysis of tissues - current views and clinical perspectives.Rauser, S. ; Höfler, H. ; Walch, A.K.
In-situ-Proteomanalyse von Geweben: Mittels bildgebender Massenspektrometrie (MALDI Imaging)Lohmann, C. ; Muschaweckh, A. ; Kirschnek, S. ; Jennen, L. ; Wagner, H. ; Häcker, G.
Induction of tumor cell apoptosis or necrosis by conditional expression of cell death proteins: Analysis of cell death pathways and in vitro immune stimulatory potential.Faumont, N. ; Durand-Panteix, S. ; Schlee, M. ; Grömminger, S. ; Schuhmacher, M. ; Hölzel, M. ; Laux, G. ; Mailhammer, R. ; Rosenwald, A. ; Staudt, L.M. ; Bornkamm, G.W. ; Feuillard, J.
C-Myc and Rel/NF-κB are the two master transcriptional systems activated in the latency III program of Epstein-Barr virus-immortalized B cells.Aubele, M. ; Vidojkovic, S. ; Braselmann, H. ; Ritterswürden, D. ; Auer, G. ; Atkinson, M.J. ; Tapio, S. ; Höfler, H. ; Rauser, S. ; Bartlett, J.M.
Overexpression of PTK6 (breast tumor kinase) protein - a prognostic factor for long-term breast cancer survival - is not due to gene amplification.Kohlhof, H. ; Hampel, F. ; Hoffmann, R. ; Burtscher, H. ; Weidle, U.H. ; Hölzel, M. ; Eick, D. ; Zimber-Strobl, U. ; Strobl, L.J.
Notch1, Notch2, and Epstein-Barr virus-encoded nuclear antigen 2 signaling differentially affects proliferation and survival of Epstein-Barr virus-infected B cells.Entschladen, F. ; Lindquist, J.A. ; Serfling, E. ; Thiel, G. ; Kieser, A. ; Giehl, K. ; Ehrhardt, C. ; Feller, S.M. ; Ullrich, O. ; Schaper, F. ; Janssen, O. ; Hass, R. ; Friedrich, K.
Signal transduction - receptors, mediators, and genes.Petermann, S.
Funktionelle Charakterisierung der EBV-nukleären Antigene 3A und 3C (EBNA3A und EBNA3C).Ruseva, Z. ; Geiger, P.X. ; Hutzler, P. ; Kotzsch, M. ; Luber, B. ; Schmitt, M. ; Gross, E. ; Reuning, U.
Tumor suppressor KAI1 affects integrin alphavbeta3-mediated ovarian cancer cell adhesion, motility, and proliferation.Hausherr-Bohn, A.
Cellular and molecular characterisation of novel lipopeptides with anti-myeloma activities.Bergmann, C. ; Strauss, L. ; Wieckowski, E. ; Czystowska, M. ; Albers, A. ; Wang, Y. ; Zeidler, R. ; Lang, S. ; Whiteside, T.L.
Conditional immortalization of human B cells by CD40 ligation.Tumor-derived microvesicles in sera of patients with head and neck cancer and their role in tumor progression.Ruseva, Z. ; Geiger, P.X. ; Hutzler, P. ; Kotzsch, M. ; Luber, B. ; Schmitt, M. ; Gross, E. ; Reuning, U.
Tumor suppressor KAI1 affects integrin αvβ3-mediated ovarian cancer cell adhesion, motility, and proliferation.Schepers, A.
The EBV-genome comes of age: Taking advantage of an extrachromosomal virus to understand nuclear processes.Scholz, B.A. ; Heinzelmann, K. ; Kremmer, E. ; Frank, R. ; Haas, J. ; Fossum, E. ; Kempkes, B.
KSHV lytic vIRF4 (K10.1), a novel target gene of Rta and potential modulator of Rta mediated transactivation via the host CSL/CBF1 protein.Thomae, A. ; Deutsch, M. ; Papior, P. ; Hammerschmidt, W. ; Schepers, A.
Dual role of human Orc6 in origin activation.Peters, D.D. ; Lepikhov, K. ; Rodenacker, K. ; Marschall, S. ; Boersma, A. ; Hutzler, P. ; Scherb, H. ; Walter, J. ; Hrabě de Angelis, M.
Effect of IVF and laser zona dissection on DNA methylation pattern of mouse zygotes.Xing, X. ; Burgermeister, E. ; Geisler, F. ; Einwächter, H. ; Fan, L. ; Hiber, M. ; Rauser, S. ; Walch, A.K. ; Röcken, C. ; Ebeling, M. ; Wright, M.B. ; Schmid, R.M. ; Ebert, M.P.
Hematopoietically expressed homeobox is a target gene of farnesoid X receptor in chenodeoxycholic acid-induced liver hypertrophy.Sölder, E. ; Kremser, C. ; Rohr, I. ; Hutzler, P.J.S. ; Debbage, P.
Molecular mapping deep within a living human organ: Analysis of microvessel function on the timescale of seconds and with sub-micrometre spatial resolution.Sölder, E. ; Rohr, I. ; Kremser, C. ; Hutzler, P. ; Debbage, P.L.
Imaging of placental transport mechanisms: A review.Roselli, F. ; Hutzler, P. ; Wegerich, Y. ; Livrea, P. ; Almeida, O.F.
Disassembly of shank and homer synaptic clusters is driven by soluble β-amyloid₁₋₄₀ through divergent NMDAR-dependent signalling pathways.Deplazes, J. ; Fuchs, M. ; Rauser, S. ; Genth, H. ; Lengyel, E. ; Busch, R. ; Luber, B.
Rac1 and Rho contribute to the migratory and invasive phenotype associated with somatic E-cadherin mutation.Schneider, M. ; Förster, H. ; Boersma, A. ; Seiler, A. ; Wehnes, H. ; Sinowatz, F. ; Neumüller, C. ; Deutsch, M.J. ; Walch, A.K. ; Hrabě de Angelis, M. ; Wurst, W. ; Ursini, F. ; Roveri, A. ; Maleszewski, M. ; Maiorino, M. ; Conrad, M.
Mitochondrial glutathione peroxidase 4 disruption causes male infertility.Maetzel, D. ; Denzel, S. ; Mack, B. ; Canis, M. ; Went, P. ; Benk, M. ; Kieu, C. ; Papior, P. ; Baeuerle, P.A. ; Münz, M. ; Gires, O.
Nuclear signalling by tumour-associated antigen EpCAM.Herrmann, K. ; Walch, A.K. ; Balluff, B. ; Tänzer, M. ; Höfler, H. ; Krause, B.J. ; Schwaiger, M. ; Friess, H. ; Schmid, R.M. ; Ebert, M.P.
Proteomic and metabolic prediction of response to therapy in gastrointestinal cancers.Khasawneh, J. ; Schulz, M.D. ; Walch, A.K. ; Rozman, J. ; Hrabě de Angelis, M. ; Klingenspor, M. ; Buck, A. ; Schwaiger, M. ; Saur, D. ; Schmid, R.M. ; Klöppel, G. ; Sipos, B. ; Greten, F.R. ; Arkan, M.C.
Inflammation and mitochondrial fatty acid beta-oxidation link obesity to early tumor promotion.Wiech, T. ; Nikolopoulos, E. ; Weis, R. ; Langer, R. ; Bartholomé, K. ; Timmer, J. ; Walch, A.K. ; Höfler, H. ; Werner, M.
Genome-wide analysis of genetic alterations in Barrett's adenocarcinoma using single nucleotide polymorphism arrays.Reiter, R. ; Gais, P. ; Steuer-Vogt, M.K. ; Boulesteix, A.L. ; Deutschle, T. ; Hampel, R. ; Wagenpfeil, S. ; Rauser, S. ; Walch, A.K. ; Bink, K. ; Jütting, U. ; Neff, F. ; Arnold, W. ; Höfler, H. ; Pickhard, A.
Centrosome abnormalities in head and neck squamous cell carcinoma (HNSCC).Ehrhardt, A. ; Haase, R. ; Schepers, A. ; Deutsch, M.J. ; Lipps, H.J. ; Baiker, A.
Episomal vectors for gene therapy.Kieser, A.
Pursuing different 'TRADDes': TRADD signaling induced by TNF-receptor 1 and the Epstein-Barr virus oncoprotein LMP1.Norseen, J. ; Thomae, A. ; Sridharan, V. ; Aiyar, A. ; Schepers, A. ; Lieberman, P.M.
RNA-dependent recruitment of the origin recognition complex.Ying, S. ; Pettengill, M. ; Latham, E.R. ; Walch, A.K. ; Ojcius, D.M. ; Häcker, G.
Premature apoptosis of Chlamydia-infected cells disrupts chlamydial development.Schillinger, U. ; Wexel, G. ; Hacker, C. ; Kullmer, M. ; Koch, C. ; Gerg, M. ; Vogt, S. ; Ueblacker, P. ; Tischer, T. ; Hensler, D. ; Wilisch, J. ; Aigner, J. ; Walch, A.K. ; Stemberger, A. ; Plank, C.
A fibrin glue composition as carrier for nucleic acid vectors.May, F. ; Matiasek, K. ; Vroemen, M. ; Caspers, C. ; Mrva, T. ; Arndt, C. ; Schlenker, B. ; Gais, P. ; Brill, T. ; Buchner, A. ; Blesch, A. ; Hartung, R. ; Stief, C. ; Gansbacher, B. ; Weidner, N.
GDNF-transduced Schwann cell grafts enhance regeneration of erectile nerves.Riener, M.O. ; Nikolopoulos, E. ; Herr, A. ; Wild, P.J. ; Hausmann, M. ; Wiech, T. ; Orlowska-Volk, M. ; Lassmann, S. ; Walch, A.K. ; Werner, M.
Microarray comparative genomic hybridization analysis of tubular breast carcinoma shows recurrent loss of the CDH13 locus on 16q.Winkelheide, U. ; Engelhard, K. ; Kaeppel, B. ; Winkler, J. ; Hutzler, P. ; Werner, C. ; Kochs, E.
Cerebral Ischemia and Neurogenesis: A Two-time Comparison.Schmidt, R. ; Bültmann, A. ; Fischel, S. ; Gillitzer, A. ; Cullen, P. ; Walch, A.K. ; Jost, P. ; Ungerer, M. ; Tolley, N.D. ; Lindemann, S. ; Gawaz, M. ; Schömig, A. ; May, A.E.
Extracellular matrix metalloproteinase inducer (CD147) is a novel receptor on platelets, activates platelets, and augments nuclear factor kappaB-dependent inflammation in monocytes.Aubele, M. ; Walch, A.K. ; Ludyga, N. ; Braselmann, H. ; Atkinson, M.J. ; Luber, B. ; Auer, G. ; Tapio, S. ; Cooke, T. ; Bartlett, J.M.
Prognostic value of protein tyrosine kinase 6 (PTK6) for long-term survival of breast cancer patients.Zorn, J. ; Herber, M. ; Schwamberger, S. ; Adler, H. ; Kolb, H.-.
Tolerance in DLA-haploidentical canine littermates following CD6-depleted marrow transplantation and donor lymphocyte transfusion.Wiech, T. ; Nikolopoulos, E. ; Hausmann, M. ; Walch, A.K. ; Werner, M. ; Fisch, P.
A Case of Heterogeneous Breast Cancer with Clonally Expanded T-Cells in the HER2+ and Metastasis of the HER2- Tumor Cells.Walch, A.K. ; Rauser, S. ; Deininger, S.O. ; Höfler, H.
MALDI imaging mass spectrometry for direct tissue analysis: A new frontier for molecular histology.Bauer, V.L. ; Braselmann, H. ; Henke, M. ; Mattern, D. ; Walch, A.K. ; Unger, K. ; Baudis, M. ; Lassmann, S. ; Huber, R. ; Wienberg, J. ; Werner, M. ; Zitzelsberger, H.
Chromosomal changes characterize head and neck cancer with poor prognosis.Schyschka, L. ; Rudy, A. ; Jeremias, I. ; Barth, N. ; Pettit, G.R. ; Vollmar, A.M.
Spongistatin 1: A new chemosensitizing marine compound that degrades XIAP.Ehrhardt, H. ; Häcker, S. ; Wittmann, S. ; Maurer, M. ; Borkhardt, A. ; Toloczko, A. ; Debatin, K.M. ; Fulda, S. ; Jeremias, I.
Cytotoxic drug-induced, p53-mediated upregulation of caspase-8 in tumor cells.Zischka, H. ; Lichtmannegger, J. ; Jägemann, N. ; Jennen, L. ; Hamöller, D. ; Huber, E. ; Walch, A.K. ; Summer, K.H. ; Göttlicher, M.
Isolation of highly pure rat liver mitochondria with the aid of zone-electrophoresis in a free flow device (ZE-FFE).Riccio, O. ; van Gijn, M.E. ; Bezdek, A.C. ; Pellegrinet, L. ; van Es, J.H. ; Zimber-Strobl, U. ; Strobl, L.J. ; Honjo, T. ; Clevers, H. ; Radtke, F.
Loss of intestinal crypt progenitor cells owing to inactivation of both Notch1 and Notch2 is accompanied by derepression of CDK inhibitors p27Kip1 and p57Kip2.Zischka, H. ; Larochette, N. ; Hoffmann, F. ; Hamöller, D. ; Jägemann, N. ; Lichtmannegger, J. ; Jennen, L. ; Müller-Höcker, J. ; Roggel, F. ; Göttlicher, M. ; Vollmar, A.M. ; Kroemer, G.
Electrophoretic analysis of the mitochondrial outer membrane rupture induced by permeability transition.le Clorennec, C. ; Ouk, TS. ; Youlyouz-Marfak, I. ; Panteix, S. ; Martin, C.C. ; Rastelli, J. ; Adriaenssens, E. ; Zimber-Strobl, U. ; Coll, J. ; Feuillard, J. ; Jayat-Vignoles, C.
Molecular basis of cytotoxicity of Epstein-Barr virus (EBV) latent membrane protein 1 (LMP1) in EBV latency III B cells: LMP1 induces type II ligand-independent autoactivation of CD95/Fas with caspase 8-mediated apoptosis.Nakhai, H. ; Sievke, J. T. ; Klein, B. ; Mendoza-Torres, L ; Mazur, P. K. ; Algül, H. ; Radtke, F. ; Strobl, L.J. ; Zimber-Strobl, U. ; Schmid, R.M.
Conditional ablation of Notch signaling in pancreatic development.Geisler, F. ; Nagl, F. ; Mazur, P.K. ; Lee, M. ; Zimber-Strobl, U. ; Strobl, L.J. ; Radtke, F. ; Schmid, R.M. ; Siveke, J.T.
Liver-specific inactivation of Notch2, but not Notch1, compromises intrahepatic bile duct development in mice.Rothbauer, U. ; Zolghadr, K. ; Muyldermans, S. ; Schepers, A. ; Cardoso, M.C. ; Leonhardt, H.
A versatile nanotrap for biochemical and functional studies with fluorescent fusion proteins.Zychlinska, M. ; Herrmann, H. ; Zimber-Strobl, U. ; Hammerschmidt, W.
Restricted expression of Epstein-Barr virus latent genes in murine B cells derived from embryonic stem cells.Kutz, H. ; Reisbach, G. ; Schultheiss, U. ; Kieser, A.
The c-Jun N-terminal kinase pathway is critical for cell transformation by the latent membrane protein 1 of Epstein-Barr virus.Wiesner, M. ; Zentz, C. ; Mayr, C. ; Wimmer, R. ; Hammerschmidt, W. ; Zeidler, R. ; Moosmann, A.
Conditional immortalization of human B cells by CD40 ligation.Lindner, S.E. ; Zeller, K. ; Schepers, A. ; Sugden, B.
The affinity of EBNA1 for its origin of DNA synthesis is a determinant of the origin's replicative efficiency.Pich, D. ; Hummer, S. ; Spindler, M.-P. ; Schepers, A. ; Hammerschmidt, W.
Conditional gene vectors regulated in cis.Unger, K. ; Malisch, E. ; Thomas, G. ; Braselmann, H. ; Walch, A.K. ; Jackl, G. ; Lewis, P. ; Lengfelder, E. ; Bogdanova, T. ; Wienberg, J. ; Zitzelsberger, H.
Array CGH demonstrates characteristic aberration signatures in human papillary thyroid carcinomas governed by RET/PTC.Paschen, S.A. ; Christian, J.G. ; Vier, J. ; Schmidt, F. ; Walch, A.K. ; Ojcius, D.M. ; Häcker, G.
Cytopathicity of Chlamydia is largely reproduced by expression of a single chlamydial protease.Hömig-Hölzel, C. ; Hojer, C. ; Rastelli, J. ; Casola, S. ; Strobl, L.J. ; Müller, W. ; Quintanilla-Martinez, L. ; Gewies, A. ; Ruland, J. ; Rajewsky, K. ; Zimber-Strobl, U.
Constitutive CD40 signaling in B cells selectively activates the noncanonical NF-kappaB pathway and promotes lymphomagenesis.Hipp, S. ; Walch, A.K. ; Schuster, T. ; Höfler, H. ; Becker, K.-F.
Precise measurement of the E-cadherin repressor Snail in formalin-fixed endometrial carcinoma using protein lysate microarrays.Schwanbeck, R. ; Schroeder, T. ; Henning, K. ; Kohlhof, H. ; Rieber, N. ; Erfurth, M.L. ; Just, U.
Notch signaling in embryonic and adult myelopoiesis.Hense, B.A. ; Gais, P. ; Jütting, U. ; Scherb, H. ; Rodenacker, K.
Use of fluorescence information for automated phytoplankton investigation by image analysis.Unterberger, C. ; Staples, K.J. ; Smallie, T. ; Williams, L. ; Foxwell, B. ; Schaefer, A. ; Kempkes, B. ; Hofer, T.P. ; Koeppel, M. ; Lohrum, M. ; Stunnenberg, H. ; Frankenberger, M. ; Ziegler-Heitbrock, L.
Role of STAT3 in glucocorticoid-induced expression of the human IL-10 gene.Thomae, A.W. ; Pich, D. ; Brocher, J. ; Spindler, M.-P. ; Berens, C. ; Hock, R. ; Hammerschmidt, W. ; Schepers, A.
Interaction between HMGA1a and the origin recognition complex creates site-specific replication origins.Fend, F. ; Tzankov, A. ; Bink, C. ; Seidl, S. ; Quintanilla-Martinez, L. ; Kremer, M. ; Dirnhofer, S.
Modern techniques for the diagnostic evaluation of the trephine bone marrow biopsy: Methodological aspects and applications.Rastelli, J. ; Hömig-Hölzel, C. ; Seagal, J. ; Müller, W. ; Hermann, A.C. ; Rajewsky, K. ; Zimber-Strobl, U.
LMP1 signaling can replace CD40 signaling in B cells in vivo and has unique features of inducing class-switch recombination to IgG1.Matiasek, K. ; Gais, P. ; Rodenacker, K. ; Jütting, U. ; Tanck, J.J. ; Schmahl, W.
Stereological characteristics of the equine accessory nerve.Walch, A.K. ; Seidl, S. ; Hermannstädter, C. ; Rauser, S. ; Deplazes, J. ; Langer, R. ; von, Weyhern, C.H. ; Sarbia, M. ; Busch, R. ; Feith, M. ; Gillen, S. ; Höfler, H. ; Luber, B.
Combined analysis of Rac1, IQGAP1, Tiam1 and E-cadherin expression in gastric cancer.Villmann, T. ; Schleif, F.M. ; Kostrzewa, M. ; Walch, A.K. ; Hammer, B.
Classification of mass-spectrometric data in clinical proteomics using learning vector quantization methods.Bremm, A. ; Walch, A.K. ; Fuchs, M. ; Mages, J. ; Duyster, J. ; Keller, G. ; Hermannstädter, C. ; Becker, K.F. ; Rauser, S. ; Langer, R. ; von, Weyhern, C.H. ; Höfler, H. ; Luber, B.
Enhanced activation of epidermal growth factor receptor caused by tumor-derived E-cadherin mutations.Lisse, T.S. ; Thiele, F. ; Fuchs, H. ; Hans, W. ; Przemeck, G.K.H. ; Abe, K. ; Rathkolb, B. ; Quintanilla-Martinez, L. ; Hölzlwimmer, G. ; Helfrich, M. ; Wolf, E. ; Ralston, S.H. ; Hrabě de Angelis, M.
ER stress-mediated apoptosis in a new mouse model of Osteogenesis imperfecta.Bink, K. ; Haralambieva, E. ; Kremer, M. ; Ott, G. ; Beham-Schmid, C. ; de, Leval, L. ; Peh, S.C. ; Laeng, H.R. ; Jütting, U. ; Hutzler, P. ; Quintanilla-Martinez, L. ; Fend, F.
Primary extramedullary plasmacytoma: Similarities with and differences from multiple myeloma revealed by interphase cytogenetics.Slotta-Huspenina, J. ; Koch, I. ; Richter, M. ; Bink, K. ; Kremer, M. ; Specht, K. ; Krugmann, J. ; Quintanilla-Martinez, L. ; Fend, F.
Cyclin D1 positive multiple myeloma: Predominance of the short, 3'UTR-deficient transcript is associated with high cyclin D1 mRNA levels in cases with t(11;14) translocation, but does not correlate with proliferation rate or genomic deletions.Schneider, F. ; Neugebauer, J. ; Griese, J. ; Liefold, N. ; Kutz, H. ; Briseño, C. ; Kieser, A.
The viral oncoprotein LMP1 exploits TRADD for signaling by masking its apoptotic activity.Fuchs, M. ; Hermannstädter, C. ; Hutzler, P. ; Häcker, G. ; Haller, F. ; Höfler, H. ; Luber, B.
Deletion of exon 8 increases cisplatin-induced E-cadherin cleavage.Thomae, A.
Rolle des Chromatin-Proteins HMGA1a für die Definition von Replikationsursprüngen.Rastelli, J.
Latent Epstein-Barr virus infection and the germinal center reaction.Kieser, A.
Signal transduction by the Epstein-Barr virus oncogene latent membrane protein 1 (LMP1).Kieser, A.
Signal transduction by viral factors: Critical interface between the virus and ist host cell with implications for the viral life cycle and disease development.Mancao, C.
Rolle des Epstein-Barr Virus Proteins LMP2A in transformierten B-Zellen.Jandl, T.
Serologische Identifizierung und Charakterisierung von Tumorantigenen eines Neuroblastoms Stadium 3 ohne MYCN-Genamplifikatio.Hartmann, A.
Untersuchung molekularer Mechanismen der EBNA-2 vermittelten Transaktivierung.Unterberger, C.
Molekulare Mechanismen der Induktion von Interleukin-10 durch Glukokortikoide.Albermann, K. ; Lang, S. ; Zeidler, R.
Molecular profiling for the identification of new biomarkers in smokers and cancer patients.Lang, S. ; Tiwari, S. ; Andratschke, M. ; Loehr, I. ; Lauffer, L. ; Bergmann, C. ; Mack, B. ; Lebeau, A. ; Moosmann, A. ; Whiteside, T.L. ; Zeidler, R.
Immune restoration in head and neck cancer patients after in vivo COX-2 inhibition.Lang, S. ; Tiwari, S. ; Andratschke, M. ; Loehr, I. ; Lauffer, L. ; Bergmann, C. ; Mack, B. ; Lebeau, A. ; Moosmann, A. ; Whiteside, T.L. ; Zeidler, R.
Immune restoration in head and neck cancer patients after in vivo COX-2 inhibition.Bergmann, C. ; Strauss, L. ; Zeidler, R. ; Lang, S. ; Whiteside, T.L.
Expansion and characteristics of human T regulatory type 1 cells in co-cultures simulating tumor microenvironment.Bergmann, C. ; Strauss, L. ; Zeidler, R. ; Lang, S. ; Whiteside, T.L.
Expansion of human T regulatory type 1 cells in the microenvironment of cyclooxygenase 2 overexpressing head and neck squamous cell carcinoma.Wollenberg, B. ; Zeidler, R. ; Lang, S.
Kopf-Hals-Tumoren.Albert, T.K. ; Grote, K. ; Boeing, S. ; Stelzer, G. ; Schepers, A. ; Meisterernst, M.
Global distribution of negative cofactor 2 subunit-alpha on human promoters.Hausherr, A. ; Tavares, R. ; Schäffer, M. ; Obermeier, A. ; Miksch, C. ; Mitina, O. ; Ellwart, J.W. ; Hallek, M. ; Krause, G.
Inhibition of IL-6-dependent growth of myeloma cells by an acidic peptide repressing the gp130-mediated activation of Src family kinases.Tierney, R. ; Nagra, J. ; Hutchings, I. ; Shannon-Lowe, C. ; Altmann, M. ; Hammerschmidt, W. ; Rickinson, A.B. ; Bell, A.
Epstein-Barr virus exploits BSAP/Pax5 to achieve the B-cell specificity of its growth-transforming program.Zentz, C. ; Wiesner, M. ; Man, S. ; Frankenberger, B. ; Wollenberg, B. ; Hillemanns, P. ; Zeidler, R. ; Hammerschmidt, W. ; Moosmann, A.
Activated B cells mediate efficient expansion of rare antigen-specific T cells.Geisberger, R. ; Kiermayer, C. ; Hömig, C. ; Conrad, M. ; Schmidt, J. ; Zimber-Strobl, U. ; Brielmeier, M.
B- and T-cell-specific inactivation of thioredoxin reductase 2 does not impair lymphocyte development and maintenance.Mancao, C. ; Hammerschmidt, W.
Epstein-Barr virus latent membrane protein 2A is a B-cell receptor mimic and essential for B-cell survival.Popp, C.
Die Rolle der Epstein-Barr Virus nukleären Antigene 3A und 3C in der B-Zellimmortalisierung.Boccellato, F. ; Anastasiadou, E. ; Rosato, P. ; Kempkes, B. ; Frati, L. ; Faggioni, A. ; Trivedi, P.
EBNA2 Interferes with the Germinal Center Phenotype by Downregulating BCL6 and TCL1 in Non-Hodgkin's Lymphoma Cells.Besseyrias, V. ; Fiorini, E. ; Strobl, L.J. ; Zimber-Strobl, U. ; Dumortier, A. ; Koch, U. ; Arcangeli, M.-L. ; Ezine, S. ; MacDonald, H.R. ; Radtke, F.
Hierarchy of notch-delta interactions promoting T cell lineage commitment and maturation.Schouwey, K. ; Delmas, V. ; Larue,L. ; Zimber-Strobl, U. ; Strobl, L.J. ; Radtke, F. ; Beermann, F.
Notch1 and Notch2 receptors influence progressive hair graying in a dose-dependent manner.Trivedi, A.K. ; Bararia, D. ; Christopeit, M. ; Peer Zada, A.A. ; Singh, S.M. ; Kieser, A. ; Hiddemann, W. ; Behre, H.M. ; Behre, G.
Proteomic identification of C/EBP-DBD multiprotein complex: JNK1 activates stem cell regulator C/EBPalpha by inhibiting its ubiquitination.Ghosh, M. ; Kemp, M. ; Liu, G. ; Ritzi, M. ; Schepers, A. ; Leffak, M.
Differential binding of replication proteins across the human c-myc replicator.Hettich, E.
Etablierung einer optimierten Helferzelllinie zum Genvektortransfer in humane B-Zellen.Thakur, N.N.
Functional characterization of the 40 bp internal repeat of murine gamma herpesvirus-68.Andratschke, M. ; Hagedorn, H. ; Luebbers, C.W. ; Schmitt, B. ; Lang, S. ; Zeidler, R. ; Wollenberg, B.
Limited suitability of EpCAM for molecular staging of tumor borders in head and neck cancer.Hahn, U.K. ; Aichler, M. ; Boehm, R. ; Beyer, W.
Comparison of the immunological memory after DNA vaccination and protein vaccination against anthrax in sheep.Pegman, P.M. ; Smith, S.M. ; D'Souza, B.N. ; Loughran, S.T. ; Maier, S. ; Kempkes, B. ; Cahill, P.A. ; Simmons, M.J. ; Gelinas, C. ; Walls, D.
Epstein-Barr virus nuclear antigen 2 trans-activates the cellular antiapoptotic bfl-1 gene by a CBF1/RBPJk-dependent pathway.Altmann, M. ; Pich, D. ; Ruiss, R. ; Wang, J. ; Sugden, B. ; Hammerschmidt, W.
Transcriptional activation by EBV nuclear antigen 1 is essential for the expression of EBV's transforming genes.Grabusic, K. ; Maier, S. ; Hartmann, A. ; Mantik, A. ; Hammerschmidt, W. ; Kempkes, B.
The CR4 region of EBNA2 convers viability of Epstein-Barr virus-transformed B cells by CBF1-independent signalling.Gerhardt, J. ; Jafar, S. ; Spindler, M.-P. ; Ott, E. ; Schepers, A.
Identification of new human origins of DNA replication by an origin-trapping assay.Hettich, E. ; Janz, A. ; Zeidler, R. ; Pich, D. ; Hellebrand, E. ; Weissflog, B. ; Moosmann, A. ; Hammerschmidt, W.
Genetic design of an optimized packaging cell line for gene vectors transducing human B cells.Hennard, C. ; Pfuhl, T. ; Buettner, M. ; Becker, K.-H. ; Knöfel, T. ; Middeldorp, J. ; Kremmer, E. ; Niedobitek, G. ; Grässer, F.A.
The antibody 2B4 directed against the Epstein-Barr virus (EBV)-encoded nuclear antigen I (EBNA I) detects MAGE-4: Implications for studies on the EBV association of human cancers.Maier, S. ; Staffler, G. ; Hartmann, A. ; Höck, J. ; Henning, K. ; Grabusic, K. ; Mailhammer, R. ; Hoffmann, R. ; Wilmanns, M. ; Lang, R. ; Mages, J. ; Kempkes, B.
Cellular target genes of Epstein-Barr virus nuclear antigen 2.Takenaka, S. ; Karg, E.W. ; Kreyling, W.G. ; Lentner, B. ; Möller, W. ; Behnke-Semmler, M. ; Jennen, L. ; Walch, A.K. ; Michalke, B. ; Schramel, P. ; Heyder, J.
Distribution pattern of inhaled ultrafine gold particles in the rat lung.Mohan, J. ; Dement-Brown, J. ; Maier, S. ; Ise, T. ; Kempkes, B. ; Tolnay, M.
Epstein-Barr virus nuclear antigen 2 induces FcRH5 expression through CBF1.Hellebrand, E. ; Mautner, J. ; Reisbach, G. ; Nimmerjahn, F. ; Hallek, M. ; Mocikat, R. ; Hammerschmidt, W.
Epstein-Barr virus vector-mediated gene transfer into human B cells: Potential for antitumor vaccination.Altmann, M. ; Hammerschmidt, W.
Epstein-Barr Virus provides a new paradigm: A requirement for the immediate inhibition of apoptosis.Zhou, J. ; Chau, C.M. ; Deng, Z. ; Shiekhattar, R. ; Spindler, M.-P. ; Schepers, A. ; Lieberman, P.M.
Cell cycle regulation of chromatin at an origin of DNA replication.Mancao, C. ; Altmann, M. ; Jungnickel, B. ; Hammerschmidt, W.
Rescue of "crippled" germinal center B cells from apoptosis by Epstein-Barr virus.Kempkes, B. ; Strobl, L.J. ; Bornkamm, G.W. ; Zimber-Strobl, U.
EBNA-2 and Notch Signalling.Wiesner, M.
Die Diversität Cytomegalovirus-spezifischer T-Zellen nach Selektion mittels B-Zell-Vektoren.Hammer, M.H. ; Meyer, S. ; Brestrich, G. ; Moosmann, A. ; Kern, F. ; Tesfa, L. ; Babel, N. ; Mittenzweig, A. ; Rooney, C.M. ; Hammerschmidt, W. ; Volk, H.-D.
HLA type-independent generation of antigen-specific T cells for adoptive immunotherapy.Kelly, G.K. ; Milner, A.E. ; Tierney, R.J. ; Croom-Carter, D.S.G. ; Altmann, M. ; Hammerschmidt, W. ; Bell, A.I. ; Rickinson, A.B.
Epstein-barr virus nuclear antigen 2 (EBNA2) gene deletion is consistently linked with EBNA3A,-3B and -3C expression in burkitt's lymphoma cells and with increased resistance to apoptosis.Wiesner, M. ; Zentz, C. ; Hammer, M.H. ; Cobbold, M. ; Kern, F. ; Kolb, H.-J. ; Hammerschmidt, W. ; Zeidler, R. ; Moosmann, A.
Selection of CMC-specific CD8⁺ and CD4⁺ T cells by mini-EBV-transformed B cell lines.Grimm, T. ; Schneider, S. ; Naschberger, E. ; Huber, J. ; Guenzi, E. ; Kieser, A. ; Reitmeir, P. ; Schulz, T.F. ; Morris, C.A. ; Stürzl, M.
EBV latent membrane protein-1 protects B cells from apoptosis by inhibition of BAX.Maier, S. ; Santak, M. ; Mantik, A. ; Grabusic, K. ; Kremmer, E. ; Hammerschmidt, W. ; Kempkes, B.
A somatic knockout of CBF1 in a human B-cell line reveals that induction of CD21 and CCR7 by EBNA-2 is strictly CBF1 dependent and that downregulation of immunoglobulin M is partially CBF1 independent.Dudziak, D. ; Nimmerjahn, F. ; Bornkamm, G.W. ; Laux, G.
Alternative splicing generates putative soluble CD83 proteins that inhibit T cell proliferation.Pagés, F. ; Galon, J. ; Karaschuk, G. ; Dudziak, D. ; Camus, M. ; Lazar, V. ; Camilleri-Broët, S. ; Lagorce-Pagés, C. ; Lebel-Binay, S. ; Laux, G. ; Fridman, W.H.
Epstein-Barr virus nuclear antigen 2 induces interleukin-18 receptor expression in B cells.Lee, J.M. ; Lee, K.-H. ; Farrell, C.J. ; Ling, P.D. ; Kempkes, B. ; Park, J.H. ; Hayward, S.D.
EBNA2 is required for protection of latently Epstein-Barr virus-infected B cells against specific apoptotic stimuli.Hammerschmidt, W. ; Sugden, B.
Epstein-Barr virus sustains Burkitt's lymphomas and Hodgkin's disease.Lee, S.P. ; Brooks, J.M. ; Al-Jarrah, H. ; Thomas, W.A. ; Haigh, T.A. ; Taylor, G.S. ; Humme, S. ; Schepers, A. ; Hammerschmidt, W. ; Yates, J.L. ; Rickinson, A.B.
CD8 T cell recognition of endogenously expressed Epstein-Barr virus nuclear antigen 1.Feederle, R. ; Delecluse, H.J. ; Rouault, J.P. ; Schepers, A. ; Hammerschmidt, W.
Efficient somatic gene targeting in the lymphoid human cell I DG75.Gires, O. ; Pöckl, S. ; Chapman, R.D. ; Münz, M.
Targeted gene expression using a 1.1 kilobase promoter fragment of the tumour-associated antigen EpCAM.Zentz, C.
Expansion von T-Zellen seltener Spezifität mittels B-Zellen.Gires, O. ; Münz, M. ; Schaffrik, M. ; Kieu, C. ; Rauch, J. ; Ahlemann, M. ; Eberle, D. ; Mack, B. ; Wollenberg, B. ; Lang, S. ; Hofmann, T. ; Hammerschmidt, W. ; Zeidler, R.
Profile identification of disease-associated humoral antigens using AMIDA, a novel proteomics-based technology.Mautner, J. ; Pich, D. ; Nimmerjahn, F. ; Milosevic, S. ; Adhikary, D. ; Christoph, H. ; Witter, K. ; Bornkamm, G.W. ; Hammerschmidt, W. ; Behrends, U.
Epstein-Barr virus nuclear antigen 1 evades direct immune recognition by CD4+ T helper cells.Nimmerjahn, F. ; Dudziak, D. ; Dirmeier, U. ; Hobom, G. ; Riedel, A. ; Schlee, M. ; Staudt, L.M. ; Rosenwald, A. ; Behrends, U. ; Bornkamm, G.W. ; Mautner, J.
Active NF-kB signalling is a prerequisite for influenza virus infection.Schlee, M. ; Krug, T. ; Gires, O. ; Zeidler, R. ; Hammerschmidt, W. ; Mailhammer, R. ; Laux, G. ; Sauer, G. ; Lovric, J. ; Bornkamm, G.W.
Identification of Epstein-Barr virus (EBV) nuclear antigen 2 (EBNA2) target proteins by proteome analysis: Activation of EBNA2 in conditionally immortalized B cells reflects early events after infection of primary b cells by EBV.Ruvolo, V. ; Sun, L. ; Howard, K. ; Sung, S. ; Delecluse, H.-J. ; Hammerschmidt, W. ; Swaminathan, S.
Functional analysis of Epstein-Barr virus SM protein: Identification of amino acids essential for structure, transactivation, splicing inhibition and virion production.Schlee, M.
Identifizierung und Charakterisierung von Zielgenen des EBV nuklearen antigens 2 (EBNA2).Schlee, M.
Identifizierung und Charakterisierung von Zielgenen des Epstein-Barr Virus nukleären Antigens 2 (EBNA2).Lang, S. ; Zeidler, R.
Immune restoration in head and neck cancer patients via cyclooxygenase inhibition: An update.Lang, S. ; Lauffer, L. ; Clausen, C. ; Löhr, I. ; Schmitt, B. ; Hölzel, D. ; Wollenberg, B. ; Gires, O. ; Kastenbauer, E. ; Zeidler, R.
Impaired monocyte function in cancer patients: restoration with a cyclooxygenase-2 inhibitor.Zeidler, R. ; Meyer, A. ; Gires, O. ; Schmitt, B. ; Mack, B. ; Lindhofer, H. ; Wollenberg, B. ; Walz, A.
TNFalpha contributes to the antitumor activity of a bispecific, trifunctional antibody.Gires, O. ; Kieu, C. ; Fix, P. ; Schmitt, B. ; Münz, M. ; Wollenberg, B. ; Zeidler, R.
Tumor necrosis factor alpha negatively regulates the expression of the carcinoma-associated antigen epithelial cell adhesion molecule.Lang, S. ; Zeidler, R. ; Pauli, C. ; Andratschke, M. ; Wollenberg, B.
IL-2 Gentherapie bei HNO-Karzinomen.Zeidler, R. ; Csanady, M. ; Gires, O. ; Lang, S. ; Schmitt, B. ; Wollenberg, B.
Tumor cell-derived prostaglandin E2 inhibits monocyte function by interfering with CCR5 and Mac-1.Chaubal, S. ; Wollenberg, B. ; Kastenbauer, E. ; Zeidler, R.
Ep-CAM - a marker for the detection of disseminated tumor cells in patients suffering from SCCHN.Wollenberg, B. ; Kastenbauer, P. ; Mundl, H. ; Schaumberg, J. ; Meyer, A. ; Andratschke, M. ; Lang, S. ; Pauli, C. ; Zeidler, R. ; Ihrler, S. ; Löhrs, U. ; Naujoks, K. ; Rollston, R.
Gene therapy--phase I trial for primary untreated head and neck squamous cell cancer (HNSCC) UICC stage II-IV with a single intratumoral injection of hIL-2 plasmids formulated in DOTMA/Chol.Lang, S. ; Whiteside, T.L. ; Lebeau, A. ; Zeidler, R. ; Mack, B. ; Wollenberg, B.
Impairment of T-cell activation in head and neck cancer in situ and in vitro: strategies for an immune restoration.Lang, S. ; Zeidler, R. ; Meyer, A. ; Reiman, V. ; Wollenberg, B. ; Kastenbauer, E.
Targeting head and neck cancer by GM-CSF-mediated gene therapy in vitro.Wollenberg, B. ; Lang, S. ; Friess, T. ; Naujoks, K. ; Meyer, A. ; Kastenbauer, E. ; Zeidler, R.
Induktion einer antitumoralen Immunantwort im Mausmodell nach Vakzinierung mit B7.1 exprimierenden Tumorzellen.Falk, M.H. ; Meier, T. ; Issels, R.D. ; Brielmeier, M. ; Scheffer, B. ; Bornkamm, G.W.
Apoptosis in burkitt lymphoma cells is prevented by promotion of cysteine uptake.Wollenberg, B. ; Zeidler, R. ; Lebeau, A. ; Mack, B. ; Lang, S.
Lack of B7.1 and B7.2 on head and neck cancer cells and possible significance for gene therapy.Wollenberg, B. ; Lang, S. ; Schmitt, B. ; Kastenbauer, E. ; Zeidler, R.
In vitro studies of liposome-mediated gene transfer into head and neck cancer cell lines.Wollenberg, B. ; Schmidt, W. ; Schmitt, B. ; Lang, S. ; Zeidler, R.
Rezeptor-mediierter Gentransfer in Plattenepithelkarzinome des Kopf-Hals-Bereiches.Weissinger, E.M. ; Thalmeier, K. ; Düll, T. ; Grammer, C. ; Kempkes, B. ; Brielmeier, M. ; Schumm, M. ; Kolb, H.-J.
Mosaicism of bcr/abl protein expression in B-cells in CML.Bornkamm, G.W. ; Delecluse, H.-J. ; Hammerschmidt, W. ; Bullerdiek, J.
Episomal and Integrated Copies of Epstein-Barr Virus Coexist in Burkitt Lymphoma Cell Lines.Reisbach, G. ; Bartke, I. ; Kempkes, B. ; Kostka, G. ; Ellwart, J. ; Birner, A. ; Thalmeier, K. ; Mailhammer, R. ; Bornkamm, G.W. ; Ullrich, A. ; Dörmer, P.
Characterization of Hemopoietic Cell Populations from Human Cord Blood Expressing c-kit.Zimber-Strobl, U. ; Kremmer, E. ; Grässer, F. ; Laux, G. ; Bornkamm, G.W.
The Epstein-Barr Nuclear Antigen 2 (EBNA2) Transactivates the Terminal Protein 1 Gene by Interacting with a Cis-Element Located in the Promoter Region.Schepers, A. ; Pich, D. ; Mankertz, J. ; Hammerschmidt, W.
Cis-acting Elements in the Lytic Origin of DNA Replication of Epstein-Barr Virus.Delecluse, H.-J. ; Bornkamm, G.W. ; Hammerschmidt, W.
Integration of EBV and MDV in B- and T-cell Lymphomas.Laux, G. ; Dugrillon, F. ; Eckert, C. ; Zimber-Strobl, U. ; Bornkamm, G.W.
Delineation of the Cis-Acting Sequence Mediating Transactivation of a bi-Directional Latent Promoter Region by Epstein-Barr Virus Nuclear Antigen 2 (EBNA2).Kempkes, B. ; Pawlita, M. ; Oppenländer, M. ; Rottenberger, C. ; Kremmer, E. ; Bornkamm, G.W.
Expression of EBNA2 as a Conditional Mutant.Cordier-Bussat, M. ; Calender, A. ; Vuillaume, M. ; Bornkamm, G.W. ; Lenoir, G.M.
Expression of the Epstein-Barr Virus (EBV) Latent Membrane Protein is Tightly regulated, Independently of EB Nuclear Antigen 2 and of EBV Integration or Copy Number.Falk, M.H. ; Scheffer, B. ; Bornkamm, G.W.
Irradiated Human Fibroblasts Substitute for Epstein-Barr Virus in Stimulating the Clonogenicity of Burkitt Lymphoma Cells.Schepers, A. ; Pich, D. ; Hammerschmidt, W.
A transcription factor with homology to the AP-1 family links RNA transcription and DNA replication in the lytic cycle of Epstein-Barr virus.Kohlhuber, F. ; Strobl, L.J. ; Eick, D.
Early down-regulation of c-myc in dimethylsulfoxide-induced mouse erythroleukemia (MEL) cells is mediated at the P1/P2 promoters.Reisbach, G. ; Bartke, I. ; Kempkes, B. ; Kostka, G. ; Ellwart, J.W. ; Birner, A. ; Thalmeier, K. ; Mailhammer, R. ; Bornkamm, G.W. ; Ullrich, A. ; Dörmér, P.G.
Characterization of hemopoietic cell populations from human cord blood expressing c-kit.Delecluse, H.J. ; Schüller, S. ; Hammerschmidt, W.
Latent Marek's disease virus can be activated from its chromosomally integrated state in herpesvirus-transformed lymphoma cells.Hammerschmidt, W. ; Mankertz, J.
Herpesviral DNA replication: between the known and unknown.Zimber-Strobl, U. ; Suentzenich, K.O. ; Falk, M. ; Laux, G. ; Cordier, M.P. ; Calender, A. ; Billaud, M. ; Lenoir, G.M. ; Bornkamm, G.W.
Epstein-Barr virus terminal protein gene transcription is dependent on EBNA2 expression and provides evidence for viral integration into the host genome.