Publications Julia Hess
Zurück2022 Wissenschaftlicher Artikel in Molecular Cancer Mol. Cancer 21:178 (2022)
A transcriptomic map of EGFR-induced epithelial-to-mesenchymal transition identifies prognostic and therapeutic targets for head and neck cancer.
2022 Wissenschaftlicher Artikel in Journal of Oral Pathology and Medicine J. Oral Pathol. Med. 51, 738-746 (2022)
Analysis of genetic variants of frequently mutated genes in human papillomavirus-negative primary head and neck squamous cell carcinoma, resection margins, local recurrences and corresponding circulating cell-free DNA.
2022 Wissenschaftlicher Artikel in European Journal of Cancer Eur. J. Cancer 176, 41-49 (2022)
DeepClassPathway: Molecular pathway aware classification using explainable deep learning.
2022 Wissenschaftlicher Artikel in Cancers Cancers 14:3745 (2022)
Integration of p16/HPV DNA status with a 24-miRNA-defined molecular phenotype improves clinically relevant stratification of head and neck cancer patients.
2022 Wissenschaftlicher Artikel in Laboratory Investigation Lab. Invest. 102, 1400-1405 (2022)
Simultaneous metabolite MALDI-MSI, whole exome and transcriptome analysis from formalin-fixed paraffin-embedded tissue sections.
2022 Wissenschaftlicher Artikel in Frontiers in Oncology Front. Oncol. 12:878675 (2022)
IL1 pathway in HPV-negative HNSCC cells is an indicator of radioresistance after photon and carbon ion irradiation without functional involvement.
2022 Wissenschaftlicher Artikel in Radiation Oncology Radiat. Oncol. 17:79 (2022)
Integrative analysis of therapy resistance and transcriptomic profiling data in glioblastoma cells identifies sensitization vulnerabilities for combined modality radiochemotherapy.
2022 Wissenschaftlicher Artikel in Clinical and translational radiation oncology Clin. Transl. Radiat. Oncol. 34, 51-56 (2022)
Biopsy-derived oral keratinocytes – A model to potentially test for oral mucosa radiation sensitivity.
2022 Wissenschaftlicher Artikel in Clinical Cancer Research Clin. Cancer Res. 28, 1038-1052 (2022)
Therapy-related transcriptional subtypes in matched primary and recurrent head and neck cancer.
2022 Wissenschaftlicher Artikel in Cancer Biomarkers Cancer Biomark. 33, 331-347 (2022)
MicroRNA-182-5p and microRNA-205-5p as potential biomarkers for prognostic stratification of p16-positive oropharyngeal squamous cell carcinoma.
2021 Wissenschaftlicher Artikel in Cell Death & Disease Cell Death Dis. 12:1162 (2021)
Early senescence and production of senescence-associated cytokines are major determinants of radioresistance in head-and-neck squamous cell carcinoma.
2021 Wissenschaftlicher Artikel in International Journal of Cancer Int. J. Cancer, DOI: 10.1002/ijc.33842 (2021)
Tumor DNA-methylome derived epigenetic fingerprint identifies HPV-negative head and neck patients at risk for locoregional recurrence after postoperative radiochemotherapy.
2021 Wissenschaftlicher Artikel in Head and Neck Head Neck 43, 3707-3719 (2021)
Human microRNA-182-5p and kinectin 1: Potential biomarkers for prognosis in oral squamous cell carcinoma.
2021 Strahlentherapie und Onkologie : Journal of Radiation Oncology, Biology, Physics Strahlenther. Onkol., DOI: 10.1007/s00066-021-01869-z (2021)
Correction to: Innovative radiation oncology Together-Precise, Personalized, Human.
2021 Wissenschaftlicher Artikel in Strahlentherapie und Onkologie : Journal of Radiation Oncology, Biology, Physics Strahlenther. Onkol., DOI: 10.1007/s00066-021-01843-9 (2021)
Innovative radiation oncology Together – Precise, Personalized, Human: Vision 2030 for radiotherapy & radiation oncology in Germany.
2021 Wissenschaftlicher Artikel in International Journal of Molecular Sciences Int. J. Mol. Sci. 22:7064 (2021)
Metformin protects against radiation-induced acute effects by limiting senescence of bronchial-epithelial cells.
2021 Wissenschaftlicher Artikel in EMBO Molecular Medicine EMBO Mol. Med.:e14323 (2021)
Very-low-carbohydrate diet enhances human T-cell immunity through immunometabolic reprogramming.
2021 Wissenschaftlicher Artikel in EMBO Reports EMBO Rep. 22:e49568 (2021)
Interferon-induced degradation of the persistent hepatitis B virus cccDNA form depends on ISG20.
2021 Wissenschaftlicher Artikel in Frontiers in Oncology Front. Oncol. 11:612354 (2021)
Inhibition of HSP90 as a strategy to radiosensitize glioblastoma: Targeting the DNA damage response and beyond.
2021 Wissenschaftlicher Artikel in Stem Cell Reports Stem Cell Rep. 16, 913-925 (2021)
Generation and differentiation of adult tissue-derived human thyroid organoids.
2021 Wissenschaftlicher Artikel in Molecular Oncology Mol. Oncol. 15, 1040-1053 (2021)
Digital scoring of EpCAM and slug expression as prognostic markers in head and neck squamous cell carcinomas.
2020 Meeting abstract in Strahlentherapie und Onkologie : Journal of Radiation Oncology, Biology, Physics Strahlenther. Onkol. 196, 1, S119-S120 (2020)
Risk Stratification of Glioblastoma Patients using Blood Plasma Samples.
2020 Meeting abstract in Strahlentherapie und Onkologie : Journal of Radiation Oncology, Biology, Physics Strahlenther. Onkol. 196, 1, S158-S159 (2020)
DNA copy number and DNA methylome analysis of primary prostate cancer and pathologic lymph node metastases in patients with low and high Gleason score.
2020 Meeting abstract in Strahlentherapie und Onkologie : Journal of Radiation Oncology, Biology, Physics Strahlenther. Onkol. 196, 1, S184-S184 (2020)
Radiation-induced senescence as potential target for normal tissue protection.
2020 Meeting abstract in Strahlentherapie und Onkologie : Journal of Radiation Oncology, Biology, Physics Strahlenther. Onkol. 196, 1, S189-S190 (2020)
Intrinsic radioresistance and intra-tumoral heterogeneity in HNSCC.
2020 Meeting abstract in Strahlentherapie und Onkologie : Journal of Radiation Oncology, Biology, Physics Strahlenther. Onkol. 196, 1, S49-S50 (2020)
Patient-derived HNSCC cell lines and subclones reflect inter- and intra-tumoral heterogeneity regarding various molecular and phenotypic aspects.
2020 Wissenschaftlicher Artikel in Neuro-oncology advances Neurooncol. Adv. 2:vdaa137 (2020)
Improved risk stratification in younger IDH wild-type glioblastoma patients by combining a 4-miRNA signature with MGMT promoter methylation status.
2020 Wissenschaftlicher Artikel in Radiation Oncology Radiat. Oncol. 15:182 (2020)
Transcriptome network of the papillary thyroid carcinoma radiation marker CLIP2.
2020 Wissenschaftlicher Artikel in Radiation Oncology Radiat. Oncol. 15:109 (2020)
Single-center versus multi-center data sets for molecular prognostic modeling: A simulation study.
2020 Wissenschaftlicher Artikel in Radiation Oncology Radiat. Oncol. 15:7 (2020)
Definitive chemoradiotherapy in patients with squamous cell cancers of the head and neck-results from an unselected cohort of the clinical cooperation group "Personalized Radiotherapy in Head and Neck Cancer".
2020Vortrag: ESTRO 2020, 03-07 April 2020, Wien. (2020)
4-miRNA signature and MGMT promoter methylation improve risk stratisfaction in glioblastoma.
2020 Wissenschaftlicher Artikel in Cellular and Molecular Life Sciences - CMLS Cell. Mol. Life Sci. 77, 3401–3422 (2020)
Direct conversion of human fibroblasts into therapeutically active vascular wall-typical mesenchymal stem cells.
2019 Wissenschaftlicher Artikel in Head and Neck Head Neck 41, 3499-3515 (2019)
MicroRNA expression patterns in oral squamous cell carcinoma: Hsa-mir-99b-3p and hsa-mir-100-5p as novel prognostic markers for oral cancer.
2019 Meeting abstract in Strahlentherapie und Onkologie : Journal of Radiation Oncology, Biology, Physics Strahlenther. Onkol. 195, S63-S63 (2019)
Validation of a 4-miRNA prognosticator allowing for improved risk stratification of glioblastoma patients in combination with MGMT promoter methylation status.
2019 Meeting abstract in Strahlentherapie und Onkologie : Journal of Radiation Oncology, Biology, Physics Strahlenther. Onkol. 195, S76-S76 (2019)
Inherent resistance of head and neck tumors: Cellular senescence and associated cyokine production as key mechanisms in vitro and in vivo.
2019 Meeting abstract in Strahlentherapie und Onkologie : Journal of Radiation Oncology, Biology, Physics Strahlenther. Onkol. 195, S75-S76 (2019)
Patient-derived HNSCC cell lines and subclones reflect inter- and intra-tumoral heterogeneity regarding genomic copy number alterations and radiation response.
2019 Meeting abstract in Strahlentherapie und Onkologie : Journal of Radiation Oncology, Biology, Physics Strahlenther. Onkol. 195, S24-S25 (2019)
A 16q24.3 4-gene mRNA signature predicts outcome in radio(chemo)therapy-treated head and neck squamous cell carcinoma.
2019 Meeting abstract in Strahlentherapie und Onkologie : Journal of Radiation Oncology, Biology, Physics Strahlenther. Onkol. 195, S176-S176 (2019)
Evaluation of CD44v6 targeting strategies in HNSCC.
2019 Meeting abstract in Strahlentherapie und Onkologie : Journal of Radiation Oncology, Biology, Physics Strahlenther. Onkol. 195, S63-S64 (2019)
In-vitro and in-vivo characterization of a glioblastoma cell line panel.
2019 Meeting abstract in Strahlentherapie und Onkologie : Journal of Radiation Oncology, Biology, Physics Strahlenther. Onkol. 195, S25-S25 (2019)
A five-microRNA-signature predicts recurrence and survival in HPV-negative HNSCC.
2019 Wissenschaftlicher Artikel in Nature Communications Nat. Commun. 10:1415 (2019)
PiggyBac transposon tools for recessive screening identify B-cell lymphoma drivers in mice.
2019 Wissenschaftlicher Artikel in Clinical Cancer Research Clin. Cancer Res. 25, 1505-1516 (2019)
A five-microRNA signature predicts survival and disease control of patients with head and neck cancer negative for HPV-infection.
2018 Meeting abstract in Cancer Research Cancer Res. 78 (2018)
Evolutionary trajectories and KRAS gene dosage define pancreatic cancer phenotypes.
2018 Wissenschaftlicher Artikel in Scientific Reports Sci. Rep. 8:14582 (2018)
High expression of EpCAM and Sox2 is a positive prognosticator of clinical outcome for head and neck carcinoma.
2018 Wissenschaftlicher Artikel in PLoS Biology PLoS Biol. 16:e2006624 (2018)
EpCAM ectodomain EpEX is a ligand of EGFR that counteracts EGF-mediated epithelial-mesenchymal transition through modulation of phospho-ERK1/2 in head and neck cancers.
2018 Wissenschaftlicher Artikel in Molecular Oncology Mol. Oncol., DOI: 10.1002/1878-0261.12388 (2018)
A prognostic mRNA expression signature of four 16q24.3 genes in radio(chemo)therapy-treated head and neck squamous cell carcinoma (HNSCC).
2018 Meeting abstract in Radiotherapy and Oncology Radiother. Oncol. 127, S1266-S1267 (2018)
HNSCC derived cell lines and subclones differ in genomic copy number changes and radiation response.
2018 Meeting abstract in Radiotherapy and Oncology Radiother. Oncol. 127, S251-S251 (2018)
Prognostic biomarkers and targets for personalization of radiotherapy of HNSCC: CD44v6.
2018 Wissenschaftlicher Artikel in Radiation Oncology Radiat. Oncol. 13:123 (2018)
Postoperative (chemo) radiation in patients with squamous cell cancers of the head and neck - clinical results from the cohort of the clinical cooperation group "Personalized Radiotherapy in Head and Neck Cancer".
2018 Wissenschaftlicher Artikel in International Journal of Cancer Int. J. Cancer 143, 1505-1515 (2018)
A genomic copy number signature predicts radiation exposure in post-Chernobyl breast cancer.
2018 Wissenschaftlicher Artikel in Nature Nature 554, 62-68 (2018)
Evolutionary routes and KRAS dosage define pancreatic cancer phenotypes.
2018 Wissenschaftlicher Artikel in International Journal of Cancer Int. J. Cancer 142, 573-583 (2018)
Expression of miRNA-26b-5p and its target TRPS1 is associated with radiation exposure in post-Chernobyl breast cancer.
2017 Meeting abstract in Strahlentherapie und Onkologie : Journal of Radiation Oncology, Biology, Physics Strahlenther. Onkol. 193, S147-S148 (2017)
The influence of anemia, nicotine abuse and co-morbidities in patients with adjuvant radio(chemo)therapy in HNSCC.
2017 Meeting abstract in Strahlentherapie und Onkologie : Journal of Radiation Oncology, Biology, Physics Strahlenther. Onkol. 193, S154-S154 (2017)
In-vitro and in-vivo characterization of a glioblastoma cell line panel.
2017 Meeting abstract in Strahlentherapie und Onkologie : Journal of Radiation Oncology, Biology, Physics Strahlenther. Onkol. 193, S85-S85 (2017)
Increased CD44v6 expression confers radioresistance in subsets of HNSCC.
2017 Meeting abstract in Strahlentherapie und Onkologie : Journal of Radiation Oncology, Biology, Physics Strahlenther. Onkol. 193, S84-S84 (2017)
Irradiated HPV+ head and neck cancer cells induce an interferon related gene expression in various innate immune cell subtypes.
2017 Meeting abstract in Strahlentherapie und Onkologie : Journal of Radiation Oncology, Biology, Physics Strahlenther. Onkol. 193, S149-S149 (2017)
Subgroups of HPV-positive and HPV-negative head and neck squamous cell carcinoma differing in global copy number changes and prognosis.
2017 Wissenschaftlicher Artikel in Stem Cell Reports Stem Cell Rep. 8, 919-932 (2017)
In vitro generation of vascular wall-resident multipotent stem cells of mesenchymal nature from murine induced pluripotent stem cells.
2017 Wissenschaftlicher Artikel in Frontiers in Bioscience Front. Biosci. 22, 348-369 (2017)
Interconnection between DNA damage, senescence, inflammation, and cancer.
2017 Review in Mutation Research / Reviews in Mutation Research Mutat. Res.- Rev. Mutat. Res. 771, 59-84 (2017)
Ionizing radiation biomarkers in epidemiological studies – An update.
2017 Wissenschaftlicher Artikel in Cancer Letters Cancer Lett. 386, 87-99 (2017)
Genomic amplification of Fanconi anemia complementation group A (FancA) in head and neck squamous cell carcinoma (HNSCC): Cellular mechanisms of radioresistance and clinical relevance.
2016 Wissenschaftlicher Artikel in PLoS ONE PLoS ONE 11:e0160791 (2016)
Natural cubic spline regression modeling followed by dynamic network reconstruction for the identification of radiation-sensitivity gene association networks from time-course transcriptome data.
2016 Wissenschaftlicher Artikel in Radiation Oncology Radiat. Oncol. 11:94 (2016)
Transcriptomic analyses of the radiation response in head and neck squamous cell carcinoma subclones with different radiation sensitivity: Time-course gene expression profiles and gene association networks.
2016 Editorial in Clinical Oncology Clin. Oncol. 28, 619-621 (2016)
Established and emerging biomarkers of radiation exposure.
2015 Wissenschaftlicher Artikel in International Journal of Molecular Sciences Int. J. Mol. Sci. 16, 30204-30222 (2015)
MicroRNA-target network inference and local network enrichment analysis identify two microRNA clusters with distinct functions in head and neck squamous cell carcinoma.
2015 Meeting abstract in Strahlentherapie und Onkologie : Journal of Radiation Oncology, Biology, Physics Strahlenther. Onkol. 191, S77 (2015)
Signalling networks associated with FancA mediated radioresistance in cells of head and neck squamous cell carcinoma.
2015 Meeting abstract in Strahlentherapie und Onkologie : Journal of Radiation Oncology, Biology, Physics Strahlenther. Onkol. 191, S90 (2015)
The influence of FancA overexpression on radioresistance in oral keratinocytes and HNSCC cells.
2015 Meeting abstract in Strahlentherapie und Onkologie : Journal of Radiation Oncology, Biology, Physics Strahlenther. Onkol. 191, S121 (2015)
Inherent radioresistance of head and neck squamous cell carcinoma cells: Principal component analysis identifies cellular senescence as a crucial driver.
2015 Meeting abstract in Strahlentherapie und Onkologie : Journal of Radiation Oncology, Biology, Physics Strahlenther. Onkol. 191, S86-S87 (2015)
Identification and validation of predictive markers in head and neck squamous cell carcinomas.
2015 Wissenschaftlicher Artikel in Radiation Oncology Radiat. Oncol. 10:223 (2015)
CFAssay: Statistical analysis of the colony formation assay.
2015 Meeting abstract in European Journal of Cancer Eur. J. Cancer 51, S121 (2015)
Fanconi anemia, complementation group A (FancA) overexpression confers radioresistance to oral keratinocytes.
2015 Wissenschaftlicher Artikel in BMC Genomics BMC Genomics 16:654 (2015)
Integrative analysis of the microRNA-mRNA response to radiochemotherapy in primary head and neck squamous cell carcinoma cells.
2015 Wissenschaftlicher Artikel in Carcinogenesis Carcinogenesis 36, 1381-1387 (2015)
Genomic copy number analysis of Chernobyl papillary thyroid carcinoma in the Ukrainian-American Cohort.
2015 Wissenschaftlicher Artikel in Clinical Cancer Research Clin. Cancer Res. 21, 4440-4450 (2015)
Model matters: Differences in orthotopic rat hepatocellular carcinoma physiology determine therapy response to sorafenib.
2015 Wissenschaftlicher Artikel in Carcinogenesis Carcinogenesis 36, 748-756 (2015)
Dose-dependent expression of CLIP2 in post-Chernobyl papillary thyroid carcinomas.
2015 Radiation Oncology Radiat. Oncol. 10:102 (2015)
Erratum: Changes in circulating microRNAs after radiochemotherapy in head and neck cancer patients.
2015 Wissenschaftlicher Artikel in British Journal of Haematology Br. J. Haematol. 169, 90-102 (2015)
Immunotherapy with the trifunctional anti-CD20 x anti-CD3 antibody FBTA05 (Lymphomun) in paediatric high-risk patients with recurrent CD20-positive B cell malignancies.
2015 Wissenschaftlicher Artikel in Oncogene Oncogene 34, 3917-3925 (2015)
CLIP2 as radiation biomarker in papillary thyroid carcinoma.
2014 Meeting abstract in European Journal of Cancer Eur. J. Cancer 50, S229 (2014)
FancA overexpression confers radioresistance to cells of head and neck squamous cell carcinoma.
2014 Meeting abstract in European Journal of Cancer Eur. J. Cancer 50, S229 (2014)
Comparative global characterisation of microRNA-expression in radiation-associated and sporadic breast carcinomas.
2014 Meeting abstract in European Journal of Cancer Eur. J. Cancer 50, S113 (2014)
CLIP2 as radiation biomarker in papillary thyroid carcinoma.
2014 Meeting abstract in Strahlentherapie und Onkologie : Journal of Radiation Oncology, Biology, Physics Strahlenther. Onkol. 190, 29 (2014)
FANCA overexpression confers radioresistance to cells of head and neck squamous cell carcinoma.
2013 Wissenschaftlicher Artikel in Radiation Oncology Radiat. Oncol. 8:296 (2013)
Changes in circulating microRNAs after radiochemotherapy in head and neck cancer patients.
2013 Wissenschaftlicher Artikel in Journal of Translational Medicine J. Transl. Med. 11:160 (2013)
Immunotherapy with FBTA05 (Bi20), a trifunctional bispecific anti-CD3 x anti-CD20 antibody and donor lymphocyte infusion (DLI) in relapsed or refractory B-cell lymphoma after allogeneic stem cell transplantation: Study protocol of an investigator-driven, open-label, non-randomized, uncontrolled, dose-escalating phase I/II-trial.
München, Ludwig-Maximilians-Universität, Fakultät für Biologie, Diss., 2012, 248 S.
Molekulargenetische Veränderungen auf Chromosom 7q11 als strahlenspezifische Marker in papillären Schilddrüsenkarzinomen nach dem Reaktorunfall von Tschernobyl.
2012 Wissenschaftlicher Artikel in Journal of Translational Medicine J. Transl. Med. 10:219 (2012)
Ganglioside GD2-specific trifunctional surrogate antibody Surek demonstrates therapeutic activity in a mouse melanoma model.
2012 Wissenschaftlicher Artikel in Endocrine-Related Cancer Endocr. Relat. Cancer 19, 409-421 (2012)