Dr. Theodoros Kapellos
Junior group leader, Institute for Lung Health and Immunity"My group studies how immune cells contribute to the progression of obstructive airway diseases. We aim to identify druggable molecular pathways that ameliorate inflammatory responses and promote tissue regeneration."
"My group studies how immune cells contribute to the progression of obstructive airway diseases. We aim to identify druggable molecular pathways that ameliorate inflammatory responses and promote tissue regeneration."
Academic career and research areas
Dr. Kapellos obtained his bachelor’s degree in biology from the Aristotle University of Thessaloniki in Greece with an orientation in molecular biology, genomics and genetics. In 2010, he moved to the United Kingdom and Imperial College London to be trained as an immunologist from where he graduated with Distinction.
One year later he began his DPhil studies at the University of Oxford and the Sir William Dunn School of Pathology where he studied the effects of lipophilic chemical compounds called cannabinoids on innate immune cell functions under inflammatory conditions using in vitro functional assays and in vivo models of disease. During his work, Dr. Kapellos discovered the anti-inflammatory role of cannabinoids which mediates through the regulation of neutrophil chemotaxis. His next stop was the University of Bonn in Germany where he conducted his postdoctoral work under the supervision of Prof. Joachim L. Schultze. He undertook pioneering research characterizing the myeloid cell compartment in the bronchoalveolar space and peripheral blood of patients with chronic obstructive pulmonary disease (COPD). Furthermore, he collaborated with Prof. Christine S. Falk, a leader in transplantation immunology, as well as the pharmaceutical company AstraZeneca on projects that compared the role of myeloid cells in the development of end-state lung diseases, such as emphysema, pulmonary fibrosis, pulmonary arterial hypertension and lung cancer. At Helmholtz Zentrum München, Dr. Kapellos extends his work on the discovery of novel immunoregulatory pathways that can be harnessed to ameliorate tissue damage and promote epithelial regeneration in obstructive airway diseases, including COPD, bronchiectasis and asthma.
Skills
Asthma Bioinformatics Immunology Respiratory Medicine Non-cystic Fibrosis Myeloid Cells Bronchiectasis COPD
Professional Background
Junior group leader at the Institute of Lung Health and Immunity, Helmholtz Munich
Senior scientist at the Institute of Lung Health and Immunity, Helmholtz Munich
Postdoctoral scientist at the University of Bonn, Germany
DPhil in Pathology at the University of Oxford, United Kingdom
Honors and Awards
2023 - ERS short-term Fellowship
2022 - ERS Geoffrey Laurent Award
2017 – Full fellow of the Higher Education Academy of the UK
2016 - MRC Supplementary Fund