Principal Investigator Helmholtz Pioneer Campus
Dr. Celia Martinez-Jimenez
Research Area
Throughout my scientific career I have focused my studies on mechanisms of gene regulation. In Spain, I was awarded with a predoctoral fellowship and two grants for short stays abroad. I obtained a European PhD, acknowledged with a National PhD Award. I performed two postdoctoral stays funded by a Marie Curie Program and FEBS long-term fellowship respectively, expanding my knowledge to in vivo models. In 2015, I was funded by the Wellcome trust Sanger Institute and I was seconded in the University of Cambridge. At present, I am a principal investigator in the Helmholtz Pioneer Campus (Helmholtz Zentrum München, Munich, Germany)
Complementarily, I studied a Master in Business Administration (and I obtained the 1stCEU Entrepreneurship Award) being able to understand the priorities of the private sector and develop high-quality translational research. During three years, I was working as Business Development Manager in a spin-off. Additionally, I have experience as an assistant professor in the University for five academic years along with experience in mentoring students.
Professional Background
Principal Investigator Helmholtz Pioneer Campus, Helmholtz Zentrum München
Post-doctoral Fellow (3rd) University of Cambridge / CRUK CI / Sanger Institute (UK)
Business Development Manager Applicacell Biotech, S. L. (Spin-off, ES)
European Ph.D. in Biochemistry. University of Valencia (Spain)
Honors and Awards
- Inaugural Janet Thornton Fellow 2015
- Postdoctoral Long-Term FEBS fellowship by Federation of European Biochemical Societies (FEBS) 2010
- National PhD Award by the University of Valencia (ES) 2007
- Marie Curie postdoctoral fellowship (ITN)2015 2006
Publications
Makris, K. ; Fonda, V. ; Ramadhani, F.F. ; Fadel, L. ; Davezac, M. ; Payet, B. ; Deligiannis, I.K. ; Zhang, L. ; Horn, T. ; Heimerl, L. ; Jouffe, C. ; Heddes, M. ; Martinez Jimenez, C.P. ; Quagliarini, F. ; Uhlenhaut, N.H.
Hepatic metabolic reprogramming in male mice during short-term caloric restriction involves enhanced glucocorticoid rhythms.Neckermann, L. ; Erdösi, P. ; Zhang, L. ; Assum, I. ; Dropmann, A. ; Alaoua, S. ; Büttner, M. ; Lin, T. ; Gerstner, M. ; Ebert, M.P. ; Bantel, H. ; Dooley, S. ; Kluth, A. ; Menden, M.P. ; Martinez Jimenez, C.P. ; Hammad, S.
Preclinical evaluation of human ABCB5+ skin-derived stem cells reveals regenerative mechanisms and prognostic markers in a novel ACLF mouse model.Yin, K. ; Büttner, M. ; Deligiannis, I.K. ; Strzelecki, M. ; Zhang, L. ; Talavera Lopez, C.N. ; Theis, F.J. ; Odom, D.T. ; Martinez Jimenez, C.P.
Polyploidisation pleiotropically buffers ageing in hepatocytes.Sánchez Quant, E.S. ; Richter, M. ; Colomé-Tatché, M. ; Martinez Jimenez, C.P.
Single-cell metabolic profiling reveals subgroups of primary human hepatocytes with heterogeneous responses to drug challenge.Wirth, J. ; Huber, N. ; Yin, K. ; Brood, S. ; Chang, S.C.-E. ; Martinez Jimenez, C.P. ; Meier, M.
Spatial transcriptomics using multiplexed deterministic barcoding in tissue.Kolabas, Z.I. ; Kuemmerle, L. ; Perneczky, R. ; Förstera, B. ; Ulukaya, S. ; Ali, M. ; Kapoor, S. ; Bartos, L.M. ; Büttner, M. ; Caliskan, Ö.S. ; Rong, Z. ; Mai, H. ; Höher, L. ; Jeridi, D. ; Molbay, M. ; Khalin, I. ; Deligiannis, I.K. ; Negwer, M. ; Roberts, K. ; Simats, A. ; Carofiglio, O. ; Todorov, M.I. ; Horvath, I. ; Öztürk, F. ; Hummel, S. ; Biechele, G. ; Zatcepin, A. ; Unterrainer, M. ; Gnörich, J. ; Roodselaar, J. ; Shrouder, J. ; Khosravani, P. ; Tast, B. ; Richter, L. ; Díaz-Marugán, L. ; Kaltenecker, D. ; Lux, L. ; Chen, Y. ; Zhao, S. ; Rauchmann, B.S. ; Sterr, M. ; Kunze, I. ; Stanic Aguilera, K.N. ; Kan, V.W.Y. ; Besson-Girard, S. ; Katzdobler, S. ; Palleis, C. ; Schädler, J. ; Paetzold, J.C. ; Liebscher, S. ; Hauser, A.E. ; Gokce, O. ; Lickert, H. ; Steinke, H. ; Benakis, C. ; Braun, C. ; Martinez Jimenez, C.P. ; Buerger, K. ; Albert, N.L. ; Höglinger, G. ; Levin, J. ; Haass, C. ; Kopczak, A. ; Dichgans, M. ; Havla, J. ; Kümpfel, T. ; Kerschensteiner, M. ; Schifferer, M. ; Simons, M. ; Liesz, A. ; Krahmer, N. ; Bayraktar, O.A. ; Franzmeier, N. ; Plesnila, N. ; Erener, S. ; Puelles, V.G. ; Delbridge, C. ; Bhatia, H.S. ; Hellal, F. ; Elsner, M. ; Bechmann, I. ; Ondruschka, B. ; Brendel, M. ; Theis, F.J. ; Ertürk, A.
Distinct molecular profiles of skull bone marrow in health and neurological disorders.Alvarez, L. ; Marín-García, P.J. ; Rentero-Garrido, P. ; Martinez Jimenez, C.P. ; Llobat, L.
Interleukin 6 and interferon gamma haplotypes are related to cytokine serum levels in dogs in an endemic Leishmania infantum region.Strzelecki, M. ; Yin, K. ; Talavera Lopez, C.N. ; Martinez Jimenez, C.P.
Isolation of nuclei from flash-frozen liver tissue for single-cell multiomics.Wolff, G. ; Sakurai, M. ; Mhamane, A. ; Troullinaki, M. ; Maida, A. ; Deligiannis, I.K. ; Yin, K. ; Weber, P. ; Morgenstern, J. ; Wieder, A. ; Kwon, Y. ; Sekar, R. ; Zeigerer, A. ; Roden, M. ; Blüher, M. ; Volk, N. ; Poth, T. ; Hackert, T. ; Wiedmann, L. ; De Angelis Rigotti, F. ; Rodriguez-Vita, J. ; Fischer, A. ; Mukthavaram, R. ; Limphong, P. ; Tachikawa, K. ; Karmali, P. ; Payne, J. ; Chivukula, P. ; Ekim Üstünel, B. ; Martinez Jimenez, C.P. ; Szendrödi, J. ; Nawroth, P.P. ; Herzig, S.
Hepatocyte-specific activity of TSC22D4 triggers progressive NAFLD by impairing mitochondrial function.Yin, K. ; Patten, D. ; Gough, S.C. ; de Barros Gonçalves, S. ; Chan, A. ; Olan, I. ; Cassidy, L. ; Poblocka, M. ; Zhu, H. ; Lun, A. ; Schuijs, M.J. ; Young, A. ; Martinez Jimenez, C.P. ; Halim, T.Y.F. ; Shetty, S. ; Narita, M. ; Hoare, M.
Senescence-induced endothelial phenotypes underpin immune-mediated senescence surveillance.
