Maria Rohm

Group Leader at Institute for Diabetes and Cancer, Research Group Tissue Crosstalk in Cancer Metabolism

Dr. Maria Rohm

"My research addresses the role of tissue crosstalk in the metabolic diseases diabetes, metabolic syndrome, and cancer cachexia. The conjunction of these metabolic diseases is particularly important as their signalling pathways and pathomechanisms overlap"

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Academic Career and Research Areas

Maria studied Biology in Heidelberg, Germany, and Manchester, UK. Having finished her PhD investigating adipose tissue lipolysis in obesity, she then studied adipose tissue function in cancer cachexia at the German Cancer Research Center. Being awarded a Novo Nordisk Postdoctoral Research Fellowship in 2014, she worked at the University of Oxford on the molecular basis of metabolic changes occurring in metabolic diseases, using a multi-omics approach. In 2017, Maria then joined the Institute for Diabetes and Cancer at the Helmholtz Center Munich as a junior group leader, and is now head of the research division "Tissue Crosstalk". Her work on understanding tissue communication and metabolic reprogramming in cachexia has won several prestigious grants most recently the ERC Starting Grant. Being in the Board of Directors and Educational Committee of the Cancer Cachexia Society, Maria is actively engaged in widening research and knowledge about cachexia. As cachexia is a fatal disease with currently no efficient treatment options, which affects a large percentage of patients with cancer, a better understanding of the pathomechanisms will directly aid patients. Maria’s aim for the future is to strengthen the idea that obesity/diabetes and cachexia are two sides of the same coin, and studying these metabolic diseases in the context of each other will lead to conceptual advances in both fields.

Fields of Work and Expertise

Lipid Metabolism Cachexia  Adipose Tissue Glucose Metabolism Diabetes

Professional Background

Since 2020

Head of Research Division at Helmholtz Munich

2017-2020

Junior Group Leader at Helmholtz Munich

2014-2017

Postdoc in Oxford, UK

2012 - 2014

Postdoc at German Cancer Research Center

2012

Dr. rer. nat. in Biology, University of Heidelberg

Honors and Awards

  • 2021 - Vincenz-Czerny Price for Oncology
  • 2020 - ERC Starting Grant
  • 2019 - Lipidology Prize
  • 2013 - Research Award by German Diabetes Society

Highlight Publications

J Cachexia Sarcopenia Muscle

Pauline Morigny,…and Maria Rohm. 2020

High levels of modified ceramides are a defining feature of murine and human cancer cachexia.
Nature Communications

Elizabeth Haythorne, Maria Rohm, ... Frances M Ashcroft 2019

Diabetes causes marked inhibition of mitochondrial metabolism in pancreatic β-cells.
EMBO Reports

Maria Rohm, Anja Zeigerer, Juliano Machado and Stephan Herzig - 2019

Energy metabolism in cachexia.

Networks and Affiliations

Quadratisches Format - ERC Logo

European Research Council

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