Principal Investigator Helmholtz Pioneer Campus
Prof. Dr. Oliver Bruns
“My vision is that, in 10 years, SWIR imaging will be the gold standard for preclinical and clinical imaging. Every research center and every major clinic will have SWIR detection systems and will use novel contrast agents, like those I plan to develop with my team and collaborators. This new generation of optical imaging techniques will enable preclinical contact-free imaging in awake and behaving mice and, in the future, clinical imaging with single-cell sensitivity and penetration depth up to centimeters.”
Research Area
Vision: short-wave infrared region (SWIR) is the future of optical imaging
Professional Background
Head of Department Functional Imaging in Surgical Oncology, NCT Dresden
Principal Investigator Helmholtz Pioneer Campus, Helmholtz Zentrum München
Research Scientist (Senior Scientist), Department of Chemistry at Massachusetts Institute of Technology (MIT)
Postdoctoral Associate in the group of Prof. Moungi Bawendi at Massachusetts Institute of Technology (MIT)
Senior Scientist at Heinrich-Pette-Institute Hamburg/Germany
Honors and Awards
- Emmy Noether Group leader DFG 2018
- EMBO Long-Term Fellowship 2011 - 2013
- DAAD fellowship (declined in favour of EMBO Long-term Fellowship) 2010
- ‘Studienstiftung des Deutschen Volkes’ Fellowship 2006 - 2009
- Travel grant for the World Molecular Imaging Congress 2017
- EMBL Advanced Training Centre Fellowship (Travel grant) and Dr. Wilhelmy-GSO-Fellowship (Travel grant) 2015
- SPOT award by MIT School of Science and Travel grant by MIT PDA 2014
- Karl-Heinz Hölzer Award for Interdisciplinary Medical Research (PhD-Thesis) 2010
- Young Investigator Award, 77th European Atherosclerosis Congress, 2008, Istanbul, Turkey 2008
- Young Investigator Award, 30th annual Meeting of European Lipoprotein Club, Tutzing, Germany 2007
- Award for the best diploma thesis in Biochemistry/Molecular Biology 2006
- Spokesman of the Student Committee of the 'GBM' (German Biochemical Society) 2004 - 2008
Publications
Spearman, A.L. ; Lin, E.Y. ; Mobley, E.B. ; Chmyrov, A. ; Arus, B.A. ; Turner, D.W. ; Garcia, C.A. ; Bui, K. ; Rowlands, C.J. ; Bruns, O.T. ; Sletten, E.M.
High-resolution multicolor shortwave infrared dynamic in vivo imaging with chromenylium nonamethine dyes.Luo, J. ; Molbay, M. ; Chen, Y. ; Horvath, I. ; Kadletz, K. ; Kick, B. ; Zhao, S. ; Al-Maskari, R. ; Singh, I. ; Ali, M. ; Bhatia, H.S. ; Minde, D.-P. ; Negwer, M. ; Höher, L. ; Calandra, G.M. ; Groschup, B. ; Su, J. ; Kimna, C. ; Rong, Z. ; Galensowske, N. ; Todorov, M.I. ; Jeridi, D. ; Ohn, T.-L. ; Roth, S. ; Simats, A. ; Singh, V. ; Khalin, I. ; Pan, C. ; Arus, B.A. ; Bruns, O.T. ; Zeidler, R. ; Liesz, A. ; Protzer, U. ; Plesnila, N. ; Ussar, S. ; Hellal, F. ; Paetzold, J.C. ; Elsner, M. ; Dietz, H. ; Ertürk, A.
Nanocarrier imaging at single-cell resolution across entire mouse bodies with deep learning.Pieczykolan, M. ; Dancer, P.A. ; Klein, T. ; Piwonski, H. ; Rolbieski, H. ; Maity, B. ; Bruns, O.T. ; Cavallo, L. ; Kiessling, F. ; Rueping, M. ; Banala, S.
Small organic fluorophores with SWIR emission detectable beyond 1300 nm.Huang, Y. ; Stankevych, M. ; Gujrati, V. ; Klemm, U. ; Mohammed, A. ; Wiesner, D. ; Saccomano, M. ; Tost, M. ; Feuchtinger, A. ; Mishra, K. ; Bruns, O.T. ; Geerlof, A. ; Ntziachristos, V. ; Stiel, A.-C.
Photoswitching protein-XTEN fusions as injectable optoacoustic probes.Arteaga Cardona, F. ; Madirov, E. ; Popescu, R. ; Wang, D. ; Busko, D. ; Ectors, D. ; Kübel, C. ; Eggeler, Y.M. ; Arus, B.A. ; Chmyrov, A. ; Bruns, O.T. ; Richards, B.S. ; Hudry, D.
Dramatic impact of materials combinations on the chemical organization of core-shell nanocrystals: Boosting the Tm3+ emission above 1600 nm.Wang, F. ; Zhong, Y. ; Bruns, O.T. ; Liang, Y. ; Dai, H.
Author Correction: In vivo NIR-II fluorescence imaging for biology and medicine (Nature Photonics, (2024), 10.1038/s41566-024-01391-5).Wang, F. ; Zhong, Y. ; Bruns, O.T. ; Liang, Y. ; Dai, H.
In vivo NIR-II fluorescence imaging for biology and medicine.Lingg, J.G.P. ; Bischof, T.S. ; Arus, B.A. ; Cosco, E. ; Sletten, E.M. ; Rowlands, C.J. ; Bruns, O.T. ; Chmyrov, A.
Shortwave-infrared line-scan confocal microscope for deep tissue imaging in intact organs.Klein, T. ; Yang, S. ; Tusty, M.A. ; Nayak, J.V. ; Chang, M.T. ; Bruns, O.T. ; Bischof, T.S. ; Valdez, T.A.
Development of a shortwave infrared sinuscope for the detection of cerebrospinal fluid leaks.Arus, B.A. ; Cosco, E. ; Yiu, J. ; Balba, I. ; Bischof, T.S. ; Sletten, E.M. ; Bruns, O.T.
Shortwave infrared fluorescence imaging of peripheral organs in awake and freely moving mice.