Director Institute for Biological and Medical Imaging and Director, Bioengineering Department
Prof. Vasilis Ntziachristos, Msc PhD
“Our research at Helmholtz Munich is driven by our interest to provide solutions that address critical unmet medical needs and positively impact healthcare and the well-being of society.”
Academic Career and Research Areas
Vasilis Ntziachristos’ research focuses on the development of new methods for advancing well-being and accelerating discovery. His focus is the development of novel methods for prevention and early detection of disease, also serving as the means of administering more efficient treatment. His expertise span the fields of imaging, sensing and computation and his activities cover the entire spectrum from theoretical and methodological developments and basic discovery to clinical translation and entrepreneurship. Examples of his work involve the development of Fluorescent Molecular Imaging as means to improve guidance in surgery and the performance of diagnostic endoscopy as well as the development of Optoacoustic Imaging and Microscopy methods for advancing discovery and impacting healthcare. He is the founder of several companies including SurgVision BV which commercializes fluorescence imaging solutions for surgery, now under Bracco SpA, and iThera Medical GmbH, a company that commercializes optoacoustic technology.
Professor Vasilis Ntziachristos studied electrical engineering at Aristotle University in Thessaloniki. Following his M.Sc. and Ph.D. in the Department of Bioengineering at the University of Pennsylvania, he was then appointed Assistant Professor and Director of the Laboratory for Bio-Optics and Molecular Imaging at Harvard University and Massachusetts General Hospital. Since 2007, he has served as Professor of Medicine and Electrical Engineering and the Chair of Biological Imaging at the Technical University of Munich and Director of the Institute of Biological and Medical Imaging at Helmholtz Munich. Prof. Ntziachristos is also currently Director of Bioengineering at the Helmholtz Pioneer Campus and the Head of the Bioengineering Department at Helmholtz Munich.
Fields of Work and Expertise
Imaging
Microscopy
Optoacoustics
Photonics
Clinical Translation
Biological Engineering
Data Analytics Biomedical Engineering
Computational Methods
Machine Learning
Professional Background
Full Professor C4/W3 of Medicine and Electrical Engineering, Chair of Biological Imaging at the Technical University of Munich Director, Institute for Biological and Medical Imaging
Assistant Professor and Director of the Laboratory of Bio-optics and Molecular Imaging, Harvard University and Massachusetts General Hospital
Instructor, Harvard University and Massachusetts General Hospital
Publications
Keizers, B. ; Stroet, M.C.M. ; Ali, M. ; Floru, S. ; Saliën, J. ; Mezzanotte, L. ; Delikatny, E.J. ; Gibbs, S.L. ; Giuliani, S. ; Gioux, S. ; Ingelberts, H. ; Kruijff, S. ; Ntziachristos, V. ; LaRochelle, E. ; Rogalla, S. ; Rosenthal, E.L. ; Samkoe, K.S. ; Tichauer, K.M. ; Vahrmeijer, A.L. ; Witjes, M.J.H. ; Voskuil, F.J. ; Gorpas, D. ; Hernot, S. ; van der Zaag, P.J.
Reflect: Reporting guidelines for preclinical, translational and clinical fluorescence molecular imaging studies.La, T.A. ; Shnaiderman, R. ; Ntziachristos, V.
Amplification of light-ultrasound interaction in a pi-shifted Fiber Bragg grating for enhanced ultrasonic sensitivity.Bader, M. ; Longo, A. ; Jüstel, D. ; Ntziachristos, V.
Low frequency detection in clinical multispectral optoacoustic tomography.Thomas, S.R. ; de Andrade Querino, A.L. ; Moreno-Alcántar, G. ; Tran, T. ; Rodríguez-Prieto, T. ; Qian, S. ; Di Giuseppe, D. ; Anzenhofer,P. ; Ntziachristos, V. ; Silva, H. ; Somoza, V. ; Fischer, R.A. ; Casini, A.
Water-soluble N-heterocyclic carbene stabilized gold nanoparticles by top-down synthesis: Performance in catalysis and photoacoustic imaging.Deußing, M. ; Schuh, S. ; Thamm, J. ; Winkler, D. ; Schneider, S. ; Nau, T. ; Darsow, U. ; Schnabel, V. ; Ulrich, M. ; Nguyen, L.A. ; Frenzel, D. ; Fischer, C. ; Ruini, C. ; Ntziachristos, V. ; Kaatz, M. ; Kurzen, H. ; Kardorff, B. ; Herbst, R. ; Grunewald, S. ; Sattler, E. ; Welzel, J. ; Hartmann, D.
S1 guideline for imaging diagnostics for skin diseases.Li, Q. ; Ali, Z. ; Zakian, C. ; Di Pietro, M. ; Honing, J. ; O'Donovan, M. ; Flisikowski, K. ; Sarantos, V. ; Pierre, G. ; Gloriod, J. ; Drexler, W. ; Ntziachristos, V.
Tethered optoacoustic and optical coherence tomography capsule endoscopy for label-free assessment of Barrett's oesophageal neoplasia.Gehmeyr, M. ; Rojas López, M.B. ; Nitkunanantharajah, S. ; Preissl, H. ; Vosseler, A. ; Jumpertz von Schwartzenberg, R. ; Birkenfeld, A.L. ; Katsouli, N. ; Fasoula, N. ; Karlas, A. ; Kallmayer, M. ; Ziegler, A.-G. ; Jüstel, D. ; Ntziachristos, V.
Enhanced maximum intensity projection (eMIP) for improving the fidelity of optoacoustic images.Rauschendorfer, P. ; Thrapp, A. ; Srinivas, A. ; Carleton, R. ; Mauskapf, A. ; Griffin, K.N.R. ; Ntziachristos, V. ; Tearney, G.J. ; Jaffer, F.A.
High-speed intravascular near-infrared fluorescence-ultrasound imaging In vivo.Prebeck, A. ; Keulemans, G. ; Stahl, U. ; Jans, H. ; Rottenberg, X. ; Ntziachristos, V.
Comparison of bulk piezoelectric and opto-mechanical micromachined detectors for optoacoustic and ultrasound sensing.Ko, V. ; Goess, M.C. ; Platz, L.I. ; Yuan, T. ; Chmyrov, A. ; Jüstel, D. ; Ruland, J. ; Ntziachristos, V. ; Keppler, S.J. ; Pleitez, M.A.
Author Correction: Fast histological assessment of adipose tissue inflammation by label-free mid-infrared optoacoustic microscopy.Aguirre Bueno, J. ; Ntziachristos, V.
Response to letter to editor (doi: 10.1111/jdv.20888) on UWB-RSOM in melanoma depth assessment.Berger, C. ; Kim, M. ; Platz, L.I. ; Eigenberger, A. ; Prantl, L. ; Liu, P. ; Gujrati, V. ; Ntziachristos, V. ; Jüstel, D. ; Pleitez, M.A.
Bayesian reconstruction of rapidly scanned mid-infrared optoacoustic signals enables fast, label-free chemical microscopy.Englert, L. ; Perleberg, B. ; Tayal, S. ; Wang, B. ; Huang, Y. ; Azeem, M. ; He, H. ; Stiel, A.-C. ; Ntziachristos, V.
Assessment of performance characteristics of photoswitchable bacteriophytochromes at different depths using optoacoustic mesoscopy.Gasparin, F. ; Tietje, M.R. ; Katab, E. ; Nurdinova, A. ; Yuan, T. ; Chmyrov, A. ; Uluc, N. ; Jüstel, D. ; Bassermann, F. ; Ntziachristos, V. ; Pleitez, M.A.
Label-free protein-structure-sensitive live-cell microscopy for patient-specific assessment of myeloma therapy.Aguirre Bueno, J. ; Gasteiger, C. ; Hindelang, B. ; Seeger, M. ; Berezhnoi, A. ; Weidenfeld, I. ; Darsow, U. ; Stiel, A.-C. ; Steimle-Grauer, S.A. ; Posch, C. ; Biedermann, T. ; Ntziachristos, V.
Non-invasive characterization of melanoma depth at single-cell resolution.Kriukova, E. ; Mazurenka, M. ; Marcazzan, S. ; Tschurtschenthaler, M. ; Puppels, G.J. ; Glasl, S. ; Saur, D. ; Jesinghaus, M. ; Pouliou, M. ; Agelopoulos, M. ; Klinakis, A. ; Quante, M. ; Ripoll, J. ; Ntziachristos, V. ; Gorpas, D.
Probing field cancerization in the gastrointestinal tract using a hybrid raman and partial wave spectroscopy microscope.Dehner, C. ; Lilaj, L. ; Ntziachristos, V. ; Zahnd, G. ; Jüstel, D.
Scale-equivariant deep model-based optoacoustic image reconstruction.Bader, M. ; Mc Larney, B.E. ; Pinker, K. ; Grimm, J. ; Jüstel, D. ; Ntziachristos, V.
Deciphering the spectra of breast cancer in multispectral optoacoustic tomography.Gorpas, D. ; Ntziachristos, V.
Multi-parametric standards for performance assessment and quality control of fluorescence molecular imaging and endoscopy systems.Malekzadeh Najafabadi, J. ; Prakash, J. ; Razansky, D. ; Ripoll, J. ; Gujrati, V. ; Ntziachristos, V.
Nonlinearity of optoacoustic signals and a new contrast mechanism for imaging.