Director Institute for Biological and Medical Imaging and Director, Bioengineering Department
Prof. Vasilis Ntziachristos, Msc PhD
“Our research at Helmholtz Munich is driven by our interest to provide solutions that address critical unmet medical needs and positively impact healthcare and the well-being of society.”
Academic Career and Research Areas
Vasilis Ntziachristos’ research focuses on the development of new methods for advancing well-being and accelerating discovery. His focus is the development of novel methods for prevention and early detection of disease, also serving as the means of administering more efficient treatment. His expertise span the fields of imaging, sensing and computation and his activities cover the entire spectrum from theoretical and methodological developments and basic discovery to clinical translation and entrepreneurship. Examples of his work involve the development of Fluorescent Molecular Imaging as means to improve guidance in surgery and the performance of diagnostic endoscopy as well as the development of Optoacoustic Imaging and Microscopy methods for advancing discovery and impacting healthcare. He is the founder of several companies including SurgVision BV which commercializes fluorescence imaging solutions for surgery, now under Bracco SpA, and iThera Medical GmbH, a company that commercializes optoacoustic technology.
Professor Vasilis Ntziachristos studied electrical engineering at Aristotle University in Thessaloniki. Following his M.Sc. and Ph.D. in the Department of Bioengineering at the University of Pennsylvania, he was then appointed Assistant Professor and Director of the Laboratory for Bio-Optics and Molecular Imaging at Harvard University and Massachusetts General Hospital. Since 2007, he has served as Professor of Medicine and Electrical Engineering and the Chair of Biological Imaging at the Technical University of Munich and Director of the Institute of Biological and Medical Imaging at Helmholtz Munich. Prof. Ntziachristos is also currently Director of Bioengineering at the Helmholtz Pioneer Campus and the Head of the Bioengineering Department at Helmholtz Munich.
Fields of Work and Expertise
Imaging
Microscopy
Optoacoustics
Photonics
Clinical Translation
Biological Engineering
Data Analytics Biomedical Engineering
Computational Methods
Machine Learning
Professional Background
Full Professor C4/W3 of Medicine and Electrical Engineering, Chair of Biological Imaging at the Technical University of Munich Director, Institute for Biological and Medical Imaging
Assistant Professor and Director of the Laboratory of Bio-optics and Molecular Imaging, Harvard University and Massachusetts General Hospital
Instructor, Harvard University and Massachusetts General Hospital
Publications
Ülgen, O. ; La, T.A. ; Zakian, C. ; Gotsch, M. ; Ntziachristos, V.
150 MHz polymer resonator for optoacoustic mesoscopy based on a tapered optical fiber.Gasparin, F. ; Ntziachristos, V.
Optoacoustic microscopy for detecting lipid fingerprints in living cells.Bader, M. ; Sridharan, P. ; Fragkiadakis, E. ; Mc Larney, B.E. ; Martirosyan, S. ; Gujrati, V. ; Anzenhofer, P. ; Pinker, K. ; Grimm, J. ; Jüstel, D. ; Curren, I.S. ; Ntziachristos, V.
Comparing Vascular Contrast of Breast Cancer in Multispectral Optoacoustic Tomography Above and Below 1000 Nanometers.Kim, M. ; Berger, C. ; Wolf, A. ; Peteranderl, A. ; Klingenspor, M. ; Ntziachristos, V. ; Li, Y. ; Pleitez, M.A.
Single-cell metabolic imaging and digital scoring of fat tissue remodeling by label-free metabolic microscopy.Gasparin, F. ; Prebeck, A. ; Solda, A. ; Uluc, N. ; Glasl, S. ; Berger, C. ; Pleitez, M.A. ; Ntziachristos, V.
Differentiation of sphingomyelin and cholesterol by hyperspectral mid-infrared detection of single-bond vibrational modes in the fingerprint region.Kukacka, J. ; Bader, M. ; Jüstel, D. ; Ntziachristos, V.
Motion score for spectral quality control of optoacoustic-ultrasound data.He, H. ; Karlas, A. ; Fasoula, N.-A. ; Fischer, C. ; Darsow, U. ; Kallmayer, M. ; Aguirre Bueno, J. ; Eckstein, H.H. ; Ntziachristos, V.
Single-capillary endothelial dysfunction resolved by optoacoustic mesoscopy.Fasoula, N.-A. ; Katsouli, N. ; Kallmayer, M. ; Ntziachristos, V. ; Karlas, A.
Mapping glucose-induced hemodynamics in white fat depots with label-free optoacoustics.Stiel, A.-C. ; Niessing, D. ; Ntziachristos, V. ; Chmyrov, A.
Sense and switch across scales – Prototyping genetically encoded, reversibly switchable indicators for sub-diffraction microscopy and whole animal optoacoustic Ca2+ imaging.Ricciardi, L. ; Rauschendorfer, P. ; Gorpas, D. ; Ntziachristos, V.
Importance of Distance Correction in Near-Infrared and Intravascular Ultrasound imaging for Reliable Assessment of the Cardiovascular Tissue Pathobiological State.Tenditnaya, A. ; Kriukova, E. ; Gabriëls, R.Y. ; Nagengast, W.B. ; Ntziachristos, V. ; Gorpas, D.
Influence of Sensitivity Metrics Definition on Fluorescence Molecular Endoscopy (FME) Systems Performance Assessment and Quality Control.Ross, A.G. ; Di Giuseppe, D. ; Vaghela, R. ; Selzner, D. ; Chen, S. ; Köhler, P. ; Ntziachristos, V.
Optoacoustic mesoscopy based on laser diodes.Berger, C. ; Kim, M. ; Platz, L.I. ; Eigenberger, A. ; Prantl, L. ; Liu, P. ; Gujrati, V. ; Ntziachristos, V. ; Jüstel, D. ; Pleitez, M.A.
Setting the stage for intraoperative histological quality guidance in autologous fat treatments via computed optoacoustic microscopy.He, H. ; Paetzold, J.C. ; Börner, N. ; Riedel, E. ; Gerl, S. ; Schneider, S. ; Fisher, C. ; Ezhov, I. ; Shit, S. ; Li, H. ; Rückert, D. ; Aguirre, J. ; Biedermann, T. ; Darsow, U. ; Menze, B. ; Ntziachristos, V.
Automatic quantification of human skin anatomy and microvasculature biomarkers by optoacoustic mesoscopy with machine learning.Bader, M. ; Mc Larney, B.E. ; Pinker, K. ; Grimm, J. ; Jüstel, D. ; Ntziachristos, V.
Towards obtaining reliable spectral biomarkers of breast cancer in multispectral optoacoustic tomography.Ul Alam, S. ; Kriukova, E. ; Mazurenka, M. ; Marcazzan, S. ; Glasl, S. ; Quante, M. ; Tschurtschenthaler, M. ; Puppels, G.J. ; Ntziachristos, V. ; Gorpas, D.
Enhancing characterization of chemical and morphological changes in tissue with a hybrid Raman and partial wave spectroscopy system.Gehmeyr, M. ; Rojas López, M.B. ; Nitkunanantharajah, S. ; Preißl, H. ; Vosseler, A. ; Jumpertz Von Schwartzenberg, R. ; Birkenfeld, A.L. ; Jüstel, D. ; Ntziachristos, V.
Skin flattening of raster-scan optoacoustic mesoscopy (RSOM) reconstructions based on polynomial fitting.Rojas López, M.B. ; Gehmeyr, M. ; Nitkunanantharajah, S. ; Preissl, H. ; Vosseler, A. ; Jumpertz Von Schwartzenberg, R. ; Birkenfeld, A.L. ; Jüstel, D. ; Ntziachristos, V.
Automatic real-time quality assessment for optoacoustic mesoscopy data.Englert, L. ; Lacalle-Aurioles, M. ; Mohamed, N.V. ; Lépine, P. ; Mathur, M. ; Ntziachristos, V. ; Durcan, T.M. ; Aguirre Bueno, J.
Neuromelanin imaging in entire human midbrain organoids using optoacoustic mesoscopy.Deußing, M. ; Schuh, S. ; Thamm, J. ; Winkler, D. ; Schneider, S. ; Nau, T. ; Darsow, U. ; Schnabel, V. ; Ulrich, M. ; Nguyen, L.A. ; Frenzel, D. ; Fischer, C. ; Ruini, C. ; Ntziachristos, V. ; Kaatz, M. ; Kurzen, H. ; Kardorff, B. ; Herbst, R. ; Grűnewald, S. ; Sattler, E. ; Welzel, J. ; Hartmann, D.
S1‐Leitlinie für bildgebende Diagnostik von Hauterkrankungen.