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Institut für Diabetesforschung Studienzentrum

For ten years, the Fr1da study, coordinated by Helmholtz Munich, has been investigating whether early stages of type 1 diabetes in children can be detected in routine pediatric care. The latest evaluation shows that the screening program is…

Screenshot pancreas für research area "type 1 diabetes pathology" (Teresa Rodgriguez-Calvo)

Dr. Teresa Rodriguez-Calvo from Helmholtz Munich has been awarded two prestigious grants from Breakthrough T1D, the leading global type 1 diabetes (T1D) research and advocacy organization. The funding will support two innovative projects at the…

As part of the Fr1da study, “Early detection and early treatment of type 1 diabetes”, led by researchers at the Institute of Diabetes Research at Helmholtz Munich, families can have their children aged two to ten tested for an early stage of type 1…

Portrait Anette Gabriele Ziegler, Querformat;

Prof. Anette-Gabriele Ziegler from Helmholtz Munich has been named the recipient of the 58th Claude Bernard Prize, the highest honor awarded by the European Association for the Study of Diabetes (EASD). The prize recognizes her outstanding leadership…

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A population-based cohort study provides new data on the prevalence of early-stage type 1 diabetes in young adults, addressing a gap in epidemiological research. Using samples from the LISA and GINIplus cohorts and methodologies established in the…

EDENT1FI (“European action for the Diagnosis of Early Non-clinical Type 1 diabetes For disease Interception”), a research project led by Prof. Anette-Gabriele Ziegler from Helmholtz Munich and Prof. Chantal Mathieu from the KU Leuven, has reached an…

Helmholtz Munich has been awarded a prestigious grant of up to 900 000 US Dollar from Breakthrough T1D, the leading global type 1 diabetes (T1D) research and advocacy organization. The funding will support the research into early-stage T1D in adults,…

Prof. Sandra Hummel, lead scientist of the research area “Lifestyle, Obesity, and Epigenetic Programming in Type 1 and Gestational Diabetes” at the Institute of Diabetes Research at Helmholtz Munich, has been awarded the Dr. Heinz Bürger-Büsing…

First results of the Primary Oral Insulin Trial (POInT) mark an important step towards the prevention of type 1 diabetes, pointing future efforts to personalized strategies. The group led by researchers from Helmholtz Munich and the Technical…

Schwangere Frau sieht sich Ultraschallbilder an

Children with a family history of type 1 diabetes (T1D) have an increased risk of developing the disease. However, children born to mothers with T1D are less likely to develop the disease than those whose fathers or siblings have T1D. A new study…

Prof. Anette-Gabriele Ziegler, Director of the Helmholtz Munich Institute for Diabetes Research, is awarded with this year’s Hamm International Prize. She is being honored for her research to understand the pathogenesis of type 1 diabetes and efforts…

Vierte Helmholtz Munich Expert Hour im Deutschen Bundestag

Science and politics came together once again at the German Bundestag: For the fourth time, Helmholtz Munich hosted the Helmholtz Munich Expert Hour on September 10, 2025. This dialogue format gives political decision-makers the opportunity to learn…

kind-spielt-institut-fotoshooting-nozy-andreas pfohl-220727_0587 mit Logofr1da

The Helmholtz Munich Institute for Diabetes Research has been awarded a grant of over 1 Mio. Dollar from Breakthrough T1D, a global organization focused on type 1 diabetes research and advocacy, to intensify the longstanding Fr1da-Cohort-Study. The…

3D representation of insulin protein structure illuminated with a blue glow on a black background

At this year’s Congress of the German Diabetes Association (DDG), three researchers from Helmholtz Munich were honored for their outstanding scientific achievements. Their groundbreaking work is helping to advance the understanding, prevention, and…

Starting May 1, 2025, the pioneering study “Fr1da” for early detection of type 1 diabetes will expand into the German states of Hesse and Rhineland-Palatinate. Pediatric practices in these regions will then be able to offer families with children…

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A new study, led by Prof. Eleftheria Zeggini, Director of the Institute of Translational Genomics at Helmholtz Munich, and Prof. Anette-Gabriele Ziegler, Director of the Institute of Diabetes Research at Helmholtz Munich, has revealed a significant…

The clinical onset of type 1 diabetes is preceded by presymptomatic stages, that are marked by the presence of two or more islet autoantibodies. Stage 1 is characterized by normal blood glucose levels, while stage 2 is marked by dysglycemia. However,…

Almost nine million people are living with type 1 diabetes worldwide. Although this disease can be a life-threatening, it often goes unnoticed and is diagnosed too late. Yet type 1 diabetes can be diagnosed early, long before symptoms appear, by a…

The Type 1 Diabetes Grand Challenge, a partnership between the Steve Morgan Foundation, Diabetes UK, and Breakthrough T1D, formerly JDRF, has announced funding for a cutting-edge research project led by researchers at Helmholtz Munich and the…

Every year on October 3rd, the German broadcaster WDR organizes the event "Doors Open with The Mouse." This year, 770 companies and research institutions across Germany participated, welcoming children and parents under the theme "Working Together."…

Rachmiel Levine Award for Anette-Gabriele Ziegler

Prof. Anette-Gabriele Ziegler, Director of the Helmholtz Munich Institute for Diabetes Research, was awarded the 2024 Rachmiel Levine Medal by City of Hope - a prominent biomedical research and treatment institution in the United States, especially…

Experts from the Helmholtz Munich-led Fr1daPlex initiative, the Bavarian Professional Association of Pediatricians (BVKJ), and PaedNetz Bayern e.V. have published a new position paper providing a detailed evaluation of an islet autoantibody screening…

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A new evaluation of data from children with early-stage type 1 diabetes during the COVID-19 pandemic shows an accelerated progression from the presymptomatic early stage to clinical onset of type 1 diabetes in children with a SARS-CoV-2 infection.…

Islet autoimmunity, which underlies the development of type 1 diabetes (T1D), is influenced by various environmental factors, including early childhood viral infections. Scientists from the GPPAD consortium, coordinated at Helmholtz Munich, recently…

The diagnosis of type 1 diabetes often comes with serious complications for families, as the autoimmune disease is frequently detected only after severe symptoms develop. Early detection of type 1 diabetes through population-wide screening offers…

This year, the highest award of the German Diabetes Association (DDG) – the Paul Langerhans Medal – is awarded to Prof. Dr. med. Anette-Gabriele Ziegler. The Director of the Institute of Diabetes Research at Helmholtz Munich and scientist at the…

Happy millennial african american mother kissing little child, enjoy relax together, have fun in bedroom interior

Type 1 diabetes is an autoimmune disease that leads to disrupted glucose metabolism. It requires lifelong insulin therapy. The Global Platform for the Prevention of Autoimmune Diabetes (GPPAD) collaborates within a European network to develop new…

Prof. Anette-Gabriele Ziegler about her contribution to novel therapies for type 1 diabetes.

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Pediatricians and computer scientists join forces at the Helmholtz Munich Institute for Diabetes Research to identify children with type 1 diabetes before they develop symptoms. With the help of advanced statistics and machine learning, the…

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In a groundbreaking collaborative effort, academic researchers, industry leaders, and charities have joined forces to combat Type 1 Diabetes (T1D) with the support of a €22 million grant from the Innovative Health Initiative (IHI). EDENT1FI, which…

Early Detection of Type 1 Diabetes in Children Is Broadly Feasible

New Funding Supports Research into Causes and Treatment of Type 1 Diabetes

Fr1da Study Expands Early Diabetes Detection to 12 German Federal States

Anette-Gabriele Ziegler Receives Claude Bernard Prize for Diabetes Research

Rethinking Early Detection: Type 1 Diabetes in Young Adults

100,000 Participants Screened for Early-Stage Type 1 Diabetes in the EDENT1FI Project

Helmholtz Munich Secures Funding to Investigate Early-Stage Type 1 Diabetes in Adults

Sandra Hummel Awarded the Dr. Heinz Bürger-Büsing Prize

New Milestone Towards Personalized Prevention of Type 1 Diabetes

Maternal Type 1 Diabetes May Protect Children Through Epigenetic Changes

Anette-Gabriele Ziegler Receives Hamm International Prize for Diabetes Research

Helmholtz Munich Expert Hour at the German Bundestag: The Future of Preventive Medicine

Fr1da-Cohort-Study Receives Grant to Facilitate the Integration of Early-Stage Type 1 Diabetes Screening Into Standard Care

DDG Recognizes Three Researchers from Helmholtz Munich

Early Detection of Type 1 Diabetes in Children: From May 2025 also available in Hesse and Rhineland-Palatinate

Genetic Connection Between Newborn Blood Proteins and Type 1 Diabetes

Definition of Dysglycemia in Pre-symptomatic Type 1 Diabetes: A Guide to the Timing of Interventional Therapies

World Diabetes Day on November 14: Focus On Education and Early Detection of Diabetes

Funding for MicroRNA Research to Enhance Therapies in Type 1 Diabetes

Helmholtz Munich Opened Its Doors for "The Mouse"

Anette-Gabriele Ziegler Awarded Prestigious Rachmiel Levine Medal

Early Detection of Type 1 Diabetes: New Position Paper Published

COVID-19 Pandemic Accelerates Onset of Clinical Type 1 Diabetes

Insights From the COVID-19 Pandemic: Change in Infection History and Islet Autoimmunity Incidence

Population-Wide Screening for Early-Stage Type 1 Diabetes in Children: Opportunities and Challenges in Pediatric Care

Anette-Gabriele Ziegler receives the Paul Langerhans Medal

SARS-CoV-2 and Type 1 Diabetes in Children: New Study Aims to Explore the Relationship

Prediction and Prevention are Key for Counteracting Type 1 Diabetes

Developing Algorithms to Predict Type 1 Diabetes in Children

European Partnership to Combat Type 1 Diabetes Receives €23 Million IHI Funding