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Marvian, A.T. ; Strauss, T. ; Tang, Q. ; Tuck, B.J. ; Keeling, S. ; Rüdiger, D. ; Mirzazadeh Dizaji, N. ; Mohammad-Beigi, H. ; Nuscher, B. ; Chakraborty, P. ; Sutherland, D.S. ; McEwan, W.A. ; Köglsperger, T. ; Zahler, S. ; Zweckstetter, M. ; Lichtenthaler, S.F. ; Wurst, W. ; Schwarz, S. ; Höglinger, G.
Distinct regulation of Tau Monomer and aggregate uptake and intracellular accumulation in human neurons.Hasenbein, T.P. ; Hoelzl, S. ; Smith, Z.D. ; Gerhardinger, C. ; Gonner, M.O.C. ; Aguilar-Pimentel, J.A. ; Amarie, O.V. ; Becker, L. ; Calzada-Wack, J. ; Dragano, N.R.V. ; da Silva Buttkus, P. ; Garrett, L. ; Hölter, S.M. ; Kraiger, M. ; Östereicher, M.A. ; Rathkolb, B. ; Sanz-Moreno, A. ; Spielmann, N. ; Wurst, W. ; Gailus-Durner, V. ; Fuchs, H. ; Hrabě de Angelis, M. ; Meissner, A. ; Engelhardt, S. ; Rinn, J.L. ; Andergassen, D.
X-linked deletion of Crossfirre, Firre, and Dxz4 in vivo uncovers diverse phenotypes and combinatorial effects on autosomes.Wu, J. ; Kislinger, G. ; Duschek, J. ; Durmaz, A.D. ; Wefers, B. ; Feng, R. ; Nalbach, K. ; Wurst, W. ; Behrends, C. ; Schifferer, M. ; Simons, M.
Nonvesicular lipid transfer drives myelin growth in the central nervous system.Garrett, L. ; Trümbach, D. ; Lee, D. ; Mandillo, S. ; Samaco, R.C. ; Flenniken, A.M. ; Stewart, M. ; White, J.K. ; McKerlie, C. ; Nutter, L.M.J. ; Vukobradovic, I. ; Veeraragavan, S. ; Yuva, L. ; Heaney, J.D. ; Dickinson, M.E. ; Meziane, H. ; Hérault, Y. ; Wells, S. ; Lloyd, K.C.K. ; Bower, L. ; Lanoue, L. ; Clary, D. ; Zimprich, A. ; Gailus-Durner, V. ; Fuchs, H. ; Brown, S.D.M. ; Chesler, E.J. ; Wurst, W. ; Hrabě de Angelis, M. ; Hölter, S.M.
Co-expression of prepulse inhibition and Schizophrenia genes in the mouse and human brain.Kaji, S. ; Berghoff, S.A. ; Spieth, L. ; Schlaphoff, L. ; Sasmita, A.O. ; Vitale, S. ; Büschgens, L. ; Kedia, S. ; Zirngibl, M. ; Nazarenko, T. ; Damkou, A. ; Hosang, L. ; Depp, C. ; Kamp, F. ; Scholz, P. ; Ewers, D. ; Giera, M. ; Ischebeck, T. ; Wurst, W. ; Wefers, B. ; Schifferer, M. ; Willem, M. ; Nave, K.A. ; Haass, C. ; Arzberger, T. ; Jäkel, S. ; Wirths, O. ; Saher, G. ; Simons, M.
Apolipoprotein E aggregation in microglia initiates Alzheimer's disease pathology by seeding β-amyloidosis.Hölter, S.M. ; Garrett, L. ; Bludau, S. ; Amunts, K.
Digital tools of analysis and data integration facilitate synergy between mouse and human brain research and enable translation.Xu, M. ; Ito-Kureha, T. ; Kang, H.-S. ; Chernev, A. ; Raj, T. ; Höfig, K.P. ; Hohn, C. ; Giesert, F. ; Wang, Y. ; Pan, W. ; Ziętara, N. ; Straub, T. ; Feederle, R. ; Daniel, C. ; Adler, B. ; König, J. ; Feske, S. ; Tsokos, G.C. ; Wurst, W. ; Urlaub, H. ; Sattler, M. ; Kisielow, J. ; Wulczyn, F.G. ; Łyszkiewicz, M. ; Heissmeyer, V.
Correction to "The thymocyte-specific RNA-binding protein Arpp21 provides TCR repertoire diversity by binding to the 3'-UTR and promoting Rag1 mRNA expression".Wang, M. ; Flaswinkel, H. ; Joshi, A. ; Napoli, M. ; Masgrau-Alsina, S. ; Kamper, J.M. ; Henne, A. ; Heinz, A. ; Berouti, M. ; Schmacke, N.A. ; Hiller, K. ; Kremmer, E. ; Wefers, B. ; Wurst, W. ; Sperandio, M. ; Ruland, J. ; Fröhlich, T. ; Hornung, V.
Phosphorylation of PFKL regulates metabolic reprogramming in macrophages following pattern recognition receptor activation.Lind-Holm Mogensen, F. ; Sousa, C. ; Ameli, C. ; Badanjak, K. ; Pereira, S.L. ; Muller, A. ; Kaoma, T. ; Coowar, D. ; Scafidi, A. ; Poovathingal, S.K. ; Tziortziou, M. ; Antony, P.M.A. ; Nicot, N. ; Ginolhac, A. ; Vogt Weisenhorn, D.M. ; Wurst, W. ; Poli, A. ; Nazarov, P.V. ; Skupin, A. ; Grünewald, A. ; Michelucci, A.
PARK7/DJ-1 deficiency impairs microglial activation in response to LPS-induced inflammation.Beaufort, N. ; Ingendahl, L. ; Merdanovic, M. ; Schmidt, A. ; Podlesainski, D. ; Richter, T. ; Neumann, T. ; Kuszner, M. ; Vetter, I.R. ; Stege, P. ; Burston, S.G. ; Filipovic, A. ; Ruiz-Blanco, Y.B. ; Bravo-Rodriguez, K. ; Mieres-Perez, J. ; Beuck, C. ; Uebel, S. ; Zobawa, M. ; Schillinger, J. ; Malik, R. ; Todorov-Völgyi, K. ; Rey, J. ; Roberti, A. ; Hagemeier, B. ; Wefers, B. ; Müller, S.A. ; Wurst, W. ; Sanchez-Garcia, E. ; Zimmermann, A. ; Hu, X.Y. ; Clausen, T. ; Huber, R. ; Lichtenthaler, S.F. ; Schmuck, C. ; Giese, M. ; Kaiser, M. ; Ehrmann, M. ; Dichgans, M.
Rational correction of pathogenic conformational defects in HTRA1.Sen, P. ; Ortiz, O. ; Brivio, E. ; Menegaz, D. ; Sotillos Elliott, L. ; Du, Y. ; Ries, C. ; Chen, A. ; Wurst, W. ; Lopez, J.P. ; Eder, M. ; Deussing, J.M.
A bipolar disorder-associated missense variant alters adenylyl cyclase 2 activity and promotes mania-like behavior.Hönes, G.S. ; Geist, D. ; Wenzek, C. ; Pfluger, P.T. ; Müller, T.D. ; Aguilar-Pimentel, J.A. ; Amarie, O.V. ; Becker, L. ; Dragano, N.R.V. ; Garrett, L. ; Hölter, S.M. ; Rathkolb, B. ; Rozman, J. ; Spielmann, N. ; Treise, I. ; Wolf, E. ; Wurst, W. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Führer, D. ; Moeller, L.C.
Comparative phenotyping of mice reveals canonical and noncanonical physiological functions of TRα and TRβ.Dunot, J. ; Moreno, S.G. ; Gandin, C. ; Pousinha, P.A. ; Amici, M. ; Dupuis, J. ; Anisimova, M. ; Winschel, A. ; Uriot, M. ; Petshow, S.J. ; Mensch, M. ; Bethus, I. ; Giudici, C. ; Hampel, H. ; Wefers, B. ; Wurst, W. ; Naumann, R. ; Ashby, M.C. ; Laube, B. ; Zito, K. ; Mellor, J.R. ; Groc, L. ; Willem, M. ; Marie, H.
APP fragment controls both ionotropic and non-ionotropic signaling of NMDA receptors.Nguyen, N.K. ; Schroll, R. ; Dörfler, U. ; Suhadolc, M. ; Welzl, G. ; Barış, H.T. ; Munch, J.-C. ; Hoang, G.H. ; Tran, H.T. ; Ying, D.T.Y.
Linkage between glyphosate adsorption/desorption and mineralization in Central European agricultural soils.Gruber, C. ; Krautner, L. ; Bergant, V. ; Grass, V. ; Ma, Z. ; Rheinemann, L. ; Krus, A. ; Reinhardt, F. ; Mazneykova, L. ; Rocha-Hasler, M. ; Truong, D.J.J. ; Westmeyer, G.G. ; Pichlmair, A. ; Ebert, G. ; Giesert, F. ; Wurst, W.
Engineered, nucleocytoplasmic shuttling Cas13d enables highly efficient cytosolic RNA targeting.Vitale, C. ; Natali, G. ; Cerullo, M.S. ; Floß, T. ; Michetti, C. ; Grasselli, G. ; Benfenati, F.
The homeostatic effects of the RE-1 silencing transcription factor on cortical networks are altered under ictogenic conditions in the mouse.Giusti, S.A. ; Pino, N.S. ; Pannunzio, C. ; Ogando, M.B. ; Armando, N.G. ; Garrett, L. ; Zimprich, A. ; Becker, L. ; Gimeno, M.L. ; Lukin, J. ; Merino, F.L. ; Pardi, M.B. ; Pedroncini, O. ; Di Mauro, G.C. ; Gailus-Durner, V. ; Fuchs, H. ; Hrabě de Angelis, M. ; Patop, I.L. ; Turck, C.W. ; Deussing, J.M. ; Vogt Weisenhorn, D.M. ; Jahn, O. ; Kadener, S. ; Hölter, S.M. ; Brose, N. ; Giesert, F. ; Wurst, W. ; Marin-Burgin, A. ; Refojo, D.
A brain-enriched circular RNA controls excitatory neurotransmission and restricts sensitivity to aversive stimuli.Shmal, D. ; Mantero, G. ; Floß, T. ; Benfenati, F. ; Maya-Vetencourt, J.F.
Restoring vision in adult amblyopia by enhancing plasticity through deletion of the transcriptional repressor REST.Hembach, S. ; Schmidt, S. ; Orschmann, T. ; Burtscher, I. ; Lickert, H. ; Giesert, F. ; Weisenhorn, D.M. ; Wurst, W.
Engrailed 1 deficiency induces changes in ciliogenesis during human neuronal differentiation.Xu, M. ; Ito-Kureha, T. ; Kang, H.-S. ; Chernev, A. ; Raj, T. ; Höfig, K.P. ; Hohn, C. ; Giesert, F. ; Wang, Y. ; Pan, W. ; Ziętara, N. ; Straub, T. ; Feederle, R. ; Daniel, C. ; Adler, B. ; König, J. ; Feske, S. ; Tsokos, G.C. ; Wurst, W. ; Urlaub, H. ; Sattler, M. ; Kisielow, J. ; Wulczyn, F.G. ; Łyszkiewicz, M. ; Heissmeyer, V.
The thymocyte-specific RNA-binding protein Arpp21 provides TCR repertoire diversity by binding to the 3'-UTR and promoting Rag1 mRNA expression.Truong, D.J.J. ; Geilenkeuser, J. ; Wendel, S.V. ; Wilming, J.C.H. ; Armbrust, N. ; Binder, E.M.H. ; Santl, T. ; Siebenhaar, A. ; Gruber, C. ; Phlairaharn, T. ; Živanić, M. ; Westmeyer, G.G.
Exonuclease-enhanced prime editors.Leu, C.-L. ; Lam, D.D. ; Salminen, A.V. ; Wefers, B. ; Becker, L. ; Garrett, L. ; Rozman, J. ; Wurst, W. ; Hrabě de Angelis, M. ; Hölter, S.M. ; Winkelmann, J. ; Williams, R.H.
A patient-enriched MEIS1 coding variant causes a restless legs syndrome-like phenotype in mice.Sabikunnahar, B. ; Caldwell, S. ; Varnum, S. ; Hogan, T. ; Lahue, K.G. ; Rathkolb, B. ; Gerlini, R. ; Dragano, N.R.V. ; Aguilar-Pimentel, J.A. ; Irmler, M. ; Sanz-Moreno, A. ; da Silva Buttkus, P. ; Beckers, J. ; Wolf, E. ; Gailus-Durner, V. ; Fuchs, H. ; Hrabě de Angelis, M. ; Ather, J.L. ; Poynter, M.E. ; Krementsov, D.N. ; German Mouse Clinic Consortium (Hölter, S.M. ; Wurst, W.)
LncRNA U90926 is dispensable for the development of obesity-associated phenotypes in vivo.Garrett, L. ; Irmler, M. ; Baljuls, A. ; Rathkolb, B. ; Dragano, N.R.V. ; Gerlini, R. ; Sanz-Moreno, A. ; Aguilar-Pimentel, J.A. ; Becker, L. ; Kraiger, M. ; Reithmeir, R. ; Beckers, J. ; Calzada-Wack, J. ; Wurst, W. ; Fuchs, H. ; Gailus-Durner, V. ; Zimmermann, T. ; Hölter, S.M. ; Hrabě de Angelis, M.
GPR101 loss promotes insulin resistance and diet-induced obesity risk.Riedhammer, K.M. ; Nguyen, T.T. ; Koşukcu, C. ; Calzada-Wack, J. ; Li, Y. ; Batzir, N.A. ; Saygılı, S. ; Wimmers, V. ; Kim, G.J. ; Chrysanthou, M. ; Bakey, Z. ; Sofrin-Drucker, E. ; Kraiger, M. ; Sanz-Moreno, A. ; Amarie, O.V. ; Rathkolb, B. ; Klein-Rodewald, T. ; Garrett, L. ; Hölter, S.M. ; Seisenberger, C. ; Haug, S. ; Schlosser, P. ; Marschall, S. ; Wurst, W. ; Fuchs, H. ; Gailus-Durner, V. ; Wuttke, M. ; Hrabě de Angelis, M. ; Ćomić, J. ; Doğan, N. ; Özlük, Y. ; Taşdemir, M. ; Ağbaş, A. ; Canpolat, N. ; Orenstein, N. ; Çalışkan, S. ; Weber, R.G. ; Bergmann, C. ; Jeanpierre, C. ; Saunier, S. ; Lim, T.Y. ; Hildebrandt, F. ; Alhaddad, B. ; Basel-Salmon, L. ; Borovitz, Y. ; Wu, K. ; Antony, D. ; Matschkal, J. ; Schaaf, C.W. ; Renders, L. ; Schmaderer, C. ; Rogg, M. ; Schell, C. ; Meitinger, T. ; Heemann, U. ; Köttgen, A. ; Arnold, S.J. ; Ozaltin, F. ; Schmidts, M. ; Hoefele, J.
Implication of transcription factor FOXD2 dysfunction in syndromic congenital anomalies of the kidney and urinary tract (CAKUT).Natali, G. ; Michetti, C. ; Krawczun-Rygmaczewska, A. ; Floß, T. ; Cesca, F. ; Benfenati, F.
Conditional knockout of REST/NRSF in excitatory neurons reduces seizure susceptibility to chemical kindling.Schmidt, S. ; Stautner, C. ; Vu, D.T. ; Heinz, A. ; Regensburger, M. ; Karayel, O. ; Trümbach, D. ; Artati, A. ; Kaltenhäuser, S. ; Nassef, M.Z. ; Hembach, S. ; Steinert, L. ; Winner, B. ; Jürgen, W. ; Jastroch, M. ; Luecken, M. ; Theis, F.J. ; Westmeyer, G.G. ; Adamski, J. ; Mann, M. ; Hiller, K. ; Giesert, F. ; Vogt Weisenhorn, D.M. ; Wurst, W.
A reversible state of hypometabolism in a human cellular model of sporadic Parkinson's disease.Schmidt, H. ; Raj, T. ; O´Neill, T.J. ; Muschaweckh, A. ; Giesert, F. ; Negraschus, A. ; Höfig, K.P. ; Behrens, G. ; Esser, L. ; Baumann, Christina ; Feederle, R. ; Plaza-Sirvent, C. ; Geerlof, A. ; Gewies, A. ; Isay, S.E. ; Ruland, J. ; Schmitz, I. ; Wurst, W. ; Korn, T. ; Krappmann, D. ; Heissmeyer, V.
Unrestrained cleavage of Roquin-1 by MALT1 induces spontaneous T cell activation and the development of autoimmunity.Vetschera, P. ; Koberstein-Schwarz, B. ; Schmitt-Manderbach, T. ; Dietrich, C. ; Hellmich, W. ; Chekkoury, A. ; Symvoulidis, P. ; Reber, J. ; Westmeyer, G.G. ; López-Schier, H. ; Omar, M. ; Ntziachristos, V.
Beyond early development: Observing Zebrafish over 6 weeks with hybrid optical and optoacoustic imaging.Kahnau, P. ; Hölter, S.M. ; Voikar, V. ; Meziane, H. ; Lang, B. ; Diederich, K. ; Lewejohann, L. ; Hohlbaum, K.
A systematic review of the development and application of home cage monitoring in laboratory mice and rats.Wefers, B. ; Wurst, W. ; Kühn, R.
Gene editing in mouse zygotes using the CRISPR/Cas9 system.Buffolo, F. ; Petrosino, V. ; Albini, M. ; Moschetta, M. ; Carlini, F. ; Floß, T. ; Kerlero de Rosbo, N. ; Cesca, F. ; Rocchi, A. ; Uccelli, A. ; Benfenati, F.
Correction: Neuroinflammation induces synaptic scaling through IL-1β-mediated activation of the transcriptional repressor REST/NRSF.Stirm, M. ; Shashikadze, B. ; Blutke, A. ; Kemter, E. ; Lange, A. ; Stöckl, J.B. ; Jaudas, F. ; Laane, L. ; Kurome, M. ; Keßler, B. ; Zakhartchenko, V. ; Bähr, A. ; Klymiuk, N. ; Nagashima, H. ; Walter, M. ; Wurst, W. ; Kupatt, C. ; Fröhlich, T. ; Wolf, E.
Systemic deletion of DMD exon 51 rescues clinically severe Duchenne muscular dystrophy in a pig model lacking DMD exon 52.Gonzales García, I. ; Garcia-Clavé, E. ; Cebrian Serrano, A. ; Le Thuc, O. ; Contreras, R. ; Xu, Y. ; Gruber, T. ; Schriever, S.C. ; Legutko, B. ; Lintelmann, J. ; Adamski, J. ; Wurst, W. ; Müller, T.D. ; Woods, S.C. ; Pfluger, P.T. ; Tschöp, M.H. ; Fisette, A. ; García-Cáceres, C.
Estradiol regulates leptin sensitivity to control feeding via hypothalamic Cited1.Stroo, E. ; Janssen, L. ; Sin, O. ; Hogewerf, W. ; Koster, M. ; Harkema, L. ; Youssef, S.A. ; Beschorner, N. ; Wolters, A.H. ; Bakker, B. ; Becker, L. ; Garrett, L. ; Marschall, S. ; Hölter, S.M. ; Wurst, W. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Thathiah, A. ; Foijer, F. ; Van De Sluis, B. ; Van Deursen, J. ; Jucker, M. ; de Bruin, A. ; Nollen, E.A.
Deletion of SERF2 in mice delays embryonic development and alters amyloid deposit structure in the brain.da Silva Buttkus, P. ; Spielmann, N. ; Klein-Rodewald, T. ; Schütt, C. ; Aguilar-Pimentel, J.A. ; Amarie, O.V. ; Becker, L. ; Calzada-Wack, J. ; Garrett, L. ; Gerlini, R. ; Kraiger, M. ; Leuchtenberger, S. ; Östereicher, M.A. ; Rathkolb, B. ; Sanz-Moreno, A. ; Stoeger, C. ; Hölter, S.M. ; Seisenberger, C. ; Marschall, S. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M.
Knockout mouse models as a resource for the study of rare diseases.Jacobs, H.T. ; Szibor, M. ; Rathkolb, B. ; da Silva Buttkus, P. ; Aguilar-Pimentel, J.A. ; Amarie, O.V. ; Becker, L. ; Calzada-Wack, J. ; Dragano, N.R.V. ; Garrett, L. ; Gerlini, R. ; Hölter, S.M. ; Klein-Rodewald, T. ; Kraiger, M. ; Leuchtenberger, S. ; Marschall, S. ; Östereicher, M.A. ; Pfannes, K. ; Sanz-Moreno, A. ; Seisenberger, C. ; Spielmann, N. ; Stoeger, C. ; Wurst, W. ; Fuchs, H. ; Hrabě de Angelis, M. ; Gailus-Durner, V.
AOX delays the onset of the lethal phenotype in a mouse model of Uqcrh (complex III) disease.Calame, D.G. ; Guo, T. ; Wang, C. ; Garrett, L. ; Jolly, A. ; Dawood, M. ; Kurolap, A. ; Henig, N.Z. ; Fatih, J.M. ; Herman, I. ; Du, H. ; Mitani, T. ; Becker, L. ; Rathkolb, B. ; Gerlini, R. ; Seisenberger, C. ; Marschall, S. ; Hunter, J.V. ; Gerard, A. ; Heidlebaugh, A. ; Challman, T. ; Spillmann, R.C. ; Jhangiani, S.N. ; Coban-Akdemir, Z. ; Lalani, S. ; Liu, L. ; Revah-Politi, A. ; Iglesias, A. ; Guzman, E. ; Baugh, E. ; Boddaert, N. ; Rondeau, S. ; Ormieres, C. ; Barcia, G. ; Tan, Q.K.G. ; Thiffault, I. ; Pastinen, T. ; Sheikh, K. ; Biliciler, S. ; Mei, D. ; Melani, F. ; Shashi, V. ; Yaron, Y. ; Steele, M. ; Wakeling, E. ; Østergaard, E. ; Nazaryan-Petersen, L. ; Millan, F. ; Santiago-Sim, T. ; Thevenon, J. ; Bruel, A.L. ; Thauvin-Robinet, C. ; Popp, D. ; Platzer, K. ; Gawlinski, P. ; Wiszniewski, W. ; Marafi, D. ; Pehlivan, D. ; Posey, J.E. ; Gibbs, R.A. ; Gailus-Durner, V. ; Guerrini, R. ; Fuchs, H. ; Hrabě de Angelis, M. ; Hölter, S.M. ; Cheung, H.H. ; Gu, S. ; Lupski, J.R.
Monoallelic variation in DHX9, the gene encoding the DExH-box helicase DHX9, underlies neurodevelopment disorders and Charcot-Marie-Tooth disease.Maier, V. ; Jolicoeur, C. ; Rayburn, H. ; Takegahara, N. ; Kumanogoh, A. ; Kikutani, H. ; Tessier-Lavigne, M. ; Wurst, W. ; Friedel, R.H.
Corrigendum to Semaphorin 4C and 4G are ligands of Plexin-B2 required in cerebellar development [Mol. Cell. Neurosci., 2011 Feb;46(2):419-31].Centonze, E. ; Marte, A. ; Albini, M. ; Rocchi, A. ; Cesca, F. ; Chiacchiaretta, M. ; Floß, T. ; Baldelli, P. ; Ferroni, S. ; Benfenati, F. ; Valente, P.
Neuron-restrictive silencer factor/repressor element 1-silencing transcription factor (NRSF/REST) controls spatial K+ buffering in primary cortical astrocytes.Fosse, V. ; Oldoni, E. ; Bietrix, F. ; Budillon, A. ; Daskalopoulos, E.P. ; Fratelli, M. ; Gerlach, B. ; Groenen, P.M.A. ; Hölter, S.M. ; Menon, J.M.L. ; Mobasheri, A. ; Osborne, N. ; Ritskes-Hoitinga, M. ; Ryll, B. ; Schmitt, E. ; Ussi, A. ; Andreu, A.L. ; McCormack, E. ; PERMIT group
Recommendations for robust and reproducible preclinical research in personalised medicine.Muffels, I.J.J. ; Schene, I.F. ; Rehmann, H. ; Massink, M.P.G. ; van der Wal, M.M. ; Bauder, C. ; Labeur, M. ; Armando, N.G. ; Lequin, M.H. ; Houben, M.L. ; Giltay, J.C. ; Haitjema, S. ; Huisman, A. ; Vansenne, F. ; Bluvstein, J. ; Pappas, J. ; Shailee, L.V. ; Zarate, Y.A. ; Mokry, M. ; van Haaften, G.W. ; Nieuwenhuis, E.E.S. ; Refojo, D. ; van Wijk, F. ; Fuchs, S.A. ; van Hasselt, P.M.
Bi-allelic variants in NAE1 cause intellectual disability, ischiopubic hypoplasia, stress-mediated lymphopenia and neurodegeneration.Vetrivel, S. ; Truong, D.J.J. ; Wurst, W. ; Graw, J. ; Giesert, F.
Identification of ocular regulatory functions of core histone variant H3.2.Hölter, S.M. ; Wells, S. ; Voikar, V.
Improving biomedical research by automated behaviour monitoring in the animal home cage - action needed for networking.Spielmann, N. ; Miller, G. ; Oprea, T.I. ; Hsu, C.W. ; Fobo, G. ; Frishman, G. ; Montrone, C. ; Haseli Mashhadi, H. ; Mason, J. ; Munoz Fuentes, V. ; Leuchtenberger, S. ; Ruepp, A. ; Wagner, M. ; Westphal, D.S. ; Wolf, C. ; Görlach, A. ; Sanz-Moreno, A. ; Cho, Y.-L. ; Teperino, R. ; Brandmaier, S. ; Sharma, S. ; Galter, I. ; Östereicher, M.A. ; Zapf, L. ; Mayer-Kuckuk, P. ; Rozman, J. ; Teboul, L. ; Bunton-Stasyshyn, R.K.A. ; Cater, H. ; Stewart, M. ; Christou, S. ; Westerberg, H. ; Willett, A.M. ; Wotton, J.M. ; Roper, W.B. ; Christiansen, A.E. ; Ward, C.S. ; Heaney, J.D. ; Reynolds, C.L. ; Prochazka, J. ; Bower, L. ; Clary, D. ; Selloum, M. ; Bou About, G. ; Wendling, O. ; Jacobs, H. ; Leblanc, S. ; Meziane, H. ; Sorg, T. ; Audain, E. ; Gilly, A. ; Rayner, N.W. ; Aguilar-Pimentel, J.A. ; Becker, L. ; Garrett, L. ; Hölter, S.M. ; Amarie, O.V. ; Calzada-Wack, J. ; Klein-Rodewald, T. ; da Silva Buttkus, P. ; Lengger, C. ; Stoeger, C. ; Gerlini, R. ; Rathkolb, B. ; Mayr, D. ; Seavitt, J. ; Gaspero, A. ; Green, J.R. ; Garza, A. ; Bohat, R. ; Wong, L. ; McElwee, M.L. ; Kalaga, S. ; Rasmussen, T.L. ; Lorenzo, I. ; Lanza, D.G. ; Samaco, R.C. ; Veeraragaven, S. ; Gallegos, J.J. ; Kasparek, P. ; Petrezselyova, S. ; King, R. ; Johnson, S. ; Cleak, J. ; Szkoe-Kovacs, Z. ; Codner, G.F. ; Mackenzie, M. ; Caulder, A. ; Kenyon, J. ; Gardiner, W. ; Phelps, H. ; Hancock, R. ; Norris, C.M. ; Moore, M.A. ; Seluke, A.M. ; Urban, R. ; Kane, C. ; Goodwin, L.O. ; Peterson, K.A. ; Mckay, M.
Publisher Correction: Extensive identification of genes involved in congenital and structural heart disorders and cardiomyopathy (Nature Cardiovascular Research, (2022), 1, 2, (157-173), 10.1038/s44161-022-00018-8).Dening, Y. ; Straßl, T. ; Ruf, V. ; Dirscherl, P. ; Chovsepian, A. ; Stievenard, A. ; Khairnar, A. ; Schmidt, F. ; Giesert, F. ; Herms, J. ; Levin, J. ; Dieterich, M. ; Falkai, P. ; Weisenhorn, D.M. ; Wurst, W. ; Giese, A. ; Pan-Montojo, F.
Toxicity of extracellular alpha-synuclein is independent of intracellular alpha-synuclein.Garrett, L. ; Trümbach, D. ; Spielmann, N. ; Wurst, W. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Hölter, S.M.
A rationale for considering heart/brain axis control in neuropsychiatric disease.Seibt, T. ; Wahida, A. ; Mishima, E. ; Conrad, M.
Den „Eisen-Tod“ verhindern Bedeutung der antioxidativen Vitamine und der Vitamin-K-Familie.Klein-Rodewald, T. ; Micklich, K. ; Sanz-Moreno, A. ; Tost, M. ; Calzada-Wack, J. ; Adler, T. ; Klaften, M. ; Sabrautzki, S. ; Aigner, B. ; Kraiger, M. ; Gailus-Durner, V. ; Fuchs, H. ; German Mouse Clinic Consortium (Aguilar-Pimentel, J.A. ; Becker, L. ; Garrett, L. ; Hölter, S.M. ; Prehn, C. ; Rácz, I. ; Rozman, J. ; Puk, O. ; Schrewe, A. ; Adamski, J. ; Esposito, I. ; Wurst, W. ; Stoeger, C.) ; Gründer, A. ; Pahl, H. ; Wolf, E. ; Hrabě de Angelis, M. ; Rathkolb, B.
New C3H KitN824K/WT cancer mouse model develops late-onset malignant mammary tumors with high penetrance.Xie, K. ; Fuchs, H. ; Scifo, E. ; Liu, D. ; Aziz, A. ; Aguilar-Pimentel, J.A. ; Amarie, O.V. ; Becker, L. ; da Silva Buttkus, P. ; Calzada-Wack, J. ; Cho, Y.-L. ; Deng, Y. ; Edwards, A.C. ; Garrett, L. ; Georgopoulou, C. ; Gerlini, R. ; Hölter, S.M. ; Klein-Rodewald, T. ; Kramer, M. ; Leuchtenberger, S. ; Lountzi, D. ; Mayer-Kuckuk, P. ; Nover, L.L. ; Oestereicher, M.A. ; Overkott, C. ; Pearson, B.L. ; Rathkolb, B. ; Rozman, J. ; Russ, J. ; Schaaf, K. ; Spielmann, N. ; Sanz-Moreno, A. ; Stoeger, C. ; Treise, I. ; Bano, D. ; Busch, D.H. ; Graw, J. ; Klingenspor, M. ; Klopstock, T. ; Mock, B.A. ; Salomoni, P. ; Schmidt-Weber, C.B. ; Weiergräber, M. ; Wolf, E. ; Wurst, W. ; Gailus-Durner, V. ; Breteler, M.M.B. ; Hrabě de Angelis, M. ; Ehninger, D.
Deep phenotyping and lifetime trajectories reveal limited effects of longevity regulators on the aging process in C57BL/6J mice.Stafford, C.A. ; Gassauer, A.M. ; de Oliveira Mann, C.C. ; Tanzer, M.C. ; Fessler, E. ; Wefers, B. ; Nagl, D. ; Kuut, G. ; Sulek, K. ; Vasilopoulou, C.G. ; Schwojer, S.J. ; Wiest, A. ; Pfautsch, M.K. ; Wurst, W. ; Yabal, M. ; Fröhlich, T. ; Mann, M. ; Gisch, N. ; Jae, L.T. ; Hornung, V.
Phosphorylation of muramyl peptides by NAGK is required for NOD2 activation.Cater, M. ; Hölter, S.M.
A pathophysiological intersection of diabetes and alzheimer's disease.Maity-Kumar, G. ; Ständer, L. ; de Angelis, M. ; Lee, S. ; Molenaar, A. ; Becker, L. ; Garrett, L. ; Amarie, O.V. ; Hölter, S.M. ; Wurst, W. ; Fuchs, H. ; Feuchtinger, A. ; Gailus-Durner, V. ; García-Cáceres, C. ; Othman, A.E. ; Brockmann, C. ; Schöffling, V.I. ; Beiser, K. ; Krude, H. ; Mroz, P.A. ; Hofmann, S.M. ; Tuckermann, J. ; DiMarchi, R.D. ; Hrabě de Angelis, M. ; Tschöp, M.H. ; Pfluger, P.T. ; Müller, T.D.
Validation of Mct8/Oatp1c1 dKO mice as a model organism for the Allan-Herndon-Dudley Syndrome.Kandaswamy, S. ; Zobel, L. ; John, B. ; Santhiya, S.T. ; Bogedein, J. ; Przemeck, G.K.H. ; Gailus-Durner, V. ; Fuchs, H. ; Biel, M. ; Hrabě de Angelis, M. ; Graw, J. ; Michalakis, S. ; Amarie, O.V.
Mutations within the cGMP-binding domain of CNGA1 causing autosomal recessive retinitis pigmentosa in human and animal model.Schweizer, U. ; Wirth, E.K. ; Klopstock, T. ; Hölter, S.M. ; Becker, L. ; Moskovitz, J. ; Grune, T. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Köhrle, J. ; Schomburg, L.
Seizures, ataxia and parvalbumin-expressing interneurons respond to selenium supply in Selenop-deficient mice.Stirm, M. ; Fonteyne, L.M. ; Shashikadze, B. ; Stöckl, J.B. ; Kurome, M. ; Keßler, B. ; Zakhartchenko, V. ; Kemter, E. ; Blum, H. ; Arnold, G.J. ; Matiasek, K. ; Wanke, R. ; Wurst, W. ; Nagashima, H. ; Knieling, F. ; Walter, M.C. ; Kupatt, C. ; Fröhlich, T. ; Klymiuk, N. ; Blutke, A. ; Wolf, E.
Pig models for Duchenne muscular dystrophy - from disease mechanisms to validation of new diagnostic and therapeutic concepts.Schmidt, S. ; Luecken, M. ; Trümbach, D. ; Hembach, S. ; Niedermeier, K.M. ; Wenck, N. ; Pflügler, K. ; Stautner, C. ; Böttcher, A. ; Lickert, H. ; Ramirez Suastegui, C. ; Ahmad, R. ; Ziller, M.J. ; Fitzgerald, J.C. ; Ruf, V. ; van de Berg, W.D.J. ; Jonker, A.J. ; Gasser, T. ; Winner, B. ; Winkler, J. ; Weisenhorn, D.M. ; Giesert, F. ; Theis, F.J. ; Wurst, W.
Primary cilia and SHH signaling impairments in human and mouse models of Parkinson's disease.Spielmann, N. ; Miller, G. ; Oprea, T.I. ; Hsu, C.-W. ; Fobo, G. ; Frishman, G. ; Montrone, C. ; Hasel Mashhadi, H. ; Mason, J. ; Munoz Fuentes, V. ; Leuchtenberger, S. ; Ruepp, A. ; Wagner, M. ; Westphal, D.S. ; Wolf, C. ; Görlach, A. ; Sanz-Moreno, A. ; Cho, Y.-L. ; Teperino, R. ; Brandmaier, S. ; Sharma, S. ; Galter, I. ; Östereicher, M.A. ; Zapf, L. ; Mayer-Kuckuk, P. ; Rozman, J. ; Teboul, L. ; Bunton, R.K.A. ; Cater, H. ; Stewart, M. ; Christou, S. ; Westerberg, H. ; Willet, A.M. ; Wotton, J.M. ; Roper, W.B. ; Christiansen, A.E. ; Ward, C.S. ; Heaney, J.D. ; Reynolds, C.L. ; Prochazka, J. ; Bower, L. ; Clary, D. ; Selloum, M. ; Bou About, G. ; Wendling, O. ; Jacobs, H. ; Leblanc, S. ; Meziane, H. ; Sorg, T. ; Audain, E. ; Gilly, A. ; Rayner, N.W. ; Hitz, M.-P. ; Zeggini, E. ; Wolf, E. ; Sedlacek, R. ; Murray, S.A. ; Svenson, K.L. ; Braun, R.E. ; White, J.K. ; Kelsey, L. ; Gao, X. ; Shiroishi, T. ; Xu, Y. ; Seong, J.K. ; Mammano, F. ; Tocchini-Valentini, G.P. ; Beaudet, A.L. ; Meehan, T.F. ; Parkinson, H. ; Smedley, D. ; Mallon, A.-M. ; Wells, S.E. ; Grallert, H. ; Wurst, W. ; Marschall, S. ; Fuchs, H. ; Brown, S.D.M. ; Flenniken, A.M. ; Nutter, L.M.J. ; McKerlie, C. ; Herault, Y. ; Lloyd, K.C.K. ; Dickinson, M.E. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; IMPC Consortium (Aguilar-Pimentel, J.A. ; Becker, L. ; Garrett, L. ; Hölter, S.M. ; Amarie, O.V. ; Calzada-Wack, J. ; Klein-Rodewald, T. ; Lengger, C. ; Stoeger, C. ; Gerlini, R. ; Rathkolb, B. ; Seisenberger, C. ; Bürger, A. ; Giesert, F.)
Extensive identification of genes involved in congenital and structural heart disorders and cardiomyopathy.Danileviciute, E. ; Zeng, N. ; Capelle, C.M. ; Paczia, N. ; Gillespie, M.A. ; Kurniawan, H. ; Benzarti, M. ; Merz, M.P. ; Coowar, D. ; Fritah, S. ; Vogt Weisenhorn, D.M. ; Gomez Giro, G. ; Grusdat, M. ; Baron, A. ; Guerin, C. ; Franchina, D.G. ; Leonard, C. ; Domingues, O. ; Delhalle, S. ; Wurst, W. ; Turner, J.D. ; Schwamborn, J.C. ; Meiser, J. ; Krüger, R. ; Ranish, J. ; Brenner, D. ; Linster, C.L. ; Balling, R. ; Ollert, M. ; Hefeng, F.Q.
PARK7/DJ-1 promotes pyruvate dehydrogenase activity and maintains Treg homeostasis during ageing.Sanchez-Gonzalez, R. ; Koupourtidou, C. ; Lepko, T. ; Zambusi, A. ; Novoselc, K.T. ; Durovic, T. ; Aschenbroich, S. ; Schwarz, V. ; Breunig, C. ; Straka, H. ; Huttner, H.B. ; Irmler, M. ; Beckers, J. ; Wurst, W. ; Zwergal, A. ; Schauer, T. ; Straub, T. ; Czopka, T. ; Trümbach, D. ; Götz, M. ; Stricker, S.H. ; Ninkovic, J.
Innate immune pathways promote oligodendrocyte progenitor cell recruitment to the injury site in adult Zebrafish brain.Falkai, P. ; Koutsouleris, N. ; Bertsch, K. ; Bialas, M. ; Binder, E. ; Bühner, M. ; Buyx, A. ; Cai, N. ; Cappello, S. ; Ehring, T. ; Gensichen, J. ; Hamann, J. ; Hasan, A. ; Henningsen, P. ; Leucht, S. ; Möhrmann, K.H. ; Nagelstutz, E. ; Padberg, F. ; Peters, A. ; Pfäffel, L. ; Reich-Erkelenz, D. ; Riedl, V. ; Rueckert, D. ; Schmitt, A. ; Schulte-Körne, G. ; Scheuring, E. ; Schulze, T.G. ; Starzengruber, R. ; Stier, S. ; Theis, F.J. ; Winkelmann, J. ; Wurst, W. ; Priller, J.
Concept of the Munich/Augsburg Consortium Precision in Mental Health for the German Center of Mental Health.Giehrl-Schwab, J. ; Giesert, F. ; Rauser, B. ; Lao, C.L. ; Hembach, S. ; Lefort, S. ; Ibarra Del Rio, I.A. ; Koupourtidou, C. ; Luecken, M. ; Truong, D.J.J. ; Fischer-Sternjak, J. ; Masserdotti, G. ; Prakash, N. ; Ninkovic, J. ; Hölter, S.M. ; Vogt Weisenhorn, D.M. ; Theis, F.J. ; Götz, M. ; Wurst, W.
Parkinson's disease motor symptoms rescue by CRISPRa-reprogramming astrocytes into GABAergic neurons.Schmidt, S. ; Vogt Weisenhorn, D.M. ; Wurst, W.
Chapter 5 – “Parkinson's disease – A role of non-enzymatic posttranslational modifications in disease onset and progression?”.Eumorphia Consortium (Hrabě de Angelis, M. ; Wurst, W. ; Abe, K. ; Beckers, J. ; Busch, D.H. ; Dalke, C. ; Gailus-Durner, V. ; Fuchs, H. ; Graw, J. ; Hölter, S.M. ; Kallnik, M. ; Lengger, C. ; Pedersen, V. ; Puk, O. ; Vogt Weisenhorn, D.M. ; Wagner, S.) ; Quintanilla-Fend, L.
EMPReSS: Standardized phenotype screens for functional annotation of the mouse genome (vol 37, pg 1155, 2005).Ainsbury, E.A. ; Dalke, C. ; Mancuso, M. ; Kadhim, M. ; Quinlan, R.A. ; Azizova, T. ; Dauer, L.T. ; Dynlacht, J.R. ; Tanner, R. ; Hamada, N.
Introduction to the special LDLensRad focus issue.Garrett, L. ; da Silva Buttkus, P. ; Rathkolb, B. ; Gerlini, R. ; Becker, L. ; Sanz-Moreno, A. ; Seisenberger, C. ; Zimprich, A. ; Aguilar-Pimentel, J.A. ; Amarie, O.V. ; Cho, Y.-L. ; Kraiger, M. ; Spielmann, N. ; Calzada-Wack, J. ; Marschall, S. ; Busch, D. ; Schmidt-Weber, C.B. ; Wolf, E. ; Wurst, W. ; Fuchs, H. ; Gailus-Durner, V. ; Hölter, S.M. ; Hrabě de Angelis, M.
Post-synaptic scaffold protein TANC2 in psychiatric and somatic disease risk.Dieckmann, S. ; Strohmeyer, A. ; Willershäuser, M. ; Maurer, S.F. ; Wurst, W. ; Marschall, S. ; Hrabě de Angelis, M. ; Kühn, R. ; Worthmann, A. ; Fuh, M.M. ; Heeren, J. ; Pauling, J.K. ; Klingenspor, M.
Susceptibility to diet-induced obesity at thermoneutral conditions is independent of UCP1.Garrett, L. ; Ung, M.-C. ; Einicke, J. ; Zimprich, A. ; Fenzl, F. ; Pawliczek, D. ; Graw, J. ; Dalke, C. ; Hölter, S.M.
Complex long-term effects of radiation on adult mouse behaviour.Clemen, C.S. ; Schmidt, A. ; Winter, L. ; Canneva, F. ; Wittig, I. ; Becker, L. ; Coras, R. ; Berwanger, C. ; Hofmann, A. ; Eggers, B. ; Marcus, K. ; Gailus-Durner, V. ; Fuchs, H. ; Hrabě de Angelis, M. ; Krüger, M. ; von Hörsten, S. ; Eichinger, L. ; Schröder, R. ; German Mouse Clinic Consortium (Aguilar-Pimentel, J.A. ; Schmidt-Weber, C.B. ; Treise, I. ; Spielmann, N. ; Amarie, O.V. ; Rozman, J. ; Garrett, L. ; Hölter, S.M. ; Wurst, W. ; Calzada-Wack, J. ; da Silva Buttkus, P. ; Rathkolb, B. ; Östereicher, M.A. ; Leuchtenberger, S. ; Stoeger, C.) ; Maier, H.
N471D WASH complex subunit strumpellin knock-in mice display mild motor and cardiac abnormalities and BPTF and KLHL11 dysregulation in brain tissue.McCarron, R.A. ; Barnard, S.G.R. ; Babini, G. ; Dalke, C. ; Graw, J. ; Leonardi, S. ; Mancuso, M. ; Moquet, J.E. ; Pawliczek, D. ; Pazzaglia, S. ; De Stefano, I. ; Ainsbury, E.A.
Radiation-induced lens opacity and cataractogenesis: A lifetime study using mice of varying genetic backgrounds.Pawliczek, D. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Quinlan, R. ; Graw, J. ; Dalke, C.
On the nature of murine radiation-induced subcapsular cataracts: Optical coherence tomography-based fine classification, in vivo dynamics and impact on visual acuity.Pawliczek, D.
Schädigung des optischen Apparats von Mus musculus nach Exposition gegenüber ionisierender Strahlung moderater Dosis: In-vivo- und post-mortem-Analyse der Linse, Retina und Cornea.Behrens, G. ; Edelmann, S.L. ; Raj, T. ; Kronbeck, N. ; Monecke, T. ; Davydova, E.-O. ; Wong, E.H. ; Kifinger, L. ; Giesert, F. ; Kirmaier, M.E. ; Hohn, C. ; de Jonge, L.S. ; Pisfil, M.G. ; Fu, M. ; Theurich, S. ; Feske, S. ; Kawakami, N. ; Wurst, W. ; Niessing, D. ; Heissmeyer, V.
Disrupting Roquin-1 interaction with Regnase-1 induces autoimmunity and enhances antitumor responses.O'Neill, T.J. ; Seeholzer, T. ; Gewies, A. ; Gehring, T. ; Giesert, F. ; Hamp, I. ; Grass, C. ; Schmidt, H. ; Kriegsmann, K. ; Tofaute, M.J. ; Demski, K. ; Poth, T. ; Rosenbaum, M. ; Schnalzger, T. ; Ruland, J. ; Göttlicher, M. ; Kriegsmann, M. ; Naumann, R. ; Heissmeyer, V. ; Wurst, W. ; Krappmann, D.
TRAF6 prevents fatal inflammation by homeostatic suppression of MALT1 protease.Vidali, S. ; Gerlini, R. ; Thompson, K. ; Urquhart, J.E. ; Meisterknecht, J. ; Aguilar-Pimentel, J.A. ; Amarie, O.V. ; Becker, L. ; Breen, C. ; Calzada-Wack, J. ; Chhabra, N.F. ; Cho, Y.-L. ; da Silva Buttkus, P. ; Feichtinger, R.G. ; Gampe, K. ; Garrett, L. ; Höfig, K.P. ; Hölter, S.M. ; Jameson, E. ; Klein-Rodewald, T. ; Leuchtenberger, S. ; Marschall, S. ; Mayer-Kuckuk, P. ; Miller, G. ; Oestereicher, M.A. ; Pfannes, K. ; Rathkolb, B. ; Rozman, J. ; Sanders, C. ; Spielmann, N. ; Stoeger, C. ; Szibor, M. ; Treise, I. ; Walter, J.H. ; Wurst, W. ; Mayr, J.A. ; Fuchs, H. ; Gärtner, U. ; Wittig, I. ; Taylor, R.W. ; Newman, W.G. ; Prokisch, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M.
Characterising a homozygous two-exon deletion in UQCRH: Comparing human and mouse phenotypes.Strauß, T. ; Marvian-Tayaranian, A. ; Sadikoglou, E. ; Dhingra, A. ; Wegner, F. ; Trümbach, D. ; Wurst, W. ; Heutink, P. ; Schwarz, S.C. ; Höglinger, G.U.
iPS cell-based model for MAPT Haplotype as a risk factor for human tauopathies identifies no major differences in TAU expression.Nagler, J. ; Schriever, S.C. ; Romanov, A. ; Weisenhorn, D.M. ; Wurst, W. ; Pfluger, P.T. ; Schramm, K.-W.
Determination of morphine and norlaudanosoline in murine brain regions by dispersive liquid-liquid micro-extraction and liquid chromatograpy-electrochemical detection.Ung, M.-C.
The long-term effects of low dose ionizing radiation on the adult mouse brain and the consequences for behavior.Rocchi, A. ; Carminati, E. ; De Fusco, A. ; Kowalska, J.A. ; Floß, T. ; Benfenati, F.
REST/NRSF deficiency impairs autophagy and leads to cellular senescence in neurons.Hsia, H.E. ; Tüshaus, J. ; Feng, X. ; Hofmann, L.I. ; Wefers, B. ; Marciano, D.K. ; Wurst, W. ; Lichtenthaler, S.F.
Endoglycan (PODXL2) is proteolytically processed by ADAM10 (a disintegrin and metalloprotease 10) and controls neurite branching in primary neurons.Truong, D.J.J. ; Phlairaharn, T. ; Eßwein, B. ; Gruber, C. ; Tümen, D. ; Baligács, E. ; Armbrust, N. ; Vaccaro, F.L. ; Lederer, E.-M. ; Beck, E.M. ; Geilenkeuser, J. ; Göppert, S. ; Krumwiede, L. ; Grätz, C. ; Raffl, G. ; Schwarz, D. ; Zirngibl, M. ; Živanić, M. ; Beyer, M. ; Körner, J.D. ; Santl, T. ; Evsyukov, V. ; Strauß, T. ; Schwarz, S.C. ; Höglinger, G.U. ; Heutink, P. ; Doll, S. ; Conrad, M. ; Giesert, F. ; Wurst, W. ; Westmeyer, G.G.
Non-invasive and high-throughput interrogation of exon-specific isoform expression.Bespalov, A. ; Bernard, R. ; Gilis, A. ; Gerlach, B. ; Guillen, J. ; Castagne, V. ; Lefevre, I. ; Ducrey, F. ; Monk, L. ; Bongiovanni, S. ; Altevogt, B. ; Arroyo Araujo, M. ; Bikovski, L. ; de Bruin, N. ; Castanos-Velez, E. ; Dityatev, A. ; Emmerich, C.H. ; Fares, R. ; Ferland-Beckham, C. ; Froger-Colléaux, C. ; Gailus-Durner, V. ; Hölter, S.M. ; Hofmann, M.C. ; Kabitzke, P. ; Kas, M.J.H. ; Kurreck, C. ; Moser, P. ; Pietraszek, M. ; Popik, P. ; Potschka, H. ; Prado Montes de Oca, E. ; Restivo, L. ; Riedel, G. ; Ritskes-Hoitinga, M. ; Samardzic, J. ; Schunn, M. ; Stoeger, C. ; Voikar, V. ; Vollert, J. ; Wever, K.E. ; Wuyts, K. ; MacLeod, M.R. ; Dirnagl, U. ; Steckler, T.
Introduction to the EQIPD quality system.Eberherr, A.C. ; Maaske, A. ; Wolf, C. ; Giesert, F. ; Berutti, R. ; Rusha, E. ; Pertek, A. ; Kastlmeier, M.T. ; Voss, C. ; Plummer, M. ; Sayed, A. ; Graf, E. ; Effner, R. ; Volz, T. ; Drukker, M. ; Strom, T.M. ; Meitinger, T. ; Stöger, T. ; Buyx, A.M. ; Hagl, B. ; Renner, E.D.
Rescue of STAT3 function in hyper-IgE syndrome using adenine base editing.Biagosch, C. ; Vidali, S. ; Faerberboeck, M. ; Hensler, S. ; Becker, L. ; Amarie, O.V. ; Aguilar-Pimentel, J.A. ; Garrett, L. ; Klein-Rodewald, T. ; Rathkolb, B. ; Zanuttigh, E. ; Calzada-Wack, J. ; da Silva Buttkus, P. ; Rozman, J. ; Treise, I. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Janik, D. ; Wurst, W. ; Mayr, J.A. ; Klopstock, T. ; Meitinger, T. ; Prokisch, H. ; Iuso, A.
A comprehensive phenotypic characterization of a whole-body Wdr45 knock-out mouse.Schänzer, A. ; Achleitner, M. ; Trümbach, D. ; Hubert, L. ; Munnich, A. ; Ahlemeyer, B. ; AlAbdulrahim, M.M. ; Greif, P.A. ; Vosberg, S. ; Hummer, B. ; Feichtinger, R.G. ; Mayr, J.A. ; Wortmann, S.B. ; Aichner, H. ; Rudnik-Schöneborn, S. ; Ruiz, A. ; Gabau, E. ; Sánchez, J.P. ; Ellard, S. ; Homfray, T. ; Stals, K.L. ; Wurst, W. ; Neubauer, B.A. ; Acker, T. ; Bohlander, S.K. ; Asensio, C. ; Besmond, C. ; Alkuraya, F.S. ; AlSayed, M.D. ; Hahn, A. ; Weber, A.
Mutations in HID1 cause syndromic infantile encephalopathy and hypopituitarism.Buffolo, F. ; Petrosino, V. ; Albini, M. ; Moschetta, M. ; Carlini, F. ; Floß, T. ; Kerlero de Rosbo, N. ; Cesca, F. ; Rocchi, A. ; Uccelli, A. ; Benfenati, F.
Neuroinflammation induces synaptic scaling through IL-1β-mediated activation of the transcriptional repressor REST/NRSF.Conlon, T.M. ; John-Schuster, G. ; Heide, D. ; Pfister, D. ; Lehmann, M. ; Hu, Y. ; Ertüz, Z. ; López, M.A. ; Ansari, M. ; Strunz, M. ; Mayr, C. ; Angelidis, I. ; Ciminieri, C. ; Costa, R. ; Kohlhepp, M.S. ; Guillot, A. ; Güneş, G. ; Jeridi, A. ; Funk, M.C. ; Beroshvili, G. ; Prokosch, S. ; Hetzer, J. ; Verleden, S.E. ; Alsafadi, H.N. ; Lindner, M. ; Burgstaller, G. ; Becker, L. ; Irmler, M. ; Dudek, M. ; Janzen, J. ; Goffin, E. ; Gosens, R. ; Knolle, P. ; Pirotte, B. ; Stöger, T. ; Beckers, J. ; Wagner, D.E. ; Singh, I. ; Theis, F.J. ; Hrabě de Angelis, M. ; O’Connor, T. ; Tacke, F. ; Boutros, M. ; Dejardin, E. ; Eickelberg, O. ; Schiller, H. B. ; Königshoff, M. ; Heikenwalder, M. ; Yildirim, A.Ö.
Publisher Correction: Inhibition of LTβR signalling activates WNT-induced regeneration in lung (Nature, (2020), 588, 7836, (151-156), 10.1038/s41586-020-2882-8).Weisheit, I. ; Kroeger, J.A. ; Malik, R. ; Wefers, B. ; Lichtner, P. ; Wurst, W. ; Dichgans, M. ; Paquet, D.
Simple and reliable detection of CRISPR-induced on-target effects by qgPCR and SNP genotyping.Hansen, J. ; von Melchner, H. ; Wurst, W.
Mutant non-coding RNA resource in mouse embryonic stem cells.Findeiss, E. ; Schwarz, S.C. ; Evsyukov, V. ; Roesler, T.W. ; Hoellerhage, M. ; Chakroun, T. ; Nykaenen, N. ; Shen, Y. ; Wurst, W. ; Kohl, M. ; Tost, J. ; Hoeglinger, G.U.
Comprehensive miRNome-wide profiling in a neuronal cell model of synucleinopathy implies involvement of cell cycle genes.Birling, M.C. ; Yoshiki, A. ; Adams, D.J. ; Ayabe, S. ; Beaudet, A.L. ; Bottomley, J. ; Bradley, A. ; Brown, S.D.M. ; Bürger, A. ; Bushell, W. ; Chiani, F. ; Chin, H.G. ; Christou, S. ; Codner, G.F. ; DeMayo, F.J. ; Dickinson, M.E. ; Doe, B. ; Donahue, L.R. ; Fray, M.D. ; Gambadoro, A. ; Gao, X. ; Gertsenstein, M. ; Gomez-Segura, A. ; Goodwin, L.O. ; Heaney, J.D. ; Hérault, Y. ; Hrabě de Angelis, M. ; Jiang, S.T. ; Justice, M.J. ; Kasparek, P. ; King, R.E. ; Kühn, R. ; Lee, H. ; Lee, Y.J. ; Liu, Z. ; Lloyd, K.C.K. ; Lorenzo, I. ; Mallon, A.M. ; McKerlie, C. ; Meehan, T.F. ; Fuentes, V.M. ; Newman, S. ; Nutter, L.M.J. ; Oh, G.T. ; Pavlovic, G. ; Ramirez-Solis, R. ; Rosen, B. ; Ryder, E.J. ; Santos, L.A. ; Schick, J. ; Seavitt, J.R. ; Sedlacek, R. ; Seisenberger, C. ; Seong, J.K. ; Skarnes, W.C. ; Sorg, T. ; Steel, K.P. ; Tamura, M. ; Tocchini-Valentini, G.P. ; Wang, C.L. ; Wardle-Jones, H. ; Wattenhofer-Donzé, M. ; Wells, S. ; Wiles, M.V. ; Willis, B.J. ; Wood, J.A. ; Wurst, W. ; Xu, Y. ; Teboul, L. ; Murray, S.A. ; IMPC Consortium (Gailus-Durner, V. ; Fuchs, H. ; Marschall, S.)
A resource of targeted mutant mouse lines for 5,061 genes.Kupatt, C. ; Windisch, A. ; Moretti, A. ; Wolf, E. ; Wurst, W. ; Walter, M.C.
Genome editing for Duchenne muscular dystrophy: A glimpse of the future?Brandes, R.P. ; Dueck, A. ; Engelhardt, S. ; Kaulich, M. ; Kupatt, C. ; De Angelis, M.T. ; Leisegang, M.S. ; le Noble, F. ; Moretti, A. ; Müller, O.J. ; Skryabin, B.V. ; Thum, T. ; Wurst, W.
DGK and DZHK position paper on genome editing: Basic science applications and future perspective.Ruiz Ojeda, F.J. ; Wang, J. ; Bäcker, T. ; Krueger, M. ; Zamani, S. ; Rosowski, S. ; Gruber, T. ; Onogi, Y. ; Feuchtinger, A. ; Schulz, T.J. ; Fässler, R. ; Müller, T.D. ; García-Cáceres, C. ; Meier, M. ; Blüher, M. ; Ussar, S.
Active integrins regulate white adipose tissue insulin sensitivity and brown fat thermogenesis.Pawliczek, D. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Graw, J. ; Dalke, C.
Ionising radiation causes vision impairment in neonatal B6C3F1 mice.Kunze, S. ; Cecil, A. ; Prehn, C. ; Möller, G. ; Ohlmann, A. ; Wildner, G. ; Thurau, S. ; Unger, K. ; Rößler, U. ; Hölter, S.M. ; Tapio, S. ; Wagner, F. ; Beyerlein, A. ; Theis, F.J. ; Zitzelsberger, H. ; Kulka, U. ; Adamski, J. ; Graw, J. ; Dalke, C.
Posterior subcapsular cataracts are a late effect after acute exposure to 0.5 Gy ionizing radiation in mice.Frey, L. ; Ziętara, N. ; Lyszkiewicz, M. ; Marquardt, B. ; Mizoguchi, Y. ; Linder, M.I. ; Liu, Y. ; Giesert, F. ; Wurst, W. ; Dahlhoff, M. ; Schneider, M. ; Wolf, E. ; Somech, R. ; Klein, C.
Mammalian VPS45 orchestrates trafficking through the endosomal system.Schmid, P.W.N. ; Lim, N.C.H. ; Peters, C. ; Back, K.C. ; Bourgeois, B. ; Pirolt, F. ; Richter, B. ; Peschek, J. ; Puk, O. ; Amarie, O.V. ; Dalke, C. ; Haslbeck, M. ; Weinkauf, S. ; Madl, T. ; Graw, J. ; Buchner, J.
Imbalances in the eye lens proteome are linked to cataract formation.Swan, A.L. ; Schütt, C. ; Rozman, J. ; Del Mar Muñiz Moreno, M. ; Brandmaier, S. ; Simon, M. ; Leuchtenberger, S. ; Griffiths, M. ; Brommage, R. ; Keskivali-Bond, P. ; Grallert, H. ; Werner, T. ; Teperino, R. ; Becker, L. ; Miller, G. ; Moshiri, A. ; Seavitt, J.R. ; Cissell, D.D. ; Meehan, T.F. ; Acar, E.F. ; Lelliott, C.J. ; Flenniken, A.M. ; Champy, M.F. ; Sorg, T. ; Ayadi, A. ; Braun, R.E. ; Cater, H. ; Dickinson, M.E. ; Flicek, P. ; Gallegos, J. ; Ghirardello, E.J. ; Heaney, J.D. ; Jacquot, S. ; Lally, C. ; Logan, J.G. ; Teboul, L. ; Mason, J. ; Spielmann, N. ; McKerlie, C. ; Murray, S.A. ; Nutter, L.M.J. ; Odfalk, K.F. ; Parkinson, H. ; Prochazka, J. ; Reynolds, C.L. ; Selloum, M. ; Spoutil, F. ; Svenson, K.L. ; Vales, T.S. ; Wells, S.E. ; White, J.K. ; Sedlacek, R. ; Wurst, W. ; Lloyd, K.K.C. ; Croucher, P.I. ; Fuchs, H. ; Williams, G.R. ; Bassett, D. ; Gailus-Durner, V. ; Herault, Y. ; Mallon, A.M. ; Brown, S.D.M. ; Mayer-Kuckuk, P. ; Hrabě de Angelis, M. ; IMPC Consortium (Aguilar-Pimentel, J.A. ; Amarie, O.V. ; Bürger, A. ; Calzada-Wack, J. ; Cho, Y.-L. ; Giesert, F. ; Garrett, L. ; Graw, J. ; Hörlein, A. ; Hölter, S.M. ; Klein-Rodewald, T. ; Kühn, R. ; Lengger, C. ; Marschall, S. ; Rathkolb, B. ; Sanz-Moreno, A. ; Seisenberger, C. ; Steinkamp, R. ; Stoeger, C. ; Treise, I. ; Zimprich, A.) ; Beckers, J.
Mouse mutant phenotyping at scale reveals novel genes controlling bone mineral density.Ainsbury, E.A. ; Dalke, C. ; Hamada, N. ; Benadjaoud, M.A. ; Chumak, V. ; Ginjaume, M. ; Kok, J.L. ; Mancuso, M. ; Sabatier, L. ; Struelens, L. ; Thariat, J. ; Jourdain, J.R.
Radiation-induced lens opacities: Epidemiological, clinical and experimental evidence, methodological issues, research gaps and strategy.Ung, M.-C. ; Garrett, L. ; Dalke, C. ; Leitner, V. ; Dragosa, D. ; Hladik, D ; Neff, F. ; Wagner, F. ; Zitzelsberger, H. ; Miller, G. ; Hrabě de Angelis, M. ; Rößler, U. ; Vogt Weisenhorn, D.M. ; Wurst, W. ; Graw, J. ; Hölter, S.M.
Dose-dependent long-term effects of a single radiation event on behaviour and glial cells.Russo, G.L. ; Sonsalla, G. ; Natarajan, P. ; Breunig, C. ; Bulli, G. ; Merl-Pham, J. ; Schmitt, S. ; Giehrl-Schwab, J. ; Giesert, F. ; Jastroch, M. ; Zischka, H. ; Wurst, W. ; Stricker, S.H. ; Hauck, S.M. ; Masserdotti, G. ; Götz, M.
CRISPR-mediated induction of neuron-enriched mitochondrial proteins boosts direct glia-to-neuron conversion.Baumann, P. ; Schriever, S.C. ; Kullmann, S. ; Zimprich, A. ; Peter, A. ; Gailus-Durner, V. ; Fuchs, H. ; Hrabě de Angelis, M. ; Wurst, W. ; Tschöp, M.H. ; Heni, M. ; Hölter, S.M. ; Pfluger, P.T.
Diabetes type 2 risk gene Dusp8 is associated with altered sucrose reward behavior in mice and humans.Kandaswamy, D.K. ; Prakash, M.V.S. ; Graw, J. ; Koller, S. ; Magyar, I. ; Tiwari, A. ; Berger, W. ; Santhiya, S.T.
Application of WES towards molecular investigation of congenital cataracts: Identification of novel alleles and genes in a hospital-based cohort of South India.Shams, S.F. ; Ghazanfari, M.R. ; Pettinger, S. ; Tavabi, A.H. ; Siemensmeyer, K. ; Smekhova, A. ; Dunin-Borkowski, R.E. ; Westmeyer, G.G. ; Schmitz-Antoniak, C.
Structural perspective on revealing heat dissipation behavior of CoFe2O4-Pd nanohybrids: Great promise for magnetic fluid hyperthermia.Bus, C. ; Zizmare, L. ; Feldkaemper, M. ; Geisler, S. ; Zarani, M. ; Schaedler, A. ; Klose, F. ; Admard, J. ; Mageean, C.J. ; Arena, G. ; Fallier-Becker, P. ; Ugun-Klusek, A. ; Maruszczak, K.K. ; Kapolou, K. ; Schmid, B. ; Rapaport, D. ; Ueffing, M. ; Casadei, N. ; Kruger, R. ; Gasser, T. ; Weisenhorn, D.M. ; Kahle, P.J. ; Trautwein, C. ; Gloeckner, C.J. ; Fitzgerald, J.C.
Human dopaminergic neurons lacking PINK1 exhibit disrupted dopamine metabolism related to vitamin B6 co-factors.Nouri, P. ; Götz, S. ; Rauser, B. ; Irmler, M. ; Peng, C. ; Trümbach, D. ; Kempny, C. ; Lechermeier, C.G. ; Bryniok, A. ; Dlugos, A. ; Euchner, E. ; Beckers, J. ; Brodski, C. ; Klümper, C. ; Wurst, W. ; Prakash, N.
Dose-dependent and subset-specific regulation of midbrain dopaminergic neuron differentiation by LEF1-mediated WNT1/b-catenin signaling.Boussaad, I. ; Obermaier, C.D. ; Hanss, Z. ; Bobbili, D.R. ; Bolognin, S. ; Glaab, E. ; Wołyńska, K. ; Weisschuh, N. ; De Conti, L. ; May, C. ; Giesert, F. ; Grossmann, D. ; Lambert, A. ; Kirchen, S. ; Biryukov, M. ; Burbulla, L.F. ; Massart, F. ; Bohler, J. ; Cruciani, G. ; Schmid, B. ; Kurz-Drexler, A. ; May, P. ; Duga, S. ; Klein, C. ; Schwamborn, J.C. ; Marcus, K. ; Woitalla, D. ; Vogt Weisenhorn, D.M. ; Wurst, W. ; Baralle, M. ; Krainc, D. ; Gasser, T. ; Wissinger, B. ; Krüger, R.
A patient-based model of RNA mis-splicing uncovers treatment targets in Parkinson's disease.Heppt, J. ; Wittmann, M.T. ; Schäffner, I. ; Billmann, C. ; Zhang, J. ; Vogt Weisenhorn, D.M. ; Prakash, N. ; Wurst, W. ; Taketo, M.M. ; Lie, D.C.C.
β-catenin signaling modulates the tempo of dendritic growth of adult-born hippocampal neurons.Takalo, M. ; Wittrahm, R. ; Wefers, B. ; Parhizkar, S. ; Jokivarsi, K. ; Kuulasmaa, T. ; Mäkinen, P. ; Martiskainen, H. ; Wurst, W. ; Xiang, X. ; Marttinen, M. ; Poutiainen, P. ; Haapasalo, A. ; Hiltunen, M. ; Haass, C.
The Alzheimer's disease-associated protective Plc gamma 2-P522R variant promotes immune functions.Werner, G. ; Damme, M. ; Schludi, M. ; Gnoerich, J. ; Wind, K. ; Fellerer, K. ; Wefers, B. ; Wurst, W. ; Edbauer, D. ; Brendel, M. ; Haass, C. ; Capell, A.
Loss of TMEM106B potentiates lysosomal and FTLD-like pathology in progranulin-deficient mice.Timofeev, O. ; Koch, L. ; Niederau, C. ; Tscherne, A. ; Schneikert, J. ; Klimovich, M. ; Elmshäuser, S. ; Zeitlinger, M. ; Mernberger, M. ; Nist, A. ; Osterburg, C. ; Dötsch, V. ; Hrabě de Angelis, M. ; Stiewe, T. ; German Mouse Clinic Consortium (Aguilar-Pimentel, J.A. ; Schmidt-Weber, C.B. ; Becker, L. ; Klopstock, T. ; Cho, Y.-L. ; Spielmann, N. ; Amarie, O.V. ; Garrett, L. ; Hölter, S.M. ; Wurst, W. ; Calzada-Wack, J. ; Sanz-Moreno, A. ; Klein-Rodewald, T. ; Rathkolb, B. ; Wolf, E. ; Östereicher, M.A. ; Miller, G. ; Maier, H. ; Stoeger, C. ; Leuchtenberger, S. ; Gailus-Durner, V. ; Fuchs, H.)
Phosphorylation control of p53 DNA binding cooperativity balances tumorigensis and aging.Kandaswamy, D.K. ; Vasantha, K. ; Graw, J. ; Santhiya, S.T.
A novel CRYGC E128* mutation underlying an autosomal dominant nuclear cataract in a south Indian kindred.Schriever, S.C. ; Kabra, D.G. ; Pfuhlmann, K. ; Baumann, P. ; Baumgart, E.V. ; Nagler, J. ; Seebacher, F. ; Harrison, L. ; Irmler, M. ; Kullmann, S. ; Corrêa-da-Silva, F. ; Giesert, F. ; Jain, R. ; Schug, H. ; Castel, J. ; Martinez, S. ; Wu, M. ; Häring, H.-U. ; Hrabě de Angelis, M. ; Beckers, J. ; Müller, T.D. ; Stemmer, K. ; Wurst, W. ; Rozman, J. ; Nogueiras, R. ; de Angelis, M. ; Molkentin, J.D. ; Krahmer, N. ; Yi, C.-X. ; Schmidt, M.V. ; Luquet, S. ; Heni, M. ; Tschöp, M.H. ; Pfluger, P.T.
Type 2 diabetes risk gene Dusp8 regulates hypothalamic Jnk signaling and insulin sensitivity.Blechner, C. ; Becker, L. ; Fuchs, H. ; Rathkolb, B. ; Prehn, C. ; Adler, T. ; Calzada-Wack, J. ; Garrett, L. ; Gailus-Durner, V. ; Morellini, F. ; Conrad, S. ; Hölter, S.M. ; Wolf, E. ; Klopstock, T. ; Adamski, J. ; Busch, D. ; Hrabě de Angelis, M. ; Schmeisser, M.J. ; Windhorst, S.
Physiological relevance of the neuronal isoform of inositol-1,4,5-trisphosphate 3-kinases in mice.Gabashvili, A.N. ; Chmelyuk, N.S. ; Efremova, M.V. ; Malinovskaya, J.A. ; Semkina, A.S. ; Abakumov, M.A.
Encapsulins-bacterial protein nanocompartments: Structure, properties, and application.Giegling, I. ; Hartmann, A.M. ; Genius, J. ; Konte, B. ; Maul, S. ; Straube, A. ; Eggert, T. ; Mulert, C. ; Leicht, G. ; Karch, S. ; Hegerl, U. ; Pogarell, O. ; Hölter, S.M. ; Möller, H.J. ; Graw, J. ; Rujescu, D.
Polymorphisms in CRYBB2 encoding βB2-crystallin are associated with antisaccade performance and memory function.Lüningschrör, P. ; Werner, G. ; Stroobants, S. ; Kakuta, S. ; Dombert, B. ; Sinske, D. ; Wanner, R. ; Lüllmann-Rauch, R. ; Wefers, B. ; Wurst, W. ; D'Hooge, R. ; Uchiyama, Y. ; Sendtner, M. ; Haass, C. ; Saftig, P. ; Knöll, B. ; Capell, A. ; Damme, M.
The FTLD risk factor TMEM106B regulates the transport of lysosomes at the axon initial segment of motoneurons.Chakroun, T. ; Evsyukov, V. ; Nykänen, N.P. ; Höllerhage, M. ; Schmidt, A. ; Kamp, F. ; Ruf, V.C. ; Wurst, W. ; Rösler, T.W. ; Höglinger, G.U.
Alpha-synuclein fragments trigger distinct aggregation pathways.Vogl, A.M. ; Phu, L. ; Becerra, R. ; Giusti, S.A. ; Verschueren, E. ; Hinkle, T.B. ; Bordenave, M.D. ; Adrian, M. ; Heidersbach, A. ; Yankilevich, P. ; Stefani, F.D. ; Wurst, W. ; Hoogenraad, C.C. ; Kirkpatrick, D.S. ; Refojo, D. ; Sheng, M.
Global site-specific neddylation profiling reveals that NEDDylated cofilin regulates actin dynamics.Kollmus, H. ; Fuchs, H. ; Lengger, C. ; Haselimashhadi, H. ; Bogue, M.A. ; Östereicher, M.A. ; Horsch, M. ; Adler, T. ; Aguilar-Pimentel, J.A. ; Amarie, O.V. ; Becker, L. ; Beckers, J. ; Calzada-Wack, J. ; Garrett, L. ; Hans, W. ; Hölter, S.M. ; Klein-Rodewald, T. ; Maier, H. ; Mayer-Kuckuk, P. ; Miller, G. ; Moreth, K. ; Neff, F. ; Rathkolb, B. ; Rácz, I. ; Rozman, J. ; Spielmann, N. ; Treise, I. ; Busch, D.H. ; Graw, J. ; Klopstock, T. ; Wolf, E. ; Wurst, W. ; Yildirim, A.Ö. ; Mason, J. ; Torres, A. ; Balling, R. ; Mehaan, T. ; Gailus-Durner, V. ; Schughart, K. ; Hrabě de Angelis, M.
A comprehensive and comparative phenotypic analysis of the collaborative founder strains identifies new and known phenotypes.Ignatova, V.V. ; Stolz, P. ; Kaiser, S. ; Gustafsson, T.H. ; Lastres, P.R. ; Sanz-Moreno, A. ; Cho, Y.-L. ; Amarie, O.V. ; Aguilar-Pimentel, J.A. ; Klein-Rodewald, T. ; Calzada-Wack, J. ; Becker, L. ; Marschall, S. ; Kraiger, M. ; Garrett, L. ; Seisenberger, C. ; Hölter, S.M. ; Borland, K. ; Van De Logt, E. ; Jansen, P.W.T.C. ; Baltissen, M.P. ; Valenta, M. ; Vermeulen, M. ; Wurst, W. ; Gailus-Durner, V. ; Fuchs, H. ; Hrabě de Angelis, M. ; Rando, O.J. ; Kellner, S.M. ; Bultmann, S. ; Schneider, R.
The rRNA m6A methyltransferase METTL5 is involved in pluripotency and developmental programs.Moretti, A. ; Fonteyne, L. ; Giesert, F. ; Hoppmann, P. ; Meier, A.B. ; Bozoglu, T. ; Baehr, A. ; Schneider, C.M. ; Sinnecker, D. ; Klett, K. ; Fröhlich, T. ; Rahman, F.A. ; Haufe, T. ; Sun, S. ; Jurisch, V. ; Kessler, B. ; Hinkel, R. ; Dirschinger, R. ; Martens, E. ; Jilek, C. ; Graf, A. ; Krebs, S. ; Santamaria, G. ; Kurome, M. ; Zakhartchenko, V. ; Campbell, B. ; Voelse, K. ; Wolf, A. ; Ziegler, T. ; Reichert, S. ; Lee, S. ; Flenkenthaler, F. ; Dorn, T. ; Jeremias, I. ; Blum, H. ; Dendorfer, A. ; Schnieke, A. ; Krause, S. ; Walter, M.C. ; Klymiuk, N. ; Laugwitz, K.L. ; Wolf, E. ; Wurst, W. ; Kupatt, C.
Somatic gene editing ameliorates skeletal and cardiac muscle failure in pig and human models of Duchenne muscular dystrophy.Cacheiro, P. ; Muñoz-Fuentes, V. ; Murray, S.A. ; Dickinson, M.E. ; Bucan, M. ; Nutter, L.M.J. ; Peterson, K.A. ; Haselimashhadi, H. ; Flenniken, A.M. ; Morgan, H. ; Westerberg, H. ; Konopka, T. ; Hsu, C.W. ; Christiansen, A.V. ; Lanza, D.G. ; Beaudet, A.L. ; Heaney, J.D. ; Fuchs, H. ; Gailus-Durner, V. ; Sorg, T. ; Prochazka, J. ; Novosadova, V. ; Lelliott, C.J. ; Wardle-Jones, H. ; Wells, S. ; Teboul, L. ; Cater, H. ; Stewart, M. ; Hough, T. ; Wurst, W. ; Sedlacek, R. ; Adams, D.J. ; Seavitt, J.R. ; Tocchini-Valentini, G. ; Mammano, F. ; Braun, R.E. ; McKerlie, C. ; Herault, Y. ; Hrabě de Angelis, M. ; Mallon, A.M. ; Lloyd, K.C.K. ; Brown, S.D.M. ; Parkinson, H. ; Meehan, T.F. ; Smedley, D. ; International Mouse Phenotyping Consortium (Marschall, S. ; Lengger, C. ; Maier, H. ; Seisenberger, C. ; Bürger, A. ; Kühn, R. ; Schick, J. ; Hörlein, A. ; Oritz, O. ; Giesert, F. ; Beig, J.)
Human and mouse essentiality screens as a resource for disease gene discovery.Garrett, L. ; Chang, Y.J. ; Niedermeier, K.M. ; Heermann, T. ; Enard, W. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Huttner, W.B. ; Wurst, W. ; Hölter, S.M.
A truncating Aspm allele leads to a complex cognitive phenotype and region-specific reductions in parvalbuminergic neurons.Lloyd, K.C.K. ; Adams, D.J. ; Baynam, G. ; Beaudet, A.L. ; Bosch, F. ; Boycott, K.M. ; Braun, R.E. ; Caulfield, M. ; Cohn, R. ; Dickinson, M.E. ; Dobbie, M.S. ; Flenniken, A.M. ; Flicek, P. ; Galande, S. ; Gao, X. ; Grobler, A. ; Heaney, J.D. ; Herault, Y. ; Hrabě de Angelis, M. ; Lupski, J.R. ; Lyonnet, S. ; Mallon, A.M. ; Mammano, F. ; MacRae, C.A. ; McInnes, R. ; McKerlie, C. ; Meehan, T.F. ; Murray, S.A. ; Nutter, L.M.J. ; Obata, Y. ; Parkinson, H. ; Pepper, M.S. ; Sedlacek, R. ; Seong, J.K. ; Shiroishi, T. ; Smedley, D. ; Tocchini-Valentini, G. ; Valle, D. ; Wang, C.-K.L. ; Wells, S. ; White, J. ; Wurst, W. ; Xu, Y. ; Brown, S.D.M.
The deep genome project.Yan, X. ; Atorf, J. ; Ramos, D. ; Thiele, F. ; Weber, S. ; Dalke, C. ; Sun, M. ; Puk, O. ; Michel, D. ; Fuchs, H. ; Klaften, M. ; Przemeck, G.K.H. ; Sabrautzki, S. ; Favor, J. ; Ruberte, J. ; Kremers, J. ; Hrabě de Angelis, M. ; Graw, J. ; German Mouse Clinic Consortium
Mutation in Bmpr1b leads to optic disc coloboma and ventral retinal gliosis in mice.Vogl, A.M. ; Phu, L. ; Becerra, R. ; Giusti, S.A. ; Verschueren, E. ; Hinkle, T.B. ; Bordenave, M.D. ; Adrian, M. ; Heidersbach, A. ; Yankilevich, P. ; Stefani, F.D. ; Wurst, W. ; Hoogenraad, C.C. ; Kirkpatrick, D.S. ; Refojo, D. ; Sheng, M.
Publisher Correction: Global site-specific neddylation profiling reveals that NEDDylated cofilin regulates actin dynamics (Nature Structural & Molecular Biology, (2020), 27, 2, (210-220), 10.1038/s41594-019-0370-3).Torres-Mejia, E. ; Trümbach, D. ; Kleeberger, C. ; Dornseifer, U. ; Orschmann, T. ; Bäcker, T. ; Brenke, J.K. ; Hadian, K. ; Wurst, W. ; López-Schier, H. ; Desbordes, S.C.
Sox2 controls Schwann cell self-organization through fibronectin fibrillogenesis.Rudan Njavro, J. ; Klotz, J. ; Dislich, B. ; Wanngren, J. ; Shmueli, M.D. ; Herber, J. ; Kuhn, P.H. ; Kumar, R. ; Koeglsperger, T. ; Conrad, M. ; Wurst, W. ; Feederle, R. ; Vlachos, A. ; Michalakis, S. ; Jedlicka, P. ; Müller, S.A. ; Lichtenthaler, S.F.
Mouse brain proteomics establishes MDGA1 and CACHD1 as in vivo substrates of the Alzheimer protease BACE1.Bajerski, F. ; Bürger, A. ; Glasmacher, B. ; Keller, E.R.J. ; Müller, K. ; Mühldorfer, K. ; Nagel, M. ; Rüdel, H. ; Müller, T. ; Schenkel, J. ; Overmann, J.
Factors determining microbial colonization of liquid nitrogen storage tanks used for archiving biological samples.Lucienne, M. ; Aguilar-Pimentel, J.A. ; Amarie, O.V. ; Becker, L. ; Calzada-Wack, J. ; Da Silva-Buttkus, P. ; Garrett, L. ; Hölter, S.M. ; Mayer-Kuckuk, P. ; Rathkolb, B. ; Rozman, J. ; Spielmann, N. ; Treise, I. ; Busch, D.H. ; Klopstock, T. ; Schmidt-Weber, C.B. ; Wolf, E. ; Wurst, W. ; Forny, M. ; Mathis, D. ; Fingerhut, R. ; Froese, D.S. ; Gailus-Durner, V. ; Fuchs, H. ; Hrabě de Angelis, M. ; Baumgartner, M.R.
In-depth phenotyping reveals common and novel disease symptoms in a hemizygous knock-in mouse model (Mut-ko/ki) of mut-type methylmalonic aciduria.Pawliczek, D. ; Dalke, C. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Graw, J. ; Amarie, O.V.
Spectral domain - Optical coherence tomography (SD-OCT) as a monitoring tool for alterations in mouse lenses.Hladik, D. ; Dalke, C. ; von Toerne, C. ; Hauck, S.M. ; Azimzadeh, O. ; Philipp, J. ; Ung, M.-C. ; Schlattl, H. ; Rößler, U. ; Graw, J. ; Atkinson, M.J. ; Tapio, S.
Creb signaling mediates dose-dependent radiation response in the murine hippocampus two years after total body exposure.Haselimashhadi, H. ; Mason, J.C. ; Muñoz-Fuentes, V. ; López-Gómez, F. ; Babalola, K. ; Acar, E.F. ; Kumar, V. ; White, J. ; Flenniken, A.M. ; King, R. ; Straiton, E. ; Seavitt, J.R. ; Gaspero, A. ; Garza, A. ; Christianson, A.E. ; Hsu, C.-W. ; Reynolds, C.L. ; Lanza, D.G. ; Lorenzo, I. ; Green, J.R. ; Gallegos, J.J. ; Bohat, R. ; Samaco, R.C. ; Veeraragavan, S. ; Kim, J.K. ; Miller, G. ; Fuchs, H. ; Garrett, L. ; Becker, L. ; Kang, Y.K. ; Clary, D. ; Cho, S.Y. ; Tamura, M. ; Tanaka, N. ; Soo, K.D. ; Bezginov, A. ; About, G.B. ; Champy, M.-F. ; Vasseur, L. ; Leblanc, S. ; Meziane, H. ; Selloum, M. ; Reilly, P.T. ; Spielmann, N. ; Maier, H. ; Gailus-Durner, V. ; Sorg, T. ; Hiroshi, M. ; Yuichi, O. ; Heaney, J.D. ; Dickinson, M.E. ; Wurst, W. ; Tocchini-Valentini, G.P. ; Lloyd, K.C.K. ; McKerlie, C. ; Seong, J.K. ; Herault, Y. ; Hrabě de Angelis, M. ; Brown, S.D.M. ; Smedley, D. ; Flicek, P. ; Mallon, A.-M. ; Parkinson, H. ; Meehan, T.F.
Soft windowing application to improve analysis of high-throughput phenotyping data.Altamura, S. ; Vegi, N.M. ; Hoppe, P.S. ; Schroeder, T. ; Aichler, M. ; Walch, A.K. ; Okreglicka, K. ; Hültner, L. ; Schneider, M. ; Ladinig, C. ; Kuklik-Roos, C. ; Mysliwietz, J. ; Janik, D. ; Neff, F. ; Rathkolb, B. ; Hrabě de Angelis, M. ; Buske, C. ; da Silva, A.R. ; Muedder, K. ; Conrad, M. ; Ganz, T. ; Kopf, M. ; Muckenthaler, M.U. ; Bornkamm, G.W.
Glutathione peroxidase 4 and vitamin E control reticulocyte maturation, stress erythropoiesis and iron homeostasis.Graw, J.
Mutation in the mouse histone gene Hist2h3c1 leads to degeneration of the lens vesicle and severe microphthalmia.Pawliczek, D.
Cataract type in mouse exposed to moderate doses of ionizing radiation depends on mouse age at irradiation.Baumann, P. ; Schriever, S.C. ; Kullmann, S. ; Zimprich, A. ; Feuchtinger, A. ; Amarie, O.V. ; Peter, A. ; Walch, A.K. ; Gailus-Durner, V. ; Fuchs, H. ; Hrabě de Angelis, M. ; Wurst, W. ; Tschöp, M.H. ; Heni, M. ; Hölter, S.M. ; Pfluger, P.T.
Dusp8 affects hippocampal size and behavior in mice and humans.Doll, S. ; Freitas, F.P. ; Shah, R. ; Aldrovandi, M. ; da Silva, M.C. ; Ingold, I. ; Grocin, A.G. ; Xavier da Silva, T.N. ; Panzilius, E. ; Scheel, C. ; Mourao, A. ; Buday, K. ; Sato, M. ; Wanninger, J. ; Vignane, T. ; Mohana, V. ; Rehberg, M. ; Flatley, A. ; Schepers, A. ; Kurz, A. ; White, D. ; Sauer, M. ; Sattler, M. ; Tate, E.W. ; Schmitz, W. ; Schulze, A. ; O’Donnell, V. ; Proneth, B. ; Popowicz, G.M. ; Pratt, D.A. ; Angeli, J.P.F. ; Conrad, M.
FSP1 is a glutathione-independent ferroptosis suppressor.Rubio-Aliaga, I. ; Daryadel, A. ; Ruiz, P.A. ; Gehring, N. ; Fuente, R. ; Stojanovic, D. ; Ugrica, M. ; Bettoni, C. ; Sabrautzki, S. ; Pastor-Arroyo, E.M. ; Frey-Wagner, I. ; Lorenz-Depiereux, B. ; Diener, S. ; Gil-Pena, H. ; Michalke, B. ; Strom, T.M. ; Hrabě de Angelis, M. ; Rogler, G. ; Santos, F. ; Wagner, C.A.
Constitutive activation of Jak1 leads to increased fibroblast growth factor 23 levels in mice.Stefanoiu, A. ; Page, J. ; Symvoulidis, P. ; Westmeyer, G.G. ; Lasser, T.
Artifact-free deconvolution in light field microscopy.Seeger, M. ; Westmeyer, G.G. ; Ntziachristos, V.
In vivo hybrid microscopy of small model organisms.Schoetz, J. ; Conrad, M. ; Geissler, E.K. ; Kroemer, A. ; Proneth, B. ; Schlitt, H.J. ; Eggenhofer, E.
Role of ferroptosis and ischemia reperfusion injury in liver transplantations.Eggenhofer, E. ; Proneth, B. ; Doll, S. ; Schoetz, J. ; Conrad, M. ; Schlitt, H. ; Geissler, E.K.
Activation of innate immune cells by ferroptosis in hepatic ischemia reperfusion injury.Vetrivel, S. ; Graw, J. ; Giesert, F.
Identification of ocular regulatory functions of core histone variant H3.2 in mouse.Wang, Y. ; Wu, H. ; Zelenin, P. ; Fontanet, P. ; Wanderoy, S. ; Petitpré, C. ; Comai, G. ; Bellardita, C. ; Xue-Franzén, Y. ; Huettl, R.E. ; Huber, A.B. ; Tajbakhsh, S. ; Kiehn, O. ; Ernfors, P. ; Deliagina, T.G. ; Lallemend, F. ; Hadjab, S.
Muscle-selective RUNX3 dependence of sensorimotor circuit development.Vidali, S. ; Urquhart, J. ; Rozman, J. ; Thompson, K. ; Sanders, C. ; Jamson, E. ; Breen, C. ; Rathkolb, B. ; Da Silva-Buttkus, P. ; Marschall, S. ; Amarie, O.V. ; Aguilar-Pimentel, J.A. ; Calzada-Wack, J. ; Becker, L. ; Cho, Y. ; Garrett, L. ; Hölter, S.M. ; Klein-Rodewald, T. ; Mayer-Kuckuk, P. ; Treise, I. ; Zimprich, A. ; Gampe, K. ; Leuchtenberger, S. ; Pfannes, K. ; Stoeger, C. ; Maier, H. ; Graw, J. ; Wurst, W. ; Höfig, K.P. ; Feichtinger, R.G. ; Gaertner, U. ; Szibor, M. ; Wittig, I. ; Mayr, J.A. ; Newman, W. ; Fuchs, H. ; Taylor, R.W. ; Gailus-Durner, V. ; Prokisch, H. ; Hrabě de Angelis, M.
A homozygous two exon deletion in UQCRH: Matching mouse and human phenotype.Lorenz, S. ; Conrad, M.
Ferroptose: Tod durch Eisenabhängige Lipidperoxidation.Solga, R. ; Behrens, J. ; Ziemann, A. ; Riou, A. ; Berwanger, C. ; Becker, L. ; Garrett, L. ; Hrabě de Angelis, M. ; Fischer, L. ; Coras, R. ; Barkovits, K. ; Marcus, K. ; Mahabir, E. ; Eichinger L ; Schröder, R. ; Noegel, A.A. ; Clemen, C.S. ; German Mouse Clinic Consortium (Aguilar-Pimentel, J.A. ; Schmidt-Weber, C.B. ; Adler, T. ; Treise, I. ; Moreth, K. ; Hölter, S.M. ; Zimprich, A. ; Wurst, W. ; Amarie, O.V. ; Graw, J. ; Rozman, J. ; Calzada-Wack, J. ; Rathkolb, B. ; Östereicher, M.A. ; Miller, G. ; Lengger, C. ; Maier, H. ; Stoeger, C. ; Leuchtenberger, S. ; Gailus-Durner, V. ; Fuchs, H.)
CRN2 binds to TIMP4 and MMP14 and promotes perivascular invasion of glioblastoma cells.Uribe-Mariño, A. ; Castiblanco-Urbina, M.A. ; Falconi-Sobrinho, L.L. ; dos Anjos-Garcia, T. ; de Oliveira, R.C. ; Mendes-Gomes, J. ; da Silva Soares, R. ; Matthiesen, M. ; Almada, R.C. ; De Oliveira, R. ; Coimbra, N.C.
The alpha- and beta-noradrenergic receptors blockade in the dorsal raphe nucleus impairs the panic-like response elaborated by medial hypothalamus neurons.Fecher, C. ; Trovò, L. ; Müller, S.A. ; Snaidero, N. ; Wettmarshausen, J. ; Heink, S. ; Ortiz, O. ; Wagner, I. ; Kühn, R. ; Hartmann, J. ; Karl, R.M. ; Konnerth, A. ; Korn, T. ; Wurst, W. ; Merkler, D. ; Lichtenthaler, S.F. ; Perocchi, F. ; Misgeld, T.
Cell-type-specific profiling of brain mitochondria reveals functional and molecular diversity.Castro Dias, M. ; Coisne, C. ; Baden, P. ; Enzmann, G. ; Garrett, L. ; Becker, L. ; Hölter, S.M. ; Hrabě de Angelis, M. ; Deutsch, U. ; Engelhardt, B. ; German Mouse Clinic Consortium (Aguilar-Pimentel, J.A. ; Adler, T. ; Spielmann, N. ; Moreth, K. ; Hans, W. ; Amarie, O.V. ; Graw, J. ; Rozman, J. ; Neff, F. ; Calzada-Wack, J. ; Rathkolb, B. ; Wurst, W. ; Beckers, J. ; Östereicher, M.A. ; Miller, G. ; Maier, H. ; Stoeger, C. ; Leuchtenberger, S. ; Gailus-Durner, V. ; Fuchs, H.)
Claudin-12 is not required for blood-brain barrier tight junction function.Dalke, C. ; Pawliczek, D. ; Graw, J. ; LDLensRad Consortium
Cataract development after gamma irradiation in miceSigmund, F. ; Pettinger, S. ; Kube, M. ; Schneider, F. ; Schifferer, M. ; Schneider, S. ; Efremova, M.V. ; Pujol-Martí, J. ; Aichler, M. ; Walch, A.K. ; Misgeld, T. ; Dietz, H. ; Westmeyer, G.G.
Iron-sequestering nanocompartments as multiplexed Electron Microscopy gene reporters.von Gamm, M. ; Schaub, A. ; Jones, A. ; Wolf, C. ; Behrens, G. ; Lichti, J. ; Essig, K. ; Macht, A. ; Pircher, J. ; Ehrlich, A. ; Davari, K. ; Chauhan, D. ; Busch, B. ; Wurst, W. ; Feederle, R. ; Feuchtinger, A. ; Tschöp, M.H. ; Friedel, C.C. ; Hauck, S.M. ; Sattler, M. ; Geerlof, A. ; Hornung, V. ; Heissmeyer, V. ; Schulz, C. ; Heikenwalder, M. ; Glasmacher, E.
Immune homeostasis and regulation of the interferon pathway require myeloid-derived Regnase-3.Figeac, N. ; Mohamed, A.D. ; Sun, C. ; Schönfelder, M. ; Matallanas, D. ; Garcia-Munoz, A. ; Missiaglia, E. ; Collie-Duguid, E. ; De Mello, V. ; Pobbati, A.V. ; Pruller, J. ; Jaka, O. ; Harridge, S.D.R. ; Hong, W. ; Shipley, J. ; Vargesson, N. ; Zammit, P.S. ; Wackerhage, H.
VGLL3 operates via TEAD1, TEAD3 and TEAD4 to influence myogenesis in skeletal muscle.Segal, J. ; Mülleder, M. ; Krüger, A. ; Adler, T. ; Scholze-Wittler, M. ; Becker, L. ; Calzada-Wack, J. ; Garrett, L. ; Hölter, S.M. ; Rathkolb, B. ; Rozman, J. ; Rácz, I. ; Fischer, R. ; Busch, D.H. ; Neff, F. ; Klingenspor, M. ; Klopstock, T. ; Grüning, N.M. ; Michel, S. ; Lukaszewska-McGreal, B. ; Voigt, I. ; Hartmann, L. ; Timmermann, B. ; Lehrach, H. ; Wolf, E. ; Wurst, W. ; Gailus-Durner, V. ; Fuchs, H. ; Hrabě de Angelis, M. ; Schrewe, H. ; Yuneva, M. ; Ralser, M.
Low catalytic activity is insufficient to induce disease pathology in triosephosphate isomerase deficiency.Friedmann Angeli, J.P. ; Krysko, D.V. ; Conrad, M.
Ferroptosis at the crossroads of cancer-acquired drug resistance and immune evasion.Graw, J. ; Vetrivel, S. ; Fuchs, H. ; Sabrautzki, S. ; Tiso, N.
Mutation in the mouse histone gene Hist2h3c1 leads to degeneration of the lens vesicle and severe microphthalmia.Vetrivel, S. ; Tiso, N. ; Kügler, A. ; Irmler, M. ; Horsch, M. ; Beckers, J. ; Hladik, D. ; Giesert, F. ; Gailus-Durner, V. ; Fuchs, H. ; Sabrautzki, S. ; Adler, T. ; Treise, I. ; Busch, D.H. ; Aguilar-Pimentel, J.A. ; Ollert, M. ; Götz, A. ; Amarie, O.V. ; Stöger, T. ; Schulz, H. ; Becker, L. ; Klopstock, T. ; Schrewe, A. ; Spielmann, N. ; Bekeredjian, R. ; Garrett, L. ; Hölter, S.M. ; Zimprich, A. ; Wurst, W. ; Mayer-Kuckuk, P. ; Hans, W. ; Rozman, J. ; Klingenspor, M. ; Neff, F. ; da Silva Buttkus, P. ; Calzada-Wack, J. ; Rácz, I. ; Zimmer, A. ; Rathkolb, B. ; Wolf, E. ; Prehn, C. ; Adamski, J. ; Östereicher, M.A. ; Miller, G. ; Steinkamp, R. ; Lengger, C. ; Maier, H. ; Stoeger, C. ; Leuchtenberger, S. ; Hrabě de Angelis, M. ; Graw, J.
Mutation in the mouse histone gene Hist2h3c1 leads to degeneration of the lens vesicle and severe microphthalmia.van Well, E.M. ; Bader, V. ; Patra, M. ; Sánchez-Vicente, A. ; Meschede, J. ; Furthmann, N. ; Schnack, C. ; Blusch, A. ; Longworth, J. ; Petrasch-Parwez, E. ; Mori, K. ; Arzberger, T. ; Trümbach, D. ; Angersbach, L. ; Showkat, C. ; Sehr, D.A. ; Berlemann, L.A. ; Goldmann, P. ; Clement, A.M. ; Behl, C. ; Woerner, A.C. ; Saft, C. ; Wurst, W. ; Haass, C. ; Ellrichmann, G. ; Gold, R. ; Dittmar, G. ; Hipp, M.S. ; Hartl, F.U. ; Tatzelt, J. ; Winklhofer, K.F.
A protein quality control pathway regulated by linear ubiquitination.Graw, J.
Mouse models for microphthalmia, anophthalmia and cataracts.Fiebig, C. ; Keiner, S. ; Ebert, B. ; Schäffner, I. ; Jagasia, R. ; Lie, D.C. ; Beckervordersandforth, R.
Mitochondrial dysfunction in astrocytes impairs the generation of reactive astrocytes and enhances neuronal cell death in the cortex upon photothrombotic lesion.Funk, N. ; Munz, M. ; Ott, T. ; Brockmann, K. ; Wenninger-Weinzierl, A. ; Kühn, R. ; Vogt Weisenhorn, D.M. ; Giesert, F. ; Wurst, W. ; Gasser, T. ; Biskup, S.
The Parkinson's disease-linked Leucine-rich repeat kinase 2 (LRRK2) is required for insulin-stimulated translocation of GLUT4.Moore, B.A. ; Leonard, B.C. ; Sebbag, L. ; Edwards, S.G. ; Cooper, A. ; Imai, D.M. ; Straiton, E. ; Santos, L. ; Reilly, C. ; Griffey, S.M. ; Bower, L. ; Clary, D. ; Mason, J. ; Roux, M.J. ; Meziane, H. ; Herault, Y. ; McKerlie, C. ; Flenniken, A.M. ; Nutter, L.M.J. ; Berberovic, Z. ; Owen, C. ; Newbigging, S. ; Adissu, H. ; Eskandarian, M. ; Hsu, C.W. ; Kalaga, S. ; Udensi, U. ; Asomugha, C. ; Bohat, R. ; Gallegos, J.J. ; Seavitt, J.R. ; Heaney, J.D. ; Beaudet, A.L. ; Dickinson, M.E. ; Justice, M.J. ; Philip, V. ; Kumar, V. ; Svenson, K.L. ; Braun, R.E. ; Wells, S. ; Cater, H. ; Stewart, M. ; Clementson-Mobbs, S. ; Joynson, R. ; Gao, X. ; Suzuki, T. ; Wakana, S. ; Smedley, D. ; Seong, J.K. ; Tocchini-Valentini, G. ; Moore, M. ; Fletcher, C. ; Karp, N. ; Ramirez-Solis, R. ; White, J.K. ; Hrabě de Angelis, M. ; Wurst, W. ; Thomasy, S.M. ; Flicek, P. ; Parkinson, H. ; Brown, S.D.M. ; Meehan, T.F. ; Nishina, P.M. ; Murray, S.A. ; Krebs, M.P. ; Mallon, A.M. ; Kent Lloyd, K.C. ; Murphy, C.J. ; Moshiri, A.
Author Correction: Identification of genes required for eye development by high-throughput screening of mouse knockouts (Communications Biology, (2018), 1, 1, (236), 10.1038/s42003-018-0226-0).Kengara, F.O. ; Dörfler, U. ; Welzl, G. ; Munch, J.-C. ; Schroll, R.
Evidence of non-DDD pathway in the anaerobic degradation of DDT in tropical soil.Conrad, M. ; Proneth, B.
Broken hearts: Iron overload, ferroptosis and cardiomyopathy.Lauri, A. ; Soliman, D. ; Omar, M. ; Stelzl, A. ; Ntziachristos, V. ; Westmeyer, G.G.
Whole-cell photoacoustic sensor based on pigment relocalization.Höllerhage, M. ; Fussi, N. ; Rösler, T.W. ; Wurst, W. ; Behrends, C. ; Höglinger, G.U.
Multiple molecular pathways stimulating macroautophagy protect from alpha-synuclein-induced toxicity in human neurons.Li, C. ; Deng, X. ; Zhang, W. ; Xie, X. ; Conrad, M. ; Liu, Y. ; Friedmann Angeli, J.P.F. ; Lai, L.
Novel allosteric activators for ferroptosis regulator glutathione peroxidase 4.Heermann, T. ; Garrett, L. ; Wurst, W. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Graw, J. ; Hölter, S.M.
Crybb2 mutations consistently affect Schizophrenia endophenotypes in mice.Blume, J. ; Ziętara, N. ; Witzlau, K. ; Liu, Y. ; Ortiz, O. ; Puchałka, J. ; Winter, S.J. ; Kunze-Schumacher, H. ; Saran, N. ; Düber, S. ; Roy, B. ; Weiss, S. ; Klein, C. ; Wurst, W. ; Łyszkiewicz, M. ; Krueger, A.
miR-191 modulates B-cell development and targets transcription factors E2A, Foxp1, and Egr1.Seibt, T.M. ; Proneth, B. ; Conrad, M.
Role of GPX4 in ferroptosis and its pharmacological implication.Proneth, B. ; Conrad, M.
Ferroptosis and necroinflammation, a yet poorly explored link.Amarie, O.V. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Graw, J.
Animal case.Rauser, B.
Direct conversion of somatic cells utilizing CRISPR/Cas9.Breunig, C. ; Neuner, A.M. ; Giehrl-Schwab, J. ; Wurst, W. ; Götz, M. ; Stricker, S.H.
A customizable protocol for string assembly gRNA cloning (STAgR).Amoscato, A.A. ; Mikulska-Ruminska, K. ; Rosenbaum, J.C. ; Mao, G. ; Zhao, J. ; Conrad, M. ; Kellum, J.A. ; Wenzel, S.E. ; VanDemark, A.P. ; Bahar, I. ; Kagan, V.E. ; Baylr, H.
Empowerment of 15-lipoxygenase catalytic competence in selective oxidation of membrane ETE-PE to ferroptotic death signals, HpETE-PE.Moore, B.A. ; Leonard, B.C. ; Sebbag, L. ; Edwards, S.G. ; Cooper, A. ; Imai, D.M. ; Straiton, E. ; Santos, L. ; Reilly, C. ; Griffey, S.M. ; Bower, L. ; Clary, D. ; Mason, J. ; Roux, M.J. ; Meziane, H. ; Herault, Y. ; McKerlie, C. ; Flenniken, A.M. ; Nutter, L.M.J. ; Berberovic, Z. ; Owen, C. ; Newbigging, S. ; Adissu, H. ; Eskandarian, M. ; Hsu, C.W. ; Kalaga, S. ; Udensi, U. ; Asomugha, C. ; Bohat, R. ; Gallegos, J.J. ; Seavitt, J.R. ; Heaney, J.D. ; Beaudet, A.L. ; Dickinson, M.E. ; Justice, M.J. ; Philip, V. ; Kumar, V. ; Svenson, K.L. ; Braun, R.E. ; Wells, S. ; Cater, H. ; Stewart, M. ; Clementson-Mobbs, S. ; Joynson, R. ; Gao, X. ; Suzuki, T. ; Wakana, S. ; Smedley, D. ; Seong, J.K. ; Tocchini-Valentini, G. ; Moore, M. ; Fletcher, C. ; Karp, N. ; Ramirez-Solis, R. ; White, J.K. ; Hrabě de Angelis, M. ; Wurst, W. ; Thomasy, S.M. ; Flicek, P. ; Parkinson, H. ; Brown, S.D.M. ; Meehan, T.F. ; Nishina, P.M. ; Murray, S.A. ; Krebs, M.P. ; Mallon, A.M. ; Lloyd, K.C.K. ; Murphy, C.J. ; Moshiri, A.
Identification of genes required for eye development by high-throughput screening of mouse knockouts.Jensen, L.R. ; Garrett, L. ; Hölter, S.M. ; Rathkolb, B. ; Rácz, I. ; Adler, T. ; Prehn, C. ; Hans, W. ; Rozman, J. ; Becker, L. ; Aguilar-Pimentel, J.A. ; Puk, O. ; Moreth, K. ; Dopatka, M. ; Walther, D.J. ; von Bohlen Und Halbach, V. ; Rath, M. ; Delatycki, M. ; Bert, B. ; Fink, H. ; Blümlein, K. ; Ralser, M. ; Van Dijck, A. ; Kooy, F. ; Stark, Z. ; Müller, S. ; Scherthan, H. ; Gecz, J. ; Wurst, W. ; Wolf, E. ; Zimmer, A. ; Klingenspor, M. ; Graw, J. ; Klopstock, T. ; Busch, D. ; Adamski, J. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; von Bohlen und Halbach, O. ; Ropers, H.H. ; Kuss, A.W.
A mouse model for intellectual disability caused by mutations in the X-linked 2 '-O-methyltransferase Ftsj1 gene.di Giaimo, R. ; Durovic, T. ; Barquin, P. ; Kociaj, A. ; Lepko, T. ; Aschenbroich, S. ; Breunig, C. ; Irmler, M. ; Cernilogar, F.M. ; Schotta, G. ; Barbosa, J.S. ; Trümbach, D. ; Baumgart, E.V. ; Neuner, A.M. ; Beckers, J. ; Wurst, W. ; Stricker, S.H. ; Ninkovic, J.
The aryl hydrocarbon receptor pathway defines the time frame for restorative neurogenesis.Schotz, J. ; Proneth, B. ; Doll, S. ; Goecze, I. ; Schlitt, H.J. ; Geissler, E. ; Conrad, M. ; Eggenhofer, E.
Innate immune cells are activated by regulated cell death events in early hepatic ischemia reperfusion injury.Muri, J. ; Heer, S. ; Matsushita, M. ; Pohlmeier, L. ; Tortola, L. ; Fuhrer, T. ; Conrad, M. ; Zamboni, N. ; Kisielow, J. ; Kopf, M.
The thioredoxin-1 system is essential for fueling DNA synthesis during T-cell but not B-cell metabolic reprogramming and proliferation.Balta, E.A. ; Schäffner, I. ; Wittmann, M.T. ; Sock, E. ; von Zweydorf, F. ; von Wittgenstein, J. ; Steib, K. ; Heim, B. ; Kremmer, E. ; Häberle, B.M. ; Ueffing, M. ; Lie, D.C.C. ; Gloeckner, C.J.
Phosphorylation of the neurogenic transcription factor SOX11 on serine 133 modulates neuronal morphogenesis.Eggenhofer, E. ; Proneth, B. ; Doll, S. ; Seebauer, L. ; Conrad, M. ; Schlitt, H. ; Geissler, E.
Targeting innate immune cells and regulated cell death in early hepatic ischemia reperfusion injury.Xiang, X. ; Piers, T.M. ; Wefers, B. ; Zhu, K. ; Mallach, A. ; Brunner, B. ; Kleinberger, G. ; Song, W. ; Colonna, M. ; Herms, J. ; Wurst, W. ; Pocock, J.M. ; Haass, C.
The Trem2 R47H Alzheimer's risk variant impairs splicing and reduces Trem2 mRNA and protein in mice but not in humans.Schäffner, I. ; Minakaki, G. ; Khan, M.A. ; Balta, E.A. ; Schlötzer-Schrehardt, U. ; Schwarz, T.J. ; Beckervordersandforth, R. ; Winner, B. ; Webb, A.E. ; DePinho, R.A. ; Paik, J. ; Wurst, W. ; Klucken, J. ; Lie, D.C.C.
FoxO function is essential for maintenance of autophagic flux and neuronal morphogenesis in adult neurogenesis.Stanelle-Bertram, S. ; Walendy-Gnirß, K. ; Speiseder, T. ; Thiele, S. ; Asante, I.A. ; Dreier, C. ; Kouassi, N.M. ; Preuß, A. ; Pilnitz-Stolze, G. ; Müller, U. ; Thanisch, S. ; Richter, M. ; Scharrenberg, R. ; Kraus, V. ; Dörk, R. ; Schau, L. ; Herder, V. ; Gerhauser, I. ; Pfankuche, V.M. ; Käufer, C. ; Waltl, I. ; Moraes, T. ; Sellau, J. ; Hoenow, S. ; Schmidt-Chanasit, J. ; Jansen, S. ; Schattling, B. ; Ittrich, H. ; Bartsch, U. ; Renné, T. ; Bartenschlager, R. ; Arck, P. ; Cadar, D. ; Friese, M.A. ; Vapalahti, O. ; Lotter, H. ; Benites, S. ; Rolling, L. ; Gabriel, M. ; Baumgärtner, W. ; Morellini, F. ; Hölter, S.M. ; Amarie, O.V. ; Fuchs, H. ; Hrabě de Angelis, M. ; Löscher, W. ; Calderon de Anda, F. ; Gabriel, G.
Male offspring born to mildly ZIKV-infected mice are at risk of developing neurocognitive disorders in adulthood.Clemen, C.S. ; Winter, L. ; Strucksberg, K.H. ; Berwanger, C. ; Türk, M. ; Kornblum, C. ; Florin, A. ; Aguilar-Pimentel, J.A. ; Amarie, O.V. ; Becker, L. ; Garrett, L. ; Hans, W. ; Moreth, K. ; Neff, F. ; Pingen, L. ; Rathkolb, B. ; Rácz, I. ; Rozman, J. ; Treise, I. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Vorgerd, M. ; Eichinger, L. ; Schröder, R.
The heterozygous R155C VCP mutation: Toxic in humans! Harmless in mice?Weber, A. ; Schwarz, S.C. ; Tost, J. ; Trümbach, D. ; Winter, P. ; Busato, F. ; Tacik, P. ; Windhorst, A.C. ; Fagny, M. ; Arzberger, T. ; McLean, C. ; van Swieten, J.C. ; Schwarz, J. ; Vogt Weisenhorn, D.M. ; Wurst, W. ; Adhikary, T. ; Dickson, D.W. ; Höglinger, G.U. ; Müller, U.
Epigenome-wide DNA methylation profiling in Progressive Supranuclear Palsy reveals major changes at DLX1.Nikolakopoulou, P. ; Chatzigeorgiou, A. ; Kourtzelis, I. ; Toutouna, L. ; Masjkur, J. ; Arps-Forker, C. ; Poser, S.W. ; Rozman, J. ; Rathkolb, B. ; Aguilar-Pimentel, J.A. ; German Mouse Clinic Consortium ; Wolf, E. ; Klingenspor, M. ; Ollert, M. ; Schmidt-Weber, C.B. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Tsata, V. ; Sebastian Monasor, L. ; Troullinaki, M. ; Witt, A. ; Anastasiou, V. ; Chrousos, G. ; Yi, C.-X. ; García-Cáceres, C. ; Tschöp, M.H. ; Bornstein, S.R. ; Androutsellis-Theotokis, A. ; German Mouse Clinic Consortium (Garrett, L. ; Hölter, S.M. ; Zimprich, A. ; Wurst, W. ; Amarie, O.V. ; Graw, J. ; Neff, F.)
Streptozotocin-induced beta-cell damage, high fat diet, and metformin administration regulate Hes3 expression in the adult mouse brain.Garrett, L. ; Ung, M.-C. ; Heermann, T. ; Niedermeier, K.M. ; Hölter, S.M.
Analysis of neuropsychiatric disease-related functional neuroanatomical markers in mice.Fussi, N. ; Höllerhage, M. ; Chakroun, T. ; Nykänen, N.P. ; Rösler, T.W. ; Koeglsperger, T. ; Wurst, W. ; Behrends, C. ; Höglinger, G.U.
Exosomal secretion of alpha-synuclein as protective mechanism after upstream blockage of macroautophagy.Myklatun, A. ; Lauri, A. ; Eder, S.H.K. ; Cappetta, M. ; Shcherbakov, D. ; Wurst, W. ; Winklhofer, M. ; Westmeyer, G.G.
Author Correction: Zebrafish and medaka offer insights into the neurobehavioral correlates of vertebrate magnetoreception (Nature Communications DOI: 10.1038/s41467-018-03090-6).Hassannia, B. ; Wiernicki, B. ; Ingold, I. ; Qu, F. ; Van Herck, S. ; Tyurina, Y.Y. ; Bayir, H. ; Abhari, B.A. ; Angeli, J.P.F. ; Choi, S.M. ; Meul, E. ; Heyninck, K. ; Declerck, K. ; Chirumamilla, C.S. ; Lahtela-Kakkonen, M. ; Van Camp, G. ; Krysko, D.V. ; Ekert, P.G. ; Fulda, S. ; De Geest, B.G. ; Conrad, M. ; Kagan, V.E. ; Berghe, W.V. ; Vandenabeele, P. ; Berghe, T.V.
Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma.Ingold, I. ; Conrad, M.
Selenium and iron, two elemental rivals in the ferroptotic death process.Conrad, M. ; Kagan, V.E. ; Bayir, H. ; Pagnussat, G.C. ; Head, B. ; Traber, M.G. ; Stockwell, B.R.
Regulation of lipid peroxidation and ferroptosis in diverse species.Shi, R. ; Cao, Z. ; Li, H. ; Graw, J. ; Zhang, G. ; Thannickal, V.J. ; Cheng, G.
Peroxidasin contributes to lung host defense by direct binding and killing of gram-negative bacteria.Lewerenz, J. ; Ates, G. ; Methner, A. ; Conrad, M. ; Maher, P.A.
Oxytosis/ferroptosis-(Re-) emerging roles for oxidative stress-dependent non-apoptotic cell death in diseases of the central nervous system. .Dedic, N. ; Kuehne, C. ; Jakovcevski, M. ; Hartmann, J. ; Genewsky, A.J. ; Gomes, K.S. ; Anderzhanova, E. ; Poehlmann, M.L. ; Chang, S. ; Kolarz, A. ; Vogl, A.M. ; Dine, J. ; Metzger, M.W. ; Schmid, B. ; Almada, R.C. ; Ressler, K.J. ; Wotjak, C.T. ; Grinevich, V. ; Chen, A. ; Schmidt, M.V. ; Wurst, W. ; Refojo, D. ; Deussing, J.M.
Chronic CRH depletion from GABAergic, long-range projection neurons in the extended amygdala reduces dopamine release and increases anxiety.Friedmann Angeli, J.P.F. ; Conrad, M.
Selenium and GPX4, a vital symbiosis.Vogt, M.A. ; Ehsaei, Z. ; Knuckles, P. ; Higginbottom, A. ; Helmbrecht, M.S. ; Kunath, T. ; Eggan, K. ; Williams, L.A. ; Shaw, P.J. ; Wurst, W. ; Floß, T. ; Huber, A.B. ; Taylor, V.
TDP-43 induces p53-mediated cell death of cortical progenitors and immature neurons.Friedmann Angeli, J.P.F. ; Conrad, M.
Lipoxygenases-killers against their will?Muri, J. ; Heer, S. ; Matsushita, M. ; Pohlmeier, L. ; Tortola, L. ; Fuhrer, T. ; Conrad, M. ; Zamboni, N. ; Kisielow, J. ; Kopf, M.
The thioredoxin-1 system is essential for fueling DNA synthesis during T-cell metabolic reprogramming and proliferation.Sun, M. ; Ahmad, N. ; Zhang, R. ; Graw, J.
Crybb2 associates with Tmsb4X and is crucial for dendrite morphogenesis.Rodriguez Camargo, D.C. ; Garg, D. ; Buday, K. ; Frankó, A. ; Rodriguez Camargo, A. ; Schmidt, F. ; Cox, S.J. ; Suladze, S. ; Haslbeck, M. ; Mideksa, Y.G. ; Gemmecker, G. ; Aichler, M. ; Mettenleiter, G. ; Schulz, M. ; Walch, A.K. ; Hrabě de Angelis, M. ; Feige, M.J. ; Sierra, C.A. ; Conrad, M. ; Tripsianes, K. ; Ramamoorthy, A. ; Reif, B.
hIAPP forms toxic oligomers in plasma.Sigmund, F. ; Massner, C. ; Erdmann, P. ; Stelzl, A. ; Rolbieski, H. ; Desai, M. ; Bricault, S. ; Wörner, T.P. ; Snijder, J. ; Geerlof, A. ; Fuchs, H. ; Hrabě de Angelis, M. ; Heck, A.J.R. ; Jasanoff, A. ; Ntziachristos, V. ; Plitzko, J. ; Westmeyer, G.G.
Bacterial encapsulins as orthogonal compartments for mammalian cell engineering.Torres-Mejia, E.
Identification of Sox2 as a key regulator of cell-matrix adhesion in Schwann cells.Chen, Y. ; Liu, Y. ; Lan, T.H. ; Qin, W. ; Zhu, Y. ; Qin, K. ; Gao, J. ; Wang, H. ; Hou, X. ; Chen, N. ; Friedmann Angeli, J.P.F. ; Conrad, M. ; Wang, C.
Quantitative profiling of protein carbonylations in ferroptosis by an aniline-derived probe.André, V. ; Gau, C. ; Scheideler, A. ; Aguilar-Pimentel, J.A. ; Amarie, O.V. ; Becker, L. ; Garrett, L. ; Hans, W. ; Hölter, S.M. ; Janik, D. ; Moreth, K. ; Neff, F. ; Östereicher, M.A. ; Rácz, I. ; Rathkolb, B. ; Rozman, J. ; Bekeredjian, R. ; Graw, J. ; Klingenspor, M. ; Klopstock, T. ; Ollert, M. ; Schmidt-Weber, C.B. ; Wolf, E. ; Wurst, W. ; Gailus-Durner, V. ; Brielmeier, M. ; Fuchs, H. ; Hrabě de Angelis, M.
Laboratory mouse housing conditions can be improved using common environmental enrichment without compromising data.Bartsch, K. ; Damme, M. ; Regen, T. ; Becker, L. ; Garrett, L. ; Hölter, S.M. ; Knittler, K. ; Borowski, C. ; Waisman, A. ; Glatzel, M. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Rabe, B.
RNase H2 loss in murine astrocytes results in cellular defects reminiscent of nucleic acid-mediated autoinflammation.Zimprich, A. ; Wurst, W. ; Trümbach, D. ; Rozman, J. ; Hrabě de Angelis, M. ; Hölter, S.M. ; Garrett, L. ; Gailus-Durner, V. ; Fuchs, H. ; Becker, L. ; Vogt Weisenhorn, D.M. ; Miller, G.
Identifying underlying mechanisms of voluntary activity by mining large data sets of genetically modified mouse lines.Alwin Prem Anand, A. ; Huber, C. ; Asnet Mary, J. ; Gallus, N. ; Leucht, C. ; Klafke, R. ; Hirt, B. ; Wizenmann, A.
Expression and function of microRNA-9 in the mid-hindbrain area of embryonic chick.Galluzzi, L. ; Vitale, I. ; Aaronson, S.A. ; Abrams, J.M. ; Adam, D. ; Agostinis, P. ; Alnemri, E.S. ; Altucci, L. ; Amelio, I. ; Andrews, D.W. ; Annicchiarico-Petruzzelli, M. ; Antonov, A.V. ; Arama, E. ; Baehrecke, E.H. ; Barlev, N.A. ; Bazan, N.G. ; Bernassola, F. ; Bertrand, M.J.M. ; Bianchi, K. ; Blagosklonny, M.V. ; Blomgren, K. ; Borner, C. ; Boya, P. ; Brenner, C.D. ; Campanella, M. ; Candi, E. ; Carmona-Gutierrez, D. ; Cecconi, F. ; Chan, F.K. ; Chandel, N.S. ; Cheng, E.H. ; Chipuk, J.E. ; Cidlowski, J.A. ; Ciechanover, A. ; Cohen, G.M. ; Conrad, M. ; Cubillos-Ruiz, J.R. ; Czabotar, P.E. ; D'Angiolella, V. ; Dawson, T.M. ; Dawson, V.L. ; De Laurenzi, V. ; de Maria, R. ; Debatin, K.M. ; DeBerardinis, R.J. ; Deshmukh, M. ; Di Daniele, N. ; Di Virgilio, F. ; Dixit, V.M. ; Dixon, S.J. ; Duckett, C.S. ; Dynlacht, B.D. ; El-Deiry, W.S. ; Elrod, J.W. ; Fimia, G.M. ; Fulda, S. ; García-Sáez, A.J. ; Garg, A.D. ; Garrido, C. ; Gavathiotis, E. ; Golstein, P. ; Gottlieb, E. ; Green, D.R. ; Greene, L.A. ; Gronemeyer, H. ; Gross, A. ; Hajnoczky, G. ; Hardwick, J.M. ; Harris, I.S. ; Hengartner, M.O. ; Hetz, C. ; Ichijo, H. ; Jäättelä, M. ; Joseph, B. ; Jost, P.J. ; Juin, P.P. ; Kaiser, W.J. ; Karin, M. ; Kaufmann, T. ; Kepp, O. ; Kimchi, A. ; Kitsis, R.N. ; Klionsky, D.J. ; Knight, R.A. ; Kumar, S. ; Lee, S.W. ; Lemasters, J.J. ; Levine, B. ; Linkermann, A. ; Lipton, S.A. ; Lockshin, R.A. ; López-Otín, C. ; Lowe, S.W. ; Luedde, T. ; Lugli, E. ; MacFarlane, M. ; Madeo, F. ; Malewicz, M. ; Malorni, W. ; Manic, G. ; Marine, J.C. ; Martin, S.J. ; Martinou, J.C. ; Medema, J.P. ; Mehlen, P. ; Meier, P.J. ; Melino, S. ; Miao, E.A. ; Molkentin, J.D. ; Moll, U.M. ; Muñoz-Pinedo, C. ; Nagata, S. ; Nuñez, G. ; Oberst, A. ; Oren, M. ; Overholtzer, M. ; Pagano, M. ; Panaretakis, T. ; Pasparakis, M. ; Penninger, J.M. ; Pereira, D.M. ; Pervaiz, S. ; Peter, M.E. ; Piacentini, M. ; Pinton, P. ; Prehn, J.H.M. ; Puthalakath, H. ; Rabinovich, G.A. ; Rehm, M. ; Rizzuto, R. ; Rodrigues, C.M.P. ; Rubinsztein, D.C. ; Rudel, T. ; Ryan, K.M. ; Sayan, E. ; Scorrano, L. ; Shao, F.W. ; Shi, Y. ; Silke, J. ; Simon, H.U. ; Sistigu, A. ; Stockwell, B.R. ; Strasser, A. ; Szabadkai, G. ; Tait, S.W.G. ; Tang, D. ; Tavernarakis, N. ; Thorburn, A. ; Tsujimoto, Y. ; Turk, B. ; Vanden Berghe, T. ; Vandenabeele, P. ; Vander Heiden, M.G. ; Villunger, A. ; Virgin, H.W. ; Vousden, K.H. ; Vucic, D. ; Wagner, E.F. ; Walczak, H. ; Wallach, D. ; Wang, Y. ; Wells, J.A. ; Wood, W. ; Yuan, J. ; Zakeri, Z. ; Zhivotovsky, B. ; Zitvogel, L. ; Melino, G. ; Kroemer, G.
Molecular mechanisms of cell death: Recommendations of the Nomenclature Committee on Cell Death 2018.Massner, C. ; Sigmund, F. ; Pettinger, S. ; Seeger, M. ; Hartmann, C. ; Ivleva, N.P. ; Niessner, R. ; Fuchs, H. ; Hrabě de Angelis, M. ; Stelzl, A. ; Koonakampully, N.L. ; Rolbieski, H. ; Wiedwald, U. ; Spasova, M. ; Wurst, W. ; Ntziachristos, V. ; Winklhofer, M. ; Westmeyer, G.G.
Genetically controlled lysosomal entrapment of superparamagnetic ferritin for multimodal and multiscale imaging and actuation with low tissue attenuation.Sato, M. ; Kusumi, R. ; Hamashima, S. ; Kobayashi, S. ; Sasaki, S. ; Komiyama, Y. ; Izumikawa, T. ; Conrad, M. ; Bannai, S. ; Sato, H.
The ferroptosis inducer erastin irreversibly inhibits system xc- and synergizes with cisplatin to increase cisplatin's cytotoxicity in cancer cells.Rozman, J. ; Rathkolb, B. ; Oestereicher, M.A. ; Schütt, C. ; Ravindranath, A.C. ; Leuchtenberger, S. ; Sharma, S. ; Kistler, M. ; Willershäuser, M. ; Brommage, R. ; Meehan, T.F. ; Mason, J. ; Haselimashhadi, H. ; Hough, T. ; Mallon, A.-M. ; Wells, S. ; Santos, L. ; Lelliott, C.J. ; White, J.K. ; Sorg, T. ; Champy, M.-F. ; Bower, L.R. ; Reynolds, C.L. ; Flenniken, A.M. ; Murray, S.A. ; Nutter, L.M.J. ; Svenson, K.L. ; West, D. ; Tocchini-Valentini, G.P. ; Beaudet, A.L. ; Bosch, F. ; Braun, R.B. ; Dobbie, M.S. ; Gao, X. ; Herault, Y. ; Moshiri, A. ; Moore, B.A. ; Kent Lloyd, K.C. ; McKerlie, C. ; Masuya, H. ; Tanaka, N. ; Flicek, P. ; Parkinson, H.E. ; Sedlacek, R. ; Seong, J.K. ; Wang, C.-K.L. ; Moore, M. ; Brown, S.D. ; Tschöp, M.H. ; Wurst, W. ; Klingenspor, M. ; Wolf, E. ; Beckers, J. ; Machicao, F. ; Peter, A. ; Staiger, H. ; Häring, H.-U. ; Grallert, H. ; Campillos, M. ; Maier, H. ; Fuchs, H. ; Gailus-Durner, V. ; Werner, T. ; Hrabě de Angelis, M. ; IMPC Consortium (Eickelberg, O.) ; IMPC Consortium (Yildirim, A.Ö.)
Identification of genetic elements in metabolism by high-throughput mouse phenotyping.Myklatun, A. ; Lauri, A. ; Eder, S.H.K. ; Cappetta, M. ; Shcherbakov, D. ; Wurst, W. ; Winklhofer, M. ; Westmeyer, G.G.
Zebrafish and medaka offer insights into the neurobehavioral correlates of vertebrate magnetoreception.Dalke, C. ; Neff, F. ; Bains, S.K. ; Bright, S. ; Lord, D.J. ; Reitmeir, P. ; Rößler, U. ; Samaga, D. ; Unger, K. ; Braselmann, H. ; Wagner, F. ; Greiter, M. ; Gomolka, M. ; Hornhardt, S. ; Kunze, S. ; Kempf, S.J. ; Garrett, L. ; Hölter, S.M. ; Wurst, W. ; Rosemann, M. ; Azimzadeh, O. ; Tapio, S. ; Aubele, M. ; Theis, F.J. ; Hoeschen, C. ; Slijepcevic, P. ; Kadhim, M. ; Atkinson, M.J. ; Zitzelsberger, H. ; Kulka, U. ; Graw, J.
Lifetime study in mice after acute low-dose ionizing radiation: A multifactorial study with special focus on cataract risk.Li, Z.M. ; Giesert, F. ; Vogt Weisenhorn, D.M. ; Main, K.M. ; Skakkebæk, N.E. ; Kiviranta, H. ; Toppari, J. ; Feldt-Rasmussen, U. ; Shen, H. ; Schramm, K.-W. ; de Angelis, M.
Determination of thyroid hormones in placenta using isotope-dilution liquid chromatography quadrupole time-of-flight mass spectrometry.Ingold, I. ; Berndt, C. ; Schmitt, S. ; Doll, S. ; Poschmann, G. ; Buday, K. ; Roveri, A. ; Peng, X. ; Porto Freitas, F. ; Seibt, T. ; Mehr, L. ; Aichler, M. ; Walch, A.K. ; Lamp, D. ; Jastroch, M. ; Miyamoto, S. ; Wurst, W. ; Ursini, F. ; Arnér, E.S.J. ; Fradejas-Villar, N. ; Schweizer, U. ; Zischka, H. ; Friedmann Angeli, J.P.F. ; Conrad, M.
Selenium utilization by GPX4 is required to prevent hydroperoxide-induced ferroptosis.Kunze, C. ; Börner, K. ; Kienle, E. ; Orschmann, T. ; Rusha, E. ; Schneider, M. ; Radivojkov-Blagojevic, M. ; Drukker, M. ; Desbordes, S.C. ; Grimm, D. ; Brack-Werner, R.
Synthetic AAV/CRISPR vectors for blocking HIV-1 expression in persistently infected astrocytes.Egea, J. ; Fabregat, I. ; Frapart, Y.M. ; Ghezzi, P. ; Görlach, A. ; Kietzmann, T. ; Kubaichuk, K. ; Knaus, U.G. ; Lopez, M.G. ; Olaso-Gonzalez, G. ; Petry, A. ; Schulz, R. ; Vina, J. ; Winyard, P. ; Abbas, K. ; Ademowo, O.S. ; Afonso, C.B. ; Andreadou, I. ; Antelmann, H. ; Antunes, F. ; Aslan, M. ; Bachschmid, M.M. ; Barbosa, R.M. ; Belousov, V. ; Berndt, C. ; Bernlohr, D. ; Bertrán, E. ; Bindoli, A. ; Bottari, S.P. ; Brito, P.M. ; Carrara, G. ; Casas, A.I. ; Chatzi, A. ; Chondrogianni, N. ; Conrad, M. ; Cooke, M.S. ; Costa, J.G. ; Cuadrado, A. ; My-Chan Dang, P. ; De Smet, B. ; Debelec-Butuner, B. ; Dias, I.H.K. ; Dunn, J.D. ; Edson, A.J. ; El Assar, M. ; El-Benna, J. ; Ferdinandy, P. ; Fernandes, A.S. ; Fladmark, K.E. ; Förstermann, U. ; Giniatullin, R. ; Giricz, Z. ; Görbe, A. ; Griffiths, H. ; Hampl, V. ; Hanf, A. ; Herget, J. ; Hernansanz-Agustín, P. ; Hillion, M. ; Huang, J. ; Ilikay, S. ; Jansen-Dürr, P. ; Jaquet, V. ; Joles, J.A. ; Kalyanaraman, B. ; Kaminskyy, D. ; Karbaschi, M. ; Kleanthous, M. ; Klotz, L.O. ; Korac, B. ; Korkmaz, K.S. ; Koziel, R. ; Kračun, D. ; Krause, K.H. ; Křen, V. ; Krieg, T. ; Laranjinha, J. ; Lazou, A. ; Li, H. ; Martínez-Ruiz, A. ; Matsui, R. ; McBean, G.J. ; Meredith, S.P. ; Messens, J. ; Miguel, V. ; Mikhed, Y. ; Milisav, I. ; Milković, L. ; Miranda-Vizuete, A. ; Mojović, M. ; Monsalve, M. ; Mouthuy, P.A. ; Mulvey, J. ; Münzel, T. ; Muzykantov, V. ; Nguyen, I.T.N. ; Oelze, M. ; Oliveira, N.G. ; Palmeira, C.M. ; Papaevgeniou, N.
European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS) (vol 13, pg 94, 2017).Roberts, S. ; Seeger, M. ; Jiang, Y. ; Mishra, A. ; Sigmund, F. ; Stelzl, A. ; Lauri, A. ; Symvoulidis, P. ; Rolbieski, H. ; Preller, M. ; Dean-Ben, X.L. ; Razansky, D. ; Orschmann, T. ; Desbordes, S.C. ; Vetschera, P. ; Bach, T. ; Ntziachristos, V. ; Westmeyer, G.G.
Calcium sensor for photoacoustic imaging.Dedic, N. ; Pöhlmann, M.L. ; Richter, J.S. ; Mehta, D. ; Czamara, D. ; Metzger, M.W. ; Dine, J. ; Bedenk, B.T. ; Hartmann, J. ; Wagner, K.V. ; Jurik, A. ; Almli, L.M. ; Lori, A. ; Moosmang, S. ; Hofmann, F. ; Wotjak, C.T. ; Rammes, G. ; Eder, M. ; Chen, A. ; Ressler, K.J. ; Wurst, W. ; Schmidt, M.V. ; Binder, E.B. ; Deussing, J.M.
Cross-disorder risk gene CACNA1C differentially modulates susceptibility to psychiatric disorders during development and adulthood.Neu, E. ; Michailov, M.C. ; Foltin, V. ; Senn, T. ; Welscher, U. ; Foltinova, J. ; Graw, J. ; Hofstetter, A. ; Hohlbrugger, G. ; Madersbacher, H. ; Weissenbacher, E.R. ; Weiss, D.G.
On importance of pathophysiology for an integrative toxicology.Dickinson, M.E. ; Flenniken, A.M. ; Ji, X. ; Teboul, L. ; Wong, M.D. ; White, J.K. ; Meehan, T.F. ; Weninger, W.J. ; Westerberg, H. ; Adissu, H.A. ; Baker, C.N. ; Bower, L. ; Brown, J.M. ; Caddle, L.B. ; Chiani, F. ; Clary, D. ; Cleak, J. ; Daly, M.J. ; Denegre, J.M. ; Doe, B. ; Dolan, M.E. ; Edie, S.M. ; Fuchs, H. ; Gailus-Durner, V. ; Galli, A. ; Gambadoro, A. ; Gallegos, J. ; Guo, S. ; Horner, N.R. ; Hsu, C.-W. ; Johnson, S.J. ; Kalaga, S. ; Keith, L.C. ; Lanoue, L. ; Lawson, T.N. ; Lek, M. ; Mark, M. ; Marschall, S. ; Mason, J. ; McElwee, M.L. ; Newbigging, S. ; Nutter, L.M.J. ; Peterson, K.A. ; Ramirez-Solis, R. ; Rowland, D.J. ; Ryder, E. ; Samocha, K.E. ; Seavitt, J.R. ; Selloum, M. ; Szoke-Kovacs, Z. ; Tamura, M. ; Trainor, A.G. ; Tudose, I. ; Wakana, S. ; Warren, J. ; Wendling, O. ; West, D.B. ; Wong, L. ; Yoshiki, A. ; Wurst, W. ; MacArthur, D.G. ; Tocchini-Valentini, G.P. ; Gao, X. ; Flicek, P. ; Bradley, A. ; Skarnes, W.C. ; Justice, M.J. ; Parkinson, H.E. ; Moore, M. ; Wells, S. ; Braun, R.E. ; Svenson, K.L. ; Hrabě de Angelis, M. ; Herault, Y. ; Mohun, T. ; Mallon, A.M. ; Henkelman, R.M. ; Brown, S.D.M. ; Adams, D.J. ; Lloyd, K.C.K. ; McKerlie, C. ; Beaudet, A.L. ; Bućan, M. ; Murray, S.A.
Corrigendum: High-throughput discovery of novel developmental phenotypes.Beckervordersandforth, R. ; Ebert, B. ; Schäffner, I. ; Moss, J. ; Fiebig, C. ; Shin, J. ; Moore, D.L. ; Ghosh, L. ; Trinchero, M.F. ; Stockburger, C. ; Friedland, K. ; Steib, K. ; von Wittgenstein, J. ; Keiner, S. ; Redecker, C. ; Hölter, S.M. ; Xiang, W. ; Wurst, W. ; Jagasia, R. ; Schinder, A.F. ; Ming, G.l. ; Toni, N. ; Jessberger, S. ; Song, H. ; Lie, D.C.C.
Role of mitochondrial metabolism in the control of early lineage progression and aging phenotypes in adult hippocampal neurogenesis.Zimprich, A. ; Niessing, J. ; Cohen, L. ; Garrett, L. ; Einicke, J. ; Sperling, B. ; Schmidt, M.V. ; Hölter, S.M.
Assessing sociability, social memory, and pup retrieval in mice.Metzger, M.W. ; Walser, S.M. ; Dedic, N. ; Aprile-Garcia, F. ; Jakubcakova, V. ; Adamczyk, M. ; Webb, K.J. ; Uhr, M. ; Refojo, D. ; Schmidt, M.V. ; Friess, E. ; Steiger, A. ; Kimura, M. ; Chen, A. ; Holsboer, F. ; Arzt, E. ; Wurst, W. ; Deussing, J.M.
Heterozygosity for the mood disorder-associated variant Gln460Arg alters P2X7 receptor function and sleep quality.Ingold, I. ; Berndt, C. ; Schmitt, S. ; Doll, S. ; Poschmann, G. ; Roveri, A. ; Peng, X. ; Freitas, F.P. ; Aichler, M. ; Jastroch, M. ; Ursini, F. ; Arner, E.S.J. ; Fradejas-Villar, N. ; Schweizer, U. ; Zischka, H. ; Friedmann Angeli, J.P.F. ; Conrad, M.
Selenium utilization by GPX4 was an evolutionary requirement to prevent hydroperoxide-induced ferroptosis.Trümbach, D. ; Pfeiffer, S. ; Poppe, M. ; Scherb, H. ; Doll, S. ; Wurst, W. ; Schick, J.
ENCoRE: An efficient software for CRISPR screens identifies new players in extrinsic apoptosis.Egaña, I. ; Kaito, H. ; Nitzsche, A. ; Becker, L. ; Ballester-Lopez, C. ; Niaudet, C. ; Petkova, M. ; Liu, W. ; Vandlandewijck, M. ; Vernaleken, A. ; Klopstock, T. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Rask-Andersen, H. ; Johansson, H.J. ; Lehtiö, J. ; He, L. ; Yildirim, A.Ö. ; Hellström, M. ; German Mouse Clinic Consortium (Aguilar-Pimentel, J.A. ; Ollert, M. ; Schmidt-Weber, C.B. ; Amarie, O.V. ; Graw, J. ; Beckers, J. ; Garrett, L. ; Hölter, S.M. ; Zimprich, A. ; Wurst, W. ; Moreth, K. ; Bekeredjian, R. ; Neff, F. ; Calzada-Wack, J. ; Rácz, I. ; Zimmer, A. ; Rathkolb, B. ; Wolf, E. ; Rozman, J. ; Klingenspor, M. ; Stöger, T. ; Eickelberg, O. ; Treise, I. ; Busch, D.H. ; Östereicher, M.A. ; Steinkamp, R. ; Lengger, C. ; Maier, H. ; Stoeger, C. ; Leuchtenberger, S.)
Female mice lacking Pald1 exhibit endothelial cell apoptosis and emphysema.Eggenhofer, E. ; Proneth, B. ; Doll, S. ; Conrad, M. ; Schlitt, H. ; Geissler, E.K.
Interaction of innate immune cells and regulated cell death in early hepatic ischemia reperfusion injury.Bowl, M.R. ; Simon, M.M. ; Ingham, N.J. ; Greenaway, S. ; Santos, L. ; Cater, H. ; Taylor, S. ; Mason, J. ; Kurbatova, N. ; Pearson, S. ; Bower, L.R. ; Clary, D. ; Meziane, H. ; Reilly, P. ; Minowa, O. ; Kelsey, L. ; Tocchini-Valentini, G.P. ; Gao, X. ; Bradley, A. ; Skarnes, W.C. ; Moore, M. ; Beaudet, A.L. ; Justice, M.J. ; Seavitt, J.R. ; Dickinson, M.E. ; Wurst, W. ; Hrabě de Angelis, M. ; Herault, Y. ; Wakana, S. ; Nutter, L.M.J. ; Flenniken, A.M. ; McKerlie, C. ; Murray, S.A. ; Svenson, K.L. ; Braun, R.E. ; West, D.B. ; Llyod, K.C.K. ; Adams, D.J. ; White, J. ; Karp, N. ; Flicek, P. ; Smedley, D. ; Meehan, T.F. ; Parkinson, H.E. ; Teboul, L. ; Wells, S. ; Steel, K.P. ; Mallon, A.M. ; Brown, S.D. ; International Mouse Phenotyping Consortium (Beig, J. ; Bürger, A. ; Giesert, F. ; Graw, J. ; Kühn, R. ; Oritz, O. ; Schick, J. ; Seisenberger, C. ; Amarie, O.V. ; Garrett, L. ; Hölter, S.M. ; Zimprich, A. ; Aguilar-Pimentel, J.A. ; Beckers, J. ; Brommage, R. ; Calzada-Wack, J. ; Fuchs, H. ; Gailus-Durner, V. ; Lengger, C. ; Leuchtenberger, S. ; Maier, H. ; Marschall, S. ; Moreth, K. ; Neff, F. ; Östereicher, M.A. ; Rozman, J. ; Steinkamp, R. ; Stoeger, C. ; Treise, I. ; Stöger, T. ; Yildirim, A.Ö. ; Becker, L. ; Rathkolb, B. ; Eickelberg, O. ; Schmidt-Weber, C.B.)
A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction.Stockwell, B.R. ; Friedmann Angeli, J.P.F. ; Bayir, H. ; Bush, A.I. ; Conrad, M. ; Dixon, S.J. ; Fulda, S. ; Gascón, S. ; Hatzios, S.K. ; Kagan, V.E. ; Noel, K. ; Jiang, X. ; Linkermann, A. ; Murphy, M.E. ; Overholtzer, M. ; Oyagi, A. ; Pagnussat, G.C. ; Park, J. ; Ran, Q. ; Rosenfeld, C.S. ; Salnikow, K. ; Tang, D. ; Torti, F.M. ; Torti, S.V. ; Toyokuni, S. ; Woerpel, K.A. ; Zhang, D.D.
Ferroptosis: A regulated cell death nexus linking metabolism, redox biology, and disease.Symvoulidis, P. ; Lauri, A. ; Stefanoiu, A. ; Cappetta, M. ; Schneider, S. ; Jia, H. ; Stelzl, A. ; Koch, M. ; Perez, C.C. ; Myklatun, A. ; Renninger, S. ; Chmyrov, A. ; Lasser, T. ; Wurst, W. ; Ntziachristos, V. ; Westmeyer, G.G.
NeuBtracker-imaging neurobehavioral dynamics in freely behaving fish.Fuchs, H. ; Aguilar-Pimentel, A. ; Amarie, O.V. ; Becker, L. ; Calzada-Wack, J. ; Cho, Y.-L. ; Garrett, L. ; Hölter, S.M. ; Irmler, M. ; Kistler, M. ; Kraiger, M. ; Mayer-Kuckuk, P. ; Moreth, K. ; Rathkolb, B. ; Rozman, J. ; da Silva Buttkus, P. ; Treise, I. ; Zimprich, A. ; Gampe, K. ; Hutterer, C. ; Leuchtenberger, S. ; Maier, H. ; Miller, M. ; Scheideler, A. ; Wu, M. ; Beckers, J. ; Bekeredjian, R. ; Brielmeier, M. ; Busch, D.H. ; Klingenspor, M. ; Klopstock, T. ; Ollert, M. ; Schmidt-Weber, C.B. ; Stöger, T. ; Wolf, E. ; Wurst, W. ; Yildirim, A.Ö. ; Zimmer, A. ; Gailus-Durner, V. ; Hrabě de Angelis, M.
Understanding gene functions and disease mechanisms: Phenotyping pipelines in the German Mouse Clinic.Kaloff, C. ; Anastassiadis, K. ; Ayadi, A. ; Baldock, R. ; Beig, J. ; Birling, M.C. ; Bradley, A. ; Brown, S.D.M. ; Bürger, A. ; Bushell, W. ; Chiani, F. ; Collins, F.S. ; Doe, B. ; Eppig, J.T. ; Finnell, R.H. ; Fletcher, C. ; Flicek, P. ; Fray, M. ; Friedel, R.H. ; Gambadoro, A. ; Gates, H. ; Hansen, J. ; Herault, Y. ; Hicks, G.G. ; Hörlein, A. ; Hrabě de Angelis, M. ; Iyer, V. ; de Jong, P.J. ; Koscielny, G. ; Kühn, R. ; Liu, P. ; Lloyd, K.C.K. ; Lopez, R.G. ; Marschall, S. ; Martínez, S. ; McKerlie, C. ; Meehan, T.F. ; von Melchner, H. ; Moore, M. ; Murray, S.A. ; Nagy, A. ; Nutter, L.M.J. ; Pavlovic, G. ; Pombero, A. ; Prosser, H. ; Ramirez-Solis, R. ; Ringwald, M. ; Rosen, B. ; Rosenthal, N. ; Rossant, J. ; Ruiz Noppinger, P. ; Ryder, E. ; Skarnes, W.C. ; Schick, J. ; Schnütgen, F. ; Schofield, P. ; Seisenberger, C. ; Selloum, M. ; Smedley, D. ; Simpson, E.M. ; Stewart, A.F. ; Teboul, L. ; Tocchini Valentini, G.P. ; Valenzuela, D. ; West, A.P. ; Wurst, W.
Genome wide conditional mouse knockout resources.Drefs, M. ; Thomas, M.N. ; Guba, M. ; Angele, M.K. ; Werner, J. ; Conrad, M. ; Steib, C.J. ; Holdt, L.M. ; Andrassy, J. ; Khandoga, A. ; Rentsch, M.
Modulation of glutathione hemostasis by inhibition of 12/15-lipoxygenase prevents ROS-mediated cell death after hepatic ischemia and reperfusion.Kumar, S. ; Rathkolb, B. ; Sabrautzki, S. ; Krebs, S. ; Kemter, E. ; Becker, L. ; Beckers, J. ; Bekeredjian, R. ; Brommage, R. ; Calzada-Wack, J. ; Garrett, L. ; Hölter, S.M. ; Horsch, M. ; Klingenspor, M. ; Klopstock, T. ; Moreth, K. ; Neff, F. ; Rozman, J. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Wolf, E. ; Aigner, B.
Standardized, systemic phenotypic analysis reveals kidney dysfunction as main alteration of Kctd1I27N mutant mice.Danner, E. ; Bashir, S. ; Yumlu, S. ; Wurst, W. ; Wefers, B. ; Kuehn, R.
Control of gene editing by manipulation of DNA repair mechanisms.Mao, G. ; Qu, F. ; Angell, J.P. ; St Croix, C. ; Dar, H.H. ; Tyurin, V.A. ; Ritov, V.B. ; Kapralov, A.A. ; Amoscato, A.A. ; Anthonymuthu, T. ; Mohammadyani, D. ; Yang, Q. ; Stockwell, B.R. ; Tyurina, Y.Y. ; Conrad, M. ; Bayir, H. ; Kagan, V.E.
Tocopherols and tocotrienols prevent lipoxygenase-driven phospholipid oxidation in ferroptosis.Xie, K. ; Neff, F. ; Markert, A. ; Rozman, J. ; Aguilar-Pimentel, A. ; Amarie, O.V. ; Becker, L. ; Brommage, R. ; Garrett, L. ; Henzel, K.S. ; Hölter, S.M. ; Janik, D. ; Lehmann, I. ; Moreth, K. ; Pearson, B.L. ; Rácz, I. ; Rathkolb, B. ; Ryan, D.P. ; Schröder, S. ; Treise, I. ; Bekeredjian, R. ; Busch, D.H. ; Graw, J. ; Ehninger, G. ; Klingenspor, M. ; Klopstock, T. ; Ollert, M. ; Sandholzer, M. ; Schmidt-Weber, C.B. ; Weiergräber, M. ; Wolf, E. ; Wurst, W. ; Zimmer, A. ; Gailus-Durner, V. ; Fuchs, H. ; Hrabě de Angelis, M. ; Ehninger, D.
Every-other-day feeding extends lifespan but fails to delay many symptoms of aging in mice.Weiß, S.J.A.
The role of Glypican 4 during mouse brain development.Meehan, T.F. ; Conte, N. ; West, D.B. ; Jacobsen, J.O. ; Mason, J. ; Warren, J. ; Chen, C.K. ; Tudose, I. ; Relac, M. ; Matthews, P. ; Karp, N. ; Santos, L. ; Fiegel, T. ; Ring, N. ; Westerberg, H. ; Greenaway, S. ; Sneddon, D. ; Morgan, H. ; Codner, G.F. ; Stewart, M.E. ; Brown, J. ; Horner, N.R. ; Haendel, M. ; Washington, N. ; Mungall, C.J. ; Reynolds, C.L. ; Gallegos, J. ; Gailus-Durner, V. ; Sorg, T. ; Pavlovic, G. ; Bower, L.R. ; Moore, M. ; Morse, I. ; Gao, X. ; Tocchini-Valentini, G.P. ; Obata, Y. ; Cho, S.Y. ; Seong, J.K. ; Seavitt, J.R. ; Beaudet, A.L. ; Dickinson, M.E. ; Herault, Y. ; Wurst, W. ; Hrabě de Angelis, M. ; Lloyd, K.C.K. ; Flenniken, A.M. ; Nutter, L.M.J. ; Newbigging, S. ; McKerlie, C. ; Justice, M.J. ; Murray, S.A. ; Svenson, K.L. ; Braun, R.E. ; White, J.K. ; Bradley, A. ; Flicek, P. ; Wells, S. ; Skarnes, W.C. ; Adams, D.J. ; Parkinson, H. ; Mallon, A.M. ; Brown, S.D.M. ; Smedley, D.
Disease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium.Salminen, A.V. ; Garrett, L. ; Schormair, B. ; Rozman, J. ; Giesert, F. ; Niedermeier, K.M. ; Becker, L. ; Rathkolb, B. ; Rácz, I. ; Klingenspor, M. ; Klopstock, T. ; Wolf, E. ; Zimmer, A. ; Gailus-Durner, V. ; Torres, M. ; Fuchs, H. ; Hrabě de Angelis, M. ; Wurst, W. ; Hölter, S.M. ; Winkelmann, J.
Meis1 effects on motor phenotypes and the sensorimotor system in mice.Wefers, B. ; Bashir, S. ; Rossius, J. ; Wurst, W. ; Kühn, R.
Gene editing in mouse zygotes using the CRISPR/Cas9 system.Zhang, D. ; Wu, B.L. ; Wang, P. ; Wang, Y. ; Lu, P. ; Nechiporuk, T. ; Floß, T. ; Greally, J.M. ; Zheng, D. ; Zhou, B.
Non-CpG methylation by DNMT3B facilitates REST binding and gene silencing in developing mouse hearts.Altamura, S. ; Vegi, N. ; Hueltner, L. ; Schneider, M. ; Höppe, P. ; Schroeder, T. ; Canli, Ö. ; Greten, F.R. ; Aichler, M. ; Walch, A.K. ; Neff, F. ; Janik, D. ; Kuklik-Roos, C. ; Ladinig, C. ; Mysliwietz, J. ; Rathkolb, B. ; Buske, C. ; Conrad, M. ; Muckenthaler, M.U. ; Bornkamm, G.W.
Lack of the ferroptosis inhibitor GPX4 in erythroid cells causes a block in reticulocyte maturation and a hypoxic signature with impaired hepcidin regulation.Dirscherl, P. ; Jastroch, M. ; Vogt-Weisenhorn, D. ; Wurst, W.
Mitochondrial function in Pink1 deficient astrocytes.Garrett, L. ; Becker, L. ; Rozman, J. ; Puk, O. ; Stöger, T. ; Yildirim, A.Ö. ; Bohla, A. ; Eickelberg, O. ; Hans, W. ; Prehn, C. ; Adamski, J. ; Klopstock, T. ; Rácz, I. ; Zimmer, A. ; Klingenspor, M. ; Fuchs, H. ; Gailus-Durner, V. ; Wurst, W. ; Hrabě de Angelis, M. ; Graw, J. ; Hölter, S.M.
Fgf9Y162C mutation alters information processing and social memory in mice.Biagosch, C. ; Ediga, R. ; Hensler, S. ; Faerberboeck, M. ; Kühn, R. ; Wurst, W. ; Meitinger, T. ; Kölker, S. ; Sauer, S. ; Prokisch, H.
Elevated glutaric acid levels in Dhtkd1-/Gcdh- double knockout mice challenge our current understanding of lysine metabolism.Egea, J. ; Fabregat, I. ; Frapart, Y.M. ; Ghezzi, P. ; Görlach, A. ; Kietzmann, T. ; Kubaichuk, K. ; Knaus, U.G. ; Lopez, M.G. ; Olaso-Gonzalez, G. ; Petry, A. ; Schulz, R. ; Vina, J. ; Winyard, P. ; Abbas, K. ; Ademowo, O.S. ; Afonso, C.B. ; Andreadou, I. ; Antelmann, H. ; Antunes, F. ; Aslan, M. ; Bachschmid, M.M. ; Barbosa, R.M. ; Belousov, V. ; Berndt, C. ; Bernlohr, D. ; Bertrán, E. ; Bindoli, A. ; Bottari, S.P. ; Brito, P.M. ; Carrara, G. ; Casas, A.I. ; Chatzi, A. ; Chondrogianni, N. ; Conrad, M. ; Cooke, M.S. ; Costa, J.G. ; Cuadrado, A. ; My-Chan Dang, P. ; De Smet, B. ; Debelec-Butuner, B. ; Dias, I.H.K. ; Dunn, J.D. ; Edson, A.J. ; El Assar, M. ; El-Benna, J. ; Ferdinandy, P. ; Fernandes, A.S. ; Fladmark, K.E. ; Förstermann, U. ; Giniatullin, R. ; Giricz, Z. ; Görbe, A. ; Griffiths, H. ; Hampl, V. ; Hanf, A. ; Herget, J. ; Hernansanz-Agustín, P. ; Hillion, M. ; Huang, J. ; Ilikay, S. ; Jansen-Dürr, P. ; Jaquet, V. ; Joles, J.A. ; Kalyanaraman, B. ; Kaminskyy, D. ; Karbaschi, M. ; Kleanthous, M. ; Klotz, L.O. ; Korac, B. ; Korkmaz, K.S. ; Koziel, R. ; Kračun, D. ; Krause, K.H. ; Křen, V. ; Krieg, T. ; Laranjinha, J. ; Lazou, A. ; Li, H. ; Martínez-Ruiz, A. ; Matsui, R. ; McBean, G.J. ; Meredith, S.P. ; Messens, J. ; Miguel, V. ; Mikhed, Y. ; Milisav, I. ; Milković, L. ; Miranda-Vizuete, A. ; Mojović, M. ; Monsalve, M. ; Mouthuy, P.A. ; Mulvey, J. ; Münzel, T. ; Muzykantov, V. ; Nguyen, I.T.N. ; Oelze, M. ; Oliveira, N.G. ; Palmeira, C.M. ; Papaevgeniou, N. ; Pavićević, A. ; Pedre, B. ; Peyrot, F. ; Phylactides, M. ; Pircalabioru, G.G. ; Pitt, A.R. ; Poulsen, H.E. ; Prieto, I. ; Rigobello, M.P. ; Robledinos-Antón, N. ; Rodríguez-Mañas, L. ; Rolo, A.P. ; Rousset, F. ; Ruskovska, T. ; Saraiva, N. ; Sasson, S. ; Schröder, K. ; Semen, K. ; Seredenina, T. ; Shakirzyanova, A. ; Smith, G.L. ; Soldati, T. ; Sousa, B.C. ; Spickett, C.M. ; Stancic, A. ; Stasia, M.J. ; Steinbrenner, H. ; Stepanić, V. ; Steven, S. ; Tokatlidis, K. ; Tuncay, E. ; Turan, B. ; Ursini, F. ; Vacek, J. ; Vajnerova, O. ; Valentová, K. ; van Breusegem, F. ; Varisli, L. ; Veal, E.A. ; Yalçın, A.S. ; Yelisyeyeva, O. ; Žarković, N. ; Zatloukalová, M. ; Zielonka, J. ; Touyz, R.M. ; Papapetropoulos, A. ; Grune, T. ; Lamas, S. ; Schmidt, H.H.H.W. ; Di Lisa, F. ; Daiber, A.
European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS).Giesert, F. ; Glasl, L. ; Zimprich, A. ; Ernst, L. ; Piccoli, G. ; Stautner, C. ; Zerle, J. ; Hölter, S.M. ; Vogt Weisenhorn, D.M. ; Wurst, W.
The pathogenic LRRK2 R1441C mutation induces specific deficits modeling the prodromal phase of Parkinson's disease in the mouse.Mazaheri, F. ; Snaidero, N. ; Kleinberger, G. ; Madore, C. ; Daria, A. ; Werner, G. ; Krasemann, S. ; Capell, A. ; Trümbach, D. ; Wurst, W. ; Brunner, B. ; Bultmann, S. ; Tahirovic, S. ; Kerschensteiner, M. ; Misgeld, T. ; Butovsky, O. ; Haass, C.
TREM2 deficiency impairs chemotaxis and microglial responses to neuronal injury.Yumlu, S. ; Stumm, J. ; Bashir, S. ; Dreyer, A.K. ; Lisowski, P. ; Danner, E. ; Kühn, R.
Gene editing and clonal isolation of human induced pluripotent stem cells using CRISPR/Cas9.Maiorino, M. ; Conrad, M. ; Ursini, F.
GPx4, lipid peroxidation, and cell death: Discoveries, rediscoveries, and open issues.Zilka, O. ; Shah, R. ; Li, B. ; Friedmann Angeli, J.P.F. ; Griesser, M. ; Conrad, M. ; Pratt, D.A.
On the mechanism of cytoprotection by ferrostatin-1 and liproxstatin-1 and the role of lipid peroxidation in ferroptotic cell death.Kleinberger, G. ; Brendel, M.D. ; Mracsko, E. ; Wefers, B. ; Groeneweg, L. ; Xiang, X. ; Focke, C. ; Deußing, M. ; Suárez-Calvet, M. ; Mazaheri, F. ; Parhizkar, S. ; Pettkus, N. ; Wurst, W. ; Feederle, R. ; Bartenstein, P. ; Mueggler, T. ; Arzberger, T. ; Knuesel, I. ; Rominger, A. ; Haass, C.
The FTD-like syndrome causing TREM2 T66M mutation impairs microglia function, brain perfusion, and glucose metabolism.Friedmann Angeli, J.P.F. ; Shah, R. ; Pratt, D.A. ; Conrad, M.
Ferroptosis inhibition: Mechanisms and opportunities.Schriever, S.C. ; Zimprich, A. ; Pfuhlmann, K. ; Baumann, P. ; Giesert, F. ; Klaus, V. ; Kabra, D. ; Hafen, U. ; Romanov, A. ; Tschöp, M.H. ; Wurst, W. ; Conrad, M. ; Hölter, S.M. ; Weisenhorn, D.M. ; Pfluger, P.T.
Alterations in neuronal control of body weight and anxiety behavior by glutathione peroxidase 4 deficiency.Doll, S. ; Conrad, M.
Iron and ferroptosis: A still ill-defined liaison.Schludi, M.H. ; Becker, L. ; Garrett, L. ; Gendron, T.F. ; Zhou, Q. ; Schreiber, F. ; Popper, B. ; Dimou, L. ; Strom, T.M. ; Winkelmann, J. ; von Thaden, A. ; Rentzsch, K. ; May, S. ; Michaelsen, M. ; Schwenk, B.M. ; Tan, J. ; Schoser, B. ; Dieterich, M. ; Petrucelli, L. ; Hölter, S.M. ; Wurst, W. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Klopstock, T. ; Arzberger, T. ; Edbauer, D.
Spinal poly-GA inclusions in a C9orf72 mouse model trigger motor deficits and inflammation without neuron loss.Zimprich, A. ; Östereicher, M.A. ; Becker, L. ; Dirscherl, P. ; Ernst, L. ; Fuchs, H. ; Gailus-Durner, V. ; Garrett, L. ; Giesert, F. ; Glasl, L. ; Hummel, A.M. ; Rozman, J. ; Hrabě de Angelis, M. ; Vogt-Weisenhorn, D. ; Wurst, W. ; Hölter, S.M.
Analysis of locomotor behavior in the German Mouse Clinic.Ryan, D.P. ; Henzel, K.S. ; Pearson, B.L. ; Siwek, M.E. ; Papazoglou, A. ; Guo, L. ; Paesler, K. ; Yu, M. ; Müller, R. ; Xie, K. ; Schröder, S. ; Becker, L. ; Garrett, L. ; Hölter, S.M. ; Neff, F. ; Rácz, I. ; Rathkolb, B. ; Rozman, J. ; Ehninger, G. ; Klingenspor, M. ; Klopstock, T. ; Wolf, E. ; Wurst, W. ; Zimmer, A.D. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Sidiropoulou, K. ; Weiergräber, M. ; Zhou, Y. ; Ehninger, D.
A paternal methyl donor-rich diet altered cognitive and neural functions in offspring mice.Vartholomaiou, E. ; Madon-Simon, M. ; Hagmann, S. ; Mühlebach, G. ; Wurst, W. ; Floß, T. ; Picard, D.
Cytosolic Hsp90a and its mitochondrial isoform Trap1 are differentially required in a breast cancer model.Rodriguez Camargo, D.C. ; Tripsianes, K. ; Buday, K. ; Frankó, A. ; Göbl, C. ; Hartlmüller, C. ; Sarkar, R. ; Aichler, M. ; Mettenleiter, G. ; Schulz, M. ; Böddrich, A. ; Erck, C. ; Martens, H. ; Walch, A.K. ; Madl, T. ; Wanker, E.E. ; Conrad, M. ; Hrabě de Angelis, M. ; Reif, B.
The redox environment triggers conformational changes and aggregation of hIAPP in Type II Diabetes.Beckervordersandforth, R. ; Ebert, B. ; Schäffner, I. ; Moss, J. ; Fiebig, C. ; Shin, J. ; Moore, D.L. ; Ghosh, L. ; Trinchero, M.F. ; Stockburger, C. ; Friedland, K. ; Steib, K. ; von Wittgenstein, J. ; Keiner, S. ; Redecker, C. ; Hölter, S.M. ; Xiang, W. ; Wurst, W. ; Jagasia, R. ; Schinder, A.F. ; Ming, G.l. ; Toni, N. ; Jessberger, S. ; Song, H. ; Lie, D.C.C.
Role of mitochondrial metabolism in the control of early lineage progression and aging phenotypes in adult hippocampal neurogenesis.Szibor, M. ; Dhandapani, P.K. ; Dufour, E. ; Holmström, K.M. ; Zhuang, Y. ; Salwig, I. ; Wittig, I. ; Heidler, J. ; Gizatullina, Z. ; Gainutdinov, T. ; German Mouse Clinic Consortium (Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Aguilar-Pimentel, J.A. ; Schmidt-Weber, C.B. ; Becker, L. ; Adler, T. ; Treise, I. ; Horsch, M. ; Beckers, J. ; Moreth, K. ; Garrett, L. ; Hölter, S.M. ; Zimprich, A. ; Wurst, W. ; Hans, W. ; Amarie, O.V. ; Graw, J. ; Rozman, J. ; Calzada-Wack, J. ; Da Silva-Buttkus, P. ; Neff, F. ; Rácz, I. ; Rathkolb, B. ; Östereicher, M.A. ; Steinkamp, R. ; Lengger, C. ; Maier, H. ; Stoeger, C. ; Leuchtenberger, S.) ; Nandania, J. ; Velagapudi,V. ; Wietelmann, A. ; Rustin, P. ; Gellerich, F.N. ; Jacobs, H.T. ; Braun, T.
Broad AOX expression in a genetically tractable mouse model does not disturb normal physiology.Kagan, V.E. ; Mao, G. ; Qu, F. ; Friedmann Angeli, J.P.F. ; Doll, S. ; St. Croix, C. ; Dar, H.H. ; Liu, B. ; Tyurin, V.A. ; Ritov, V.B. ; Kapralov, A.A. ; Amoscato, A.A. ; Jiang, J. ; Anthonymuthu, T. ; Mohammadyani, D. ; Yang, Q. ; Proneth, B. ; Klein-Seetharaman, J. ; Watkins, S. ; Bahar, I. ; Greenberger, J. ; Mallampalli, R.K. ; Stockwell, B.R. ; Tyurina, Y.Y. ; Conrad, M. ; Bayir, H.
Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis.Graveline, R. ; Marcinkiewicz, K. ; Choi, S. ; Paquet, M. ; Wurst, W. ; Floß, T. ; David, G.
The chromatin associated Phf12 protein maintains nucleolar integrity and prevents premature cellular senescence.Deng, T. ; Postnikov, Y. ; Zhang, S. ; Garrett, L. ; Becker, L. ; Rácz, I. ; Hölter, S.M. ; Wurst, W. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Bustin, M.
Interplay between H1 and HMGN epigenetically regulates OLIG1&2 expression and oligodendrocyte differentiation.Metzger, M.W. ; Walser, S.M. ; Aprile-Garcia, F. ; Dedic, N. ; Chen, A. ; Holsboer, F. ; Arzt, E. ; Wurst, W. ; Deussing, J.M.
Genetically dissecting P2rx7 expression within the central nervous system using conditional humanized mice.Reitmeir, P. ; Linkohr, B. ; Heier, M. ; Molnos, S. ; Strobl, R. ; Schulz, H. ; Breier, M. ; Faus-Kessler, T. ; Küster, D.M. ; Wulff, A. ; Grallert, H. ; Grill, E. ; Peters, A. ; Graw, J.
Common eye diseases in older adults of Southern Germany: Results from the KORA-Age Study.Doll, S. ; Proneth, B. ; Tyurina, A.A. ; Panzilius, E. ; Kobayashi, S. ; Ingold, I. ; Irmler, M. ; Beckers, J. ; Aichler, M. ; Walch, A.K. ; Prokisch, H. ; Trümbach, D. ; Mao, G. ; Qu, F. ; Bayir, H. ; Füllekrug, J. ; Scheel, C. ; Wurst, W. ; Schick, J. ; Kagan, V.E. ; Friedmann Angeli, J.P.F. ; Conrad, M.
ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition.Huettl, R.E. ; Huber, A.B.
Characterizing semaphorin-mediated effects on sensory and motor axon pathfinding and connectivity during embryonic development.Kuruthukulangarakoola, G.T. ; Zhang, J. ; Albert, A. ; Winkler, J.B. ; Lang, H. ; Buegger, F. ; Gaupels, F. ; Heller, W. ; Michalke, B. ; Sarioglu, H. ; Schnitzler, J.-P. ; Hebelstrup, K.H. ; Durner, J. ; Lindermayr, C.
Nitric oxide-fixation by non-symbiotic hemoglobin proteins in Arabidopsis thaliana under N-limited conditions.Conrad, M. ; Schweizer, U.
Mouse models that target individual selenoproteins.Friedmann Angeli, J.P.F. ; Proneth, B. ; Conrad, M.
Glutathione peroxidase 4 and ferroptosis.Wefers, B. ; Brandl, C. ; Ortiz, O. ; Wurst, W. ; Kühn, R.
Genome editing in mice using TALE nucleases.Zimprich, A. ; Mroz, G. ; Meyer Zu Reckendorf, C. ; Anastasiadou, S. ; Förstner, P. ; Garrett, L. ; Hölter, S.M. ; Becker, L. ; Rozman, J. ; Prehn, C. ; Rathkolb, B. ; Moreth, K. ; Wurst, W. ; Klopstock, T. ; Klingenspor, M. ; Adamski, J. ; Wolf, E. ; Bekeredjian, R. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Knöll, B.
Serum response factor (SRF) ablation interferes with acute stress-associated immediate and long-term coping mechanisms.Brandl, C. ; Breinlich, V. ; Stark, K.J. ; Enzinger, S. ; Aßenmacher, M. ; Olden, M. ; Grassmann, F. ; Graw, J. ; Heier, M. ; Peters, A. ; Helbig, H. ; Küchenhoff, H. ; Weber, B.H.F. ; Heid, I.M.
Features of age-related macular degeneration in the general adults and their dependency on age, sex, and smoking: Results from the German KORA study.Ainsbury, E.A. ; Barnard, S. ; Bright, S. ; Dalke, C. ; Jarrin, M. ; Kunze, S. ; Tanner, R. ; Dynlacht, J.R. ; Quinlan, R.A. ; Graw, J. ; Kadhim, M. ; Hamada, N.
Ionizing radiation induced cataracts: Recent biological and mechanistic developments and perspectives for future research.Regina, B.F. ; Gladyshev, V.N. ; Arner, E.S.J. ; Berry, M.J. ; Bruford, E.A. ; Burk, R.F. ; Carlson, B.A. ; Castellano, S. ; Chavatte, L. ; Conrad, M. ; Copeland, P.R. ; Diamond, A.M. ; Driscoll, D.M. ; Ferreiro, A. ; Flohé, L. ; Green, F.R. ; Guigo, R. ; Handy, D.E. ; Hatfield, D.L. ; Hesketh, J. ; Hoffmann, P.R. ; Holmgren, A. ; Hondal, R.J. ; Howard, M.T. ; Huang, K.M. ; Kim, H.Y. ; Kim, I.Y. ; Köhrle, J. ; Krol, A. ; Kryukov, G.V. ; Lee, B.J. ; Lee, B.C. ; Lei, X.G. ; Liu, Q. ; Lescure, A. ; Lobanov, A.V. ; Loscalzo, J. ; Maiorino, M. ; Mariotti, M. ; Prabhu, K.S. ; Rayman, M.P. ; Rozovsky, S. ; Salinas, G. ; Schmidt, E.E. ; Schomburg, L. ; Schweizer, U. ; Simonović, M. ; Sunde, R.A. ; Tsuji, P.A. ; Tweedie, S. ; Ursini, F.F. ; Whanger, P.D. ; Zhang, Y.
Selenoprotein gene nomenclature.Fuchs, H. ; Sabrautzki, S. ; Przemeck, G.K.H. ; Leuchtenberger, S. ; Lorenz-Depiereux, B. ; Becker, L. ; Rathkolb, B. ; Horsch, M. ; Garrett, L. ; Östereicher, M.A. ; Hans, W. ; Abe, K. ; Sagawa, N. ; Rozman, J. ; Vargas Panesso, I.L. ; Sandholzer, M. ; Lisse, T.S. ; Adler, T. ; Aguilar-Pimentel, J.A. ; Calzada-Wack, J. ; Ehrhard, N. ; Elvert, R. ; Gau, C. ; Hölter, S.M. ; Micklich, K. ; Moreth, K. ; Prehn, C. ; Puk, O. ; Rácz, I. ; Stoeger, C. ; Vernaleken, A. ; Michel, D. ; Diener, S. ; Wieland, T. ; Adamski, J. ; Bekeredjian, R. ; Lengger, C. ; Maier, H. ; Neff, F. ; Ollert, M. ; Stöger, T. ; Yildirim, A.Ö. ; Strom, T.M. ; Zimmer, A. ; Wolf, E. ; Wurst, W. ; Klopstock, T. ; Beckers, J. ; Gailus-Durner, V. ; Hrabě de Angelis, M.
The first Scube3 mutant mouse line with pleiotropic phenotypic alterations.Hörster, H. ; Garthe, A. ; Walker, T.L. ; Ichwan, M. ; Steiner, B. ; Khan, M.A. ; Lie, D.C.C. ; Nicola, Z. ; Ramirez-Rodriguez, G. ; Kempermann, G.
p27kip1 is required for functionally relevant adult hippocampal neurogenesis in mice.Wittmann, A. ; Grimm, M. ; Scherthan, H. ; Horsch, M. ; Beckers, J. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Ford, S.J. ; Burton, N.C. ; Razansky, D. ; Trümbach, D. ; Aichler, M. ; Walch, A.K. ; Calzada-Wack, J. ; Neff, F. ; Wurst, W. ; Hartmann, T. ; Floß, T.
Sphingomyelin synthase 1 is essential for male fertility in mice.Weber, T. ; Namikawa, K. ; Winter, B. ; Müller-Brown, K. ; Kühn, R. ; Wurst, W. ; Köster, R.W.
Caspase-mediated apoptosis induction in zebrafish cerebellar Purkinje neurons.Kim, S.E. ; Zhang, L. ; Ma, K. ; Riegman, M. ; Chen, F. ; Ingold, I. ; Conrad, M. ; Turker, M.Z. ; Gao, M. ; Jiang, X. ; Monette, S. ; Pauliah, M. ; Gonen, M. ; Zanzonico, P. ; Quinn, T. ; Wiesner, U. ; Bradbury, M.S. ; Overholtzer, M.
Ultrasmall nanoparticles induce ferroptosis in nutrient-deprived cancer cells and suppress tumour growth.de Angelis, M. ; Giesert, F. ; Finan, B. ; Clemmensen, C. ; Müller, T.D. ; Vogt Weisenhorn, D.M. ; Tschöp, M.H. ; Schramm, K.-W.
Determination of thyroid hormones in mouse tissues by isotope-dilution microflow liquid chromatography-mass spectrometry method.Brandl, C.
Genome engineering in mice using TALEN or CRISPR/Cas9 nucleases.Sabrautzki, S. ; Sandholzer, M.A. ; Lorenz-Depiereux, B. ; Brommage, R. ; Przemeck, G.K.H. ; Vargas Panesso, I.L. ; Vernaleken, A. ; Garrett, L. ; Baron, K. ; Yildirim, A.Ö. ; Rozman, J. ; Rathkolb, B. ; Gau, C. ; Hans, W. ; Hölter, S.M. ; Marschall, S. ; Stoeger, C. ; Becker, L. ; Fuchs, H. ; Gailus-Durner, V. ; Klingenspor, M. ; Klopstock, T. ; Lengger, C. ; Stefanie, L. ; Wolf, E. ; Strom, T.M. ; Wurst, W. ; Hrabě de Angelis, M.
Viable EdnraY129F mice feature human mandibulofacial dysostosis with alopecia (MFDA) syndrome due to the homologue mutation.Dickinson, M.E. ; Flenniken, A.M. ; Ji, X. ; Teboul, L. ; Wong, M.D. ; White, J.K. ; Meehan, T.F. ; Weninger, W.J. ; Westerberg, H. ; Adissu, H.A. ; Baker, C.N. ; Bower, L. ; Brown, J.M. ; Caddle, L.B. ; Chiani, F. ; Clary, D. ; Cleak, J. ; Daly, M.J. ; Denegre, J.M. ; Doe, B. ; Dolan, M.E. ; Edie, S.M. ; Fuchs, H. ; Gailus-Durner, V. ; Galli, A. ; Gambadoro, A. ; Gallegos, J. ; Guo, S. ; Horner, N.R. ; Hsu, C.W. ; Johnson, S.J. ; Kalaga, S. ; Keith, L.C. ; Lanoue, L. ; Lawson, T.N. ; Lek, M. ; Mark, M. ; Marschall, S. ; Mason, J. ; McElwee, M.L. ; Newbigging, S. ; Nutter, L.M. ; Peterson, K.A. ; Ramirez-Solis, R. ; Rowland, D.J. ; Ryder, E. ; Samocha, K.E. ; Seavitt, J.R. ; Selloum, M. ; Szoke-Kovacs, Z. ; Tamura, M. ; Trainor, A.G. ; Tudose, I. ; Wakana, S. ; Warren, J. ; Wendling, O. ; West, D.B. ; Wong, L.J. ; Yoshiki, A. ; MacArthur, D.G. ; Tocchini-Valentini, G.P. ; Gao, X. ; Flicek, P. ; Bradley, A. ; Skarnes, W.C. ; Justice, M.J. ; Parkinson, H.E. ; Moore, M. ; Wells, S. ; Braun, R.E. ; Svenson, K.L. ; Hrabě de Angelis, M. ; Herault, Y. ; Mohun, T. ; Mallon, A.M. ; Henkelman, R.M. ; Brown, S.D. ; Adams, D.J. ; Lloyd, K.C.K. ; McKerlie, C. ; Beaudet, A.L. ; Bucan, M. ; Murray, S.A.
High-throughput discovery of novel developmental phenotypes.Adam, J. ; Brandmaier, S. ; Leonhardt, J. ; Scheerer, M.F. ; Mohney, R.P. ; Xu, T. ; Bi, J. ; Rotter, M. ; Troll, M. ; Chi, S. ; Heier, M. ; Herder, C. ; Rathmann, W.G. ; Giani, G. ; Adamski, J. ; Illig, T. ; Strauch, K. ; Li, Y. ; Gieger, C. ; Peters, A. ; Suhre, K. ; Ankerst, D.P. ; Meitinger, T. ; Hrabě de Angelis, M. ; Roden, M. ; Neschen, S. ; Kastenmüller, G. ; Wang-Sattler, R.
Metformin effect on non-targeted metabolite profiles in patients with type 2 diabetes and multiple murine tissues.Telley, L. ; Cadilhac, C. ; Cioni, J.M. ; Saywell, V. ; Jahannault-Talignani, C. ; Huettl, R.E. ; Sarrailh-Faivre, C. ; Dayer, A. ; Huber, A.B. ; Ango, F.
Dual function of NRP1 in axon guidance and subcellular target recognition in cerebellum.Schick, J. ; Seisenberger, C. ; Beig, J. ; Bürger, A. ; Iyer, V. ; Maier, V. ; Perera, S. ; Rosen, B. ; Skarnes, W.C. ; Wurst, W.
CRISPR-Cas9 enables conditional mutagenesis of challenging loci.Saller, M. ; Hüttl, R.E. ; Hanuschick, P. ; Amend, A.-L. ; Alberton, P. ; Aszodi, A. ; Huber, A.B.
The role of Sema3-Npn-1 signaling during diaphragm innervation and muscle development.Kirsch, J. ; Schneider, H. ; Pagel, J.I. ; Rehberg, M. ; Singer, M. ; Hellfritsch, J. ; Chillo, O. ; Schubert, K.M. ; Qiu, J. ; Pogoda, K. ; Kameritsch, P. ; Uhl, B. ; Pircher, J. ; Deindl, E. ; Müller, S. ; Kirchner, T. ; Pohl, U. ; Conrad, M. ; Beck, H.
Endothelial dysfunction, and a prothrombotic, proinflammatory phenotype is caused by loss of mitochondrial thioredoxin reductase in endothelium.Hoppe, P.S. ; Schwarzfischer, M. ; Loeffler, D. ; Kokkaliaris, K.D. ; Hilsenbeck, O. ; Moritz, N. ; Endele, M. ; Filipczyk, A. ; Gambardella, A. ; Ahmed, N. ; Etzrodt, M. ; Coutu, D.L. ; Rieger, M.A. ; Marr, C. ; Strasser, M. ; Schauberger, B. ; Burtscher, I. ; Ermakova, O. ; Bürger, A. ; Lickert, H. ; Nerlov, C. ; Theis, F.J. ; Schroeder, T.
Early myeloid lineage choice is not initiated by random PU.1 to GATA1 protein ratios.Kokkaliaris, K.D. ; Drew, E. ; Endele, M. ; Loeffler, D. ; Hoppe, P.S. ; Hilsenbeck, O. ; Schauberger, B. ; Hinzen, C. ; Skylaki, S. ; Theodorou, M. ; Kieslinger, M. ; Lemischka, I. ; Moore, K. ; Schroeder, T.
Identification of factors promoting ex vivo maintenance of mouse hematopoietic stem cells by long-term single-cell quantification.Peng, X. ; Giménez-Cassina, A. ; Petrus, P. ; Conrad, M. ; Rydén, M. ; Arner, E.S.J.
Thioredoxin reductase 1 suppresses adipocyte differentiation and insulin responsiveness.Dean-Ben, X.L. ; Stiel, A.-C. ; Jiang, Y. ; Ntziachristos, V. ; Westmeyer, G.G. ; Razansky, D.
Imaging the distribution of photoswitchable probes with temporally-unmixed multispectral optoacoustic tomography.Vogt Weisenhorn, D.M. ; Giesert, F. ; Wurst, W.
Diversity matters - heterogeneity of dopaminergic neurons in the ventral mesencephalon and its relation to Parkinson's disease.Eden, M. ; Meder, B. ; Völkers, M. ; Poomvanicha, M. ; Domes, K. ; Branchereau, M. ; Marck, P. ; Will, R. ; Bernt, A. ; Rangrez, A. ; Busch, M. ; German Mouse Clinic Consortium (Adler, T. ; Aguilar-Pimentel, J.A. ; Becker, L. ; Beckers, J. ; Busch, D.H. ; Calzada-Wack, J. ; Fuchs, H. ; Gailus-Durner, V. ; Garrett, L. ; Graw, J. ; Götz, A. ; Hans, W. ; Hölter, S.M. ; Horsch, M. ; Klein-Rodewald, T. ; Lengger, C. ; Leuchtenberger, S. ; Maier, H. ; Neff, F. ; Ollert, M. ; Prehn, C. ; Puk, O. ; Rácz, I. ; Rathkolb, B. ; Rozman, J. ; Schrewe, A. ; Schulz, H. ; Stoeger, C. ; Tost, M. ; Wurst, W.) ; Hrabě de Angelis, M. ; Heymes, C. ; Rottbauer, W. ; Most, P. ; Hofmann, F. ; Frey, N.
Erratum: Myoscape controls cardiac calcium cycling and contractility via regulation of L-type calcium channel surface expression.Carlson, B.A. ; Tobe, R. ; Yefremova, E. ; Tsuji, P.A. ; Hoffmann, V.J. ; Schweizer, U. ; Gladyshev, V.N. ; Hatfield, D.L. ; Conrad, M.
Glutathione peroxidase 4 and vitamin E cooperatively prevent hepatocellular degeneration.Kuperman, Y. ; Weiss, M. ; Dine, J. ; Staikin, K. ; Golani, O. ; Ramot, A. ; Nahum, T. ; Kühne, C. ; Shemesh, Y. ; Wurst, W. ; Harmelin, A. ; Deussing, J.M. ; Eder, M. ; Chen, A.
CRFR1 in AgRP neurons modulates sympathetic nervous system activity to adapt to cold stress and fasting.Hüttl, R.E. ; Huber, A.B.
Pax6: Funktionen entlang der rostro-kaudalen Achse des Neuralrohrs.Reichel, J.M. ; Bedenk, B.T. ; Gassen, N. ; Hafner, K. ; Bura, S.A. ; Almeida-Correa, S. ; Genewsky, A. ; Dedic, N. ; Giesert, F. ; Agarwal, A. ; Nave, K.A. ; Rein, T. ; Czisch, M. ; Deussing, J.M. ; Wotjak, C.T.
Beware of your Cre-Ation: lacZ expression impairs neuronal integrity and hippocampus-dependent memory.Welk, V. ; Coux, O. ; Kleene, V. ; Abeza, C. ; Trümbach, D. ; Eickelberg, O. ; Meiners, S.
Inhibition of proteasome activity induces formation of alternative proteasome complexes.Eden, M. ; Meder, B. ; Völkers, M. ; Poomvanicha, M. ; Domes, K. ; Branchereau, M. ; Marck, P. ; Will, R. ; Bernt, A. ; Rangrez, A. ; Busch, M. ; German Mouse Clinic Consortium (Adler, T. ; Aguilar-Pimentel, J.A. ; Becker, L. ; Beckers, J. ; Busch, D.H. ; Calzada-Wack, J. ; Fuchs, H. ; Gailus-Durner, V. ; Garrett, L. ; Graw, J. ; Götz, A. ; Hans, W. ; Hölter, S.M. ; Horsch, M. ; Klein-Rodewald, T. ; Lengger, C. ; Leuchtenberger, S. ; Maier, H. ; Neff, F. ; Ollert, M. ; Prehn, C. ; Puk, O. ; Rácz, I. ; Rathkolb, B. ; Rozman, J. ; Schrewe, A. ; Schulz, H. ; Stoeger, C. ; Tost, M. ; Wurst, W. ; Frey, N.) ; Hrabě de Angelis, M. ; Heymes, C. ; Rottbauer, W. ; Most, P. ; Hofmann, F.
Myoscape controls cardiac calcium cycling and contractility via regulation of L-type calcium channel surface expression.Götz, S. ; Rauser, B. ; Brodski, C. ; Prakash, N.
Early and localized expression of ion channels and ion channel subunits in the developing mesodiencephalic dopaminergic domain of the mouse embryo.Kumar, S. ; Rathkolb, B. ; Kemter, E. ; Sabrautzki, S. ; Michel, D. ; Adler, T. ; Becker, L. ; Beckers, J. ; Busch, D.H. ; Garrett, L. ; Hans, W. ; Hölter, S.M. ; Horsch, M. ; Klingenspor, M. ; Klopstock, T. ; Rácz, I. ; Rozman, J. ; Vargas Panesso, I.L. ; Vernaleken, A. ; Zimmer, A. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Wolf, E. ; Aigner, B.
Generation and standardized, systemic phenotypic analysis of Pou3f3L423P mutant mice.Massner, C. ; Pariani, G. ; Rolbieski, H. ; Sigmund, F. ; Westmeyer, G.G.
Genetically controlled uptake of ferritin as an MRI contrast agent.Kistler, M. ; Muntean, A. ; Szymczak, W. ; Rink, N. ; Fuchs, H. ; Gailus-Durner, V. ; Wurst, W. ; Hoeschen, C. ; Klingenspor, M. ; Hrabě de Angelis, M. ; Rozman, J.
Diet-induced and mono-genetic obesity alter volatile organic compound signature in mice.Meiser, J. ; Delcambre, S. ; Wegner, A. ; Jager, C. ; Ghelfi, J. ; D'Herouel, A.F. ; Dong, X. ; Weindl, D. ; Stautner, C. ; Nonnenmacher, Y. ; Michelucci, A. ; Popp, O. ; Giesert, F. ; Schildknecht, S. ; Krämer, L. ; Schneider, J.G. ; Woitalla, D. ; Wurst, W. ; Skupin, A. ; Weisenhorn, D.M. ; Kruger, R. ; Leist, M. ; Hiller, K.
Loss of DJ-1 impairs antioxidant response by altered glutamine and serine metabolism.Conrad, M. ; Friedmann Angeli, J.P.F. ; Vandenabeele, P. ; Stockwell, B.R.
Regulated necrosis: Disease relevance and therapeutic opportunities.Telorack, M. ; Meyer, M. ; Ingold, I. ; Conrad, M. ; Bloch, W. ; Werner, S.
A glutathione-Nrf2-thioredoxin cross-talk ensures keratinocyte survival and efficient wound repair.Klafke, R. ; Prem Anand, A.A. ; Wurst, W. ; Prakash, N. ; Wizenmann, A.
Differences in the spatiotemporal expression and epistatic gene regulation of the mesodiencephalic dopaminergic precursor marker PITX3 during chicken and mouse development.Nechiporuk, T. ; McGann, J. ; Mullendorff, K. ; Hsieh, J. ; Wurst, W. ; Floß, T. ; Mandel, G.
The REST remodeling complex protects genomic integrity during embryonic neurogenesis.Gascón, S. ; Murenu, E. ; Masserdotti, G. ; Ortega, F. ; Russo, G.L. ; Petrik, D. ; Deshpande, A. ; Heinrich, C. ; Karow, M. ; Robertson, S.P. ; Schroeder, T. ; Beckers, J. ; Irmler, M. ; Berndt, C. ; Friedmann Angeli, J.P.F. ; Conrad, M. ; Berninger, B. ; Götz, M.
Identification and successful negotiation of a metabolic checkpoint in direct neuronal repogramming.Holzerova, E. ; Danhauser, K. ; Haack, T.B. ; Kremer, L.S. ; Melcher, M. ; Ingold, I. ; Kobayashi, S. ; Terrile, C. ; Wolf, P. ; Schaper, J. ; Mayatepek, E. ; Baertling, F. ; Friedmann Angeli, J.P.F. ; Conrad, M. ; Strom, T.M. ; Meitinger, T. ; Prokisch, H. ; Distelmaier, F.
Human thioredoxin 2 deficiency impairs mitochondrial redox homeostasis and causes early-onset neurodegeneration.Hüttl, R.E. ; Eckstein, S. ; Stahl, T. ; Petricca, S. ; Ninkovic, J. ; Götz, M. ; Huber, A.B.
Functional dissection of the Pax6 paired domain: Roles in neural tube patterning and peripheral nervous system development.Bosch, Michaela
Generation and analysis of FUS and TMEM106B mouse models.Dedic, N.
Genetic dissection of CRH-controlled neurocircuitries of stress.Theodorou, M.
Translational Strategies to address Parkinson's disease.Mu, L.
Examining the role of SoxC transcription factors in adult hippocampal neuronal differentiation.Kolarz, A.
Genetically dissecting the role of CRHR2 and UCN2 in the control of emotional behavior.Garrett, L. ; Zhang, J. ; Niedermeier, K.M. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Vogt Weisenhorn, D.M. ; Wurst, W. ; Hölter, S.M.
Conditional reduction of adult born doublecortin-positive neurons reversibly impairs selective behaviors.Hölter, S.M. ; Einicke, J. ; Sperling, B. ; Zimprich, A. ; Garrett, L. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Wurst, W.
Tests for anxiety-related behavior in mice.Hölter, S.M. ; Garrett, L. ; Einicke, J. ; Sperling, B. ; Dirscherl, P. ; Zimprich, A. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Wurst, W.
Assessing cognition in mice.Garrett, L. ; Zhang, J. ; Zimprich, A. ; Niedermeier, K.M. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Vogt Weisenhorn, D.M. ; Wurst, W. ; Hölter, S.M.
Conditional reduction of adult born doublecortin-positive neurons reversibly impairs selective behaviors.Söllner, R.W.
Establishment and cell biological analysis of neurodegeneration models in zebrafish based on Parkinson’s disease-linked genes LRRK2 and PINK1.Seibt, T.
Relevanz posttranslationaler Modifikation der Glutathionperoxidase 4 (Gpx4) in der Signaltransduktion sowie Identifizierung genetischer Polymorphismen der humanen GPX4 zur präferenziellen Ausbildung einer Delayed Graft Function (DGF).Zerle, J.
Analysis of LRRK2 function in Parkinsons's disease etiology with focus on mitochondrial dysfunction.Dean-Ben, X.L. ; Stiel, A.C. ; Jiang, Y. ; Ntziachristos, V. ; Westmeyer, G.G. ; Razansky, D.
Light fluence normalization in turbid tissues via temporally unmixed multispectral optoacoustic tomography.Kneipp, M. ; Estrada, H. ; Lauri, A. ; Turner, J.E. ; Ntziachristos, V. ; Westmeyer, G.G. ; Razansky, D.
Volumetric tracking of migratory melanophores during zebrafish development by optoacoustic microscopy.Fukusumi, Y. ; Meier, F. ; Götz, S. ; Matheus, F. ; Irmler, M. ; Beckervordersandforth, R. ; Faus-Kessler, T. ; Minina, E. ; Rauser, B. ; Zhang, J. ; Arenas, E. ; Andersson, E.A. ; Niehrs, C. ; Beckers, J. ; Simeone, A. ; Wurst, W. ; Prakash, N.
Dickkopf3 promotes the differentiation of a rostrolateral midbrain dopaminergic neuronal subset in vivo and from pluripotent stem cells in vitro in the mouse.Cernilogar, F.M. ; di Giaimo, R. ; Rehfeld, F. ; Cappello, S. ; Lie, D.C.
RNA interference machinery-mediated gene regulation in mouse adult neural stem cells.Grünler, N.
Untersuchungen zur Rolle der Glutathion-Peroxidase 4 als möglicher Redox-Sensor in Säugetierzellen.Helmbrecht, M.S.
Axonal wiring defects and critical period plasticity in the postnatal motor system.Kumar, D. ; Dedic, N. ; Flachskamm, C. ; Voulé, S. ; Deussing, J.M. ; Kimura, M.
CACNA1C (Cav1.2) modulates electroencephalographic rhythm and rapid eye movement sleep recovery.Sim, N. ; Gottschalk, S. ; Pal, R. ; Delbianco, M. ; Degtyaruk, O. ; Razansky, D. ; Westmeyer, G.G. ; Ntziachristos, V. ; Parker, D. ; Mishra, A.
Wavelength-dependent optoacoustic imaging probes for NMDA receptor visualisation.Rosen, B. ; Schick, J. ; Wurst, W.
Beyond knockouts: The International Knockout Mouse Consortium delivers modular and evolving tools for investigating mammalian genes.Cruz Perez, C. ; Lauri, A. ; Symvoulidis, P. ; Cappetta, M. ; Erdmann, A. ; Westmeyer, G.G.
Calcium neuroimaging in behaving zebrafish larvae using a turn-key light field camera.Bender, J. ; Engeholm, M. ; Ederer, M.S. ; Breu, J. ; Møller, T.C. ; Michalakis, S. ; Rasko, T. ; Wanker, E.E. ; Biel, M. ; Martinez, K.L. ; Wurst, W. ; Deussing, J.M.
Corticotropin-Releasing Hormone Receptor Type 1 (CRHR1) clustering with MAGUKs is mediated via its C-terminal PDZ binding motif.Martinez-Ferre, A. ; Lloret-Quesada, C. ; Prakash, N. ; Wurst, W. ; Rubenstein, J.L. ; Martinez, S.
Fgf15 regulates thalamic development by controlling the expression of proneural genes.Bender, J. ; Ederer, M.S. ; Breu, J. ; Engeholm, M. ; Michalakis, S. ; Wurst, W. ; Deussing, J.M.
Clustering of corticotropin-releasing hormone receptor type 1 with membrane-associated guanylate kinases.Marcos, S. ; González-Lázaro, M. ; Beccari, L. ; Carramolino, L. ; Martin-Bermejo, M.J. ; Amarie, O.V. ; Martín, D.M. ; Torroja, C. ; Bogdanović, O. ; Doohan, R. ; Puk, O. ; Hrabě de Angelis, M. ; Graw, J. ; Gómez-Skarmeta, J.L. ; Casares, F. ; Torres, M. ; Bovolenta, P.
Meis1 coordinates a network of genes implicated in eye development and microphthalmia.Lagouge, M. ; Mourier, A. ; Lee, H.J. ; Spåhr, H. ; Wai, T. ; Kukat, C. ; Silva Ramos, E. ; Motori, E. ; Busch, J.D. ; Siira, S. ; German Mouse Clinic Consortium (Larsson, N.G. ; Aguilar-Pimentel, J.A. ; Amarie, O.V. ; Becker, L. ; Beckers, J. ; Brachthäuser, L. ; Calzada-Wack, J. ; Eickelberg, O. ; Gailus-Durner, V. ; Garrett, L. ; Graw, J. ; Hans, W. ; Hölter, S.M. ; Horsch, M. ; Hrabě de Angelis, M. ; Janik, D. ; Klein-Rodewald, T. ; Lengger, C. ; Leuchtenberger, S. ; Maier, H. ; Moreth, K. ; Neff, F. ; Östereicher, M.A. ; Puk, O. ; Rácz, I. ; Rathkolb, B. ; Rozman, J. ; Steinkamp, R. ; Stoeger, C. ; Stöger, T. ; Vernaleken, A. ; Wurst, W. ; Yildirim, A.Ö. ; Zimprich, A.) ; Kremmer, E. ; Filipovska, A.
SLIRP regulates the rate of mitochondrial protein synthesis and protects LRPPRC from degradation.Hrabě de Angelis, M. ; Nicholson, G. ; Selloum, M. ; White, J.K. ; Morgan, H. ; Ramirez-Solis, R. ; Sorg, T. ; Wells, S. ; Fuchs, H. ; Fray, M. ; Adams, D.J. ; Adams, N.C. ; Adler, T. ; Aguilar-Pimentel, J.A. ; Ali-Hadji, D. ; Amann, G. ; André, P. ; Atkins, S. ; Auburtin, A. ; Ayadi, A. ; Becker, J. ; Becker, L. ; Bedu, E. ; Bekeredjian, R. ; Birling, M.C. ; Blake, A. ; Bottomley, J. ; Bowl, M.R. ; Brault, V. ; Busch, D.H. ; Bussell, J.N. ; Calzada-Wack, J. ; Cater, H. ; Champy, M.F. ; Charles, P. ; Chevalier, C. ; Chiani, F. ; Codner, G.F. ; Combe, R. ; Cox, R.D. ; Dalloneau, E. ; Dierich, A. ; di Fenza, A. ; Doe, B. ; Duchon, A. ; Eickelberg, O. ; Esapa, C.T. ; Fertak, L.E. ; Feigel, T. ; Emelyanova, I. ; Estabel, J. ; Favor, J. ; Flenniken, A.M. ; Gambadoro, A. ; Garrett, L. ; Gates, H. ; Gerdin, A.K. ; Gkoutos, G.V. ; Greenaway, S. ; Glasl, L. ; Goetz, P. ; da Cruz, I.G. ; Götz, A. ; Graw, J. ; Guimond, A. ; Hans, W. ; Hicks, G. ; Hölter, S.M. ; Höfler, H. ; Hancock, J.M. ; Hoehndorf, R. ; Hough, T. ; Houghton, R. ; Hurt, A. ; Ivandic, B. ; Jacobs, H. ; Jacquot, S. ; Jones, N. ; Karp, N.A. ; Katus, H.A. ; Kitchen, S. ; Klein-Rodewald, T. ; Klingenspor, M. ; Klopstock, T. ; Lalanne, V. ; Leblanc, S. ; Lengger, C. ; le Marchand, E. ; Ludwig, T. ; Lux, A. ; McKerlie, C. ; Maier, H. ; Mandel, J.L. ; Marschall, S. ; Mark, M. ; Melvin, D.G. ; Meziane, H. ; Micklich, K. ; Mittelhauser, C. ; Monassier, L. ; Moulaert, D. ; Müller, S. ; Naton, B. ; Neff, F. ; Nolan, P.M. ; Nutter, L.M. ; Ollert, M. ; Pavlovic, G. ; Pellegata, N.S. ; Peter, E. ; Petit-Demoulière, B. ; Pickard, A. ; Podrini, C. ; Potter, P. ; Pouilly, L. ; Puk, O. ; Richardson, D. ; Rousseau, S. ; Quintanilla-Fend, L. ; Quwailid, M.M. ; Rácz, I. ; Rathkolb, B. ; Riet, F. ; Rossant, J. ; Roux, M. ; Rozman, J. ; Ryder, E. ; Salisbury, J. ; Santos, L. ; Schäble, K.-H. ; Schiller, E. ; Schrewe, A. ; Schulz, H. ; Steinkamp, R. ; Simon, M. ; Stewart, M. ; Stoeger, C. ; Stöger, T. ; Sun, M. ; Sunter, D. ; Teboul, L. ; Tilly, I. ; Tocchini-Valentini, G.P. ; Tost, M. ; Treise, I. ; Vasseur, L. ; Velot, E. ; Vogt Weisenhorn, D.M. ; Wagner, C. ; Walling, A. ; Wattenhofer-Donze, M. ; Weber, B. ; Wendling, O. ; Westerberg, H. ; Willershäuser, M. ; Wolf, E. ; Wolter, A. ; Wood, J. ; Wurst, W. ; Yildirim, A.Ö. ; Zeh, R. ; Zimmer, A. ; Zimprich, A. ; Holmes, C. ; Steel, K.P. ; Herault, Y. ; Gailus-Durner, V. ; Mallon, A.M. ; Brown, S.D.
Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics.Beckervordersandforth, R. ; Ebert, B. ; Steib, K. ; Schaeffner, I. ; Keiner, S. ; Redecker, C. ; Schuster, S.C. ; Eulenburg, V. ; Toni, N. ; Moss, J. ; von Wittgenstein, J. ; Larsson, N.G. ; Götz, M. ; Schlachetzki, J. ; Jagasia, R. ; Lie, D.C.
Mitochondrial dysfunction mimics the impact of ageing on hippocampal neurogenesis.Deng, T. ; Zhu, Z.I. ; Zhang, S. ; Postnikov, Y. ; Huang, D. ; Horsch, M. ; Furusawa, T. ; Beckers, J. ; Rozman, J. ; Klingenspor, M. ; Amarie, O.V. ; Graw, J. ; Rathkolb, B. ; Wolf, E. ; Adler, T. ; Busch, D.H. ; Gailus-Durner, V. ; Fuchs, H. ; Hrabě de Angelis, M. ; van der Velde, A. ; Tessarollo, L. ; Ovcherenko, I. ; Landsman, D. ; Bustin, M.
Functional compensation among HMGN variants modulates the DNase I hypersensitive sites at enhancers.Theodorou, M. ; Rauser, B. ; Zhang, J. ; Prakash, N. ; Wurst, W. ; Schick, J.
Limitations of in vivo reprogramming to dopaminergic neurons via a tricistronic strategy.Jiang, Y. ; Sigmund, F. ; Reber, J. ; Dean-Ben, X.L. ; Glasl, S. ; Kneipp, M. ; Estrada, H. ; Razansky, D. ; Ntziachristos, V. ; Westmeyer, G.G.
Violacein as a genetically-controlled, enzymatically amplified and photobleaching-resistant chromophore for optoacoustic bacterial imaging.Truong, D.J.J. ; Kühner, K. ; Kühn, R. ; Werfel, S. ; Engelhardt, S. ; Wurst, W. ; Ortiz, O.
Development of an intein-mediated split-Cas9 system for gene therapy.Knauer-Arloth, J. ; Bogdan, R. ; Weber, P. ; Frishman, G. ; Menke, A. ; Wagner, K.V. ; Balsevich, G. ; Schmidt, M.V. ; Karbalai, N. ; Czamara, D. ; Altmann, A. ; Trümbach, D. ; Wurst, W. ; Mehta, D. ; Uhr, M. ; Klengel, T. ; Erhardt, A. ; Carey, C.E. ; Conley, E.D. ; Ruepp, A. ; Müller-Myhsok, B. ; Hariri, A.R. ; Binder, E.B.
Genetic differences in the immediate transcriptome response to stress predict risk-related brain function and psychiatric disorders.Saarikangas, J. ; Kourdougli, N. ; Senju, Y. ; Chazal, G. ; Segerstrale, M. ; Minkeviciene, R. ; Kuurne, J. ; Mattila, P.K. ; Garrett, L. ; Hölter, S.M. ; Becker, L. ; Rácz, I. ; Hans, W. ; Klopstock, T. ; Wurst, W. ; Zimmer, A. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; von Ossowski, L. ; Taira, T. ; Lappalainen, P. ; Rivera, C. ; Hotulainen, P.
MIM-induced membrane bending promotes dendritic spine initiation.Zhang, J. ; Götz, S. ; Vogt Weisenhorn, D.M. ; Simeone, A. ; Wurst, W. ; Prakash, N.
A WNT1-regulated developmental gene cascade prevents dopaminergic neurodegeneration in adult En1+/- mice.Scheerer, M.F.
Pharmacological and dietary interventions for the treatment of diabetes in mouse models.Wende, C.-Z. ; Zoubaa, S. ; Blak, A.A. ; Echevarria, D. ; Martinez, S. ; Guillemot, F. ; Wurst, W. ; Guimera, J.
Hairy/enhancer-of-split MEGANE and proneural MASH1 factors cooperate synergistically in midbrain GABAergic neurogenesis.Conrad, M. ; Friedmann Angeli, J.P.F.
Glutathione peroxidase 4 (Gpx4) and ferroptosis: What's so special about it?Kunze, S. ; Dalke, C. ; Fuchs, H. ; Klaften, M. ; Rössler, U. ; Hornhardt, S. ; Gomolka, M. ; Puk, O. ; Sabrautzki, S. ; Kulka, U. ; Hrabě de Angelis, M. ; Graw, J.
New mutation in the mouse Xpd/Ercc2 gene leads to recessive cataracts.Ingold, I. ; Aichler, M. ; Yefremova, E. ; Roveri, A. ; Buday, K. ; Doll, S. ; Tasdemir, A. ; Hoffard, N. ; Wurst, W. ; Walch, A.K. ; Ursini, F. ; Friedmann Angeli, J.P.F. ; Conrad, M.
Expression of a catalytically inactive mutant form of Glutathione peroxidase 4 (Gpx4) confers a dominant-negative effect in male fertility.Helmbrecht, M.S. ; Soellner, H. ; Castiblanco-Urbina, M.A. ; Winzeck, S. ; Sundermeier, J. ; Theis, F.J. ; Fouad, K. ; Huber, A.B.
A critical period for postnatal adaptive plasticity in a model of motor axon miswiring.Labazi, M. ; McNeil, A.K. ; Kurtz, T. ; Lee, T.C. ; Pegg, R.B. ; Friedmann Angeli, J.P.F. ; Conrad, M. ; McNeil, P.L.
The antioxidant requirement for plasma membrane repair in skeletal muscle.Andjelić, S. ; Drašlar, K. ; Lumi, X. ; Yan, X. ; Graw, J. ; Facskó, A. ; Hawlina, M. ; Petrovski, G.
Morphological and proliferative studies on ex vivo cultured human anterior lens epithelial cells - relevance to capsular opacification.Riemer, J. ; Schwarzländer, M. ; Conrad, M. ; Herrmann, J.M.
Thiol switches in mitochondria: Operation and physiological relevance.Hellfritsch, J. ; Kirsch, J. ; Schneider, M. ; Fluege, T. ; Wortmann, M. ; Frijhoff, J. ; Dagnell, M. ; Fey, T. ; Esposito, I. ; Kölle, P. ; Pogoda, K. ; Ingold, I. ; Friedmann Angeli, J.P.F. ; Kuhlencordt, P. ; Östman, A. ; Pohl, U. ; Beck, H. ; Conrad, M.
Knockout of mitochondrial thioredoxin reductase stabilizes prolyl hydroxylase 2 and inhibits tumor growth and tumor-derived angiogenesis.Matsushita, M. ; Freigang, S. ; Schneider, C. ; Conrad, M. ; Bornkamm, G.W. ; Kopf, M.
T cell lipid peroxidation induces ferroptosis and prevents immunity to infection.Mellett, M. ; Atzei, P. ; Bergin, R. ; Horgan, A. ; Floß, T. ; Wurst, W. ; Callanan, J.J. ; Moynagh, P.N.
Orphan receptor IL-17RD regulates toll-like receptor signalling via SEFIR/TIR interactions.Chu, V.T. ; Weber, T. ; Wefers, B. ; Wurst, W. ; Sander, S. ; Rajewsky, K. ; Kühn, R.
Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells.Kobayashi, S. ; Sato, M. ; Kasakoshi, T. ; Tsutsui, T. ; Sugimoto, M. ; Osaki, M. ; Okada, F. ; Igarashi, K. ; Hiratake, J. ; Homma, T. ; Conrad, M. ; Fujii, J. ; Soga, T. ; Bannai, S. ; Sato, H.
Cystathionine is a novel substrate of cystine/glutamate transporter: Implications for immune function.Kessler, T. ; Zhang, L. ; Liu, Z. ; Yin, X. ; Huang, Y. ; Wang, Y. ; Fu, Y. ; Mayr, M. ; Ge, Q. ; Xu, Q. ; Zhu, Y. ; Wang, X. ; Schmidt, K.J. ; de Wit, C. ; Erdmann, J. ; Schunkert, H. ; Aherrahrou, Z ; Kong, W. ; German Mouse Clinic Consortium (Adamski, J. ; Adler, T. ; Aguilar-Pimentel, J.A. ; Amarie, O.V. ; Becker, L. ; Beckers, J. ; Brachthäuser, L. ; Busch, D.H. ; Calzada-Wack, J. ; Eickelberg, O. ; Fuchs, H. ; Gailus-Durner, V. ; Garrett, L. ; Graw, J. ; Hans, W. ; Hölter, S.M. ; Horsch, M. ; Hrabě de Angelis, M. ; Janik, D. ; Klein-Rodewald, T. ; Klingenspor, M. ; Klopstock, T. ; Lengger, C. ; Leuchtenberger, S. ; Maier, H. ; Moreth, K. ; Neff, F. ; Ollert, M. ; Prehn, C. ; Puk, O. ; Rathkolb, B. ; Rozman, J. ; Steinkamp, R. ; Stoeger, C. ; Stöger, T. ; Vernaleken, A. ; Yildirim, A.Ö. ; Wurst, W. ; Zimprich, A.)
ADAMTS-7 inhibits re-endothelialization of injured arteries and promotes vascular remodeling via cleavage of thrombospondin-1.Hüttl, R.E. ; Luxenhofer, G. ; Bianchi, E. ; Haupt, C. ; Joshi, R. ; Prochiantz, A. ; Huber, A.B.
Engrailed 1 mediates correct formation of limb innervation through two distinct mechanisms.Stiel, A.C. ; Dean-Ben, X.L. ; Jiang, Y. ; Ntziachristos, V. ; Razansky, D. ; Westmeyer, G.G.
High-contrast imaging of reversibly switchable fluorescent proteins via temporally unmixed multispectral optoacoustic tomography.Kagan, V.E. ; Tyurina, Y.Y. ; Tyurin, V.A. ; Mohammadyani, D. ; Friedmann Angeli, J.P.F. ; Baranov, S.V. ; Klein-Seetharaman, J. ; Friedlander, R.M. ; Mallampalli, R.K. ; Conrad, M. ; Bayir, H.
Cardiolipin signaling mechanisms: Collapse of asymmetry and oxidation.Vogl, A.M. ; Brockmann, M.M. ; Giusti, S.A. ; Maccarrone, G. ; Vercelli, C.A. ; Bauder, C.A. ; Richter, J.S. ; Roselli, F. ; Hafner, A.S. ; Dedic, N. ; Wotjak, C.T. ; Vogt Weisenhorn, D.M. ; Choquet, D. ; Turck, C.W. ; Stein, V. ; Deussing, J.M. ; Refojo, D.
Neddylation inhibition impairs spine development, destabilizes synapses and deteriorates cognition.Tischner, C. ; Hofer, A. ; Wulff, V. ; Stepek, J. ; Dumitru, I. ; Becker, L. ; Haack, T.B. ; Kremer, L.S. ; Datta, A.N. ; Sperl, W. ; Floß, T. ; Wurst, W. ; Chrzanowska-Lightowlers, Z.M. ; Hrabě de Angelis, M. ; Klopstock, T. ; Prokisch, H. ; Wenz, T.
MTO1 mediates tissue-specificity of OXPHOS defects via tRNA modification and translation optimization, which can be bypassed by dietary intervention.Washkowitz, A.J. ; Schall, C. ; Zhang, K.L. ; Wurst, W. ; Floß, T. ; Mager, J. ; Papaioannou, V.E.
Mga is essential for the survival of pluripotent cells during peri-implantation development.Brandl, C. ; Ortiz, O. ; Röttig, B. ; Wefers, B. ; Wurst, W. ; Kühn, R.
Creation of targeted genomic deletions using TALEN or CRISPR/Cas nuclease pairs in one-cell mouse embryos.Song, H. ; Lee, B. ; Pyun, D. ; Guimera, J. ; Son, Y. ; Yoon, J. ; Baek, K. ; Wurst, W. ; Jeong, Y.
Ascl1 and Helt act combinatorially to specify thalamic neuronal identity by repressing Dlxs activation.Helmbrecht, M.S. ; Soellner, H. ; Truckenbrodt, A.M. ; Sundermeier, J. ; Cohrs, C.M. ; Hans, W. ; Hrabě de Angelis, M. ; Feuchtinger, A. ; Aichler, M. ; Fouad, K. ; Huber, A.B.
Loss of Npn1 from motor neurons causes postnatal deficits independent from Sema3A signaling.Cremer, J.N. ; Amunts, K. ; Graw, J. ; Piel, M. ; Rösch, F. ; Zilles, K.
Neurotransmitter receptor density changes in Pitx3AK mice - a model relevant to Parkinson's disease.Conrad, M. ; Ingold, I. ; Buday, K. ; Kobayashi, S. ; Friedmann Angeli, J.P.F.
ROS, thiols and thiol-regulating systems in male gametogenesis.Seyfarth, K. ; Poschmann, G. ; Rozman, J. ; Fromme, T. ; Rink, N. ; Hofmann, A. ; Wurst, W. ; Stühler, K. ; Klingenspor, M.
The development of diet-induced obesity and associated metabolic impairments in Dj-1 deficient mice.Keeney, J.G. ; O'Bleness, M.S. ; Anderson, N. ; Davis, J.M. ; Arevalo, N. ; Busquet, N. ; Chick, W. ; Rozman, J. ; Hölter, S.M. ; Garrett, L. ; Horsch, M. ; German Mouse Clinic Consortium (Adler, T. ; Aguilar-Pimentel, J.A. ; Amarie, O.V. ; Eickelberg, O. ; Gailus-Durner, V. ; Graw, J. ; Hans, W. ; Horsch, M. ; Janik, D. ; Neff, F. ; Ollert, M. ; Puk, O. ; Rácz, I. ; Rathkolb, B. ; Stöger, T. ; Yildirim, A.Ö.) ; Beckers, J. ; Wurst, W. ; Klingenspor, M. ; Restrepo, D. ; Sikela, J.M. ; Hrabě de Angelis, M.
Generation of mice lacking DUF1220 protein domains: Effects on fecundity and hyperactivity.Knier, B. ; Rothhammer, V. ; Heink, S. ; Puk, O. ; Graw, J. ; Hemmer, B. ; Korn, T.
Neutralizing IL-17 protects the optic nerve from autoimmune pathology and prevents retinal nerve fiber layer atrophy during experimental autoimmune encephalomyelitis.Neschen, S. ; Scheerer, M. ; Seelig, A. ; Huypens, P. ; Schultheiss, J. ; Wu, M. ; Wurst, W. ; Rathkolb, B. ; Suhre, K. ; Wolf, E. ; Beckers, J. ; Hrabě de Angelis, M.
Metformin supports the antidiabetic effect of a sodium glucose cotransporter 2 inhibitor by suppressing endogenous glucose production in diabetic mice.Trümbach, D. ; Prakash, N.
The conserved miR-8/miR-200 microRNA family and their role in invertebrate and vertebrate neurogenesis.O'Flanagan, C.H. ; Morais, V.A. ; Wurst, W. ; de Strooper, B. ; O'Neill, C.
The Parkinson's gene PINK1 regulates cell cycle progression and promotes cancer-associated phenotypes.Friedmann Angeli, J.P.F. ; Proneth, B. ; Hammond, V.J. ; Tyurina, Y.Y. ; Tyurin, V.A. ; O'Donnell, V.B. ; Kagan, V.E. ; Conrad, M.
Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in a therapeutically relevant mechanism.Götz, S.
Die Rolle des Wnt/ß-Catenin-Signalweges bei der Entwicklung meso-diencephalisch dopaminerger Neuronen.Karaca, E.
Role of Sp transcription factors in adult neurogenesis.Aprile-Garcia, F. ; Metzger, M.W. ; Dedic, N. ; Walser, S.M. ; Jakubcakova, V. ; Czamara, D. ; Mitkovski, M. ; Müller-Myhsok, B. ; Kimura, M. ; Wurst, W. ; Stuehmer, W. ; Holsboer, F. ; Arzt, E. ; Deussing, J.M.
P2RX7-a susceptibility gene for mood disorders?Matsui, H. ; Namikawa, K. ; Köster, R.W.
Identification of the zebrafish red nucleus using wheat germ agglutinin transneuronal tracing.Meier, F.
Signaling pathways in mesodiencephalic dopaminergic and cerebellar neural development in vitro and in vivo.Panda, S.
Establishment of mouse disease models by using sequence specific nucleases.Häberle, M.-T. ; Kelsch, E. ; Dorsch, K. ; Möller, P. ; Ritz, O.
Knock-down of BCL6 / STAT6 sensitizes primary B cell lymphoma cells for treatment with current therapeutic agents.Andjeli, S. ; Lumi, X. ; Yan, X. ; Graw, J. ; Moe, M.C. ; Facskó, A. ; Hawlina, M. ; Petrovski, G.
Characterization of ex vivo cultured neuronal- and glial- like cells from human idiopathic epiretinal membranes.Becker, L. ; Kling, E. ; Schiller, E. ; Zeh, R. ; Schrewe, A. ; Hölter, S.M. ; Mossbrugger, I. ; Calzada-Wack, J. ; Strecker, V. ; Wittig, I. ; Dumitru, I. ; Wenz, T. ; Bender, A. ; Aichler, M. ; Janik, D. ; Neff, F. ; Walch, A.K. ; Quintanilla-Fend, L. ; Floß, T. ; Bekeredjian, R. ; Gailus-Durner, V. ; Fuchs, H. ; Wurst, W. ; Meitinger, T. ; Prokisch, H. ; Hrabě de Angelis, M. ; Klopstock, T.
MTO1-deficient mouse model mirrors the human phenotype showing complex I defect and cardiomyopathy.Schäffner, I.
Fox transcription factors in adult neurogenesis.Brockmann, M.
Nedd8 in the brain - Its impact on synaptic function and the role of PSD-95.Symvoulidis, P. ; Cruz Perez, C. ; Schwaiger, M. ; Ntziachristos, V. ; Westmeyer, G.G.
Serial sectioning and mulstispectral imaging system for versatile biomedical applications.Gewies, A. ; Gorka, O. ; Bergmann, H. ; Pechloff, K. ; Petermann, F. ; Jeltsch, K. ; Rudelius, M. ; Kriegsmann, M. ; Weichert, W. ; Horsch, M. ; Beckers, J. ; Wurst, W. ; Heikenwälder, M. ; Korn, T. ; Heissmeyer, V. ; Ruland, J.
Uncoupling Malt1 threshold function from paracaspase activity results in destructive autoimmune inflammation.Giusti, S.A. ; Vogl, A.M. ; Brockmann, M.M. ; Vercelli, C.A. ; Rein, M.L. ; Trümbach, D. ; Wurst, W. ; Cazalla, D. ; Stein, V. ; Deussing, J.M. ; Refojo, D.
MicroRNA-9 controls dendritic development by targeting REST.Friedmann Angeli, J.P.F. ; Schneider, M. ; Proneth, B. ; Tyurina, Y.Y. ; Tyurin, V.A. ; Hammond, V.J. ; Herbach, N. ; Aichler, M. ; Walch, A.K. ; Eggenhofer, E. ; Basavarajappa, D. ; Rådmark, O. ; Kobayashi, S. ; Seibt, T. ; Beck, H. ; Neff, F. ; Esposito, I. ; Wanke, R. ; Förster, H. ; Yefremova, O. ; Heinrichmeyer, M. ; Bornkamm, G.W. ; Geissler, E.K. ; Thomas, S.B. ; Stockwell, B.R. ; O'Donnell, V.B. ; Kagan, V.E. ; Schick, J. ; Conrad, M.
Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice.Ramin, M. ; Bürger, A. ; Hörlein, A. ; Kerkau, D. ; von Walcke-Wulffen, V. ; Nicklas, W. ; Schenkel, J.
Stability of cryopreserved samples of mutant mice.Thor, T. ; Künkele, A. ; Pajtler, K.W. ; Wefers, A.K. ; Stephan, H. ; Mestdagh, P. ; Heukamp, L. ; Hartmann, W. ; Vandesompele, J. ; Sadowski, N. ; Becker, L. ; Garrett, L. ; Hölter, S.M. ; Horsch, M. ; Calzada-Wack, J. ; Klein-Rodewald, T. ; Rácz, I. ; Zimmer, A. ; Beckers, J. ; Neff, F. ; Klopstock, T. ; de Antonellis, P. ; Zollo, M. ; Wurst, W. ; Fuchs, H. ; Gailus-Durner, V. ; Schüller, U. ; Hrabě de Angelis, M. ; Eggert, A. ; Schramm, A. ; Schulte, J.H.
MiR-34a deficiency accelerates medulloblastoma formation in vivo.Wefers, B. ; Ortiz, O. ; Wurst, W. ; Kühn, R.
Generation of targeted mouse mutants by embryo microinjection of TALENs.Sotnikov, S.V. ; Chekmareva, N.Y. ; Schmid, B. ; Harbich, D. ; Malik, V. ; Bauer, S. ; Kuehne, C. ; Markt, P.O. ; Deussing, J.M. ; Schmidt, M.V. ; Landgraf, R.
Enriched environment impacts trimethylthiazoline-induced anxiety-related behavior and immediate early gene expression: Critical role of Crhr1.Kühn, R. ; Wefers, B.
Editing and investigating genomes with TALE and CRISPR/Cas systems: Genome engineering across species using TALENs.Kühn, R. ; Brandl, C. ; Ortiz, O. ; Wurst, W.
Generation of targeted deletions in mouse zygotes by pairs of TALENs or SGRNAS/Cas9.Tiedemann, H.B. ; Schneltzer, E. ; Zeiser, S. ; Wurst, W. ; Beckers, J. ; Przemeck, G.K.H. ; Hrabě de Angelis, M.
Fast synchronization of ultradian oscillators controlled by Delta-Notch signaling with Cis-inhibition.Kandasamy, M. ; Lehner, B. ; Kraus, S. ; Sander, P.R. ; Marschallinger, J. ; Rivera, F.J. ; Trümbach, D. ; Ueberham, U. ; Reitsamer, H.A. ; Strauss, O. ; Bogdahn, U. ; Couillard-Despres, S. ; Aigner, L.
TGF-beta signalling in the adult neurogenic niche promotes stem cell quiescence as well as generation of new neurons.Schötz, U. ; Deliolanis, N. ; Ng, D. ; Pauli, J. ; Resch-Genger, U. ; Kühn, E. ; Heuer, S. ; Beisker, W. ; Köster, R.W. ; Zitzelsberger, H. ; Caldwell, R.B.
Usefulness of a darwinian system in a biotechnological application: Evolution of optical window fluorescent protein variants under selective pressure.Matthes, M. ; Preusse, M. ; Zhang, J. ; Schechter, J. ; Mayer, D. ; Lentes, B. ; Theis, F.J. ; Prakash, N. ; Wurst, W. ; Trümbach, D.
Mouse IDGenes: A reference database for genetic interactions in the developing mouse brain.Nehls, J. ; Koppensteiner, H. ; Brack-Werner, R. ; Floß, T. ; Schindler, M.
HIV-1 replication in human immune cells is independent of TAR DNA binding Protein 43 (TDP-43) expression.Kraus, P. ; Sivakamasundari, V. ; Yu, H.B. ; Xing, X. ; Lim, S.L. ; Adler, T. ; Aguilar-Pimentel, J.A. ; Becker, L. ; Bohla, A. ; Garrett, L. ; Hans, W. ; Hölter, S.M. ; Janas, E. ; Moreth, K. ; Prehn, C. ; Puk, O. ; Rathkolb, B. ; Rozman, J. ; Adamski, J. ; Bekeredjian, R. ; Busch, D.H. ; Graw, J. ; Klingenspor, M. ; Klopstock, T. ; Neff, F. ; Ollert, M. ; Stöger, T. ; Yildirim, A.Ö. ; Eickelberg, O. ; Wolf, E. ; Wurst, W. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Lufkin, T. ; Stanton, L.W.
Pleiotropic functions for transcription factor Zscan10.Kemter, E. ; Rathkolb, B. ; Becker, L. ; Bolle, I. ; Busch, D.H. ; Dalke, C. ; Elvert, R. ; Favor, J. ; Graw, J. ; Hans, W. ; Ivandic, B. ; Kaladydjiev, S. ; Klopstock, T. ; Rácz, I. ; Rozman, J. ; Schrewe, A. ; Schulz, H. ; Zimmer, A. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Wolf, E. ; Aigner, B.
Standardized, systemic phenotypic analysis of Slc12a1 I299F mutant mice.Floß, T.
Reply to Jawaid et al.: Mitochondrial dysfunction and decrease in body weight of transgenic knock-in mouse model for TDP-43: The question of glucose?.Blanco, S. ; Dietmann, S. ; Flores, J.V. ; Hussain, S. ; Kutter, C. ; Humphreys, P. ; Lukk, M. ; Lombard, P. ; Treps, L. ; Popis, M. ; Kellner, S. ; Hölter, S.M. ; Garrett, L. ; Wurst, W. ; Becker, L. ; Klopstock, T. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Káradóttir, R.T. ; Helm, M. ; Ule, J. ; Gleeson, J.G. ; Odom, D.T. ; Frye, M.
Aberrant methylation of tRNAs links cellular stress to neuro-developmental disorders.Toyoda, Y. ; Erkut, C. ; Pan-Montojo, F. ; Boland, S. ; Stewart, M.P. ; Müller, D.J. ; Wurst, W. ; Hyman, A.A. ; Kurzchalia, T.V.
Products of the Parkinson's disease-related glyoxalase DJ-1, D-lactate and glycolate, support mitochondrial membrane potential and neuronal survival.Matsui, H. ; Namikawa, K. ; Babaryka, A. ; Köster, R.W.
Functional regionalization of the teleost cerebellum analyzed in vivo.Sotnikov, S. ; Wittmann, A. ; Bunck, M. ; Bauer, S. ; Deussing, J.M. ; Schmidt, M. ; Touma, C. ; Landgraf, R. ; Czibere, L.
Blunted HPA axis reactivity reveals glucocorticoid system dysbalance in a mouse model of high anxiety-related behavior.Meier, F. ; Giesert, F. ; Delic, S. ; Faus-Kessler, T. ; Matheus, F. ; Simeone, A. ; Hölter, S.M. ; Kühn, R. ; Vogt Weisenhorn, D.M. ; Wurst, W. ; Prakash, N.
FGF/FGFR2 signaling regulates the generation and correct positioning of Bergmann glia cells in the developing mouse cerebellum.Lewerenz, J. ; Baxter, P.S. ; Kassubek, R. ; Albrecht, P. ; van Liefferinge, J. ; Westhoff, M.A. ; Halatsch, M.E. ; Karpel-Massler, G. ; Meakin, P.J. ; Hayes, J.D. ; Aronica, E.M. ; Smolders, I. ; Ludolph, A.C. ; Methner, A. ; Conrad, M. ; Massie, A. ; Hardingham, G.E. ; Maher, P.A.
Phosphoinositide 3-kinases upregulate system xc - via eukaryotic initiation factor 2α and activating transcription factor 4-A pathway active in glioblastomas and epilepsy.Marzaioli, V. ; Aguilar-Pimentel, J.A. ; Weichenmeier, I. ; Luxenhofer, G. ; Wiemann, M. ; Landsiedel, R. ; Wohlleben, W. ; Eiden, S. ; Mempel, M. ; Behrendt, H. ; Schmidt-Weber, C.B. ; Gutermuth, J. ; Alessandrini, F.
Surface modifications of silica nanoparticles are crucial for their inert versus proinflammatory and immunomodulatory properties.Zumbrennen-Bullough, K.B. ; Becker, L. ; Garrett, L. ; Hölter, S.M. ; Calzada-Wack, J. ; Mossbrugger, I. ; Quintanilla-Fend, L. ; Rácz, I. ; Rathkolb, B. ; Klopstock, T. ; Wurst, W. ; Zimmer, A. ; Wolf, E. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Romney, S.J. ; Leibold, E.A.
Abnormal brain iron metabolism in Irp2 deficient mice is associated with mild neurological and behavioral impairments.Yan, X. ; Sabrautzki, S. ; Horsch, M. ; Fuchs, H. ; Gailus-Durner, V. ; Beckers, J. ; Hrabě de Angelis, M. ; Graw, J.
Peroxidasin is essential for eye development in the mouse.Schulte, E.C. ; Schramm, K. ; Schurmann, C. ; Lichtner, P. ; Herder, C. ; Roden, M. ; Gieger, C. ; Peters, A. ; Trenkwalder, C. ; Högl, B. ; Frauscher, B. ; Berger, K. ; Fietze, I. ; Gross, N. ; Stiasny-Kolster, K. ; Oertel, W. ; Bachmann, C.G. ; Paulus, W. ; ; Völzke, H. ; Schminke, U. ; Nauck, M. ; Illig, T. ; Meitinger, T. ; Müller-Myhsok, B. ; Prokisch, H. ; Winkelmann, J.
Blood cis-eQTL analysis fails to identify novel association signals among sub-threshold candidates from genome-wide association studies in restless legs syndrome.Huang, H. ; Koelle, P. ; Fendler, M. ; Schröttle, A. ; Czihal, M. ; Hoffmann, U. ; Conrad, M. ; Kuhlencordt, P.J.
Induction of inducible Nitric Oxide Synthase (iNOS) expression by oxLDL inhibits macrophage derived foam cell migration.Peng, X. ; Mandal, P.K. ; Kaminskyy, V.O. ; Lindqvist, A. ; Conrad, M. ; Arner, E.S.J.
Sec-containing TrxR1 is essential for self-sufficiency of cells by control of glucose-derived H2O2.Wirth, E.K. ; Bharathi, B.S. ; Hatfield, D.L. ; Conrad, M. ; Brielmeier, M. ; Schweizer, U.
Cerebellar hypoplasia in mice lacking selenoprotein biosynthesis in neurons.Steib, K. ; Schäffner, I. ; Jagasia, R. ; Ebert, B. ; Lie, D.C.
Mitochondria modify exercise-induced development of stem cell-derived neurons in the adult brain.Hüttl, R.E. ; Huber, A.B.
Quantitative analysis of axonal outgrowth in mice.Zimprich, A. ; Garett, L. ; Deussing, J.M. ; Wotjak, C.T. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Wurst, W. ; Hölter, S.M.
A robust and reliable non-invasive test for stress responsivity in mice.Moreth, K. ; Fischer, R. ; Fuchs, H. ; Gailus-Durner, V. ; Wurst, W. ; Katus, H.A. ; Bekeredjian, R. ; Hrabě de Angelis, M.
High-throughput phenotypic assessment of cardiac physiology in four commonly used inbred mouse strains.Dykes, I.M. ; van Bueren, K.L. ; Ashmore, R.J. ; Floß, T. ; Wurst, W. ; Szumska, D. ; Bhattacharya, S. ; Scambler, P.J.
HIC2 is a novel dosage-dependent regulator of cardiac development located within the distal 22q11 deletion syndrome region.Piccoli, G. ; Onofri, F. ; Cirnaru, M.D. ; Kaiser, C.J. ; Jagtap, P.K. ; Kastenmüller, A. ; Pischedda, F. ; Marte, A. ; von Zweydorf, F. ; Vogt, A. ; Giesert, F. ; Pan, L. ; Antonucci, F. ; Kiel, C. ; Zhang, M. ; Weinkauf, S. ; Sattler, M. ; Sala, C. ; Matteoli, M. ; Ueffing, M. ; Gloeckner, C.J.
Leucine-rich repeat kinase 2 binds to neuronal vesicles through protein interactions mediated by its C-terminal WD40 domain.Pertek, A. ; Meier, F. ; Irmler, M. ; Beckers, J. ; Skylaki, S. ; Endele, M. ; Wurst, W. ; Prakash, N. ; Kühn, R.
Simple derivation of transgene-free iPS cells by a dual recombinase approach.Poschmann, G. ; Seyfarth, K. ; Besong Agbo, D. ; Klafki, H.-W. ; Rozman, J. ; Wurst, W. ; Wiltfang, J. ; Meyer, H.E. ; Klingenspor, M. ; Stühler, K.
High fat diet induced isoform changes of the Parkinson’s disease protein DJ-1.Westmeyer, G.G. ; Emer, Y. ; Lintelmann, J. ; Jasanoff, A.
MRI-based detection of alkaline phosphatase gene reporter activity using a porphyrin solubility switch.Spieler, D. ; Kaffe, M. ; Knauf, F. ; Bessa, J. ; Tena, J.J. ; Giesert, F. ; Schormair, B. ; Tilch, E. ; Lee, H. ; Horsch, M. ; Czamara, D. ; Karbalai, N. ; von Toerne, C. ; Waldenberger, M. ; Gieger, C. ; Lichtner, P. ; Claussnitzer, M. ; Naumann, R. ; Müller-Myhsok, B. ; Torres, M. ; Garrett, L. ; Rozman, J. ; Klingenspor, M. ; Gailus-Durner, V. ; Fuchs, H. ; Hrabě de Angelis, M. ; Beckers, J. ; Hölter, S.M. ; Meitinger, T. ; Hauck, S.M. ; Laumen, H. ; Wurst, W. ; Casares, F. ; Gómez-Skarmeta, J.L. ; Winkelmann, J.
Restless Legs Syndrome-associated intronic common variant in Meis1 alters enhancer function in the developing telencephalon.Pischedda, F. ; Szczurkowska, J. ; Cirnaru, M.D. ; Giesert, F. ; Vezzoli, E. ; Ueffing, M. ; Sala, C. ; Francolini, M. ; Hauck, S.M. ; Cancedda, L. ; Piccoli, G.
A cell surface biotinylation assay to reveal membrane-associated neuronal cues: Negr1 regulates dendritic arborization.Beckervordersandforth, R. ; Deshpande, A. ; Schäffner, I. ; Huttner, H.B. ; Lepier, A. ; Lie, D.C. ; Götz, M.
In vivo targeting of adult neural stem cells in the dentate gyrus by a split-cre approach.Stribl, C.B. ; Samara, A. ; Trümbach, D. ; Augustin, R. ; Neumann, M. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Rathkolb, B. ; Wolf, E. ; Beckers, J. ; Horsch, M. ; Neff, F. ; Kremmer, E. ; Koob, S. ; Reichert, A.S. ; Hans, W. ; Rozman, J. ; Klingenspor, M. ; Aichler, M. ; Walch, A.K. ; Becker, L. ; Klopstock, T. ; Glasl, L. ; Hölter, S.M. ; Wurst, W. ; Floß, T.
Mitochondrial dysfunction and decrease in body weight of a transgenic knock-in mouse model for TDP-43.Polzer, H. ; Volkmer, E. ; Saller, M. ; Prall, W.C. ; Haasters, F. ; Drosse, I. ; Wilhelmi, A. ; Mutschler, W. ; Schieker, M.
Comparison of different strategies for in vivo seeding of prevascularized scaffolds.Tripathi, P.P. ; Giovannantonio, L.G. ; Sanguinetti, E. ; Acampora, D. ; Allegra, M. ; Caleo, M. ; Wurst, W. ; Simeone, A. ; Bozzi, Y.
Increased dopaminergic innervation in the brain of conditional mutant mice overexpressing Otx2: Effects on locomotor behaviour and seizure susceptibility.di Giovannantonio, L.G. ; di Salvio, M. ; Omodei, D. ; Prakash, N. ; Wurst, W. ; Pierani, A. ; Acampora, D. ; Simeone, A.
Otx2 cell-autonomously determines dorsal mesencephalon versus cerebellum fate independently of isthmic organizing activity.Luxenhofer, G. ; Helmbrecht, M.S. ; Langhoff, J. ; Giusti, S.A. ; Refojo, D. ; Huber, A.B.
MicroRNA-9 promotes the switch from early-born to late-born motor neuron populations by regulating Onecut transcription factor expression.Wurst, W. ; Prakash, N.
Wnt1-regulated genetic networks in midbrain dopaminergic neuron development.Kirchner, M. ; Fegg, W. ; Römmelt, H. ; Leuchner, M. ; Ries, L. ; Zimmermann, R. ; Michalke, B. ; Wallasch, M. ; Maguhn, J. ; Faus-Kessler, T. ; Jakobi, G.
Nitrogen deposition along differently exposed slopes in the Bavarian Alps.Yan, X.
The role of Peroxidasin and Bmpr1b in eye development and diseases.Floß, T. ; Guimera, J.
Targeted Mutagenesis, Mouse.Guimera, J. ; Floß, T.
Genetics nomenclature, mouse.Puk, O. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Graw, J.
The eye screen of the German Mouse Clinic (GMC) - new genetic insights into eye development and ocular disorders.Graw, J. ; Strobl, R. ; Heier, M. ; Linkohr, B. ; Peters, A. ; Holle, R. ; Grill, E.
The KORA-AGE eye study: Eye diseases in the elderly.Flinn, L.J. ; Keatinge, M. ; Bretaud, S. ; Mortiboys, H. ; Matsui, H. ; de Felice, E. ; Woodroof, H.I. ; Brown, L. ; McTighe, A. ; Soellner, R. ; Allen, C.E. ; Heath, P.R. ; Milo, M. ; Muqit, M.M.K. ; Reichert, A.S. ; Köster, R.W. ; Ingham, P.W. ; Bandmann, O.
TigarB causes mitochondrial dysfunction and neuronal loss in PINK1 deficiency.Kuruthukulangarakoola, G.T. ; Lindermayr, C.
Regulation and function of protein S-nitrosylation in plant stress.Frankó, A. ; Baris, O.R. ; Bergschneider, E. ; von Toerne, C. ; Hauck, S.M. ; Aichler, M. ; Walch, A.K. ; Wurst, W. ; Wiesner, R.J. ; Johnston, I.C.D. ; Hrabě de Angelis, M.
Efficient isolation of pure and functional mitochondria from mouse tissues using automated tissue disruption and enrichment with anti-TOM22 magnetic beads.Wefers, B. ; Panda, S. ; Ortiz, O. ; Brandl, C. ; Hensler, S. ; Hansen, J. ; Wurst, W. ; Kühn, R.
Generation of targeted mouse mutants by embryo microinjection of TALEN mRNA.Ahmad, N. ; Aslam, M. ; Münster, D. ; Horsch, M. ; Khan, M.A. ; Carlsson, P. ; Beckers, J. ; Graw, J.
Pitx3 directly regulates Foxe3 during early lens development.Spanagel, R. ; Durstewitz, D. ; Hansson, A. ; Heinz, A. ; Kiefer, F. ; Köhr, G. ; Matthäus, F. ; Nöthen, M.M. ; Noori, H.R. ; Obermayer, K. ; Rietschel, M. ; Schloss, P. ; Scholz, H. ; Schumann, G. ; Smolka, M. ; Sommer, W. ; Vengeliene, V. ; Walter, H. ; Wurst, W. ; Zimmermann, U. ; Addiction GWAS Resource Group (Stringer, S. ; Smits, Y. ; Derks, E.M.)
A systems medicine research approach for studying alcohol addiction.Manzoni, C. ; Mamais, A. ; Dihanich, S. ; McGoldrick, P. ; Devine, M.J. ; Zerle, J. ; Kara, E. ; Taanman, J.W. ; Healy, D.G. ; Marti-Masso, J.F. ; Schapira, A.H. ; Plun-Favreau, H. ; Tooze, S. ; Hardy, J. ; Bandopadhyay, R. ; Lewis, P.A.
Pathogenic Parkinson's disease mutations across the functional domains of LRRK2 alter the autophagic/lysosomal response to starvation.Kim, J. ; Badaloni, A. ; Willert, T. ; Zimber-Strobl, U. ; Kühn, R. ; Wurst, W. ; Kieslinger, M.
An RNAi-based approach to down-regulate a gene family in vivo.Hölter, S.M. ; Stromberg, M. ; Kovalenko, M. ; Garrett, L. ; Glasl, L. ; Lopez, E. ; Guide, J. ; Götz, A. ; Hans, W. ; Becker, L. ; Rathkolb, B. ; Rozman, J. ; Schrewe, A. ; Klingenspor, M. ; Klopstock, T. ; Schulz, H. ; Wolf, E. ; Wurst, W. ; Gillis, T. ; Wakimoto, H. ; Seidmann, J. ; MacDonald, M.E. ; Cotman, S.L. ; Gailus-Durner, V. ; Fuchs, H. ; Hrabě de Angelis, M. ; Lee, J.M. ; Wheeler, V.C.
A broad phenotypic screen identifies novel phenotypes driven by a single mutant allele in Huntington’s diesease CAG knock-in mice.Meyer, M.
Gezielte Genmodifikation in Mauszygoten durch sequenzspezifische Nukleasen.Steib, K.
The function of mitochondrial dynamics, content and localization during adult hippocampal neurogenesis.Panda, S. ; Wefers, B. ; Ortiz, O. ; Floß, T. ; Schmid, B. ; Haass, C. ; Wurst, W. ; Kühn, R.
Highly efficient targeted mutagenesis in mice using TALENs.Kleinhammer, A. ; Wurst, W. ; Kühn, R.
Target validation in mice by constitutive and conditional RNAi.Besong Agbo, D. ; Klafki, H. ; Poschmann, G. ; Genius, J. ; Janßen, C. ; Stühler, K. ; Wurst, W. ; Meyer, H.E. ; Klingenspor, M. ; Wiltfang, J.
Development of a capillary isoelectric focusing immunoassay to measure DJ-1 isoforms in biological samples.Häbig, K. ; Gellhaar, S. ; Heim, B. ; Djuric, V. ; Giesert, F. ; Wurst, W. ; Walter, C. ; Hentrich, T. ; Riess, O. ; Bonin, M.
LRRK2 guides the actin cytoskeleton at growth cones together with ARHGEF7 and Tropomyosin 4.Sun, M. ; Hölter, S.M. ; Stepan, J. ; Garrett, L. ; Genius, J. ; Kremmer, E. ; Hrabě de Angelis, M. ; Wurst, W. ; Lie, D.C. ; Bally-Cuif, L. ; Eder, M. ; Rujescu, D. ; Graw, J.
Crybb2 coding for βB2-crystallin affects sensorimotor gating and hippocampal function.Andréasson, C. ; Schick, A.J. ; Pfeiffer, S.M. ; Sarov, M. ; Stewart, F. ; Wurst, W. ; Walcher, T.
Direct cloning of isogenic murine DNA in yeast and relevance of isogenicity for targeting in embryonic stem cells.Kloos, K.
The role of PINK1 in the pathoethiology of Parkinson's disease.Dagnell, M. ; Frijhoff, J. ; Pader, I. ; Augsten, M. ; Boivin, B. ; Xu, J.Q. ; Mandal, P.K. ; Tonks, N.K. ; Hellberg, C. ; Conrad, M. ; Arner, E.S.J. ; Östman, A.
Selective activation of oxidized PTP1B by the thioredoxin system modulates PDGF-β receptor tyrosine kinase signaling.Zimprich, A.
Impact of acute and chronic restraint stress on behaviour and neuronal morphology in genetically modified mouse models.Simon, M.M. ; Greenaway, S. ; White, J.K. ; Fuchs, H. ; Gailus-Durner, V. ; Sorg, T. ; Wong, K. ; Bedu, E. ; Cartwright, E.J. ; Dacquin, R. ; Estabel, J. ; Graw, J. ; Ingham, N.J. ; Jackson, I.J. ; Lengeling, A. ; Mandillo, S. ; Marvel, J. ; Meziane, H. ; Preitner, F. ; Puk, O. ; Roux, M. ; Adams, D.J. ; Atkins, S. ; Ayadi, A. ; Becker, L. ; Blake, A. ; Brooker, D. ; Cater, H. ; Champy, M.-F. ; Combe, R. ; Danecek, P. ; di Fenza, A. ; Gates, H. ; Gerdin, A.-K. ; Golini, E. ; Hancock, J.M. ; Hans, W. ; Hölter, S.M. ; Hough, T. ; Jurdic, P. ; Keane, T.M ; Morgan, H. ; Müller, W. ; Neff, F. ; Nicholson, G. ; Pasche, B. ; Roberson, L.-A. ; Rozman, J. ; Sanderson, M. ; Santos, L. ; Selloum, M. ; Shannon, C. ; Southwell, A. ; Tocchini-Valentini, G.P. ; Vancollie, V.E. ; Wells, S. ; Westerberg, H. ; Wurst, W. ; Zi, M. ; Yalcin, B. ; Ramirez-Solis, R. ; Steel, K.P. ; Mallon, A.-M. ; Hrabě de Angelis, M. ; Herault, Y. ; Brown, S.D.M.
A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains.Puk, O. ; Hrabě de Angelis, M. ; Graw, J.
Lens density tracking in mice by Scheimpflug imaging.Ninkovic, J. ; Steiner-Mezzadri, A. ; Jawerka, M. ; Akinci, U. ; Masserdotti, G. ; Petricca, S. ; Fischer, J. ; von Holst, A. ; Beckers, J. ; Lie, D.C. ; Petrik, D. ; Miller, E. ; Tang, J. ; Wu, J. ; Lefebvre, V. ; Demmers, J. ; Eisch, A. ; Metzger, D. ; Crabtree, G. ; Irmler, M. ; Poot, R. ; Götz, M.
The BAF complex interacts with Pax6 in adult neural progenitors to establish a neurogenic cross-regulatory transcriptional network.Hock, S. ; Ng, Y.K. ; Hasenauer, J. ; Wittmann, D.M. ; Lutter, D. ; Trümbach, D. ; Wurst, W. ; Prakash, N. ; Theis, F.J.
Sharpening of expression domains induced by transcription and microRNA regulation within a spatio-temporal model of mid-hindbrain boundary formation.Kratzer, S. ; Mattusch, C. ; Metzger, M.W. ; Dedic, N. ; Noll-Hussong, M. ; Kafitz, K.W. ; Eder, M. ; Deussing, J.M. ; Holsboer, F. ; Kochs, E. ; Rammes, G.
Activation of CRH receptor type 1 expressed on glutamatergic neurons increases excitability of CA1 pyramidal neurons by the modulation of voltage-gated ion channels.Patterson, A.D. ; Carlson, B.A. ; Li, F. ; Bonzo, J.A. ; Yoo, M.H. ; Krausz, K.W. ; Conrad, M. ; Chen, C. ; Gonzalez, F.J. ; Hatfield, D.L.
Disruption of thioredoxin reductase 1 protects mice from acute acetaminophen-induced hepatotoxicity through enhanced NRF2 activity.Neff, F. ; Flores-Dominguez, D. ; Ryan, D.P. ; Horsch, M. ; Schröder, S. ; Adler, T. ; Afonso, L.C. ; Aguilar-Pimentel, J.A. ; Becker, L. ; Garrett, L. ; Hans, W. ; Hettich, M.M. ; Holtmeier, R. ; Hölter, S.M. ; Moreth, K. ; Prehn, C. ; Puk, O. ; Rácz, I. ; Rathkolb, B. ; Rozman, J. ; Naton, B. ; Ordemann, R. ; Adamski, J. ; Beckers, J. ; Bekeredjian, R. ; Busch, D.H. ; Ehninger, G. ; Graw, J. ; Höfler, H. ; Klingenspor, M. ; Klopstock, T. ; Ollert, M. ; Stypmann, J. ; Wolf, E. ; Wurst, W. ; Zimmer, A. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Ehniger, D.
Rapamycin extends murine lifespan but has limited effects on aging.Merz, K. ; Lie, D.C.
Evidence that doublecortin is dispensable for the development of adult born neurons in mice.Møller, T.C. ; Wirth, V.F. ; Roberts, N.I. ; Bender, J. ; Bach, A. ; Jacky, B.P.S. ; Strømgaard, K. ; Deussing, J.M. ; Schwartz, T.W. ; Martinez, K.L.
PDZ domain-mediated interactions of G protein-coupled receptors with postsynaptic density protein 95: Quantitative characterization of interactions.Cioni, J.-M. ; Telley, L. ; Saywell, V. ; Cadilhac, C. ; Jourdan, C. ; Huber, A.B. ; Huang, J.Z. ; Jahannault-Talignani, C. ; Ango, F.
SEMA3A signaling controls layer-specific interneuron branching in the cerebellum.Stribl, C.B.
Effects of a human ALS causative point mutation expressed in mouse - generation and analysis.Doberauer, K.
Sox11 as a regulator of neuronal maturation & integration in the adult hippocampus.Ebert, B.
The effect of mitochondrial dysfunction on astrocytes and radial glia like stem cells in the adult hippocampus.Kerner, A.-L.
Analysis of the function of the polarity factors aPKCi and MPP5 in migration and differentiation of granule cells in the cerebellum of Danio rerio.Wortmann, M. ; Schneider, M. ; Pircher, J. ; Hellfritsch, J. ; Aichler, M. ; Vegi, N. ; Koelle, P. ; Kuhlencordt, P. ; Walch, A.K. ; Pohl, U. ; Bornkamm, G.W. ; Conrad, M. ; Beck, H.
Combined deficiency in glutathione peroxidase 4 and vitamin E causes multi-organ thrombus formation and early death in mice.Bannik, K. ; Rössler, U. ; Faus-Kessler, T. ; Gomolka, M. ; Hornhardt, S. ; Dalke, C. ; Klymenko, O. ; Rosemann, M. ; Trott, K.-R. ; Atkinson, M.J. ; Kulka, U. ; Graw, J.
Are mouse lens epithelial cells more sensitive to γ-irradiation than lymphocytes?Renner, S. ; Braun-Reichhart, C. ; Blutke, A. ; Herbach, N. ; Emrich, D. ; Streckel, E. ; Wünsch, A. ; Kessler, B. ; Kurome, M. ; Bahr, A. ; Klymiuk, N. ; Krebs, S. ; Puk, O. ; Nagashima, H. ; Graw, J. ; Blum, H. ; Wanke, R. ; Wolf, E.
Permanent neonatal diabetes in INSC94Y transgenic pigs.Giesert, F. ; Hofmann, A. ; Bürger, A. ; Zerle, J. ; Kloos, K. ; Hafen, U. ; Ernst, L. ; Zhang, J. ; Vogt Weisenhorn, D.M. ; Wurst, W.
Expression analysis of lrrk1, lrrk2 and lrrk2 splice variants in mice.Sengupta, A. ; Lichti, U.F. ; Carlson, B.A. ; Cataisson, C. ; Ryscavage, A.O. ; Mikulec, C. ; Conrad, M. ; Fischer, S.M. ; Hatfield, D.L. ; Yuspa, S.H.
Targeted disruption of glutathione peroxidase 4 in mouse skin epithelial cells impairs postnatal hair follicle morphogenesis that is partially rescued through inhibition of COX-2.Puk, O. ; Hrabě de Angelis, M. ; Graw, J.
Longitudinal fundus and retinal studies with SD-OCT: A comparison of five mouse inbred strains.Wang, X.D. ; Su, Y.A. ; Wagner, K.V. ; Avrabos, C. ; Scharf, S.H. ; Hartmann, J. ; Wolf, M. ; Liebl, C. ; Kühne, C. ; Wurst, W. ; Holsboer, F. ; Eder, M. ; Deussing, J.M. ; Müller, M.B. ; Schmidt, M.V.
Nectin-3 links CRHR1 signaling to stress-induced memory deficits and spine loss.Conrad, M. ; Schick, J. ; Friedmann Angeli, J.P.F.
Glutathione and thioredoxin dependent systems in neurodegenerative disease: What can be learned from reverse genetics in mice.Ortiz, O. ; Wurst, W. ; Kühn, R.
Reversible and tissue-specific activation of MAP kinase signaling by tamoxifen in brafV637 ERT2 mice.Bosello-Travain, V. ; Conrad, M. ; Cozza, G. ; Negro, A. ; Quartesan, S. ; Rossetto, M. ; Roveri, A. ; Toppo, S. ; Ursini, F. ; Zaccarin, M. ; Maiorino, M.
Protein disulfide isomerase and glutathione are alternative substrates in the one Cys catalytic cycle of glutathione peroxidase 7.Kugler, J.E. ; Horsch, M. ; Huang, D. ; Furusawa, T. ; Rochman, M. ; Garrett, L. ; Becker, L. ; Bohla, A. ; Hölter, S.M. ; Prehn, C. ; Rathkolb, B. ; Rácz, I. ; Aguilar-Pimentel, J.A. ; Adler, T. ; Adamski, J. ; Beckers, J. ; Busch, D.H. ; Eickelberg, O. ; Klopstock, T. ; Ollert, M. ; Stöger, T. ; Wolf, E. ; Wurst, W. ; Yildirim, A.Ö. ; Zimmer, A. ; Gailus-Durner, V. ; Fuchs, H. ; Hrabě de Angelis, M. ; Garfinkel, B. ; Orly, Y. ; Ovcharenko, I. ; Bustin, M.
High mobility group N proteins modulate the fidelity of the cellular transcriptional profile in a tissue- and variant-specific manner.Puk, O. ; Yan, X. ; Sabrautzki, S. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Graw, J.
Novel small-eye allele in paired box gene 6 (Pax6) is caused by a point mutation in intron 7 and creates a new exon.Müller-Rischart, A.K. ; Pilsl, A. ; Beaudette, P. ; Patra, M. ; Hadian, K. ; Funke, M. ; Peis, R. ; Deinlein, A. ; Schweimer, C. ; Kuhn, P.-H. ; Lichtenthaler, S.F. ; Motori, E. ; Hrelia, S. ; Wurst, W. ; Trümbach, D. ; Langer, T. ; Krappmann, D. ; Dittmar, G. ; Tatzelt, J. ; Winklhofer, K.F.
The E3 ligase Parkin maintains mitochondrial integrity by increasing linear ubiquitination of NEMO.Vogel, K.U. ; Edelmann, S.L. ; Jeltsch, K. ; Bertossi, A. ; Heger, K. ; Heinz, G.A. ; Zöller, J. ; Warth, S.C. ; Höfig, K.P. ; Lohs, C. ; Neff, F. ; Kremmer, E. ; Schick, J. ; Repsilber, D. ; Geerlof, A. ; Blum, H. ; Wurst, W. ; Heikenwälder, M. ; Schmidt-Supprian, M. ; Heissmeyer, V.
Roquin paralogs 1 and 2 redundantly repress the Icos and Ox40 costimulator mRNAs and control follicular helper T cell differentiation.Wefers, B. ; Meyer, M. ; Ortiz, O. ; Hrabě de Angelis, M. ; Hansen, J. ; Wurst, W. ; Kühn, R.
Direct production of mouse disease models by embryo microinjection of TALENs and oligodeoxynucleotides.Kirchner, M. ; Faus-Kessler, T. ; Jakobi, G. ; Leuchner, M. ; Ries, L. ; Scheel, H.-E. ; Suppan, P.
Altitudinal temperature lapse rates in an Alpine valley: Trends and the influence of season and weather patterns.Merkl, C. ; Saalfrank, A. ; Riesen, N. ; Kühn, R. ; Pertek, A. ; Eser, S. ; Hardt, M.S. ; Kind, A. ; Saur, D. ; Wurst, W. ; Iglesias, A. ; Schnieke, A.
Efficient generation of rat induced pluripotent stem cells using a non-viral inducible vector.Wefers, B. ; Meyer, M. ; Hensler, S. ; Panda, S. ; Ortiz, O. ; Wurst, W. ; Kühn, R.
Gene editing in one-cell embryos by zinc-finger and TAL nucleases.Thiele, F. ; Cohrs, C.M. ; Przemeck, G.K.H. ; Wurst, W. ; Fuchs, H. ; Hrabě de Angelis, M.
In vitro analysis of bone phenotypes in Col1a1 and Jagged1 mutant mice using a standardized osteoblast cell culture system.Desbordes, S.C. ; Studer, L.
Adapting human pluripotent stem cells to high-throughput and high-content screening.di Giovannantonio, L.G. ; di Salvio, M. ; Acampora, D. ; Prakash, N. ; Wurst, W. ; Simeone, A.
Otx2 selectively controls the neurogenesis of specific neuronal subtypes of the ventral tegmental area and compensates En1-dependent neuronal loss and MPTP vulnerability.Bolze, F. ; Rink, N. ; Brumm, H. ; Kühn, R. ; Mocek, S. ; Schwarz, A.E. ; Kless, C. ; Biebermann, H. ; Wurst, W. ; Rozman, J. ; Klingenspor, M.
Characterization of the melanocortin-4-receptor nonsense mutation W16X in vitro and in vivo.Liu, C.
Genetic modeling of a neurodegenerative polyglutamine disorder in zebrafish and analysis of polyglutamine aggregate dynamics.Vogl, A.M.
Multiple functions of neddylation in neuronal development.Söllner, H.
Developmental wiring and adaptive plasticity of peripheral sensorimotor circuitry.Wolff, C.J.
Proteinanalyse klinisch relevanter Signalmoleküle aus Formalin-fixierten Tumorgeweben.Peis, R.
Prediction of new regulatory molecular networks in neurodegenerative diseases with the help of bioinformatical methods.Ng, Y.K.
Functions of microRNAs in the developing midbrain-hindbrain of the mouse.Peng, C.
Function of Pitx3 and miRNAs in midbrain dopaminergic neurons.Schwarz, T.J.
Examining new interactors of Notch/RBPJκ signalling in adult neural stem cells.Walser, S.M.
Validation of P2RX7 and TMEM132D as susceptibility genes for depression using genetic mouse models.Giesert, F.
Pathogenic mutation of Lrrk2 - a Mouse Model for pre-motor Parkinson’s disease.Hüttl, R.E.
Molecular mechanisms that govern the establishment of sensory-motor networks.Liu, C.
Genetic modeling of a neurodegenerative polyglutamine disorder in zebrafish and analysis of polyglutamine aggregate dynamics.Schäfer, A.
Aldehyde dehydrogenase 1 A1 is expressed by cancer stem cells and mediates chemoresistance in human glioblastoma.Conrad, M.
Mouse models for Glutathione Peroxidase 4 (GPx4).Kleinhammer, A.
Analysis of tau phosphorylation in transgenic ES and iPS cell-derived neurons.Kühn, R. ; Wurst, W.
Improved recombination efficiency by inhibition of NHEJ DNA repair.Kühn, R.
Protein having nuclease activity, fusion proteins and uses thereof.Lerche, K.
Dissecting the role of CRH and CRH-R1 in Alzheimer´s disease.Doll, S.
Engineering new in vitro models of Alzheimer's disease.Xie, X. ; Mathias, J.R. ; Smith, M.A. ; Walker, S.L. ; Teng, Y. ; Distel, M. ; Köster, R.W. ; Sirotkin, H.I. ; Saxena, M.T. ; Mumm, J.S.
Silencer-delimited transgenesis: NRSE/RE1 sequences promote neural-specific transgene expression in a NRSF/REST-dependent manner.Audouard, E. ; Schakman, O. ; René, F. ; Hüttl, R.E. ; Huber, A.B. ; Loeffler, J.-P. ; Gailly, P. ; Clotman, F.
The onecut transcription factor HNF-6 regulates in motor neurons the formation of the neuromuscular junctions.Mellett, M. ; Atzei, P. ; Horgan, A. ; Hams, E. ; Floß, T. ; Wurst, W. ; Fallon, P.G. ; Moynagh, P.N.
Orphan receptor IL-17RD tunes IL-17A signalling and is required for neutrophilia.Donahue, L. R. ; Hrabě de Angelis, M. ; Hagn, M. ; Franklin, C. ; Lloyd, K.C.K. ; Magnuson, T. ; McKerlie, C. ; Nakagata, N. ; Obata, Y. ; Read, S. ; Wurst, W. ; Hörlein, A. ; Davisson, M. T.
Centralized mouse repositories.Delogu, A. ; Sellers, K. ; Zagoraiou, L. ; Bocianowska-Zbrog, A. ; Mandal, S. ; Guimera, J. ; Rubenstein, J.L.R. ; Sugden, D. ; Jessell, T. ; Lumsden, A.
Subcortical visual shell nuclei targeted by ipRGCs develop from a Sox14+-GABAergic progenitor and require Sox14 to regulate daily activity rhythms.Fuchs, H. ; Gailus-Durner, V. ; Neschen, S. ; Adler, T. ; Afonso, L.C. ; Aguilar-Pimentel, J.A. ; Becker, L. ; Bohla, A. ; Calzada-Wack, J. ; Cohrs, C.M. ; Dewert, A. ; Fridrich, B. ; Garrett, L. ; Glasl, L. ; Götz, A. ; Hans, W. ; Hölter, S.M. ; Horsch, M. ; Hurt, A. ; Janas, E. ; Janik, D. ; Kahle-Stephan, M. ; Kistler, M. ; Klein-Rodewald, T. ; Lengger, C. ; Ludwig, T. ; Maier, H. ; Marschall, S. ; Micklich, K. ; Möller, G. ; Naton, B. ; Prehn, C. ; Puk, O. ; Rácz, I. ; Räß, M. ; Rathkolb, B. ; Rozman, J. ; Scheerer, M. ; Schiller, E. ; Schrewe, A. ; Steinkamp, R. ; Stoeger, C. ; Sun, M. ; Szymczak, W. ; Treise, I. ; Vargas Panesso, I.L. ; Vernaleken, A. ; Willershäuser, M. ; Zimprich, A. ; Zeh, R.M. ; Adamski, J. ; Beckers, J. ; Bekeredjian, R. ; Busch, D.H. ; Eickelberg, O. ; Favor, J. ; Graw, J. ; Höfler, H. ; Hoeschen, C. ; Katus, H.A. ; Klingenspor, M. ; Klopstock, T. ; Neff, F. ; Ollert, M. ; Schulz, H. ; Stöger, T. ; Wolf, E. ; Wurst, W. ; Yildirim, A.Ö. ; Zimmer, A. ; Hrabě de Angelis, M.
Innovations in phenotyping of mouse models in the German Mouse Clinic.Klymiuk, I. ; Kenner, L. ; Adler, T. ; Busch, D.H. ; Boersma, A. ; Irmler, M. ; Fridrich, B. ; Gailus-Durner, V. ; Fuchs, H. ; Leitner, N. ; Müller, M. ; Kühn, R. ; Schlederer, M. ; Treise, I. ; Hrabě de Angelis, M. ; Beckers, J.
In vivo functional requirement of the mouse Ifitm1 gene for germ cell development, interferon mediated immune response and somitogenesis.Niv, F. ; Keiner, S. ; Krishna-K, . ; Witte, O.W. ; Lie, D.C. ; Redecker, C.
Aberrant neurogenesis after stroke: A retroviral cell labeling study.Bradley, A. ; Anastassiadis, K. ; Ayadi, A. ; Battey, J.F. ; Bell, C. ; Birling, M.-C. ; Bottomley, J. ; Brown, S.D. ; Bürger, A. ; Bult, C.J. ; Bushell, W. ; Collins, F.S. ; Desaintes, C. ; Doe, B. ; Economides, A. ; Eppig, J.T. ; Finnell, R.H. ; Fletcher, C. ; Fray, M. ; Frendewey, D. ; Friedel, R.H. ; Grosveld, F.G. ; Hansen, J. ; Herault, Y. ; Hicks, G. ; Hörlein, A. ; Houghton, R. ; Hrabě de Angelis, M. ; Huylebroeck, D. ; Iyer, V. ; de Jong, P.J. ; Kadin, J.A. ; Kaloff, C. ; Kennedy, K. ; Koutsourakis, M. ; Lloyd, K.C.K. ; Marschall, S. ; Mason, J. ; McKerlie, C. ; McLeod, M.P. ; von Melchner, H. ; Moore, M. ; Mujica, A.O. ; Nagy, A. ; Nefedov, M. ; Nutter, L.M. ; Pavlovic, G. ; Peterson, J.L. ; Pollock, J. ; Ramirez-Solis, R. ; Rancourt, D.E. ; Raspa, M. ; Remacle, J.E. ; Ringwald, M. ; Rosen, B. ; Rosenthal, N. ; Rossant, J. ; Ruiz Noppinger, P. ; Ryder, E. ; Schick, J. ; Schnütgen, F. ; Schofield, P. ; Seisenberger, C. ; Selloum, M. ; Simpson, E.M. ; Skarnes, W.C. ; Smedley, D. ; Stanford, W.L. ; Francis Stewart, A. ; Stone, K. ; Swan, K. ; Tadepally, H. ; Teboul, L. ; Tocchini-Valentini, G.P. ; Valenzuela, D. ; West, A.P. ; Yamamura, K. ; Yoshinaga, Y. ; Wurst, W.
The mammalian gene function resource: The International Knockout Mouse Consortium.Karow, M. ; Sánchez, R. ; Schichor, C. ; Masserdotti, G. ; Ortega, F. ; Heinrich, C. ; Gascón, S. ; Khan, M.A. ; Lie, D.C. ; Dellavalle, A. ; Cossu, G. ; Goldbrunner, R. ; Götz, M. ; Berninger, B.
Reprogramming of pericyte-derived cells of the adult human brain into induced neuronal cells.Roy, A. ; Francius, C. ; Rousso, D.L. ; Seuntjens, E. ; Debruyn, J. ; Luxenhofer, G. ; Huber, A.B. ; Huylebroeck, D. ; Novitch, B.G. ; Clotman, F.
Onecut transcription factors act upstream of Isl1 to regulate spinal motoneuron diversification.Lehmann, F.M. ; Feicht, S. ; Helm, F. ; Maurberger, A. ; Ladinig, C. ; Zimber-Strobl, U. ; Kühn, R. ; Mautner, J. ; Gerbitz, A. ; Bornkamm, G.W.
Humanized c-Myc mouse.Peng, C. ; Li, N. ; Ng, Y.K. ; Zhang, J. ; Meier, F. ; Theis, F.J. ; Merkenschlager, M. ; Chen, W. ; Wurst, W. ; Prakash, N.
A unilateral negative feedback loop between miR-200 microRNAs and Sox2/E2F3 controls neural progenitor cell-cycle exit and differentiation.Augustin, R. ; Endres, K. ; Reinhardt, S. ; Kuhn, P.H. ; Lichtenthaler, S.F. ; Hansen, J. ; Wurst, W. ; Trümbach, D.
Computational identification and experimental validation of microRNAs binding to the Alzheimer-related gene ADAM10.Kühne, C. ; Puk, O. ; Graw, J. ; Hrabě de Angelis, M. ; Schütz, G. ; Wurst, W. ; Deussing, J.M.
Visualizing corticotropin-releasing hormone receptor type 1 expression and neuronal connectivities in the mouse using a novel multifunctional allele.Yeritsyan, N. ; Lehmann, K. ; Puk, O. ; Graw, J. ; Löwel, S.
Visual capabilities and cortical maps in BALB/c mice.Steinhart, M.R. ; Cone, F.E. ; Nguyen, C. ; Nguyen, T.D. ; Pease, M.E. ; Puk, O. ; Graw, J. ; Oglesby, E.N. ; Quigley, H.A.
Mice with an induced mutation in collagen 8A2 develop larger eyes and are resistant to retinal ganglion cell damage in an experimental glaucoma model.Hüttemann, M. ; Lee, I. ; Gao, X. ; Pecina, P. ; Pecinova, A. ; Liu, J. ; Aras, S. ; Sommer, N. ; Sanderson, T.H. ; Tost, M. ; Neff, F. ; Aguilar-Pimentel, J.A. ; Becker, L. ; Naton, B. ; Rathkolb, B. ; Rozman, J. ; Favor, J. ; Hans, W. ; Prehn, C. ; Puk, O. ; Schrewe, A. ; Sun, M. ; Höfler, H. ; Adamski, J. ; Bekeredjian, R. ; Graw, J. ; Adler, T. ; Busch, D.H. ; Klingenspor, M. ; Klopstock, T. ; Ollert, M. ; Wolf, E. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Weissmann, N. ; Doan, J.W. ; Bassett, D.J. ; Grossman, L.I.
Cytochrome c oxidase subunit 4 isoform 2-knockout mice show reduced enzyme activity, airway hyporeactivity, and lung pathology.Fuchs, H. ; Sabrautzki, S. ; Seedorf, H. ; Rathkolb, B. ; Rozman, J. ; Hans, W. ; Schneider, R. ; Klaften, M. ; Hölter, S.M. ; Becker, L. ; Klempt, M. ; Elvert, R. ; Wurst, W. ; Klopstock, T. ; Klingenspor, M. ; Wolf, E. ; Gailus-Durner, V. ; Hrabě de Angelis, M.
Does enamelin have pleiotropic effects on organs other than the teeth? Lessons from a phenotyping screen of two enamelin-mutant mouse lines.Hüttl, R.E. ; Haehl, T. ; Huber, A.B.
Fasciculation and guidance of spinal motor axons in the absence of FGFR2 signaling.Breu, J. ; Touma, C. ; Hölter, S.M. ; Knapman, A. ; Wurst, W. ; Deussing, J.M.
Urocortin 2 modulates aspects of social behaviour in mice.Graf, C. ; Kuehne, C. ; Panhuysen, M. ; Puetz, B. ; Weber, P. ; Holsboer, F. ; Wurst, W. ; Deussing, J.M.
Corticotropin-releasing hormone regulates common target genes with divergent functions in corticotrope and neuronal cells.Fuchs, H. ; Neschen, S. ; Rozman, J. ; Rathkolb, B. ; Wagner, S. ; Adler, T. ; Alfonso, L. ; Aguilar-Pimentel, J.A. ; Becker, L. ; Bohla, A. ; Calzada-Wack, J. ; Cohrs, C.M. ; Frankó, A. ; Garrett, L. ; Glasl, L. ; Götz, A. ; Hagn, M. ; Hans, W. ; Hölter, S.M. ; Horsch, M. ; Kahle-Stephan, M. ; Kistler, M. ; Klein-Rodewald, T. ; Lengger, C. ; Ludwig, T. ; Maier, H. ; Marschall, S. ; Micklich, K. ; Möller, G. ; Naton, B. ; Neff, F. ; Prehn, C. ; Puk, O. ; Rácz, I. ; Räß, M. ; Scheerer, M. ; Schiller, E. ; Schöfer, F.H. ; Schrewe, A. ; Steinkamp, R. ; Stoeger, C. ; Treise, I. ; Willershäuser, M. ; Zimprich, A. ; Zeh, R.M. ; Adamski, J. ; Beckers, J. ; Bekeredjian, R. ; Busch, D.H. ; Favor, J. ; Graw, J. ; Katus, H.A. ; Klopstock, T. ; Ollert, M. ; Schulz, H. ; Stöger, T. ; Wurst, W. ; Yildirim, A.Ö. ; Zimmer, A. ; Wolf, E. ; Klingenspor, M. ; Gailus-Durner, V. ; Hrabě de Angelis, M.
Mouse genetics and metabolic mouse phenotyping.Waltereit, R. ; Leimer, U. ; von Bohlen und Halbach, O. ; Panke, J. ; Hölter, S.M. ; Garrett, L. ; Wittig, K. ; Schneider, M. ; Schmitt, C. ; Calzada-Wack, J. ; Neff, F. ; Becker, L. ; Prehn, C. ; Kutscherjawy, S. ; Endris, V. ; Bacon, C. ; Fuchs, H. ; Gailus-Durner, V. ; Berger, S. ; Schönig, K. ; Adamski, J. ; Klopstock, T. ; Esposito, I. ; Wurst, W. ; Hrabě de Angelis, M. ; Rappold, G. ; Wieland, T. ; Bartsch, D.
Srgap3-/- mice present a neurodevelopmental disorder with schizophrenia-related intermediate phenotypes.Irmler, M. ; Gentier, R.J. ; Dennissen, F.J. ; Schulz, H. ; Bolle, I. ; Hölter, S.M. ; Kallnik, M. ; Cheng, J.J. ; Klingenspor, M. ; Rozman, J. ; Ehrhardt, N. ; Hermes, D.J. ; Gailus-Durner, V. ; Fuchs, H. ; Hrabě de Angelis, M. ; Meyer, H.E. ; Hopkins, D.A. ; van Leeuwen, F.W. ; Beckers, J.
Long-term proteasomal inhibition in transgenic mice by UBB+1 expression results in dysfunction of central respiration control reminiscent of brainstem neuropathology in Alzheimer patients.Thiele, F. ; Cohrs, C.M. ; Flor, A. ; Lisse, T.S. ; Przemeck, G.K.H. ; Horsch, M. ; Schrewe, A. ; Gailus-Durner, V. ; Ivandic, B. ; Katus, H.A. ; Wurst, W. ; Reisenberg, C. ; Chaney, H. ; Fuchs, H. ; Hans, W. ; Beckers, J. ; Marini, J.C. ; Hrabě de Angelis, M.
Cardiopulmonary dysfunction in the osteogenesis imperfecta mouse model Aga2 and human patients are caused by bone-independent mechanisms.Garrett, L. ; Lie, D.C. ; Hrabě de Angelis, M. ; Wurst, W. ; Hölter, S.M.
Voluntary wheel running in mice increases the rate of neurogenesis without affecting anxiety-related behaviour in single tests.Pihlajamäki, J. ; Lerin, C. ; Kaminska, D. ; Venesmaa, S. ; Itkonen, P. ; Boes, T. ; Floß, T. ; Schroeder, J. ; Dearie, F. ; Crunkhorn, S. ; Burak, F. ; Jimenez-Chillaron, J.C. ; Kuulasmaa, T. ; Miettinen, P. ; Park, P.J. ; Nasser, I. ; Zhao, Z.W. ; Zhang, Z.Y. ; Xu, Y. ; Wurst, W. ; Ren, H.M. ; Morris, A.J. ; Stamm, S. ; Goldfine, A.B. ; Laakso, M. ; Patti, M.E.
SFRS10-A splicing factor gene reduced in human obesity? Response.Rehklau, K. ; Gurniak, C.B. ; Conrad, M. ; Friauf, E. ; Ott, M. ; Rust, M.B.
ADF/cofilin proteins translocate to mitochondria during apoptosis but are not generally required for cell death signaling.Staropoli, J.F. ; Haliw, L. ; Biswas, S. ; Garrett, L. ; Hölter, S.M. ; Becker, L. ; Skosyrski, S. ; Da Silva-Buttkus, P. ; Calzada-Wack, J. ; Neff, F. ; Rathkolb, B. ; Rozman, J. ; Schrewe, A. ; Adler, T. ; Puk, O. ; Sun, M. ; Favor, J. ; Rácz, I. ; Bekeredjian, R. ; Busch, D.H. ; Graw, J. ; Klingenspor, M. ; Klopstock, T. ; Wolf, E. ; Wurst, W. ; Zimmer, A. ; Lopez, E. ; Harati, H. ; Hill, E. ; Krause, D.S. ; Guide, J. ; Dragileva, E. ; Gale, E. ; Wheeler, V.C. ; Boustany, R.M. ; Brown, D.E. ; Breton, S. ; Ruether, K. ; Gailus-Durner, V. ; Fuchs, H. ; Hrabě de Angelis, M. ; Cotman, S.L.
Large-scale phenotyping of an accurate genetic mouse model of JNCL identifies novel early pathology outside the central nervous system.Noblanc, A. ; Peltier, M. ; Damon-Soubeyrand, C. ; Kerchkove, N. ; Chabory, E. ; Vernet, P. ; Saez, F. ; Cadet, R. ; Janny, L. ; Pons-Rejraji, H. ; Conrad, M. ; Drevet, J.R. ; Kocer, A.
Epididymis response partly compensates for spermatozoa oxidative defects in snGPx4 and GPx5 double mutant mice.Schwarz, T.J. ; Ebert, B. ; Lie, D.C.
Stem cell maintenance in the adult mammalian hippocampus: A matter of signal integration?Coolen, M. ; Thieffry, D. ; Drivenes, O. ; Becker, T.S. ; Bally-Cuif, L.
MiR-9 controls the timing of neurogenesis through the direct inhibition of antagonistic factors.Menke, A. ; Knauer-Arloth, J. ; Pütz, B. ; Weber, P. ; Klengel, T. ; Mehta, D. ; Gonik, M. ; Rex-Haffner, M. ; Rubel, J. ; Uhr, M. ; Lucae, S. ; Deussing, J.M. ; Müller-Myhsok, B. ; Holsboer, F. ; Binder, E.B.
Dexamethasone stimulated gene expression in peripheral blood is a sensitive marker for glucocorticoid receptor resistance in depressed patients.Meyer, M. ; Ortiz, O. ; Hrabě de Angelis, M. ; Wurst, W. ; Kühn, R.
Modeling disease mutations by gene targeting in one-cell mouse embryos.Wefers, B. ; Hitz, C. ; Hölter, S.M. ; Trümbach, D. ; Hansen, J. ; Weber, P. ; Pütz, B. ; Deussing, J.M. ; Hrabě de Angelis, M. ; Roenneberg, T. ; Zheng, F. ; Alzheimer, C. ; Silva, A. ; Wurst, W. ; Kühn, R.
MAPK signaling determines anxiety in the juvenile mouse brain but depression-like behavior in adults.Agoston, Z. ; Li, N. ; Haslinger, A. ; Wizenmann, A. ; Schulte, D.
Genetic and physical interaction of Meis2, Pax3 and Pax7 during dorsal midbrain development.Yin, R. ; Messner, B. ; Faus-Kessler, T. ; Hoffmann, T. ; Schwab, W. ; Hajirezaei, M.-R. ; von Saint Paul, V. ; Heller, W. ; Schäffner, A.
Feedback inhibition of the general phenylpropanoid and flavonol biosynthetic pathways upon a compromised flavonol-3-O-glycosylation.Wang, X.D. ; Labermaier, C. ; Holsboer, F. ; Wurst, W. ; Deussing, J.M. ; Müller, M.B. ; Schmidt, M.V.
Early-life stress-induced anxiety-related behavior in adult mice partially requires forebrain corticotropin-releasing hormone receptor 1.Meixner, A.
Leucine-rich repeat kinase 2 (Lrrk2): Functional characterization and interactome analysis of a protein kinase associated with Parkinson’s disease.Azimzadeh, O. ; Scherthan, H. ; Yentrapalli, R. ; Barjaktarovic, Z. ; Ueffing, M. ; Conrad, M. ; Neff, F. ; Calzada-Wack, J. ; Aubele, M. ; Buske, C. ; Atkinson, M.J. ; Hauck, S.M. ; Tapio, S.
Label-free protein profiling of formalin-fixed paraffin-embedded (FFPE) heart tissue reveals immediate mitochondrial impairment after ionising radiation.Roshan, M. ; Kabekkodu, S.P. ; Vijaya, P.H. ; Manjunath, K. ; Graw, J. ; Gopinath, P.M. ; Satyamoorthy, K.
Analysis of mitochondrial DNA variations in Indian patients with congenital cataract.Mu, L. ; Berti, L. ; Masserdotti, G. ; Covic, M. ; Michaelidis, T.M. ; Doberauer, K. ; Merz, K. ; Rehfeld, F. ; Haslinger, A. ; Wegner, M. ; Sock, E. ; Lefebvre, V. ; Couillard-Despres, S. ; Aigner, L. ; Berninger, B. ; Lie, D.C.
SoxC transcription factors are required for neuronal differentiation in adult hippocampal neurogenesis.Glasl, L. ; Kloos, K. ; Giesert, F. ; Roethig, A. ; di Benedetto, B. ; Kühn, R. ; Zhang, J. ; Hafen, U. ; Zerle, J. ; Hofmann, A. ; Hrabě de Angelis, M. ; Winklhofer, K.F. ; Hölter, S.M. ; Vogt Weisenhorn, D.M. ; Wurst, W.
Pink1-deficiency in mice impairs gait, olfaction and serotonergic innervation of the olfactory bulb.Olszewski, P.K. ; Rozman, J. ; Jacobsson, J.A. ; Rathkolb, B. ; Strömberg, S. ; Hans, W. ; Klockars, A. ; Alsiö, J. ; Risérus, U. ; Becker, L. ; Hölter, S.M. ; Elvert, R. ; Ehrhardt, N. ; Gailus-Durner, V. ; Fuchs, H. ; Fredriksson, R. ; Wolf, E. ; Klopstock, T. ; Wurst, W. ; Levine, A.S. ; Marcus, C. ; Hrabě de Angelis, M. ; Klingenspor, M. ; Schiöth, H.B. ; Kilimann, M.W.
Neurobeachin, a regulator of synaptic protein targeting, is associated with body fat mass and feeding behavior in mice and body-mass index in humans.Aslam, M. ; Ahmad, N. ; Srivastava, R. ; Hemmer, B.
TNF-alpha induced NFκB signaling and p65 (RelA) overexpression repress Cldn5 promoter in mouse brain endothelial cells.Walker, S.L. ; Ariga, J. ; Mathias, J.R. ; Coothankandaswamy, V. ; Xie, X. ; Distel, M. ; Köster, R.W. ; Parsons, M.J. ; Bhalla, K.N. ; Saxena, M.T. ; Mumm, J.S.
Automated reporter quantification in vivo: High-throughput screening method for reporter-based assays in zebrafish.Molander, A. ; Vengeliene, V. ; Heilig, M. ; Wurst, W. ; Deussing, J.M. ; Spanagel, R.
Brain-specific inactivation of the Crhr1 gene inhibits post-dependent and stress-induced alcohol intake, but does not affect relapse-like drinking.Oberoi, T.K. ; Dogan, T. ; Hocking, J.C. ; Scholz, R.P. ; Mooz, J. ; Anderson, C.L. ; Karreman, C. ; Meyer zu Heringdorf, D. ; Schmidt, G. ; Ruonala, M. ; Namikawa, K. ; Harms, G.S. ; Carpy, A. ; Macek, B. ; Köster, R.W. ; Rajalingam, K.
IAPs regulate the plasticity of cell migration by directly targeting Rac1 for degradation.Dedic, N. ; Touma, C. ; Romanowski, C.P. ; Schieven, M. ; Kühne, C. ; Ableitner, M. ; Lu, A. ; Holsboer, F. ; Wurst, W. ; Kimura, M. ; Deussing, J.M.
Assessing behavioural effects of chronic HPA axis activation using conditional CRH-overexpressing mice.Thoeringer, C.K. ; Henes, K. ; Eder, M. ; Dahlhoff, M. ; Wurst, W. ; Holsboer, F. ; Deussing, J.M. ; Moosmang, S. ; Wotjak, C.T.
Consolidation of remote fear memories involves corticotropin-releasing hormone (CRH) receptor type 1-mediated enhancement of AMPA receptor GluR1 signaling in the dentate gyrus.di Benedetto, B. ; Kühn, R. ; Nothdurfter, C. ; Rein, T. ; Wurst, W. ; Rupprecht, R.
N-desalkylquetiapine activates ERK1/2 to induce GDNF release in C6 glioma cells: A putative cellular mechanism for quetiapine as antidepressant.Puglisi, R. ; Maccari, I. ; Pipolo, S. ; Conrad, M. ; Mangia, F. ; Boitani, C.
The nuclear form of Glutathione Peroxidase 4 is associated with sperm nuclear matrix and is required for proper paternal chromatin decondensation at fertilization.Conrad, M. ; Sato, H.
The oxidative stress-inducible cystine/glutamate antiporter, system xc-: Cystine supplier and beyond.Graw, J. ; Puk, O. ; Weber, S. ; Wagner, S. ; Klaften, M. ; Thiele, F. ; Fuchs, H. ; Hrabě de Angelis, M.
Optic nerve phenotypes.Hämmerle, B. ; Ulin, E. ; Guimera, J. ; Becker, W. ; Guillemot, F. ; Tejedor, F.J.
Transient expression of Mnb/Dyrk1a couples cell cycle exit and differentiation of neuronal precursors by inducing p27KIP1 expression and suppressing NOTCH signaling.Pombero, A. ; Bueno, C. ; Saglietti, L. ; Rodenas, M. ; Guimera, J. ; Bulfone, A. ; Martinez, S.
Pallial origin of basal forebrain cholinergic neurons in the nucleus basalis of Meynert and horizontal limb of the diagonal band nucleus.Kühn, R. ; Vogt Weisenhorn, D.M. ; Wurst, W.
Genetic models of Parkinson's disease.Hölter, S.M. ; Glasl, L.
High-troughput mouse phenotyping.von Saint Paul, V. ; Zhang, W. ; Kanawati, B. ; Geist, B. ; Faus-Kessler, T. ; Schmitt-Kopplin, P. ; Schäffner, A.
The Arabidopsis glucosyltransferase UGT76B1 conjugates isoleucic acid and modulates plant defense and senescence.Jakubcakova, V. ; Flachskamm, C. ; Deussing, J.M. ; Kimura, M.
Deficiency of corticotropin-releasing hormone type-2 receptor alters sleep responses to bacterial lipopolysaccharide in mice.Senghaas, N.
Regulation, biochemistry and functional analysis of the conserved Lunapark protein in central nervous system development.Bolze, F.
Funktionelle Charakterisierung der humanen Melanocortin-4-Rezeptor Punktmutationen W16X und V103I.Maier, V.
Characterization of Semaphorin 4C and Semaphorin 4G as candidate ligands of Plexin-B2.Wefers, B.
The role of ERK/MAPK signalling in emotional behaviour – studies on Braf knockout and gain-of-function mutant mice.Chertoff, M. ; di Paolo, N. ; Schoeneberg, A. ; Depino, A. ; Ferrari, C. ; Wurst, W. ; Pfizenmaier, K. ; Eisel, U. ; Pitossi, F.
Neuroprotective and neurodegenerative effects of the chronic expression of tumor necrosis factor α in the nigrostriatal dopaminergic circuit of adult mice.Ahmad, N.
Functional and regulatory network analysis of Pitx3 in aphakia – a mouse model for microphthalmia and Parkinson’s disease.Groß, C.M.
Expression, Regulation und Funktion von Tdp-43 in der Maus.Sun, M.
Crybb2, a new candidate gene for schizophrenia?Hähl, T.
Analysis of candidate genes for motor axon guidance in the spinal cord.Weber, G.
Analysis of effects of Pink1 (PARK6) and Dj-1 (PARK7) deficiency in genetic mouse models of Parkinson's disease.Krummhaar, M.
Regulation of the CRH system in Alzheimer's disease and its influence on neuropathological characteristics using APP over-expressing mouse model.Edelmann, K.
Untersuchung des Insulinwachstumfaktor-Signalweges in der Neurogenese und Gliogenese im adulten und alternden Zebrafisch.Decker, E.
Role of IKK alpha and alternative NFκB pathway in antidepressant mechanism of action.Spengler, D.
Transkriptionelle Mechanismen und biologische Funktion des elterlich geprägten Transkriptionsfaktors Zac1.Zimmermann, C.
Fate mapping of Shh-SBE1 expressing and Wnt-responsive meso-diencephalic dopaminergic neurons.Lange, S.
The role of Fat4 and Dachsous1 in neuronal migration and cell fate determination in the developing mouse cortex.Hörl, G. ; Wagner, A. ; Cole, L.K. ; Malli, R. ; Reicher, H. ; Kotzbeck, P. ; Köfeler, H. ; Höfler, G. ; Frank, S. ; Bogner-Strauss, J.G. ; Sattler, W. ; Vance, D.E. ; Steyrer, E.
Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.Cook, D.R. ; Solski, P.A. ; Bultman, S.J. ; Kauselmann, G. ; Schoor, M. ; Kühn, R. ; Friedman, L.S. ; Cowley, D.O. ; van Dyke, T.A. ; Yeh, J. ; Johnson, L.F. ; Der, C.D.
The Ect2 Rho guanine nucleotide exchange factor is essential for early mouse development and normal cell cytokinesis and migration.Norton, W.H.J. ; Stumpenhorst, K. ; Faus-Kessler, T. ; Folchert, A. ; Rohner, N. ; Harris, M.P. ; Callebert, J. ; Bally-Cuif, L.
Modulation of Fgfr1a signaling in zebrafish reveals a genetic basis for the aggression-boldness syndrome.Refojo, D. ; Schweizer, M. ; Kuehne, C. ; Ehrenberg, S. ; Thoeringer, C. ; Vogl, A.M. ; Dedic, N. ; Schumacher, M. ; von Wolff, G. ; Avrabos, C. ; Touma, C. ; Engblom, D. ; Schütz, G. ; Nave, K.A. ; Eder, M. ; Wotjak, C.T. ; Sillaber, I. ; Holsboer, F. ; Wurst, W. ; Deussing, J.M.
Glutamatergic and dopaminergic neurons mediate anxiogenic and anxiolytic effects of CRHR1.Patchev, A.V. ; Zimprich, A. ; Fischer, D. ; Almeida, O.F.X.
Probing the role of estrogen receptor isoforms in neonatal programming of neuroendocrine and behavioral functions.Wang, X.D. ; Rammes, G. ; Kraev, I. ; Wolf, M. ; Liebl, C. ; Scharf, S.H. ; Rice, C.J. ; Wurst, W. ; Holsboer, F. ; Deussing, J.M. ; Baram, T.Z. ; Stewart, M.G. ; Müller, M.B. ; Schmidt, M.V.
Forebrain CRF1 modulates early-life stress-programmed cognitive deficits.Khan, M.A. ; Lie, D.C.
MicroRNA - a contributor to age-associated neural stem cell dysfunction?Carlson, B.A. ; Yoo, M.H. ; Conrad, M. ; Gladyshev, V.N. ; Hatfield, D.L. ; Park, J.M.
Protein kinase-regulated expression and immune function of thioredoxin reductase 1 in mouse macrophages.Churchill, A. ; Graw, J.
Clinical and experimental advances in congenital and paediatric cataracts.Lee, M.S. ; Theodoropoulou, M. ; Graw, J. ; Roncaroli, F. ; Zatelli, M.C. ; Pellegata, N.S.
Levels of p27 sensitize to dual PI3K/mTOR inhibition.Distel, M. ; Hocking, J.C. ; Köster, R.W.
In vivo cell biology using Gal4-mediated multicolor subcellular labeling in zebrafish.Wullimann, M.F. ; Mueller, T. ; Distel, M. ; Babaryka, A. ; Grothe, B. ; Köster, R.W.
The long adventurous journey of rhombic lip cells in jawed vertebrates: A comparative developmental analysis.Schmidt, M.V. ; Schülke, .J.-P. ; Liebl, C. ; Stiess, M. ; Avrabos, C. ; Bock, J. ; Wochnik, GM. ; Davies, H.A. ; Zimmermann, N. ; Scharf, S.H. ; Trümbach, D. ; Wurst, W. ; Zieglgänsberger, W. ; Turck, C. ; Holsboer, F. ; Stewart, M.G. ; Bradke, F. ; Eder, M. ; Müller, M.B. ; Rein, T.
Tumor suppressor down-regulated in renal cell carcinoma 1 (DRR1) is a stress-induced actin bundling factor that modulates synaptic efficacy and cognition.Hampel, F. ; Ehrenberg, S. ; Hojer, C. ; Draeseke, A. ; Marschall-Schröter, G. ; Kühn, R. ; Mack, B. ; Gires, O. ; Vahl, C.J. ; Schmidt-Supprian, M. ; Strobl, L.J. ; Zimber-Strobl, U.
CD19-independent instruction of murine marginal zone B-cell development by constitutive Notch2 signaling.Graw, J.
Confirmation of single nucleotide mutations.Graw, J. ; Welzl, G. ; Ahmad, N. ; Klopp, N. ; Heier, M. ; Wulff, A. ; Heinrich, J. ; Döring, A. ; Karrasch, S. ; Nowak, D. ; Schulz, S. ; Rathmann, W. ; Illig, T. ; Peters, A. ; Holle, R. ; Meisinger, C. ; Wichmann, H.-E.
The KORA eye study: A population-based study on eye diseases in Southern Germany (KORA F4).Hüttl, R.E. ; Huber, A.B.
Cranial nerve fasciculation and Schwann cell migration are impaired after loss of Npn-1.de Andrés-Aguayo, L. ; Varas, F. ; Kallin, E.M. ; Infante, J.F. ; Wurst, W. ; Floß, T. ; Graf, T.
Musashi 2 is a regulator of the HSC compartment identified by a retroviral insertion screen and knockout mice.Meyer, M. ; Wefers, B. ; Ortiz, O. ; Wurst, W. ; Kühn, R.
Gezielte Manipulation des Genoms mit Zinkfingernukleasen.Piaton, G. ; Aigrot, M.S. ; Williams, A. ; Moyon, S. ; Tepavcevic, V. ; Moutkine, I. ; Gras, J. ; Matho, K.S. ; Schmitt, A. ; Soellner, H. ; Huber, A.B. ; Ravassard, P. ; Lubetzki, C.
Class 3 semaphorins influence oligodendrocyte precursor recruitment and remyelination in adult central nervous system.Hüttl, R.E. ; Soellner, H. ; Bianchi, E. ; Novitch, B.G. ; Huber, A.B.
Npn-1 contributes to axon-axon interactions that differentially control sensory and motor innervation of the limb.Fenzl, T. ; Romanowski, C.P. ; Flachskamm, C. ; Deussing, J.M. ; Kimura, M.
Wake-promoting effects of orexin: Its independent actions against the background of an impaired corticotropine-releasing hormone receptor system.Kleinhammer, A. ; Wurst, W. ; Kühn, R.
Constitutive and conditional RNAi transgenesis in mice.Wang, X.D. ; Chen, Y. ; Wolf, M. ; Wagner, K.V. ; Liebl, C. ; Scharf, S.H. ; Harbich, D. ; Mayer, B. ; Wurst, W. ; Holsboer, F. ; Deussing, J.M. ; Baram, T.Z. ; Müller, M.B. ; Schmidt, M.V.
Forebrain CRHR1 deficiency attenuates chronic stress-induced cognitive deficits and dendritic remodeling.Devigny, C. ; Perez-Balderas, F. ; Hoogeland, B. ; Cuboni, S. ; Wachtel, R. ; Mauch, C.P. ; Webb, K.J. ; Deussing, J.M. ; Hausch, F.
Biomimetic screening of class-B G protein-coupled receptors.Rolyan, H. ; Scheffold, A. ; Heinrich, A. ; Begus-Nahrmann, Y. ; Langkopf, B.H. ; Hölter, S.M. ; Vogt Weisenhorn, D.M. ; Liss, B. ; Wurst, W. ; Lie, D.C. ; Thal, DR. ; Biber, K. ; Rudolph, K.L.
Telomere shortening reduces Alzheimer's disease amyloid pathology in mice.Kollias, G. ; Papadaki, P. ; Apparailly, F. ; Vervoordeldonk, M.J. ; Holmdahl, R. ; Baumans, V. ; Desaintes, C. ; di Santo, J. ; Distler, J. ; Garside, P. ; Hegen, M. ; Huizinga, T.W. ; Jüngel, A. ; Klareskog, L. ; McInnes, I. ; Ragoussis, I. ; Schett, G. ; Hart, B. ; Tak, P.P. ; Toes, R. ; van den Berg, W. ; Wurst, W. ; Gay, S.
Animal models for arthritis: Innovative tools for prevention and treatment.Karalay, O. ; Doberauer, K. ; Vadodaria, K.C. ; Knobloch, M. ; Berti, L. ; Miquelajauregui, A. ; Schwark, M. ; Jagasia, R. ; Taketo, MM. ; Tarabykin, V. ; Lie, D.C. ; Jessberger, S.
Prospero-related homeobox 1 gene (Prox1) is regulated by canonical Wnt signaling and has a stage-specific role in adult hippocampal neurogenesis.Merz, K. ; Herold, S. ; Lie, D.C.
CREB in adult neurogenesis - master and partner in the development of adult-born neurons?Wefers, B. ; Wurst, W. ; Kühn, R.
Design and generation of gene-targeting vectors.Puk, O. ; Möller, G. ; Geerlof, A. ; Krowiorz, K. ; Ahmad, N. ; Wagner, S. ; Adamski, J. ; Hrabě de Angelis, M. ; Graw, J.
The pathologic effect of a novel neomorphic Fgf9Y162C allele is restricted to decreased vision and retarded lens growth.Peng, C. ; Aron, L. ; Klein, R. ; Li, M. ; Wurst, W. ; Prakash, N. ; Le, W.
Pitx3 is a critical mediator of GDNF-induced BDNF expression in nigrostriatal dopaminergic neurons.Maier, V. ; Jolicoeur, C. ; Rayburn, H. ; Takegahara, N. ; Kumanogoh, A. ; Kikutani, H. ; Tessier-Lavigne, M. ; Wurst, W. ; Friedel, R.H.
Semaphorin 4C and 4G are ligands of Plexin-B2 required in cerebellar development.Pihlajamäki, J. ; Lerin, C. ; Itkonen, P. ; Boes, T. ; Floß, T. ; Schroeder, J. ; Dearie, F. ; Crunkhorn, S. ; Burak, F. ; Jimenez-Chillaron, J.C. ; Kuulasmaa, T. ; Miettinen, P. ; Park, P.J. ; Nasser, I. ; Zhao, Z. ; Zhang, Z. ; Xu, Y. ; Wurst, W. ; Ren, H. ; Morris, A.J. ; Stamm, S. ; Goldfine, A.B. ; Laakso, M. ; Patti, M.E.
Expression of the splicing factor gene SFRS10 is reduced in human obesity and contributes to enhanced lipogenesis.Azimzadeh, O. ; Scherthan, H. ; Sarioglu, H. ; Barjaktarovic, Z. ; Conrad, M. ; Vogt, A. ; Calzada-Wack, J. ; Neff, F. ; Aubele, M. ; Buske, C. ; Atkinson, M.J. ; Tapio, S.
Rapid proteomic remodeling of cardiac tissue caused by total body ionizing radiation.Piccoli, G. ; Condliffe, S.B. ; Bauer, M. ; Giesert, F. ; Boldt, K. ; de Astis, S. ; Meixner, A. ; Sarioglu, H. ; Vogt Weisenhorn, D.M. ; Wurst, W. ; Gloeckner, C.J. ; Matteoli, M. ; Sala, C. ; Ueffing, M.
LRRK2 controls synaptic vesicle storage and mobilization within the recycling pool.Gates, H. ; Mallon, A.M. ; Brown, S.D. ; EUMODIC Consortium (Hölter, S.M. ; Glasl, S.)
High-throughput mouse phenotyping.Augustin, R. ; Lichtenthaler, S.F. ; Greeff, M. ; Hansen, J. ; Wurst, W. ; Trümbach, D.
Bioinformatics identification of modules of transcription factor binding sites in Alzheimer's disease-related genes by in silico promoter analysis and microarrays.Chapouton, P. ; Webb, K.J. ; Stigloher, C. ; Alunni, A. ; Adolf, B. ; Hesl, B. ; Topp, S. ; Kremmer, E. ; Bally-Cuif, L.
Expression of hairy/enhancer of split genes in neural progenitors and neurogenesis domains of the adult zebrafish brain.Esperschütz, J. ; Welzl, G. ; Schreiner, K. ; Buegger, F. ; Munch, J.-C. ; Schloter, M.
Incorporation of carbon from decomposing litter of two pioneer plant species into microbial communities of the detritusphere.Webb, K.J. ; Coolen, M. ; Gloeckner, C.J. ; Stigloher, C. ; Bahn, B. ; Topp, S. ; Ueffing, M. ; Bally-Cuif, L.
The Enhancer of split transcription factor Her8a is a novel dimerisation partner for Her3 that controls anterior hindbrain neurogenesis in zebrafish.Esperschütz, J. ; Pérez-de-Mora, A. ; Schreiner, K. ; Welzl, G. ; Buegger, F. ; Zeyer, J. ; Hagedorn, F. ; Munch, J.-C. ; Schloter, M.
Microbial food web dynamics along a soil chronosequence of a glacier forefield.Schnütgen, F. ; Ehrmann, F. ; Poser, I. ; Hubner, N.C. ; Hansen, J. ; Floß, T. ; deVries, I. ; Wurst, W. ; Hyman, A. ; Mann, M. ; von, Melchner, H.
Resources for proteomics in mouse embryonic stem cells.Abe, K. ; Fuchs, H. ; Boersma, A. ; Hans, W. ; Yu, P. ; Kalaydjiev, S. ; Klaften, M. ; Adler, T. ; Calzada-Wack, J. ; Mossbrugger, I. ; Rathkolb, B. ; Rozman, J. ; Prehn, C. ; Maraslioglu, M. ; Kametani, Y. ; Shimada, S. ; Adamski, J. ; Busch, D.H. ; Esposito, I. ; Klingenspor, M. ; Wolf, E. ; Wurst, W. ; Gailus-Durner, V. ; Katan, M. ; Marschall, S. ; Soewarto, D. ; Wagner, S. ; Hrabě de Angelis, M.
A novel N-ethyl-N-nitrosourea-induced mutation in phospholipase Cγ2 causes inflammatory arthritis, metabolic defects, and male infertility in vitro in a murine model.Kotzerke, A. ; Fulle, M. ; Sharma, S. ; Kleineidam, K. ; Welzl, G. ; Lamshöft, M. ; Schloter, M. ; Wilke, B.M.
Alterations in total microbial activity and nitrification rates in soil due to amoxicillin-spiked pig manure.Horsch, M. ; Seeburg, PH. ; Adler, T. ; Aguilar-Pimentel, J.A. ; Becker, L. ; Calzada-Wack, J. ; Garrett, L. ; Götz, A. ; Hans, W. ; Higuchi, M. ; Hölter, S.M. ; Naton, B. ; Prehn, C. ; Puk, O. ; Rácz, I. ; Rathkolb, B. ; Rozman, J. ; Schrewe, A. ; Adamski, J. ; Busch, D.H. ; Esposito, I. ; Graw, J. ; Ivandic, B. ; Klingenspor, M. ; Klopstock, T. ; Mempel, M. ; Ollert, M. ; Schulz, S. ; Wolf, E. ; Wurst, W. ; Zimmer, A. ; Gailus-Durner, V. ; Fuchs, H. ; Hrabě de Angelis, M. ; Beckers, J.
Requirement of the RNA-editing enzyme ADAR2 for normal physiology in mice.Puk, O. ; Ahmad, N. ; Wagner, S. ; Hrabě de Angelis, M. ; Graw, J.
Microphakia and congenital cataract formation in a novel Lim2C51R mutant mouse.Puk, O. ; Ahmad, N. ; Wagner, S. ; Hrabě de Angelis, M. ; Graw, J.
First mutation in the βA2-crystallin encoding gene is associated with small lenses and age-related cataracts.Endlweber, K. ; Krome, K. ; Welzl, G. ; Schäffner, A. ; Scheu, S.
Decomposer animals induce differential expression of defence and auxin-responsive genes in plants.Sibbing, D. ; Pfeufer, A. ; Perisic, T. ; Mannes, A.M. ; Fritz-Wolf, K. ; Unwin, S. ; Sinner, M.F. ; Gieger, C. ; Gloeckner, C.J. ; Wichmann, H.-E. ; Kremmer, E. ; Schäfer, Z. ; Walch, A.K. ; Hinterseer, M. ; Näbauer, M. ; Kääb, S. ; Kastrati, A. ; Schömig, A. ; Meitinger, T. ; Bornkamm, G.W. ; Conrad, M. ; von Beckerath, N.
Mutations in the mitochondrial thioredoxin reductase gene TXNRD2 cause dilated cardiomyopathy.Rothenaigner, I. ; Krecsmarik, M. ; Hayes, J.A. ; Bahn, B. ; Lepier, A. ; Fortin, G. ; Götz, M. ; Jagasia, R. ; Bally-Cuif, L.
Clonal analysis by distinct viral vectors identifies bona fide neural stem cells in the adult zebrafish telencephalon and characterizes their division properties and fate.Noblanc, A. ; Kocer, A. ; Chabory, E. ; Vernet, P. ; Saez, F. ; Cadet, R. ; Conrad, M. ; Drevet, J.R.
Glutathione peroxidases (GPX) at work on epididymal spermatozoa: An example of the dual effect of reactive oxygen species on mammalian male fertilizing ability.Fischer, T. ; Faus-Kessler, T. ; Welzl, G. ; Simeone, A. ; Wurst, W. ; Prakash, N.
Fgf15-mediated control of neurogenic and proneural gene expression regulates dorsal midbrain neurogenesis.Ringwald, M. ; Iyer, V. ; Mason, J.C. ; Stone, K.R. ; Tadepally, H.D. ; Kadin, J.A. ; Bult, C.J. ; Eppig, J.T. ; Oakley, D.J. ; Briois, S. ; Stupka, E. ; Maselli, V. ; Smedley, D. ; Liu, S.Y. ; Hansen, J. ; Baldock, R. ; Hicks, G.G. ; Skarnes, W.C.
The IKMC web portal: A central point of entry to data and resources from the International Knockout Mouse Consortium.Mannes, A.M. ; Seiler, A. ; Bosello, V. ; Maiorino, M. ; Conrad, M.
Cysteine mutant of mammalian GPx4 rescues cell death induced by disruption of the wild type selenoenzyme.Friedel, R.H. ; Wurst, W. ; Wefers, B. ; Kühn, R.
Generating conditional knockout mice.Fuchs, H. ; Gailus-Durner, V. ; Adler, T. ; Aguilar-Pimentel, J.A. ; Becker, L. ; Calzada-Wack, J. ; Da Silva-Buttkus, P. ; Neff, F. ; Götz, A.A. ; Hans, W. ; Hölter, S.M. ; Horsch, M. ; Kastenmüller, G. ; Kemter, E. ; Lengger, C. ; Maier, H. ; Matloka, M. ; Möller, G. ; Naton, B. ; Prehn, C. ; Puk, O. ; Rácz, I. ; Rathkolb, B. ; Römisch-Margl, W. ; Rozman, J. ; Wang-Sattler, R. ; Schrewe, A. ; Stoeger, C. ; Tost, M. ; Adamski, J. ; Aigner, B. ; Beckers, J. ; Behrendt, H. ; Busch, D.H. ; Esposito, I. ; Graw, J. ; Illig, T. ; Ivandic, B. ; Klingenspor, M. ; Klopstock, T. ; Kremmer, E. ; Mempel, M. ; Neschen, S. ; Ollert, M. ; Schulz, S. ; Suhre, K. ; Wolf, E. ; Wurst, W. ; Zimmer, A. ; Hrabě de Angelis, M.
Mouse phenotyping.Massie, A. ; Schallier, A. ; Kim, S.W. ; Fernando, R. ; Kobayashi, S. ; Beck, H. ; de Bundel, D. ; Vermoesen, K. ; Bannai, S. ; Smolders, I. ; Conrad, M. ; Plesnila, N. ; Sato, H. ; Michotte, Y.
Dopaminergic neurons of system xc‾-deficient mice are highly protected against 6-hydroxydopamine-induced toxicity.Bouman, L. ; Schlierf, A. ; Lutz, A.K. ; Shan, J. ; Deinlein, A. ; Kast, J. ; Galehdar, Z. ; Palmisano, V. ; Patenge, N. ; Berg, D. ; Gasser, T. ; Augustin, R. ; Trümbach, D. ; Irrcher, I. ; Park, D.S. ; Wurst, W. ; Kilberg, M.S. ; Tatzelt, J. ; Winklhofer, K.F.
Parkin is transcriptionally regulated by ATF4: Evidence for an interconnection between mitochondrial stress and ER stress.Herold, S. ; Jagasia, R. ; Merz, K. ; Wassmer, K. ; Lie, D.C.
CREB signalling regulates early survival, neuronal gene expression and morphological development in adult subventricular zone neurogenesis.Kleinhammer, A. ; Deussing, J.M. ; Wurst, W. ; Kühn, R.
Conditional RNAi in mice.von Wolff, G. ; Avrabos, C. ; Stepan, J. ; Wurst, W. ; Deussing, J.M. ; Holsboer, F. ; Eder, M.
Voltage-sensitive dye imaging demonstrates an enhancing effect of corticotropin-releasing hormone on neuronal activity propagation through the hippocampal formation.Distel, M. ; Hocking, J.C. ; Köster, R.W.
Imaging the cell biology of neuronal migration in zebrafish.Zhang, J. ; Giesert, F. ; Kloos, K. ; Vogt Weisenhorn, D.M. ; Aigner, L. ; Wurst, W. ; Couillard-Despres, S.
A powerful transgenic tool for fate mapping and functional analysis of newly generated neurons.Chapouton, P. ; Godinho, L.
Neurogenesis.Erben, R.G. ; Zeitz, U. ; Weber, K. ; Stierstorfer, B. ; Wolf, G. ; Schmahl, W. ; Balling, R. ; Quintanilla-Martinez, L.
A non-functioning vitamin D receptor predisposes to leukaemoid reactions in mice.Okuno, T. ; Nakatsuji, Y. ; Moriya, M. ; Takamatsu, H. ; Nojima, S. ; Takegahara, N. ; Toyofuku, T. ; Nakagawa, Y. ; Kang, S. ; Friedel, R.H. ; Sakoda, S. ; Kikutani, H. ; Kumanogoh, A.
Roles of Sema4D-plexin-B1 interactions in the central nervous system for pathogenesis of experimental autoimmune encephalomyelitis.Schmidt, M.V. ; Trümbach, D. ; Weber, P. ; Wagner, K. ; Scharf, S.H. ; Liebl, C. ; Datson, N. ; Namendorf, C. ; Gerlach, T. ; Kühne, C. ; Uhr, M. ; Deussing, J.M. ; Wurst, W. ; Binder, E.B. ; Holsboer, F. ; Müller, M.B.
Individual stress vulnerability is predicted by short-term memory and AMPA receptor subunit ratio in the hippocampus.Ehm, O.K.H.
Examining the role of Notch signalling in adult hippocampal stem cell maintenance.Bianchi, E.
Characterization of molecular mechanisms that govern the formation of neuronal circuits in the developing vertebrate spinal sensory-motor system.Ableitner, M.
Untersuchung des CRH/CRH-Rezeptor Systems mit Hilfe Zelltyp-spezifisch CRH-überexprimierender Mauslinien.Distel, M.
Establishment of combinatorial genetics in zebrafish for analyzing cellular mechanisms of hindbrain development.Herold, S.
Regulationsmechanismen für die adulte Neurogenese von Interneuronen des Olfaktorischen Bulbus.Volkmann, K.
Migratory neuronal precursor populations arising from the zebrafish cerebellar rhombic lip.Röthig, A.H.J.
Generation and analysis of a Pink1 deficient mouse model for Parkinson's disease.Weber, P.
RNA interference as a tool for functional neurogenetics and the role of microRNAs in brain function.Kühn, R.
Konditionale Mutagenese in der Maus.Kröger, M.
Functions of pleiotrophin in the regulation of hematopoiesis.Kaltz, N.
Novel markers for definition of mesenchymal progenitor cells of human stromal cells from different tissues.Lerch, M.M.
Functional analysis of miR-300 in the developing cortex.Helmbrecht, M.S.
The role of microRNAs in the formation of the spinal sensory-motor circuit.Stempfhuber, B.
The function of cilia-mediated pathways in adult neural stem cells.Röhrig, V
The analysis of the canonical Wnt-signaling pathway in the development of murine meso-diencephalic dopaminergic neurons by in vivo and in vitro reporter assays.Rehfeld, F.
Investigating a miRNA mediated regulation mechanism of stage specific transcription factor Sox11 in adult neurogenesis.Schmidt, J.
BAC-transgenic human embryonic stem cell-derived neural stem cells for the study of protein-protein interactions in neurodegenerative diseases.Graw, J.
Strahleninduzierte Katarakte.Graw, J. ; Puk, O. ; Ahmad, N. ; Wagner, S. ; Hrabě de Angelis, M.
Mouse Models for Human Eye Diseases: First mutation in the beta-A2-crystallin encoding gene is associated with small lenses and age-related cataracts.Köster, R.
Zelluläre Mechanismen neuronaler Zellwanderung in der Hirnentwicklung und Regeneration.Puk, O. ; Favor, J. ; Sun, M. ; Graw, J.
The German Mouse Clinic: recent findings from the Eye Screen.Puk, O. ; Ahmad, N. ; Wagner, S. ; Hrabě de Angelis, M. ; Graw, J.
First genetically characterized mouse model for age-related cataracts is a mutation in the ßA2-crystallin encoding gene.Graw, J.
Screening for optic nerve-deficient mouse mutants - and their initial characterization.Graw, J.
Eye development.Distel, M. ; Hocking, J.C. ; Volkmann, K. ; Köster, R.W.
In vivo centrosome dynamics during neuronal migration and axonogenesis in the zebrafish cerebellum.Puk, O. ; Wagner, S. ; Fuchs, H. ; Gailus-Durner, V. ; Dalke, C. ; Hrabě de Angelis, M. ; Graw, J.
Mouse models to identify novel disease genes.Distel, M. ; Hocking, J.C. ; Volkmann, K. ; Köster, R.W.
In vivo centrosome dynamics during neuronal migration and axonogenesis in the zebrafish cerebellum.Graw, J. ; Puk, O. ; Wagner, S. ; Fuchs, H. ; Hrabě de Angelis, M.
New lessons from mouse mutants for eye and lens development: The role of BMPR1B, FGF9, FGF10 and GJF1.Puk, O. ; Ahmad, N. ; Wagner, S. ; Hrabě de Angelis, M. ; Graw, J.
First genetically characterized mouse model for age-related cataracts is a mutation in the beta-A2-crystallin encoding gene.Graw, J. ; Weber, S. ; Puk, O. ; Wagner, S. ; Klaften, M. ; Thiele, F. ; Fuchs, H. ; Hrabě de Angelis, M.
Mutation in the Bmpr1b gene affects optic nerve development.Santoriello, C. ; Gennaro, E. ; Anelli, V. ; Distel, M. ; Kelly, A. ; Köster, R.W. ; Hurlstone, A. ; Mione, M.
Kita driven expression of oncogenic HRAS leads to early onset and highly penetrant melanoma in zebrafish.Buddrus-Schiemann, K. ; Schmid, M. ; Schreiner, K. ; Welzl, G. ; Hartmann, A.
Root colonization by Pseudomonas sp. DSMZ 13134 and impact on the indigenous rhizosphere bacterial community of barley.Beckervordersandforth-Bonk, R. ; Tripathi, P. ; Ninkovic, J. ; Bayam, E. ; Lepier, A. ; Stempfhuber, B. ; Kirchhoff, F. ; Hirrlinger, J. ; Haslinger, A. ; Lie, D.C. ; Beckers, J. ; Yoder, B. ; Irmler, M. ; Götz, M.
In vivo fate mapping and expression analysis reveals molecular hallmarks of prospectively isolated adult neural stem cells.Wirth, E.K. ; Conrad, M. ; Winterer, J. ; Wozny, C. ; Carlson, B.A. ; Roth, S. ; Schmitz, D. ; Bornkamm, G.W. ; Coppola, V. ; Tessarollo, L. ; Schomburg, L. ; Köhrle, J. ; Hatfield, D.L. ; Schweizer, U.
Neuronal selenoprotein expression is required for interneuron development and prevents seizures and neurodegeneration.Spanagel, R. ; Bartsch, D. ; Brors, B. ; Dahmen, N. ; Deussing, J.M. ; Eils, R. ; Ende, G. ; Gallinat, J. ; Gebicke-Haerter, P. ; Heinz, A. ; Kiefer, F. ; Jäger, W. ; Mann, K. ; Matthäus, F. ; Nöthen, M. ; Rietschel, M. ; Sartorius, A. ; Schütz, G. ; Sommer, W.H. ; Sprengel, R. ; Walter, H. ; Wichmann, H.-E. ; Wienker, T. ; Wurst, W. ; Zimmer, A.
An integrated genome research network for studying the genetics of alcohol addiction.Tsolakidou, A. ; Czibere, L. ; Pütz, B. ; Trümbach, D. ; Panhuysen, M. ; Deussing, J.M. ; Wurst, W. ; Sillaber, I. ; Landgraf, R. ; Holsboer, F. ; Rein, T.
Gene expression profiling in the stress control brain region hypothalamic paraventricular nucleus reveals a novel gene network including amyloid beta precursor protein.Trümbach, D. ; Graf, C. ; Pütz, B. ; Kühne, C. ; Panhuysen, M. ; Weber, P. ; Holsboer, F. ; Wurst, W. ; Welzl, G. ; Deussing, J.M.
Deducing corticotropin-releasing hormone receptor type 1 signaling networks from gene expression data by usage of genetic algorithms and graphical Gaussian models.Hackl, C. ; Papazoglou, A. ; Ganser, C. ; Klein, A. ; Prakash, N. ; Wurst, E. ; Nikkhah, G.
Ectopic dopaminergic progenitor cells from En1+/Otx2lacZ transgenic mice survive and functionally reinnervate the striatum following transplantation in a rat model of Parkinson's disease.di Salvio, M. ; di Giovannantonio, L.G. ; Acampora, D. ; Prosperi, R. ; Omodei, D. ; Prakash, N. ; Wurst, W. ; Simeone, A.
Otx2 controls neuron subtype identity in ventral tegmental area and antagonizes vulnerability to MPTP.Castelo-Branco, G. ; Andersson, E.R. ; Minina, E. ; Sousa, K.M. ; Ribeiro, D. ; Kokubu, C. ; Imai, K. ; Prakash, N. ; Wurst, W. ; Arenas, E.
Delayed dopaminergic neuron differentiation in Lrp6 mutant mice.Braig, E. ; Welzl, G. ; Stichler, W. ; Raeder, U. ; Melzer, A.
Entrainment, annual circulation and groundwater inflow in a chain of lakes as inferred by stable ¹⁸O isotopic signatures in the water column.Desbonnet, L. ; Garrett, L. ; Clarke, G. ; Kiely, B. ; Cryan, J.F. ; Dinan, T.G.
Effects of the probiotic Bifidobacterium infantis in the maternal separation model of depression.Haupt, C. ; Langhoff, J. ; Huber, A.B.
Adenylate Cyclase 1 modulates peripheral nerve branching patterns.Mandal, P.K. ; Schneider, M. ; Kölle, P. ; Kuhlencordt, P. ; Förster, H. ; Beck, H. ; Bornkamm, G.W. ; Conrad, M.
Loss of thioredoxin reductase 1 renders tumors highly susceptible to pharmacologic glutathione deprivation.Töwe, S. ; Albert, A. ; Kleineidam, K. ; Brankatschk, R. ; Dümig, A. ; Welzl, G. ; Munch, J.-C. ; Zeyer, J. ; Schloter, M.
Abundance of microbes involved in nitrogen transformation in the rhizosphere of Leucanthemopsis alpina (L.) Heywood grown in soils from different sites of the Damma glacier forefield.Santhiya, S.T. ; Kumar, G.S. ; Sudhakar, P. ; Gupta, N. ; Klopp, N. ; Illig, T. ; Söker, T. ; Groth, M. ; Platzer, M. ; Gopinath, P.M. ; Graw, J.
Molecular analysis of cataract families in India: New mutations in the CRYBB2 and GJA3 genes and rare polymorphisms.Mandal, P.K. ; Seiler, A. ; Perisic, T. ; Kölle, P. ; Canak, A.B. ; Förster, H. ; Weiss, N. ; Kremmer, E. ; Liebermann, M.W. ; Bannai, S. ; Kuhlencordt, P. ; Sato, H. ; Bornkamm, G.W. ; Conrad, M.
System xc− and thioredoxin reductase 1 cooperatively rescue glutathione deficiency.Distel, M. ; Hocking, J.C. ; Volkmann, K. ; Köster, R.W.
The centrosome neither persistently leads migration nor determines the site of axonogenesis in migrating neurons in vivo.Halbach, S. ; Welzl, G.
Levels of organic and inorganic mercury in human blood predicted from measurements of total mercury.Kengara, F.O. ; Schramm, K.-W. ; Dörfler, U. ; Munch, J.-C. ; Henkelmann, B. ; Welzl, G. ; Bernhöft, S. ; Hense, B.A. ; Schroll, R.
Degradation capacity of a 1,2,4-trichlorobenzene mineralizing microbial community for traces of organochlorine pesticides.Ehm, O.K.H. ; Göritz, C. ; Covic, M. ; Schäffner, I. ; Schwarz, T.J. ; Karaca, E. ; Kempkes, B. ; Kremmer, E. ; Pfrieger, F.W. ; Espinosa, L. ; Bigas, A. ; Giachino, C. ; Taylor, V. ; Frisen, J. ; Lie, D.C.
RBPJκ-dependent signaling is essential for long-term maintenance of neural stem cells in the adult hippocampus.Sinha, D.K. ; Neveu, P. ; Gagey, N. ; Aujard, I. ; Le Saux, T. ; Rampon, C. ; Gauron, C. ; Kawakami, K. ; Leucht, C. ; Bally-Cuif, L. ; Volovitch, M. ; Bensimon, D. ; Jullien, L. ; Vriz, S.
Photoactivation of the CreER T² recombinase for conditional site-specific recombination with high spatiotemporal resolution.März, M. ; Chapouton, P. ; Diotel, N. ; Vaillant, C. ; Hesl, B. ; Takamiya, M. ; Lam, C.S. ; Kah, O. ; Bally-Cuif, L. ; Strähle, U.
Heterogeneity in progenitor cell subtypes in the ventricular zone of the zebrafish adult telencephalon.Roshan, M. ; Vijaya, P.H. ; Lavanya, G.R. ; Shama, P.K. ; Santhiya, S.T. ; Graw, J. ; Gopinath, P.M. ; Satyamoorthy, K.
A novel human CRYGD mutation in a juvenile autosomal dominant cataract.Meyer, M. ; Hrabě de Angelis, M. ; Wurst, W. ; Kühn, R.
Gene targeting by homologous recombination in mouse zygotes mediated by zinc-finger nucleases.Mira, H. ; Andreu, Z. ; Suh, H. ; Lie, D.C. ; Jessberger, S. ; Consiglio, A. ; San Emeterio, J. ; Hortigüela, R. ; Marques-Torrejon, M.A. ; Nakashima, K. ; Colak, D. ; Götz, M. ; Farinas, I. ; Gage, F.H.
Signaling through BMPR-IA regulates quiescence and long-term activity of neural stem cells in the adult hippocampus.Ali, L. ; Mansoor, A. ; Ahmad, N. ; Siddiqi, S. ; Mazhar, K. ; Muazzam, A.G. ; Qamar, R. ; Khan, K.M.
Patient HLA-DRB1* and -DQB1* allele and haplotype association with hepatitis C virus persistence and clearance.Dames, P. ; Puff, R. ; Weise, M. ; Parhofer, K.G. ; Göke, B. ; Götz, M. ; Graw, J. ; Favor, J. ; Lechner, A.
Relative roles of the different Pax6 domains for pancreatic alpha cell development.Kinzel, D. ; Boldt, K. ; Davis, E.E. ; Burtscher, I. ; Trümbach, D. ; Diplas, B. ; Attie-Bitach, T. ; Wurst, W. ; Katsanis, N. ; Ueffing, M. ; Lickert, H.
Pitchfork regulates primary cilia disassembly and left-right asymmetry.Takamatsu, H. ; Takegahara, N. ; Nakagawa, Y. ; Tomura, M. ; Taniguchi, M. ; Friedel, R.H. ; Rayburn, H. ; Tessier-Lavigne, M. ; Yoshida, Y. ; Okuno, T. ; Mizui, M. ; Kang, S. ; Nojima, S. ; Tsujimura, T. ; Nakatsuji, Y. ; Katayama, I. ; Toyofuku, T. ; Kikutani, H. ; Kumanogoh, A.
Semaphorins guide the entry of dendritic cells into the lymphatics by activating myosin II.Haupt, C. ; Kloos, K. ; Faus-Kessler, T. ; Huber, A.B.
Semaphorin 3A-Neuropilin-1 signaling regulates peripheral axon fasciculation and pathfinding but not developmental cell death patterns.Stübner, S. ; Faus-Kessler, T. ; Fischer, T. ; Wurst, W. ; Prakash, N.
Fzd3 and Fzd6 deficiency results in a severe midbrain morphogenesis defect.Kleinhammer, A. ; Wurst, W. ; Kühn, R.
Gene knockdown in the mouse through RNAi.Zielonka, M. ; Xia, J.J. ; Friedel, R.H. ; Offermanns, S. ; Worzfeld, T.
A systematic expression analysis implicates Plexin-B2 and its ligand Sema4C in the regulation of the vascular and endocrine system.Hösel, B.G. ; Bhujabal, Z. ; Przemeck, G.K.H. ; Kurz-Drexler, A. ; Vogt Weisenhorn, D.M. ; Hrabě de Angelis, M. ; Beckers, J.
Combination of in silico and in situ hybridisation approaches to identify potential Dll1 associated miRNAs during mouse embryogenesis.Shimokawa, N. ; Haglund, K. ; Hölter, S.M. ; Grabbe, C. ; Kirkin, V. ; Koibuchi, N. ; Schultz, C. ; Rozman, J. ; Hoeller, D. ; Qiu, C.H. ; Londono, M.B. ; Ikezawa, J. ; Jedlicka, P. ; Stein, B. ; Schwarzacher, S.W. ; Wolfer, D.P. ; Ehrhardt, N. ; Heuchel, R. ; Nezis, I. ; Brech, A. ; Schmidt, M.H.H. ; Fuchs, H. ; Gailus-Durner, V. ; Klingenspor, M. ; Bogler, O. ; Wurst, W. ; Deller, T. ; Hrabě de Angelis, M. ; Dikic, I.
CIN85 regulates dopamine receptor endocytosis and governs behaviour in mice.Schreiner, K. ; Hagn, A. ; Kyselkova, M. ; Moenne-Loccoz, Y. ; Welzl, G. ; Munch, J.-C. ; Schloter, M.
Comparison of barley succession and take-all disease as environmental factors shaping the rhizobacterial community during take-all decline.Cox, B.J. ; Vollmer, M. ; Tamplin, O. ; Lu, M. ; Biechele, S. ; Gertsenstein, M. ; van Campenhout, C.A. ; Floß, T. ; Kühn, R. ; Wurst, W. ; Lickert, H. ; Rossant, J.
Phenotypic annotation of the mouse X chromosome.Covic, M. ; Karaca, E. ; Lie, D.C.
Epigenetic regulation of neurogenesis in the adult hippocampus.Wurst, W. ; Hrabě de Angelis, M.
Systematic phenotyping of mouse mutants.Kühn, E. ; Köster, R.W.
Analysis of gene expression by in situ hybridization on adult zebrafish brain sections.Deussing, J.M. ; Breu, J. ; Kühne, C. ; Kallnik, M. ; Bunck, M. ; Glasl, L. ; Yen, Y.C. ; Schmidt, M.V. ; Zurmühlen, R. ; Vogl, A.M. ; Gailus-Durner, V. ; Fuchs, H. ; Hölter, S.M. ; Wotjak, C.T. ; Landgraf, R. ; Hrabě de Angelis, M. ; Holsboer, F. ; Wurst, W.
Urocortin 3 modulates social discrimination abilities via corticotropin-releasing hormone receptor type 2.Volkmann, K. ; Chen, Y.Y. ; Harris, M.P. ; Wullimann, M.F. ; Köster, R.W.
The zebrafish cerebellar upper rhombic lip generates tegmental hindbrain nuclei by long-distance migration in an evolutionary conserved manner.Olbrich, M. ; Kerner, R. ; Gerstner, E. ; Welzl, G. ; Winkler, J.B. ; Müller-Starck, G. ; Ernst, D.
Transcript and protein responses in leaves of ozone-treated young European beech trees at an outdoor free air model fumigation site over two growing seasons.Schebelle, L. ; Wolf, C. ; Stribl, C.B. ; Javaheri, T. ; Schnütgen, F. ; Ettinger, A. ; Ivics, Z. ; Hansen, J. ; Ruiz, P. ; von Melchner, H. ; Wurst, W. ; Floß, T.
Efficient conditional and promoter-specific in vivo expression of cDNAs of choice by taking advantage of recombinase-mediated cassette exchange using FlEx gene traps.Jawerka, M. ; Colak, D. ; Dimou, L. ; Spiller, C. ; Lagger, S. ; Montgomery, R.L. ; Olson, E.N. ; Wurst, W. ; Göttlicher, M. ; Götz, M.
The specific role of histone deacetylase 2 in adult neurogenesis.Aron, L. ; Klein, P. ; Pham, T.T. ; Kramer, E.R. ; Wurst, W. ; Klein, R.
Pro-survival role for Parkinson's associated gene DJ-1 revealed in trophically impaired dopaminergic neurons.Romanowski, C.P.N. ; Fenzl, T. ; Flachskamm, C. ; Wurst, W. ; Holsboer, F. ; Deussing, J.M. ; Kimura, M.
Central deficiency of corticotropin-releasing hormone receptor type 1 (CRH-R1) abolishes effects of CRH on NREM but not on REM sleep in mice.Chapouton, P. ; Skupien, P. ; Hesl, B. ; Coolen, M. ; Moore, J.C. ; Madelaine, R. ; Kremmer, E. ; Faus-Kessler, T. ; Blader, P. ; Lawson, N.D. ; Bally-Cuif, L.
Notch activity levels control the balance between quiescence and recruitment of adult neural stem cells.Olbrich, M. ; Gerstner, E. ; Bahnweg, G. ; Häberle, K.-H. ; Matyssek, R. ; Welzl, G. ; Heller, W. ; Ernst, D.
Transcriptional signatures in leaves of adult European beech trees (Fagus sylvatica L.) in an experimentally enhanced free air ozone setting.Olbrich, M. ; Knappe, C. ; Wenig, M. ; Gerstner, E. ; Häberle, K.-H. ; Kitao, M. ; Matyssek, R. ; Stich, S. ; Leuchner, M. ; Werner, H. ; Schlink, K. ; Müller-Starck, G. ; Welzl, G. ; Scherb, H. ; Ernst, D. ; Heller, W. ; Bahnweg, G.
Ozone fumigation (twice ambient) reduces leaf infestation following natural and artificial inoculation by the endophytic fungus Apiognomonia errabunda of adult European beech trees.Wurst, W. ; Prakash, N.
Genetic control of meso-diencephalic dopaminergic neuron development in rodents.Morgan, H. ; Beck, T. ; Blake, A. ; Gates, H. ; Adams, N. ; Debouzy, G. ; Leblanc, S. ; Lengger, C. ; Maier, H. ; Melvin, D. ; Meziane, H. ; Richardson, D. ; Wells, S. ; White, J. ; Wood, J. ; EUMODIC Consortium (Hrabě de Angelis, M. ; Gailus-Durner, V. ; Fuchs, H. ; Adler, T. ; Aguilar-Pimentel, J.A. ; Becker, L. ; Beckeredjian, R ; Busch, D.H. ; Calzada-Wack, J. ; Da Silva-Buttkus, P. ; Esposito, I. ; Favor, J. ; Fleischmann, W. ; Garrett, L. ; Glasl, L. ; Götz, A. ; Graw, J. ; Hans, W, ; Hölter, S.M. ; Ivandic, B. ; Katus, H.A. ; Klingenspor, M. ; Klopstock, T. ; Lengger, C. ; Ludwig, T. ; Maier, H. ; Micklich, K. ; Minxuan, S. ; Naton, B. ; Neff, F. ; Ollert, M. ; Puk, O. ; Quintanilla-Fend, L. ; Rácz, I. ; Rathkolb, B. ; Rozman, J. ; Schäble, K.-H. ; Schiller, E. ; Schrewe, A. ; Steinkamp, R. ; Stoeger, C. ; Stöger, T. ; Schulz, S. ; Tost, M. ; Treise, I. ; Vogt Weisenhorn, D.M. ; Willershäuser, M. ; Wolf, E. ; Zimprich, A. ; Wurst, W. ; Zeh, R.M. ; Zimmer, A.) ; Brown, S. ; Hancock, J.M. ; Mallon, A.M.
EuroPhenome: A repository for high-throughput mouse phenotyping data.Das, M. ; Reichman, J.R. ; Haberer, G. ; Welzl, G. ; Aceituno, F.F. ; Mader, M.T. ; Watrud, L.S. ; Pfleeger, T.G. ; Gutiérrez, R.A. ; Schäffner, A. ; Olszyk, D.M.
A composite transcriptional signature differentiates responses towards closely related herbicides in Arabidopsis thaliana and Brassica napus.Hölter, S.M. ; Cryan, J.F.
Phenotyping of behavioral characteristics.Shyla, A. ; Hölzlwimmer, G. ; Calzada-Wack, J. ; Bink, K. ; Tischenko, O. ; Guilly, M.N. ; Chevillard, S. ; Samson, E. ; Graw, J. ; Atkinson, M.J. ; Pellegata, N.S.
Allelic loss of chromosomes 8 and 19 in MENX-associated rat pheochromocytoma.Rosemann, M. ; Ivashkevich, A. ; Favor, J. ; Dalke, C. ; Hölter, S.M. ; Becker, L. ; Rácz, I. ; Bolle, I. ; Klempt, M. ; Rathkolb, B. ; Kalaydjiev, S. ; Adler, T. ; Aguilar, A. ; Hans, W. ; Horsch, M. ; Rozman, J. ; Calzada-Wack, J. ; Kunder, S. ; Naton, B. ; Gailus-Durner, V. ; Fuchs, H. ; Schulz, S. ; Beckers, J. ; Busch, D.H. ; Burbach, J.P. ; Smidt, M.P. ; Quintanilla-Martinez, L. ; Esposito, I. ; Klopstock, T. ; Klingenspor, M. ; Ollert, M. ; Wolf, E. ; Wurst, W. ; Zimmer, A. ; Hrabě de Angelis, M. ; Atkinson, M.J. ; Heinzmann, U. ; Graw, J.
Microphthalmia, parkinsonism, and enhanced nociception in Pitx3(416insG ) mice.Kimura, M. ; Müller-Preuss, P. ; Lu, A. ; Wiesner, E. ; Flachskamm, C. ; Wurst, W. ; Holsboer, F. ; Deussing, J.M.
Conditional corticotropin-releasing hormone overexpression in the mouse forebrain enhances rapid eye movement sleep.Pham, T.T. ; Giesert, F. ; Röthig, A. ; Floß, T. ; Kallnik, M. ; Weindl, K. ; Hölter, S.M. ; Ahting, U. ; Prokisch, H. ; Becker, L. ; Klopstock, T. ; Hrabě de Angelis, M. ; Beyer, K. ; Görner, K. ; Kahle, P.J. ; Vogt Weisenhorn, D.M. ; Wurst, W.
DJ-1-deficient mice show less TH-positive neurons in the ventral tegmental area and exhibit non-motoric behavioural impairments.Pirson, S.
Generation of autologous and allorestricted cytotoxic T cell clones directed against Ewing tumor antigens.Obradovic, D. ; Zanca, C. ; Vogl, A. ; Trümbach, D. ; Deussing, J.M. ; Condorelli, G. ; Rein, T.
Vitamin D₃ signalling in the brain enhances the function of phosphoprotein enriched in astrocytes - 15 kD (PEA-15).Kuwabara, T. ; Hsieh, J. ; Muotri, A. ; Yeo, G. ; Warashina, M. ; Lie, D.C. ; Moore, L. ; Nakashima, K. ; Asashima, M. ; Gage, F.H.
Wnt-mediated activation of NeuroD1 and retro-elements during adult neurogenesis.Nikolaou, N. ; Watanabe-Asaka, T. ; Gerety, S. ; Distel, M. ; Köster, R.W. ; Wilkinson, D.G.
Lunatic fringe promotes the lateral inhibition of neurogenesis.Welzl, G. ; Hense, B.A.
Statistische Bewertungsverfahren im biologischen Kontext: Teil III: Hauptkomponentenanalyse (Principal Component Analysis -PCA).Rieger, S. ; Senghaas, N. ; Walch, A.K. ; Köster, R.W.
Cadherin-2 controls directional chain migration of cerebellar granule neurons.Coolen, M. ; Bally-Cuif, L.
MicroRNAs in brain development and physiology.Anelli, V. ; Santoriello, C. ; Distel, M. ; Köster, R.W. ; Ciccarelli, F.D. ; Mione, M.
Global repression of cancer gene expression in a zebrafish model of melanoma is linked to epigenetic regulation.Razansky, D. ; Distel, M. ; Vinegoni, C. ; Ma, R. ; Perrimon, N. ; Köster, R.W. ; Ntziachristos, V.
Multispectral opto-acoustic tomography of deep-seated fluorescent proteins in vivo.Brown, S.D. ; Wurst, W. ; Kühn, R. ; Hancock, J.M.
The functional annotation of mammalian genomes: The challenge of phenotyping.Jessberger, S. ; Clark, R.E. ; Broadbent, N.J. ; Clemenson, G.D. Jr. ; Consiglio, A. ; Lie, D.C. ; Squire, L.R. ; Gage, F.H.
Dentate gyrus-specific knockdown of adult neurogenesis impairs spatial and object recognition memory in adult rats.Puk, O. ; Dalke, C. ; Calzada-Wack, J. ; Ahmad, N. ; Klaften, M. ; Wagner, S. ; Hrabě de Angelis, M. ; Graw, J.
Reduced corneal thickness and enlarged anterior chamber in a novel ColVIIIa2(G257D) mutant mouse.Haslinger, A. ; Schwarz, T.J. ; Covic, M. ; Lie, D.C.
Expression of Sox11 in adult neurogenic niches suggests a stage-specific role in adult neurogenesis.Winner, B. ; Vogt Weisenhorn, D.M. ; Lie, D.C. ; Blümcke, I. ; Winkler, J.
Cellular repair strategies in Parkinson's disease.Khan, M.A. ; Berti, L.
Alzheimer's disease affects progenitor cells through aberrant β-catenin signaling.Wittmann, D.M. ; Blöchl, F. ; Trümbach, D. ; Wurst, W. ; Prakash, N. ; Theis, F.J.
Spatial analysis of expression patterns predicts genetic interactions at the mid-hindbrain boundary.Jagasia, R. ; Steib, K. ; Englberger, E. ; Herold, S. ; Faus-Kessler, T. ; Saxe, M. ; Gage, F.H. ; Song, H. ; Lie, D.C.
GABA-cAMP response element-binding protein signaling regulates maturation and survival of newly generated neurons in the adult hippocampus.Ainsbury, E.A. ; Bouffler, S.D. ; Dörr, W. ; Graw, J. ; Muirhead, C.R. ; Edwards, A.A. ; Cooper, J.
Radiation cataractogenesis: A review of recent studies.Distel, M. ; Wullimann, M.F. ; Köster, R.W.
Optimized Gal4 genetics for permanent gene expression mapping in zebrafish.Senghaas, N. ; Köster, R.W.
Culturing and transfecting zebrafish PAC2 fibroblast cells.Köster, R.W. ; Fraser, S.E.
Time-lapse microscopy of brain development.Morais, V. ; Verstreken, P. ; Roethig, A. ; Smet, J. ; Snellinx, A. ; Vanbrabant, M. ; Haddad, D. ; Frezza, C. ; Mandemakers, W. ; Vogt Weisenhorn, D.M. ; van Coster, R. ; Wurst, W. ; Scorrano, L. ; de Strooper, B.
Parkinson's disease mutations in PINK1 result in decreased Complex I activity and deficient synaptic function.Wizenmann, A. ; Brunet, I. ; Lam, J.S.Y. ; Sonnier, L. ; Beurdeley, M. ; Zarbalis, K. ; Vogt Weisenhorn, D.M. ; Weinl, C. ; Dwivedy, A. ; Joliot, A. ; Wurst, W. ; Holt, C. ; Prochiantz, A.
Extracellular engrailed participates in the topographic guidance of retinal axons in vivo.Carlson, B.A. ; Schweizer, U. ; Perella, C. ; Shrimali, R.K. ; Feigenbaum, L. ; Shen, L. ; Speransky, S. ; Floß, T. ; Jeong, S.J. ; Watts, J. ; Hoffmann, V. ; Combs, G.F. ; Gladyshev, V.N. ; Hatfield, D.L.
The selenocysteine tRNA STAF-binding region is essential for adequate selenocysteine tRNA status, selenoprotein expression and early age survival of mice.Stübner, S.
Wnt1 Signaltransduktion durch Frizzled Rezeptoren in der Entwicklung mittelhirn-dopaminerger Neurone.Babaryka, A.N.
Characterisation of the zebrafish cerebellar efferent system.Graf, C.
In vitro and in vivo analysis of corticotropin-releasing hormone receptor-dependent signal transduction using microarray technology.Kohli, M.A.
A candidate gene and a genome-wide association study in depression.Pogoda, F.S.
Induktion eines Apoptose-ähnlichen Phänotyps durch ORF21, der Thymidinkinase des Kaposi Sarkom-assoziierten humanen Herpesvirus-8.Schebelle, L.
Manipulation of the mouse genome by transposon and recombinase techniques.Sprungala, S.
Telomere length, telomerase and maintenance of stem cells in the adult zebrafish brain.Steuber-Buchberger, P.M.
Genetic analysis of Glycogen Synthase Kinase-3 in the adult mouse brain.Webb, K.J.
Molecular and cellular characterisation of neurogenesis control and addiction behaviour in zebrafish.Imhof, S.
Endoderm lineage labelling using BAC reporter constructs in ES cells and mouse embryos.Uetzmann, L.
Differentiation of the endoderm lineage in the murine system.Bengel, D.
Die Identifikation und Charakterisierung neuer Spemann/Mangold Organisatorgene.Doberauer, K.
The role of β-catenin - Tcf/LEF signaling in adult hippocampal neurogenesis.Pham, T.T.
Functional analysis of DJ-1 deficient mice - a mouse model for Parkinson's disease.Batrak, V.
Identification and analysis of the cis-regulatory element for the AID-mediated somatic hypermutation and application of this process for the artificial protein evolution in chicken B cell line DT40.Huber, M.
Optimierung der Pluripotenz Embryonaler Stammzelllienien von Mäusen.Lange, S.
Schaffung der technische Grundlage zur Untersuchung der Interaktionspartner von CREB in adulten Stammzellen.Javaheri, T.
Replacement of mouse TDP-43 by human WT and mutant cDNA in embryonic stem cells.Schäffner, I.
Role of FoxO transcription factors in adult neurogenesis.Stumpenhorst, K.
Behavioural analysis of zebrafish larvae with mutations or drug induced changes in the dopaminergic system.Steib, K.
The importance of mitochondria in the maturation of newborn neurons in the adult brain.Ehrenberg, S.
Determination of neurotransmitter identities of corticotropin-releasing hormone receptor 1 expressing neurons and analysis of corticotropin-releasing hormone system-dependent neurotransmitter release in the mouse brain.Dedic, N.
Gene expression profiling and behavioural characterization of conditional corticotropin-releasing hormone overexpressing mice following acute and chronic stress.Graw, J. ; Puk, O.
Role of fibroblast growth factors Fgf9 and Fgf10 in mouse eye development.Graw, J.
Splicing defect in Calpain12 cDNA of a recessive cataract mutation in rats (cat).Kühn, R. ; Wurst, W.[Eds.]
Gene knockout protocols.Gailus-Durner, V. ; Fuchs, H. ; Adler, T. ; Aguilar-Pimentel, J.A. ; Becker, L. ; Bolle, I. ; Calzada-Wack, J. ; Dalke, C. ; Ehrhardt, N. ; Ferwagner, B. ; Hans, W, ; Hölter, S.M. ; Hölzlwimmer, G. ; Horsch, M. ; Javaheri, A. ; Kallnik, M. ; Kling, E. ; Lengger, C. ; Mörth, C. ; Mossbrugger, I. ; Naton, B. ; Prehn, C. ; Puk, O. ; Rathkolb, B. ; Rozman, J. ; Schrewe, A. ; Thiele, F. ; Adamski, J. ; Aigner, B. ; Behrendt, H. ; Busch, D.H. ; Favor, J. ; Graw, J. ; Heldmaier, G. ; Ivandic, B. ; Katus, H.A. ; Klingenspor, M. ; Klopstock, T. ; Kremmer, E. ; Ollert, M. ; Quintanilla-Martinez, L. ; Schulz, H. ; Wolf, E. ; Wurst, W. ; Hrabě de Angelis, M.
Systemic first-line phenotyping.Olbrich, M. ; Gerstner, E. ; Welzl, G. ; Winkler, J.B. ; Ernst, D.
Transcript responses in leaves of ozone-treated beech saplings seasons at an outdoor free air model fumigation site over two growing seasons.Esperschütz, J. ; Pritsch, K. ; Gattinger, A. ; Welzl, G. ; Haesler, F. ; Buegger, F. ; Winkler, J.B. ; Munch, J.-C. ; Schloter, M.
Influence of chronic ozone stress on carbon translocation pattern into rhizosphere microbial communities of beech trees (Fagus sylvatica L.) during a growing season.Graw, J. ; Schmidt, W. ; Minogue, P.J. ; Rodriguez, J. ; Tong, J.J. ; Klopp, N. ; Illig, T. ; Ebihara, L. ; Berthoud, V.M. ; Beyer, E.C.
The GJA8 allele encoding CX50I247M is a rare polymorphism, not a cataract-causing mutation.Puk, O. ; Esposito, I. ; Söker, T. ; Löster, J. ; Budde, B. ; Nürnberg, P. ; Michel-Soewarto, D. ; Fuchs, H. ; Wolf, E. ; Hrabě de Angelis, M. ; Graw, J.
A new Fgf10 mutation in the mouse leads to atrophy of the harderian gland and slit-eye phenotype in heterozygotes: A novel model for dry-eye disease?Grzmil, P. ; Konietzko, J. ; Boehm, D. ; Hölter, S.M. ; Aguilar, A. ; Javaheri, A. ; Kalaydjiev, S. ; Adler, T. ; Bolle, I. ; Adham, I. ; Dixkens, C. ; Wolf, S. ; Fuchs, H. ; Gailus-Durner, V. ; Wurst, W. ; Ollert, M. ; Busch, D. ; Schulz, S. ; Hrabě de Angelis, M. ; Burfeind, P.
Targeted disruption of the mouse Npal3 gene leads to deficits in behavior, increased IgE levels, and impaired lung function.Webb, K.J. ; Norton, W.H.J. ; Trümbach, D. ; Meijer, A.H. ; Ninkovic, J. ; Topp, S. ; Heck, D. ; Marr, C. ; Wurst, W. ; Theis, F.J. ; Spaink, H.P. ; Bally-Cuif, L.
Zebrafish reward mutants reveal novel transcripts mediating the behavioral effects of amphetamine.Hitz, C. ; Steuber-Buchberger, P.M. ; Delic, S. ; Wurst, W. ; Kühn, R.
Generation of shRNA transgenic mice.Gailus-Durner, V. ; Fuchs, H. ; Adler, T. ; Aguilar-Pimentel, J.A. ; Becker, L. ; Bolle, I. ; Calzada-Wack, J. ; Dalke, C. ; Ehrhardt, N. ; Ferwagner, B. ; Hans, W. ; Hölter, S.M. ; Hölzlwimmer, G. ; Horsch, M. ; Javaheri, A. ; Kallnik, M. ; Kling, E. ; Lengger, C. ; Mörth, C. ; Mossbrugger, I. ; Naton, B. ; Prehn, C. ; Puk, O. ; Rathkolb, B. ; Rozman, J. ; Schrewe, A. ; Thiele, F. ; Adamski, J. ; Aigner, B. ; Behrendt, H. ; Busch, D.H. ; Favor, J. ; Graw, J. ; Heldmaier, G. ; Ivandic, B. ; Katus, H.A. ; Klingenspor, M. ; Klopstock, T. ; Kremmer, E. ; Ollert, M. ; Quintanilla-Martinez, L. ; Schulz, S. ; Wolf, E. ; Wurst, W. ; Hrabě de Angelis, M.
Systemic first-line phenotyping.Soehn, A.S. ; Pham, T.T. ; Schaeferhoff, K. ; Floß, T. ; Vogt Weisenhorn, D.M. ; Wurst, W. ; Bonin, M. ; Riess, O.
Periphilin is strongly expressed in the murine nervous system and is indispensable for murine development.Rubio-Aliaga, I. ; Przemeck, G.K.H. ; Fuchs, H. ; Gailus-Durner, V. ; Adler, T. ; Hans, W. ; Horsch, M. ; Rathkolb, B. ; Rozman, J. ; Schrewe, A. ; Wagner, S. ; Hölter, S.M. ; Becker, L. ; Klopstock, T. ; Wurst, W. ; Wolf, E. ; Klingenspor, M. ; Ivandic, B.T. ; Busch, D.H. ; Beckers, J. ; Hrabě de Angelis, M.
Dll1 haploinsufficiency in adult mice leads to a complex phenotype affecting metabolic and immunological processes.Feil, R. ; Hölter, S.M. ; Weindl, K. ; Wurst, W. ; Langmesser, S. ; Gerling, A. ; Feil, S. ; Albrecht, U.
cGMP-dependent protein kinase I, the circadian clock, sleep and learning.Silberstein, S. ; Vogl, A.M. ; Bonfiglio, J.J. ; Wurst, W. ; Holsboer, F. ; Arzt, E. ; Deussing, J.M. ; Refojo, D.
Immunology, signal transduction, and behavior in hypothalamic-pituitary-adrenal axis-related genetic mouse models.Liebl, C. ; Panhuysen, M. ; Pütz, B. ; Trümbach, D. ; Wurst, W. ; Deussing, J.M. ; Müller, M.B. ; Schmidt, M.V.
Gene expression profiling following maternal deprivation: Involvement of the brain Renin-Angiotensin system.Schneider, M. ; Förster, H. ; Boersma, A. ; Seiler, A. ; Wehnes, H. ; Sinowatz, F. ; Neumüller, C. ; Deutsch, M.J. ; Walch, A.K. ; Hrabě de Angelis, M. ; Wurst, W. ; Ursini, F. ; Roveri, A. ; Maleszewski, M. ; Maiorino, M. ; Conrad, M.
Mitochondrial glutathione peroxidase 4 disruption causes male infertility.Prakash, N. ; Puelles, E. ; Freude, K. ; Trümbach, D. ; Omodei, D. ; di Salvio, M. ; Sussel, L. ; Ericson, J. ; Sander, M. ; Simeone, A. ; Wurst, W.
Nkx6-1 controls the identity and fate of red nucleus and oculomotor neurons in the mouse midbrain.Wirth, E.K. ; Roth, S. ; Blechschmidt, C. ; Hölter, S.M. ; Becker, L. ; Rácz, I. ; Zimmer, A. ; Klopstock, T. ; Gailus-Durner, V. ; Fuchs, H. ; Wurst, W. ; Naumann, T. ; Bräuer, A. ; Hrabě de Angelis, M. ; Köhrle, J. ; Grüters, A. ; Schweizer, U.
Neuronal 3',3,5-triiodothyronine (T₃) uptake and behavioral phenotype of mice deficient in Mct8, the neuronal T₃ transporter mutated in Allan-Herndon-Dudley syndrome.Lutz, A.K. ; Exner, N. ; Fett, M.E. ; Schlehe, J.S. ; Kloos, K. ; Lämmermann, K. ; Brunner, B. ; Kurz-Drexler, A. ; Vogel, F. ; Reichert, AS. ; Bouman, L. ; Vogt Weisenhorn, D.M. ; Wurst, W. ; Tatzelt, J. ; Haass, C. ; Winklhofer, K.F.
Loss of parkin or PINK1 function increases Drp1-dependent mitochondrial fragmentation.Waak, J. ; Weber, S.S. ; Waldenmaier, A. ; Görner, K. ; Alunni-Fabbroni, M. ; Schell, H. ; Vogt Weisenhorn, D.M. ; Pham, T.T. ; Reumers, V. ; Baekelandt, V. ; Wurst, W. ; Kahle, P.J.
Regulation of astrocyte inflammatory responses by the Parkinson's disease-associated gene DJ-1.Kirchner, M. ; Faus-Kessler, T. ; Jakobi, G. ; Levy, W. ; Henkelmann, B. ; Bernhöft, S. ; Kotalik, J. ; Zsolnay, A. ; Bassan, R. ; Belis, C. ; Kräuchi, N. ; Moche, W. ; Simonciic, P. ; Uhl, M. ; Weiss, P. ; Schramm, K.-W.
Vertical distribution of organochlorine pesticides in humus along Alpine altitudinal profiles in relation to ambiental parameters.Bazhin, A.V. ; Dalke, C. ; Willner, N. ; Abschütz, O. ; Wildberger, H.G. ; Philippov, P.P. ; Dummer, R. ; Graw, J. ; Hrabě de Angelis, M. ; Schadendorf, D. ; Umansky, V. ; Eichmüller, S.B.
Cancer-retina antigens as potential paraneoplastic antigens in melanoma-associated retinopathy.di Benedetto, B. ; Kallnik, M. ; Vogt Weisenhorn, D.M. ; Falls, W.A. ; Wurst, W. ; Hölter, S.M.
Activation of ERK/MAPK in the lateral amygdala of the mouse is required for acquisition of a fear-potentiated startle response.Silberstein, S. ; Vogl, A.M. ; Refojo, D. ; Senin, S.A. ; Wurst, W. ; Holsboer, F. ; Deussing, J.M. ; Arzt, E.
Amygdaloid pERK1/2 in corticotropin-releasing hormone overexpressing mice under basal and acute stress conditions.Graw, J.
Genetics of crystallins: Cataract and beyond.Flinn, L. ; Mortiboys, H. ; Volkmann, K. ; Köster, R.W. ; Ingham, P.W. ; Bandmann, O.
Complex I deficiency and dopaminergic neuronal cell loss in parkin-deficient zebrafish (Danio rerio).Kala, K. ; Haugas, M. ; Lilleväli, K. ; Guimera, J. ; Wurst, W. ; Salminen, M. ; Partanen, J.
Gata2 is a tissue-specific post-mitotic selector gene for midbrain GABAergic neurons.Babaryka, A. ; Kühn, E. ; Köster, R.W.
In vivo synthesis of meganuclease for generating transgenic zebrafish Danio rerio.Perez-Balaguer, A. ; Puelles, E. ; Wurst, W. ; Martinez, S.
Shh dependent and independent maintenance of basal midbrain.Betz, G.A. ; Knappe, C. ; Lapierre, C. ; Olbrich, M. ; Welzl, G. ; Langebartels, C. ; Heller, W. ; Sandermann, H. ; Ernst, D.
Ozone affects shikimate pathway transcripts and monomeric lignin composition in European beech (Fagus sylvatica L.).Enard, W. ; Gehre, S. ; Hammerschmidt, K. ; Hölter, S.M. ; Blass, T. ; Somel, M. ; Brückner, M.K. ; Schreiweis, C. ; Winter, C. ; Sohr, R. ; Becker, L. ; Wiebe, V. ; Nickel, B. ; Giger, T. ; Müller, U. ; Groszer, M. ; Adler, T. ; Aguilar, A. ; Bolle, I. ; Calzada-Wack, J. ; Dalke, C. ; Ehrhardt, N. ; Favor, J. ; Fuchs, H. ; Gailus-Durner, V. ; Hans, W. ; Hölzlwimmer, G. ; Javaheri, A. ; Kalaydjiev, S. ; Kallnik, M. ; Kling, E. ; Kunder, S. ; Moßbrugger, I. ; Naton, B. ; Rácz, I. ; Rathkolb, B. ; Rozman, J. ; Schrewe, A. ; Busch, D.H. ; Graw, J. ; Ivandic, B. ; Klingenspor, M. ; Klopstock, T. ; Ollert, M. ; Quintanilla-Martinez, L. ; Schulz, S. ; Wolf, E. ; Wurst, W. ; Zimmer, A. ; Fisher, S.E. ; Morgenstern, R. ; Arendt, T. ; Hrabě de Angelis, M. ; Fischer, J. ; Schwarz, J. ; Pääbo, S.
A humanized version of Foxp2 affects cortico-basal ganglia circuits in mice.Beckers, J. ; Wurst, W. ; Hrabě de Angelis, M.
Towards better mouse models: Enhanced genotypes, systemic phenotyping and envirotype modelling.Fuchs, H. ; Gailus-Durner, V. ; Adler, T. ; Aguilar-Pimentel, J.A. ; Becker, L. ; Bolle, I. ; Brielmeier, M. ; Calzada-Wack, J. ; Dalke, C. ; Ehrhardt, N. ; Fasnacht, N. ; Ferwagner, B. ; Frischmann, U. ; Hans, W. ; Hölter, S.M. ; Hölzlwimmer, G. ; Horsch, M. ; Javaheri, A. ; Kallnik, M. ; Kling, E. ; Lengger, C. ; Maier, H. ; Mossbrugger, I. ; Mörth, C. ; Naton, B. ; Nöth, U. ; Pasche, B. ; Prehn, C. ; Przemeck, G.K.H. ; Puk, O. ; Rácz, I. ; Rathkolb, B. ; Rozman, J. ; Schäble, K.-H. ; Schreiner, R. ; Schrewe, A. ; Sina, C. ; Steinkamp, R. ; Thiele, F. ; Willershäuser, M. ; Zeh, R.M. ; Adamski, J. ; Busch, D.H. ; Beckers, J. ; Behrendt, H. ; Daniel, H. ; Esposito, I. ; Favor, J. ; Graw, J. ; Heldmaier, G. ; Höfler, H. ; Ivandic, B. ; Katus, H.A. ; Klingenspor, M. ; Klopstock, T. ; Lengeling, A. ; Mempel, M. ; Müller, W. ; Neschen, S. ; Ollert, M. ; Quintanilla-Martinez, L. ; Rosenstiel, P. ; Schmidt, J. ; Schreiber, S. ; Schughart, K. ; Schulz, S. ; Wolf, E. ; Wurst, W. ; Zimmer, A. ; Hrabě de Angelis, M.
The German Mouse Clinic: A platform for systemic phenotype analysis of mouse models.Paquet, D. ; Bhat, R. ; Sydow, A. ; Mandelkow, E.-M. ; Berg, S. ; Hellberg, S. ; Fälting, J. ; Distel, M. ; Köster, R.W. ; Schmid, B. ; Haass, C.
A zebrafish model of tauopathy allows in vivo imaging of neuronal cell death and drug evaluation.Betz, G.A. ; Gerstner, E. ; Stich, S. ; Winkler, B. ; Welzl, G. ; Kremmer, E. ; Langebartels, C. ; Heller, W. ; Sandermann, H. ; Ernst, D.
Ozone affects shikimate pathway genes and secondary metabolites in saplings of European beech (Fagus sylvatica L.) grown under greenhouse conditions.Rauser, S.
Bedeutung des Phosphatidylinositol-3'-Kinase (PI3K)-Signalwegs für das Migrations- und Invasionsverhalten glialer Tumorzellen.di Benedetto, B. ; Wefers, B. ; Wurst, W. ; Kühn, R.
Local Knockdown of ERK2 in the Adult Mouse Brain Via Adeno-Associated Virus-Mediated RNA Interference.Ahting, U. ; Floß, T. ; Uez, N. ; Schneider-Lohmar, I. ; Becker, L. ; Kling, E. ; Iuso, A. ; Bender, A. ; Hrabě de Angelis, M. ; Gailus-Durner, V. ; Fuchs, H. ; Meitinger, T. ; Wurst, W. ; Prokisch, H. ; Klopstock, T.
Neurological phenotype and reduced lifespan in heterozygous Tim23 knockout mice, the first mouse model of defective mitochondrial import.Risbrough, V.B. ; Geyer, M.A. ; Hauger, R.L. ; Coste, S. ; Stenzel-Poore, M. ; Wurst, W. ; Holsboer, F.
CRF1 and CRF2 receptors are required for potentiated startle to contextual but not discrete cues.Prinzen, C. ; Trümbach, D. ; Wurst, W. ; Endres, K. ; Postina, R. ; Fahrenholz, F.
Differential gene expression in ADAM10 and mutant ADAM10 transgenic mice.Lillesaar, C. ; Stigloher, C. ; Tannhäuser, B. ; Wullimann, M.F. ; Bally-Cuif, L.
Axonal projections originating from raphe serotonergic neurons in the developing and adult zebrafish, Danio rerio, using transgenics to visualize raphe-specific pet1 expression. H₂O.Korostylev, A. ; Worzfeld, T. ; Deng, S. ; Friedel, R.H. ; Swiercz, J.M. ; Vodrazka, P. ; Maier, V. ; Hirschberg, A. ; Ohoka, Y. ; Inagaki, S. ; Offermanns, S. ; Kuner, R.
A functional role for semaphorin 4D/plexin B1 interactions in epithelial branching morphogenesis during organogenesis.Schnütgen, F. ; Hansen, J. ; De-Zolt, S. ; Horn, C. ; Lutz, M. ; Floß, T. ; Wurst, W. ; Ruiz Noppinger, P. ; von Melchner, H.
Enhanced gene trapping in mouse embryonic stem cells.Seiler, A. ; Schneider, M. ; Förster, H. ; Roth, S. ; Wirth, E.K. ; Culmsee, C. ; Plesnila, N. ; Kremmer, E. ; Radmark, O. ; Wurst, W. ; Bornkamm, G.W. ; Schweizer, U. ; Conrad, M.
Glutathione peroxidase 4 senses and translates oxidative stress into 12/15-lipoxygenase dependent- and AIF-Mediated cell death.Klafke, R. ; Wurst, W. ; Prakash, N.
Genetic control of rodent midbrain dopaminergic neuron development in the light of human disease.Böhm, J. ; Buck, A. ; Borozdin, W. ; Mannan, A.U. ; Matysiak-Scholze, U. ; Adham, I. ; Schulz-Schaeffer, W. ; Floß, T. ; Wurst, W. ; Kohlhase, J. ; Barrionuevo, F.
Sall1, Sall2, and Sall4 Are Required for Neural Tube Closure in Mice.Kamprath, K. ; Plendl, W. ; Marsicano, G. ; Deussing, J.M. ; Wurst, W. ; Lutz, B. ; Wotjak, C.T.
Endocannabinoids mediate acute fear adaptation via glutamatergic neurons independently of corticotropin-releasing hormone signaling.Steuber-Buchberger, P.M. ; Wurst, W. ; Kühn, R.
Simultaneous Cre-mediated conditional knockdown of two genes in mice.Hanstein, R. ; Lu, A. ; Wurst, W. ; Holsboer, F. ; Deussing, J.M. ; Clement, A.B. ; Behl, C.
Transgenic overexpression of corticotropin releasing hormone provides partial protection against neurodegeneration in an in vivo model of acute excitotoxic stress.Andersson, E.R. ; Prakash, N. ; Cajanek, L. ; Minina, E. ; Bryja, V. ; Bryjova, L. ; Yamaguchi, T.P. ; Hall, A.C. ; Wurst, W. ; Arenas, E.
Wnt5a regulates ventral midbrain morphogenesis and the development of A9-A10 dopaminergic cells in vivo.Coolen, M. ; Bally-Cuif, L.
A microRNA as a gatekeeper of the midbrain-hindbrain boundary.Omodei, D. ; Acampora, D. ; Mancuso, P. ; Prakash, N. ; di Giovannantonio, L.G. ; Wurst, W. ; Simeone, A.
Anterior-posterior graded response to Otx2 controls proliferation and differentiation of dopaminergic progenitors in the ventral mesencephalon.Söker, T. ; Dalke, C. ; Puk, O. ; Floß, T. ; Becker, L. ; Bolle, I. ; Favor, J. ; Hans, W. ; Hölter, S.M. ; Horsch, M. ; Kallnik, M. ; Kling, E. ; Mörth, C. ; Schrewe, A. ; Stigloher, C. ; Topp, S. ; Gailus-Durner, V. ; Naton, B. ; Beckers, J. ; Fuchs, H. ; Ivandic, B. ; Klopstock, T. ; Schulz, S. ; Wolf, E. ; Wurst, W. ; Bally-Cuif, L. ; Hrabě de Angelis, M. ; Graw, J.
Pleiotropic effects in Eya3 knockout mice.Kronsbein, H.C. ; Jastorff, A.M. ; Maccarrone, G. ; Stalla, G. ; Wurst, W. ; Holsboer, F. ; Turck, C.W. ; Deussing, J.M.
CRHR1-dependent effects on protein expression and posttranslational modification in AtT-20 cells.Ninkovic, J. ; Stigloher, C. ; Lillesaar, C. ; Bally-Cuif, L.
Gsk3 beta/PKA and Gli1 regulate the maintenance of neural progenitors at the midbrain-hindbrain boundary in concert with E(Spl) factor activity.Mandillo, S. ; Tucci, V. ; Hölter, S.M. ; Meziane, H. ; Banchaabouchi, M.A. ; Kallnik, M. ; Lad, H.V. ; Nolan, P.M. ; Ouagazzal, A.M. ; Coghill, E.L. ; Gale, K. ; Golini, E. ; Jacquot, S. ; Krezel, W. ; Parker, A. ; Riet, F. ; Schneider, I. ; Marazziti, D. ; Auwerx, J. ; Brown, S.D. ; Chambon, P. ; Rosenthal, N. ; Tocchini-Valentini, G. ; Wurst, W.
Reliability, robustness, and reproducibility in mouse behavioral phenotyping: A cross-laboratory study.Norton, W.H.J. ; Folchert, A. ; Bally-Cuif, L.
Comparative analysis of serotonin receptor (HTR1A/HTR1B families) and transporter (slc6a4a/b) gene expression in the zebrafish brain.Blin, M. ; Norton, W.H.J. ; Bally-Cuif, L. ; Vernier, P.
NR4A2 controls the differentiation of selective dopaminergic nuclei in the zebrafish brain.Tripathi, P.P. ; di Giovannantonio, L.G. ; Viegi, A. ; Wurst, W. ; Simeone, A. ; Bozzi, Y.
Serotonin hyperinnervation abolishes seizure susceptibility in Otx2 conditional mutant mice.Lie, D.C. ; Götz, M.
Similarities and differences in stem cell fate, proliferation, migration, and differentiation in distinct forebrain regions.Lu, A. ; Steiner, M.A. ; Whittle, N. ; Vogl, A.M. ; Walser, S.M. ; Ableitner, M. ; Refojo, D. ; Ekker, M. ; Rubenstein, J.L. ; Stalla, G.K. ; Singewald, N. ; Holsboer, F. ; Wotjak, CT. ; Wurst, W. ; Deussing, J.M.
Conditional mouse mutants highlight mechanisms of corticotropin-releasing hormone effects on stress-coping behavior.Komisarczuk, A.Z. ; Topp, S. ; Stigloher, C. ; Kapsimali, M. ; Bally-Cuif, L. ; Becker, T.S.
Enhancer detection and developmental expression of zebrafish sprouty1, a member of the fgf8 synexpression group.Graw, J.
Cataract genetics.Jagasia, R. ; Lie, D.C.
Hippocampal neurogenic niche and regulation of adult neurogenesis.Lie, D.C. ; Götz, M.
Adult neurogenesis: Similarities and differences in stem cell fate, proliferation, migration, and differentiation in distinct forebrain regions.Lu, A. ; Steiner, M.A. ; Whittle, N. ; Vogl, A.M. ; Walser, S.M. ; Ableitner, M. ; Refojo, D. ; Ekker, M. ; Rubenstein, J.L. ; Stalla, G.K. ; Singewald, N. ; Holsboer, F. ; Wotjak, C.T. ; Wurst, W. ; Deussing, J.M.
Conditional CRH overexpressing mice: An animal model for stress-elicited pathologies and treatments that target the central CRH system.Kallnik, M.
Evaluation des modified hole boards als Primärscreen für mutante Mauslinien.Schmid, M.-T.
Comparative analyses of the function of alpha- and beta-catenin in cerebral cortical development.Oesterheld, M.
Analysis of biomolecular networks using a generic network analysis suite.di Benedetto, B.
The role of the ERK/MAPK pathway in the adult mouse brain for fear potentiated startle learning: a model to study fear-based anxiety disorders.Klafke, R.
Expression and functional analysis of the development of mesencephalic dopaminergic neurons in the chicken embryo.Rappl, A.-K.
Einfluss von HER2 auf EGF Rezeptor - vermittelte Signaltransduktion und Migration in humanen Glioblastomzelllinien.Rieger, S.
The regulation of neuronal progenitor cell migration by cell-cell adhesion factors during zebrafish cerebellar development.Stigloher, C.
Specification, maintenance and fate determination of neural progenitor pools in the zebrafish central nervous system.Weindl, K.
Cognitive phenotyping of wildtype and mutant mouse lines.Schmid, M.
Epitheliale-mesenchymale Transition (EMT) im Nierenzellkarzinom.Söker, T.
Untersuchungen zur funktionellen Charakterisierung des Eya3-Gens in Vertebraten.Klemm, S.
Functional role of Bcl10 and Malt1 in signal transduction from the FcεRI in mast cells and the LPA receptor in murine embryonic fibroblasts.Groß, O.
Generation and analysis of card9-deficient mice.Backes, S.
Vaccinia virus host range factor C7L plays an important regulatory role in the MVA life cycle.Ferch, U.
Analysis of B-cell antigen receptor-mediated NF-κ-B activation.Simonović, S.
Potentialities and division properties of adult neural stem cells in the zebrafish brain.Reschke, M.O.
Mitogen-inducible gene-6 is a negative regulator of the HER-family of receptor tyrosine kinases.Schweizer, M.
Chronic mild stress (CMS) in Mäusen Untersuchungen zu einem Tiermodell für Depression.Marwedel, A.L.
Characterisation of the binding properties of semaphorin-4 and plexin-B proteins.Floß, T.
Funktionelle Analyse des Mausgenoms durch Gene Trapping.Uez, N.
Der Transkriptionsfaktor Sall4 ist für die proximale-distale Musterbildung und die Elongation der posterioren Achse des Mausembryos erforderlich.Hüttl, R.E.
How to wire the nervous system - Neuropilin 1 in periphal circuit formation and a genomewide screen for novel axon guidance cues.Schumacher, M.
Characterization of CRH-R1 specific antibodies using cellular approaches and genetically modified mouse models.Bradke, F.
Intracellular mechanisms of axonal growth and regeneration.Jessberger, S. ; Aigner, S. ; Clemenson, G. ; Toni, N. ; Lie, D.C. ; Karalay, O. ; Overall, R. ; Kempermann, G. ; Gage, F.
Cdk5 regulates accurate maturation of newborn granule cells in the adult hippocampus.Chu, Y. ; Senghaas, N. ; Köster, R.W. ; Wurst, W. ; Kühn, R.
Novel caspase-suicide proteins for tamoxifen-inducible apoptosis.Delic, S. ; Streif, S. ; Deussing, J.M. ; Weber, P. ; Ueffing, M. ; Hölter, S.M. ; Wurst, W. ; Kühn, R.
Genetic mouse models for behavioral analysis through transgenic RNAi technology.Halbach, S. ; Vogt, S. ; Köhler, W. ; Felgenhauer, N. ; Welzl, G. ; Kremers, L. ; Zilker, T. ; Melchart, D.
Blood and urine mercury levels in adult amalgam patients of a randomized controlled trial: Interaction of Hg species in erythrocytes.Haupt, C. ; Huber, A.B.
How axons see their way - axonal guidance in the visual system.Winner, B. ; Rockenstein, E. ; Lie, D.C. ; Aigner, R. ; Mante, M. ; Bogdahn, U. ; Couillard-Despres, S. ; Masliah, E. ; Winkler, J.
Mutant alpha-synuclein exacerbates age-related decrease of neurogenesis.Faus-Kessler, T. ; Kirchner, M. ; Jakobi, G.
Modelling the decay of concentrations of nitrogenous compounds with distance from roads.Uez, N. ; Lickert, H. ; Kohlhase, J. ; Hrabě de Angelis, M. ; Kühn, R. ; Wurst, W. ; Floß, T.
Sall4 isoforms act during proximal-distal and anterior-posterior axis formation in the mouse embryo.Tsolakidou, A. ; Trümbach, D. ; Panhuysen, M. ; Pütz, B. ; Deussing, J.M. ; Wurst, W. ; Sillaber, I. ; Holsboer, F. ; Rein, T.
Acute stress regulation of neuroplasticity genes in mouse hippocampus CA3 area - possible novel signalling pathways.Bender, A. ; Beckers, J. ; Schneider, I. ; Hölter, S.M. ; Haack, T.B. ; Ruthsatz, T. ; Vogt Weisenhorn, D.M. ; Becker, L. ; Genius, J. ; Rujescu, D. ; Irmler, M. ; Mijalski, T. ; Mader, M.T. ; Quintanilla-Martinez, L. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Wurst, W. ; Schmid, J. ; Klopstock, T.
Creatine improves health and survival of mice.Schmidt, S.I. ; Gawlik, V. ; Hölter, S.M. ; Augustin, R. ; Scheepers, A. ; Behrens, M. ; Wurst, W. ; Gailus-Durner, V. ; Fuchs, H. ; Hrabě de Angelis, M. ; Kluge, R. ; Joost, H.G. ; Schürmann, A.
Deletion of glucose transporter GLUT8 in mice increases locomotor activity.Olbrich, M. ; Gerstner, E. ; Welzl, G. ; Fleischmann, F. ; Oßwald, W. ; Bahnweg, G. ; Ernst, D.
Quantification of mRNAs and housekeeping gene selection for quantitative real-time RT-PCR normalization in European beech (Fagus sylvatica L.) during abiotic and biotic stress.Stigloher, C. ; Chapouton, P. ; Adolf, B. ; Bally-Cuif, L.
Identification of neural progenitor pools by E(Spl) factors in the embryonic and adult brain.Topp, C. ; Stigloher, C. ; Komisarczuk, A.Z. ; Adolf, B. ; Becker, T.S. ; Bally-Cuif, L.
Fgf signaling in the zebrafish adult brain: Association of Fgf activity with ventricular zones but not cell proliferation.Leucht, C. ; Stigloher, C. ; Wizenmann, A. ; Klafke, R. ; Folchert, A. ; Bally-Cuif, L.
MicroRNA-9 directs late organizer activity of the midbrain-hindbrain boundary.Hölter, S.M. ; Dalke, C. ; Kallnik, M. ; Becker, L. ; Horsch, M. ; Schrewe, A. ; Favor, J. ; Klopstock, T. ; Beckers, J. ; Ivandic, B. ; Gailus-Durner, V. ; Fuchs, H. ; Hrabě de Angelis, M. ; Graw, J. ; Wurst, W.
'Sighted C3H' mice - a tool for analysing the influence of vision on mouse behaviour?Floß, T. ; Schnütgen, F.
Conditional gene trapping using the FLEx system.Puk, O. ; Dalke, C. ; Hrabě de Angelis, M. ; Graw, J.
Variation of the response to the optokinetic drum among various strains of mice.Ganguly, K. ; Favor, J. ; Neuhäuser-Klaus, A. ; Sandulache, R. ; Puk, O. ; Beckers, J. ; Horsch, M. ; Schädler, S. ; Vogt Weisenhorn, D.M. ; Wurst, W. ; Graw, J.
Novel allele of crybb2 in the mouse and its expression in the brain.Puk, O. ; Löster, J. ; Dalke, C. ; Soewarto, D. ; Fuchs, H. ; Budde, B. ; Nürnberg, P. ; Wolf, E. ; Hrabě de Angelis, M. ; Graw, J.
Mutation in a novel connexin-like gene (Gjf1) in the mouse affects early lens development and causes a variable small-eye phenotype.Schmidt, W. ; Klopp, N. ; Illig, T. ; Graw, J.
A novel GJA8 mutation causing a recessive triangular cataract.Hense, B.A. ; Jaser, W. ; Welzl, G. ; Pfister, G. ; Wöhler-Moorhoff, G.F. ; Schramm, K.-W.
Impact of 17alpha-ethinylestradiol on the plankton in freshwater microcosms-II: Responses of phytoplankton and the interrelation within the ecosystem.Schramm, K.-W. ; Jaser, W. ; Welzl, G. ; Pfister, G. ; Wöhler-Moorhoff, G.F. ; Hense, B.A.
Impact of 17alpha-ethinylestradiol on the plankton in freshwater microcosms-I: Response of zooplankton and abiotic variables.Michaelidis, T.M. ; Lie, D.C.
Wnt signaling and neural stem cells: Caught in the Wnt web.Volkmann, K. ; Rieger, S. ; Babaryka, A.N. ; Köster, R.W.
The zebrafish cerebellar rhombic lip is spatially patterned in producing granule cell populations of different functional compartments.Rieger, S. ; Volkmann, K. ; Köster, R.W.
Polysialyltransferase expression is linked to neuronal migration in the developing and adult zebrafish.Graw, J.
Nobelpreis 2007 in Medizin: Herstellung von knockout-Mäusen.Kühn, R. ; Wurst, W.
Genetisch veränderte Tiere.Duvezin-Caubet, S. ; Koppen, M. ; Wagener, J. ; Zick, M. ; Israel, L. ; Bernacchia, A. ; Jagasia, R. ; Rugarli, E.I. ; Imhof, A. ; Neupert, W. ; Langer, T. ; Reichert, A.S.
OPA1 processing reconstituted in yeast depends on the subunit composition of the m-AAA protease in mitochondria.Wurst, W. ; Kühn, R.
Genetisch veränderte Tiere.Adolf, B.
bHLH transcription factors and neurogenesis in the zebrafish late embryonic and adult central nervous system.Hitz, C.
The role of MAP-Kinases in anxiety and depression - studies with knockout and knockdown mouse models.Istvanffy, R.
The molecular and functional analysis of neurochondrin mouse mutant.Naserke, T.
Specific and redundant functions of Fgf receptors in development of the midbrain and anterior hindbrain of the mouse.Siewe, B.
Analysis of humanized antibody diversification in rabbits and mice using transgenic Immunoglobulin heavy chain (IgH) mini-loci.Storch, C.
Evaluation of COX-2 and P2RX7 as new targets for antidepressant drug development.Langwieser, N.N.
Molekulare und funktionelle Analyse des CACNA1C-Gens bei synaptischer Plastizität und dem Lernverhalten der Maus.