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Investigating a Fundamental Biological Process in Vaccinated Individuals

Featured Publication Computational Health ICB

When immune system killer cells detect signs of infection, some of them rapidly multiply, forming a large defensive force to fight the pathogen. However, this response does not occur in every killer cell. What determines whether a cell will proliferate or not? Researchers from Helmholtz Munich, Friedrich-Alexander University Erlangen-Nürnberg (FAU), and University Hospital Erlangen (UKER) have investigated this question.

Read more about this study in our news in German. 

Original Publication

Kocher et al., 2025: Quality of vaccination-induced T cell responses is conveyed by polyclonality and high, but not maximum, antigen receptor avidity. Science Immunology. DOI:10.1126/sciimmunol.adu6730 

 

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