Publications
Lorenz, S. ; Wahida, A. ; Bostock, M.J. ; Seibt, T. ; Santos Dias Mourão, A. ; Levkina, A. ; Trümbach, D. ; Soudy, M. ; Emler, D. ; Rothammer, N. ; Woo, M.S. ; Sonner, J.K. ; Novikova, M. ; Henkelmann, B. ; Aldrovandi, M. ; Kaemena, D.F. ; Mishima, E. ; Vermonden, P. ; Zong, Z. ; Cheng, D. ; Nakamura, T. ; Ito, J. ; Doll, S. ; Proneth, B. ; Bürkle, E. ; Rizzollo, F. ; Escamilla Ayala, A. ; Napolitano, V. ; Kolonko, M. ; Gaussmann, S. ; Merl-Pham, J. ; Hauck, S.M. ; Pertek, A. ; Orschmann, T. ; Van San, E. ; Vanden Berghe, T. ; Hass, D, ; Maida, A. ; Frenz, J.M. ; Pedrera, L. ; Dolga, A.M. ; Kraiger, M. ; Hrabě de Angelis, M. ; Fuchs, H. ; Ebert, G. ; Lenberg, J. ; Friedman, J. ; Scale, C. ; Agostinis, P. ; Zimprich, A. ; Vogt Weisenhorn, D.M. ; Garrett, L. ; Hölter, S.M. ; Wurst, W. ; Glaab, E. ; Lewerenz, J. ; Popper, B. ; Sieben, C. ; Steinacker, P. ; Zischka, H. ; García-Sáez, A.J. ; Tietze, A. ; Ramesh, S.K. ; Ayton, S. ; Vincendeau, M. ; Friese, M.A. ; Wigby, K. ; Sattler, M. ; Mann, M. ; Ingold, I. ; Jayavelu, A.K. ; Popowicz, G.M. ; Conrad, M.
A fin-loop-like structure in GPX4 underlies neuroprotection from ferroptosis.Li, D. ; Wettengel, J.M. ; Ajoyan, H. ; Ho, V. ; Wu, G. ; Bae, S. ; Zhang, H. ; Boldbaatar, D. ; George, J. ; Douglas, M.W. ; Tu, T.
Hepatitis B viral DNA integration occurs within three days of infection and is enhanced by ATR inhibition.Kaeuferle, T. ; Eiz-Vesper, B. ; Moosmann, A. ; Behrends, U. ; Decker, M. ; Gutjahr, L. ; Mautner, J. ; Klein, F. ; Kreer, C. ; Reger, M. ; Busch, D.H. ; D'Ippolito, E. ; Kohlmayer, F. ; Menzel, A. ; Willier, S. ; Maecker-Kolhoff, B. ; Feuchtinger, T.
Guiding antiviral cell therapy approaches with an online resource of clinically scored epitopes, T-cell receptors, and B-cell receptors.Murphy, J. ; Baran, M. ; Grünke, C. ; Haas, D. ; Barber, G.P. ; Pichlmair, A. ; Bowie, A.G.
Elongator is required for pattern recognition receptor and type I interferon signaling in macrophages.Kosinska, A. ; Kächele, M. ; Kerth, H.A. ; Mück-Häusl, M. ; Ates Öz, E. ; Gültan, M. ; Hansen-Palmus, L. ; Sacherl, J. ; Ko, C. ; Festag, J. ; Lehmann, M.H. ; Mogler, C. ; Steiger, K. ; Knolle, P.A. ; Bauer, T. ; Volz, A.K. ; Protzer, U.
MVA-HBVac-A novel vaccine vector that allows pan-genotypic targeting of hepatitis B virus by therapeutic vaccination.Wu, X. ; Quan, D. ; Li, W. ; Wisskirchen, K. ; Wu, W. ; Zhou, Y. ; Liu, Y.P. ; Wan, X. ; Wang, X. ; Zhang, X. ; Yang, L. ; Zheng, M. ; Zhang, K. ; Protzer, U. ; Du, S. ; Qu, X.
Clinical results of an HBV-specific T-cell receptor-T-cell therapy (SCG101) in patients with HBV-related hepatocellular carcinoma treated in an investigator-initiated, interventional trial.Hammer, E. ; Flynn, C. ; Rössler, J. ; Erder, J. ; Napieralski, R. ; Fricke, L. ; Campbell, B. ; Feuerherd, M. ; Esslinger, F. ; von Brunn, A. ; Weber, T. ; King, S. ; Tan, S. ; Brisson, A.R. ; Protzer, U. ; Schricker, G. ; Gärtner, K. ; Ebert, G. ; Moretti, A. ; Klein, F. ; Knoops, K. ; Heeren, R. ; Hammerschmidt, W. ; Zeidler, R. ; Wilhelm, O. ; Knolle, P.A. ; Höchst, B.
Prediction of COVID-19 disease progression by multiparametric analysis of circulating extracellular vesicles with flow cytometry.An, Y. ; Bergant, V. ; Grünke, C. ; Bonnal, B. ; Henrici, A. ; Pichlmair, A. ; Schubert, B. ; Marsico, A.
TransFactor-Prediction of pro-viral SARS-CoV-2 host factors using a protein language model.Hoheisel, F. ; Fleischer, K.M. ; Rubarth, K. ; Sepúlveda, N. ; Bauer, S. ; Konietschke, F. ; Kedor Peters, C. ; Stein, A.E. ; Wittke, K. ; Seifert, M. ; Bellmann-Strobl, J. ; Mautner, J. ; Behrends, U. ; Scheibenbogen, C. ; Sotzny, F.
Exploratory study on autoantibodies to arginine-rich human peptides mimicking Epstein-Barr virus in women with post-COVID and myalgic encephalomyelitis/chronic fatigue syndrome.Appelman, M.D. ; Nguyen, T.A. ; Oswald, A. ; Lucko, A.M. ; Paulusma, C.C. ; Protzer, U. ; van de Graaf, S.F.J.
NTCP ubiquitination enables HBV infection.Dehn, S. ; Burkhard, R. ; Leyens, J. ; Kaiser, T. ; Brandimarte, S. ; Heiligensetzer, D. ; Koppensteiner, H. ; Bajoghli, B. ; Hailfinger, S. ; Schilbach, K. ; Schindler, M.
HIV-1 manipulates CD96 on CD4+ T cells to subvert antiviral immunity.Yin, C. ; Fedorov, A. ; Guo, H. ; Crawford, J.C. ; Rousseau, C. ; Zhong, X. ; Williams, R.M. ; Gautam, A.K. ; Koehler, H.S. ; Whisnant, A.W. ; Hennig, T. ; Rozina, A. ; Zhong, Y. ; Lv, S. ; Bergant, V. ; Wang, S. ; Dröge, P. ; Miller, S. ; Poptsova, M. ; Rehwinkel, J. ; Pichlmair, A. ; Mocarski, E.S. ; Thomas, P.G. ; Dölken, L. ; Zhang, T. ; Herbert, A. ; Balachandran, S.
Host cell Z-RNAs activate ZBP1 during virus infections.Läderach, F. ; Piteros, I. ; Fennell, E. ; Bremer, E. ; Last, M. ; Schmid, S. ; Rieble, L. ; Campbell, C.D. ; Ludwig-Portugall, I. ; Bornemann, L. ; Gruhl, A. ; Eulitz, K. ; Gueguen, P. ; Mietz, J. ; Müller, A. ; Pezzino, G. ; Schmitz, J. ; Ferlazzo, G. ; Mautner, J. ; Münz, C.
EBV induces CNS homing of B cells attracting inflammatory T cells.Özer, S. ; Strobelt, R. ; Kosinska, A. ; Frishman, G. ; Wettengel, J.M. ; Pleninger, L. ; Körber, N. ; Liang, W. ; Ates Öz, E. ; Zuniga, M. ; Bauer, T. ; Ebert, G. ; Protzer, U. ; Vincendeau, M.
HERV-K10 as a mediator of immune modulation in hepatitis infections.Rupp, M. ; Ferry, T. ; Khan Mirzaei, M. ; Alt, V. ; Deng, L. ; Walter, N.
Bakteriophagen zur Behandlung muskuloskelettaler Infektionen – Eine Übersicht zu klinischem Einsatz, offenen Fragen und rechtlichem Rahmen.Girault, V. ; Stukalov, A. ; Carter-Timofte, M.E. ; Hertzog, J. ; Verin, M. ; Austen, K. ; Haas, D.A. ; Oubraham, L. ; Piras, A. ; Maidl, S. ; Öllinger, R. ; Rad, R. ; Protzer, U. ; Kaufer, B.B. ; Lebbink, R.J. ; Rehwinkel, J. ; Mogensen, T.H. ; Pichlmair, A.
Multi-proteomic profiling of the varicella-zoster virus-host interface reveals host susceptibilities to severe infection.Al-Ameer, H.J. ; Zihlif, M. ; Maslat, A. ; Al-Awaida, W.J. ; Ayyash, A.M. ; Imraish, A. ; Al-Qinna, N. ; Al-Omari, T. ; Al-Qaisi, T. ; Al-Zyoud, W. ; Alzubi, B.T. ; Atoom, A.M. ; Fattash, I.A. ; Ambike, S. ; Goh, K.W. ; Gushchina, Y.S.
Targeting the proliferation of glioblastoma cells and enhancement of doxorubicin and temozolomide cytotoxicity through inhibition of PFKFB4 and HMOX1 genes with siRNAs.Kennedy, P.T. ; Allweiss, L. ; Bertoletti, A. ; Cornberg, M. ; Gehring, A.J. ; Guidotti, L.G. ; Kerth, H.A. ; Lemoine, M. ; Levrero, M. ; Lim, S.G. ; Tavis, J.E. ; Testoni, B. ; Tu, T.
Scientific and medical evidence informing expansion of hepatitis B treatment guidelines.Gemünd, I. ; Bonaguro, L. ; Becker, M. ; Müller, S. ; Joos, C. ; De Domenico, E. ; Aschenbrenner, A.C. ; Schultze, J.L. ; Moosmann, A. ; Beyer, M.D.
Characterization of human CMV-specific CD8+ T cells using multi-layer single-cell omics.Mautner, J. ; Middeldorp, J.M.
Epstein-Barr Virus (EBV)-Specific Humoral Immune Responses in Health and Disease.Jaeckel, E. ; Friedman, S.L. ; Hudecek, M. ; Protzer, U.
Chimeric antigen receptor (CAR) T-cell therapy: Engineering immune cells to treat liver diseases.Büttner, F.A. ; Grünwald, V. ; Nößner, E. ; Tsaur, I. ; Bedke, J. ; Schwab, M. ; Schaeffeler, E.
Abstract 7155: A PD-L1-independent phenotype uncovers responders to combined therapy with immune checkpoint inhibitors in kidney cancer.Lammi, V. ; Nakanishi, T. ; Jones, S.E. ; Andrews, S.J. ; Karjalainen, J. ; Cortes, B. ; O'Brien, H.E. ; Ochoa-Guzman, A. ; Fulton-Howard, B.E. ; Broberg, M. ; Haapaniemi, H.H. ; Kanai, M. ; Pirinen, M. ; Schmidt, A. ; Mitchell, R.E. ; Mousas, A. ; Mangino, M. ; Huerta-Chagoya, A. ; Sinnott-Armstrong, N. ; Cirulli, E.T. ; Vaudel, M. ; Kwong, A.S.F. ; Maiti, A.K. ; Marttila, M.M. ; Posner, D.C. ; Rodriguez, A.A. ; Batini, C. ; Minnai, F. ; Dearman, A.R. ; Warmerdam, C.A.R. ; Sequeros, C.B. ; Winkler, T.W. ; Jordan, D.M. ; Rešcenko, R. ; Miano, L. ; Lane, J.M. ; Chung, R.K. ; Guillen-Guio, B. ; Leavy, O.C. ; Carvajal-Silva, L. ; Aguilar-Valdés, K. ; Frangione, E. ; Guare, L.A. ; Vergasova, E. ; Marouli, E. ; Striano, P. ; Zainulabid, U.A. ; Kumar, A. ; Ahmad, H.F. ; Edahiro, R. ; Azekawa, S. ; Luoh, S.W. ; Erikstrup, C. ; Pedersen, O.B.V. ; Lerner-Ellis, J. ; Colombo, A. ; Grzymski, J.J. ; Ishii, M. ; Okada, Y. ; Beckmann, N.D. ; Kumari, M. ; Wagner, R. ; Heid, I.M. ; John, C. ; Short, P.J. ; Magnus, P. ; Ansone, L. ; Valenti, L.V.C. ; Lee, S.A. ; Wain, L.V. ; Verdugo, R.A. ; Banasik, K. ; Geller, F. ; Franke, L.H. ; Rakitko, A. ; Duncan, E.L. ; Renieri, A. ; Tsilidis, K.K. ; de Cid, R. ; Niavarani, A. ; Abner, E. ; Tusié-Luna, T. ; Verma, S.S. ; Smith, G.D. ; Timpson, N.J. ; Madduri, R.K. ; Cho, K. ; Daly, M.J. ; Ganna, A. ; Schulte, E.C. ; Richards, J.B. ; Ludwig, K.U. ; Marks-Hultström, M. ; Zeberg, H. ; Ollila, H.M.
Genome-wide association study of long COVID.Nguyen Tien, D. ; Thi Thu Bui, H. ; Hoang Thi Ngoc, T. ; Thi Pham, T. ; Trung Nguyen, D. ; Nguyen Thi Thu, H. ; Thu Hang Vu, T. ; Lan Anh Luong, T. ; Thu Hoang, L. ; Cam Tu, H. ; Körber, N. ; Bauer, T. ; Khanh Ho, L.
A data-driven approach to assessing hepatitis B mother-to-child transmission risk prediction model: Machine learning perspective.Merold, V. ; Bekere, I. ; Kretschmer, S. ; Schnell, A.F. ; Kmiec, D. ; Sivarajan, R. ; Lammens, K. ; Liu, R. ; Mergner, J. ; Teppert, J. ; Hirschenberger, M. ; Henrici, A. ; Hammes, S. ; Buder, K. ; Weitz, M. ; Hackmann, K. ; Koenig, L.M. ; Pichlmair, A. ; Schwierz, N. ; Sparrer, K.M.J. ; Lee-Kirsch, M.A. ; de Oliveira Mann, C.C.
Structural basis for OAS2 regulation and its antiviral function.Stoleriu, M.-G. ; Ansari, M. ; Strunz, M. ; Schamberger, A.C. ; Heydarian, M. ; Gabriel, C. ; Najak, A. ; Disovic, A. ; Schneider, J. ; Gerckens, M. ; Burgstaller, G. ; Ding, Y. ; Doryab, A. ; Voss, C. ; Ketscher, C. ; Sienel, W. ; Kauke, T. ; Fertmann, J. ; Schneider, C. ; Behr, J. ; Irmler, M. ; Beckers, J. ; Eickelberg, O. ; Schubert, B. ; Hauck, S.M. ; Hatz, R. ; Schmid, O. ; Stöger, T. ; Schiller, H. ; Hilgendorff, A.
Development of advanced in-vitro human bronchial epithelial models and lung cell atlas in COPD enabled by thoracic surgery translational research.Ahmadi, A. ; Shokoohizadeh, L. ; Sheikhesmaili, F. ; Mirzaei, M.K. ; Mohammadi, A. ; Nikkhoo, B. ; Khodaei, H. ; Alikhani, M.Y. ; Yousefimashouf, R.
Gut microbiomes and treatment-resistant ulcerative colitis: A case-control study using qPCR.Huang, W. ; Khan Mirzaei, M. ; Deng, L.
Comparative evaluation of long-term preservation methods for morphologically distinct bacteriophages.Hofer, T.P. ; Nieto, A.E. ; Käsmann, L. ; Pelikan, C. ; Taugner, J. ; Mathur, S. ; Eze, C. ; Belka, C. ; Manapov, F. ; Nößner, E.
Early recovery of leukocyte subsets is associated with favorable progression-free survival in patients with inoperable stage II/III NSCLC after multimodal treatment: A prospective explorative study.Wu, J. ; Liu, Y. ; Su, J. ; Yang, Y. ; Deng, H. ; Yanglan, M. ; Wu, X. ; Luo, S. ; Liao, Y. ; Wang, L.
Investigation on Klebsiella pneumoniae in the field of extracellular vesicles.Chen, W.L. ; Chang, Y.L. ; Lin, S.F. ; Protzer, U. ; Isogawa, M. ; Yang, H.C. ; Huang, L.R.
Differential regulation of calcium-NFAT signaling pathway by Akt isoforms: Unraveling effector dynamics and exhaustion of cytotoxic T lymphocytes in tumor microenvironment.Luo, J. ; Molbay, M. ; Chen, Y. ; Horvath, I. ; Kadletz, K. ; Kick, B. ; Zhao, S. ; Al-Maskari, R. ; Singh, I. ; Ali, M. ; Bhatia, H.S. ; Minde, D.-P. ; Negwer, M. ; Höher, L. ; Calandra, G.M. ; Groschup, B. ; Su, J. ; Kimna, C. ; Rong, Z. ; Galensowske, N. ; Todorov, M.I. ; Jeridi, D. ; Ohn, T.-L. ; Roth, S. ; Simats, A. ; Singh, V. ; Khalin, I. ; Pan, C. ; Arus, B.A. ; Bruns, O.T. ; Zeidler, R. ; Liesz, A. ; Protzer, U. ; Plesnila, N. ; Ussar, S. ; Hellal, F. ; Paetzold, J.C. ; Elsner, M. ; Dietz, H. ; Ertürk, A.
Nanocarrier imaging at single-cell resolution across entire mouse bodies with deep learning.Yang, Q. ; Sun, J. ; Wang, X. ; Wang, J. ; Liu, Q. ; Ru, J. ; Zhang, X. ; Wang, S. ; Hao, R. ; Bian, P. ; Dai, X. ; Gong, M. ; Zhang, Z. ; Wang, A. ; Bai, F. ; Li, R. ; Cai, Y. ; Jiang, Y.
SVLearn: A dual-reference machine learning approach enables accurate cross-species genotyping of structural variants.Ahmadi, A. ; Yousefimashouf, R. ; Mohammadi, A. ; Nikkhoo, B. ; Shokoohizadeh, L. ; Khan Mirzaei, M. ; Alikhani, M.Y. ; Sheikhesmaili, F. ; Khodaei, H.
Investigating the expression of anti/pro-inflammatory cytokines in the pathogenesis and treatment of ulcerative colitis and its association with serum level of vitamin D.Chen, F. ; Wettengel, J.M. ; Gegenfurtner, F. ; Moosmüller, J. ; Bunse, T. ; Jeske, S. ; Hagen, P. ; Ni, Y. ; Urban, S. ; Protzer, U.
Identification of NTCP animal orthologs supporting hepatitis B virus binding and infection.Liao, Y. ; Liu, Y. ; Li, D. ; Luo, S. ; Huang, Y. ; Wu, J. ; Su, J. ; Yang, Y. ; Zhu, Z. ; Yanglan, M. ; Deng, H. ; Wu, X. ; Xu, J. ; Cao, F. ; Cai, C. ; Li, Z. ; Yang, R. ; Deng, X. ; Wei, J. ; Wang, L.
COVID-19 patient serum-derived extracellular vesicles deliver miR-20b-5p induces neutrophil extracellular traps.Rust, L.N. ; Wettengel, J.M. ; Biswas, S. ; Ryu, J. ; Piekarski, N. ; Yusova, S. ; Lutz, S.S. ; Naldiga, S. ; Hinrichs, B.J. ; Sullivan, M.N. ; Lo, J.O. ; Protzer, U. ; Smedley, J.V. ; Sacha, J.B. ; Hanna, C.B. ; Bimber, B.N. ; Hennebold, J.D. ; Burwitz, B.J.
Liver-specific transgenic expression of human NTCP in rhesus macaques confers HBV susceptibility on primary hepatocytes.Luzius, T. ; Jeske, S. ; Baer, J. ; Goelnitz, U. ; Protzer, U. ; Wettengel, J.M.
A multiplex polymerase chain reaction assay for the detection of herpes simplex virus, cytomegalovirus, and varicella-zoster virus in cerebrospinal Fluid.Rothfuß, C. ; Baumann, T. ; Donakonda, S. ; Brauchle, B. ; Marcinek, A. ; Urban, C. ; Mergner, J. ; Pedde, A.M. ; Hirschberger, A. ; Krupka, C. ; Neumann, A.S. ; Hänel, G. ; Merten, C. ; Öllinger, R. ; Hecker, J.S. ; Bauer, T. ; Schmid, C.R. ; Götze, K.S. ; Altomonte, J. ; Bücklein, V.L. ; Jacobs, R. ; Rad, R. ; Dawid, C. ; Simeoni, L. ; Schraven, B. ; Pichlmair, A. ; Subklewe, M. ; Knolle, P.A. ; Böttcher, J.P. ; Höchst, B.
Two-layered immune escape in AML is overcome by Fcγ receptor activation and inhibition of PGE2 signaling in NK cells.Ko, C. ; Cheng, C.-C. ; Mistretta, D. ; Ambike, S. ; Sacherl, J. ; Velkov, S. ; Liao, B.-H. ; Bester, R. ; Gültan, M. ; Polezhaeva, O. ; Herrmann, A. ; Jakwerth, C.A. ; Schmidt-Weber, C.B. ; Bugert, J.J. ; Wölfel, R. ; Grass, V. ; Essbauer, S. ; Schnepf, D. ; Keppler, O.T. ; Vondran, F.W.R. ; Pichlmair, A. ; Mogler, C. ; Ebert, G. ; Protzer, U.
SARS-CoV-2 productively infects human hepatocytes and induces cell death.Li, D. ; Ho, V. ; Teng, C.F. ; Tsai, H.W. ; Liu, Y. ; Bae, S. ; Ajoyan, H. ; Wettengel, J.M. ; Protzer, U. ; Gloss, B.S. ; Rockett, R.J. ; Asady, R.A. ; Li, J. ; So, S. ; George, J. ; Douglas, M.W. ; Tu, T.
Novel digital droplet inverse PCR assay shows that natural clearance of Hepatitis B infection is associated with fewer viral integrations.Jeske, S. ; Wettengel, J.M. ; Gegenfurtner, F. ; Fischer, K. ; Moosmüller, J. ; Chakraborty, A. ; Ko, C. ; Burwitz, B.J. ; Schnieke, A. ; Protzer, U.
Identification of amino acids restricting HBV receptor function in porcine NTCP.Schmidt, A. ; Casadei, N. ; Brand, F. ; Demidov, G. ; Vojgani, E. ; Abolhassani, A. ; Aldisi, R. ; Butler-Laporte, G. ; Alawathurage, T.M. ; Augustin, M. ; Bals, R. ; Bellinghausen, C. ; Berger, M.M. ; Bitzer, M. ; Bode, C. ; Boos, J. ; Brenner, T. ; Cornely, O.A. ; Eggermann, T. ; Erber, J. ; Feldt, T. ; Fuchsberger, C. ; Gagneur, J. ; Göpel, S. ; Haack, T. ; Häberle, H. ; Hanses, F. ; Heggemann, J. ; Hehr, U. ; Hellmuth, J.C. ; Herr, C. ; Hinney, A. ; Hoffmann, P. ; Illig, T. ; Jensen, B.O. ; Keitel, V. ; Kim-Hellmuth, S. ; Koehler, P. ; Kurth, I. ; Lanz, A.L. ; Latz, E. ; Lehmann, C. ; Luedde, T. ; Maj, C. ; Mian, M. ; Miller, A. ; Muenchhoff, M. ; Pink, I. ; Protzer, U. ; Rohn, H. ; Rybniker, J. ; Scaggiante, F. ; Schaffeldt, A. ; Scherer, C. ; Schieck, M. ; Schmidt, S.V. ; Schommers, P. ; Spinner, C.D. ; Vehreschild, M.J.G.T. ; Velavan, T.P. ; Volland, S. ; Wilfling, S. ; Winter, C. ; Richards, J.B. ; Heimbach, A. ; Becker, K. ; Ossowski, S. ; Schultze, J.L. ; Nürnberg, P. ; Nöthen, M.M. ; Motameny, S. ; Nothnagel, M. ; Riess, O. ; Schulte, E.C. ; Ludwig, K.U.
Systematic assessment of COVID-19 host genetics using whole genome sequencing data.Liang, W. ; Stubbe, M. ; Pleninger, L. ; Hofferek, A. ; Stubbe, H.C. ; Mai, J. ; Özer, S. ; Frishman, D. ; Schreiner, S. ; Vincendeau, M.
HERV reactivation by adenovirus infection is associated with viral immune regulation.Ahmadi, A. ; Shokoohizadeh, L. ; Sheikhesmaili, F. ; Nikkhoo, B. ; Mohammadi, A. ; Mirzaei, M.K. ; Alikhani, M.Y. ; Yousefimashouf, R.
The role of vitamin D in treated and refractory ulcerative colitis patients: A case-control study.Rong, Z. ; Mai, H. ; Ebert, G. ; Kapoor, S. ; Puelles, V.G. ; Czogalla, J. ; Hu, S. ; Su, J. ; Prtvar, D. ; Singh, I. ; Schädler, J. ; Delbridge, C. ; Steinke, H. ; Frenzel, H. ; Schmidt, K. ; Braun, C. ; Bruch, G. ; Ruf, V. ; Ali, M. ; Sühs, K.W. ; Nemati, M. ; Hopfner, F. ; Ulukaya, S. ; Jeridi, D. ; Mistretta, D. ; Caliskan, Ö.S. ; Wettengel, J.M. ; Cherif, F. ; Kolabas, Z.I. ; Molbay, M. ; Horvath, I. ; Zhao, S. ; Krahmer, N. ; Yildirim, A.Ö. ; Ussar, S. ; Herms, J. ; Huber, T.B. ; Tahirovic, S. ; Schwarzmaier, S.M. ; Plesnila, N. ; Höglinger, G. ; Ondruschka, B. ; Bechmann, I. ; Protzer, U. ; Elsner, M. ; Bhatia, H.S. ; Hellal, F. ; Ertürk, A.
Persistence of spike protein at the skull-meninges-brain axis may contribute to the neurological sequelae of COVID-19.Einhauser, S. ; Asam, C. ; Weps, M. ; Senninger, A. ; Peterhoff, D. ; Bauernfeind, S. ; Asbach, B. ; Carnell, G.W. ; Heeney, J.L. ; Wytopil, M. ; Fuchs, A. ; Messmann, H. ; Prelog, M. ; Liese, J. ; Jeske, S.D. ; Protzer, U. ; Hoelscher, M. ; Geldmacher, C. ; Überla, K. ; Steininger, P. ; Wagner, R.
Longitudinal effects of SARS-CoV-2 breakthrough infection on imprinting of neutralizing antibody responses.Wang, R. ; Hu, M. ; Lozzi, I. ; Jin, C.Z.J. ; Ma, D. ; Splith, K. ; Mengwasser, J. ; Wolf, V. ; Feldbrügge, L. ; Tang, P. ; Timmermann, L. ; Hillebrandt, K.H. ; Kirchner, M. ; Mertins, P. ; Hilfenhaus, G. ; Neumann, C.C.M. ; Kammertoens, T. ; Pratschke, J. ; Malinka, T. ; Sauer, I.M. ; Nößner, E. ; Guo, Z.S. ; Felsenstein, M.
Cytokine-armed vaccinia virus promotes cytotoxicity toward pancreatic carcinoma cells via activation of human intermediary CD56dimCD16dim natural killer cells.Orabi, A. ; Shameli, K. ; Protzer, U. ; Moeini, H.
Adenoviral fiber-knob based vaccination elicits efficient neutralizing antibodies and T cell responses against adenovirus infection.Wang, Y. ; Rambold, U. ; Fiedler, P. ; Babushku, T. ; Tapken, C.L. ; Hoefig, K.P. ; Hofer, T.P. ; Adler, H. ; Yildirim, A.Ö. ; Strobl, L.J. ; Zimber-Strobl, U.
CD30 influences germinal center B-cell dynamics and the expansion of IgG1-switched B cells.Huang, Y. ; Urban, C. ; Hubel, P. ; Stukalov, A. ; Pichlmair, A.
Protein turnover regulation is critical for influenza A virus infection.Maxwell, M. ; Yan, D. ; Rivest, B. ; Boone, A. ; Cardia, J. ; Nößner, E.
INTASYL self-delivering RNAi decreases TIGIT expression, enhancing NK cell cytotoxicity: A potential application to increase the efficacy of NK adoptive cell therapy against cancer.Ringelhan, M. ; Schuehle, S. ; van de Klundert, M. ; Kotsiliti, E. ; Plissonnier, M.L. ; Faure-Dupuy, S. ; Riedl, T. ; Lange, S. ; Wisskirchen, K. ; Thiele, F. ; Cheng, C.-C. ; Yuan, D.T. ; Leone, V. ; Schmidt, R. ; Hünergard, J. ; Geisler, F. ; Unger, K. ; Algül, H. ; Schmid, R.M. ; Rad, R. ; Wedemeyer, H. ; Levrero, M. ; Protzer, U. ; Heikenwälder, M.
HBV-related HCC development in mice is STAT3 dependent and indicates an oncogenic effect of HBx.Lau, D.T.Y. ; Jackson, K. ; Picchio, C.A. ; Kramvis, A. ; Sonderup, M. ; Lemoine, M. ; Matthews, G. ; Howell, J. ; Coffin, C.S. ; Hellard, M. ; Lee, A.U. ; Anderson, D.A. ; Kerth, H.A. ; Lee, E.E. ; Tavis, J.E. ; Dandri, M. ; Revill, P.A. ; Spearman, C.W. ; Penicaud, C. ; Levrero, M. ; El-Sayed, M.
Availability of point-of-care HBV tests in resource-limited settings.Du, S. ; Wisskirchen, K. ; Zhang, K. ; Protzer, U.
Correspondence on Editorial regarding "Genetically modified, redirected T cells target hepatitis B surface antigen-positive hepatocytes and hepatocellular carcinoma lesions in a clinical setting".Samieipour, Y. ; Wiegand, M. ; Willner, E.M. ; Hoffmann, D. ; Shameli, K. ; Protzer, U. ; Moeini, H.
Replication-deficient sendai virus expressing human norovirus capsid protein elicits robust NoV-specific antibody and T-cell responses in mice.Wagner, L. ; Schneider, H. ; Luppa, P.B. ; Schröder, K. ; Wantia, N. ; Querbach, C. ; Jeske, S. ; Lahmer, T. ; Rothe, K. ; Dibos, M. ; Voit, F. ; Erber, J. ; Spinner, C.D. ; Schneider, J. ; Triebelhorn, J.
Evaluation of a host-protein signature score for differentiating between bacterial and viral infections: Real-life evidence from a German tertiary hospital.Enriquez, G.F. ; Macchiaverna, N.P. ; Garbossa, G. ; Quebrada Palacio, L.P. ; Ojeda, B.L. ; Bua, J. ; Gaspe, M.S. ; Cimino, R. ; Gürtler, R.E. ; Postan, M. ; Cardinal, M.V.
Humans seropositive for Trypanosoma cruzi co-infected with intestinal helminths have higher infectiousness, parasitaemia and Th2-type response in the Argentine Chaco.Huang, Y. ; Bergant, V. ; Grass, V. ; Emslander, Q. ; Hamad, M.S. ; Hubel, P. ; Mergner, J. ; Piras, A. ; Krey, K. ; Henrici, A. ; Öllinger, R. ; Tesfamariam, Y.M. ; Dalla Rosa, I. ; Bunse, T. ; Sutter, G. ; Ebert, G. ; Schmidt, F.I. ; Way, M. ; Rad, R. ; Bowie, A.G. ; Protzer, U. ; Pichlmair, A.
Multi-omics characterization of the monkeypox virus infection.Saxena, A. ; Mautner, J.
A disease hidden in plain sight: Pathways and mechanisms of neurological complications of post-acute sequelae of COVID-19 (NC-PASC).Tschuck, J. ; Padmanabhan Nair, V. ; Galhoz, A. ; Zaratiegui, C. ; Tai, H.-M. ; Ciceri, G. ; Rothenaigner, I. ; Tchieu, J. ; Stockwell, B.R. ; Studer, L. ; Cabianca, D.S. ; Menden, M.P. ; Vincendeau, M. ; Hadian, K.
Suppression of ferroptosis by vitamin A or radical-trapping antioxidants is essential for neuronal development.Bunse, T. ; Ziel, A. ; Hagen, P. ; Rigopoulos, G. ; Yasar, U. ; Inan, H. ; Köse, G. ; Eigner, U. ; Kaiser, R. ; Bardeck, N. ; Köffer, J. ; Kolb, M. ; Ren, X. ; Tan, D. ; Dai, L. ; Protzer, U. ; Wettengel, J.M.
Analytical and clinical evaluation of a novel real-time PCR-based detection kit for Mpox virus.Xie, Z. ; Protzer, U.
Activating adaptive immunity by bispecific, T-cell engager antibodies bridging infected and immune-effector cells is a promising novel therapy for chronic hepatitis B.Schiller, L. ; Ko, C. ; Kosinska, A. ; Grimm, D. ; Protzer, U.
Production and Purification of Adeno-Associated Viral Vectors for the Development of Immune-Competent Mouse Models of Persistent Hepatitis B Virus Replication.Zhang, B. ; Mautner, J. ; Münz, C.
Editorial: EBV-induced T cell immunity in cancers.Wang, Z. ; Peng, X. ; Hülpüsch, C. ; Khan Mirzaei, M. ; Reiger, M. ; Traidl-Hoffmann, C. ; Deng, L. ; Schloter, M.
Distinct prophage gene profiles of Staphylococcus aureus strains from atopic dermatitis patients and healthy individuals.Sai, M. ; Hank, E.C. ; Tai, H.-M. ; Kasch, T. ; Lewandowski, M. ; Vincendeau, M. ; Marschner, J.A. ; Merk, D.J.
Development of Nurr1 agonists from amodiaquine by scaffold hopping and fragment growing.Tamalunas, A. ; Wendt, A. ; Springer, F. ; Vigodski, V. ; Trieb, M. ; Eitelberger, N. ; Poth, H. ; Ciotkowska, A. ; Rutz, B. ; Hu, S. ; Schulz, H. ; Ledderose, S. ; Rogenhofer, N. ; Kolben, T. ; Nößner, E. ; Stief, C.G. ; Hennenberg, M.
Immunomodulatory imide drugs inhibit human detrusor smooth muscle contraction and growth of human detrusor smooth muscle cells, and exhibit vaso-regulatory functions.Fischer, F. ; Mücke, J. ; Werny, L. ; Gerrer, K. ; Mihatsch, L. ; Zehetmaier, S. ; Riedel, I. ; Geisperger, J. ; Bodenhausen, M. ; Schulte-Hillen, L. ; Hoffmann, D. ; Protzer, U. ; Mautner, J. ; Behrends, U. ; Bauer, T. ; Körber, N.
Evaluation of novel Epstein-Barr virus-derived antigen formulations for monitoring virus-specific T cells in pediatric patients with infectious mononucleosis.Bosch, M. ; Kallin, N. ; Donakonda, S. ; Zhang, J.D. ; Wintersteller, H. ; Hegenbarth, S. ; Heim, K. ; Ramirez, C. ; Fürst, A. ; Lattouf, E.I. ; Feuerherd, M. ; Chattopadhyay, S. ; Kumpesa, N. ; Griesser, V. ; Hoflack, J.C. ; Siebourg-Polster, J. ; Mogler, C. ; Swadling, L. ; Pallett, L.J. ; Meiser, P. ; Manske, K. ; de Almeida, G.P. ; Kosinska, A. ; Sandu, I. ; Schneider, A. ; Steinbacher, V. ; Teng, Y. ; Schnabel, J.A. ; Theis, F. ; Gehring, A.J. ; Boonstra, A. ; Janssen, H.L.A. ; Vandenbosch, M. ; Cuypers, E. ; Öllinger, R. ; Engleitner, T. ; Rad, R. ; Steiger, K. ; Oxenius, A. ; Lo, W.L. ; Klepsch, V. ; Baier, G. ; Holzmann, B. ; Maini, M.K. ; Heeren, R. ; Murray, P.J. ; Thimme, R. ; Herrmann, C. ; Protzer, U. ; Böttcher, J.P. ; Zehn, D. ; Wohlleber, D. ; Lauer, G.M. ; Hofmann, M. ; Luangsay, S. ; Knolle, P.A.
A liver immune rheostat regulates CD8 T cell immunity in chronic HBV infection.Kupke, P. ; Brucker, J. ; Wettengel, J.M. ; Protzer, U. ; Wenzel, J.J. ; Schlitt, H.J. ; Geissler, E.K. ; Werner, J.M.
Cytokine response of natural killer cells to Hepatitis B virus infection depends on monocyte co-stimulation.Wan, X. ; Wisskirchen, K. ; Jin, T. ; Yang, L. ; Wang, X. ; Wu, X. ; Liu, F. ; Wu, Y. ; Ma, C. ; Pang, Y. ; Li, Q. ; Zhang, K. ; Protzer, U. ; Du, S.
Genetically redirected HBV-specific T cells target HBsAg-positive hepatocytes and primary lesions in HBV-associated HCC.Kohantorabi, M. ; Ugolotti, A. ; Sochor, B. ; Rössler, J. ; Wagstaffe, M. ; Meinhardt, A. ; Beck, E.E. ; Dolling, D.S. ; Garcia, M.B. ; Creutzburg, M. ; Keller, T.F. ; Schwartzkopf, M. ; Vayalil, S.K. ; Thuenauer, R. ; Guédez, G. ; Löw, C. ; Ebert, G. ; Protzer, U. ; Hammerschmidt, W. ; Zeidler, R. ; Roth, S.V. ; Di Valentin, C. ; Stierle, A. ; Noei, H.
Light-induced transformation of virus-like particles on TiO2.Almanzar, G. ; Koosha, K. ; Vogt, T. ; Stein, A. ; Ziegler, L. ; Asam, C. ; Weps, M. ; Schwägerl, V. ; Richter, L. ; Hepp, N. ; Fuchs, A. ; Wagenhäuser, I. ; Reusch, J. ; Krone, M. ; Geldmacher, C. ; Protzer, U. ; Steininger, P. ; Überla, K. ; Wagner, R. ; Liese, J. ; Prelog, M.
Hybrid immunity by two COVID-19 mRNA vaccinations and one breakthrough infection provides a robust and balanced cellular immune response as basic immunity against severe acute respiratory syndrome coronavirus 2.Schreiber, S. ; Dressler, L.S. ; Loffredo-Verde, E. ; Asen, T. ; Färber, S. ; Wang, W. ; Groll, T. ; Chakraborty, A. ; Kolbe, F. ; Kreer, C. ; Kosinska, A. ; Simon, S. ; Urban, S. ; Klein, F. ; Riddell, S.R. ; Protzer, U.
CARs derived from broadly neutralizing, human monoclonal antibodies identified by single B cell sorting target hepatitis B virus-positive cells.Esih, H. ; Mezgec, K. ; Billmeier, M. ; Malenšek, Š. ; Benčina, M. ; Grilc, B. ; Vidmar, S. ; Gašperlin, M. ; Bele, M. ; Zidarn, M. ; Zupanc, T.L. ; Morgan, T. ; Jordan, I. ; Sandig, V. ; Schrödel, S. ; Thirion, C. ; Protzer, U. ; Wagner, R. ; Lainšček, D. ; Jerala, R.
Mucoadhesive film for oral delivery of vaccines for protection of the respiratory tract.Willner, E.M. ; Kolbe, F. ; Momburg, F. ; Protzer, U. ; Dietz, H.
Hepatitis B virus neutralization with DNA origami nanoshells.HBV2023 ; Allweiss, L. ; Cohen, C. ; Dias, J.M.L. ; Fumagalli, V. ; Guo, H. ; Harris, J.M. ; Hu, J. ; Iannacone, M. ; Isogawa, M. ; Jeng, W.J. ; Kim, K.H. ; Kramvis, A. ; Li, W. ; Lucifora, J. ; Muramatsu, M. ; Neuveut, C. ; Ploss, A. ; Pollicino, T. ; Protzer, U. ; Tan, A. ; Tanaka, Y. ; Tu, T. ; Tsukuda, S. ; Thimme, R. ; Urban, S. ; Watashi, K. ; Yuan, Z. ; Yeh, S.H. ; McKeating, J.A. ; Revill, P.A.
Highlights from the 2023 international meeting on the molecular biology of hepatitis B virus.Hedskog, C. ; Spinner, C.D. ; Protzer, U. ; Hoffmann, D. ; Ko, C. ; Gottlieb, R.L. ; Askar, M. ; Roestenberg, M. ; de Vries, J.J.C. ; Carbo, E.C. ; Martin, R. ; Li, J. ; Han, D. ; Rodriguez, L. ; Parvangada, A. ; Perry, J.K. ; Ferrer, R. ; Anton, A. ; Andres, C. ; Casares, V. ; Günthard, H.F. ; Huber, M. ; McComsey, G.A. ; Sadri, N. ; Aberg, J.A. ; van Bakel, H. ; Porter, D.P.
No remdesivir resistance observed in the phase 3 severe and moderate COVID-19 SIMPLE trials.Roggendorf, H. ; Shouval, D.S. ; Roggendorf, M. ; Gerken, G.
Longterm outcome of therapeutic vaccination with a third generation Pre-S/S HBV vaccine (PreHevbrioR) of chronically HBV infected patients.Herranz, N. ; Gallage, S. ; Mellone, M. ; Wuestefeld, T. ; Klotz, S. ; Hanley, C.J. ; Raguz, S. ; Acosta, J.C. ; Innes, A.J. ; Banito, A. ; Georgilis, A. ; Montoya, A. ; Wolter, K. ; Dharmalingam, G. ; Faull, P. ; Carroll, T. ; Martínez-Barbera, J.P. ; Cutillas, P. ; Reisinger, F. ; Heikenwälder, M. ; Miller, R.A. ; Withers, D. ; Zender, L. ; Thomas, G.J. ; Gil, J.
Author Correction: mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype.Ramaboli, M.C. ; Ocvirk, S. ; Khan Mirzaei, M. ; Eberhart, B.L. ; Valdivia-Garcia, M. ; Metwaly, A. ; Neuhaus, K. ; Barker, G. ; Ru, J. ; Nesengani, L.T. ; Mahdi-Joest, D. ; Wilson, A.S. ; Joni, S.K. ; Layman, D.C. ; Zheng, J. ; Mandal, R. ; Chen, Q. ; Perez, M.R. ; Fortuin, S. ; Gaunt, B. ; Wishart, D. ; Methé, B. ; Haller, D. ; Li, J.V. ; Deng, L. ; Swart, R. ; O'Keefe, S.J.D.
Diet changes due to urbanization in South Africa are linked to microbiome and metabolome signatures of Westernization and colorectal cancer.Falke, S. ; Lieske, J. ; Herrmann, A. ; Loboda, J. ; Karničar, K. ; Günther, S. ; Reinke, P.Y.A. ; Ewert, W. ; Usenik, A. ; Lindič, N. ; Sekirnik, A. ; Dretnik, K. ; Tsuge, H. ; Turk, V. ; Chapman, H.N. ; Hinrichs, W. ; Ebert, G. ; Turk, D. ; Meents, A.
Structural elucidation and antiviral activity of covalent cathepsin L inhibitors.Gruber, C. ; Krautner, L. ; Bergant, V. ; Grass, V. ; Ma, Z. ; Rheinemann, L. ; Krus, A. ; Reinhardt, F. ; Mazneykova, L. ; Rocha-Hasler, M. ; Truong, D.J.J. ; Westmeyer, G.G. ; Pichlmair, A. ; Ebert, G. ; Giesert, F. ; Wurst, W.
Engineered, nucleocytoplasmic shuttling Cas13d enables highly efficient cytosolic RNA targeting.Hofmann, S. ; Luther, J. ; Plank, V. ; Oswald, A. ; Mai, J. ; Simons, I.M. ; Miller, J. ; Falcone, V. ; Hansen-Palmus, L. ; Hengel, H. ; Nassal, M. ; Protzer, U. ; Schreiner, S.
Arsenic trioxide impacts hepatitis B virus core nuclear localization and efficiently interferes with HBV infection.Tu, T. ; Wettengel, J.M. ; Xia, Y. ; Testoni, B. ; Littlejohn, M. ; Le Bert, N. ; Ebert, G. ; Verrier, E.R. ; Tavis, J.E. ; Cohen, C.
Major open questions in the hepatitis B and D field – Proceedings of the inaugural International emerging hepatitis B and hepatitis D researchers workshop.Michler, T. ; Zillinger, J. ; Hagen, P. ; Cheng, F. ; Festag, J. ; Kosinska, A. ; Protzer, U.
The lack of HBsAg secretion does neither facilitate induction of antiviral T cell responses nor Hepatitis B Virus clearance in mice.Liao, B.H. ; Platen, L. ; Grommes, M. ; Cheng, C.C. ; Holzmann-Littig, C. ; Christa, C. ; Haller, B. ; Kappler, V. ; Bester, R. ; Werz, M.L. ; Platen, E. ; Eggerer, P. ; Tréguer, L. ; Küchle, C. ; Schmaderer, C. ; Heemann, U. ; Renders, L. ; Protzer, U. ; Braunisch, M.C.
SARS-CoV-2 neutralization capacity in hemodialysis patients with and without a fifth vaccination with the updated comirnaty original/omicron BA.4-5 vaccine.Walter, N. ; Mirzaei, M.K. ; Deng, L. ; Willy, C. ; Alt, V. ; Rupp, M.
The potential of bacteriophage therapy as an alternative treatment approach for antibiotic-resistant infections.Bunz, M. ; Eisele, M. ; Hu, D. ; Ritter, M. ; Kammerloher, J. ; Lampl, S. ; Schindler, M.
CD81 suppresses NF-κB signaling and is downregulated in hepatitis C virus expressing cells.Esser, E. ; Schulte, E.C. ; Graf, A. ; Karollus, A. ; Smith, N.H. ; Michler, T. ; Dvoretskii, S. ; Angelov, A. ; Sonnabend, M. ; Peter, S.A. ; Engesser, C. ; Radonić, A. ; Thürmer, A. ; von Kleist, M. ; Gebhardt, F. ; da Costa, C.P. ; Busch, D.H. ; Muenchhoff, M. ; Blum, H. ; Keppler, O.T. ; Gagneur, J. ; Protzer, U.
Viral genome sequencing to decipher in-hospital SARS-CoV-2 transmission events.Lahmer, T. ; Weirich, G. ; Porubsky, S. ; Rasch, S. ; Kammerstetter, F.A. ; Schustetter, C. ; Schüffler, P. ; Erber, J. ; Dibos, M. ; Delbridge, C. ; Kuhn, P.H. ; Jeske, S. ; Steinhardt, M. ; Chaker, A. ; Heim, M. ; Heemann, U. ; Schmid, R.M. ; Weichert, W. ; Stock, K.F. ; Slotta-Huspenina, J.
Postmortem minimally invasive autopsy in critically Ill COVID-19 patients at the bedside: A proof-of-concept study at the ICU.Kirk, D. ; Costeira, R. ; Visconti, A. ; Khan Mirzaei, M. ; Deng, L. ; Valdes, A.M. ; Menni, C.
Bacteriophages, gut bacteria, and microbial pathways interplay in cardiometabolic health.Triebelhorn, J. ; Schneider, J. ; Spinner, C.D. ; Iakoubov, R. ; Voit, F. ; Wagner, L. ; Erber, J. ; Rothe, K. ; Berthele, A. ; Pernpeintner, V. ; Strauß, E.M. ; Renders, L. ; Willmann, A. ; Minic, M. ; Vogel, E. ; Christa, C. ; Hoffmann, D. ; Protzer, U. ; Jeske, S.
Clinical and immunological outcomes of SARS-CoV-2-infected vaccine responders, vaccine non-responders, and unvaccinated patients evaluated for neutralizing monoclonal antibody treatment at a single German tertiary care center: A retrospective cohort study with prospective follow-up.Su, J. ; Harati Taji, Z. ; Kosinska, A. ; Ates Öz, E. ; Xie, Z. ; Bielytskyi, P. ; Shein, M. ; Hagen, P. ; Esmaeili, S. ; Steiger, K. ; Protzer, U. ; Schütz, A.K.
Introducing adjuvant-loaded particulate hepatitis B core antigen as an alternative therapeutic hepatitis B vaccine component.Dähnert, L. ; Aliabadi, E. ; Fast, C. ; Hrabal, I. ; Schröder, C. ; Behrendt, P. ; Protzer, U. ; Groschup, M.H. ; Eiden, M.
Immunisation of pigs with recombinant HEV vaccines does not protect from infection with HEV genotype 3.Deerain, J.M. ; Aktepe, T.E. ; Trenerry, A.M. ; Ebert, G. ; Hyde, J.L. ; Charry, K. ; Edgington-Mitchell, L. ; Xu, B. ; Ambrose, R.L. ; Sarvestani, S.T. ; Lawlor, K.E. ; Pearson, J.S. ; White, P.A. ; Mackenzie, J.M.
Murine norovirus infection of macrophages induces intrinsic apoptosis as the major form of programmed cell death.Thiele Orberg, E. ; Meedt, E. ; Hiergeist, A. ; Xue, J. ; Heinrich, P.C. ; Ru, J. ; Ghimire, S. ; Miltiadous, O. ; Lindner, S. ; Tiefgraber, M. ; Göldel, S. ; Eismann, T. ; Schwarz, A. ; Göttert, S. ; Jarosch, S. ; Steiger, K. ; Schulz, C. ; Gigl, M. ; Fischer, J.C. ; Janssen, K.P. ; Quante, M. ; Heidegger, S. ; Herhaus, P. ; Verbeek, M. ; Ruland, J. ; van den Brink, M.R.M. ; Weber, D. ; Edinger, M. ; Wolff, D. ; Busch, D.H. ; Kleigrewe, K. ; Herr, W. ; Bassermann, F. ; Gessner, A. ; Deng, L. ; Holler, E. ; Poeck, H.
Bacteria and bacteriophage consortia are associated with protective intestinal metabolites in patients receiving stem cell transplantation.Prelog, M. ; Jeske, S.D. ; Asam, C. ; Fuchs, A. ; Wieser, A. ; Gall, C. ; Wytopil, M. ; Mueller-Schmucker, S.M. ; Beileke, S. ; Gökkaya, M. ; Kling, E. ; Geldmacher, C. ; Rubio-Acero, R. ; Plank, M. ; Christa, C. ; Willmann, A. ; Vu, M. ; Einhauser, S. ; Weps, M. ; Lampl, B.M.J. ; Almanzar, G. ; Kousha, K. ; Schwägerl, V. ; Liebl, B. ; Weber, B. ; Drescher, J. ; Scheidt, J. ; Gefeller, O. ; Messmann, H. ; Protzer, U. ; Liese, J. ; Hoelscher, M. ; Wagner, R. ; Überla, K. ; Steininger, P.
Clinical and immunological benefits of full primary COVID-19 vaccination in individuals with SARS-CoV-2 breakthrough infections: A prospective cohort study in non-hospitalized adults.COVID-19 Host Genetics Initiative (Schulte, E.C.)
Erratum to: Mapping the human genetic architecture of COVID-19 (Nature, (2021), 600, 7889, (472-477), 10.1038/s41586-021-03767-x).Xue, J. ; Mirzaei, M.K. ; Costa, R. ; Smith, S. ; Tiamani, K. ; Ma, T. ; Deng, L.
Human virome in health and disease.Riemann, J.F. ; Protzer, U.
SARS-CoV-2-the Pandemic and its Consequences Interview with Prof. Dr. Ulrike Protzer, Director of the Institute of Virology, Technical University of Munich/Helmholtz Center Munich - German Center for Environmental Health.Platen, L. ; Liao, B.H. ; Tellenbach, M. ; Cheng, C.C. ; Holzmann-Littig, C. ; Christa, C. ; Dächert, C. ; Kappler, V. ; Bester, R. ; Werz, M.L. ; Schönhals, E. ; Platen, E. ; Eggerer, P. ; Tréguer, L. ; Küchle, C. ; Schmaderer, C. ; Heemann, U. ; Keppler, O.T. ; Renders, L. ; Braunisch, M.C. ; Protzer, U.
Longitudinal SARS-CoV-2 neutralization of Omicron BA.1, BA.5 and BQ.1.1 after four vaccinations and the impact of breakthrough infections in haemodialysis patients.COVID-19 Host Genetics Initiative (Schulte, E.C. ; Protzer, U. ; Müller, N.S.)
A second update on mapping the human genetic architecture of COVID-19.Rüdiger, D. ; Kiderlen, S. ; Leong, K.W. ; Nößner, E. ; Götzfried, M.
Selektive und ortsaufgelöste Zellanbindung mit μ-PatternibiTreat.Kschonnek, M. ; Dobrovolska, I. ; Protzer, U. ; Zagst, R.
COVIX—An index allowing for the assessment of the pandemic situation based on infections and hospitalisation data.Festag, J. ; Festag, M.M. ; Asen, T. ; Wettengel, J. ; Mück-Häusl, M. ; Abdulhaqq, S. ; Stahl-Hennig, C. ; Sacha, J. ; Burwitz, B. ; Protzer, U. ; Wisskirchen, K.
Vector-mediated delivery of human MHC-I into hepatocytes enables investigation of TCR-redirected HBV-specific T cells in mice and macaque cell cultures.Reinke, P.Y.A. ; de Souza, E.E. ; Gunther, S. ; Falke, S. ; Lieske, J. ; Ewert, W. ; Loboda, J. ; Herrmann, A. ; Rahmani Mashhour, A. ; Karničar, K. ; Usenik, A. ; Lindič, N. ; Sekirnik, A. ; Botosso, V.F. ; Santelli, G.M.M. ; Kapronezai, J. ; de Araújo, M.V. ; Silva-Pereira, T.T. ; Filho, A.F.S. ; Tavares, M.S. ; Flórez-Álvarez, L. ; de Oliveira, D.B.L. ; Durigon, E.L. ; Giaretta, P.R. ; Heinemann, M.B. ; Hauser, M. ; Seychell, B. ; Böhler, H. ; Rut, W. ; Drag, M. ; Beck, T. ; Cox, R. ; Chapman, H.N. ; Betzel, C. ; Brehm, W. ; Hinrichs, W. ; Ebert, G. ; Latham, S.L. ; Guimarães, A.M.S. ; Turk, D. ; Wrenger, C. ; Meents, A.
Calpeptin is a potent cathepsin inhibitor and drug candidate for SARS-CoV-2 infections.Wettengel, J. ; Strehle, K. ; von Lucke, C. ; Roggendorf, H. ; Jeske, S.D. ; Christa, C. ; Zelger, O. ; Haller, B. ; Protzer, U. ; Knolle, P.A.
Improved detection of infection with SARS-CoV-2 Omicron variants of concern in healthcare workers by a second-generation rapid antigen test.Wang, L. ; Lyu, C. ; Stadlbauer, B. ; Buchner, A. ; Nößner, E. ; Pohla, H.
Berbamine targets cancer stem cells and reverses cabazitaxel resistance via inhibiting IGF2BP1 and p-STAT3 in prostate cancer.Luo, S. ; Ru, J. ; Khan Mirzaei, M. ; Xue, J. ; Peng, X. ; Ralser, A. ; Hadi, J.L. ; Mejías-Luque, R. ; Gerhard, M. ; Deng, L.
Helicobacter pylori infection alters gut virome by expanding temperate phages linked to increased risk of colorectal cancer.Gerbitz, A. ; Gary, R. ; Aigner, M. ; Moosmann, A. ; Kremer, A. ; Schmid, C. ; Hirschbuehl, K. ; Wagner, E. ; Hauptrock, B. ; Teschner, D. ; Roesler, W. ; Spriewald, B. ; Tischer, J. ; Moi, S. ; Balzer, H. ; Schaffer, S. ; Bausenwein, J. ; Wagner, A. ; Schmidt, F. ; Brestrich, J. ; Ullrich, B. ; Maas, S. ; Herold, S. ; Strobel, J. ; Zimmermann, R. ; Weisbach, V. ; Hansmann, L. ; Lammoglia-Cobo, F. ; Remberger, M. ; Stelljes, M. ; Ayuk, F. ; Zeiser, R. ; Mackensen, A.
Prevention of CMV/EBV reactivation by double-specific T cells in patients after allogeneic stem cell transplantation: Results from the randomized phase I/IIa MULTIVIR-01 study.Tschuck, J. ; Theilacker, L. ; Rothenaigner, I. ; Weiß, S.A.I. ; Akdogan, B. ; Lam, T.V. ; Müller, C. ; Graf, R. ; Brandner, S. ; Pütz, C. ; Rieder, T. ; Schmitt-Kopplin, P. ; Vincendeau, M. ; Zischka, H. ; Schorpp, K. ; Hadian, K.
Farnesoid X receptor activation by bile acids suppresses lipid peroxidation and ferroptosis.Garnish, S.E. ; Martin, K.R. ; Kauppi, M. ; Jackson, V.E. ; Ambrose, R. ; Eng, V.V. ; Chiou, S. ; Meng, Y. ; Frank, D. ; Tovey Crutchfield, E.C. ; Patel, K.M. ; Jacobsen, A.V. ; Atkin-Smith, G.K. ; Di Rago, L. ; Doerflinger, M. ; Horne, C.R. ; Hall, C. ; Young, S.N. ; Cook, M. ; Athanasopoulos, V. ; Vinuesa, C.G. ; Lawlor, K.E. ; Wicks, I.P. ; Ebert, G. ; Ng, A.P. ; Slade, C.A. ; Pearson, J.S. ; Samson, A.L. ; Silke, J. ; Murphy, J.M. ; Hildebrand, J.M.
A common human MLKL polymorphism confers resistance to negative regulation by phosphorylation.Barbey, C. ; Su, J. ; Billmeier, M. ; Stefan, N. ; Bester, R. ; Carnell, G. ; Temperton, N. ; Heeney, J. ; Protzer, U. ; Breunig, M. ; Wagner, R. ; Peterhoff, D.
Immunogenicity of a silica nanoparticle-based SARS-CoV-2 vaccine in mice.Luo, S. ; Ru, J. ; Mirzaei, M.K. ; Xue, J. ; Peng, X. ; Ralser, A. ; Luque, R.M. ; Gerhard, M. ; Deng, L.
Gut virome profiling identifies an association between temperate phages and colorectal cancer promoted by Helicobacter pylori infection.Llucià-Carol, L. ; Muiño, E. ; Cullell, N. ; Cárcel-Márquez, J. ; Lledós, M. ; Gallego-Fabrega, C. ; Martin-Campos, J. ; Martí-Fàbregas, J. ; Aguilera-Simón, A. ; Planas, A.M. ; DeDiego, M.L. ; de Felipe Mimbrera, A. ; Masjuan, J. ; Garcia-Madrona, S. ; Segura, T. ; González-Villar, E. ; Serrano-Heras, G. ; Domínguez Mayoral, A. ; Menéndez-Valladares, P. ; Montaner, J. ; Migeotte, I. ; Rahmouni, S. ; Darcis, G. ; Bernardo, D. ; Rojo, S. ; Schulte, E.C. ; Protzer, U. ; Fricke, L. ; Winter, C. ; Niemi, M.E.K. ; Cordioli, M. ; Delgado, P. ; Fernandez-Cadenas, I.
Genetic architecture of ischaemic strokes after COVID-19 shows similarities with large vessel strokes.Voit, F. ; Erber, J. ; Feuerherd, M. ; Fries, H. ; Bitterlich, N. ; Diehl-Wiesenecker, E. ; Gladis, S. ; Lieb, J. ; Protzer, U. ; Schneider, J. ; Geisler, F. ; Somasundaram, R. ; Schmid, R.M. ; Bauer, W. ; Spinner, C.D.
Rapid point-of-care detection of SARS-CoV-2 infection in exhaled breath using ion mobility spectrometry: A pilot study.Bunse, T. ; Körber, N. ; Wintersteller, H. ; Schneider, J. ; Graf, A. ; Radonić, A. ; Thuermer, A. ; von Kleist, M. ; Blum, H. ; Spinner, C.D. ; Bauer, T. ; Knolle, P.A. ; Protzer, U. ; Schulte, E.C.
T-cell-dominated immune response resolves protracted SARS-CoV-2 infection in the absence of neutralizing antibodies in an immunocompromised individual.Unterer, M. ; Mirzaei, M.K. ; Deng, L.
Targeted single-phage isolation reveals phage-dependent heterogeneous infection dynamics.Hoffmann, D.
The role of the oral cavity in SARS-CoV-2- and other viral infections.Chen, J. ; Wang, X. ; Schmalen, A. ; Haines, S. ; Wolff, M. ; Ma, H. ; Zhang, H. ; Stoleriu, M.-G. ; Nowak, J. ; Nakayama, M. ; Bueno, M. ; Brands, J. ; Mora, A.L. ; Lee, J.S. ; Krauss-Etschmann, S. ; Dmitrieva, A. ; Frankenberger, M. ; Hofer, T.P. ; Nößner, E. ; Moosmann, A. ; Behr, J. ; Milger, K. ; Deeg, C.A. ; Staab-Weijnitz, C.A. ; Hauck, S.M. ; Adler, H. ; Goldmann, T. ; Gaede, K.I. ; Behrends, J. ; Kammerl, I.E. ; Meiners, S.
Antiviral CD8+T-cell immune responses are impaired by cigarette smoke and in COPD.Schmalen, A. ; Kammerl, I.E. ; Meiners, S. ; Nößner, E. ; Deeg , C.A. ; Hauck, S.M.
A lysine residue at the C-terminus of MHC class I ligands correlates with low C-terminal proteasomal cleavage probability.Körber, N. ; Holzmann-Littig, C. ; Wilkens, G. ; Liao, B.H. ; Werz, M.L. ; Platen, L. ; Cheng, C.C. ; Tellenbach, M. ; Kappler, V. ; Lehner, V. ; Mijočević, H. ; Christa, C. ; Assfalg, V. ; Heemann, U. ; Schmaderer, C. ; Protzer, U. ; Braunisch, M.C. ; Bauer, T. ; Renders, L.
Comparable cellular and humoral immunity upon homologous and heterologous COVID-19 vaccination regimens in kidney transplant recipients.Esser, K. ; Cheng, X. ; Wettengel, J.M. ; Lucifora, J. ; Hansen-Palmus, L. ; Austen, K. ; Roca Suarez, A.A. ; Heintz, S. ; Testoni, B. ; Nebioglu, F. ; Pham, M.T. ; Yang, S. ; Zernecke, A. ; Wohlleber, D. ; Ringelhan, M. ; Broxtermann, M. ; Hartmann, D. ; Hüser, N. ; Mergner, J. ; Pichlmair, A. ; Thasler, W.E. ; Heikenwälder, M. ; Gasteiger, G. ; Blutke, A. ; Walch, A.K. ; Knolle, P.A. ; Bartenschlager, R. ; Protzer, U.
Hepatitis B virus targets lipid transport pathways to infect hepatocytes.Ralser, A. ; Dietl, A. ; Jarosch, S. ; Engelsberger, V. ; Wanisch, A. ; Janssen, K.P. ; Middelhoff, M. ; Vieth, M. ; Quante, M. ; Haller, D. ; Busch, D. ; Deng, L. ; Mejías-Luque, R. ; Gerhard, M.
Helicobacter pylori promotes colorectal carcinogenesis by deregulating intestinal immunity and inducing a mucus-degrading microbiota signature.Ru, J. ; Khan Mirzaei, M. ; Xue, J. ; Peng, X. ; Deng, L.
ViroProfiler: A containerized bioinformatics pipeline for viral metagenomic data analysis.Göttig, L. ; Weiß, C. ; Stubbe, M. ; Hanrieder, L. ; Hofmann, S. ; Grodziecki, A. ; Stadler, D. ; Carpentier, A. ; Protzer, U. ; Schreiner, S.
Apobec3A deamination functions are involved in antagonizing efficient human adenovirus replication and gene expression.Lettl, C. ; Schindele, F. ; Mehdipour, A.R. ; Steiner, T. ; Ring, D. ; Brack-Werner, R. ; Stecher, B. ; Eisenreich, W. ; Bilitewski, U. ; Hummer, G. ; Witschel, M. ; Fischer, W. ; Haas, R.
Selective killing of the human gastric pathogen Helicobacter pylori by mitochondrial respiratory complex I inhibitors.Wettengel, J.M. ; Hansen-Palmus, L. ; Yusova, S. ; Rust, L. ; Biswas, S. ; Carson, J. ; Ryu, J. ; Bimber, B.N. ; Hennebold, J.D. ; Burwitz, B.J.
A multifunctional and highly adaptable reporter system for CRISPR/Cas editing.Hofmann, S. ; Plank, V. ; Groitl, P. ; Skvorc, N. ; Hofmann, K. ; Luther, J. ; Ko, C. ; Zimmerman, P. ; Bruss, V. ; Stadler, D. ; Carpentier, A. ; Rezk, S. ; Nassal, M. ; Protzer, U. ; Schreiner, S.
SUMO modification of hepatitis B virus core mediates nuclear entry, promyelocytic leukemia nuclear body association, and efficient formation of covalently closed circular DNA.Ngoc Tram, H.T. ; Thu Huong, B.T. ; Duc Hinh, N. ; Thuy, P.T. ; Lan Anh, L.T. ; Kim Phuon, D.T. ; Thu Lan, H. ; Cam Tu, H. ; Körber, N. ; Bauer, T. ; Khanh Lam, H. ; Manh Ha, N. ; Minh Duc, N. ; Thanh Hiep, N. ; Protzer, U. ; Tien Dung, N.
Multidimensional analysis of the mother-to-child transmission risk factors in chronic hepatitis B virus infection in pregnant women in Vietnam.Liebl, K. ; Aschenbrenner, I. ; Schiller, L. ; Kerle, A. ; Protzer, U. ; Feige, M.J.
Modeling of the human interleukin 12:receptor complex allows to engineer attenuated cytokine variants.Gong, H. ; Xue, B. ; Ru, J. ; Pei, G. ; Li, Y.
Targeted therapy for EWS-FLI1 in ewing sarcoma.Ru, J. ; Xue, J. ; Sun, J. ; Cova, L. ; Deng, L.
Unveiling the hidden role of aquatic viruses in hydrocarbon pollution bioremediation.Wettengel, J.M. ; Bunse, T. ; Jeske, S.D. ; Wölfel, R. ; Zange, S. ; Taeubner, J. ; Goelnitz, U. ; Protzer, U.
Implementation and clinical evaluation of an Mpox virus laboratory-developed test on a fully automated random-access platform.Osterman, A. ; Krenn, F. ; Iglhaut, M. ; Badell, I. ; Lehner, A. ; Späth, P.M. ; Stern, M. ; Both, H. ; Bender, S. ; Muenchhoff, M. ; Graf, A. ; Krebs, S. ; Blum, H. ; Grimmer, T. ; Durner, J. ; Czibere, L. ; Dächert, C. ; Grzimek-Koschewa, N. ; Protzer, U. ; Kaderali, L. ; Baldauf, H.M. ; Keppler, O.T.
Automated antigen assays display a high heterogeneity for the detection of SARS-CoV-2 variants of concern, including several Omicron sublineages.Beck, C. ; Ramanujam, D. ; Vaccarello, P. ; Widenmeyer, F. ; Feuerherd, M. ; Cheng, C.C. ; Bomhard, A. ; Abikeeva, T. ; Schädler, J. ; Sperhake, J.P. ; Graw, M. ; Safi, S. ; Hoffmann, H. ; Staab-Weijnitz, C.A. ; Rad, R. ; Protzer, U. ; Frischmuth, T. ; Engelhardt, S.
Trimannose-coupled antimiR-21 for macrophage-targeted inhalation treatment of acute inflammatory lung damage.Nieborak, A. ; Lukauskas, S. ; Capellades, J. ; Heyn, P. ; Santos, G.S. ; Motzler, K. ; Zeigerer, A. ; Bester, R. ; Protzer, U. ; Schelter, F. ; Wagner, M. ; Carell, T. ; Hruscha, A. ; Schmid, B. ; Yanes, O. ; Schneider, R.
Depletion of pyruvate kinase (PK) activity causes glycolytic intermediate imbalances and reveals a PK-TXNIP regulatory axis.Willy, C. ; Bugert, J.J. ; Classen, A.Y. ; Deng, L. ; Düchting, A. ; Gross, J. ; Hammerl, J.A. ; Korf, I.H.E. ; Kühn, C. ; Lieberknecht-Jouy, S. ; Rohde, C. ; Rupp, M. ; Vehreschild, M.J.G.T. ; Vogele, K. ; Wienecke, S. ; Witzenrath, M. ; Würstle, S. ; Ziehr, H. ; Moelling, K. ; Broecker, F.
Phage therapy in Germany-update 2023.Stephan, A.-S. ; Kosinska, A. ; Mück-Häusl, M. ; Muschaweckh, A. ; Jager, C. ; Röder, N. ; Heikenwälder, M. ; Dembek, C.J. ; Protzer, U.
Evaluation of the effect of CD70 co-expression on CD8 T cell response in protein-prime MVA-boost vaccination in mice.Manapov, F. ; Nieto, A. ; Käsmann, L. ; Taugner, J. ; Kenndoff, S. ; Flörsch, B. ; Guggenberger, J. ; Hofstetter, K. ; Kröninger, S. ; Lehmann, J. ; Kravutske, H. ; Pelikan, C. ; Belka, C. ; Eze, C.
Five years after PACIFIC: Update on multimodal treatment efficacy based on real-world reports.Sun, J. ; Ru, J. ; Ramos-Mucci, L. ; Qi, F. ; Chen, Z. ; Chen, S. ; Cribbs, A.P. ; Deng, L. ; Wang, X.
DeepsmirUD: Prediction of regulatory effects on microRNA expression mediated by small molecules using deep learning.Kohantorabi, M. ; Wagstaffe, M. ; Creutzburg, M. ; Ugolotti, A. ; Kulkarni, S. ; Jeromin, A. ; Krekeler, T. ; Feuerherd, M. ; Herrmann, A. ; Ebert, G. ; Protzer, U. ; Guédez, G. ; Löw, C. ; Thuenauer, R. ; Schlueter, C. ; Gloskovskii, A. ; Keller, T.F. ; Di Valentin, C. ; Stierle, A. ; Noei, H.
Adsorption and inactivation of SARS-CoV-2 on the surface of anatase TiO2(101).Tergast, T.L. ; Protzer, U. ; Zeuzem, S. ; Heitmann, L. ; Sarrazin, C. ; Lehmann, M. ; Ingiliz, P. ; Cornberg, M. ; Zimmermann, R. ; Gerlich, M.G. ; Buggisch, P. ; Wiebner, B. ; Wedemeyer, H.
Strategietreffen: Virushepatitis in Deutschland eliminieren.Hintze, S. ; Möhl, B.S. ; Beyerl, J. ; Wulff, K. ; Wieser, A. ; Bork, K. ; Meinke, P.
Mutant plasminogen in hereditary angioedema is bypassing FXII/kallikrein to generate bradykinin.Sacherl, J. ; Kosinska, A. ; Kemter, K. ; Kächele, M. ; Laumen, S.C. ; Kerth, H.A. ; Öz, E.A. ; Wolff, L.S. ; Su, J. ; Essbauer, S. ; Sutter, G. ; Scholz, M. ; Singethan, K. ; Altrichter, J. ; Protzer, U.
Efficient stabilization of therapeutic hepatitis B vaccine components by amino-acid formulation maintains its potential to break immune tolerance.Keppler-Hafkemeyer, A. ; Greil, C. ; Wratil, P.R. ; Shoumariyeh, K. ; Stern, M. ; Hafkemeyer, A. ; Ashok, D. ; Hollaus, A. ; Lupoli, G. ; Priller, A. ; Bischof, M.L. ; Ihorst, G. ; Engelhardt, M. ; Marks, R. ; Finke, J. ; Bertrand, H. ; Dächert, C. ; Muenchhoff, M. ; Badell, I. ; Emmerich, F. ; Halder, H. ; Spaeth, P.M. ; Knolle, P.A. ; Protzer, U. ; von Bergwelt-Baildon, M. ; Duyster, J. ; Hartmann, T.N. ; Moosmann, A. ; Keppler, O.T.
Potent high-avidity neutralizing antibodies and T cell responses after COVID-19 vaccination in individuals with B cell lymphoma and multiple myeloma.Jaitner, S. ; Pretzsch, E. ; Neumann, J. ; Schäffauer, A. ; Schiemann, M. ; Angele, M. ; Kumbrink, J. ; Schwitalla, S. ; Greten, F.R. ; Brandl, L. ; Klauschen, F. ; Horst, D. ; Kirchner, T. ; Jung, A.
Olfactomedin 4 associates with expression of differentiation markers but not with properties of cancer stemness, EMT nor metastatic spread in colorectal cancer.Klüpfel, J. ; Paßreiter, S. ; Rumpf, M.P. ; Christa, C. ; Holthoff, H.P. ; Ungerer, M. ; Lohse, M.J. ; Knolle, P. ; Protzer, U. ; Elsner, M. ; Seidel, M.
Automated detection of neutralizing SARS-CoV-2 antibodies in minutes using a competitive chemiluminescence immunoassay.Degenhardt, F. ; Ellinghaus, D. ; Juzenas, S. ; Lerga-Jaso, J. ; Wendorff, M. ; Maya-Miles, D. ; Uellendahl-Werth, F. ; ElAbd, H. ; Rühlemann, M.C. ; Ozer, O. ; Lenning, O.B. ; Myhre, R. ; Vadla, M.S. ; Wacker, E.M. ; Wienbrandt, L. ; Ortiz, A.B. ; Salazar, A. ; Chercoles, A.G. ; Palom, A. ; Ruiz, A. ; Garcia-Fernandez, A.E. ; Blanco-Grau, A. ; Mantovani, A. ; Zanella, A. ; Holten, A.R. ; Mayer, A. ; Bandera, A. ; Cherubini, A. ; Protti, A. ; Aghemo, A. ; Gerussi, A. ; Braun, A. ; Nebel, A. ; Barreira, A. ; Lleõ, A. ; Teles, A. ; Kildal, A.B. ; Biondi, A. ; Caballero-Garralda, A. ; Ganna, A. ; Gori, A. ; Glück, A. ; Lind, A. ; Tanck, A. ; Hinney, A. ; Nolla, A.C. ; Fracanzani, A.L. ; Peschuck, A. ; Cavallero, A. ; Dyrhol-Riise, A.M. ; Ruello, A. ; Julià, A. ; Muscatello, A. ; Pesenti, A. ; Voza, A. ; Rando-Segura, A. ; Solier, A. ; Schmidt, A. ; Cortes, B. ; Mateos, B. ; Nafría-Jiménez, B. ; Schaefer, B.W. ; Jensen, B. ; Bellinghausen, C. ; Maj, C. ; Ferrando, C. ; Quereda, C. ; Skurk, C. ; Thibeault, C. ; Scollo, C. ; Herr, C. ; Spinner, C.D. ; Gassner, C. ; Lange, C. ; Hu, C. ; Paccapelo, C. ; Lehmann, C. ; Angelini, C. ; Cappadona, C. ; Azuure, C. ; COVICAT study group, Aachen Study (COVAS) ; Bianco, C. ; Cea, C. ; Sancho, C. ; Hoff, D.A.L. ; Galimberti, D. ; Prati, D. ; Haschka, D. ; Jimenez, D.L.R.M. ; Pestaña, D. ; Toapanta, D. ; Muñiz-Diaz, E. ; Azzolini, E. ; Sandoval, E. ; Binatti, E. ; Scarpini, E. ; Helbig, E.T. ; Casalone, E. ; Urrechaga, E. ; Paraboschi, E.M. ; Pontali, E. ; Reverter, E. ; Navas, E. ; Solligård, E. ; Contro, E. ; Arana-Arri, E. ; Aziz, F. ; Garcia, F. ; Sánchez, F.G. ; Ceriotti, F. ; Martinelli-Boneschi, F. ; Peyvandi, F. ; Kurth, F. ; Blasi, F. ; Malvestiti, F. ; Mesonero, F. ; Rodriguez-Frias, F. ; Hanses, F. ; Müller, F. ; Hemmrich-Stanisak, G. ; Bellani, G. ; Grasselli, G. ; Pezzoli, G. ; Costantino, G. ; Albano, G. ; Cardamone, G. ; Bellelli, G. ; Citerio, G. ; Foti, G. ; Lamorte, G. ; Matullo, G. ; Baselli, G. ; Kurihara, H. ; Neb, H. ; My, I. ; Kurth, I. ; Hernández, I. ; Pink, I. ; Rojas, I. ; Galván-Femenia, I. ; Holter, J.C. ; Afset, J.E. ; Heyckendorf, J. ; Kässens, J. ; Damås, J.K. ; Rybniker, J. ; Altmüller, J. ; Martin, J. ; Erdmann, J. ; Banales, J.M. ; Badia, J.R. ; Dopazo, J. ; Schneider, J. ; Bergan, J. ; Barretina, J. ; Walter, J. ; Quero, J.H. ; Goikoetxea, J. ; Guerrero, J.M. ; Fazaal, J. ; Kraft, J. ; Schröder, J. ; Risnes, K. ; Banasik, K. ; Müller, K.E. ; Gaede, K.I. ; Garcia-Etxebarria, K. ; Tonby, K. ; Heggelund, L. ; Izquierdo-Sanchez, L. ; Bettini, L.R. ; Sumoy, L. ; Sander, L.E. ; Lippert, L.J. ; Terranova, L. ; Nkambule, L. ; Knopp, L. ; Gustad, L.T. ; Garbarino, L. ; Santoro, L. ; Téllez, L. ; Roade, L. ; Ostadreza, M. ; Intxausti, M. ; Kogevinas, M. ; Riveiro-Barciela, M. ; Berger, M.M. ; Schaefer, M. ; Niemi, M.E.K. ; Gutiérrez-Stampa, M.A. ; Carrabba, M. ; Figuera Basso, M.E. ; Valsecchi, M.G. ; Hernandez-Tejero, M. ; Vehreschild, M.J.G.T. ; Manunta, M. ; Acosta-Herrera, M. ; D'Angiò, M. ; Baldini, M. ; Cazzaniga, M. ; Grimsrud, M.M. ; Cornberg, M. ; Nöthen, M.M. ; Marquié, M. ; Castoldi, M. ; Cordioli, M. ; Cecconi, M. ; D'Amato, M. ; Augustin, M. ; Tomasi, M. ; Boada, M. ; Dreher, M.R. ; Seilmaier, M.J. ; Joannidis, M. ; Wittig, M. ; Mazzocco, M. ; Ciccarelli, M. ; Rodríguez-Gandía, M. ; Bocciolone, M. ; Miozzo, M. ; Ayo, N.I. ; Blay, N. ; Chueca, N. ; Montano, N. ; Braun, N. ; Ludwig, N. ; Marx, N. ; Martínez, N. ; Cornely, O.A. ; Witzke, O. ; Palmieri, O. ; Faverio, P. ; Preatoni, P. ; Bonfanti, P. ; Omodei, P. ; Tentorio, P. ; Castro, P. ; Rodrigues, P.M. ; España, P.P. ; Hoffmann, P. ; Rosenstiel, P. ; Schommers, P. ; Suwalski, P. ; Pablo, R. ; Ferrer, R. ; Bals, R. ; Gualtierotti, R. ; Gallego-Durán, R. ; Nieto, R. ; Carpani, R. ; Badalamenti, S. ; Haider, S. ; Ciesek, S. ; May, S. ; Bombace, S. ; Marsal, S. ; Pigazzini, S. ; Klein, S. ; Pelusi, S. ; Wilfling, S. ; Bosari, S. ; Volland, S. ; Brunak, S. ; Schreiber, S. ; Heilmann-Heimbach, S. ; Aliberti, S. ; Ripke, S. ; Dudman, S. ; Wesse, T. ; Zheng, T. ; Bahmer, T. ; Eggermann, T. ; Illig, T. ; Brenner, T. ; Pumarola, T. ; Feldt, T. ; Folseraas, T. ; Cejudo, T.G. ; Landmesser, U. ; Protzer, U. ; Hehr, U. ; Rimoldi, V. ; Monzani, V.
Detailed stratified GWAS analysis for severe COVID-19 in four European populations.Su, J. ; Brunner, L. ; Ates Öz, E. ; Sacherl, J. ; Frank, G. ; Kerth, H.A. ; Thiele, F. ; Wiegand, M. ; Mogler, C. ; Aguilar, J.C. ; Knolle, P.A. ; Collin, N. ; Kosinska, A. ; Protzer, U.
Activation of CD4 T cells during prime immunization determines the success of a therapeutic hepatitis B vaccine in HBV-carrier mouse models.Hofer, T.P. ; Nieto, A. ; Kaesmann, L. ; Taugner, J. ; Pelikan, C. ; Katanov, D. ; Eze, C. ; Guggenberger, J. ; Belka, C. ; Nößner, E. ; Manapov, F.
Absence of CD4(+) and CD8(+) T cell expansion after primary multimodal treatment predicts early progression in inoperable stage III NSCLC.Maurer, H.C. ; Schult, D. ; Koyumdzhieva, P. ; Reitmeier, S. ; Middelhoff, M. ; Rasch, S. ; List, M. ; Janssen, K.P. ; Steiger, K. ; Protzer, U. ; Schmid, R.M. ; Neuhaus, K. ; Haller, D. ; Quante, M. ; Lahmer, T.
Gut microbial disruption in critically Ill patients with COVID-19-associated pulmonary aspergillosis.Walker, A. ; Schwarz, T. ; Brinkmann-Paulukat, J. ; Wisskirchen, K. ; Menne, C. ; Alizei, E.S. ; Kefalakes, H. ; Theissen, M. ; Hoffmann, D. ; Schulze zur Wiesch, J. ; Maini, M.K. ; Cornberg, M. ; Kraft, A.R.M. ; Keitel, V. ; Bock, H.H. ; Horn, P.A. ; Thimme, R. ; Wedemeyer, H. ; Heinemann, F.M. ; Luedde, T. ; Neumann-Haefelin, C. ; Protzer, U. ; Timm, J.
Immune escape pathways from the HBV core18-27 CD8 T cell response are driven by individual HLA class I alleles.Debelec-Butuner, B. ; Quitt, O. ; Schreiber, S. ; Momburg, F. ; Wisskirchen, K. ; Protzer, U.
Activation of distinct antiviral T-cell immunity: A comparison of bi- and trispecific T-cell engager antibodies with a chimeric antigen receptor targeting HBV envelope proteins.Butler-Laporte, G. ; Povysil, G. ; Kosmicki, J.A. ; Cirulli, E.T. ; Drivas, T. ; Furini, S. ; Saad, C. ; Schmidt, A. ; Olszewski, P.K. ; Korotko, U. ; Quinodoz, M. ; Çelik, E. ; Kundu, K. ; Walter, K. ; Jung, J. ; Stockwell, A.D. ; Sloofman, L.G. ; Jordan, D.M. ; Thompson, R.C. ; Del Valle, D. ; Simons, N. ; Cheng, E. ; Sebra, R. ; Schadt, E.E. ; Kim-Schulze, S. ; Gnjatic, S. ; Merad, M. ; Buxbaum, J.D. ; Beckmann, N.D. ; Charney, A.W. ; Przychodzen, B. ; Chang, T. ; Pottinger, T.D. ; Shang, N. ; Brand, F. ; Fava, F. ; Mari, F. ; Chwialkowska, K. ; Niemira, M. ; Pula, S. ; Baillie, J.K. ; Stuckey, A. ; Salas, A. ; Bello, X. ; Pardo-Seco, J. ; Gómez-Carballa, A. ; Rivero-Calle, I. ; Martinón-Torres, F. ; Ganna, A. ; Karczewski, K.J. ; Veerapen, K. ; Bourgey, M. ; Bourque, G. ; Eveleigh, R.J. ; Forgetta, V. ; Morrison, D. ; Langlais, D. ; Lathrop, M. ; Mooser, V. ; Nakanishi, T. ; Frithiof, R. ; Hultström, M. ; Lipcsey, M. ; Marincevic-Zuniga, Y. ; Nordlund, J. ; Schiabor Barrett, K.M. ; Lee, W. ; Bolze, A. ; White, S. ; Riffle, S. ; Tanudjaja, F. ; Sandoval, E. ; Neveux, I. ; Dabe, S. ; Casadei, N. ; Motameny, S. ; Alaamery, M. ; Massadeh, S. ; Aljawini, N. ; Almutairi, M.S. ; Arabi, Y.M. ; Alqahtani, S.A. ; Al Harthi, F.S. ; Almutairi, A. ; Alqubaishi, F. ; Alotaibi, S. ; Binowayn, A. ; Alsolm, E.A. ; El Bardisy, H. ; Fawzy, M. ; Cai, F. ; Soranzo, N. ; Butterworth, A. ; COVID-19 Host Genetics Initiative ; DeCOI Host Genetics Group ; GEN-COVID Multicenter Study (Italy) ; Mount Sinai Clinical Intelligence Center ; GEN-COVID consortium (Spain) ; GenOMICC Consortium ; Japan COVID-19 Task Force ; Regeneron Genetics Center ; Geschwind, D.H. ; Arteaga, S. ; Stephens, A.E. ; Butte, M.J. ; Boutros, P.C. ; Yamaguchi, T.N. ; Tao, S. ; Eng, S. ; Sanders, T. ; Tung, P.J. ; Broudy, M.E. ; Pan, Y. ; González, A.J. ; Chavan, N. ; Johnson, R. ; Pasaniuc, B. ; Yaspan, B.L. ; Smieszek, S. ; Rivolta, C. ; Bibert, S. ; Bochud, P.Y. ; Dabrowski, M. ; Zawadzki, P. ; Sypniewski, M. ; Kaja, E. ; Chariyavilaskul, P. ; Nilaratanakul, V. ; Hirankarn, N. ; Shotelersuk, V. ; Pongpanich, M. ; Phokaew, C. ; Chetruengchai, W. ; Tokunaga, K. ; Sugiyama, M. ; Kawai, Y. ; Hasegawa, T. ; Naito, T. ; Namkoong, H. ; Edahiro, R. ; Kimura, A. ; Ogawa, S. ; Kanai, T. ; Fukunaga, K. ; Imoto, S. ; Miyano, S. ; Mangul, S. ; Abedalthagafi, M.S. ; Zeberg, H. ; Grzymski, J.J. ; Washington, N.L. ; Ossowski, S. ; Ludwig, K.U. ; Schulte, E.C. ; Riess, O. ; Moniuszko, M. ; Kwasniewski, M. ; Mbarek, H. ; Ismail, S.I. ; Verma, A. ; Goldstein, D.B. ; Kiryluk, K. ; Renieri, A. ; Richards, J.B.
Exome-wide association study to identify rare variants influencing COVID-19 outcomes: Results from the Host Genetics Initiative.Svilenov, H.L. ; Bester, R. ; Sacherl, J. ; Absmeier, R. ; Peters, C. ; Protzer, U. ; Brockmeyer, C. ; Buchner, J.
Multimeric ACE2-IgM fusions as broadly active antivirals that potently neutralize SARS-CoV-2 variants.Bauer, A. ; Pachl, E. ; Hellmuth, J.C. ; Kneidinger, N. ; Heydarian, M. ; Frankenberger, M. ; Stubbe, H.C. ; Ryffel, B. ; Petrera, A. ; Hauck, S.M. ; Behr, J. ; Kaiser, R. ; Scherer, C. ; Deng, L. ; Teupser, D. ; Ahmidi, N. ; Muenchhoff, M. ; Schubert, B. ; Hilgendorff, A.
Proteomics reveals antiviral host response and NETosis during acute COVID-19 in high-risk patients.Sarvnaz, H. ; Asadi-Asadabad, S. ; Amiri, M.M. ; Ghaedi, M. ; Protzer, U. ; Jeddi-Tehrani, M. ; Golsaz-Shirazi, F. ; Shokri, F.
Optimization of an efficient cell culture hepatitis B infection system for assessment of hepatitis B virus neutralizing monoclonal antibodies.Elbehery, A.H.A. ; Deng, L.
Insights into the global freshwater virome.Wu, R. ; Cao, Z. ; Jiang, Y. ; Chen, W. ; Sun, Y. ; Li, Q. ; Mi, J. ; Deng, L. ; Liao, X. ; Feng, Y. ; Lan, T. ; Ma, J.
Early life dynamics of ARG and MGE associated with intestinal virome in neonatal piglets.Nückel, J. ; Planatscher, E. ; Mohr, A.W. ; Deichl, K. ; Mijočević, H. ; Feuerherd, M. ; Wolff, L.S. ; Erber, J. ; Schneider, J. ; Quante, M. ; Winter, C. ; Ruland, J. ; Hapfelmeier, A. ; Hammerschmidt, W. ; Moosmann, A. ; Protzer, U. ; Behrends, U. ; Mautner, J.
Association between IgG responses against the nucleocapsid proteins of alphacoronaviruses and COVID-19 severity.Lyu, C. ; Wang, L. ; Stadlbauer, B. ; Nößner, E. ; Buchner, A. ; Pohla, H.
Identification of EZH2 as cancer stem cell marker in clear cell renal cell carcinoma and the anti-tumor effect of epigallocatechin-3-gallate (EGCG).Cheng, C.C. ; Platen, L. ; Christa, C. ; Tellenbach, M. ; Kappler, V. ; Bester, R. ; Liao, B.H. ; Holzmann-Littig, C. ; Werz, M. ; Schönhals, E. ; Platen, E. ; Eggerer, P. ; Tréguer, L. ; Küchle, C. ; Schmaderer, C. ; Heemann, U. ; Renders, L. ; Protzer, U. ; Braunisch, M.C.
Improved SARS-CoV-2 neutralization of delta and omicron BA.1 variants of concern after fourth vaccination in hemodialysis patients.Kreft, L. ; Schepers, A. ; Hils, M. ; Swiontek, K. ; Flatley, A. ; Janowski, R. ; Mirzaei, M.K. ; Dittmar, M. ; Chakrapani, N. ; Desai, M.S. ; Eyerich, S. ; Deng, L. ; Niessing, D. ; Fischer, K. ; Feederle, R. ; Blank, S. ; Schmidt-Weber, C.B. ; Hilger, C. ; Biedermann, T. ; Ohnmacht, C.
A novel monoclonal IgG1 antibody specific for Galactose-alpha-1,3-galactose questions alpha-Gal epitope expression by bacteria.Entfellner, E. ; Li, R. ; Jiang, Y. ; Ru, J. ; Blom, J. ; Deng, L. ; Kurmayer, R.
Toxic/bioactive peptide synthesis genes rearranged by insertion sequence elements among the bloom-forming cyanobacteria Planktothrix.Zeinali, T. ; Faraji, N. ; Joukar, F. ; Khan Mirzaei, M. ; Kafshdar Jalali, H. ; Shenagari, M. ; Mansour-Ghanaei, F.
Gut bacteria, bacteriophages, and probiotics: Tripartite mutualism to quench the SARS-CoV2 storm.Tu, T. ; Zehnder, B. ; Wettengel, J.M. ; Zhang, H. ; Coulter, S. ; Ho, V. ; Douglas, M.W. ; Protzer, U. ; George, J. ; Urban, S.
Mitosis of hepatitis B virus-infected cells in vitro results in uninfected daughter cells.Brech, D. ; Herbstritt, A. ; Diederich, S. ; Straub, T. ; Kokolakis, E. ; Irmler, M. ; Beckers, J. ; Büttner, F.A. ; Schaeffeler, E. ; Winter, S. ; Nelson, P.J. ; Nößner, E.
Dendritic cells or macrophages? The microenvironment of human clear cell renal cell carcinoma imprints a mosaic myeloid subtype associated with patient survival.Sinha, A. ; Li, Y. ; Mirzaei, M.K. ; Shamash, M. ; Samadfam, R. ; King, I.L. ; Maurice, C.F.
Transplantation of bacteriophages from ulcerative colitis patients shifts the gut bacteriome and exacerbates the severity of DSS colitis.Vogel, E. ; Kocher, K. ; Priller, A. ; Cheng, C.-C. ; Steininger, P. ; Liao, B.-H. ; Körber, N. ; Willmann, A. ; Irrgang, P. ; Held, J. ; Moosmann, C. ; Schmidt, V. ; Beileke, S. ; Wytopil, M. ; Heringer, S. ; Bauer, T. ; Brockhoff, R. ; Jeske, S. ; Mijočević, H. ; Christa, C. ; Salmanton-García, J. ; Tinnefeld, K. ; Bogdan, C. ; Yazici, S. ; Knolle, P. ; Cornely, O.A. ; Überla, K. ; Protzer, U. ; Schober, K. ; Tenbusch, M.
Dynamics of humoral and cellular immune responses after homologous and heterologous SARS-CoV-2 vaccination with ChAdOx1 nCoV-19 and BNT162b2.Cruz, R. ; Almeida, S.D. ; Heredia, M.L. ; Quintela, I. ; Ceballos, F.C. ; Pita, G. ; Lorenzo-Salazar, J.M. ; González-Montelongo, R. ; Gago-Dominguez, M. ; Porras, M.S. ; Castaño, J.A.T. ; Nevado, J. ; Aguado, J.M. ; Aguilar, C. ; Aguilera-Albesa, S. ; Almadana, V. ; Almoguera, B. ; Alvarez, N. ; Andreu-Bernabeu, ; Arana-Arri, E. ; Arango, C. ; Arranz, M.J. ; Artiga, M.J. ; Baptista-Rosas, R.C. ; Barreda-Sánchez, M. ; Belhassen-Garcia, M. ; Bezerra, J.F. ; Bezerra, M.A.C. ; Boix-Palop, L. ; Brion, M. ; Brugada, R. ; Bustos, M. ; Calderón, E.J. ; Carbonell, C. ; Castelao, J.E. ; Conde-Vicente, R. ; Cordero-Lorenzana, M.L. ; Cortes-Sanchez, J.L. ; Corton, M. ; Darnaude, M.T. ; De Martino-Rodríguez, A. ; Campo-Pérez, V. ; Bustamante, A.D. ; Domínguez-Garrido, E. ; Luchessi, A.D. ; Eirós, R. ; Sanabria, G.M.E. ; Fariñas, M.C. ; Fernández-Robelo, U. ; Fernández-Rodríguez, A. ; Fernández-Villa, T. ; Gil-Fournier, B. ; Gómez-Arrue, J. ; Álvarez, B.G. ; Quirós, F.G.B. ; González-Peñas, J. ; Gutiérrez-Bautista, J.F. ; Herrero, M.J. ; Herrero-Gonzalez, A. ; Jimenez-Sousa, M.A. ; Lattig, M.C. ; Borja, A.L. ; Lopez-Rodriguez, R. ; Mancebo, E. ; Martín-López, C. ; Martín, V. ; Martinez-Nieto, O. ; Martinez-Lopez, I. ; Martinez-Resendez, M.F. ; Martinez-Perez, ; Mazzeu, J.A. ; Macías, E.M. ; Minguez, P. ; Cuerda, V.M. ; Silbiger, V.N. ; Oliveira, S.F. ; Ortega-Paino, E. ; Parellada, M. ; Paz-Artal, E. ; Santos, N.P.C. ; Pérez-Matute, P. ; Perez, P. ; Pérez-Tomás, M.E. ; Perucho, T. ; Pinsach-Abuin, M.L. ; Pompa-Mera, E.N. ; Porras-Hurtado, G.L. ; Pujol, A. ; León, S.R. ; Resino, S. ; Fernandes, M.R. ; Rodríguez-Ruiz, E. ; Rodriguez-Artalejo, F. ; Rodriguez-Garcia, J.A. ; Ruiz-Cabello, F. ; Ruiz-Hornillos, J. ; Ryan, P. ; Soria, J.M. ; Souto, J.C. ; Tamayo, E. ; Tamayo-Velasco, A. ; Taracido-Fernandez, J.C. ; Teper, A. ; Torres-Tobar, L. ; Urioste, M. ; Valencia-Ramos, J. ; Yáñez, Z. ; Zarate, R. ; Pigazzini, S. ; Degenhardt, F. ; Butler-Laporte, G. ; Maya-Miles, D. ; Bujanda, L. ; Bouysran, Y. ; Palom, A. ; Ellinghaus, D. ; Martínez-Bueno, M. ; Rolker, S. ; Amitrano, S. ; Roade, L. ; Fava, F. ; Spinner, C.D. ; Prati, D. ; Bernardo, D. ; Garcia, F. ; Darcis, G. ; Fernandez-Cadenas, I. ; Holter, J.C. ; Banales, J.M. ; Frithiof, R. ; Duga, S. ; Asselta, R. ; Pereira, A.C. ; Romero-Gómez, M. ; Nafría-Jiménez, B. ; Hov, J.R. ; Migeotte, I. ; Renieri, A. ; Planas, A.M. ; Ludwig, K.U. ; Buti, M. ; Rahmouni, S. ; Alarcón-Riquelme, M.E. ; Schulte, E.C. ; Franke, A. ; Karlsen, T.H. ; Valenti, L. ; Zeberg, H. ; Richards, B. ; Ganna, A. ; Boada, M. ; Rojas, I. ; Ruiz, A. ; Sanchez, P. ; Real, L.M. ; Guillén-Navarro, E. ; Ayuso, C. ; González-Neira, A. ; Riancho, J.A. ; Rojas-Martinez, A. ; Carracedo, A. ; Lapunzina, P.
Novel genes and sex differences in COVID-19 severity.Frank, D. ; Garnish, S.E. ; Sandow, J.J. ; Weir, A. ; Liu, L. ; Clayer, E. ; Meza, L. ; Rashidi, M. ; Cobbold, S.A. ; Scutts, S.R. ; Doerflinger, M. ; Anderton, H. ; Lawlor, K.E. ; Lalaoui, N. ; Kueh, A.J. ; Eng, V.V. ; Ambrose, R.L. ; Herold, M.J. ; Samson, A.L. ; Feltham, R. ; Murphy, J.M. ; Ebert, G. ; Pearson, J.S. ; Vince, J.E.
Ubiquitylation of RIPK3 beyond-the-RHIM can limit RIPK3 activity and cell death.Smith, S. ; Huang, W. ; Tiamani, K. ; Unterer, M. ; Khan Mirzaei, M. ; Deng, L.
Emerging technologies in the study of the virome.Mai, J. ; Stubbe, M. ; Hofmann, S. ; Masser, S. ; Dobner, T. ; Boutell, C. ; Groitl, P. ; Schreiner, S.
PML alternative splice products differentially regulate HAdV productive infection.Modak, M. ; Mattes, A.K. ; Reiss, D. ; Skronska-Wasek, W. ; Langlois, R. ; Sabarth, N. ; Konopitzky, R. ; Ramírez, F. ; Lehr, K. ; Mayr, T. ; Kind, D. ; Viollet, C. ; Swee, L.K. ; Petschenka, J. ; El Kasmi, K.C. ; Nößner, E. ; Kitt, K. ; Pflanz, S.
CD206+ tumor-associated macrophages cross-present tumor antigen and drive anti-tumor immunity.Chen, W. ; Ma, J. ; Jiang, Y. ; Deng, L. ; Lv, N. ; Gao, J. ; Cheng, J. ; Liang, J.B. ; Wang, Y. ; Lan, T. ; Liao, X. ; Mi, J.
Selective maternal seeding and rearing environment from birth to weaning shape the developing piglet gut microbiome.Bohnacker, S. ; Hartung, F. ; Henkel, F. ; Quaranta, A. ; Kolmert, J. ; Priller, A. ; Ud-Dean, M. ; Giglberger, J. ; Kugler, L.M. ; Pechtold, L. ; Yazici, S. ; Lechner, A. ; Erber, J. ; Protzer, U. ; Lingor, P. ; Knolle, P. ; Chaker, A. ; Schmidt-Weber, C.B. ; Wheelock, C.E. ; Esser-von Bieren, J.
Correction to: Mild COVID-19 imprints a long-term inflammatory eicosanoid- and chemokine memory in monocyte-derived macrophages.Wenzel, M. ; Afzali, A.M. ; Hoffmann, D. ; Zange, S. ; Georgi, E. ; Hemmer, B.
Toskana-Virus-Meningoenzephalitis in Oberbayern.Duong, N.T. ; Dinh, T.H. ; Möhl, B.S. ; Hintze, S. ; Quynh, D.H. ; Ha, D.T.T. ; Ngoc, N.D. ; Dung, V.C. ; Miyake, N. ; Hai, N.V. ; Matsumoto, N. ; Meinke, P.
Cockayne syndrome without UV-sensitivity in Vietnamese siblings with novel ERCC8 variants.Liu, H. ; Bergant, V. ; Frishman, G. ; Ruepp, A. ; Pichlmair, A. ; Vincendeau, M. ; Frishman, D.
Influenza A virus infection reactivates human endogenous retroviruses associated with modulation of antiviral immunity.Sailer, N. ; Fetzer, I. ; Salvermoser, M. ; Braun, M. ; Brechtefeld, D. ; Krendl, C. ; Geiger, C. ; Mutze, K. ; Nößner, E. ; Schendel, D.J. ; Bürdek, M. ; Wilde, S. ; Sommermeyer, D.
T-cells expressing a highly potent PRAME-specific T-cell receptor in combination with a chimeric PD1-41BB co-stimulatory receptor show a favorable preclinical safety profile and strong anti-tumor reactivity.Kim, E.S. ; Zhou, J. ; Zhang, H. ; Marchetti, A. ; van de Klundert, M. ; Cai, D. ; Yu, X. ; Mitra, B. ; Liu, Y. ; Wang, M. ; Protzer, U. ; Guo, H.
Hepatitis B virus X protein counteracts high mobility group box 1 protein-mediated epigenetic silencing of covalently closed circular DNA.Kramvis, A. ; Chang, K.M. ; Dandri, M. ; Farci, P. ; Glebe, D. ; Hu, J. ; Janssen, H.L.A. ; Lau, D.T.Y. ; Penicaud, C. ; Pollicino, T. ; Testoni, B. ; Van Bömmel, F. ; Andrisani, O. ; Beumont-Mauviel, M. ; Block, T.M. ; Chan, H.L.Y. ; Cloherty, G.A. ; Delaney, W.E. ; Geretti, A.M. ; Gehring, A. ; Jackson, K. ; Lenz, O. ; Maini, M.K. ; Miller, V. ; Protzer, U. ; Yang, J.C. ; Yuen, M.F. ; Zoulim, F. ; Revill, P.A.
A roadmap for serum biomarkers for hepatitis B virus: Current status and future outlook.Padmanabhan Nair, V. ; Mayer, J. ; Vincendeau, M.
A protocol for CRISPR-mediated activation and repression of human endogenous retroviruses in human pluripotent stem cells.Meng, Z. ; Liu, J. ; Kosinska, A. ; Lu, M.
Editorial: Targeting the immune system to treat hepatitis B virus infection.Bunse, T. ; Kosinska, A. ; Michler, T. ; Protzer, U.
PD-L1 silencing in liver using siRNAs enhances efficacy of therapeutic vaccination for chronic hepatitis B.Bohnacker, S. ; Hartung, F. ; Henkel, F. ; Quaranta, A. ; Kolmert, J. ; Priller, A. ; Ud-Dean, M. ; Giglberger, J. ; Kugler, L.M. ; Pechtold, L. ; Yazici, S. ; Lechner, A. ; Erber, J. ; Protzer, U. ; Lingor, P. ; Knolle, P. ; Chaker, A. ; Schmidt-Weber, C.B. ; Wheelock, C.E. ; Esser-von Bieren, J.
Mild COVID-19 imprints a long-term inflammatory eicosanoid- and chemokine memory in monocyte-derived macrophages.Biswas, S. ; Rust, L.N. ; Wettengel, J.M. ; Yusova, S. ; Fischer, M. ; Carson, J.N. ; Johnson, J. ; Wei, L. ; Thode, T. ; Kaadige, M.R. ; Sharma, S. ; Agbaria, M. ; Bimber, B.N. ; Tu, T. ; Protzer, U. ; Ploss, A. ; Smedley, J.V. ; Golomb, G. ; Sacha, J.B. ; Burwitz, B.J.
Long-term hepatitis B virus infection of rhesus macaques requires suppression of host immunity.Tiamani, K. ; Luo, S. ; Schulz, S. ; Xue, J. ; Costa, R. ; Mirzaei, M.K. ; Deng, L.
The role of virome in the gastrointestinal tract and beyond.Käsmann, L. ; Taugner, J. ; Eze, C. ; Nieto, A. ; Pelikan, C. ; Floersch, B. ; Kenndoff, S. ; Hofer, T.P. ; Nößner, E. ; Schulz, C. ; Unterrainer, M. ; Tufman, A. ; Klauschen, F. ; Jung, A. ; Neumann, J. ; Kumbrink, J. ; Reinmuth, N. ; Bartenstein, P. ; Belka, C. ; Manapov, F.
Prospective evaluation of immunological, molecular-genetic, image-based and microbial analyses to characterize tumor response and control in patients with unresectable stage III NSCLC treated with concurrent chemoradiotherapy followed by consolidation therapy with durvalumab (PRECISION): Protocol for a prospective longitudinal biomarker study.Habermann, D. ; Kharimzadeh, H. ; Walker, A. ; Li, Y. ; Yang, R. ; Kaiser, R. ; Brumme, Z.L. ; Timm, J. ; Roggendorf, M. ; Hoffmann, D.
HAMdetector: A Bayesian regression model that integrates information to detect HLA-associated mutations.Essien, E.I. ; Hofer, T.P. ; Atkinson, M.J. ; Anastasov, N.
Combining HDAC and MEK inhibitors with radiation against glioblastoma-derived spheres.Schult, D. ; Reitmeier, S. ; Koyumdzhieva, P. ; Lahmer, T. ; Middelhof, M. ; Erber, J. ; Schneider, J. ; Kager, J. ; Frolova, M. ; Horstmann, J. ; Fricke, L. ; Steiger, K. ; Jesinghaus, M. ; Janssen, K.P. ; Protzer, U. ; Neuhaus, K. ; Schmid, R.M. ; Haller, D. ; Quante, M.
Gut bacterial dysbiosis and instability is associated with the onset of complications and mortality in COVID-19.Jakwerth, C.A. ; Feuerherd, M. ; Guerth, F. ; Oelsner, M. ; Schellhammer, L. ; Giglberger, J. ; Pechtold, L. ; Jerin, C. ; Kugler, L. ; Mogler, C. ; Haller, B. ; Erb, A. ; Wollenberg, B. ; Spinner, C.D. ; Buch, T. ; Protzer, U. ; Schmidt-Weber, C.B. ; Zissler, U.M. ; Chaker, A.
Early reduction of SARS-CoV-2-replication in bronchial epithelium by kinin B2 receptor antagonism.Klüpfel, J. ; Paßreiter, S. ; Weidlein, N. ; Knopp, M. ; Ungerer, M. ; Protzer, U. ; Knolle, P. ; Hayden, O. ; Elsner, M. ; Seidel, M.
Fully automated chemiluminescence microarray analysis platform for rapid and multiplexed. SARS-CoV-2 serodiagnostics.Ryu, J. ; Chan, W. ; Wettengel, J.M. ; Hanna, C.B. ; Burwitz, B.J. ; Hennebold, J.D. ; Bimber, B.N.
Rapid, accurate mapping of transgene integration in viable rhesus macaque embryos using enhanced-specificity tagmentation-assisted PCR.Luedemann, M. ; Stadler, D. ; Cheng, C.C. ; Protzer, U. ; Knolle, P.A. ; Donakonda, S.
Montelukast is a dual-purpose inhibitor of SARS-CoV-2 infection and virus-induced IL-6 expression identified by structure-based drug repurposing.Malin, J.J. ; Bunse, T. ; Spinner, C.D. ; Protzer, U.
Antivirale Medikamente.Potente Wirkstoffe, Hoffnungsträger bei COVID‑19 und therapeutische Grenzen.Bauer, A. ; Brack-Werner, R.
Modeling HIV latency in astrocytes with the human neural progenitor cell line HNSC.100.Baldassi, D. ; Ambike, S. ; Feuerherd, M. ; Cheng, C.-C. ; Peeler, D.J. ; Feldmann, D.P. ; Porras-Gonzalez, D.L. ; Wei, X. ; Keller, L.A. ; Kneidinger, N. ; Stoleriu, M.G. ; Popp, A. ; Burgstaller, G. ; Pun, S.H. ; Michler, T. ; Merkel, O.M.
Inhibition of SARS-CoV-2 replication in the lung with siRNA/VIPER polyplexes.Bauer, A. ; Puglisi, M. ; Nagl, D. ; Schick, J. ; Werner, T. ; Klingl, A. ; El Andari, J. ; Hornung, V. ; Kessler, H. ; Götz, M. ; Grimm, D. ; Brack-Werner, R.
Molecular signature of astrocytes for gene delivery by the synthetic adeno-associated viral vector rAAV9P1.Eumorphia Consortium (Hrabě de Angelis, M. ; Wurst, W. ; Abe, K. ; Beckers, J. ; Busch, D.H. ; Dalke, C. ; Gailus-Durner, V. ; Fuchs, H. ; Graw, J. ; Hölter, S.M. ; Kallnik, M. ; Lengger, C. ; Pedersen, V. ; Puk, O. ; Vogt Weisenhorn, D.M. ; Wagner, S.) ; Quintanilla-Fend, L.
EMPReSS: Standardized phenotype screens for functional annotation of the mouse genome (vol 37, pg 1155, 2005).Malehmir, M. ; Pfister, D. ; Gallage, S. ; Szydlowska, M. ; Inverso, D. ; Kotsiliti, E. ; Leone, V. ; Peiseler, M. ; Surewaard, B.G.J. ; Rath, D. ; Ali, A. ; Wolf, M.J. ; Drescher, H. ; Healy, M.E. ; Dauch, D. ; Kroy, D. ; Krenkel, O. ; Kohlhepp, M. ; Engleitner, T. ; Olkus, A. ; Sijmonsma, T. ; Volz, J. ; Deppermann, C. ; Stegner, D. ; Helbling, P. ; Nombela-Arrieta, C. ; Rafiei, A. ; Hinterleitner, M. ; Rall, M. ; Baku, F. ; Borst, O. ; Wilson, C.L. ; Leslie, J. ; O'Connor, T. ; Weston, C.J. ; Chauhan, A. ; Adams, D.H. ; Sheriff, L. ; Teijeiro, A. ; Prinz, M. ; Bogeska, R. ; Anstee, N. ; Bongers, M.N. ; Notohamiprodjo, M. ; Geisler, T. ; Withers, D.J. ; Ware, J. ; Mann, D.A. ; Augustin, H.G. ; Vegiopoulos, A. ; Milsom, M.D. ; Rose, A.J. ; Lalor, P.F. ; Llovet, J.M. ; Pinyol, R. ; Tacke, F. ; Rad, R. ; Matter, M. ; Djouder, N. ; Kubes, P. ; Knolle, P.A. ; Unger, K. ; Zender, L. ; Nieswandt, B. ; Gawaz, M. ; Weber, A. ; Heikenwälder, M.
Author Correction: Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer.Wratil, P.R. ; Stern, M. ; Priller, A. ; Willmann, A. ; Almanzar, G. ; Vogel, E. ; Feuerherd, M. ; Cheng, C.-C. ; Yazici, S. ; Christa, C. ; Jeske, S. ; Lupoli, G. ; Vogt, T. ; Albanese, M. ; Mejias-Perez, E. ; Bauernfried, S. ; Graf, N. ; Mijočević, H. ; Vu, M. ; Tinnefeld, K. ; Wettengel, J.M. ; Hoffmann, D. ; Muenchhoff, M. ; Daechert, C. ; Mairhofer, H. ; Krebs, S. ; Fingerle, V. ; Graf, A. ; Steininger, P. ; Blum, H. ; Hornung, V. ; Liebl, B. ; Überla, K. ; Prelog, M. ; Knolle, P. ; Keppler, O.T. ; Protzer, U.
Three exposures to the spike protein of SARS-CoV-2 by either infection or vaccination elicit superior neutralizing immunity to all variants of concern.Jakobsson, J. ; Vincendeau, M.
SnapShot: Human endogenous retroviruses.Körber, N. ; Priller, A. ; Yazici, S. ; Bauer, T. ; Cheng, C.-C. ; Mijočević, H. ; Wintersteller, H. ; Jeske, S. ; Vogel, E. ; Feuerherd, M. ; Tinnefeld, K. ; Winter, C. ; Ruland, J. ; Gerhard, M. ; Haller, B. ; Christa, C. ; Zelger, O. ; Roggendorf, H. ; Halle, M. ; Erber, J. ; Lingor, P. ; Keppler, O. ; Zehn, D. ; Protzer, U. ; Knolle, P.A.
Dynamics of spike-and nucleocapsid specific immunity during long-term follow-up and vaccination of SARS-CoV-2 convalescents.Fallerini, C. ; Picchiotti, N. ; Baldassarri, M. ; Zguro, K. ; Daga, S. ; Fava, F. ; Benetti, E. ; Amitrano, S. ; Bruttini, M. ; Palmieri, M.C. ; Croci, S. ; Lista, M. ; Beligni, G. ; Valentino, F. ; Meloni, I. ; Tanfoni, M. ; Minnai, F. ; Colombo, F. ; Cabri, E. ; Fratelli, M. ; Gabbi, C. ; Mantovani, S. ; Frullanti, E. ; Gori, M. ; Crawley, F.P. ; Butler-Laporte, G. ; Richards, B. ; Zeberg, H. ; Lipcsey, M. ; Hultström, M. ; Ludwig, K.U. ; Schulte, E.C. ; Pairo-Castineira, E. ; Baillie, J.K. ; Schmidt, A. ; Frithiof, R. ; GEN-COVID Multicenter Study (Protzer, U.) ; Mari, F. ; Renieri, A. ; Furini, S.
Common, low-frequency, rare, and ultra-rare coding variants contribute to COVID-19 severity.Ambike, S. ; Cheng, C.-C. ; Feuerherd, M. ; Velkov, S. ; Baldassi, D. ; Afridi, S.Q. ; Porras-Gonzalez, D.L. ; Wei, X. ; Hagen, P. ; Kneidinger, N. ; Stoleriu, M.G. ; Grass, V. ; Burgstaller, G. ; Pichlmair, A. ; Merkel, O.M. ; Ko, C. ; Michler, T.
Targeting genomic SARS-CoV-2 RNA with siRNAs allows efficient inhibition of viral replication and spread.Würstle, S. ; Erber, J. ; Hanselmann, M. ; Hoffmann, D. ; Werfel, S. ; Hering, S. ; Weidlich, S. ; Schneider, J. ; Franke, R. ; Maier, M. ; Henkel, A. ; Schmid, R.M. ; Protzer, U. ; Laxy, M. ; Spinner, C.D.
A telemedicine-guided self-collection approach for PCR-based SARS-CoV-2 testing: Comparative study.Grohmann, C. ; Marapana, D.S. ; Ebert, G.
Targeted protein degradation at the host-pathogen interface.Ganesan, M. ; Wang, W. ; Mathews, S. ; Makarov, E. ; New-Aaron, M. ; Dagur, R.S. ; Malo, A. ; Protzer, U. ; Kharbanda, K.K. ; Casey, C.A. ; Poluektova, L.Y. ; Osna, N.A.
Ethanol attenuates presentation of cytotoxic T-lymphocyte epitopes on hepatocytes of HBV-infected humanized mice.Speth, P. ; Jargosch, M. ; Seiringer, P. ; Schwamborn, K. ; Bauer, T. ; Scheerer, C. ; Protzer, U. ; Schmidt-Weber, C.B. ; Biedermann, T. ; Eyerich, S. ; Garzorz-Stark, N.
Immunocompromised patients with therapy-refractory chronic skin diseases show reactivation of latent EBV and CMV infection.Khan Mirzaei, M. ; Deng, L.
New technologies for developing phage-based tools to manipulate the human microbiome.Graf, S. ; Engelmann, L. ; Jeleff Wölfler, O. ; Albrecht, I. ; Schloderer, M. ; Kramer, A. ; Klankermayer, L. ; Gebhardt, F. ; Chaker, A.M. ; Spinner, C.D. ; Schwab, R. ; Wollenberg, B. ; Protzer, U. ; Hoffmann, D.
Reopening the Bavarian state opera safely: Hygiene strategies and incidence of COVID-19 in artistic staff during theater season 2020/2021.COVID-19 Host Genetics Initiative (Schulte, E.C.)
Mapping the human genetic architecture of COVID-19.Grunewald, C.M. ; Haist, C. ; König, C. ; Petzsch, P. ; Bister, A. ; Nößner, E. ; Wiek, C. ; Scheckenbach, K. ; Köhrer, K. ; Niegisch, G. ; Hanenberg, H. ; Hoffmann, M.J.
Epigenetic priming of bladder cancer cells with decitabine increases cytotoxicity of human EGFR and CD44v6 CAR engineered T-cells.Mancini, M. ; Righetto, M. ; Nößner, E.
Checkpoint inhibition in bladder cancer: Clinical expectations, current evidence, and proposal of future strategies based on a tumor-specific immunobiological approach.Olguín-Contreras, L.F. ; Mendler, A.N. ; Popowicz, G.M. ; Hu, B. ; Nößner, E.
Double strike approach for tumor attack: Engineering T cells using a CD40L:CD28 chimeric co-stimulatory switch protein for enhanced tumor targeting in adoptive cell therapy.Abdulhaqq, S. ; Ventura, A.B. ; Reed, J.S. ; Bashirova, A.A. ; Bateman, K.B. ; McDonald, E. ; Wu, H.L. ; Greene, J.M. ; Schell, J.B. ; Morrow, D. ; Wisskirchen, K. ; Martin, J.N. ; Deeks, S.G. ; Carrington, M.N. ; Protzer, U. ; Früh, K. ; Hansen, S.G. ; Picker, L.J. ; Sacha, J.B. ; Bimber, B.N.
Identification and characterization of antigen-specific CD8+ T cells using surface-trapped TNF-α and single-cell sequencing.Altstetter, S. ; Quitt, O. ; Pinci, F. ; Hornung, V. ; Lucko, A.M. ; Wisskirchen, K. ; Jung, S. ; Protzer, U.
Hepatitis-D virus infection is not impaired by innate immunity but increases cytotoxic T-cell activity.Svilenov, H.L. ; Sacherl, J. ; Reiter, A. ; Wolff, L.S. ; Cheng, C.-C. ; Stern, M. ; Grass, V. ; Feuerherd, M. ; Wachs, F.P. ; Simonavicius, N. ; Pippig, S. ; Wolschin, F. ; Keppler, O.T. ; Buchner, J. ; Brockmeyer, C. ; Protzer, U.
Picomolar inhibition of SARS-CoV-2 variants of concern by an engineered ACE2-IgG4-Fc fusion protein.Schreiber, S. ; Honz, M. ; Mamozai, W. ; Kurktschiev, P. ; Schiemann, M. ; Witter, K. ; Moore, E. ; Zielinski, C. ; Sette, A. ; Protzer, U. ; Wisskirchen, K.
Characterization of a library of 20 HBV-specific MHC class II-restricted T cell receptors.Heilbronner, U. ; Streit, F. ; Vogl, T. ; Senner, F. ; Schaupp, S.K. ; Reich-Erkelenz, D. ; Papiol, S. ; Oraki Kohshour, M. ; Klöhn-Saghatolislam, F. ; Kalman, J.L. ; Heilbronner, M. ; Gade, K. ; Comes, A.L. ; Budde, M. ; Andlauer, T.F.M. ; Anderson-Schmidt, H. ; Adorjan, K. ; Stürmer, T. ; Loerbroks, A. ; Amelang, M. ; Poisel, E. ; Foo, J.C. ; Heilmann-Heimbach, S. ; Forstner, A.J. ; Degenhardt, F. ; Zimmermann, J. ; Wiltfang, J. ; von Hagen, M. ; Spitzer, C. ; Schmauss, M. ; Reininghaus, E. ; Reimer, J. ; Konrad, C. ; Juckel, G. ; Lang, F.U. ; Jäger, M. ; Figge, C. ; Fallgatter, A.J. ; Dietrich, D.E. ; Dannlowski, U. ; Baune, B.T. ; Arolt, V. ; Anghelescu, I.G. ; Nöthen, M.M. ; Witt, S.H. ; Andreassen, O.A. ; Chen, C.H. ; Falkai, P. ; Rietschel, M. ; Schulze, T.G. ; Schulte, E.C.
Interplay between the genetics of personality traits, severe psychiatric disorders and COVID-19 host genetics in the susceptibility to SARS-CoV-2 infection.Svilenov, H.L. ; Sacherl, J. ; Protzer, U. ; Zacharias, M. ; Buchner, J.
Mechanistic principles of an ultra-long bovine CDR reveal strategies for antibody design.Zhao, L. ; Chen, F. ; Quitt, O. ; Festag, M. ; Ringelhan, M. ; Wisskirchen, K. ; Festag, J. ; Yakovleva, L. ; Sureau, C. ; Bohne, F. ; Aichler, M. ; Bruss, V. ; Shevtsov, M. ; van de Klundert, M. ; Momburg, F. ; Möhl, B.S. ; Protzer, U.
Hepatitis B virus envelope proteins can serve as therapeutic targets embedded in the host cell plasma membrane.Faure-Dupuy, S. ; Riedl, T. ; Rolland, M. ; Hizir, Z. ; Reisinger, F. ; Neuhaus, K. ; Schuehle, S. ; Remouchamps, C. ; Gillet, N. ; Schönung, M. ; Stadler, M. ; Wettengel, J.M. ; Barnault, R. ; Parent, R. ; Schuster, L.C. ; Farhat, R. ; Prokosch, S. ; Leuchtenberger, C. ; Öllinger, R. ; Engleitner, T. ; Rippe, K. ; Rad, R. ; Unger, K. ; Tscharahganeh, D. ; Lipka, D.B. ; Protzer, U. ; Durantel, D. ; Lucifora, J. ; Dejardin, E. ; Heikenwälder, M.
Control of APOBEC3B induction and cccDNA decay by NF-κB and miR-138-5p.Mastalerz, M. ; Dick, E. ; Chakraborty, A. ; Hennen, E. ; Schamberger, A.C. ; Schröppel, A. ; Lindner, M. ; Hatz, R.A. ; Behr, J. ; Hilgendorff, A. ; Schmid, O. ; Staab-Weijnitz, C.A.
Validation of in vitro models for smoke exposure of primary human bronchial epithelial cells.Auffray, C. ; Balling, R. ; Blomberg, N. ; Bonaldo, M.C. ; Boutron, B. ; Brahmachari, S. ; Bréchot, C. ; Cesario, A. ; Chen, S.J. ; Clément, K. ; Danilenko, D. ; Meglio, A.D. ; Gelemanović, A. ; Goble, C. ; Gojobori, T. ; Goldman, J.D. ; Goldman, M. ; Guo, Y.K. ; Heath, J. ; Hood, L. ; Hunter, P. ; Jin, L. ; Kitano, H. ; Knoppers, B.M. ; Lancet, D. ; Larue, C. ; Lathrop, M. ; Laville, M. ; Lindner, A.B. ; Magnan, A. ; Metspalu, A. ; Morin, E. ; Ng, L.F.P. ; Nicod, L. ; Noble, D. ; Nottale, L. ; Nowotny, H. ; Ochoa, T. ; Okeke, I.N. ; Oni, T. ; Openshaw, P. ; Öztürk, M. ; Palkonen, S. ; Paweska, J.T. ; Pison, C. ; Polymeropoulos, M.H. ; Pristipino, C. ; Protzer, U. ; Roca, J. ; Rozman, D. ; Santolini, M. ; Sanz, F. ; Scambia, G. ; Segal, E. ; Serageldin, I. ; Soares, M.B. ; Sterk, P. ; Sugano, S. ; Superti-Furga, G. ; Supple, D. ; Tegnér, J. ; Uhlén, M. ; Urbani, A. ; Valencia, A. ; Valentini, V. ; van der Werf, S. ; Vinciguerra, M. ; Wolkenhauer, O. ; Wouters, E.
COVID-19 and beyond: A call for action and audacious solidarity to all the citizens and nations, it is humanity’s fight.Klopp, A. ; Schreiber, S. ; Kosinska, A. ; Pulé, M. ; Protzer, U. ; Wisskirchen, K.
Depletion of T cells via inducible caspase 9 increases safety of adoptive T-cell therapy against chronic hepatitis B.Feuerherd, M. ; Sippel, A.K. ; Erber, J. ; Baumbach, J.I. ; Schmid, R.M. ; Protzer, U. ; Voit, F. ; Spinner, C.D.
A proof of concept study for the differentiation of SARS-CoV-2, hCoV-NL63, and IAV-H1N1 in vitro cultures using ion mobility spectrometry.Oswald, A. ; Chakraborty, A. ; Ni, Y. ; Wettengel, J.M. ; Urban, S. ; Protzer, U.
Concentration of Na+-taurocholate-cotransporting polypeptide expressed after in vitro-transcribed mRNA transfection determines susceptibility of hepatoma cells for hepatitis B virus.Nakanishi, T. ; Pigazzini, S. ; Degenhardt, F. ; Cordioli, M. ; Butler-Laporte, G. ; Maya-Miles, D. ; Bujanda, L. ; Bouysran, Y. ; Niemi, M.E. ; Palom, A. ; Ellinghaus, D. ; Khan, A. ; Martínez-Bueno, M. ; Rolker, S. ; Amitrano, S. ; Roade Tato, L. ; Fava, F. ; Spinner, C.D. ; Prati, D. ; Bernardo, D. ; Garcia, F. ; Darcis, G. ; Fernandez-Cadenas, I. ; Holter, J.C. ; Banales, J.M. ; Frithiof, R. ; Kiryluk, K. ; Duga, S. ; Asselta, R. ; Pereira, A.C. ; Romero-Gómez, M. ; Nafría-Jiménez, B. ; Hov, J.R. ; Migeotte, I. ; Renieri, A. ; Planas, A.M. ; Ludwig, K.U. ; Buti, M. ; Rahmouni, S. ; Alarcón-Riquelme, M.E. ; Schulte, E.C. ; Franke, A. ; Karlsen, T.H. ; Valenti, L. ; Zeberg, H. ; Richards, J.B. ; Ganna, A.
Age-dependent impact of the major common genetic risk factor for COVID-19 on severity and mortality.Körber, N. ; Pohl, L. ; Weinberger, B. ; Grubeck-Loebenstein, B. ; Wawer, A. ; Knolle, P.A. ; Roggendorf, H. ; Protzer, U. ; Bauer, T.
Hepatitis B vaccine non-responders show higher frequencies of CD24highCD38high regulatory B cells and lower levels of IL-10 expression compared to responders.Schmitz, T. ; Hoffmann, V. ; Olliges, E. ; Bobinger, A. ; Popovici, R. ; Nößner, E. ; Meissner, K.
Reduced frequency of perforin-positive CD8+ T cells in menstrual effluent of endometriosis patients.Schulte, E.C. ; Sellner, J.
SARS-CoV-2 vaccination in multiple sclerosis: A clearer picture for the time point during CD20 depleting therapy.Issels, R.D. ; Nößner, E. ; Lindner, L.H. ; Schmidt, M. ; Albertsmeier, M. ; Blay, J.Y. ; Stutz, E. ; Xu, Y. ; Buecklein, V. ; Altendorf-Hofmann, A. ; Abdel-Rahman, S. ; Mansmann, U. ; von Bergwelt-Baildon, M. ; Knoesel, T.
Immune infiltrates in patients with localised high-risk soft tissue sarcoma treated with neoadjuvant chemotherapy without or with regional hyperthermia: A translational research program of the EORTC 62961-ESHO 95 randomised clinical trial.Luckow, B. ; Lehmann, M.H.
A simplified method for bronchoalveolar lavage in mice by orotracheal intubation avoiding tracheotomy.Walter, N. ; Deng, L. ; Brochhausen, C. ; Alt, V. ; Rupp, M.
Behandlung von Knochen- und Protheseninfektionen mit Bakteriophagen.Ein systematisches Review.Chu, C.F. ; Sabath, F. ; Fibi-Smetana, S. ; Sun, S. ; Öllinger, R. ; Nößner, E. ; Chao, Y.Y. ; Rinke, L.L. ; Winheim, E. ; Rad, R. ; Krug, A.B. ; Taher, L. ; Zielinski, C.E.
Convalescent COVID-19 patients without comorbidities display similar immunophenotypes over time despite divergent disease severities.Froeschl, G. ; Hoelscher, M. ; Maganga, L.H. ; Kroidl, I. ; Clowes, P. ; Geis, S. ; Saathoff, E. ; Hoffmann, D. ; Protzer, U. ; Kroidl, A.
Hepatitis B, C and D virus prevalence in children and adults in Mbeya Region, Tanzania: Results from a cohort study 2002-2009.Gassmann, H. ; Schneider, K. ; Evdokimova, V. ; Ruzanov, P. ; Schober, S.J. ; Xue, B. ; von Heyking, K. ; Thiede, M. ; Richter, G.H.S. ; Pfaffl, M.W. ; Nössner, E. ; Stein, L.D. ; Sorensen, P.H.B. ; Thiel, U.
Ewing sarcoma-derived extracellular vesicles impair dendritic cell maturation and function.Osterman, A. ; Iglhaut, M. ; Lehner, A. ; Späth, P. ; Stern, M. ; Autenrieth, H. ; Muenchhoff, M. ; Graf, A. ; Krebs, S. ; Blum, H. ; Baiker, A. ; Grzimek-Koschewa, N. ; Protzer, U. ; Kaderali, L. ; Baldauf, H.M. ; Keppler, O.T.
Comparison of four commercial, automated antigen tests to detect SARS-CoV-2 variants of concern.Kosinska, A. ; Festag, J. ; Mück-Häusl, M. ; Festag, M. ; Asen, T. ; Protzer, U.
Immunogenicity and antiviral response of therapeutic hepatitis B vaccination in a mouse model of hbeag-negative, persistent hbv infection.Wettengel, J.M. ; Linden, B. ; Esser, K. ; Laue, M. ; Burwitz, B.J. ; Protzer, U.
Rapid and robust continuous purification of high-titer hepatitis B virus for in vitro and in vivo applications.Ma, T. ; Ru, J. ; Xue, J. ; Schulz, S. ; Mirzaei, M.K. ; Janssen, K.P. ; Quante, M. ; Deng, L.
Differences in gut virome related to barrett esophagus and esophageal adenocarcinoma.Tenbusch, M. ; Schumacher, S. ; Vogel, E. ; Priller, A. ; Held, J. ; Steininger, P. ; Beileke, S. ; Irrgang, P. ; Brockhoff, R. ; Salmanton-García, J. ; Tinnefeld, K. ; Mijočević, H. ; Schober, K. ; Bogdan, C. ; Yazici, S. ; Knolle, P. ; Cornely, O.A. ; Überla, K. ; Protzer, U.
Heterologous prime-boost vaccination with ChAdOx1 nCoV-19 and BNT162b2.Fischer, D.S. ; Ansari, M. ; Wagner, K.I. ; Jarosch, S. ; Huang, Y. ; Mayr, C. ; Strunz, M. ; Lang, N.J. ; D'Ippolito, E. ; Hammel, M. ; Mateyka, L. ; Weber, S. ; Wolff, L.S. ; Witter, K. ; Fernandez, I.E. ; Leuschner, G. ; Milger, K. ; Frankenberger, M. ; Nowak, L. ; Heinig-Menhard, K. ; Koch, I. ; Stoleriu, M.-G. ; Hilgendorff, A. ; Behr, J. ; Pichlmair, A. ; Schubert, B. ; Theis, F.J. ; Busch, D.H. ; Schiller, H. B. ; Schober, K.
Single-cell RNA sequencing reveals ex vivo signatures of SARS-CoV-2-reactive T cells through 'reverse phenotyping'.O'Connor, T. ; Heikenwälder, M.
CCL2 in the tumor microenvironment.Gaitzsch, E. ; Passerini, V. ; Khatamzas, E. ; Strobl, C.D. ; Muenchhoff, M. ; Scherer, C. ; Osterman, A. ; Heide, M. ; Reischer, A. ; Subklewe, M. ; Leutbecher, A. ; Tast, B. ; Ruhle, A. ; Weiglein, T. ; Stecher, S.S. ; Stemmler, H.J. ; Dreyling, M. ; Girl, P. ; Georgi, E. ; Wölfel, R. ; Mateyka, L. ; D'Ippolito, E. ; Schober, K. ; Busch, D.H. ; Kager, J. ; Spinner, C.D. ; Treiber, M. ; Rasch, S. ; Lahmer, T. ; Iakoubov, R. ; Schneider, J. ; Protzer, U. ; Winter, C. ; Ruland, J. ; Quante, M. ; Keppler, O.T. ; von Bergwelt-Baildon, M. ; Hellmuth, J.C. ; Weigert, O.
COVID-19 in Patients Receiving CD20-depleting Immunochemotherapy for B-cell Lymphoma.Cornberg, M. ; Sandmann, L. ; Protzer, U. ; Niederau, C. ; Tacke, F. ; Berg, T. ; Glebe, D. ; Jilg, W. ; Wedemeyer, H. ; Wirth, S. ; Siederdissen, C.H.Z. ; Lynen-Jansen, P. ; Leeuwen, P. ; Petersen, J.
S3-Leitlinie der Deutschen Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS) zur Prophylaxe, Diagnostik und Therapie der Hepatitis-B-Virusinfektion.Teng, Y. ; Xu, Z. ; Zhao, K. ; Zhong, Y. ; Wang, J. ; Zhao, L. ; Zheng, Z. ; Hou, W. ; Zhu, C. ; Chen, X. ; Protzer, U. ; Li, Y. ; Xia, Y.
Novel function of SART1 in HNF4α transcriptional regulation contributes to its antiviral role during HBV infection.Ko, C. ; Su, J. ; Festag, J. ; Bester, R. ; Kosinska, A. ; Protzer, U.
Intramolecular recombination enables the formation of hepatitis B virus (HBV) cccDNA in mice after HBV genome transfer using recombinant AAV vectors.Zhang, D. ; Zhang, K. ; Protzer, U. ; Zeng, C.
HBV integration induces complex interactions between host and viral genomic functions at the insertion site.Huang, H. ; Jiang, Y. ; Zhao, J. ; Li, S. ; Schulz, S. ; Deng, L.
BTEX biodegradation is linked to bacterial community assembly patterns in contaminated groundwater ecosystem.Quitt, O. ; Luo, S. ; Meyer, M. ; Xie, Z. ; Golsaz-Shirazi, F. ; Loffredo-Verde, E. ; Festag, J. ; Bockmann, J.H. ; Zhao, L. ; Stadler, D. ; Chou, W.M. ; Tedjokusumo, R. ; Wettengel, J.M. ; Ko, C. ; Nößner, E. ; Bulbuc, N. ; Shokri, F. ; Lüttgau, S. ; Heikenwälder, M. ; Bohne, F. ; Moldenhauer, G. ; Momburg, F. ; Protzer, U.
T-cell engager antibodies enable T cells to control HBV infection and to target HBsAg-positive hepatoma in mice.Ramsheh, M.Y. ; Haldar, K. ; Esteve-Codina, A. ; Purser, L.F. ; Richardson, M. ; Müller-Quernheim, J. ; Greulich, T. ; Nowinski, A. ; Barta, I. ; Stendardo, M. ; Boschetto, P. ; Korzybski, D. ; Prasse, A. ; Parr, D.G. ; Hohlfeld, J.M. ; Döme, B. ; Welte, T. ; Heath, S. ; Gut, I. ; Morrissey, J.A. ; Ziegler-Heitbrock, L. ; Barer, M.R. ; Singh, D. ; Brightling, C.E.
Lung microbiome composition and bronchial epithelial gene expression in patients with COPD versus healthy individuals: A bacterial 16S rRNA gene sequencing and host transcriptomic analysis.Afridi, S.Q. ; Usman, Z. ; Donakonda, S. ; Wettengel, J.M. ; Velkov, S. ; Beck, R. ; Gerhard, M. ; Knolle, P. ; Frishman, D. ; Protzer, U. ; Moeini, H. ; Hoffmann, D.
Prolonged norovirus infections correlate to quasispecies evolution resulting in structural changes of surface-exposed epitopes.Holmen Olofsson, G. ; Idorn, M. ; Carnaz Simões, A.M. ; Aehnlich, P. ; Skadborg, S.K. ; Nößner, E. ; Debets, R. ; Moser, B. ; Met, Ö. ; Thor Straten, P.
Vγ9Vδ2 T cells concurrently kill cancer cells and cross-present tumor antigens.Schulte, E.C. ; Hauer, L. ; Kunz, A.B. ; Sellner, J.
Systematic review of cases of acute myelitis in individuals with COVID-19.Costa, R. ; Wagner, D.E. ; Doryab, A. ; De Santis, M.M. ; Schorpp, K.K. ; Rothenaigner, I. ; Lehmann, M. ; Baarsma, H.A. ; Liu, X. ; Schmid, O. ; Campillos, M.J. ; Yildirim, A.Ö. ; Hadian, K. ; Königshoff, M.
A drug screen with approved compounds identifies amlexanox as a novel Wnt/β-catenin activator inducing lung epithelial organoid formation.Unterer, M. ; Khan Mirzaei, M. ; Deng, L.
Gut phage database: Phage mining in the cave of wonders.Esteve-Codina, A. ; Hofer, T.P. ; Burggraf, D. ; Heiss-Neumann, M.S. ; Gesierich, W. ; Boland, A. ; Olaso, R. ; Bihoreau, M.T. ; Deleuze, J.F. ; Möller, W. ; Schmid, O. ; Soler Artigas, M. ; Renner, K. ; Hohlfeld, J.M. ; Welte, T. ; Fuehner, T. ; Jerrentrup, L. ; Koczulla, A.R. ; Greulich, T. ; Prasse, A. ; Müller-Quernheim, J. ; Gupta, S. ; Brightling, C. ; Subramanian, D.R. ; Parr, D.G. ; Kolsum, U. ; Gupta, V. ; Barta, I. ; Döme, B. ; Strausz, J. ; Stendardo, M. ; Piattella, M. ; Boschetto, P. ; Korzybski, D. ; Gorecka, D. ; Nowinski, A. ; Dabad, M. ; Fernández-Callejo, M. ; Endesfelder, D. ; zu Castell, W. ; Hiemstra, P.S. ; Venge, P. ; Nößner, E. ; Griebel, T. ; Heath, S. ; Singh, D. ; Gut, I. ; Ziegler-Heitbrock, L.
Gender specific airway gene expression in COPD sub-phenotypes supports a role of mitochondria and of different types of leukocytes.Klüpfel, J. ; Koros, R.C. ; Dehne, K. ; Ungerer, M. ; Würstle, S. ; Mautner, J. ; Feuerherd, M. ; Protzer, U. ; Hayden, O. ; Elsner, M. ; Seidel, M.
Automated, flow-based chemiluminescence microarray immunoassay for the rapid multiplex detection of IgG antibodies to SARS-CoV-2 in human serum and plasma (CoVRapid CL-MIA).Sigl, C. ; Willner, E.M. ; Engelen, W. ; Kretzmann, J.A. ; Sachenbacher, K. ; Liedl, A. ; Kolbe, F. ; Wilsch, F. ; Aghvami, S.A. ; Protzer, U. ; Hagan, M.F. ; Fraden, S. ; Dietz, H.
Programmable icosahedral shell system for virus trapping.Riedl, T. ; Faure-Dupuy, S. ; Rolland, M. ; Schuehle, S. ; Hizir, Z. ; Calderazzo, S. ; Zhuang, X. ; Wettengel, J.M. ; Lopez, M.A. ; Barnault, R. ; Mirakaj, V. ; Prokosch, S. ; Heide, D. ; Leuchtenbergeg, C. ; Schneider, M. ; Heßling, B. ; Stottmeier, B. ; Wessbecher, I.M. ; Schirmacher, P. ; McKeating, J.A. ; Protzer, U. ; Durantel, D. ; Lucifora, J. ; Dejardin, E. ; Heikenwalder, M.
HIF1α-mediated RelB/APOBEC3B downregulation allows Hepatitis B Virus persistence.Stadler, D. ; Kächele, M. ; Jones, A. ; Hess J. ; Urban, C. ; Schneider, J. ; Xia, Y. ; Oswald, A. ; Nebioglu, F. ; Bester, R. ; Lasitschka, F. ; Ringelhan, M. ; Ko, C. ; Chou, W.M. ; Geerlof, A. ; van de Klundert, M. ; Wettengel, J.M. ; Schirmacher, P. ; Heikenwälder, M. ; Schreiner, S. ; Bartenschlager, R. ; Pichlmair, A. ; Sattler, M. ; Unger, K. ; Protzer, U.
Interferon-induced degradation of the persistent hepatitis B virus cccDNA form depends on ISG20.Würstle, S. ; Spinner, C.D. ; Voit, F. ; Hoffmann, D. ; Hering, S. ; Weidlich, S. ; Schneider, J. ; Zink, A. ; Treiber, M. ; Iakoubov, R. ; Schmid, R.M. ; Protzer, U. ; Erber, J.
Self-sampling versus health care professional-guided swab collection for SARS-CoV-2 testing.Goettsch, W. ; Beerenwinkel, N. ; Deng, L. ; Dölken, L. ; Dutilh, B.E. ; Erhard, F. ; Kaderali, L. ; von Kleist, M. ; Marquet, R. ; Matthijnssens, J. ; McCallin, S. ; McMahon, D.P. ; Rattei, T. ; Van Rij, R.P. ; Robertson, D.L. ; Schwemmle, M. ; Stern-Ginossar, N. ; Marz, M.
ITN-VIROINF: Understanding (Harmful) virus-host interactions by linking virology and bioinformatics.Aghaee, B.L. ; Mirzaei, M.K. ; Alikhani, M.Y. ; Mojtahedi, A.
Sewage and sewage-contaminated environments are the most prominent sources to isolate phages against Pseudomonas aeruginosa.Appelman, M.D. ; Wettengel, J.M. ; Protzer, U. ; Oude Elferink, R.P.J. ; van de Graaf, S.F.J.
Molecular regulation of the hepatic bile acid uptake transporter and HBV entry receptor NTCP.Weber, M. ; Padmanabhan Nair, V. ; Bauer, T. ; Sprinzl, M.F. ; Protzer, U. ; Vincendeau, M.
Increased HERV-K(HML-2) transcript levels correlate with clinical parameters of liver damage in hepatitis C patients.Dudaniec, K. ; Westendorf, K. ; Nößner, E. ; Uckert, W.
Generation of Epstein-Barr virus antigen-specific T cell receptors recognizing immunodominant epitopes of LMP1, LMP2A, and EBNA3C for immunotherapy.Zhao, J.Y. ; Hu, B. ; Dolfing, J. ; Li, Y. ; Tang, Y.Q. ; Jiang, Y. ; Chi, C.Q. ; Xing, J. ; Nie, Y. ; Wu, X.L.
Thermodynamically favorable reactions shape the archaeal community affecting bacterial community assembly in oil reservoirs.Padmanabhan Nair, V. ; Liu, H. ; Ciceri, G. ; Jungverdorben, J. ; Frishman, G. ; Tchieu, J. ; Cederquist, G.Y. ; Rothenaigner, I. ; Schorpp, K.K. ; Klepper, L. ; Walsh, R.M. ; Kim, T.W. ; Cornacchia, D. ; Ruepp, A. ; Mayer, J. ; Hadian, K. ; Frishman, D. ; Studer, L. ; Vincendeau, M.
Activation of HERV-K(HML-2) disrupts cortical patterning and neuronal differentiation by increasing NTRK3.Pfister, D. ; Núñez, N.G. ; Pinyol, R. ; Govaere, O. ; Pinter, M. ; Szydlowska, M. ; Gupta, R. ; Qiu, M. ; Deczkowska, A. ; Weiner, A. ; Müller, F. ; Sinha, A. ; Friebel, E. ; Engleitner, T. ; Lenggenhager, D. ; Moncsek, A. ; Heide, D. ; Stirm, K. ; Kosla, J. ; Kotsiliti, E. ; Leone, V. ; Dudek, M. ; Yousuf, S. ; Inverso, D. ; Singh, I. ; Teijeiro, A. ; Castet, F. ; Montironi, C. ; Haber, P.K. ; Tiniakos, D. ; Bedossa, P. ; Cockell, S. ; Younes, R. ; Vacca, M. ; Marra, F. ; Schattenberg, J.M. ; Allison, M. ; Bugianesi, E. ; Ratziu, V. ; Pressiani, T. ; D'Alessio, A. ; Personeni, N. ; Rimassa, L. ; Daly, A.K. ; Scheiner, B. ; Pomej, K. ; Kirstein, M.M. ; Vogel, A. ; Peck-Radosavljevic, M. ; Hucke, F. ; Finkelmeier, F. ; Waidmann, O. ; Trojan, J. ; Schulze, K. ; Wege, H. ; Koch, S. ; Weinmann, A. ; Bueter, M. ; Rössler, F. ; Siebenhüner, A. ; Dosso, S. ; Mallm, J.P. ; Umansky, V. ; Jugold, M. ; Luedde, T. ; Schietinger, A. ; Schirmacher, P. ; Emu, B. ; Augustin, H.G. ; Billeter, A.T. ; Müller-Stich, B. ; Kikuchi, H. ; Duda, D.G. ; Kütting, F. ; Waldschmidt, D.T. ; Ebert, M.P. ; Rahbari, N. ; Mei, H.E. ; Schulz, A.R. ; Ringelhan, M. ; Malek, N. ; Spahn, S. ; Bitzer, M. ; Ruiz de Galarreta, M. ; Lujambio, A. ; Dufour, J.F. ; Marron, T.U. ; Kaseb, A. ; Kudo, M. ; Huang, Y.H. ; Djouder, N. ; Wolter, K. ; Zender, L. ; Marche, P.N. ; Decaens, T. ; Pinato, D.J. ; Rad, R. ; Mertens, J.C. ; Weber, A. ; Unger, K. ; Meissner, F. ; Roth, S. ; Jilkova, Z.M. ; Claassen, M. ; Anstee, Q.M. ; Amit, I. ; Knolle, P. ; Becher, B. ; Llovet, J.M. ; Heikenwalder, M.
NASH limits anti-tumour surveillance in immunotherapy-treated HCC.Conlon, T.M. ; John-Schuster, G. ; Heide, D. ; Pfister, D. ; Lehmann, M. ; Hu, Y. ; Ertüz, Z. ; López, M.A. ; Ansari, M. ; Strunz, M. ; Mayr, C. ; Angelidis, I. ; Ciminieri, C. ; Costa, R. ; Kohlhepp, M.S. ; Guillot, A. ; Güneş, G. ; Jeridi, A. ; Funk, M.C. ; Beroshvili, G. ; Prokosch, S. ; Hetzer, J. ; Verleden, S.E. ; Alsafadi, H.N. ; Lindner, M. ; Burgstaller, G. ; Becker, L. ; Irmler, M. ; Dudek, M. ; Janzen, J. ; Goffin, E. ; Gosens, R. ; Knolle, P. ; Pirotte, B. ; Stöger, T. ; Beckers, J. ; Wagner, D.E. ; Singh, I. ; Theis, F.J. ; Hrabě de Angelis, M. ; O’Connor, T. ; Tacke, F. ; Boutros, M. ; Dejardin, E. ; Eickelberg, O. ; Schiller, H. B. ; Königshoff, M. ; Heikenwalder, M. ; Yildirim, A.Ö.
Publisher Correction: Inhibition of LTβR signalling activates WNT-induced regeneration in lung (Nature, (2020), 588, 7836, (151-156), 10.1038/s41586-020-2882-8).Aghaee, B.L. ; Khan Mirzaei, M. ; Alikhani, M.Y. ; Mojtahedi, A. ; Maurice, C.F.
Improving the inhibitory effect of phages against Pseudomonas aeruginosa isolated from a burn patient using a combination of phages and antibiotics.Deschler, S. ; Kager, J. ; Erber, J. ; Fricke, L. ; Koyumdzhieva, P. ; Georgieva, A. ; Lahmer, T. ; Wiessner, J.R. ; Voit, F. ; Schneider, J. ; Horstmann, J. ; Iakoubov, R. ; Treiber, M. ; Winter, C. ; Ruland, J. ; Busch, D.H. ; Knolle, P.A. ; Protzer, U. ; Spinner, C.D. ; Schmid, R.M. ; Quante, M. ; Böttcher, K.
Mucosal-associated invariant T (MAIT) cells are highly activated and functionally impaired in COVID-19 patients.Bork, K. ; Wulff, K. ; Möhl, B.S. ; Steinmüller-Magin, L. ; Witzke, G. ; Hardt, J. ; Meinke, P.
Novel hereditary angioedema linked with a heparan sulfate 3-O-sulfotransferase 6 gene mutation.Wing, P.A. ; Liu, P.J. ; Harris, J.M. ; Magri, A. ; Michler, T. ; Zhuang, X. ; Borrmann, H. ; Minisini, R. ; Frampton, N.R. ; Wettengel, J.M. ; Mailly, L. ; D'Arienzo, V. ; Riedl, T. ; Nobre, L. ; Weekes, M.P. ; Pirisi, M. ; Heikenwalder, M. ; Baumert, T.F. ; Hammond, E.M. ; Mole, D.R. ; Protzer, U. ; Balfe, P. ; McKeating, J.A.
Hypoxia inducible factors regulate hepatitis B virus replication by activating the basal core promoter.Osterman, A. ; Baldauf, H. ; Eletreby, M. ; Wettengel, J.M. ; Afridi, S.Q. ; Fuchs, T. ; Holzmann, E. ; Maier, A. ; Doring, J. ; Grzimek-Koschewa, N. ; Muenchhoff, M. ; Protzer, U. ; Kaderali, L. ; Keppler, O.T.
Evaluation of two rapid antigen tests to detect SARS-CoV-2 in a hospital setting.Ma, Y. ; Bauer, V. ; Riedel, T. ; Ahmetlic, F. ; Hömberg, N. ; Hofer, T.P. ; Röcken, M. ; Mocikat, R.
Interleukin-10 counteracts T-helper type 1 responses in B-cell lymphoma and is a target for tumor immunotherapy.Hofmann, S. ; Stubbe, M. ; Mai, J. ; Schreiner, S.
Double-edged role of PML nuclear bodies during human adenovirus infection.Jiang, Y. ; Huang, H. ; Tian, Y. ; Yu, X. ; Li, X.
Stochasticity versus determinism: Microbial community assembly patterns under specific conditions in petrochemical activated sludge.Hippich, M. ; Holthaus, L. ; Assfalg, R. ; Zapardiel-Gonzalo, J. ; Kapfelsperger, H. ; Heigermoser, M. ; Haupt, F. ; Ewald, D.A. ; Welzhofer, T.C. ; Marcus, B.A. ; Heck, S. ; Koelln, A. ; Stock, J. ; Voss, F. ; Secchi, M. ; Piemonti, L. ; Rosa, K. ; Protzer, U. ; Boehmer, M. ; Achenbach, P. ; Lampasona, V. ; Bonifacio, E. ; Ziegler, A.-G.
Public health antibody screening indicates a six-fold higher SARS-CoV-2 exposure rate than reported cases in children.Khan Mirzaei, M. ; Deng, L.
Sustainable microbiome: A symphony orchestrated by synthetic phages.Khan Mirzaei, M. ; Xue, J. ; Costa, R. ; Ru, J. ; Schulz, S. ; Taranu, Z.E. ; Deng, L.
Challenges of studying the human virome – relevant emerging technologies.Jung, S. ; von Thülen, T. ; Yang, I. ; Laukemper, V. ; Rupf, B. ; Janga, H. ; Panagiotidis, G.-D. ; Schoen, A. ; Nicolai, M. ; Schulte, L.N. ; Obermann, H.-L. ; Weber, F. ; Kaufmann, A. ; Bauer, S.
A ribosomal RNA fragment with 2',3'-cyclic phosphate and GTP-binding activity acts as RIG-I ligand.Han, H. ; Huang, H. ; Li, X.
Current policies and policy implications for environmental pollution.Ling, Z. ; Jiang, Y. ; Li, X.
Gut remediation: Back to the future.Jiang, Y. ; Khan, A. ; Huang, H. ; Tian, Y. ; Yu, X. ; Xu, Q. ; Mou, L. ; Lv, J. ; Zhang, P. ; Liu, P. ; Deng, L. ; Li, X.
Corrigendum to “Using nano-attapulgite clay compounded hydrophilic urethane foams (AT/HUFs) as biofilm support enhances oil-refinery wastewater treatment in a biofilm membrane bioreactor” [Sci. Total Environ., 646 (2019) 606-17/STOTEN-D-18-03954] (Science of the Total Environment (2019) 646 (606–617), (S0048969718326354), (10.1016/j.scitotenv.2018.07.149)).Liu, P.J. ; Harris, J.M. ; Marchi, E. ; D’Arienzo, V. ; Michler, T. ; Wing, P.A.C. ; Magri, A. ; Ortega-Prieto, A.M. ; van de Klundert, M. ; Wettengel, J.M. ; Durantel, D. ; Dorner, M. ; Klenerman, P. ; Protzer, U. ; Giotis, E.S. ; McKeating, J.A.
Author Correction: Hypoxic gene expression in chronic hepatitis B virus infected patients is not observed in state-of-the-art in vitro and mouse infection models (Scientific Reports, (2020), 10, 1, (14101), 10.1038/s41598-020-70865-7).Yanchun, M. ; Bauer, V. ; Riedel, T. ; Hofer, T.P. ; Roecken, M. ; Mocikat, R.
Interleukin-10 drives the development of T regulatory type 1 (Tr1) cells and is a target for immunotherapy.Fischbeck, A. ; Ruehland, S. ; Ettinger, A. ; Paetzold, K. ; Masouris, I. ; Nößner, E. ; Mendler, A.N.
Tumor lactic acidosis: Protecting tumor by inhibiting cytotoxic activity through motility arrest and bioenergetic silencing.Jung, S. ; Jakobs, K.F.K. ; Shein, M. ; Schütz, A.K. ; Mohr, F. ; Stadler, H. ; Stadler, D. ; Lucko, A. ; Altstetter, S. ; Wilsch, F. ; Deng, L. ; Protzer, U.
Efficient and reproducible depletion of hepatitis B virus from plasma derived extracellular vesicles.Velkov, S. ; Protzer, U. ; Michler, T.
Global occurrence of clinically relevant hepatitis B virus variants as found by analysis of publicly available sequencing data.Kaletta, J. ; Pickl, C. ; Griebler, C. ; Klingl, A. ; Kurmayer, R. ; Deng, L.
A rigorous assessment and comparison of enumeration methods for environmental viruses.Lampl, S. ; Janas, M.K. ; Donakonda, S. ; Brugger, M. ; Lohr, K. ; Schneider, A. ; Manske, K. ; Sperl, L.E. ; Kläger, S. ; Küster, B. ; Wettmarshausen, J. ; Müller, C. ; Laschinger, M. ; Hartmann, D. ; Hüser, N. ; Perocchi, F. ; Schmitt-Kopplin, P. ; Hagn, F. ; Zender, L. ; Hornung, V. ; Borner, C. ; Pichlmair, A. ; Kashkar, H. ; Klingenspor, M. ; Prinz, M. ; Schreiner, S. ; Conrad, M. ; Jost, P.J. ; Zischka, H. ; Steiger, K. ; Krönke, M. ; Zehn, D. ; Protzer, U. ; Heikenwälder, M. ; Knolle, P.A. ; Wohlleber, D.
Reduced mitochondrial resilience enables non-canonical induction of apoptosis after TNF receptor signaling in virus-infected hepatocytes.Heger, L. ; Hofer, T.P. ; Bigley, V. ; de Vries, I.J.M. ; Dalod, M. ; Dudziak, D. ; Ziegler-Heitbrock, L.
Subsets of CD1c+DCs: Dendritic cell versus monocyte lineage.Luteijn, R.D. ; Praest, P. ; Thiele, F. ; Sadasivam, S.M. ; Singethan, K. ; Drijfhout, J.W. ; Bach, C.E. ; de Boer, S.M. ; Lebbink, R.J. ; Tao, S. ; Helfer, M. ; Bach, N.C. ; Protzer, U. ; Costa, A.I. ; Killian, J.A. ; Drexler, I. ; Wiertz, E.J.H.J.
A broad-spectrum antiviral peptide blocks infection of viruses by binding to phosphatidylserine in the viral envelope.Liu, P.J. ; Harris, J.M. ; Marchi, E. ; D’Arienzo, V. ; Michler, T. ; Wing, P.A.C. ; Magri, A. ; Ortega-Prieto, A.M. ; van de Klundert, M. ; Wettengel, J.M. ; Durantel, D. ; Dorner, M. ; Klenerman, P. ; Protzer, U. ; Giotis, E.S. ; McKeating, J.A.
Hypoxic gene expression in chronic hepatitis B virus infected patients is not observed in state-of-the-art in vitro and mouse infection models.Chakraborty, A. ; Ko, C. ; Henning, C. ; Lucko, A. ; Harris, J.M. ; Chen, F. ; Zhuang, X. ; Wettengel, J.M. ; Roessler, S. ; Protzer, U. ; McKeating, J.A.
Synchronised infection identifies early rate-limiting steps in the hepatitis B virus life cycle.Wettengel, J.M. ; Burwitz, B.J.
Innovative HBV animal models based on the entry receptor NTCP.Tian, X. ; Li, R. ; Jiang, Y. ; Zhao, F. ; Yu, Z. ; Wang, Y. ; Dong, Z. ; Liu, P. ; Li, X.
Bifidobacterium breve ATCC15700 pretreatment prevents alcoholic liver disease through modulating gut microbiota in mice exposed to chronic alcohol intake.Muenchhoff, M. ; Mairhofer, H. ; Nitschko, H. ; Grzimek-Koschewa, N. ; Hoffmann, D. ; Berger, A. ; Rabenau, H. ; Widera, M. ; Ackermann, N. ; Konrad, R. ; Zange, S. ; Graf, A. ; Krebs, S. ; Blum, H. ; Sing, A. ; Liebl, B. ; Wölfel, R. ; Ciesek, S. ; Drosten, C. ; Protzer, U. ; Boehm, S. ; Keppler, O.T.
Multicentre comparison of quantitative PCR-based assays to detect SARS-CoV-2, Germany, March 2020.Beyer, M. ; Abdullah, Z. ; Chemnitz, J.M. ; Maisel, D. ; Sander, J. ; Lehmann, C. ; Thabet, Y. ; Shinde, P.V. ; Schmidleithner, L. ; Köhne, M. ; Trebicka, J. ; Schierwagen, R. ; Hofmann, A. ; Popov, A. ; Lang, K.S. ; Oxenius, A. ; Buch, T. ; Kurts, C. ; Heikenwälder, M. ; Fätkenheuer, G. ; Lang, P.A. ; Hartmann, P. ; Knolle, P.A. ; Schultze, J.L.
Publisher Correction: Tumor-necrosis factor impairs CD4+ T cell–mediated immunological control in chronic viral infection (Nature Immunology, (2016), 17, 5, (593-603), 10.1038/ni.3399).Jung, S. ; Altstetter, S. ; Protzer, U.
Innate immune recognition and modulation in hepatitis D virus infection.Körber, N. ; Behrends, U. ; Protzer, U. ; Bauer, T.
Evaluation of T-activated proteins as recall antigens to monitor Epstein-Barr virus and human cytomegalovirus-specific T cells in a clinical trial setting.Hänze, J. ; Wegner, M. ; Nößner, E. ; Hofmann, R. ; Hegele, A.
Co-regulation of immune checkpoint PD-L1 with interferon-gamma signaling is associated with a survival benefit in renal cell cancer.Schreiber, S. ; Honz, M. ; Schiemann, M. ; Sette, A. ; Zielinski, C. ; Protzer, U. ; Wisskirchen, K.
Characterization of MHC class II-restricted t-cell receptors for t-cell therapy of HBV infection.Lucifora, J. ; Michelet, M. ; Rivoire, M. ; Protzer, U. ; Durantel, D. ; Zoulim, F.
Two-dimensional-cultures of primary human hepatocytes allow efficient HBV infection: Old tricks still work!Wolf, G.K. ; Glueck, T. ; Huebner, J. ; Muenchhoff, M. ; Hoffmann, D. ; French, L.E. ; Keppler, O.T. ; Protzer, U.
Clinical and epidemiological features of a family cluster of symptomatic and asymptomatic severe acute respiratory syndrome coronavirus 2 infection.Zhang, L. ; Hofer, T.P. ; Zawada, A.M. ; Rotter, B. ; Krezdorn, N. ; Nößner, E. ; Devaux, Y. ; Heine, G. ; Ziegler-Heitbrock, L.
Epigenetics in non-classical monocytes support their pro-inflammatory gene expression.Bararia, D. ; Hildebrand, J.A. ; Stolz, S. ; Haebe, S. ; Alig, S. ; Trevisani, C.P. ; Osorio-Barrios, F. ; Bartoschek, M.D. ; Mentz, M. ; Pastore, A. ; Gaitzsch, E. ; Heide, M. ; Jurinovic, V. ; Rautter, K. ; Gunawardana, J. ; Sabdia, M.B. ; Szczepanowski, M. ; Richter, J. ; Klapper, W. ; Louissaint, A. ; Ludwig, C. ; Bultmann, S. ; Leonhardt, H. ; Eustermann, S. ; Hopfner, K.P. ; Hiddemann, W. ; von Bergwelt-Baildon, M. ; Steidl, C. ; Kridel, R. ; Tobin, J.W.D. ; Gandhi, M.K. ; Weinstock, D.M. ; Schmidt-Supprian, M. ; Sárosi, M.B. ; Rudelius, M. ; Passerini, V. ; Mautner, J. ; Weigert, O.
Cathepsin S alterations induce a tumor-promoting immune microenvironment in follicular lymphoma.Huber, J.E. ; Ahlfeld, J. ; Scheck, M.K. ; Zaucha, M. ; Witter, K. ; Lehmann, L. ; Karimzadeh, H. ; Pritsch, M. ; Hoelscher, M. ; von Sonnenburg, F. ; Dick, A. ; Barba-Spaeth, G. ; Krug, A.B. ; Rothenfußer, S. ; Baumjohann, D.
Dynamic changes in circulating T follicular helper cell composition predict neutralising antibody responses after yellow fever vaccination.Namineni, S. ; O'Connor, T. ; Faure-Dupuy, S. ; Johansen, P. ; Riedl, T. ; Liu, K. ; Xu, H. ; Singh, I. ; Shinde, P. ; Li, F. ; Pandyra, A. ; Sharma, P. ; Ringelhan, M. ; Muschaweckh, A. ; Borst, K. ; Blank, P. ; Lampl, S. ; Neuhaus, K. ; Durantel, D. ; Farhat, R. ; Weber, A. ; Lenggenhager, D. ; Kündig, T.M. ; Staeheli, P. ; Protzer, U. ; Wohlleber, D. ; Holzmann, B. ; Binder, M. ; Breuhahn, K. ; Assmus, L.M. ; Nattermann, J. ; Abdullah, Z. ; Rolland, M. ; Dejardin, E. ; Lang, P.A. ; Lang, K.S. ; Karin, M. ; Lucifora, J. ; Kalinke, U. ; Knolle, P.A. ; Heikenwälder, M.
A dual role for hepatocyte-intrinsic canonical NF-κB signaling in virus control.Baumann, T. ; Dunkel, A. ; Schmid, C. ; Schmitt, S. ; Hiltensperger, M. ; Lohr, K. ; Laketa, V. ; Donakonda, S. ; Ahting, U. ; Lorenz-Depiereux, B. ; Heil, J.E. ; Schredelseker, J. ; Simeoni, L. ; Fecher, C. ; Körber, N. ; Bauer, T. ; Hüser, N. ; Hartmann, D. ; Laschinger, M. ; Eyerich, K. ; Eyerich, S. ; Anton, M. ; Streeter, M. ; Wang, T. ; Schraven, B. ; Spiegel, D. ; Assaad, F. ; Misgeld, T. ; Zischka, H. ; Murray, P.J. ; Heine, A. ; Heikenwälder, M. ; Korn, T. ; Dawid, C. ; Hofmann, T. ; Knolle, P.A. ; Höchst, B.
Regulatory myeloid cells paralyze T cells through cell-cell transfer of the metabolite methylglyoxal.Stubbe, M. ; Mai, J. ; Paulus, C. ; Stubbe, H.C. ; Berscheminski, J. ; Karimi, M. ; Hofmann, S. ; Weber, E. ; Hadian, K. ; Hay, R. ; Groitl, P. ; Nevels, M. ; Dobner, T. ; Schreiner, S.
Viral DNA binding protein SUMOylation promotes PML nuclear body localization next to viral replication centers.Grüllich, C. ; Nößner, E. ; Pfister, D. ; Grünwald, V.
Molekulare zielgerichtete Therapie und Immuntherapie des Prostatakarzinoms.Mirzaei, M.K. ; Khan, M.A.A. ; Ghosh, P. ; Taranu, Z.E. ; Taguer, M. ; Ru, J. ; Chowdhury, R. ; Kabir, M.M. ; Deng, L. ; Mondal, D. ; Maurice, C.F.
Bacteriophages isolated from stunted children can regulate gut bacterial communities in an age-specific manner.Chen, W. ; Zhang, K. ; Dong, P. ; Fanning, G. ; Tao, C. ; Zhang, H. ; Guo, S. ; Wang, Z. ; Hong, Y. ; Yang, X. ; Lai, S. ; Ding, H. ; Zhao, H. ; Zeng, C. ; Protzer, U. ; Zhang, D.
Noninvasive chimeric DNA profiling identifies tumor-originated HBV integrants contributing to viral antigen expression in liver cancer.Orth, M.F. ; Buecklein, V.L. ; Kampmann, E. ; Subklewe, M. ; Nößner, E. ; Cidre-Aranaz, F. ; Romero-Pérez, L. ; Wehweck, F.S. ; Lindner, L. ; Issels, R. ; Kirchner, T. ; Altendorf-Hofmann, A. ; Grunewald, T.G.P. ; Knoesel, T.
A comparative view on the expression patterns of PD-L1 and PD-1 in soft tissue sarcomas.Michler, T. ; Kosinska, A. ; Festag, J. ; Bunse, T. ; Su, J. ; Ringelhan, M. ; Imhof, H. ; Grimm, D. ; Steiger, K. ; Mogler, C. ; Heikenwalder, M. ; Michel, M.L. ; Guzman, C.A. ; Milstein, S. ; Sepp-Lorenzino, L. ; Knolle, P. ; Protzer, U.
Knockdown of virus antigen expression increases therapeutic vaccine efficacy in high-titer hepatitis B virus carrier mice.Herrmann, A. ; Roesner, M. ; Werner, T. ; Hauck, S.M. ; Koch, A. ; Bauer A. ; Schneider, M. ; Brack-Werner, R.
Potent inhibition of HIV replication in primary human cells by novel synthetic polyketides inspired by Aureothin.Müller, C. ; Kremb, S. ; Gonsior, M. ; Brack-Werner, R. ; Voolstra, C.R. ; Schmitt-Kopplin, P.
Advanced identification of global bioactivity hotspots via screening of the metabolic fingerprint of entire ecosystems.Hofmann, S. ; Mai, J. ; Masser, S. ; Groitl, P. ; Herrmann, A. ; Sternsdorf, T. ; Brack-Werner, R. ; Schreiner, S.
ATO (Arsenic Trioxide) effects on promyelocytic leukemia nuclear bodies reveals antiviral intervention capacity.Kurmayer, R. ; Entfellner, E. ; Weisse, T. ; Offterdinger, M. ; Rentmeister, A. ; Deng, L.
Chemically labeled toxins or bioactive peptides show a heterogeneous intracellular distribution and low spatial overlap with autofluorescence in bloom-forming cyanobacteria.Marschall, M. ; Strojan, H. ; Kiener, R. ; Wangen, C. ; Sonntag, E. ; Müller, R. ; Zeitträger, I. ; Wagner, S. ; Stamminger, T. ; Milbradt, J. ; Behrends, U. ; Körber, N. ; Bauer, T. ; Schrödel, S. ; Thirion, C. ; Wagner, R. ; Hutterer, C.
Differential upregulation of host cell protein kinases by the replication of α-, β- and γ-Herpesviruses provides a signature o virus-specific signalling.Issels, R.D. ; Lindner, L.H. ; von Bergwelt-Baildon, M. ; Lang, P. ; Rischpler, C. ; Diem, H. ; Mosetter, B. ; Eckl, J. ; Schendel, D.J. ; Salat, C. ; Stötzer, O. ; Burdach, S. ; von Lüttichau-Teichert, I. ; Handgretinger, R. ; Neumann, J. ; Kirchner, T. ; Steiger, K. ; Boxberg, M. ; Mansmann, U. ; Multhoff, G. ; Nößner, E.
Systemic antitumor effect by regional hyperthermia combined with low-dose chemotherapy and immunologic correlates in an adolescent patient with rhabdomyosarcoma - a case report.Tan, A.T. ; Schreiber, S.
Adoptive T-cell therapy for HBV-associated HCC and HBV infection.Jung, S. ; Altstetter, S. ; Wilsch, F. ; Shein, M. ; Schütz, A.K. ; Protzer, U.
Extracellular vesicles derived from Hepatitis-D Virus infected cells induce a proinflammatory cytokine response in human peripheral blood mononuclear cells and macrophages.Liu, X. ; Huang, H. ; Jiang, Y. ; Wang, T. ; Xu, Y. ; Abbaszade, G. ; Schnelle-Kreis, J. ; Zimmermann, R.
Assessment of German population exposure levels to PM10 based on multiple spatial-temporal data.Loffredo-Verde, E. ; Bhattacharjee, S. ; Malo, A. ; Festag, J. ; Kosinska, A. ; Ringelhan, M. ; Rim Sarkar, S. ; Steiger, K. ; Heikenwälder, M. ; Protzer, U. ; Prazeres da Costa, C.U.
Dynamic, helminth-induced immune modulation influences the outcome of acute and chronic hepatitis B virus infection.Qian, Z. ; Bruhn, T. ; D'Agostino, P.M. ; Herrmann, A. ; Haslbeck, M. ; Antal, N. ; Fiedler, H.P. ; Brack-Werner, R. ; Gulder, T.A.M.
Discovery of the streptoketides by direct cloning and rapid heterologous expression of a cryptic PKS II gene cluster from streptomyces sp. Tü 6314.Ma, T. ; Jiang, Y. ; Elbehery, A.H.A. ; Blank, S. ; Kurmayer, R. ; Deng, L.
Resilience of planktonic bacterial community structure in response to short-term weather deterioration during the growing season in an alpine lake.Afridi, S.Q. ; Kalali, B. ; Wettengel, J.M. ; Quitt, O. ; Semper, R. ; Gerhard, M. ; Protzer, U. ; Hoffmann, D.
Quantitation of norovirus-specific IgG before and after infection in immunocompromised patients.D'Arienzo, V. ; Magri, A. ; Harris, J.M. ; Wing, P.A.C. ; Ko, C. ; Rubio, C.O. ; Revill, P.A. ; Protzer, U. ; Balfe, P. ; McKeating, J.A.
A PCR assay to quantify patterns of HBV transcription.Schreiber, S. ; Honz, M. ; Schiemann, M. ; Sette, A. ; Zielinski, C. ; Protzer, U. ; Wisskirchen, K.
Characterization of MHC class II-restricted t-cell receptors for t-cell therapy of HBV infection.Gassen, N.C. ; Niemeyer, D. ; Corman, V.M. ; Martinelli, S. ; Gassen, A. ; Hafner, K. ; Papies, J. ; Mösbauer, K. ; Zellner, A. ; Zannas, A.S. ; Herrmann, A. ; Holsboer, F. ; Brack-Werner, R. ; Boshart, M. ; Müller-Myhsok, B. ; Drosten, C. ; Müller, M.A. ; Rein, T.
SKP2 attenuates autophagy through Beclin1-ubiquitination and its inhibition reduces MERS-Coronavirus infection.Sib, A. ; Milzarek, T.M. ; Herrmann, A. ; Oubraham, L. ; Müller, J.I. ; Pichlmair, A. ; Brack-Werner, R. ; Gulder, T.A.M.
Chemoenzymatic total synthesis of sorbicatechol structural analogues and evaluation of their antiviral potential.Ko, C. ; Bester, R. ; Zhou, X. ; Xu, Z. ; Blossey, C. ; Sacherl, J. ; Vondran, F.W.R. ; Gao, L. ; Protzer, U.
A new role for capsid assembly modulators to target mature hepatitis B virus capsids and prevent virus infection.Bianco, G. ; Montazeri, H. ; Quagliata, L. ; O'Connor, T. ; Ehmer, U. ; Oellinger, R. ; Matter, M. ; Gerhard, C.M. ; Ng, C.K.Y. ; Piscuoglio, S. ; Heikenwaelder, M. ; Terracciano, L.M.
HOXA13 drives hepatocytes proliferation and liver tumorigenesis in mice.Hu, J. ; Protzer, U. ; Siddiqui, A.
Revisiting hepatitis B virus: Challenges of curative therapies.O'Connor, T. ; Zhou, X. ; Kosla, J. ; Adili, A. ; Garcia Beccaria, M. ; Kotsiliti, E. ; Pfister, D. ; Johlke, A.-L. ; Sinha, A. ; Sankowski, R. ; Schick, M. ; Lewis, R. ; Dokalis, N. ; Seubert, B. ; Höchst, B. ; Inverso, D. ; Heide, D. ; Zhang, W. ; Weihrich, P. ; Manske, K. ; Wohlleber, D. ; Anton, M. ; Hoellein, A. ; Seleznik, G.M. ; Bremer, J. ; Bleul, S. ; Augustin, H.G. ; Scherer, F. ; Koedel, U. ; Weber, A. ; Protzer, U. ; Förster, R. ; Wirth, T. ; Aguzzi, A. ; Meissner, F. ; Prinz, M. ; Baumann, B. ; Höpken, U.E. ; Knolle, P.A. ; von Baumgarten, L. ; Keller, U. ; Heikenwälder, M.
Age-related gliosis promotes central nervous system lymphoma through CCL19-mediated tumor cell retention.Overacker, R. ; Banerjee, S. ; Neuhaus, G. ; Sephton, S. ; Herrmann, A. ; Strother, J. ; Brack-Werner, R. ; Blakemore, P. ; Loesgen, S.
Biological evaluation of molecules of the azaBINOL class as antiviral agents reveals specific inhibition of HIV-1 RNase H activity.Li, K. ; Neumann, K. ; Duhan, V. ; Namineni, S. ; Hansen, A.L. ; Wartewig, T. ; Kurgyis, Z. ; Holm, C.K. ; Heikenwälder, M. ; Lang, K.S. ; Ruland, J.
The uric acid crystal receptor Clec12A potentiates type I interferon responses.Hofer, T.P. ; van de Loosdrecht, A. ; Stahl-Hennig, C. ; Cassatella, M.A. ; Ziegler-Heitbrock, L.
6-sulfo LacNAc (Slan) as a marker for non-classical monocytes.Džunková, M. ; Low, S.J. ; Daly, J.N. ; Deng, L. ; Rinke, C. ; Hugenholtz, P.
Defining the human gut host-phage network through single-cell viral tagging.Kosinska, A. ; Moeed, A. ; Kallin, N. ; Festag, J. ; Su, J. ; Steiger, K. ; Michel, M.L. ; Protzer, U. ; Knolle, P.A.
Synergy of therapeutic heterologous prime-boost hepatitis B vaccination with CpG-application to improve immune control of persistent HBV infection.Koppe, C. ; Reisinger, F. ; Wehr, K. ; Vucur, M. ; Trautwein, C. ; Tacke, F. ; Heikenwalder, M. ; Luedde, T.
An NF-kappaB- and IKK-independent function of NEMO prevents hepatocarcinogenesis by suppressing compensatory liver regeneration.Möhl, B.S. ; Chen, J. ; Longnecker, R.
Gammaherpesvirus entry and fusion: A tale how two human pathogenic viruses enter their host cells.Overacker, R.D. ; Banerjee, S. ; Neuhaus, G.F. ; Milicevic Sephton, S. ; Herrmann, A. ; Strother, J.A. ; Brack-Werner, R. ; Blakemore, P.R. ; Loesgen, S.
Biological evaluation of molecules of the azaBINOL class as antiviral agents: Inhibition of HIV-1 RNase H activity by 7-isopropoxy-8-(naphth-1-yl) quinoline.Jiang, Y. ; Huang, H. ; Ma, T. ; Ru, J. ; Blank, S. ; Kurmayer, R. ; Deng, L.
Temperature response of planktonic microbiota in remote alpine lakes.Schreiber, S. ; Honz, M. ; Schiemann, M. ; Zielinski, C. ; Protzer, U. ; Wisskirchen, K.
Characterization of MHC class II-restricted t-cell receptors for t-cell therapy of HBV infection.Velkov, S. ; Protzer, U. ; Michler, T.
Approximation of the genotype distribution within global chronic hepatitis B virus infections.Schreiber, S. ; Honz, M. ; Schiemann, M. ; Zielinski, C. ; Protzer, U. ; Wisskirchen, K.
Characterization of a library of CD4+T cells for T-cell therapy of HBV infection.Su, J. ; Kosinska, A. ; Brunner, L. ; Sacherl, J. ; Frank, G. ; Singethan, K. ; Hasreiter, J. ; Thiele, F. ; Collin, N. ; Protzer, U.
Exploring TH1/TH2 adjuvants to improve the efficacy of the therapeutic vaccination against chronic hepatitis B.Oberhardt, V. ; Karimzadeh, H. ; Kiraithe, M.M. ; Alizei, E.S. ; Bockmann, J. ; Zur Wiesch, J.S. ; Budeus, B. ; Hoffmann, D. ; Wedemeyer, H. ; Rodriguez-Frias, F. ; Casillas, R. ; Buti, M. ; Smedile, A. ; Alavian, S.M. ; Heinold, A. ; Emmerich, F. ; Panning, M. ; Gostick, E. ; Price, D.A. ; Timm, J. ; Hofmann, M. ; Raziorrouh, B. ; Thimme, R. ; Protzer, U. ; Roggendorf, M. ; Neumann-Haefelin, C.
Viral escape contributes to the failure of hepatitis D virus-specific CD8+T-cells and drives evolution of HDV.Wisskirchen, K. ; Kah, J. ; Malo, A. ; Asen, T. ; Volz, T. ; Allweiss, L. ; Wettengel, J.M. ; Lütgehetmann, M. ; Urban, S. ; Bauer, T. ; Dandri, M. ; Protzer, U.
T cell receptor grafting allows virological control of hepatitis B virus infection.Tejera, B. ; López, R.E. ; Hidalgo, P. ; Cárdenas, R. ; Ballesteros, G. ; Rivillas, L. ; French, L. ; Amero, C. ; Pastor, N. ; Santiago, Á. ; Groitl, P. ; Dobner, T. ; Gonzalez, R.A.
The human adenovirus type 5 E1B 55kDa protein interacts with RNA promoting timely DNA replication and viral late mRNA metabolism.Abdelkareem, A.O. ; Khalil, M.I. ; Elaraby, M. ; Abbas, H. ; Elbehery, A.H.A.
VirNet: Deep attention model for viral reads identification.Malehmir, M. ; Pfister, D. ; Gallage, S. ; Szydlowska, M. ; Inverso, D. ; Kotsiliti, E. ; Leone, V. ; Peiseler, M. ; Surewaard, B.G.J. ; Rath, D. ; Ali, A. ; Wolf, M.J. ; Drescher, H. ; Healy, M.E. ; Dauch, D. ; Kroy, D. ; Krenkel, O. ; Kohlhepp, M. ; Engleitner, T. ; Olkus, A. ; Sijmonsma, T. ; Volz, J. ; Deppermann, C. ; Stegner, D. ; Helbling, P. ; Nombela-Arrieta, C. ; Rafiei, A. ; Hinterleitner, M. ; Rall, M. ; Baku, F. ; Borst, O. ; Wilson, C.L. ; Leslie, J. ; O'Connor, T. ; Weston, C.J. ; Adams, D.H. ; Sheriff, L. ; Teijeiro, A. ; Prinz, M. ; Bogeska, R. ; Anstee, N. ; Bongers, M.N. ; Notohamiprodjo, M. ; Geisler, T. ; Withers, D.J. ; Ware, J. ; Mann, D.A. ; Augustin, H.G. ; Vegiopoulos, A. ; Milsom, M.D. ; Rose, A.J. ; Lalor, P.F. ; Llovet, J.M. ; Pinyol, R. ; Tacke, F. ; Rad, R. ; Matter, M. ; Djouder, N. ; Kubes, P. ; Knolle, P.A. ; Unger, K. ; Zender, L. ; Nieswandt, B. ; Gawaz, M. ; Weber, A. ; Heikenwälder, M.
Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer.Wing, P.A. ; Davenne, T. ; Wettengel, J.M. ; Lai, A.G. ; Zhuang, X. ; Chakraborty, A. ; D'Arienzo, V. ; Kramer, C. ; Ko, C. ; Harris, J.M. ; Schreiner, S. ; Higgs, M. ; Roessler, S. ; Parish, J.L. ; Protzer, U. ; Balfe, P. ; Rehwinkel, J. ; McKeating, J.A.
A dual role for SAMHD1 in regulating HBV cccDNA and RT-dependent particle genesis.Bockmann, J.H. ; Stadler, D. ; Xia, Y. ; Ko, C. ; Wettengel, J.M. ; Zur Wiesch, J.S. ; Dandri, M. ; Protzer, U.
Comparative analysis of the antiviral effects mediated by type I and III interferons in hepatitis B virus infected hepatocytes.Kuczek, D.E. ; Larsen, A.M.H. ; Thorseth, M.L. ; Carretta, M. ; Kalvisa, A. ; Siersbæk, M.S. ; Simões, A.M.C. ; Roslind, A. ; Engelholm, L.H. ; Nößner, E. ; Donia, M. ; Svane, I.M. ; Straten, P.T. ; Grøntved, L. ; Madsen, D.H.
Collagen density regulates the activity of tumor-infiltrating T cells.Festag, M. ; Festag, J. ; Fräßle, S.P. ; Asen, T. ; Sacherl, J. ; Schreiber, S. ; Mück-Häusl, M. ; Busch, D.H. ; Wisskirchen, K. ; Protzer, U.
Evaluation of a fully human, hepatitis B virus-specific chimeric antigen receptor in an immunocompetent mouse model.Pabis, M. ; Corsini, L. ; Vincendeau, M. ; Tripsianes, K. ; Gibson, T.J. ; Brack-Werner, R. ; Sattler, M.
Modulation of HIV-1 gene expression by binding of a ULM motif in the Rev protein to UHM-containing splicing factors.Roblek, M. ; Protsyuk, D. ; Becker, P.F. ; Stefanescu, C. ; Gorzelanny, C. ; Garzon, J.F.G. ; Knopfova, L. ; Heikenwälder, M. ; Luckow, B. ; Schneider, S.W. ; Borsig, L.
CCL2 is a vascular permeability factor inducing CCR2-dependent endothelial retraction during lung metastasis.Karimzadeh, H. ; Kiraithe, M.M. ; Oberhardt, V. ; Alizei, E.S. ; Bockmann, J. ; Zur Wiesch, J.S. ; Budeus, B. ; Hoffmann, D. ; Wedemeyer, H. ; Cornberg, M. ; Krawczyk, A. ; Rashidi-Alavijeh, J. ; Rodríguez-Frías, F. ; Casillas, R. ; Buti, M. ; Smedile, A. ; Alavian, S.M. ; Heinold, A. ; Emmerich, F. ; Panning, M. ; Gostick, E. ; Price, D.A. ; Timm, J. ; Hofmann, M. ; Raziorrouh, B. ; Thimme, R. ; Protzer, U. ; Roggendorf, M. ; Neumann-Haefelin, C.
Mutations in hepatitis D virus allow it to escape detection by CD8+ T cells and evolve at the population level.Nehls, J. ; Businger, R. ; Hoffmann, M. ; Brinkmann, C. ; Fehrenbacher, B. ; Schaller, M. ; Maurer, B. ; Schönfeld, C. ; Kramer, D. ; Hailfinger, S. ; Pöhlmann, S. ; Schindler, M.
Release of immunomodulatory Ebola virus glycoprotein-containingmicrovesicles is suppressed by tetherin in a species-specific manner.Yuan, D. ; Luo, S. ; Xu, L. ; Zeng, X. ; Wu, Z.
Regulatory effect of host miR-101b-3p on parasitism of nematode Angiostrongylus cantonensis via superoxide dismutase 3.Bartenschlager, R. ; Urban, S. ; Protzer, U.
Towards curative therapy of chronic viral hepatitis.de Sousa-Pereira, P. ; Abrantes, J. ; Bauernfried, S. ; Pierini, V. ; Esteves, P.J. ; Keppler, O.T. ; Pizzato, M. ; Hornung, V. ; Fackler, O.T. ; Baldauf, H.-M.
The antiviral activity of rodent and lagomorph SERINC3 and SERINC5 is counteracted by known viral antagonists.Xia, Y. ; Schlapschy, M. ; Morath, V. ; Röder, N. ; Vogt, E.I. ; Stadler, D. ; Cheng, X. ; Dittmer, U. ; Sutter, K. ; Heikenwälder, M. ; Skerra, A. ; Protzer, U.
PASylated interferon α efficiently suppresses hepatitis B virus and induces anti-HBs seroconversion in HBV-transgenic mice.Rosdahl, A. ; Herzog, C. ; Frösner, G. ; Norén, T. ; Rombo, L. ; Askling, H.H.
An extra priming dose of hepatitis A vaccine to adult patients with rheumatoid arthritis and drug induced immunosuppression - A prospective, open-label, multi-center study (vol 21, pg 43, 2018).Jiang, Y. ; Khan, A. ; Huang, H. ; Tian, Y. ; Yu, X. ; Xu, Q. ; Mou, L. ; Lv, J. ; Zhang, P. ; Liu, P. ; Deng, L. ; Li, X.
Using nano-attapulgite clay compounded hydrophilic urethane foams (AT/HUFs) as biofilm support enhances oil-refinery wastewater treatment in a biofilm membrane bioreactor.van de Klundert, M. ; Ringelhan, M. ; Protzer, U.
Statins suppress hepatitis B virus replication and reduce hepatoma cell viability by interfering with Rho-GTPases.Zhang, D. ; Chen, W. ; Zhang, K. ; Dong, P. ; Protzer, U. ; Zeng, C.
Viral integration profiles in the plasma cell-free DNA from patients with HBV infection well represent tumor clone compositions during HCC development.Wisskirchen, K. ; Kah, J. ; Malo, A. ; Allweiss, L. ; Metzger, K. ; Volz, T. ; Krackhardt, A. ; Dandri-Petersen, M. ; Protzer, U.
T cells grafted with HBV-specific T-cell receptors of high functional avidity achieve functional cure of HBV infection in humanized mice.Michler, T. ; Kosinska, A. ; Bunse, T. ; Heikenwaelder, M. ; Grimm, D. ; Milstein, S. ; Sepp-Lorenzino, L. ; Protzer, U.
Combinatorial RNAi/vaccination therapy for chronic hepatitis B achieves long-term functional cure in preclinical mouse model.Hoffmann, M. ; Nehlmeier, I. ; Brinkmann, C. ; Krähling, V. ; Behner, L. ; Moldenhauer, A.S. ; Krüger, N. ; Nehls, J. ; Schindler, M. ; Hoenen, T. ; Maisner, A. ; Becker, S. ; Pöhlmann, S.
Tetherin inhibits nipah Vvrus but not ebola virus replication in fruit bat cells.Preissler, G. ; Nößner, E. ; Warnecke, G. ; Knoefel, A. ; Schramm, R. ; Hatz, R. ; Haverich, A. ; Strobl, N.
Systemic treg levels are associated with functional treg differences and correlate with the immunological risk in lung transplant recipients.Festag, M. ; Wisskirchen, K. ; Hasreiter, J. ; Schreiber, S. ; Abken, H. ; Protzer, U.
Evaluation of a fully human car for the treatment of hepatitis B virus infection in an immunocompetent mouse model.Gehring, A. ; Protzer, U.
Targeting innate and adaptive immune responses to cure chronic HBV infection.Velkov, S. ; Ott, J.J. ; Protzer, U. ; Michler, T.
The global hepatitis B virus genotype distribution approximated from available genotyping data.Manske, K. ; Kallin, N. ; König, V. ; Schneider, A. ; Kurz, S. ; Bosch, M. ; Welz, M. ; Cheng, R.L. ; Bengsch, B. ; Steiger, K. ; Protzer, U. ; Thimme, R. ; Knolle, P.A. ; Wohlleber, D.
Outcome of antiviral immunity in the liver is shaped by the level of antigen expressed in infected hepatocytes.Burwitz, B.J. ; Wettengel, J.M. ; Mück-Häusl, M. ; Hammond, K.B. ; Ringelhan, M. ; Ko, C. ; Reed, J. ; Norris, R. ; Park, B. ; Moller-Tank, S. ; Esser, K. ; Greenel, J. ; Wu, H. ; Abdulhaqq, S. ; Webb, G. ; Sutton, W.F. ; Klug, A. ; Swanson, T. ; Legasse, A.W. ; Asokan, A. ; Haigwood, N.L. ; Protzer, U. ; Sacha, J.B.
A new HIV/HBV co-infection model: Hepatocytic expression of human sodium taurocholate cotransporting polypeptide (NTCP) Enables Hepatitis B Virus Infection of Macaques.Michler, T. ; Kosinska, A. ; Grimm, D. ; Heikenwalder, M. ; Milstein, S. ; Sepp-Lorenzino, L. ; Knolle, P.A. ; Protzer, U.
Suppression of hepatitis B virus antigens by RNA interference enables therapeutic vaccination to achieve immune control in high-titer virus carriers.Kosinska, A. ; Kallin, A. ; Protzer, U. ; Knolle, P.A.
Overcoming liver tolerance to clear persistent HBV infection.von Olshausen, G. ; Quasdorff, M. ; Bester, R. ; Arzberger, S. ; Ko, C. ; van de Klundert, M. ; Zhang, K. ; Odenthal, M. ; Ringelhan, M. ; Niessen, C.M. ; Protzer, U.
Hepatitis B virus promotes β-catenin-signalling and disassembly of adherens junctions in a Src kinase dependent fashion.Ko, C. ; Chakraborty, A. ; Chou, W.M. ; Hasreiter, J. ; Wettengel, J.M. ; Stadler, D. ; Bester, R. ; Asen, T. ; Zhang, K. ; Wisskirchen, K. ; McKeating, J.A. ; Ryu, W.S. ; Protzer, U.
Hepatitis B virus genome recycling and de novo secondary infection events maintain stable cccDNA levels.Martin-Medina, A. ; Lehmann, M. ; Burgy, O. ; Hermann, S. ; Baarsma, H.A. ; Wagner, D.E. ; De Santis, M. ; Ciolek, F. ; Hofer, T.P. ; Frankenberger, M. ; Aichler, M. ; Lindner, M. ; Gesierich, W. ; Guenther, A. ; Walch, A.K. ; Coughlan, C. ; Wolters, P. ; Lee, J.S. ; Behr, J. ; Königshoff, M.
Increased extracellular vesicles mediate WNT5A signaling in idiopathic pulmonary fibrosis.Schiwon, M. ; Ehrke-Schulz, E. ; Oswald, A. ; Bergmann, T. ; Michler, T. ; Protzer, U. ; Ehrhardt, A.
One-vector system for multiplexed CRISPR/Cas9 against hepatitis B virus cccDNA utilizing high-capacity adenoviral vectors.Faure-Dupuy, S. ; Vegna, S. ; Aillot, L. ; Dimier, L. ; Esser, K. ; Broxtermann, M. ; Bonnin, M. ; Bendriss-Vermare, N. ; Rivoire, M. ; Passot, G. ; Lesurtel, M. ; Mabrut, J.Y. ; Ducerf, C. ; Salvetti, A. ; Protzer, U. ; Zoulim, F. ; Durantel, D. ; Lucifora, J.
Characterization of pattern recognition receptor expression and functionality in liver primary cells and derived cell lines.Stadler, D. ; Hess, J. ; Schneider, J. ; Lasitschka, F. ; Ringelhan, M. ; Ko, C. ; Chou, W.M. ; Wettengel, J.M. ; Unger, K. ; Protzer, U.
Identification of ISG20 as the nuclease involved in Interferon-induced decline of HBV cccDNA.Schreiber, S. ; Honz, M. ; Schiemann, M. ; Protzer, U. ; Wisskirchen, K.
Generating CD4+T cells for the T-cell therapy of HBV infection.Chou, W.M. ; Mück-Häusl, M. ; Ko, C. ; Wettengel, J.M. ; Protzer, U. ; Stadler, D.
Establishment and characterization of a novel recombinant reporter HBV utilizing the Cre-lox recombination system.Feuerherd, M. ; Körber, N. ; Boesecke, C. ; Mohrmann, K. ; Froeschl, G. ; Ringelhan, M. ; Geisler, F. ; Rockstroh, J. ; Protzer, U. ; Bauer, T.
Altered HBV-specific CD4+T-cell Responses in HBV/HIV-1 Co-versus HBV Mono-infected Patients.Brenke, J.K. ; Popowicz, G.M. ; Schorpp, K.K. ; Rothenaigner, I. ; Roesner, M. ; Meininger, I. ; Kalinski, C. ; Ringelstetter, L. ; R'kyek, O. ; Jürjens, G. ; Vincendeau, M. ; Plettenburg, O. ; Sattler, M. ; Krappmann, D. ; Hadian, K.
Targeting TRAF6 E3 ligase activity with a small-molecule inhibitor combats autoimmunity.Karimzadeh, H. ; Kiraithe, M.M. ; Kosinska, A. ; Glaser, M. ; Fiedler, M. ; Oberhardt, V. ; Alizei, E.S. ; Hofmann, M. ; Mok, J.Y. ; Nguyen, M. ; van Esch, W.J.E. ; Budeus, B. ; Grabowski, J. ; Homs, M. ; Olivero, A. ; Keyvani, H. ; Rodríguez-Frías, F. ; Tabernero, D. ; Buti, M. ; Heinold, A. ; Alavian, S.M. ; Bauer, T. ; Wiesch, J.S.z. ; Raziorrouh, B. ; Hoffmann, D. ; Smedile, A. ; Rizzetto, M. ; Wedemeyer, H. ; Timm, J. ; Antes, I. ; Neumann-Haefelin, C. ; Protzer, U. ; Roggendorf, M.
Amino acid substitutions within HLA-B*27-restricted T cell epitopes prevent recognition by hepatitis delta virus-specific CD8+ T cells.González-Hernández, M. ; Hoffmann, M. ; Brinkmann, C. ; Nehls, J. ; Winkler, M. ; Schindler, M. ; Pöhlmann, S.
A GXXXA motif in the transmembrane domain of the Ebola virus glycoprotein is required for tetherin antagonism.Kunze, C. ; Herrmann, A. ; Bauer, A. ; Brack-Werner, R.
Are there strategies against latent infection?Simon, L. ; Karg, S. ; Westermann, A.J. ; Engel, M. ; Elbehery, A.H.A. ; Hense, B.A. ; Heinig, M. ; Deng, L. ; Theis, F.J.
MetaMap: An atlas of metatranscriptomic reads in human disease-related RNA-seq data.Chen, Y. ; Jiang, Y. ; Huang, H. ; Mou, L. ; Ru, J. ; Zhao, J. ; Xiao, S.
Long-term and high-concentration heavy-metal contamination strongly influences the microbiome and functional genes in Yellow River sediments.Ning, X. ; Luckenbaugh, L. ; Liu, K. ; Bruss, V. ; Sureau, C. ; Hu, J.J.
Common and distinct capsid and surface protein requirements for secretion of complete and genome-free hepatitis B virions.Reichel, A. ; Stilp, A.C. ; Scherer, M. ; Reuter, N. ; Lukassen, S. ; Kasmapour, B. ; Schreiner, S. ; Cicin-Sain, L. ; Winterpacht, A. ; Stamminger, T.
Chromatin-remodeling factor SPOC1 acts as a cellular restriction factor against human cytomegalovirus by repressing the major immediate early promoter.Ibrahim, B. ; McMahon, D.P. ; Hufsky, F. ; Beer, M. ; Deng, L. ; Mercier, P.L. ; Palmarini, M. ; Thiel, V. ; März, M.
A new era of virus bioinformatics.Dembek, C.J. ; Protzer, U. ; Roggendorf, M.
Overcoming immune tolerance in chronic hepatitis B by therapeutic vaccination.Müncheberg, S. ; Hay, R.T. ; Ip, W.H. ; Meyer, T. ; Weiß, C. ; Brenke, J.K. ; Masser, S. ; Hadian, K. ; Dobner, T. ; Schreiner, S.
E1B-55K mediated regulation of RNF4 STUbL promotes HAdV gene expression.Jubb, A. ; Hofer, T.P. ; Hume, D.A. ; Ziegler-Heitbrock, L.
The preterm labor associated ADAMTS2 gene is induced by glucocorticoids.Elbehery, A.H.A. ; Feichtmayer, J. ; Singh, D. ; Griebler, C. ; Deng, L.
The human virome protein cluster database (HVPC): A human viral metagenomic database for diversity and function annotation.Weinberger, B. ; Haks, M.C. ; de Paus, R.A. ; Ottenhoff, T.H.M. ; Bauer, T. ; Grubeck-Loebenstein, B.
Impaired immune response to primary but not to booster vaccination against hepatitis B in older adults.Issels, R. ; Lindner, L. ; Buecklein, V. ; Multhoff, G. ; Salat, C. ; von Bergwelt, M. ; Nößner, E.
Regional hyperthermia and immuno-oncology.Blume, K. ; Körber, N. ; Hoffmann, D. ; Wolfarth, B.
Training load, immune status, and clinical outcomes in young athletes: A controlled, prospective, longitudinal study.Ringelhan, M. ; Pfister, D. ; O'Connor, T. ; Pikarsky, E. ; Heikenwalder, M.
The immunology of hepatocellular carcinoma.Suffner, S. ; Gerstenberg, N. ; Patra, M. ; Ruibal, P. ; Orabi, A. ; Schindler, M. ; Bruss, V.
Domains of the hepatitis B virus small surface protein S mediating oligomerization.Hufsky, F. ; Ibrahim, B. ; Beer, M. ; Deng, L. ; Mercier, P.L. ; McMahon, D.P. ; Palmarini, M. ; Thiel, V. ; März, M.
Virologists-Heroes need weapons.Lorentzen, A.R. ; Becker, P.F. ; Kosla, J. ; Saini, M. ; Weidele, K. ; Ronchi, P. ; Klein, C. ; Wolf, M.J. ; Geist, F. ; Seubert, B. ; Ringelhan, M. ; Mihic-Probst, D. ; Esser, K. ; Roblek, M. ; Kuehne, F. ; Bianco, G. ; O'Connor, T. ; Müller, Q. ; Schuck, K. ; Lange, S. ; Hartmann, D. ; Spaich, S. ; Groß, O. ; Utikal, J. ; Haferkamp, S. ; Sprick, M.R. ; Damle-Vartak, A. ; Hapfelmeier, A. ; Hüser, N. ; Protzer, U. ; Trumpp, A. ; Saur, D. ; Vartak, N. ; Klein, C.A. ; Polzer, B. ; Borsig, L. ; Heikenwälder, M.
Single cell polarity in liquid phase facilitates tumour metastasis.Schirmer, D. ; Storz, I. ; Wisskirchen, K. ; Feederle, R. ; Schmidt, O. ; Abken, H. ; Protzer, U. ; Burdach, S. ; Richter, G.
GPR64-specific CAR-trnasgenic T cells selectively kill Ewing sarcoma cells.Cirac, A. ; Stützle, S. ; Dieckmeyer, M. ; Adhikary, D. ; Moosmann, A. ; Körber, N. ; Bauer, T. ; Witter, K. ; Delecluse, H.J. ; Behrends, U. ; Mautner, J.
Epstein-Barr virus strain heterogeneity impairs human T-cell immunity.Schwarzenböck, C. ; Schaffer, A. ; Nößner, E. ; Nelson, P.J. ; Huss, R. ; Rieger, B.
Fluorescent polyvinylphosphonate bioconjugates for selective cellular delivery.Esser, K. ; Lucifora, J. ; Wettengel, J.M. ; Singethan, K. ; Glinzer, A. ; Zernecke, A. ; Protzer, U.
Lipase inhibitor orlistat prevents hepatitis B virus infection by targeting an early step in the virus life cycle.Freudenberger, N. ; Meyer, T. ; Groitl, P. ; Dobner, T. ; Schreiner, S.
HAdV protein V core protein is targeted by the host SUMOylation machinery to limit essential viral functions.Kunze, C. ; Börner, K. ; Kienle, E. ; Orschmann, T. ; Rusha, E. ; Schneider, M. ; Radivojkov-Blagojevic, M. ; Drukker, M. ; Desbordes, S.C. ; Grimm, D. ; Brack-Werner, R.
Synthetic AAV/CRISPR vectors for blocking HIV-1 expression in persistently infected astrocytes.Reiter, K. ; Polzer, H. ; Krupka, C. ; Maiser, A. ; Vick, B. ; Rothenberg-Thurley, M. ; Metzeler, K.H. ; Dörfel, D. ; Salih, H.R. ; Jung, G. ; Nößner, E. ; Jeremias, I. ; Hiddemann, W. ; Leonhardt, H. ; Spiekermann, K. ; Subklewe, M. ; Greif, P.A.
Tyrosine kinase inhibition increases the cell surface localization of FLT3-ITD and enhances FLT3-directed immunotherapy of acute myeloid leukemia.Kallin, N. ; Bosch, M. ; Manske, K. ; Protzer, U. ; Wohlleber, D. ; Knolle, P.A.
Exhaustion of virus-specific CXCR6+liver-resident memory CD8 T cells during persistent liver infection.Wisskirchen, K. ; Kah, J. ; Malo, A. ; Allweiss, L. ; Volz, T. ; Dandri, M. ; Protzer, U.
Hepatitis B virus (HBV)-specific T cell receptors with high functional avidity redirect T cells to eliminate HBV.Jung, S. ; Bauer, S.
RIG I senses ribosomal RNA derived degradation products.Storz, I. ; Schirmer, D. ; Wisskirchen, K. ; Feederle, R. ; Schmidt, O. ; Abken, H. ; Protzer, U. ; Burdach, S. ; Richter, G.H.S.
Therapeutic potential of GPR64 specific CAR T cells in pediatric sarcomas.Baldauf, H.M. ; Stegmann, L. ; Schwarz, S.M. ; Ambiel, I. ; Trotard, M. ; Martin, M. ; Burggraf, M. ; Lenzi, G.M. ; Lejk, H. ; Pan, X. ; Fregoso, O.I. ; Lim, E.S. ; Abraham, L. ; Nguyen, L.A. ; Rutsch, F. ; König, R. ; Kim, B. ; Emerman, M. ; Fackler, O.T.
Vpx overcomes a SAMHD1-independent block to HIV reverse transcription that is specific to resting CD4 T cells.Seleznik, G.M. ; Reding, T. ; Peter, L. ; Gupta, A. ; Steiner, S.G. ; Sonda, S. ; Verbeke, C.S. ; Dejardin, E. ; Khatkov, I. ; Segerer, S. ; Heikenwälder, M. ; Graf, R.
Development of autoimmune pancreatitis is independent of CDKN1A/p21-mediated pancreatic inflammation.Wolf, Y. ; Shemer, A. ; Polonsky, M. ; Gross, M. ; Mildner, A. ; Yona, S. ; David, E. ; Kim, K.W. ; Goldmann, T. ; Amit, I. ; Heikenwälder, M. ; Nedospasov, S.A. ; Prinz, M. ; Friedman, N. ; Jung, S.
Autonomous TNF is critical for in vivo monocyte survival in steady state and inflammation.Xia, Y. ; Stadler, D. ; Ko, C. ; Protzer, U.
Analyses of HBV cccDNA quantification and modification.Rosdahl, A. ; Herzog, C. ; Frösner, G. ; Norén, T. ; Rombo, L. ; Askling, H.H.
An extra priming dose of hepatitis A vaccine to adult patients with rheumatoid arthritis and drug induced immunosuppression - A prospective, open-label, multi-center study.Werner, J.M. ; Adenugba, A. ; Protzer, U.
Immune reconstitution after HCV clearance with direct antiviral agents: Potential consequences for patients with HCC?Essig, K. ; Hu, D. ; Guimaraes, J.C. ; Alterauge, D. ; Edelmann, S.L. ; Raj, T. ; Kranich, J. ; Behrens, G. ; Heiseke, A.F. ; Floess, S. ; Klein, J. ; Maiser, A. ; Marschall, S. ; Hrabě de Angelis, M. ; Leonhardt, H. ; Calkhoven, C.F. ; Nößner, E. ; Brocker, T. ; Huehn, J. ; Krug, A.B. ; Zavolan, M. ; Baumjohann, D. ; Heissmeyer, V.
Roquin suppresses the PI3K-mTOR signaling pathway to inhibit T helper cell differentiation and conversion of treg to Tfr cells.Burwitz, B.J. ; Wettengel, J.M. ; Mück-Häusl, M. ; Ringelhan, M. ; Ko, C. ; Festag, M.M. ; Hammond, K.B. ; Northrup, M. ; Bimber, B.N. ; Jacob, T. ; Reed, J.S. ; Norris, R. ; Park, B. ; Moller-Tank, S. ; Esser, K. ; Greene, J.M. ; Wu, H.L. ; Abdulhaqq, S. ; Webb, G. ; Sutton, W.F. ; Klug, A. ; Swanson, T. ; Legasse, A.W. ; Vu, T.Q. ; Asokan, A. ; Haigwood, N.L. ; Protzer, U. ; Sacha, J.B.
Hepatocytic expression of human sodium-taurocholate cotransporting polypeptide enables hepatitis B virus infection of macaques.Feichtmayer, J. ; Deng, L. ; Griebler, C.
Antagonistic microbial interactions: Contributions and potential applications for controlling pathogens in the aquatic systems.Inturi, R. ; Mun, K. ; Singethan, K. ; Schreiner, S. ; Punga, T.
Human adenovirus infection causes cellular E3 ubiquitin ligase MKRN1 degradation involving the viral core protein pVII.Egaña, I. ; Kaito, H. ; Nitzsche, A. ; Becker, L. ; Ballester-Lopez, C. ; Niaudet, C. ; Petkova, M. ; Liu, W. ; Vandlandewijck, M. ; Vernaleken, A. ; Klopstock, T. ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Rask-Andersen, H. ; Johansson, H.J. ; Lehtiö, J. ; He, L. ; Yildirim, A.Ö. ; Hellström, M. ; German Mouse Clinic Consortium (Aguilar-Pimentel, J.A. ; Ollert, M. ; Schmidt-Weber, C.B. ; Amarie, O.V. ; Graw, J. ; Beckers, J. ; Garrett, L. ; Hölter, S.M. ; Zimprich, A. ; Wurst, W. ; Moreth, K. ; Bekeredjian, R. ; Neff, F. ; Calzada-Wack, J. ; Rácz, I. ; Zimmer, A. ; Rathkolb, B. ; Wolf, E. ; Rozman, J. ; Klingenspor, M. ; Stöger, T. ; Eickelberg, O. ; Treise, I. ; Busch, D.H. ; Östereicher, M.A. ; Steinkamp, R. ; Lengger, C. ; Maier, H. ; Stoeger, C. ; Leuchtenberger, S.)
Female mice lacking Pald1 exhibit endothelial cell apoptosis and emphysema.Strobl, N. ; Winter, H. ; Warnecke, G. ; Nößner, E. ; Knofel, A. ; Schramm, R. ; Hatz, R. ; Haverich, A. ; Preissler, G.
Systemic treg levels early after lung transplantation are associated with the risk for acute rejection episodes.Li, Y. ; Xia, Y. ; Han, M. ; Chen, G. ; Zhang, D. ; Thasler, W.E. ; Protzer, U. ; Ning, Q.
IFN-α-mediated base excision repair pathway correlates with antiviral response against hepatitis B virus infection.Neuenhahn, M. ; Albrecht, J. ; Odendahl, M. ; Schlott, F. ; Doessinger, G. ; Schiemann, M. ; Lakshmipathi, S. ; Martin, K. ; Bunjes, D. ; Harsdorf, S. ; Weissinger, E.M. ; Menzel, H. ; Verbeek, M. ; Uharek, L. ; Kroeger, N. ; Wagner, E. ; Kobbe, G. ; Schroeder, T. ; Schmitt, M. ; Held, G. ; Herr, W. ; Germeroth, L. ; Bönig, H. ; Tonn, T. ; Einsele, H. ; Busch, D.H. ; Grigoleit, G.U.
Transfer of minimally manipulated CMV-specific T cells from stem cell or third-party donors to treat CMV infection after allo-HSCT.Hofmann, S. ; Dehn, S. ; Businger, R. ; Bolduan, S. ; Schneider, M. ; Debyser, Z. ; Brack-Werner, R. ; Schindler, M.
Dual role of the chromatin-binding factor PHF13 in the pre- and post-integration phases of HIV-1 replication.Bolduan, S. ; Koppensteiner, H. ; Businger, R. ; Rebensburg, S. ; Kunze, C. ; Brack-Werner, R. ; Draenert, R. ; Schindler, M.
T cells with low CD2 levels express reduced restriction factors and are preferentially infected in therapy naïve chronic HIV-1 patients.Ringelhan, M. ; McKeating, J.A. ; Protzer, U.
Viral hepatitis and liver cancer.Boege, Y. ; Malehmir, M. ; Healy, M.E. ; Bettermann, K. ; Lorentzen, A.R. ; Vucur, M. ; Ahuja, A.K. ; Böhm, F. ; Mertens, J.C. ; Shimizu, Y. ; Frick, L. ; Remouchamps, C. ; Mutreja, K. ; Kähne, T. ; Sundaravinayagam, D. ; Wolf, M.J. ; Rehrauer, H. ; Koppe, C. ; Speicher, T. ; Padrissa-Altés, S. ; Maire, R. ; Schattenberg, J.M. ; Jeong, J.S. ; Liu, L. ; Zwirner, S. ; Boger, R.H. ; Hüser, N. ; Davis, R.J. ; Müllhaupt, B. ; Moch, H. ; Schulze-Bergkamen, H. ; Clavien, P.A. ; Werner, S. ; Borsig, L. ; Luther, S.A. ; Jost, P.J. ; Weinlich, R. ; Unger, K. ; Behrens, A. ; Hillert, L. ; Dillon, C. ; Di Virgilio, M. ; Wallach, D. ; Dejardin, E. ; Zender, L. ; Naumann, M. ; Walczak, H. ; Green, D.R. ; Lopes, M. ; Lavrik, I.N. ; Luedde, T. ; Heikenwälder, M. ; Weber, A.
A dual role of caspase-8 in triggering and sensing proliferation-associated DNA damage, a key determinant of liver cancer development.Wisskirchen, K. ; Metzger, K. ; Schreiber, S. ; Asen, T. ; Weigand, L. ; Dargel, C. ; Witter, K. ; Kieback, E. ; Sprinzl, M.F. ; Uckert, W. ; Schiemann, M. ; Busch, D.H. ; Krackhardt, A.M. ; Protzer, U.
Isolation and functional characterization of hepatitis B virus-specific T-cell receptors as new tools for experimental and clinical use.Shevtsov, M. ; Zhao, L. ; Protzer, U. ; Klundert, M.A.A.
Applicability of metal nanoparticles in the detection and monitoring of hepatitis B virus infection.Bergmann, H. ; Roth, S. ; Pechloff, K. ; Kiss, E.A. ; Kühn, S. ; Heikenwälder, M. ; Diefenbach, A. ; Greten, F.R. ; Ruland, J.
Card9-dependent IL-1β regulates IL-22 production from group 3 innate lymphoid cells and promotes colitis-associated cancer.Sautto, G.A. ; Diotti, R.A. ; Wisskirchen, K. ; Kahle, K.M.
New insights for immune-based diagnosis and therapy for infectious diseases.Hösel, M. ; Quasdorff, M. ; Ringelhan, M. ; Kashkar, H. ; Debey-Pascher, S. ; Sprinzl, M.F. ; Bockmann, J.H. ; Arzberger, S. ; Webb, D. ; von Olshausen, G. ; Weber, A. ; Schultze, J.L. ; Büning, H. ; Heikenwälder, M. ; Protzer, U.
Hepatitis B virus activates signal transducer and activator of transcription 3 supporting hepatocyte survival and virus replication.Golsaz-Shirazi, F. ; Amiri, M.M. ; Farid, S. ; Bahadori, M. ; Bohne, F. ; Altstetter, S. ; Wolff, L. ; Kazemi, T. ; Khoshnoodi, J. ; Hojjat-Farsangi, M. ; Chudy, M. ; Jeddi-Tehrani, M. ; Protzer, U. ; Shokri, F.
Construction of a hepatitis B virus neutralizing chimeric monoclonal antibody recognizing escape mutants of the viral surface antigen (HBsAg).Kaminski, M. ; Grummel, V. ; Hoffmann, D. ; Berthele, A. ; Hemmer, B.
The spectrum of aseptic central nervous system infections in southern Germany - demographic, clinical and laboratory findings.Schreiner, S. ; Nassal, M.
A role for the host DNA damage response in Hepatitis B Virus cccDNA formation-and beyond?Schlenker, R. ; Olguín-Contreras, L.F. ; Leisegang, M. ; Schnappinger, J. ; Disovic, A. ; Rühland, S. ; Nelson, P.J. ; Leonhardt, H. ; Harz, H. ; Wilde, S. ; Schendel, D.J. ; Uckert, W. ; Willimsky, G. ; Nößner, E.
Chimeric PD-1:28 receptor upgrades low-avidity T cells and restores effector function of tumor-infiltrating lymphocytes for adoptive cell therapy.Ko, C. ; Michler, T. ; Protzer, U.
Novel viral and host targets to cure hepatitis B.Bartel, S. ; Schulz, N. ; Alessandrini, F. ; Schamberger, A.C. ; Pagel, P. ; Theis, F.J. ; Milger, K. ; Nößner, E. ; Stick, S.M. ; Kicic, A. ; Eickelberg, O. ; Freishtat, R.J. ; Krauss-Etschmann, S.
Pulmonary microRNA profiles identify involvement of Creb1 and Sec14l3 in bronchial epithelial changes in allergic asthma.Hanin, G. ; Yayon, N. ; Tzur, Y. ; Haviv, R. ; Bennett, E.R. ; Udi, S. ; Krishnamoorthy, Y.R. ; Kotsiliti, E. ; Zangen, R. ; Efron, B. ; Tam, J. ; Pappo, O. ; Shteyer, E. ; Pikarsky, E. ; Heikenwälder, M. ; Greenberg, D.S. ; Soreq, H.
miRNA-132 induces hepatic steatosis and hyperlipidaemia by synergistic multitarget suppression.Yuan, D.T. ; Ringelhan, M. ; Connor, T.O. ; Simonavicius, N. ; Reisinger, F. ; Leone, V. ; Protzer, U. ; Unger, K. ; Heikenwälder, M.
Kupffer cell-derived Tnf triggers cholangiocellular tumorigenesis through JNK due to chronic mitochondrial dysfunction and ROS.Protzer, U.
Viral hepatitis: The bumpy road to animal models for HBV infection.Michler, T. ; Kosinska, A. ; Bunse, T. ; Heikenwälder, M. ; Grimm, D. ; Milstein, S. ; Sepp-Lorenzino, L. ; Protzer, U.
Preclinical study of a combinatorial RNAi/vaccination therapy as a potential cure for chronic hepatitis B.Wisskirchen, K. ; Kah, J. ; Metzger, K. ; Weigand, L. ; Uckert, W. ; Schiemann, M. ; Volz, T. ; Krackhardt, A. ; Dandri, M. ; Protzer, U.
Hepatitis B virus-specific T cell receptors with high functional avidity redirect T cells to eliminate HBV.Sissoko, D. ; Keita, M. ; Diallo, B. ; Aliabadi, N. ; Fitter, D.L. ; Dahl, B.A. ; Bore, J.A. ; Koundouno, F.R. ; Singethan, K. ; Meisel, S. ; Enkirch, T. ; Mazzarelli, A. ; Amburgey, V. ; Faye, O. ; Sall, A.A. ; Magassouba, N. ; Carroll, M.W. ; Anglaret, X. ; Malvy, D. ; Formenty, P. ; Aylward, R.B. ; Keita, S. ; Djingarey, M.H. ; Loman, N.J. ; Guenther, S. ; Duraffour, S.
Ebola virus persistence in breast milk after no reported illness: A likely source of virus transmission from mother to child.Appelman, M.D. ; Chakraborty, A. ; Protzer, U. ; McKeating, J.A. ; van de Graaf, S.F.J.
N-glycosylation of the Na+-taurocholate cotransporting polypeptide (NTCP) determines its trafficking and stability and is required for hepatitis B Vvrus infection.Schlott, F. ; Steubl, D. ; Hoffmann, D. ; Matevossian, E. ; Lutz, J. ; Heemann, U. ; Hösel, V. ; Busch, D.H. ; Renders, L. ; Neuenhahn, M.
Primary cytomegalovirus infection in seronegative kidney transplant patients is associated with protracted cold ischemic time of seropositive donor organs.Xia, Y. ; Cheng, X. ; Blossey, C.K. ; Wisskirchen, K. ; Esser, K. ; Protzer, U.
Secreted interferon-inducible factors restrict hepatitis B and C virus entry in vitro.Yuan, D.T. ; Heikenwälder, M.
Kupffer cell-derived TNF triggers cholangiocellular tumorigenesis through JNK due to chronic mitochondrial dysfunction and ROS.Xia, Y. ; Protzer, U.
Control of hepatitis B virus by cytokines.Smida, J. ; Xu, H. ; Zhang, Y. ; Baumhoer, D. ; Ribi, S. ; Kovac, M. ; von Luettichau, I. ; Bielack, S. ; O'Leary, V.B. ; Leib-Mösch, C. ; Frishman, D. ; Nathrath, M.
Genome-wide analysis of somatic copy number alterations and chromosomal breakages in osteosarcoma.Zhang, W. ; Chen, J. ; Wu, M. ; Zhang, X. ; Zhang, M. ; Yue, L. ; Li, Y. ; Liu, J. ; Li, B. ; Shen, F. ; Wang, Y. ; Bai, L. ; Protzer, U. ; Levrero, M. ; Yuan, Z.
PRMT5 restricts hepatitis B virus replication via epigenetic repression of cccDNA transcription and interference with pgRNA encapsidation.Kosinska, A. ; Bauer, T. ; Protzer, U.
Therapeutic vaccination for chronic hepatitis B.Nößner, E.
DGK-α: A checkpoint in cancer-mediated Immuno-inhibition and target for immunotherapy.Entfellner, E. ; Frei, M. ; Christiansen, G. ; Deng, L. ; Blom, J. ; Kurmayer, R.
Evolution of anabaenopeptin peptide structural variability in the cyanobacterium planktothrix.Zhernov, Y.V. ; Kremb, S. ; Helfer, M. ; Schindler, M. ; Harir, M. ; Mueller, C. ; Hertkorn, N. ; Avvakumova, N.P. ; Konstantinov, A.I. ; Brack-Werner, R. ; Schmitt-Kopplin, P. ; Perminova, I.V.
Supramolecular combinations of humic polyanions as potent microbicides with polymodal anti-HIV-activities.Xia, Y. ; Carpentier, A. ; Cheng, X. ; Block, P.D. ; Zhao, Y. ; Zhang, Z. ; Protzer, U. ; Jake Liang, T.
Human stem cell-derived hepatocytes as a model for hepatitis B virus infection, spreading and virus-host interactions.Bohne, F. ; Quitt, O. ; Hasreiter, J. ; Luo, S. ; Bockmann, J.H. ; Tedjokusumo, R. ; Momburg, F. ; Protzer, U.
BI-and trispecific antibodyconstructs mediate specific TCell retargeting towards and elimination of HBV-positive hepatocytes and tumor cells.Michler, T. ; Kosinska, A. ; Jager, C. ; Röder, N. ; Grimm, D. ; Heikenwälder, M. ; Roggendorf, M. ; Protzer, U.
RNA interference mediated suppression of HBV transcripts restores HBV-specific immunity and enhances the efficacy of therapeutic vaccination.Xia, Y. ; Carpentier, A. ; Zhang, Z. ; Protzer, U. ; Liang, T.J.
Hepatitis B virus infection of human stem cells-derived hepatocyte-like cells.Karimzadeh, H. ; Budeus, B. ; Kosinska, A. ; Bauer, T. ; Heinold, A. ; Hoffmann, D. ; Protzer, U. ; Roggendorf, M.
Correlation of mutations within HDV-protein with HLA Backgrounds of patients leads to identification of novel CD8 T cell epitopes.Koppe, C. ; Reisinger, F. ; Verheugd, P. ; Gautheron, J. ; Roderburg, C. ; Tacke, F. ; Preisinger, C. ; Luescher, B. ; Vucur, M. ; Trautwein, C. ; Heikenwälder, M. ; Luedde, T.
Ikkalpha/beta regulate hepatocarcinogenesis and biliary homeostasis by controlling RIPK1 activity.Issels, R.D. ; Bueclein, V. ; Kampmann, E. ; Knoesel, T. ; Nößner, E. ; Subklewe, M. ; Lindner, L.
Dissecting the role of tumor-infiltrating lymphocytes (TIL) in patients with high-risk soft-tissue sarcoma (STS) receiving neo-adjuvant chemotherapy (NAC) with regional hyperthermia (RHT).Tao, S. ; Tao, R. ; Patra, M. ; Drexler, I.
The subcellular localization of viral antigen after infection shapes the antigenic profile and protective capacity of poxvirus-mediated T cell immunity.Greiner, T. ; Bolduan, S. ; Hertel, B. ; Groß, C. ; Hamacher, K. ; Schubert, U. ; Moroni, A. ; Thiel, G.
Ion channel activity of Vpu proteins is conserved throughout evolution of HIV-1 and SIV.Ben-Neriah, Y. ; Lasrey, A. ; Aran, D. ; Zinger, A. ; Finkin, S. ; Stein, I. ; Yuan, D.T. ; Hellman, A. ; Heikenwälder, M. ; Pikarsky, E.
A variety of cancer-associated inflammatory reactions.Keller, I.E. ; Dann, A. ; Lukas, C. ; Brech, D. ; Vosyka, O. ; Nössner, E. ; Eickelberg, O. ; Meiners, S.
Proteasome-dependent Mhc I antigen presentation is altered by cigarette smoke.Pikarsky, E. ; Heikenwälder, M.
Focal and Local: Ectopic lymphoid structures and aggregates of myeloid and other immune cells in liver.Muschaweckh, A. ; Buchholz, V.R. ; Fellenzer, A. ; Hessel, C. ; König, P.A ; Tao, S. ; Tao, R. ; Heikenwälder, M. ; Busch, D.H. ; Korn, T. ; Kastenmüller, G. ; Drexler, I. ; Gasteiger, G.
Antigen-dependent competition shapes the local repertoire of tissue-resident memory CD8+ T cells.Mayorga, O. ; Bühler, S. ; Jaeger, V.K. ; Bally, S. ; Hatz, C. ; Frösner, G. ; Protzer, U. ; van Damme, P. ; Egger, M. ; Herzog, C.
Single-dose Hepatitis A immunization: 7.5-year observational pilot study in nicaraguan children to assess protective effectiveness and humoral immune memory response.Li, Y. ; Xia, Y. ; Han, M. ; Chen, G. ; Zhang, D. ; Thasler, W.E. ; Protzer, U. ; Ning, Q.
IFN-alpha-mediated Base Excision Repair Pathway Correlates with Antiviral Response Against Hepatitis B Virus Infection.Koppe, C. ; Gautheron, J. ; Vucur, M. ; Roderburg, C. ; Tacke, F. ; Trautwein, C. ; Heikenwälder, M. ; Luedde, T.
A new molecular interaction between IKK alpha/beta and RIPK1 regulates biliary homeostasis and hepatocarcinogenesis.Sunami, Y. ; Ringelhan, M. ; Kokai, E. ; Lu, M. ; O'Connor, T. ; Lorentzen, A.R. ; Weber, A. ; Rodewald, A. ; Müllhaupt, B. ; Terracciano, L. ; Gul, S. ; Wissel, S. ; Leithäuser, F. ; Krappmann, D. ; Riedl, P. ; Hartmann, D. ; Schirmbeck, R. ; Strnad, P. ; Hüser, N. ; Kleeff, J. ; Friess, H. ; Schmid, R.M. ; Geisler, F. ; Wirth, T. ; Heikenwälder, M.
Canonical NF-kappa B signaling in hepatocytes acts as a tumor-suppressor in hepatitis B virus surface antigen-driven hepatocellular carcinoma by controlling the unfolded protein response.Rollier, C.S. ; Verschoor, E.J. ; Verstrepen, B.E. ; Drexhage, J.A.R. ; Paranhos-Baccala, G. ; Liljeström, P. ; Sutter, G. ; Arribillaga, L. ; Lasarte, J.J. ; Bartosch, B. ; Cosset, F.L. ; Inchauspe, G. ; Heeney, J.L.
T- and B-cell responses to multivalent prime-boost DNA and viral vectored vaccine combinations against hepatitis C virus in non-human primates.Berger, E. ; Rath, E. ; Yuan, D.T. ; Waldschmitt, N. ; Khaloian, S. ; Allgäuer, M. ; Staszewski, O. ; Lobner, E.M. ; Schöttl, T. ; Giesbertz, P. ; Coleman, O.I. ; Prinz, M. ; Weber, A. ; Gerhard, M. ; Klingenspor, M. ; Janssen, K.P. ; Heikenwälder, M. ; Haller, D.
Mitochondrial function controls intestinal epithelial stemness and proliferation.Lehmann, J. ; Vomacka, J. ; Esser, K. ; Nodwell, M. ; Kolbe, K. ; Raemer, P. ; Protzer, U. ; Reiling, N. ; Sieber, S.A.
Human lysosomal acid lipase inhibitor lalistat impairs Mycobacterium tuberculosis growth by targeting bacterial hydrolases.Jäckel, C. ; Nogueira, M.S. ; Ehni, N. ; Kraus, C. ; Ranke, J. ; Dohmann, M. ; Nößner, E. ; Nelson, P.J.
A vector platform for the rapid and efficient engineering of stable complex transgenes.Eggert, T. ; Wolter, K. ; Ji, J. ; Ma, C. ; Yevsa, T. ; Klotz, S. ; Medina-Echeverz, J. ; Longerich, T. ; Forgues, M. ; Reisinger, F. ; Heikenwälder, M. ; Wang, X.W. ; Zender, L. ; Greten, T.F.
Distinct functions of senescence-associated immune responses in liver tumor surveillance and tumor progression.Brinkmann, C. ; Nehlmeier, I. ; Walendy-Gnirß, K. ; Nehls, J. ; González Hernández, M. ; Hoffmann, M. ; Qiu, X. ; Takada, A. ; Schindler, M. ; Pöhlmann, S.
Tetherin antagonism by the Ebola virus glycoprotein requires an intact receptor-binding domain and can be blocked by GP1-specific antibodies.Protzer, U. ; Knolle, P.A.
"To be or not to be": Immune tolerance in chronic hepatitis B.Gaber, H. ; Abdellatif, A.
Liver research in the International Space Station.Göttesdorfer, I.
Identifizierung transkriptionell aktivierter humaner endogener Retroviren (HERVs) in Tumorerkrankungen.Jager, C.
Therapeutic vaccination using MVA-vectors in a murine model of chronic HBV infection.Masouris, I.
Verteilung und zytotoxische Qualität von T-Zellen und natürlichen Killerzellen im klarzelligen Nierenzellkarzinom: Gefäßsystem-bezogene Lokalisation und Ausstattung mit Perforin beeinflussen Metastasierung und Tumor-spezifisches Überleben.Yuan, D.T.
Investigation of environmental and epigenetic etiologies driving cholangiolar and hepatocellular neoplasias.Bayer, K. ; Banning, C. ; Bruss, V. ; Wiltzer-Bach, L. ; Schindler, M.
Hepatitis C virus is released via a non-canonical secretory route.Boeckl, K. ; Körber, N. ; Barabas, S. ; Demi, L. ; Bauer, T.
An optimized IFN-gamma ELISpot assay using T-activated (R) proteins for determination of CMV-specific cell-mediated immunity.Mayorga, O. ; Bühler, S. ; Jaeger, V.K. ; Bally, S. ; Hatz, C. ; Frösner, G. ; Protzer, U. ; van Damme, P. ; Egger, M. ; Herzog, C.
Single dose hepatitis A immunisation: 7.5 year observational pilot study in Nicaraguan children to assess protective effectiveness and humoral immune memory response.Scherr, A.L. ; Gdynia, G. ; Salou, M. ; Radhakrishnan, P. ; Duglova, K. ; Heller, A. ; Keim, S. ; Kautz, N. ; Jassowicz, A. ; Elssner, C. ; He, Y.W. ; Jaeger, D. ; Heikenwälder, M. ; Schneider, M. ; Weber, A. ; Roth, W. ; Schulze-Bergkamen, H. ; Koehler, B.C.
Bcl-xL is an oncogenic driver in colorectal cancer.Wolf, B. ; Krieg, K. ; Falk, C. ; Breuhahn, K. ; Keppeler, H. ; Biedermann, T. ; Schmid, E. ; Warmann, S. ; Fuchs, J. ; Vetter, S. ; Thiele, D. ; Nieser, M. ; Avci-Adali, M. ; Skokowa, Y. ; Schöls, L. ; Hauser, S.L. ; Ringelhan, M. ; Yevsa, T. ; Heikenwälder, M. ; Kossatz-Boehlert, U.
Inducing differentiation of premalignant hepatic cells as a novel therapeutic strategy in hepatocarcinoma.Lesina, M. ; Wörmann, S.M. ; Morton, J. ; Diakopoulos, K.N. ; Korneeva, O. ; Wimmer, M. ; Einwächter, H. ; Sperveslage, J. ; Demir, I.E. ; Kehl, T. ; Saur, D. ; Sipos, B. ; Heikenwälder, M. ; Steiner, J.M. ; Wang, T.C. ; Sansom, O.J. ; Schmid, R.M. ; Algül, H.
RelA regulates CXCL1/CXCR2-dependent oncogene-induced senescence in murine Kras-driven pancreatic carcinogenesis.Saito, Y. ; Ellegast, J.M. ; Rafiei, A. ; Song, Y. ; Kull, D. ; Heikenwälder, M. ; Rongvaux, A. ; Halene, S. ; Flavell, R.A. ; Manz, M.G.
Peripheral blood CD34+ cells efficiently engraft human cytokine knock-in mice.Endig, J. ; Buitrago-Molina, L.E. ; Marhenke, S. ; Reisinger, F. ; Saborowski, A. ; Schütt, J. ; Limbourg, F. ; Könecke, C. ; Schreder, A. ; Michael, A. ; Misslitz, A.C. ; Healy, M.E. ; Geffers, R. ; Clavel, T. ; Haller, D. ; Unger, K. ; Finegold, M. ; Weber, A. ; Manns, M.P. ; Longerich, T. ; Heikenwälder, M. ; Vogel, A.
Dual role of the adaptive immune system in liver injury and hepatocellular carcinoma development.Rivkin, M. ; Simerzin, A. ; Zorde-Khvalevsky, E. ; Chai, C. ; Yuval, J.B. ; Rosenberg, N. ; Harari-Steinfeld, R. ; Schneider, R. ; Amir, G. ; Condiotti, R. ; Heikenwälder, M. ; Weber, A. ; Schramm, C. ; Wege, H. ; Kluwe, J. ; Galun, E. ; Giladi, H.
Inflammation-induced expression and secretion of microRNA 122 leads to reduced blood levels of kidney-derived erythropoietin and anemia.Michler, T. ; Große, S. ; Mockenhaupt, S. ; Röder, N. ; Stückler, F. ; Knapp, B. ; Ko, C. ; Heikenwälder, M. ; Protzer, U. ; Grimm, D.
Blocking sense-strand activity improves potency, safety and specificity of anti-hepatitis B virus short hairpin RNA.Schirmer, D. ; Gruenewald, T.G.P. ; Klar, R. ; Schmidt, O. ; Wohlleber, D. ; Rubio, R.A. ; Uckert, W. ; Thiel, U. ; Bohne, F. ; Busch, D.H. ; Krackhardt, A.M. ; Burdach, S. ; Richter, G.H.S.
Transgenic antigen-specific, HLA-A*02:01-allo-restricted cytotoxic T cells recognize tumor-associated target antigen STEAP1 with high specificity.Bücklein, V.L. ; Adunka, T. ; Mendler, A.N. ; Issels, R.D. ; Subklewe, M. ; Schmollinger, J.C. ; Nößner, E.
Progressive natural killer cell dysfunction associated with alterations in subset proportions and receptor expression in soft-tissue sarcoma patients.Hagemeyer, N. ; Kierdorf, K. ; Frenzel, K. ; Xue, J. ; Ringelhan, M. ; Abdullah, Z. ; Godin, I. ; Wieghofer, P. ; Costa Jordão, M.J. ; Ulas, T. ; Yorgancioglu, G. ; Rosenbauer, F. ; Knolle, P.A. ; Heikenwälder, M. ; Schultze, J.L. ; Prinz, M.
Transcriptome-based profiling of yolk sac-derived macrophages reveals a role for Irf8 in macrophage maturation.Höckendorf, U. ; Yabal, M. ; Herold, T. ; Munkhbaatar, E. ; Rott, S. ; Jilg, S. ; Kauschinger, J. ; Magnani, G. ; Reisinger, F. ; Heuser, M. ; Kreipe, H. ; Sotlar, K. ; Engleitner, T. ; Rad, R. ; Weichert, W. ; Peschel, C. ; Ruland, J. ; Heikenwälder, M. ; Spiekermann, K. ; Slotta-Huspenina, J. ; Groß, O. ; Jost, P.J.
RIPK3 restricts myeloid leukemogenesis by promoting cell death and differentiation of leukemia initiating cells.Weber, A. ; Heikenwälder, M.
P(URI)fying novel drivers of NASH and HCC: A feedforward loop of IL17A via white adipose tissue.Koppe, C. ; Verheugd, P. ; Gautheron, J. ; Reisinger, F. ; Kreggenwinkel, K. ; Roderburg, C. ; Quagliata, L. ; Terracciano, L. ; Gassler, N. ; Tolba, R.H. ; Boege, Y. ; Weber, A. ; Karin, M. ; Luedde, M. ; Neumann, U.P. ; Weiskirchen, R. ; Tacke, F. ; Vucur, M. ; Trautwein, C. ; Lüscher, B. ; Preisinger, C. ; Heikenwälder, M. ; Luedde, T.
IκB kinaseα/β control biliary homeostasis and hepatocarcinogenesis in mice by phosphorylating the cell-death mediator receptor-interacting protein kinase 1.Höhne, K. ; Businger, R. ; van Nuffel, A. ; Bolduan, S. ; Koppensteiner, H. ; Baeyens, A. ; Vermeire, J. ; Malatinkova, E. ; Verhasselt, B. ; Schindler, M.
Virion encapsidated HIV-1 Vpr induces NFAT to prime non-activated T cells for productive infection.Chachage, M. ; Pollakis, G. ; Kuffour, E.O. ; Haase, K. ; Bauer, A. ; Nadai, Y. ; Podola, L. ; Clowes, P. ; Schiemann, M. ; Henkel, L. ; Hoffmann, D. ; Joseph, S.S. ; Bhuju, S. ; Maboko, L. ; Sarfo, F.S. ; Eberhardt, K. ; Hoelscher, M. ; Feldt, T. ; Saathoff, E. ; Geldmacher, C.
CD25+ FoxP3+ memory CD4 T cells are frequent targets of HIV infection in vivo.Homs, M. ; Rodriguez-Frias, F. ; Gregori, J. ; Ruiz, A. ; Reimundo, P. ; Casillas, R. ; Tabernero, D. ; Godoy, C. ; Barakat, S. ; Quer, J. ; Riveiro-Barciela, M. ; Roggendorf, M. ; Esteban, R. ; Buti, M.
Evidence of an exponential decay pattern of the hepatitis delta virus evolution rate and fluctuations in quasispecies complexity in long-term studies of chronic delta infection.Mall, S. ; Yusufi, N. ; Wagner, R. ; Klar, R. ; Bianchi, H. ; Steiger, K. ; Straub, M. ; Audehm, S. ; Laitinen, I. ; Aichler, M. ; Peschel, C. ; Ziegler, S. ; Mustafa, M. ; Schwaiger, M. ; D'Alessandria, C. ; Krackhardt, A.M.
Immuno-PET imaging of engineered human T cells in tumors.Späth, P.M. ; Hoffmann, D. ; Spitzenberger, F.
Der Einfluss der DIN EN ISO 15189 auf die Ergebnissicherheit in der Virusdiagnostik.Broadley, S.P. ; Plaumann, A. ; Coletti, R. ; Lehmann, C. ; Wanisch, A. ; Seidlmeier, A. ; Esser, K. ; Luo, S. ; Rämer, P.C. ; Massberg, S. ; Busch, D.H. ; van Lookeren Campagne, M. ; Verschoor, A.
Dual-track clearance of circulating bacteria balances rapid restoration of blood sterility with induction of adaptive immunity.Thomsen, M.K. ; Nandakumar, R. ; Stadler, D. ; Malo, A. ; Valls, R.M. ; Wang, F. ; Reinert, L.S. ; Dagnaes-Hansen, F. ; Hollensen, A.K. ; Mikkelsen, J.G. ; Protzer, U. ; Paludan, S.R.
Lack of immunological DNA sensing in hepatocytes facilitates hepatitis B virus infection.Wisskirchen, K. ; Metzger, K. ; Weigand, L. ; Kieback, E. ; Sprinzl, M. ; Uckert, W. ; Busch, D.H. ; Krackhardt, A.M. ; Protzer, U.
Functional characterization of OF HBV-specific T cell receptors for redirection of T cells against HBV-infected hepatocytes.Körber, N. ; Behrends, U. ; Hapfelmeier, A. ; Protzer, U. ; Bauer, T.
Validation of an IFNγ/IL2 FluoroSpot assay for clinical trial monitoring.Spinner, S. ; Crispatzu, G. ; Yi, J.H. ; Munkhbaatar, E. ; Mayer, P. ; Höckendorf, U. ; Müller, N. ; Li, Z. ; Schader, T. ; Bendz, H. ; Hartmann, S. ; Yabal, M. ; Pechloff, K. ; Heikenwälder, M. ; Kelly, G.L. ; Strasser, A. ; Peschel, C. ; Hansmann, M.L. ; Ruland, J. ; Keller, U. ; Newrzela, S. ; Herling, M. ; Jost, P.J.
Re-activation of mitochondrial apoptosis inhibits T-cell lymphoma survival and treatment resistance.Mejías-Luque, R. ; Zöller, J. ; Anderl, F. ; Loew-Gil, E. ; Vieth, M. ; Adler, T. ; Engler, D.B. ; Urban, S. ; Browning, J.L. ; Müller, A. ; Gerhard, M. ; Heikenwälder, M.
Lymphotoxin β receptor signalling executes Helicobacter pylori-driven gastric inflammation in a T4SS-dependent manner.Blank, T. ; Detje, C.N. ; Spieß, A. ; Hagemeyer, N. ; Brendecke, S.M. ; Wolfart, J. ; Staszewski, O. ; Zöller, T. ; Papageorgiou, I. ; Schneider, J. ; Paricio-Montesinos, R. ; Eisel, U.L. ; Manahan-Vaughan, D. ; Jansen, S. ; Lienenklaus, S. ; Lu, B. ; Imai, Y. ; Müller, M. ; Goelz, S.E. ; Baker, D.P. ; Schwaninger, M. ; Kann, O. ; Heikenwälder, M. ; Kalinke, U. ; Prinz, M.
Brain endothelial- and epithelial-specific interferon receptor chain 1 drives virus-induced sickness behavior and cognitive impairment.Blondot, M.L. ; Bruss, V. ; Kann, M.
Intracellular transport and egress of hepatitis B virus.Lucifora, J. ; Protzer, U.
Attacking hepatitis B virus cccDNA - the holy grail to hepatitis B cure.Neff, F. ; Kirsch, D.G. ; Saur, D. ; Schmid, R.M. ; Bazhin, A.V. ; Heikenwälder, M. ; Siveke, J.T.
Targeting notch for myeloid reprogramming in pancreatic cancer.Friemel, I. ; Rechsteiner, M.P. ; Frick, L. ; Boehm, F. ; Struckmann, K. ; Egger, M. ; Moch, N. ; Heikenwälder, M. ; Weber, A.
Intratumor heterogeneity in hepatocellular carcinoma: Impact on tumor classifications and targeted therapies.Beyer, M. ; Abdullah, Z. ; Chemnitz, J.M. ; Maisel, D. ; Sander, J. ; Lehmann, C. ; Thabet, Y. ; Shinde, P.V. ; Schmidleithner, L. ; Köhne, M. ; Trebicka, J. ; Schierwagen, R. ; Hofmann, A. ; Popov, A. ; Lang, K.S. ; Oxenius, A. ; Buch, T. ; Kurts, C. ; Heikenwälder, M. ; Fätkenheuer, G. ; Lang, P.A. ; Hartmann, P. ; Knolle, P.A. ; Schultze, J.L.
Tumor-necrosis factor impairs CD4+ T cell-mediated immunological control in chronic viral infection.Ma, C. ; Kesarwala, A.H. ; Eggert, T. ; Medina-Echeverz, J. ; Kleiner, D.E. ; Jin, P. ; Stroncek, D.F. ; Terabe, M. ; Kapoor, V. ; ElGindi, M. ; Han, M. ; Thornton, A.M. ; Zhang, H. ; Egger, M. ; Luo, J. ; Felsher, D.W. ; McVicar, D.W. ; Weber, A. ; Heikenwälder, M. ; Greten, T.F.
NAFLD causes selective CD4+ T lymphocyte loss and promotes hepatocarcinogenesis.Broecker, F. ; Hardt, C. ; Herwig, R. ; Timmermann, B. ; Kerick, M. ; Wunderlich, A. ; Schweiger, M.R. ; Borsig, L. ; Heikenwälder, M. ; Lehrach, H. ; Moelling, K.
Transcriptional signature induced by a C-terminal c-Src mutant in a human breast cell line.Matter, M.S. ; Marquardt, J.U. ; Andersen, J.B. ; Quintavalle, C. ; Korokhov, N. ; Stauffer, J.K. ; Kaji, K. ; Decaens, T. ; Quagliata, L. ; Elloumi, F. ; Hoang, T. ; Molinolo, A. ; Conner, E.A. ; Weber, A. ; Heikenwälder, M. ; Factor, V.M. ; Thorgeirsson, S.S.
Oncogenic driver genes and the inflammatory microenvironment dictate liver tumor phenotype.Bartmann, J. ; Frankenberger, M. ; Neurohr, C. ; Eickelberg, O. ; Nößner, E. ; von Wulffen, W.
A novel role of MMP-13 for murine DC function: Its inhibition dampens T cell activation.Maresch, R. ; Müller, S. ; Veltkamp, C. ; Öllinger, R. ; Friedrich, M. ; Heid, I.M. ; Steiger, K. ; Weber, J. ; Engleitner, T. ; Barenboim, M. ; Klein, S. ; Louzada, S. ; Banerjee, R. ; Strong, A. ; Stauber, T. ; Gross, N. ; Geumann, U. ; Lange, S. ; Ringelhan, M. ; Varela, I. ; Unger, K. ; Yang, F. ; Schmid, R.M. ; Vassiliou, G.S. ; Braren, R. ; Schneider, G. ; Heikenwälder, M. ; Bradley, A. ; Saur, D. ; Rad, R.
Multiplexed pancreatic genome engineering and cancer induction by transfection-based CRISPR/Cas9 delivery in mice.Sunami, Y. ; Ringelhan, M. ; Kokai, E. ; Lu, M. ; O'Connor, T. ; Lorentzen, A.R. ; Weber, A. ; Rodewald, A.K. ; Müllhaupt, B. ; Terracciano, L. ; Gul, S. ; Wissel, S. ; Leithäuser, F. ; Krappmann, D. ; Riedl, P. ; Hartmann, D. ; Schirmbeck, R. ; Strnad, P. ; Hüser, N. ; Kleeff, J. ; Friess, H. ; Schmid, R.M. ; Geisler, F. ; Wirth, T. ; Heikenwälder, M.
Canonical NF-κB signaling in hepatocytes acts as a tumor-suppressor in HBV surface antigen-driven HCC by controlling the UPR.Kammerl, I.E. ; Dann, A. ; Mossina, A. ; Brech, D. ; Lukas, C. ; Vosyka, O. ; Nathan, P. ; Conlon, T.M. ; Wagner, D.E. ; Overkleeft, H.S. ; Prasse, A. ; Rosas, I.O. ; Straub, T. ; Krauss-Etschmann, S. ; Königshoff, M. ; Preissler, G. ; Winter, H. ; Lindner, M. ; Hatz, R.A. ; Behr, J. ; Heinzelmann, K. ; Yildirim, A.Ö. ; Nößner, E. ; Eickelberg, O. ; Meiners, S.
Impairment of immunoproteasome function by cigarette smoke and in COPD.O'Rourke, A. ; Kremb, S. ; Bader, T.M. ; Helfer, M. ; Schmitt-Kopplin, P. ; Gerwick, W.H. ; Brack-Werner, R. ; Voolstra, C.R.
Alkaloids from the sponge Stylissa carteri present prospective scaffolds for the inhibition of Human Immunodeficiency Virus 1 (HIV-1).Saugel, B. ; Jakobus, J. ; Huber, W. ; Hoffmann, D. ; Holzapfel, K. ; Protzer, U. ; Schmid, R.M. ; Umgelter, A.
Herpes simplex virus in bronchoalveolar lavage fluid of medical intensive care unit patients: Association with lung injury and outcome.Rebensburg, S. ; Helfer, M. ; Schneider, M. ; Koppensteiner, H. ; Eberle, J. ; Schindler, M. ; Gürtler, L. ; Brack-Werner, R.
Potent in vitro antiviral activity of Cistus incanus extract against HIV and Filoviruses targets viral envelope proteins.Roblek, M. ; Strutzmann, E. ; Zankl, C. ; Adage, T. ; Heikenwälder, M. ; Atlic, A. ; Weis, R. ; Kungl, A. ; Borsig, L.
Targeting of CCL2-CCR2-glycosaminoglycan axis using a CCL2 decoy protein attenuates metastasis through inhibition of tumor cell seeding.Backes, S. ; Jager, C. ; Dembek, C.J. ; Kosinska, A. ; Bauer, T. ; Stephan, A.-S. ; Dišlers, A. ; Mutwiri, G. ; Busch, D.H. ; Babiuk, L.A. ; Gasteiger, G. ; Protzer, U.
Protein-prime/modified vaccinia virus Ankara vector-boost vaccination overcomes tolerance in high-antigenemic HBV-transgenic mice.Geipel, A. ; Seiz, P.L. ; Niekamp, H. ; Neumann-Fraune, M. ; Zhang, K. ; Kaiser, R. ; Protzer, U. ; Gerlich, W.H. ; Glebe, D. ; HOPE Consortium ()
Entecavir allows an unexpectedly high residual replication of HBV mutants resistant to lamivudine.Bonaccorsi-Riani, E. ; Pennycuick, A. ; Londoño, M.C. ; Lozano, J.J. ; Benítez, C. ; Sawitzki, B. ; Martínez-Picola, M. ; Bohne, F. ; Martínez-Llordella, M. ; Miquel, R. ; Rimola, A. ; Sánchez-Fueyo, A.
Molecular characterization of acute cellular rejection occurring during intentional immunosuppression withdrawal in liver transplantation.Hoellein, A. ; Hecker, J. ; Hoffmann, D. ; Göttle, F. ; Protzer, U. ; Peschel, C. ; Götze, K.
Serious outbreak of human metapneumovirus in patients with hematologic malignancies.Wimmer, P. ; Berscheminski, J. ; Blanchette, P. ; Groitl, P. ; Branton, P.E. ; Hay, R.T. ; Dobner, T. ; Schreiner, S.
PML isoforms IV and V contribute to adenovirus-mediated oncogenic transformation by functionally inhibiting the tumor-suppressor p53.Nowicka, A.M. ; Häuselmann, I. ; Borsig, L. ; Bolduan, S. ; Schindler, M. ; Schraml, P. ; Heikenwälder, M. ; Moch, H.
A novel pVHL-independent but NEMO-driven pathway in renal cancer promotes HIF stabilization.Berscheminski, J. ; Brun, J. ; Speiseder, T. ; Wimmer, P. ; Ip, W.H. ; Terzic, M. ; Dobner, T. ; Schreiner, S.
Sp100A is a tumor suppressor that activates p53-dependent transcription and counteracts E1A/E1B-55K-mediated transformation.Meredith, L.W. ; Hu, K. ; Cheng, X. ; Howard, C.R. ; Baumert, T.F. ; Balfe, P. ; van de Graaf, K.F. ; Protzer, U. ; McKeating, J.A.
Lentiviral hepatitis B pseudotype entry requires NTCP and additional hepatocyte-specific factors.Sautto, G.A. ; Wisskirchen, K. ; Clementi, N. ; Castelli, M. ; Diotti, R.A. ; Graf, J. ; Clementi, M. ; Burioni, R. ; Protzer, U. ; Mancini, N.
Chimeric Antigen Receptor (CAR)-engineered T cells redirected against Hepatitis C Virus (HCV) E2 glycoprotein.