Molecular Targets and Therapeutics Center
Institute of Functional Epigenetics
At the Institute of Functional Epigenetics (IFE), we aim to uncover how epigenetic information is stored and how the environment controls our epigenome to identify novel therapeutic targets.
At the Institute of Functional Epigenetics (IFE), we aim to uncover how epigenetic information is stored and how the environment controls our epigenome to identify novel therapeutic targets.
IFE Members
Deputy Director of the Institute of Functional Epigenetics
Group Leader, Institute of Functional Epigenetics, Molecular Targets & Therapeutics Center
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Latest Publications
Moukham, H. ; Caligaris, M. ; Six, P. ; Padovani, F. ; Schmoller, K.M. ; Virgilio, C.D. ; Nicastro, R. ; Tripodi, F. ; Coccetti, P.
SNF1/AMPK controls its own localization by phosphorylating its activating kinase Sak1.Wunder, T. ; Eulitz, L. ; Kramer, L. ; Ali, Z.M. ; Ostermeier, M. ; Leu, C. ; Szulc, B. ; Holzner, L.J. ; Fechter, J. ; Padovani, F. ; Brandt, B. ; Girr, P. ; Teh, J.T. ; Mühlbauer, S. ; Sotos, C. ; Angstenberger, M. ; Mackinder, L.C.M. ; Schmoller, K.M. ; Rädler, J.O. ; Nickelsen, J. ; de Vries, J. ; Kunz, H.H.
Conserved and lineage-specific roles of KEA-mediated Ion homeostasis in chlamydomonas.Dengler, L. ; Padovani, F. ; Lemke, B. ; Brugger, R. ; Benedikt, A. ; Westermann, B. ; Maček, B. ; Schmoller, K.M. ; Ewald, J.C.
In the absence of mitochondrial fusion unequal segregation of mitochondria drives mtDNA loss.Kim, J. ; Xie, S. ; Valenzuela, L.F. ; Xiao, J. ; Lanz, M.C. ; Gao, X. ; Swaffer, M. ; Mitchell, C.E. ; Rubin, S.M. ; Schmoller, K.M. ; Skotheim, J.M.
A Fkh1/2 binding site array in the WHI5 promoter drives sub-scaling transcription.Balan, T. ; Petitalot, A. ; Albert, J.R. ; Abbou, L. ; Chevreux, G. ; Al-Sady, B. ; Aygenli, B.Ö. ; Bartke, T. ; Margueron, R. ; Duharcourt, S.
A H3K27me3 reader complex couples H3K27me3 accumulation to nascent transcription of transposable elements in Paramecium.Langstein-Skora, I. ; Schmid, A. ; Huth, F. ; Shabani, D. ; Spechtenhauser, L. ; Likhodeeva, M. ; Kunert, F. ; Metzner, F.J. ; Emenecker, R.J. ; Richardson, M.O. ; Aftab, W. ; Götz, M.J. ; Payer, S. ; Pietrantoni, N. ; Valka, V. ; Ravichandran, S.K. ; Bartke, T. ; Karl-Peter, H. ; Gerland, U. ; Korber, P. ; Holehouse, A.S.
Sequence and chemical specificity define the functional landscape of intrinsically disordered regions.Papa, C. ; Rose, A. ; Martin, H.N.G. ; Useini, A. ; Geier, F. ; Liao, L. ; Rodriguez Aguilera, J.R. ; Valina-Allo, P. ; Hoffmann, A. ; Tvardovskiy, A. ; Zulfqar, F. ; Zimmerman, A. ; Schicht, G. ; Ott, F. ; Körner, C. ; Engelmann, B. ; Rolle-Kampczyk, U. ; von Bergen, M. ; Meier, M. ; Bartke, T. ; Seehofer, D. ; Klöting-Blüher, N. ; Matz-Soja, M. ; Damm, G. ; Boeckel, J.N. ; Buescher, J.M. ; Blüher, M. ; Laufs, U. ; Bondareva, O. ; Sträter, N. ; Künze, G. ; Heiker, J.T. ; Sheikh, B.N.
Bempedoic acid directly binds and activates PPARα.Proulx-Giraldeau, F. ; Gao, X. ; Chadha, Y. ; Xiao, J.Y. ; Schmoller, K.M. ; Skotheim, J.M. ; François, P.
Division asymmetry drives cell size variability in budding yeast.Thoma, F. ; Hagen, J. ; Rathberger, R. ; Padovani, F. ; Hörl, D. ; Schmoller, K.M. ; Osman, C.
Local mitochondrial physiology defined by mtDNA quality guides purifying selection.Nitsch, S. ; Coraor, A.E. ; Schauer, T. ; Wu, Y. ; Sun, J. ; Möritz, N. ; Funke, J.J. ; Nagpal, H. ; Chua, G.N.L. ; Battistini, F. ; Lauberth, S.M. ; Richard, E.M. ; Orozco, M. ; Liu, S. ; Desviat, L.R. ; Fierz, B. ; Dietz, H. ; Roeder, R.G. ; de Pablo, J.J. ; Schneider, R.
H4K16 acylations destabilize chromatin architecture and facilitate transcriptional response during metabolic perturbations.Oak, M.S. ; Stock, M. ; Janeva, A. ; Mezes, M. ; Hynes-Allen, A.M. ; Straub, T. ; Forné, I. ; Ettinger, A. ; Hamperl, S. ; Imhof, A. ; van den Ameele, J. ; Scialdone, A. ; Hörmanseder, E.
Pre-marking chromatin with H3K4 methylation is required for accurate zygotic genome activation and development.Padovani, F. ; Stegmaier, T. ; Mairhörmann, B. ; Schmoller, K.M.
Analysis of multidimensional microscopy data using cell-ACDC.Kukhtevich, I. ; Persson, S. ; Padovani, F. ; Schneider, R. ; Cvijovic, M. ; Schmoller, K.M.
The origin of septin ring size control in budding yeast.Iturbide Martinez De Albeniz, A. ; Ruiz Tejada Segura, M.L. ; Noll, C. ; Schorpp, K.K. ; Rothenaigner, I. ; Ruiz-Morales, E.R. ; Lubatti, G. ; Agami, A. ; Hadian, K. ; Scialdone, A. ; Torres-Padilla, M.E.
Addendum: Retinoic acid signaling is critical during the totipotency window in early mammalian development.Keogh, M.C. ; Almouzni, G. ; Andrews, A.J. ; Armache, K.J. ; Arrowsmith, C.H. ; Baek, S.H. ; Bedford, M.T. ; Bernstein, E. ; Côté, J.-A. ; David, Y. ; Denu, J.M. ; Fierz, B. ; Garcia, B.A. ; Glass, K.C. ; Gozani, O. ; Helin, K. ; Henikoff, S. ; Jensen, O.N. ; Josefowicz, S.Z. ; Kelleher, N.L. ; Kutateladze, T.G. ; Lindner, H.H. ; Lu, C. ; Luger, K. ; Mallick, P. ; Musselman, C.A. ; Muir, T.W. ; Pasa-Tolic, L. ; Schneider, R. ; Shi, X. ; Shi, Y. ; Sidoli, S. ; Smith, L.M. ; Tyler, J.K. ; Wolberger, C. ; Workman, J.L. ; Strahl, B.D. ; Young, N.L.
A needed nomenclature for nucleosomes.Our Institute in Numbers
Epigenetics@Helmholtz Munich
Research School EpiCrossBorders
International Training Network Cell2Cell
CRC Chromatin Dynamics
CRC Chemical Biology of Epigenetic Modifications
German Research Foundation
Ludwig-Maximilians-Universität München
Contact Institute Office
