Research Area
Marion received her PhD in Biophysics from Joseph Fourier University in 2007 under Professor Giuseppe Zaccai, where she exploited neutron scattering to explore water dynamics and macromolecular motions directly inside living cells. Her early postdoctoral work in the Department of Professor Wolfgang Baumeister at the Max Planck Institute of Biochemistry was supported by two postdoctoral fellowships (EMBO and Marie Curie fellowships, 2011-2013), and the award of an HFSP Program Grant (2016-2021) gave her the opportunity to start her own subgroup. With Renaud Poincloux / IPBS, she then obtained an ANR-DFG grant (cryoAdhesome, 2020-2024) to establish podosomes as a model system for structure-function analysis of the actin cytoskeleton in a cellular system that has direct implications for in vivo function, such as during bone turnover, tissue and cancer invasion. She also recently built a consortium with teams from the Institut Jacques-Monod, LPTMS and Sorbonne University to model podosome mechanics from the molecular scale up to the mesoscale, and were awarded an MIC grant (2020-2023). In 2022, she joined the Helmholtz Pioneer Campus as a Principal Investigator.
Professional Background
Principal Investigator – Helmholtz Pioneer Campus, Helmholtz Munich
Project Group Leader – Max Planck Institute of Biochemistry
Postdoc (Wolfgang Baumeister) – Max Planck Institute of Biochemistry
Postdoc (Giuseppe Zaccai) – Institut Laue-Langevin (ILL)
Graduate Student (Giuseppe Zaccai and Moevea Tehei) – Institut de Biologie Structurale (IBS)
Master Student (Daniel Riveline) – Laboratoire Interdisciplinaire de Physique (LIPhy)
Student Intern (Nils O. Petersen) – Western University, Department of Chemistry
Honors and Awards
- 2024-2028 ANR-DFG NLE 2024 - Individual Research Grant (ACTIS)
- 2024-2025 Chan Zuckerberg initiative - Cryo-CLEM labels grant
- 2020-2024 ANR-DFG NLE 2020 – Individual Research Grant (CryoAdhesome)
- 2016-2021 Participation in an HFSP Program Grant
- 2012-2013 Marie Curie Intra-European Fellowship
- 2011 EMBO Long-Term Fellowship
- 2008-2009 ILL Postdoctoral Fellowship
- 2004-2007 Graduate Research Fellowship from the French Ministry of Education Grenoble INP Graduate Lecturer Fellowship
- 2003-2004 Joseph Fourier University Masters Scholarship
Publications
Karfusehr, C. ; Eder, M. ; Yang, H.Y. ; Beinsteiner, B. ; Jasnin, M. ; Simmel, F.C.
Self-assembled cell-scale containers made from DNA origami membranes.Merino‐Salomón, A. ; Schneider, J. ; Babl, L. ; Krohn, J.F. ; Sobrinos‐Sanguino, M. ; Schäfer, T. ; Luque-Ortega, J.R. ; Alfonso, C. ; Jimenez, M. ; Jasnin, M. ; Schwille, P. ; Rivas, G.
Crosslinking by ZapD drives the assembly of short FtsZ filaments into toroidal structures in solution.Li, W. ; Li, A. ; Yu, B. ; Zhang, X. ; Liu, X. ; White, K.L. ; Stevens, R.C. ; Baumeister, W. ; Sali, A. ; Jasnin, M. ; Sun, L.
In situ structure of actin remodeling during glucose-stimulated insulin secretion using cryo-electron tomography.Reverte-López, M. ; Kanwa, N. ; Qutbuddin, Y. ; Belousova, V. ; Jasnin, M. ; Schwille, P.
Self-organized spatial targeting of contractile actomyosin rings for synthetic cell division.Schneider, J. ; Jasnin, M.
Molecular architecture of the actin cytoskeleton: From single cells to whole organisms using cryo-electron tomography.Martinez-Sanchez, A. ; Lamm, L. ; Jasnin, M. ; Phelippeau, H.
Simulating the cellular context in synthetic datasets for cryo-electron tomography.
