Dr. Marion Jasnin

Marion received her PhD in Biophysics from Joseph Fourier University in 2007, under the supervision of Giuseppe Zaccai and Moeava Tehei. During this time, she used neutron scattering to study the dynamics of water and macromolecules within living bacterial cells. She then undertook postdoctoral research in Wolfgang Baumeister's Department at the Max Planck Institute of Biochemistry, supported by EMBO and Marie Curie fellowships (2011–2013). Subsequently, the award of an HFSP Program Grant (2016–2021) enabled her to start her own subgroup. In collaboration with Renaud Poincloux at IPBS-Toulouse, she obtained an ANR-DFG grant (CryoAdhesome, 2020–2024) to establish podosomes as a model system for the analysis of the structure and function of the actin cytoskeleton. This cellular system has direct implications for in vivo processes such as bone turnover, tissue invasion, and cancer invasion. In October 2022, she joined the Helmholtz Pioneer Campus at Helmholtz Munich as a Principal Investigator. She obtained an ANR-DFG grant (ACTIS, 2024–2028) to study the actin architecture at immunological synapses in collaboration with the Dupré and Michelot laboratories. She is also contributing to the development of cryo-CLEM labels (CryoEMcapsulins, CZI grant, 2024–2025) in collaboration with Felix Sigmund, as well as to the development of AI-based tools for cryo-ET data analysis in collaboration with Tingying Peng.