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Helmholtz Munich | Alexander Wolf

Helmholtz Munich Team Wins “Frontiers of Science” Award

Awards & Grants, Computational Health, ICB,

A team of computational biologists from Helmholtz Munich has been honored with the "Frontiers of Science" award at the International Congress of Basic Science (ICBS) in Beijing. Researchers Fabian Theis, Alexander Wolf, and Philipp Angerer received this recognition for their 2018 paper, titled “Scanpy: large-scale single-cell gene expression data analysis”.

The International Congress of Basic Science is a globally recognized event that brings together leading scientists, researchers, and scholars from various disciplines to share their latest innovations and discoveries. The “Frontiers of Science” award is a highlight of the congress, honoring researchers who have made significant advancements in their fields.

Pioneering Single-Cell RNA Sequencing Analysis

The Helmholtz Munich co-authors have made a significant impact on the field of genomics and bioinformatics with their development of Scanpy, an innovative computational tool designed for large-scale single-cell RNA sequencing (scRNA-seq) data analysis. Their research addresses a critical challenge in the field: balancing the need for computational accuracy and speed when analyzing massive genomic datasets. Single-cell RNA sequencing is a powerful technique that allows scientists to examine gene expression at the individual cell level, providing unprecedented insights into cellular diversity and function.

One of the most significant implications of this research is its potential impact on personalized medicine and targeted therapies. By improving the accuracy and speed of single-cell analysis, the team’s methods allow scientists to explore the genetic underpinnings of complex diseases more deeply. Since its release in 2018, Scanpy has been widely adopted by the research community, contributing to numerous clinical and other studies. These advancements could lead to breakthroughs in understanding, diagnosing, and treating diseases, ultimately paving the way for more effective and personalized medical interventions.

 

Learn more about Scanpy

Read the award-winning paper

Philipp Angerer

Software engineer

Prof. Dr. Dr. Fabian Theis

Director of Biomedical AI